HANCOCK JOHN INSTITUTIONAL SERIES TRUST
497, 1999-05-03
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      Supplement to the John Hancock Institutional Series Trust Prospectus
          dated July 1, 1998 for John Hancock Independence Growth Fund
                    and John Hancock Independence Value Fund


On April 27, 1999, the Trustees of the John Hancock Independence Growth Fund and
John Hancock  Independence  Value Fund voted to recommend that the  shareholders
adopt a distribution  plan  providing for payments to John Hancock  Funds,  Inc.
("JH  Funds") to provide  certain  services  and to  reimburse  JH Funds for its
expenses in connection with the sale of fund shares.  A shareholder  meeting for
each fund will be held on June 16, 1999.  Shareholders of record on May 10, 1999
will be entitled to vote on this  proposal.  If this plan is approved it will be
suspended until July 1, 2000.



April 28, 1999

KI0PS  4/99





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