HANCOCK JOHN INSTITUTIONAL SERIES TRUST
485APOS, 1999-07-29
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                                                            FILE NO.  33-86102
                                                              FILE NO.  811-8852
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM N-1A
                                   ---------
                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933            (X)
                          Pre-Effective Amendment No.            ( )
                        Post-Effective Amendment No. 11          (X)
                          REGISTRATION STATEMENT UNDER
                       THE INVESTMENT COMPANY ACT OF 1940        (X)
                                Amendment No.  12                (X)
                                   ---------
                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST
               (Exact Name of Registrant as Specified in Charter)
                             101 Huntington Avenue
                        Boston, Massachusetts 02199-7603
              (Address of Principal Executive Offices) (Zip Code)
                 Registrant's Telephone Number, (617) 375-1700
                                   ---------
                                 SUSAN S. NEWTON
                          Vice President and Secretary
                          John Hancock Advisers, Inc.
                             101 Huntington Avenue
                          Boston, Massachusetts 02199
                    (Name and Address of Agent for Service)
                                   ---------

                 APPROXIMATE DATE OF PROPOSED PUBLIC OFFERING:


It is proposed that this filing will become effective:
( ) immediately upon filing pursuant to paragraph (b) of Rule 485
( ) on (date) pursuant to paragraph (b) of Rule 485
( ) 75 days after filing pursuant to paragraph (a) of Rule 485
(X) on October 1, 1999 pursuant to paragraph (a) of Rule 485

If appropiate, check the following box:

( )  This  post-effective  amendment  designates  a  new  effective  date  for a
     previously filed post-effective amendment.



<PAGE>

- --------------------------------------------------------------------------------

                                  Independence
                                  Investment
                                  Associates

                                  CLASS P

                                  [LOGO] Prospectus
                                         October 1, 1999

- --------------------------------------------------------------------------------

As with all mutual funds, the Securities and Exchange Commission has not
approved or disapproved this fund or determined whether the information in this
prospectus is adequate and accurate. Anyone who indicates otherwise is
committing a federal crime.

Independence Growth & Income Fund

[LOGO] Independence Investment Associates, Inc.,
                                and subsidiaries

       53 State Street, Boston, Massachusetts 02109
<PAGE>

Contents

- --------------------------------------------------------------------------------

A summary of the fund's goals,     Independence Growth & Income Fund           4
strategies, risks, performance
and expenses.


Policies and instructions for      Your account
opening, maintaining and
closing an account.                Understanding your expenses                 6
                                   Opening an account                          6
                                   Buying shares                               7
                                   Selling shares                              8
                                   Transaction policies                       10
                                   Dividends and account policies             10


Further information on the         Fund details
fund.
                                   Business structure                         12


                                   For more information               back cover
<PAGE>

Independence Growth & Income Fund

GOAL AND STRATEGY

[Clip Art] The fund seeks above-average total return, consisting of capital
appreciation and income. To pursue this goal, the fund invests in a diversified
portfolio of primarily large-capitalization stocks. The portfolio's risk profile
is substantially similar to that of the S&P 500 Index.

The managers select from a menu of stocks of approximately 550 companies that
evolves over time. Approximately 70% to 80% of these companies also are included
in the S&P 500 Index. The subadviser's investment research team is organized by
industry and tracks these companies to develop earnings estimates and five-year
projections for growth. A series of proprietary computer models use this
in-house research to rank the stocks according to their combination of:

o  value, meaning they appear to be underpriced

o  momentum, meaning they show potential for strong growth

This process, together with a risk/return analysis against the S&P 500 Index,
results in a portfolio of approximately 100 to 130 of the stocks from the top
60% of the menu. The fund must sell any stocks that fall into the bottom 20% of
the menu.

In normal market conditions, the fund is almost entirely invested in stocks.

In abnormal market conditions, the fund may temporarily invest more than 35% of
assets in investment-grade short-term securities. In these and other cases, the
fund might not achieve its goal.

The fund may trade securities actively, which could increase its transaction
costs, thus lowering performance.

================================================================================

SUBADVISER

Independence Investment
Associates, Inc.
- -----------------------------------

Team responsible for day-to-day
investment management

A subsidiary of John Hancock
Mutual Life Insurance Company

Founded in 1982

Supervised by the adviser

PAST PERFORMANCE

[Clip Art] The graph shows how the fund's total return has varied from year to
year, while the table shows performance over time (along with a broad-based
market index for reference). This information may help provide an indication of
the fund's risks. The year-by-year and average annual figures are for Class I
shares, which are offered in a separate prospectus. Annual returns should be
substantially similar since both classes invest in the same portfolio. However,
Class I shares' average annual figures do not reflect 12b-1 fees, which are
imposed on Class P shares. Year-by-year, average annual and index figures do not
reflect these fees and would be lower if they did. All figures assume dividend
reinvestment. Past performance does not indicate future results.

- --------------------------------------------------------------------------------
Class I year-by-year total returns -- calendar years
- --------------------------------------------------------------------------------
                                                  1996      1997      1998

                                                 20.08%    29.49%    30.16%

1999 total return as of March 31: 2.25%
Best quarter: Q4 '98, 25.14%  Worst quarter: Q3 '98, -13.20%

- --------------------------------------------------------------------------------
Class I average annual total returns -- for periods ending 12/31/98
- --------------------------------------------------------------------------------
                                                                 Fund     Index
1 year                                                           30.16%   28.58%
Life of fund - began 3/10/95                                     27.78%   30.20%

Index: Standard &Poor's 500 Stock Index, an unmanaged index of 500 stocks.


4
<PAGE>

MAIN RISKS

[Clip Art] The value of your investment will go up and down in response to stock
market movements. Large-capitalization stocks as a group could fall out of favor
with the market, causing the fund to underperform funds that focus on small- or
medium-capitalization stocks.

The fund's management strategy will influence performance significantly. If the
investment research team's earnings estimates or projections turn out to be
inaccurate, or if the proprietary computer models do not perform as expected,
the fund could underperform its peers or lose money.

To the extent that the fund makes investments with additional risks, those risks
could increase volatility or reduce performance:

o  Foreign investments carry additional risks, including potentially inadequate
   or inaccurate financial information and social or political upheavals.

Investments in the fund are not bank deposits and are not insured or guaranteed
by the Federal Deposit Insurance Corporation or any other government agency. You
could lose money by investing in this fund.

================================================================================

YOUR EXPENSES

[Clip Art] Transaction expenses are charged directly to your account. Operating
expenses are paid from the fund's assets, and therefore are paid by shareholders
indirectly. Because Class P shares are new, their expenses are based on Class I
expenses.

- --------------------------------------------------------------------------------
Annual operating expenses
- --------------------------------------------------------------------------------
Management fee                                                 0.50%
Distribution and service (12b-1) fees                          0.25%
Other expenses                                                 0.14%
Total fund operating expenses(1)                               0.89%

The hypothetical example below shows what your expenses would be if you invested
$10,000 over the time frames indicated, assuming you reinvested all
distributions, that the average annual return was 5% and that your shares were
redeemed at the end of the time frame. The example is for comparison only, and
does not represent the fund's actual expenses and returns, either past or
future.

- --------------------------------------------------------------------------------
Expenses             Year 1      Year 3      Year 5       Year 10
- --------------------------------------------------------------------------------
                      $91         $284        $493        $1,096

FUND CODES

- ---------------------------
Ticker         --
CUSIP          --
Newspaper      --
Fund number    680

(1) The adviser has agreed to limit the fund's expenses excluding 12b-1 fees to
    0.70% of the fund's average daily net assets. The funds expenses shown
    above, excluding 12b-1 fees, are below 0.70%. If the expenses, exclusive of
    12b-1 fees, were to exceed 0.70% the total fund operating expenses would be
    limited to 0.95%.


                                                                               5
<PAGE>

Your account

- --------------------------------------------------------------------------------
UNDERSTANDING YOUR EXPENSES

The fund's expenses are to pay the operating costs of the fund. Some of these
costs include:
o portfolio management
o custody services
o transfer agent services

The Class P shares have a Rule 12b-1 plan that allows them to pay fees for the
sales distribution and service of these shares.

- --------------------------------------------------------------------------------
Class P
- --------------------------------------------------------------------------------
o No sales charges; all your money goes to work for you right away.

o Distribution and service (12b-1) fees  of 0.25%.

- --------------------------------------------------------------------------------
OPENING AN ACCOUNT

1  Read this prospectus carefully.

2  Determine how much you want to invest.

   o  minimum initial investments: $1,000

   o  Monthly Automatic Accumulation Plan (MAAP): $25 to open; you must invest
      at least $25 a month

3  Complete the account application, carefully following the instructions. You
   must submit additional documentation when opening trust, corporate or power
   of attorney accounts. You must notify your financial representative or
   Signature Services if this information changes. For more details, please
   contact your financial representative or call Signature Services at
   1-800-225-5291.

4  Make your initial investment using the table on the next page. You and your
   financial representative can initiate any purchase, exchange or sale of
   shares.


6 YOUR ACCOUNT
<PAGE>

- --------------------------------------------------------------------------------
Buying shares
- --------------------------------------------------------------------------------
           Opening an account                 Adding to an account
By check

[Clip Art] o  Make out a check for the        o  Make out a check for the
              investment amount, payable         investment amount payable
              to "John Hancock Signature         to "John Hancock Signature
              Services, Inc."                    Services, Inc."

           o  Deliver the check and your      o  Fill out the detachable
              completed application to           investment slip from an
              your financial                     account statement. If no
              representative, or mail            slip is available, include
              them to Signature Services         a note specifying the fund
              (address below).                   name, your share class,
                                                 your account number and the
                                                 name(s) in which the
                                                 account is registered.

                                              o  Deliver the check and your
                                                 investment slip or note to
                                                 your financial
                                                 representative, or mail
                                                 them to Signature Services
                                                 (address below).

By exchange

[Clip Art] o  Call your financial             o  Call your financial
              representative or Signature        representative or Signature
              Services to request an             Services to request an
              exchange.                          exchange.

By wire

[Clip Art] o  Deliver your completed          o  Instruct your bank to wire
              application to your                the amount of your
              financial representative,          investment to:
              or mail it to Signature             First Signature Bank & Trust
              Services.                           Account # 900000260
                                                  Routing # 211475000
           o  Obtain your account number
              by calling your financial       Specify the fund name, your
              representative or Signature     share class, your account
              Services.                       number and the name(s) in
                                              which the account is
           o  Instruct your bank to wire      registered. Your bank may
              the amount of your              charge a fee to wire funds.
              investment to:
               First Signature Bank & Trust
               Account # 900000260
               Routing # 211475000

           Specify the fund name, your
           choice of share class, the new
           account number and the name(s)
           in which the account is
           registered. Your bank may
           charge a fee to wire funds.

By phone

[Clip Art] See "By wire" and "By exchange."   o  Verify that your bank or
                                                 credit union is a member of
                                                 the Automated Clearing
                                                 House (ACH) system.

                                              o  Complete the "Invest By
                                                 Phone" and "Bank
                                                 Information" sections on
                                                 your account application.

                                              o  Call Signature Services to
                                                 verify that these features
                                                 are in place on your
                                                 account.

                                              o  Tell the Signature Services
                                                 representative the fund
                                                 name, your share class,
                                                 your account number, the
                                                 name(s) in which the
                                                 account is registered and
                                                 the amount of your
                                                 investment.

- -----------------------------------------

Address:
John Hancock Signature Services, Inc.
1 John Hancock Way, Suite 1000
Boston, MA 02217-1000

Phone Number: 1-800-225-5291

Or contact your financial representative
for instructions and assistance.

- -----------------------------------------

                       To open or add to an account using the Monthly Automatic
                       Accumulation Program, see "Additional investor services."


                                                                  YOUR ACCOUNT 7
<PAGE>

- --------------------------------------------------------------------------------
Selling shares
- --------------------------------------------------------------------------------
           Designed for                       To sell some or all of your shares
By letter

[Clip Art] o  Accounts of any type.           o  Write a letter of
                                                 instruction or complete a
           o  Sales of any amount.               stock power indicating the
                                                 fund name, your share
                                                 class, your account number,
                                                 the name(s) in which the
                                                 account is registered and
                                                 the dollar value or number
                                                 of shares you wish to sell.

                                              o  Include all signatures and
                                                 any additional documents
                                                 that may be required (see
                                                 next page).

                                              o  Mail the materials to
                                                 Signature Services.

                                              o  A check will be mailed to
                                                 the name(s) and address in
                                                 which the account is
                                                 registered, or otherwise
                                                 according to your letter of
                                                 instruction.

By phone

[Clip Art] o  Most accounts.                  o  For automated service 24
                                                 hours a day using your
           o  Sales of up to $100,000.           touch-tone phone, call the
                                                 EASI-Line at
                                                 1-800-338-8080.

                                              o  To place your order, call
                                                 your financial
                                                 representative or Signature
                                                 Services between 8 A.M. and
                                                 4 P.M. Eastern Time on most
                                                 business days.

By wire or electronic funds transfer (EFT)

[Clip Art] o  Requests by letter to sell      o  To verify that the
              any amount (accounts of any        telephone redemption
              type).                             privilege is in place on an
                                                 account, or to request the
           o  Requests by phone to sell          form to add it to an
              up to $100,000 (accounts           existing account, call
              with telephone redemption          Signature Services.
              privileges).
                                              o  Amounts of $1,000 or more
                                                 will be wired on the next
                                                 business day. A $4 fee will
                                                 be deducted from your
                                                 account.

                                              o  Amounts of less than $1,000
                                                 may be sent by EFT or by
                                                 check. Funds from EFT
                                                 transactions are generally
                                                 available by the second
                                                 business day. Your bank may
                                                 charge a fee for this
                                                 service.

By exchange

[Clip Art] o  Accounts of any type.           o  Obtain a current prospectus
                                                 for the fund into which you
           o  Sales of any amount.               are exchanging by calling
                                                 your financial
                                                 representative or Signature
                                                 Services.

                                              o  Call your financial
                                                 representative or Signature
                                                 Services to request an
                                                 exchange.


8 YOUR ACCOUNT
<PAGE>

Selling shares in writing In certain circumstances, you will need to make your
request to sell shares in writing. You may need to include additional items with
your request, unless they were previously provided to Signature Services and are
still accurate. These items are shown in the table below. You may also need to
include a signature guarantee, which protects you against fraudulent orders. You
will need a signature guarantee if:

o  your address of record has changed within the past 30 days

o  you are selling more than $100,000 worth of shares

o  you are requesting payment other than by a check mailed to the address of
   record and payable to the registered owner(s)

You will need to obtain your signature guarantee from a member of the Signature
Guarantee Medallion Program. Most brokers and securities dealers are members of
this program. A notary public CANNOT provide a signature guarantee.

- --------------------------------------------------------------------------------
Seller                                  Requirements for written requests
- --------------------------------------------------------------------------------
                                                                      [Clip Art]

Owners of individual, joint,            o  Letter of instruction.
sole proprietorship, UGMA/UTMA
(custodial accounts for                 o  On the letter, the
minors) or general partner                 signatures and titles of
accounts.                                  all persons authorized to
                                           sign for the account,
                                           exactly as the account is
                                           registered.

                                        o  Signature guarantee if
                                           applicable (see above).

Owners of corporate or                  o  Letter of instruction.
association accounts.
                                        o  Corporate resolution,
                                           certified within the past
                                           12 months, or a
                                           business/organization
                                           certification form.

                                        o  On the letter and the
                                           resolution, the signature
                                           of the person(s) authorized
                                           to sign for the account.

                                        o  Signature guarantee if
                                           applicable (see above).

Owners or trustees of trust             o  Letter of instruction.
accounts.
                                        o  On the letter, the
                                           signature(s) of the
                                           trustee(s).

                                        o  Copy of the trust document
                                           certified within the past
                                           12 months or a trust
                                           certification form.

                                        o  Signature guarantee if
                                           applicable (see above).

Joint tenancy shareholders              o  Letter of instruction
with rights of survivorship                signed by surviving tenant.
whose co-tenants are deceased.
                                        o  Copy of death certificate.

                                        o  Signature guarantee if
                                           applicable (see above).

Executors of shareholder                o  Letter of instruction
estates.                                   signed by executor.

                                        o  Copy of order appointing
                                           executor, certified within
                                           the past 12 months.

                                        o  Signature guarantee if
                                           applicable (see above).

Administrators, conservators,           o  Call 1-800-225-5291 for
guardians and other sellers or             instructions.
account types not listed
above.

- ------------------------------------------

Address:
John Hancock Signature Services, Inc.
1 John Hancock Way, Suite 1000
Boston, MA 02217-1000

Phone Number: 1-800-225-5291

Or contact your financial representative
for instructions and assistance.

- ------------------------------------------

                        To sell shares through a systematic withdrawal plan, see
                        "Additional investor services."


                                                                  YOUR ACCOUNT 9
<PAGE>

- --------------------------------------------------------------------------------
TRANSACTION POLICIES

Valuation of shares The net asset value per share (NAV) for the fund and class
is determined each business day at the close of regular trading on the New York
Stock Exchange (typically 4 P.M. Eastern Time). The fund uses market prices in
valuing portfolio securities, but may use fair-value estimates if reliable
market prices are unavailable. The fund may trade portfolio securities on U.S.
holidays and weekends, even though the fund's shares will not be priced on those
days. This may change the fund's NAV on days when you cannot buy or sell shares.

Buy and sell prices When you buy shares, you pay the NAV. When you sell shares,
you receive the NAV.

Execution of requests The fund is open on those days when the New York Stock
Exchange is open, typically Monday through Friday. Buy and sell requests are
executed at the next NAV to be calculated after Signature Services receives your
request in good order.

At times of peak activity, it may be difficult to place requests by phone.
During these times, consider using EASI-Line or sending your request in writing.

In unusual circumstances, the fund may temporarily suspend the processing of
sell requests, or may postpone payment of proceeds for up to three business days
or longer, as allowed by federal securities laws.

Telephone transactions For your protection, telephone requests may be recorded
in order to verify their accuracy. Also for your protection, telephone
transactions are not permitted on accounts whose names or addresses have changed
within the past 30 days. Proceeds from telephone transactions can only be mailed
to the address of record.

Certificated shares Most shares are electronically recorded. If you wish to have
certificates for your shares, please write to Signature Services. Certificated
shares can only be sold by returning the certificates to Signature Services,
along with a letter of instruction or a stock power and a signature guarantee.

Sales in advance of purchase payments When you place a request to sell shares
for which the purchase money has not yet been collected, the request will be
executed in a timely fashion, but the fund will not release the proceeds to you
until your purchase payment clears. This may take up to ten business days after
the purchase.

- --------------------------------------------------------------------------------
DIVIDENDS AND ACCOUNT POLICIES

Account statements In general, you will receive account statements as follows:

o  after every transaction (except a dividend reinvestment) that affects your
   account balance

o  after any changes of name or address of the registered owner(s)

o  in all other circumstances, every quarter

Every year you should also receive, if applicable, a Form 1099 tax information
statement, mailed by January 31.

Dividends The fund declares and pays any income dividends quarterly. Capital
gains dividends, if any, are distributed annually.

Dividend reinvestments Most investors have their dividends reinvested in
additional shares of the same fund and class. If you choose this option, or if
you do not indicate any choice, your dividends will be reinvested on the
dividend record date. Alternatively, you can choose to have a check for your
dividends mailed to you. However, if the check is not deliverable, your
dividends will be reinvested.

Taxability of dividends Dividends you receive from a fund, whether reinvested or
taken as cash, are generally considered taxable. Dividends from a fund's
short-term capital gains are taxable as ordinary income. Dividends from a fund's
long-term capital gains are taxable at a lower rate. Whether gains are
short-term or long-term depends on the fund's holding period. Some dividends
paid in January may be taxable as if they had been paid the previous December.

The Form 1099 that is mailed to you every January details your dividends and
their federal tax category, although you should verify your tax liability with
your tax professional.

Taxability of transactions Any time you sell shares, it is considered a taxable
event for you. Depending on the purchase price and the sale price of the shares
you sell, you may have a gain or a loss on the transaction. You are responsible
for any tax liabilities generated by your transactions.


10 YOUR ACCOUNT
<PAGE>

Small accounts (non-retirement only) If you draw down a non-retirement account
so that its total value is less than $1,000, you may be asked to purchase more
shares within 30 days. If you do not take action, your fund may close out your
account and mail you the proceeds. Alternatively, Signature Services may charge
you $10 a year to maintain your account. Your account will not be closed if its
drop in value is due to fund performance.

Year 2000 compliance The adviser and the fund's service providers are taking
steps to address any year 2000-related computer problems. However, there is some
risk that these problems could disrupt the issuers in which the fund invests,
the fund's operations or financial markets generally.

- --------------------------------------------------------------------------------
ADDITIONAL INVESTOR SERVICES

Monthly Automatic Accumulation Program (MAAP) MAAP lets you set up regular
investments from your paycheck or bank account to the John Hancock fund(s) of
your choice. You determine the frequency and amount of your investments, and you
can terminate your program at any time. To establish:

o  Complete the appropriate parts of your account application.

o  If you are using MAAP to open an account, make out a check ($25 minimum) for
   your first investment amount payable to "John Hancock Signature Services,
   Inc." Deliver your check and application to your financial representative or
   Signature Services.

Systematic withdrawal plan This plan may be used for routine bill payments or
periodic withdrawals from your account. To establish:

o  Make sure you have at least $5,000 worth of shares in your account.

o  Make sure you are not planning to invest more money in this account (buying
   shares during a period when you are also selling shares of the same fund is
   not advantageous to you).

o  Specify the payee(s). The payee may be yourself or any other party, and there
   is no limit to the number of payees you may have, as long as they are all on
   the same payment schedule.

o  Determine the schedule: monthly, quarterly, semi-annually, annually or in
   certain selected months.

o  Fill out the relevant part of the account application. To add a systematic
   withdrawal plan to an existing account, contact your financial representative
   or Signature Services.


                                                                 YOUR ACCOUNT 11
<PAGE>

Fund details

- --------------------------------------------------------------------------------
BUSINESS STRUCTURE

The diagram below shows the basic business structure used by the fund. The
funds' board of trustees oversees the fund's business activities and retains the
services of the various firms that carry out the fund's operations. The trustees
have the power to change this fund's investment goals without shareholder
approval.

Management fees For the fiscal year ended February 28, 1999, the fund paid the
investment adviser management fees at an annual rate of 0.50% of the fund's net
assets.

The management firm The fund is managed by John Hancock Advisers, Inc. Founded
in 1968, John Hancock Advisers is a wholly owned sudsidiary of John Hancock
Mutual Life Insurance Company and manages more than $30 billion in assets.

[The following information was represented as a flow chart in the printed
material.]

                                -----------------
                                  Shareholders
                                -----------------

  Distribution and
shareholder services

                -------------------------------------------------
                          Financial services firms and
                              their representatives

                      Advise current and prospective share-
                    holders on their fund investments, often
                  in the context of an overall financial plan.
                -------------------------------------------------

                -------------------------------------------------
                              Principal distributor

                            John Hancock Funds, Inc.

                     Markets the fund and distributes shares
                   through selling brokers, financial planners
                      and other financial representatives.
                -------------------------------------------------

             ------------------------------------------------------
                                 Transfer agent

                      John Hancock Signature Services, Inc.

                 Handles shareholder services, including record-
               keeping and statements, distribution of dividends
                    and processing of buy and sell requests.
             ------------------------------------------------------

                                                                        Asset
                                                                      management

                      ------------------------------------
                                   Subadviser

                             Independence Investment
                                Associates, Inc.
                                 53 State Street
                                Boston, MA 02109
                      ------------------------------------

                      ------------------------------------
                               Investment adviser

                           John Hancock Advisers, Inc.
                              101 Huntington Avenue
                              Boston, MA 02199-7603

                         Manages the funds' business and
                             investment activities.
                      ------------------------------------

                      ------------------------------------
                                    Custodian

                           Investors Bank & Trust Co.

                      Holds the funds' assets, settles all
                      portfolio trades and collects most of
                         the valuation data required for
                          calculating each fund's NAV.
                      ------------------------------------

                      ------------------------------------
                                    Trustees

                         Oversee the funds' activities.
                      ------------------------------------


12 FUND DETAILS
<PAGE>

- --------------------------------------------------------------------------------


For more information

- --------------------------------------------------------------------------------

Two documents are available that offer further information on Independence
Growth & Income Fund:

ANNUAL/SEMIANNUAL REPORT TO SHAREHOLDERS

Includes financial statements, a discussion of the market conditions and
investment strategies that significantly affected performance, as well as the
auditor's report (in annual report only).

STATEMENT OF ADDITIONAL INFORMATION (SAI)

The SAI contains more detailed information on all aspects of the fund. The
current annual report is included in the SAI.

A current SAI has been filed with the Securities and Exchange Commission and is
incorporated by reference into (is legally a part of) this prospectus.

To request a free copy of the current annual/semiannual report or the SAI,
please contact John Hancock:

By mail:

John Hancock Signature
Services, Inc.
1 John Hancock Way, Suite 1000
Boston, MA 02217-1000

By phone: 1-800-225-5291

By EASI-Line: 1-800-338-8080

By TDD: 1-800-544-6713

On the Internet: www.jhancock.com/funds

Or you may view or obtain these documents from the SEC:

In person: at the SEC's Public Reference Room in Washington, DC

By phone: 1-800-SEC-0330

By mail: Public Reference Section
Securities and Exchange Commission
Washington, DC 20549-6009
(duplicating fee required)

On the Internet: www.sec.gov

SEC number: 811-8852

                                               (C) 1999 John Hancock Funds, Inc.
                                                                     KGIPN 10/99


<PAGE>




                        INDEPENDENCE GROWTH & INCOME FUND

                                 Class P Shares
                       Statement of Additional Information

                                 October 1, 1999

This Statement of Additional Information provides information about Independence
Growth & Income  Fund  (the  "Fund")  in  addition  to the  information  that is
contained in the Fund's  Prospectus.  The Fund is a  diversified  series of John
Hancock Institutional Series Trust (the "Trust").

This Statement of Additional Information is not a prospectus.  It should be read
in  conjunction  with the  Prospectus,  a copy of which can be obtained  free of
charge by writing or telephoning:

                      John Hancock Signature Services, Inc.
                         1 John Hancock Way, Suite 1000
                              Boston MA 02217-1000
                                 1-800-225-5291

                                TABLE OF CONTENTS

                                                                            Page

Organization of the Fund..............................................         2
Investment Objective and Policies.....................................         2
Investment Restrictions...............................................         9
Those Responsible for Management......................................        11
Investment Advisory and Other Services................................        21
Distribution Contracts................................................        24
Net Asset Value.......................................................        25
Special Redemptions...................................................        25
Additional Services and Programs......................................        26
Description of the Fund's Shares......................................        26
Tax Status............................................................        28
Calculation of Performance............................................        32
Brokerage Allocation..................................................        33
Transfer Agent Services...............................................        35
Custody of Portfolio..................................................        35
Independent Auditors..................................................        36
Appendix A- Description of Investment Risk............................       A-1
Appendix B-Description of Bond Ratings................................       B-1
Financial Statements..................................................       F-1


                                       1
<PAGE>


ORGANIZATION OF THE FUND

The Fund is a series of the Trust,  an open-end  investment  management  company
organized as a Massachusetts  business trust under the laws of The  Commonwealth
of  Massachusetts.  Prior to October 1, 1999,  the Fund was called John  Hancock
Independence Diversified Core Equity Fund II.

John Hancock Advisers,  Inc. (the "Adviser") is the Fund's  investment  adviser.
The Adviser is an indirect  wholly-owned  subsidiary of John Hancock Mutual Life
Insurance Company (the "Life Company"),  a Massachusetts  life insurance company
chartered in 1862,  with national  headquarters  at John Hancock Place,  Boston,
Massachusetts. The Subadviser of the Fund is Independence Investment Associates,
Inc.  ("IIA")  referred to herein as the "Subadviser" and is an affiliate of the
Life Company.

INVESTMENT OBJECTIVE AND POLICIES

The following  information  supplements the discussion of the Fund's  investment
objective  and  policies as  discussed  in the  Prospectus.  Appendix A contains
further information describing investment risks. The investment objective of the
Fund is non-fundamental and may be changed without shareholder  approval.  There
is no assurance that the Fund will achieve its investment objective.

The Fund seeks above-average total return consisting of capital appreciation and
income.  The Fund emphasizes  investments in companies  offering  capital growth
and/or income  potential  over both the  intermediate  and long term. The Fund's
performance and risk profile  benchmark is the Standard & Poor's 500 Stock Index
(the  "S&P  500  Index")  which  is  comprised  of  500   industrial,   utility,
transportation  and financial  companies in the United States  markets.  Most of
these  companies  are listed on the New York Stock  Exchange  (the  "Exchange").
Companies  included in the S&P 500 Index  represent  about 75% of the Exchange's
market  capitalization and 30% of the Exchange's issuers. The S&P 500 Index is a
capitalization-weighted  index calculated on a total return basis with dividends
reinvested.

The Fund has adopted  certain  investment  restrictions  that are detailed under
"Investment Restrictions" in this Statement of Additional Information where they
are classified as fundamental or nonfundamental.  Those restrictions  designated
as  fundamental  may not be changed  without  shareholder  approval.  The Fund's
investment  objective,  investment  policies  and  nonfundamental  restrictions,
however, may be changed by a vote of the Trustees without shareholder  approval.
If there is a change in the Fund's  investment  objective,  shareholders  should
consider  whether the Fund remains an  appropriate  investment in light of their
then current financial position and needs.

For a further  description  of the Fund's  investment  objectives,  policies and
restrictions  see "Goal and Strategy" and "Main Risks" in the Fund's  Prospectus
and "Investment Restrictions" in this Statement of Additional Information.


                                       2
<PAGE>


Common stocks. The Fund may invest in common stocks. Common stocks are shares of
a corporation or other entity that entitle the holder to a pro rata share of the
profits  of  the  corporation,   if  any,  without  preference  over  any  other
shareholder  or  class  of  shareholders,  including  holders  of such  entity's
preferred  stock and other senior  equity.  Ownership  of common  stock  usually
carries with it the right to vote and, frequently,  an exclusive right to do so.
The Fund will  diversify  its  investments  in common  stocks of  companies in a
number of industry  groups without  concentrating  in any  particular  industry.
Common stocks have the potential to outperform  fixed-income securities over the
long term. Common stocks provide the most potential for growth, yet are the more
volatile of the two asset classes.

Debt securities. Debt securities in which the Fund may invest are subject to the
risk of an issuer's  inability to meet  principal  and interest  payments on the
obligations  (credit  risk) and may also be subject to price  volatility  due to
such  factors  as  interest   rate   sensitivity,   market   perception  of  the
creditworthiness  of the issuer and  general  market  liquidity  (market  risk).
Particular  debt  securities will be selected based upon credit risk analysis of
potential  issuers,  the  characteristics  of the security and the interest rate
sensitivity  of the various debt issues  available  with respect to a particular
issuer,  and  analysis  of  the  anticipated  volatility  and  liquidity  of the
particular debt instruments.

Preferred  stocks.  The Fund may invest in  preferred  stocks.  Preferred  stock
generally has a preference to dividends and, upon liquidation,  over an issuer's
common  stock  but  ranks  junior  to debt  securities  in an  issuer's  capital
structure.  Preferred  stock  generally  pays  dividends in cash (or  additional
shares of preferred  stock) at a defined rate but, unlike  interest  payments on
debt  securities,  preferred stock dividends are payable only if declared by the
issuer's  board of directors.  Dividends on preferred  stock may be  cumulative,
meaning  that,  in the  event  the  issuer  fails to make  one or more  dividend
payments on the preferred stock, no dividends may be paid on the issuer's common
stock until all unpaid preferred stock dividends have been paid. Preferred stock
also may be subject to optional or mandatory redemption provisions.

Investment  in  Foreign  Securities.  The Fund may invest in the  securities  of
foreign  issuers in the form of sponsored and  unsponsored  American  Depository
Receipts  ("ADRs") and U.S.  dollar-denominated  securities  of foreign  issuers
traded  on U.S.  exchanges.  ADRs  (sponsored  and  unsponsored)  are  receipts,
typically  issued  by  U.S.  banks,   which  evidence  ownership  of  underlying
securities issued by a foreign  corporation.  ADRs are publicly traded on a U.S.
stock  exchange or in the  over-the-counter  market.  An  investment  in foreign
securities  including  ADRs may be affected by changes in currency  rates and in
exchange control regulations.  Issuers of unsponsored ADRs are not contractually
obligated to disclose material information including financial  information,  in
the United States and,  therefore,  there may not be a correlation  between such
information and the market value of the unsponsored ADR.  Foreign  companies may
not be subject to accounting standards or government  supervision  comparable to
U.S.  companies,  and there is often less publicly  available  information about
their  operations.  Foreign  companies  may also be  affected  by  political  or
financial inability abroad.  These risk considerations may be intensified in the
case of  investments  in ADRs of foreign  companies that are located in emerging
market countries.  ADRs of companies located in these countries may have limited
marketability and may be subject to more abrupt or erratic price movements.

Repurchase Agreements.  In a repurchase agreement the Fund buys a security for a
relatively short period (usually not more than 7 days) subject to the obligation
to sell it back to the issuer at a fixed time and price plus  accrued  interest.
The Fund will enter into  repurchase  agreements  only with member  banks of the
Federal Reserve System and with "primary dealers" in U.S. Government securities.
The Adviser will continuously  monitor the  creditworthiness of the parties with
whom the Fund enters into repurchase agreements.


                                       3
<PAGE>


The Fund has  established a procedure  providing that the securities  serving as
collateral  for  each  repurchase  agreement  must be  delivered  to the  Fund's
custodian  either  physically or in book-entry form and that the collateral must
be marked to market  daily to ensure  that each  repurchase  agreement  is fully
collateralized  at all times.  In the event of  bankruptcy or other default by a
seller  of  a  repurchase  agreement,   the  Fund  could  experience  delays  in
liquidating the underlying  securities during the period in which the Fund seeks
to enforce its rights thereto,  possible subnormal levels of income,  decline in
value of the  underlying  securities  or lack of access to  income  during  this
period as well as the expense of enforcing its rights.

Reverse Repurchase  Agreements.  The Fund may also enter into reverse repurchase
agreements  which  involve the sale of U.S.  Government  securities  held in its
portfolio to a bank with an agreement that the Fund will buy back the securities
at a fixed  future  date at a fixed  price plus an agreed  amount of  "interest"
which may be reflected in the repurchase price.  Reverse  repurchase  agreements
are  considered  to be  borrowings by the Fund.  Reverse  repurchase  agreements
involve the risk that the market value of securities  purchased by the Fund with
proceeds  of the  transaction  may  decline  below the  repurchase  price of the
securities  sold by the Fund which it is obligated to repurchase.  The Fund will
also  continue to be subject to the risk of a decline in the market value of the
securities sold under the agreements  because it will reacquire those securities
upon effecting its repurchase. To minimize various risks associated with reverse
repurchase agreements,  the Fund will establish a separate account consisting of
liquid securities,  of any type or maturity,  in an amount at least equal to the
repurchase  prices of the securities (plus any accrued  interest  thereon) under
such agreements.  In addition,  the Fund will not enter into reverse  repurchase
agreements or borrow money,  except from banks  temporarily for extraordinary or
emergency  purposes (not for leveraging) in amounts not to exceed 33 1/3% of the
Fund's total assets  (including the amount  borrowed) taken at market value. The
Fund will not use  leverage  to attempt to  increase  income.  The Fund will not
purchase  securities while outstanding  borrowings exceed 5% of the Fund's total
assets.  The Fund  will  enter  into  reverse  repurchase  agreements  only with
federally  insured banks which are approved in advance as being  creditworthy by
the Trustees. Under the procedures established by the Trustees, the Adviser will
monitor the creditworthiness of the banks involved.

Restricted Securities.  The Fund may purchase securities that are not registered
("restricted  securities")  under  the  Securities  Act of  1933  ("1933  Act"),
including  commercial  paper  issued in reliance on Section 4(2) of the 1933 Act
and securities offered and sold to "qualified  institutional  buyers" under Rule
144A  under the 1933  Act.  The Fund  will not  invest  more than 15% of its net
assets  in  illiquid  investments.  If  the  Trustees  determine,  based  upon a
continuing review of the trading markets for specific Section 4(2) paper or Rule
144A securities, that they are liquid, they will not be subject to the 15% limit
on illiquid  investments.  The Trustees may adopt guidelines and delegate to the
Adviser the daily  function of  determining  the  monitoring  and  liquidity  of
restricted securities.  The Trustees,  however, will retain sufficient oversight
and  be  ultimately  responsible  for  the  determinations.  The  Trustees  will
carefully monitor the Fund's  investments in these securities,  focusing on such
important  factors,  among others,  as valuation,  liquidity and availability of
information.  This  investment  practice could have the effect of increasing the
level of illiquidity in the Fund if qualified  institutional buyers become for a
time uninterested in purchasing these restricted securities.


                                       4
<PAGE>


Forward Commitment and When-Issued Securities.  The Fund may purchase securities
on a when-issued or forward commitment basis. "When-issued" refers to securities
whose terms are available and for which a market exists, but which have not been
issued.  The Fund will  engage  in  when-issued  transactions  with  respect  to
securities  purchased for its portfolio in order to obtain what is considered to
be an  advantageous  price  and  yield  at  the  time  of the  transaction.  For
when-issued  transactions,  no payment is made until  delivery  is due,  often a
month or more after the purchase. In a forward commitment transaction,  the Fund
contracts  to  purchase  securities  for a fixed  price at a future  date beyond
customary  settlement  time.  When the Fund  engages in forward  commitment  and
when-issued transactions, it relies on the seller to consummate the transaction.
The failure of the issuer or seller to consummate the  transaction may result in
the Fund losing the  opportunity  to obtain a price and yield  considered  to be
advantageous. The purchase of securities on a when-issued and forward commitment
basis also  involves a risk of loss if the value of the security to be purchased
declines prior to the settlement date.

On the date the Fund  enters  into an  agreement  to  purchase  securities  on a
when-issued or forward  commitment  basis, the Fund will segregate in a separate
account cash or liquid  securities,  of any type or maturity,  equal in value to
the  Fund's  commitment.  These  assets  will be  valued  daily at  market,  and
additional  cash or securities  will be segregated in a separate  account to the
extent  that the total  value of the assets in the  account  declines  below the
amount of the when-issued  commitments.  Alternatively,  the Fund may enter into
offsetting contracts for the forward sale of other securities that it owns.

Government  Securities.  The Fund may invest in government  securities.  Certain
U.S. Government securities,  including U.S. Treasury bills, notes and bonds, and
Government National Mortgage Association certificates ("GNMA"), are supported by
the full faith and credit of the United  States.  Certain other U.S.  Government
securities,  issued or  guaranteed by Federal  agencies or government  sponsored
enterprises,  are not  supported  by the full  faith and  credit  of the  United
States,  but may be supported by the right of the issuer to borrow from the U.S.
Treasury. These securities include obligations of the Federal Home Loan Mortgage
Corporation   ("FHLMC"),   and  obligations  supported  by  the  credit  of  the
instrumentality,  such as Federal National Mortgage  Association Bonds ("FNMA").
No  assurance  can be given  that the U.S.  Government  will  provide  financial
support to such Federal agencies, authorities,  instrumentalities and government
sponsored enterprises in the future.

Mortgage-Backed  Securities.  The  Fund  may  invest  in  mortgage  pass-through
certificates and  multiple-class  pass-through  securities,  such as real estate
mortgage investment conduits ("REMIC") pass-through certificates, collateralized
mortgage obligations ("CMOs") and stripped mortgage-backed  securities ("SMBS"),
and other types of  "Mortgage-Backed  Securities"  that may be  available in the
future.

Guaranteed Mortgage  Pass-Through  Securities.  Guaranteed mortgage pass-through
securities  represent  participation  interests in pools of residential mortgage
loans and are issued by U.S.  Governmental  or private lenders and guaranteed by
the U.S. Government or one of its agencies or  instrumentalities,  including but
not  limited  to the  GNMA,  the  FNMA  and the  FHLMC.  GNMA  certificates  are
guaranteed  by the full  faith and  credit  of the U.S.  Government  for  timely
payment of principal and interest on the  certificates.  FNMA  certificates  are
guaranteed by FNMA, a federally  chartered and privately owned corporation,  for
full and timely  payment of principal  and interest on the  certificates.  FHLMC
certificates  are guaranteed by FHLMC, a corporate  instrumentality  of the U.S.
Government,  for timely  payment of interest and the ultimate  collection of all
principal of the related mortgage loans.


                                       5
<PAGE>


Multiple-Class  Pass-Through Securities and Collateralized Mortgage Obligations.
CMOs and REMIC  pass-through  or  participation  certificates  may be issued by,
among others, U.S. Government agencies and  instrumentalities as well as private
lenders.  CMOs and REMIC  certificates  are issued in  multiple  classes and the
principal  of and interest on the  mortgage  assets may be  allocated  among the
several  classes of CMOs or REMIC  certificates  in various ways.  Each class of
CMOs or REMIC  certificates,  often  referred to as a "tranche,"  is issued at a
specific  adjustable  or fixed  interest rate and must be fully retired no later
than its final distribution date. Generally,  interest is paid or accrues on all
classes of CMOs or REMIC certificates on a monthly basis.

Typically,  CMOs are collateralized by GNMA, FNMA or FHLMC certificates but also
may be  collateralized  by other mortgage  assets such as whole loans or private
mortgage pass-through securities. Debt service on CMOs is provided from payments
of principal and interest on collateral of mortgaged assets and any reinvestment
income thereon.

A REMIC is a CMO that  qualifies  for special tax  treatment  under the Code and
invests in certain mortgages primarily secured by interests in real property and
other  permitted  investments.  Investors may purchase  "regular" and "residual"
interest  shares of beneficial  interest in REMIC trusts  although the Fund does
not intend to invest in residual interests.

Stripped  Mortgage-Backed   Securities.   SMBS  are  derivative   multiple-class
mortgage-backed  securities.  SMBS are usually  structured with two classes that
receive different proportions of interest and principal  distributions on a pool
of mortgage  assets.  A typical SMBS will have one class  receiving  some of the
interest and most of the  principal,  while the other class will receive most of
the interest and the remaining  principal.  In the most extreme case,  one class
will receive all of the  interest  (the  "interest  only" class) while the other
class will receive all of the principal (the "principal only" class). The yields
and market risk of interest only and principal only SMBS,  respectively,  may be
more volatile than those of other fixed income securities.  The staff of the SEC
considers privately issued SMBS to be illiquid.

Structured or Hybrid Notes. Funds that may invest in mortgage-backed  securities
may invest in "structured" or "hybrid" notes.  The  distinguishing  feature of a
structured  or hybrid  note is that the  amount  of  interest  and/or  principal
payable on the note is based on the  performance of a benchmark  asset or market
other  than  fixed-income  securities  or  interest  rates.  Examples  of  these
benchmarks include stock prices,  currency exchange rates and physical commodity
prices.  Investing in a structured  note allows the Fund to gain exposure to the
benchmark  market while fixing the maximum loss that the Fund may  experience in
the event that market does not perform as  expected.  Depending  on the terms of
the note,  the Fund may forego all or part of the  interest and  principal  that
would be payable on a  comparable  conventional  note;  the Fund's  loss  cannot
exceed this foregone interest and/or  principal.  An investment in structured or
hybrid notes involves risks similar to those associated with a direct investment
in the benchmark asset.


                                       6
<PAGE>


Risk  Factors   Associated  with   Mortgage-Backed   Securities.   Investing  in
Mortgage-Backed  Securities  involves certain risks,  including the failure of a
counter-party  to meet its  commitments,  adverse  interest rate changes and the
effects of  prepayments  on mortgage cash flows.  In addition,  investing in the
lowest  tranche of CMOs and REMIC  certificates  involves risks similar to those
associated   with   investing   in  equity   securities.   Further,   the  yield
characteristics of  Mortgage-Backed  Securities differ from those of traditional
fixed income securities.  The major differences  typically include more frequent
interest and principal payments (usually monthly), the adjustability of interest
rates,   and  the  possibility   that  prepayments  of  principal  may  be  made
substantially earlier than their final distribution dates.

Prepayment  rates are  influenced  by changes in  current  interest  rates and a
variety  of  economic,  geographic,  social  and  other  factors  and  cannot be
predicted with  certainty.  Both  adjustable  rate mortgage loans and fixed rate
mortgage  loans may be subject to a greater rate of principal  prepayments  in a
declining   interest  rate  environment  and  to  a  lesser  rate  of  principal
prepayments in an increasing  interest rate environment.  Under certain interest
rate and  prepayment  rate  scenarios,  the Fund may fail to  recoup  fully  its
investment in Mortgage-Backed  Securities notwithstanding any direct or indirect
governmental,  agency  or  other  guarantee.  When the  Fund  reinvests  amounts
representing payments and unscheduled prepayments of principal, it may receive a
rate of  interest  that is  lower  than  the rate on  existing  adjustable  rate
mortgage  pass-through  securities.   Thus,   Mortgage-Backed   Securities,  and
adjustable  rate mortgage  pass-through  securities in  particular,  may be less
effective than other types of U.S. Government  securities as a means of "locking
in" interest rates.

Conversely,  in a rising interest rate environment,  a declining prepayment rate
will  extend  the  average  life  of  many  Mortgage-Backed   Securities.   This
possibility is often referred to as extension  risk.  Extending the average life
of a Mortgage-Backed  Security  increases the risk of depreciation due to future
increases in market interest rates.

Risk  Associated With Specific Types of Derivative  Debt  Securities.  Different
types of derivative  debt  securities are subject to different  combinations  of
prepayment,   extension  and/or  interest  rate  risk.   Conventional   mortgage
pass-through  securities  and  sequential  pay CMOs are  subject to all of these
risks,  but are typically not leveraged.  Thus, the magnitude of exposure may be
less than for more leveraged Mortgage-Backed Securities.

The risk of early  prepayments is the primary risk associated with interest only
debt  securities  ("IOs"),   super  floaters,   other  leveraged  floating  rate
instruments and Mortgage-Backed  Securities  purchased at a premium to their par
value.  In some  instances,  early  prepayments may result in a complete loss of
investment in certain of these  securities.  The primary risks  associated  with
certain other derivative debt securities are the potential  extension of average
life and/or depreciation due to rising interest rates.

These  securities  include  floating rate securities  based on the Cost of Funds
Index ("COFI floaters"), other "lagging rate" floating rate securities, floating
rate securities that are subject to a maximum interest rate ("capped floaters"),
Mortgage-Backed  Securities purchased at a discount,  leveraged inverse floating
rate securities  ("inverse  floaters"),  principal only debt securities ("POs"),
certain residual or support tranches of CMOs and index amortizing  notes.  Index
amortizing  notes  are  not  Mortgage-Backed  Securities,  but  are  subject  to
extension  risk  resulting  from the issuer's  failure to exercise its option to
call or redeem the notes before their stated  maturity date.  Leveraged  inverse
IOs combine several elements of the Mortgage-Backed  Securities  described above
and thus present an especially intense combination of prepayment,  extension and
interest rate risks.


                                       7
<PAGE>


Planned  amortization  class ("PAC") and target  amortization  class ("TAC") CMO
bonds involve less exposure to prepayment, extension and interest rate risk than
other Mortgage-Backed  Securities,  provided that prepayment rates remain within
expected  prepayment  ranges or "collars." To the extent that  prepayment  rates
remain within these prepayment  ranges,  the residual or support tranches of PAC
and TAC CMOs  assume the extra  prepayment,  extension  and  interest  rate risk
associated with the underlying mortgage assets.

Other types of floating rate  derivative  debt  securities  present more complex
types of interest  rate risks.  For example,  range  floaters are subject to the
risk that the  coupon  will be  reduced to below  market  rates if a  designated
interest rate floats outside of a specified  interest rate band or collar.  Dual
index or yield curve  floaters  are subject to  depreciation  in the event of an
unfavorable change in the spread between two designated interest rates.  X-reset
floaters  have a coupon that  remains  fixed for more than one  accrual  period.
Thus, the type of risk involved in these securities depends on the terms of each
individual X-reset floater.

Ratings as  Investment  Criteria.  In  general,  the  ratings of Moody's and S&P
represent  the  opinions of these  agencies as to the quality of the  securities
which they rate. It should be emphasized however,  that ratings are relative and
subjective and are not absolute standards of quality. These ratings will be used
by the Funds as initial  criteria for the  selection  of  portfolio  securities.
Among the factors  which will be  considered  are the  long-term  ability of the
issuer to pay principal  and interest and general  economic  trends.  Appendix B
contains further information  concerning the rating of Moody's and S&P and their
significance.

Subsequent to its purchase by the Fund,  an issue of securities  may cease to be
rated or its rating may be reduced  below the minimum  required  for purchase by
the Fund. Neither of these events will require the sale of the securities by the
Fund,  but the Adviser will consider the event in its  determination  of whether
the Fund should continue to hold the securities.

Lending  of  Securities.  The Fund may lend  portfolio  securities  to  brokers,
dealers,  and financial  institutions if the loan is  collateralized  by cash or
U.S. Government securities according to applicable regulatory requirements.  The
Fund may reinvest any cash collateral in short-term  securities and money market
funds.  When the  Fund  lends  portfolio  securities,  there is a risk  that the
borrower may fail to return the  securities  involved in the  transaction.  As a
result, the Fund may incur a loss or, in the event of the borrower's bankruptcy,
the Fund may be delayed in or prevented from  liquidating  the  collateral.  The
Fund can lend portfolio  securities having a total value of 33 1/3% of its total
assets.

Short-Term Trading. Short-term trading means the purchase and subsequent sale of
a security  after it has been held for a relatively  brief  period of time.  The
Fund may engage in  short-term  trading in response to stock market  conditions,
changes in interest rates or other economic trends and developments,  or to take
advantage of yield disparities  between various fixed income securities in order
to realize capital gains or improve income. Short term turnover (100% or grater)
involves  correspondingly  greater  brokerage  expenses.  The  Fund's  portfolio
turnover rate is set forth in the table under the caption "Financial Highlights"
in the prospectus.


                                       8
<PAGE>


INVESTMENT RESTRICTIONS

Fundamental  Investment  Restrictions.   The  Fund  has  adopted  the  following
investment  restrictions  which may not be changed  without  the  approval  of a
majority  of the Fund's  outstanding  voting  securities  which,  as used in the
Prospectus  and this Statement of Additional  Information  means the approval by
the lesser of (1) the holders of 67% or more of the Fund's shares represented at
a meeting  if more than 50% of the  Fund's  outstanding  shares  are  present in
person or by proxy or (2) more than 50% of the outstanding shares.

The Fund may not:

1.       Issue senior  securities,  except as permitted by paragraphs 3, 6 and 7
         below.  For  purposes of this  restriction,  the  issuance of shares of
         beneficial  interest in  multiple  classes or series,  the  deferral of
         trustees'  fees,  the purchase or sale of options,  futures  contracts,
         forward   commitments  and  repurchase   agreements   entered  into  in
         accordance with the Fund's investment policies or within the meaning of
         paragraph 6 below, are not deemed to be senior securities.

2.       Purchase securities on margin or make short sales, or unless, by virtue
         of its ownership of other securities,  the Fund has the right to obtain
         securities equivalent in kind and amount to the securities sold and, if
         the right is  conditional,  the sale is made upon the same  conditions,
         except (i) in connection with arbitrage transactions,  (ii) for hedging
         the Fund's  exposure to an actual or anticipated  market decline in the
         value of its securities, (iii) to profit from an anticipated decline in
         the value of a security,  and (iv) obtaining such short-term credits as
         may  be  necessary   for  the  clearance  of  purchases  and  sales  of
         securities.

3.       Borrow money, except for the following extraordinary or emergency
         purposes: (i) from banks for temporary or short-term purposes or for
         the clearance of transactions in amounts not to exceed 33 1/3% of the
         value of the Fund's total assets (including the amount borrowed) taken
         at market value; (ii) in connection with the redemption of Fund shares
         or to finance failed settlements of portfolio trades without
         immediately liquidating portfolio securities or other assets; (iii) in
         order to fulfill commitments or plans to purchase additional securities
         pending the anticipated sale of other portfolio securities or assets;
         and (iv) The Fund may not borrow money for the purpose of leveraging
         the Fund's assets. For purposes of this investment restriction, the
         deferral of Trustees' fees and transactions in short sales, futures
         contracts, options on futures contracts, securities or indices and
         forward commitment transactions shall not constitute borrowing. .

4.       Act as an underwriter, except to the extent that in connection with the
         disposition  of portfolio  securities,  the Fund may be deemed to be an
         underwriter for purpose of the 1933 Act.

5.       Purchase  or sell real  estate  except that the Fund may (i) acquire or
         lease  office  space  for its own use,  (ii)  invest in  securities  of
         issuers that invest in real estate or interests  therein,  (iii) invest
         in  securities  that are secured by real estate or  interests  therein,
         (iv)  purchase and sell  mortgage-related  securities  and (v) hold and
         sell real estate  acquired by the Fund as a result of the  ownership of
         securities.

                                       9
<PAGE>


6.       Invest in commodities, except the Fund may purchase and sell options on
         securities,  securities  indices and  currency,  futures  contracts  on
         securities,  securities  indices  and  currency  and  options  on  such
         futures,   forward  foreign  currency   exchange   contracts,   forward
         commitments,  securities  index  put or call  warrants  and  repurchase
         agreements  entered  into in  accordance  with  the  Fund's  investment
         policies.

7.       Make loans,  except that the Fund (1) may lend portfolio  securities in
         accordance  with the Fund's  investment  policies  up to 33 1/3% of the
         Fund's total assets taken at market  value,  (2) enter into  repurchase
         agreements,  and (3)  purchase  all or a  portion  of an  issue of debt
         securities,  bank loan  participation  interests,  bank certificates of
         deposit, bankers' acceptances,  debentures or other securities, whether
         or  not  the  purchase  is  made  upon  the  original  issuance  of the
         securities.

8.       Purchase the securities of issuers  conducting their principal activity
         in the same industry if, immediately after such purchase,  the value of
         its  investments  in such industry would exceed 25% of its total assets
         taken at market value at the time of such  investment.  This limitation
         does not apply to investments in obligations of the U.S.
         Government or any of its agencies, instrumentalities or authorities.

9.       The Fund, with respect to 75% of total assets,  purchase  securities of
         an  issuer   (other   than  the  U.  S.   Government,   its   agencies,
         instrumentalities or authorities), if:

              (a) such purchase  would cause more than 5% of the Fund's total
                  assets taken at market value to be invested in the  securities
                  of such issuer; or

              (b) such  purchase  would at the time result in more than 10% of
                  the outstanding voting securities of such issuer being held by
                  the Fund.

         Non-Fundamental Investment Restrictions. The following investment
         restrictions are designated as non-fundamental and may be changed by
         the Trustees without shareholder approval.

The Fund may not:


1.       Participate  on a joint or  joint-and-several  basis in any  securities
         trading  account.  The "bunching" of orders for the sale or purchase of
         marketable   portfolio   securities   with  other  accounts  under  the
         management of the Adviser or any  Subadviser to save  commissions or to
         average prices among them is not deemed to result in a joint securities
         trading account.

2.       Purchase a security if, as a result, (i) more than 10% of the Fund's
         total assets would be invested in the securities of other investment
         companies, (ii) the Fund would hold more than 3% of the total
         outstanding voting securities of any one investment company, or (iii)
         more than 5% of the Fund's total assets would be invested in the
         securities of any one investment company. These limitations do not
         apply to (a) the investment of cash collateral, received by the Fund in
         connection with lending the Fund's portfolio securities, in the
         securities of open-end investment companies or (b) the purchase of
         shares of any investment company in connection with a merger,
         consolidation, reorganization or purchase of substantially all of the
         assets of another investment company. Subject to the above percentage
         limitations the Fund may, in connection with the John Hancock Group of
         Funds Deferred Compensation Plan for Independent Trustees/Directors,
         purchase securities of other investment companies within the John
         Hancock Group of Funds.

                                       10
<PAGE>



3.       Invest more than 15% of the net assets of the Fund, taken at market
         value, in illiquid securities.

4.       Purchase securities while outstanding borrowings exceed 5% of the
         Fund's total assets.

5.       Invest for the purpose of exercising control over or management of
         any company.

If a percentage  restriction on investment or utilization of assets as set forth
above  is  adhered  to at the time an  investment  is made,  a later  change  in
percentage  resulting  from changes in the values of a Fund's assets will not be
considered a violation of the restriction.

THOSE RESPONSIBLE FOR MANAGEMENT

The business of the Fund is managed by the  Trustees who elect  officers who are
responsible for the day-to-day  operations of the Fund and who execute  policies
formulated by the Trustees. Several of the officers and Trustees of the Fund are
also officers or directors of the Fund's Adviser and/or Subadviser,  or officers
and/or directors of the Fund's principal  distributor,  John Hancock Funds, Inc.
("John Hancock Funds").


                                       11
<PAGE>

<TABLE>
<CAPTION>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

Edward J. Boudreau, Jr. *                Trustee, Chairman and Chief            Chairman, Director and Chief
101 Huntington Avenue                    Executive Officer (1, 2)               Executive Officer, the Adviser;
Boston, MA  02199                                                               Chairman, Director and Chief
October 1944                                                                    Executive Officer, The Berkeley
                                                                                Financial Group, Inc. ("The
                                                                                Berkeley Group"); Chairman and
                                                                                Director, NM Capital Management,
                                                                                Inc. ("NM Capital"), John Hancock
                                                                                Advisers International Limited
                                                                                ("Advisers International") and
                                                                                Sovereign Asset Management
                                                                                Corporation ("SAMCorp"); Chairman
                                                                                and Chief Executive Officer, John
                                                                                Hancock Funds, Inc. ("John Hancock
                                                                                Funds"); Chairman, First Signature
                                                                                Bank and Trust Company; Director,
                                                                                John Hancock Insurance Agency, Inc.
                                                                                ("Insurance Agency, Inc."), John
                                                                                Hancock Advisers International
                                                                                (Ireland) Limited ("International
                                                                                Ireland"), John Hancock Capital
                                                                                Corporation and New England/Canada
                                                                                Business Council; Member,
                                                                                Investment Company Institute Board
                                                                                of Governors; Director, Asia
                                                                                Strategic Growth Fund, Inc.;
                                                                                Trustee, Museum of Science;
                                                                                Director, John Hancock Freedom
                                                                                Securities Corporation (until
                                                                                September 1996); Director, John
                                                                                Hancock Signature Services, Inc.
                                                                                ("Signature Services") (until
                                                                                January 1997).


- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.


                                       12
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

Stephen L. Brown*                        Trustee                                Chairman and Chief Executive
John Hancock Place                                                              Officer, John Hancock Mutual Life
P.O. Box 111                                                                    Insurance Company; Director, the
Boston, MA 02117                                                                Adviser, John Hancock Funds,
July 1937                                                                       Insurance Agency, John Hancock
                                                                                Subsidiaries, Inc., The Berkeley
                                                                                Group, Federal Reserve Bank of
                                                                                Boston, Signature Services (until
                                                                                January 1997;) Trustee, John
                                                                                Hancock Asset Management (until
                                                                                March 1997).


James F. Carlin                          Trustee                                Chairman and CEO, Carlin
233 West Central Street                                                         Consolidated, Inc.
Natick, MA 01760                                                                (management/investments); Director,
April 1940                                                                      Arbella Mutual (insurance), Health
                                                                                Plan Services, Inc., Massachusetts
                                                                                Health and Education Tax Exempt
                                                                                Trust, Flagship Healthcare, Inc.,
                                                                                Carlin Insurance Agency, Inc., West
                                                                                Insurance Agency, Inc. (until May
                                                                                1995), Uno Restaurant Corp.;
                                                                                Chairman, Massachusetts Board of
                                                                                Higher Education (until July 1999).




- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.


                                       13
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

William H. Cunningham                    Trustee                                Chancellor, University of Texas
601 Colorado Street                                                             System and former President of the
O'Henry Hall                                                                    University of Texas, Austin, Texas;
Austin, TX 78701                                                                Lee Hage and Joseph D. Jamail
January 1944                                                                    Regents Chair of Free Enterprise;
                                                                                Director, LaQuinta Motor Inns, Inc.
                                                                                (hotel management company)
                                                                                (1985-1998); Jefferson-Pilot
                                                                                Corporation (diversified life
                                                                                insurance company) and LBJ
                                                                                Foundation Board (education
                                                                                foundation); Advisory Director,
                                                                                Chase Bank (formerly Texas Commerce
                                                                                Bank - Austin).


Ronald R. Dion                           Trustee                                President and Chief Executive
250 Boylston Street                                                             Officer, R.M. Bradley &  Co., Inc.;
Boston, MA 02116                                                                Director, The New England Council
March 1946                                                                      and Massachusetts Roundtable;
                                                                                Trustee, North Shore Medical Center
                                                                                and a corporator of the Eastern
                                                                                Bank; Trustee, Emmanuel College.


Harold R. Hiser, Jr.                     Trustee                                Executive Vice President,
123 Highland Avenue                                                             Schering-Plough Corporation
Short Hill, NJ  07078                                                           (pharmaceuticals) (retired 1996);
October 1931                                                                    Director, ReCapital Corporation
                                                                                (reinsurance) (until 1995).



- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.



                                       14
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

Anne C. Hodsdon *                        Trustee and President (1,2)            President, Chief Operating Officer,
101 Huntington Avenue                                                           Chief Investment Officer and
Boston, MA  02199                                                               Director, the Adviser, The Berkeley
August 1953                                                                     Group; Executive Vice President and
                                                                                Director, John Hancock Funds;
                                                                                Director, Advisers International,
                                                                                Insurance Agency, Inc. and
                                                                                International Ireland; President and
                                                                                Director, SAMCorp. and NM Capital;
                                                                                Executive Vice President, the
                                                                                Adviser (until December 1994);
                                                                                Director, Signature Services (until
                                                                                January 1997).

Charles L. Ladner                        Trustee                                Senior Vice President and Chief
UGI Corporation                                                                 Financial Officer, UGI Corporation
P.O. Box 858                                                                    (Public Utility Holding Company)
Valley Forge, PA  19482                                                         (retired 1998); Vice President and
February 1938                                                                   Director for AmeriGas, Inc. (retired
                                                                                1998); Vice President of AmeriGas
                                                                                Partners, L.P. (until 1997);
                                                                                Director, EnergyNorth, Inc. (until
                                                                                1995).

- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.




                                       15
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

Leo E. Linbeck, Jr.                      Trustee                                Chairman, President, Chief Executive
3810 W. Alabama                                                                 Officer and Director, Linbeck
Houston, TX 77027                                                               Corporation (a holding company
August 1934                                                                     engaged in various phases of the
                                                                                construction industry and
                                                                                warehousing interests); Former
                                                                                Chairman, Federal Reserve Bank of
                                                                                Dallas (1992, 1993); Chairman of
                                                                                the Board, Linbeck Construction
                                                                                Corporation; Director, Duke Energy
                                                                                Corporation (a diversified energy
                                                                                company), Daniel Industries, Inc.
                                                                                (manufacturer of gas measuring
                                                                                products and energy related
                                                                                equipment), GeoQuest International
                                                                                Holdings, Inc. (a geophysical
                                                                                consulting firm); Director, Greater
                                                                                Houston Partnership.


Steven R. Pruchansky                     Trustee (1)                            Director and President, Mast
4327 Enterprise Avenue                                                          Holdings, Inc. (since 1991);
Naples, FL  34104                                                               Director, First Signature Bank &
August 1944                                                                     Trust Company (until August 1991);
                                                                                Director, Mast Realty Trust (until
                                                                                1994); President, Maxwell Building
                                                                                Corp. (until 1991).


- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.



                                       16
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

Richard S. Scipione *                    Trustee (1)                            General Counsel, John Hancock Mutual
John Hancock Place                                                              Life Insurance Company; Director,
P.O. Box 111                                                                    the Adviser, John Hancock Funds,
Boston, MA  02117                                                               Signator Investors, Inc., Insurance
August 1937                                                                     Agency, Inc., John Hancock
                                                                                Subsidiaries, Inc., SAMCorp. and NM
                                                                                Capital; The Berkeley Group; JH
                                                                                Networking Insurance Agency, Inc.;
                                                                                Signature Services (until January
                                                                                1997).

Norman H. Smith                          Trustee                                Lieutenant General, United States
243 Mt. Oriole Lane                                                             Marine Corps; Deputy Chief of Staff
Linden, VA  22642                                                               for Manpower and Reserve Affairs,
March 1933                                                                      Headquarters Marine Corps;
                                                                                Commanding General III Marine
                                                                                Expeditionary Force/3rd Marine
                                                                                Division (retired 1991).


- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.




                                       17
<PAGE>


                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

John P. Toolan                           Trustee                                Director, The Smith Barney Muni Bond
13 Chadwell Place                                                               Funds, The Smith Barney Tax-Free
Morristown, NJ  07960                                                           Money Funds, Inc., Vantage Money
September 1930                                                                  Market Funds (mutual funds), The
                                                                                Inefficient-Market Fund, Inc.
                                                                                (closed-end investment company) and
                                                                                Smith Barney Trust Company of
                                                                                Florida; Chairman, Smith Barney
                                                                                Trust Company (retired December,
                                                                                1991); Director, Smith Barney,
                                                                                Inc., Mutual Management Company and
                                                                                Smith Barney Advisers, Inc.
                                                                                (investment advisers) (retired
                                                                                1991); Senior Executive Vice
                                                                                President, Director and member of
                                                                                the Executive Committee, Smith
                                                                                Barney, Harris Upham & Co.,
                                                                                Incorporated (investment bankers)
                                                                                (until 1991).


Osbert M. Hood                           Senior Vice President and Chief        Senior Vice President , Chief
101 Huntington Avenue                    Financial Officer                      Financial Officer and Treasurer, the
Boston, MA  02199                                                               Adviser, the Berkeley Group and John
August 1952                                                                     Hancock Funds, Inc.; Vice President
                                                                                and Chief Financial Officer, John
                                                                                Hancock Mutual Life Insurance
                                                                                Company Retail Sector (until 1997).



- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.



                                       18
<PAGE>



                                         Positions Held                         Principal Occupation(s)
Name and Address                         With the Company                       During the Past Five Years
- ----------------                         ----------------                       --------------------------
      <S>                                      <C>                                         <C>

John A. Morin                            Vice President                         Vice President and Secretary, the
101 Huntington Avenue                                                           Adviser, The Berkeley Group,
Boston, MA  02199                                                               Signature Services, John Hancock
July 1950                                                                       Funds, NM Capital and SAMCorp.;
                                                                                Clerk, Insurance Agency, Inc.;
                                                                                Counsel, John Hancock Mutual Life
                                                                                Insurance Company (until February
                                                                                1996).


Susan S. Newton                          Vice President and Secretary           Vice President, the Adviser; John
101 Huntington Avenue                                                           Hancock Funds, Signature Services
Boston, MA  02199                                                               and The Berkeley Group.
March 1950

James J. Stokowski                       Vice President, Treasurer and Chief    Vice President, the Adviser.
101 Huntington Avenue                    Accounting Officer
Boston, MA  02199
November 1946


- -------------------
*   Trustee may be deemed to be an "interested person" of the Fund as defined in
    the Investment Company Act of 1940.
(1) Member of the Executive Committee. The Executive Committee may generally
    exercise most of the powers of the Board of Trustees.
(2) A member of the Investment Committee of the Adviser.
</TABLE>


                                       19
<PAGE>



The following table provides information regarding the compensation paid by the
Fund and the other investment companies in the John Hancock Fund Complex to the
Independent Trustees for their services. Messrs. Boudreau, Brown, Scipione and
Ms. Hodsdon, each a non-Independent Trustee, and each of the officers of the
Fund are interested persons of the Adviser, are compensated by the Adviser and
receive no compensation from the Fund for their services.

                            Aggregate               Total Compensation From the
                            Compensation            Fund and John Hancock Fund
Independent Trustees        From the Fund(1)        Complex to Trustees(2)
- --------------------        ----------------        ----------------------

James F. Carlin                      $  41                   $ 74,000
William H. Cunningham                   41                     74,000
Ronald R. Dion                          44                     18,500
Charles F. Fretz                         6                     57,121
Harold R. Hiser, Jr.                    39                     70,000
Charles L. Ladner                       42                     77,100
Leo E. Linbeck, Jr.                     41                     74,000
Patricia P. McCarter                     3                     43,696
Steven R. Pruchansky                    42                     77,100
Norman H. Smith                         44                     79,350
John P. Toolan                          42                     77,100
                             -------------                -----------
Total                               $ 385                    $721,967

(1) Compensation is for the fiscal year ended February 28, 1999.

(2) Total compensation paid by the John Hancock Funds Complex to the Independent
Trustees is as of December 31,  1998.  As of this date,  there were  sixty-seven
funds in the John Hancock Fund Complex,  with each of these Independent Trustees
serving on  thirty-two  funds.  Effective  October 1,  1998,  Mr.  Fretz and Ms.
McCarter resigned as Trustees of the Complex.

*As  of  December  31,  1998,  the  value  of  the  aggregate  accrued  deferred
compensation  amount from all funds in the John  Hancock  Funds  Complex for Mr.
Cunningham was $320,943,  Mr. Hiser was $115,084,  Ms. McCarter was $183,645 and
for Mr. Pruchansky was $75,016,  for Mr. Smith was $109,807,  for Mr. Toolan was
$403,714  under the John Hancock Group of Funds Deferred  Compensation  Plan for
Independent Trustees.

All of the  officers  listed  are  officers  or  employees  of  the  Adviser  or
affiliated  companies.  Some of the  Trustees  and officers may also be officers
and/or directors and/or Trustees of one or more of the other funds for which the
Adviser serves as investment adviser.

As of  July  13,  1999,  the  officers  and  Trustees  of the  Fund  as a  group
beneficially  owned less than 1% of the  outstanding  shares of the Fund.  As of
that date, the following shareholders of record beneficially owned 5% or more of
the outstanding shares of the Fund.

                                       20
<PAGE>


- --------------------------------------------------------------------------------
Name and Address of Shareholder           Percentage of Total Outstanding Shares

- --------------------------------------------------------------------------------
Invesco Retirement Plan Services                           18.26%
Att: Brad Echols
400 Colony Square Ste 2100
1201 Peachtree Street NE
Atlanta GA 30361-3500

- --------------------------------------------------------------------------------
Weil Gotshal & Manges Section                               7.79%
401K Savings & Investment Trust
767 Fifth Avenue
New York NY 10153-0023

- --------------------------------------------------------------------------------
Charles Schwabb Trust Company FBO                           5.22%
Gaylord Entertainment Co.
401K Savings Plan
1 Montgomery Street 7th Floor
San Francisco CA

- --------------------------------------------------------------------------------
Boeing Information Services, Inc.                           5.80%
7990 Boeing Court, M/S CV-42
Att: Dede O'Donnell 401K
Vienna VA 22182-3925

- --------------------------------------------------------------------------------

INVESTMENT ADVISORY AND OTHER SERVICES

The Adviser, located at 101 Huntington Avenue, Boston, Massachusetts 02199-7603,
was organized in 1968 and has more than $30 billion in assets under management
in its capacity as investment adviser to the Fund and the other mutual funds and
publicly traded investment companies in the John Hancock group of funds having a
combined total of over 1,400,000 shareholders. The Adviser is an affiliate of
the Life Company, one of the most recognized and respected financial
institutions in the nation. With total assets under management of more than $100
billion, the Life Company is one of the ten largest life insurance companies in
the United States, and carries a high rating with Standard & Poor's and A. M.
Best. Founded in 1862, the Life Company has been serving clients for over 130
years.

The Fund has entered  into an  investment  management  contract  (the  "Advisory
Agreement")  with the Adviser  which was  approved  by the Fund's  shareholders.
Pursuant to the Advisory Agreement,  the Adviser will: (a) furnish  continuously
an  investment  program  for the  Fund and  determine,  subject  to the  overall
supervision and review of the Trustees,  which investments  should be purchased,
held,  sold or exchanged,  and (b) provide  supervision  over all aspects of the
Fund's  operations  except those which are  delegated  to a custodian,  transfer
agent or other agent.

The Fund bears all costs of its  organization  and operation,  including but not
limited to  expenses  of  preparing,  printing  and  mailing  all  shareholders'
reports,  notices  prospectuses,  proxy  statements  and  reports to  regulatory
agencies;  expenses relating to the issuance,  registration and qualification of
shares;   government  fees;   interest   charges;   expenses  of  furnishing  to
shareholders  their account  statements;  taxes;  expenses of


                                       21
<PAGE>


redeeming shares; brokerage and other expenses connected with the execution of
portfolio securities transactions; expenses pursuant to the Fund's plan of
distribution; fees and expenses of custodians including those for keeping books
and accounts, maintaining a committed line of credit, and calculating the net
asset value of shares; fees and expenses of transfer agents and dividend
disbursing agents; legal, accounting, financial, management, tax and auditing
fees and expenses of the Fund (including an allocable portion of the cost of the
Adviser's employees rendering such services to the Fund the compensation and
expenses of Trustees who are not otherwise affiliated with the Trust, the
Adviser or any of their affiliates; expenses of Trustees' and shareholders'
meetings; trade association memberships; insurance premiums; and any
extraordinary expenses.

The  Adviser has  entered  into a  Sub-Advisory  Agreement  with IIA.  Under the
Sub-Advisory  Agreement,  the Subadviser,  subject to the review of the Trustees
and the overall  supervision  of the Adviser,  is  responsible  for managing the
investment  operations of the Fund and the composition of the Fund's  investment
portfolio and furnishing the Fund with advice and  recommendations  with respect
to  investments,  investment  policies and the purchase and sale of  securities.
IIA, located at 53 State Street,  Boston,  Massachusetts 02109, and organized in
1982, is a wholly owned indirect subsidiary of John Hancock Subsidiaries, Inc.

As compensation for its services under the Advisory Agreement, the Fund pays the
Adviser  monthly a fee based on a stated  percentage of the average of the daily
net assets of the Fund as follows:

Net Asset Value                                           Annual Rate
- ---------------                                           -----------

First $1 billion                                             0.50%
Amount over $1 billion                                       0.45%


The  advisory  fees paid by the Fund are greater  than those paid by most funds,
but they are comparable to those paid by many investment  companies with similar
investment objectives and policies. The Adviser (not the Fund) pays a portion of
its fee to the  Subadviser at the rate of 80% of the advisory fee payable on the
Fund's average daily net assets.

From time to time, the Adviser may reduce its fee or make other  arrangements to
limit the Fund's  expenses to a specified  percentage  of its average  daily net
assets.  The  Adviser  has agreed to limit Fund  expenses  (excluding  12b-1 and
transfer  agent fees) to 0.70% of the Fund's  average  daily net assets at least
until July 1, 2000. The Adviser  retains the right to reimpose a fee and recover
any other payments to the extent that, at the end of any fiscal year, the Fund's
annual expenses fall below this limit.

Securities  held by the  Fund may  also be held by  other  funds  or  investment
advisory clients for which the Adviser, the Subadviser or its affiliates provide
investment advice.  Because of different investment objectives or other factors,
a particular security may be bought for one or more funds or clients when one or
more other funds or clients are selling the same security.  If opportunities for
purchase or sale of securities by the Adviser or Subadviser  for the Fund or for
other funds or clients for which the Adviser or  Subadviser  renders  investment
advice arise for  consideration at or about the same time,  transactions in such
securities  will be made,  insofar  as  feasible,  for the  respective  funds or
clients  in a  manner  deemed  equitable  to all of  them.  To the  extent  that
transactions on behalf of more than one client of the Adviser, Subadviser or its
affiliates may increase the demand for securities  being purchased or the supply
of securities being sold, there may be an adverse effect on price.


                                       22
<PAGE>


Pursuant to its Advisory Agreement and Sub-Advisory  Agreement,  the Adviser and
Subadviser are not liable for any error of judgment or mistake of law or for any
loss suffered by the Fund in connection with the matters to which the respective
Agreements relate,  except a loss resulting from willful misfeasance,  bad faith
or gross  negligence on the part of the Adviser or Subadviser in the performance
of its duties or from reckless disregard of the obligations and duties under the
applicable Agreement.

Under  the  Sub-Advisory  Agreement  of the  Fund,  the  Fund  may use the  name
"Independence" or any name derived from or similar to it only for as long as the
Sub-Advisory  Agreement  is in effect.  When the  Sub-Advisory  Agreement  is no
longer in effect,  the Fund (to the extent that it  lawfully  can) will cease to
use any name indicating  that it is advised by or otherwise  connected with IIA.
In addition,  IIA or the Life Company may grant the  non-exclusive  right to use
the name  "Independence" or any similar name to any other corporation or entity,
including  but  not  limited  to any  investment  company  of  which  IIA or any
subsidiary  or  affiliate  thereof  or  any  successor  to the  business  of any
subsidiary or affiliate thereof shall be the investment adviser.

The  continuation  of the Advisory  Agreement,  Sub-Advisory  Agreement  and the
Distribution  Agreement  (discussed  below) was  approved by all  Trustees.  The
Advisory Agreement,  Sub-Advisory Agreement and the Distribution Agreement, will
continue in effect from year to year,  provided that its continuance is approved
annually  both  (i) by the  holders  of a  majority  of the  outstanding  voting
securities  of the  Trust  or by the  Trustees,  and (ii) by a  majority  of the
Trustees  who are not parties to the  Agreement or  "interested  persons" of any
such parties. Both Agreements may be terminated on 60 days written notice by any
party or by vote of a majority of the outstanding  voting securities of the Fund
and will terminate automatically if assigned.

Accounting and Legal Services Agreement.  The Trust, on behalf of the Fund, is a
party to an Accounting and Legal Services  Agreement with the Adviser.  Pursuant
to this agreement,  the Adviser  provides the Fund with certain tax,  accounting
and legal services.  For the fiscal year ended February 28, 1999, 1998 and 1997,
the Fund paid the  Adviser  $84,538,  $79,447  and  $48,011,  respectively,  for
services under this agreement.

In order to avoid conflicts with portfolio trades for the Fund, the Adviser, the
Subadviser  and  the  Fund  have  adopted  extensive  restrictions  on  personal
securities  trading by personnel of the Adviser and its affiliates.  In the case
of the Adviser,  some of these restrictions are:  pre-clearance for all personal
trades  and a ban on the  purchase  of  initial  public  offerings,  as  well as
contributions to specified charities of profits on securities held for less than
91  days.  IIA  has  adopted  similar   restrictions   which  may  differ  where
appropriate,  as long as they have the same  intent.  These  restrictions  are a
continuation  of the  basic  principle  that the  interests  of the Fund and its
shareholders come first.


                                       23
<PAGE>


DISTRIBUTION CONTRACTS

The Fund has a  Distribution  Agreement  with  John  Hancock  Funds.  Under  the
agreement,  John  Hancock  Funds is  obligated  to use its best  efforts to sell
shares of each class of the Fund.  Shares of the Fund are also sold by  selected
broker-dealers  (the "Selling  Brokers")  which have entered into selling agency
agreements  with John Hancock  Funds.  John Hancock Funds accepts orders for the
purchase  of the shares of the Fund which are  continually  offered at net asset
value next determined.

The Fund's Trustees  adopted a Distribution  Plan with respect to Class P shares
(the "Plan")  pursuant to Rule 12b-1 under the  Investment  Company Act of 1940.
Under the Plan, the Fund will pay  distribution and service fees at an aggregate
annual  rate of up to 0.25% of the  Fund's  Class P average  daily  net  assets.
Service fees will not exceed 0.25% of the Class P average daily net assets.  The
distribution  fees  will  be  used  to  reimburse  John  Hancock  Funds  for its
distribution  expenses,  including  but not  limited to: (i) initial and ongoing
sales  compensation to Selling Brokers and others  (including  affiliates of the
John  Hancock  Funds)  engaged in the sale of Fund  shares  and (ii)  marketing,
promotional and overhead  expenses  incurred in connection with the distribution
of Fund shares.  The service fees will be used to compensate Selling Brokers and
others for providing personal and account maintenance  services to shareholders.
In the event that John  Hancock  Funds is not fully  reimbursed  for payments or
expenses it incurs under the Class P Plan,  these  expenses  will not be carried
beyond twelve months from the date they were  incurred.  The Plans were approved
by the  Trustees,  including a majority of the Trustees  who are not  interested
persons of the Fund and who have no direct or indirect financial interest in the
operation of the Plans (the "Independent Trustees"),  by votes cast in person at
a meeting called for the purpose of voting on this Plan.

Pursuant to the Plan,  at least  quarterly,  John Hancock Funds provide the Fund
with a written  report of the amounts  expended  under the Plans and the purpose
for which these  expenditures  were made. The Trustees review these reports on a
quarterly basis to determine their continued appropriateness.

The  Plans  provide  that  they  will  continue  in  effect  only so long as its
continuance is approved at least annually by a majority of both the Trustees and
the Independent Trustees.  The Plans provide that they may be terminated without
penalty, (a) by a vote of a majority of the Independent Trustees,  (b) by a vote
of a majority of the Fund's  outstanding  shares of the applicable class upon 60
days' written notice to John Hancock Funds and (c) automatically in the event of
assignment.  The Plans further  provide that they may not be amended to increase
the maximum amount of the fees for the services  described  therein  without the
approval of a majority of the outstanding  shares of the class of the Fund which
has  voting  rights  with  respect  to that Plan.  Each plan  provides,  that no
material  amendment  to the Plans will be  effective  unless it is approved by a
majority vote of the Trustees and the Independent Trustees of the Fund.

Amounts paid to the John  Hancock  Funds by any class of shares of the Fund will
not be used to pay the  expenses  incurred  with  respect to any other  class of
shares of the Fund; provided, however, that expenses attributable to the Fund as
a whole will be  allocated,  to the extent  permitted  by law,  according to the
formula based upon gross sales dollars  and/or  average daily net assets of each
such class,  as may be  approved  from time to time by vote of a majority of the
Trustees.  From time to time,  the Fund may  participate  in joint  distribution
activities  with other Funds and the costs of those  activities will be borne by
each Fund in  proportion  to the relative  net asset value of the  participating
Fund.


                                       24
<PAGE>


NET ASSET VALUE

For purposes of calculating the net asset value (NAV) of the Fund's shares,  the
following procedures are utilized wherever applicable.

Debt investment  securities are valued on the basis of valuations furnished by a
principal  market- maker or a pricing service,  both of which generally  utilize
electronic  data  processing  techniques  to  determine  valuations  for  normal
institutional  size trading units of debt securities  without exclusive reliance
upon quoted prices.

Equity  securities  traded on a  principal  exchange or NASDAQ  National  Market
Issues  are  generally  valued  at last  sale  price  on the  day of  valuation.
Securities  in the  aforementioned  category for which no sales are reported and
other  securities  traded  over-the-counter  are  generally  valued  at the last
available bid price.

Short-term debt investments  which have a remaining  maturity of 60 days or less
are generally  valued at amortized  cost which  approximates  market  value.  If
market  quotations are not readily available or if in the opinion of the Adviser
any  quotation or price is not  representative  of true market  value,  the fair
value  of the  security  may be  determined  in good  faith in  accordance  with
procedures approved by the Trustees.

The NAV of each Fund and class is  determined  each business day at the close of
regular  trading on the New York Stock  Exchange  (typically  4:00 p.m.  Eastern
Time) by dividing a class's net assets by the number of its shares  outstanding.
On any day an international  market is closed and the New York Stock Exchange is
open,  any foreign  securities  will be valued at the prior day's close with the
current day's  exchange  rate.  Trading of foreign  securities may take place on
Saturdays and U.S.  business holidays on which the Fund's NAV is not calculated.
Consequently,  the  Fund's  portfolio  securities  may  trade and the NAV of the
Fund's  redeemable  securities  may be  significantly  affected  on days  when a
shareholder has no access to the Fund.

SPECIAL REDEMPTIONS

Although  it  would  not  normally  do so,  the  Fund  has the  right to pay the
redemption  price  of  shares  of the  Fund in  whole  or in  part in  portfolio
securities as prescribed by the Trustees.  When the shareholder  sells portfolio
securities  received in this fashion,  the  shareholders  will incur a brokerage
charge.  Any such  securities  would be valued for the  purposes  of making such
payment at the same value as used in determining net asset value.  The Fund has,
however,  elected to be governed by Rule 18f-1 under the Investment Company Act.
Under that rule,  the Fund must  redeem its shares for cash except to the extent
that the redemption  payments to any shareholder  during any 90-day period would
exceed  the  lesser of  $250,000  or 1% of the  Fund's  net  asset  value at the
beginning of such period.

                                       25
<PAGE>


ADDITIONAL SERVICES AND PROGRAMS

Systematic  Withdrawal Plan. The Fund permits the  establishment of a Systematic
Withdrawal  Plan.  Payments under this plan represent  proceeds arising from the
redemption  of Fund shares which may result in  realization  of gain or loss for
purposes  of  Federal,  state and  local  income  taxes.  The  maintenance  of a
Systematic  Withdrawal Plan  concurrently with purchases of additional shares of
the Fund could be  disadvantageous  to a  shareholder  because  redemptions  are
taxable events.  Therefore, a shareholder should not purchase shares at the same
time a Systematic  Withdrawal Plan is in effect.  The Fund reserves the right to
modify or discontinue  the Systematic  Withdrawal  Plan of any shareholder on 30
days'  prior  written  notice  to  such  shareholder,   or  to  discontinue  the
availability of such plan in the future.  The shareholder may terminate the plan
at any time by giving proper notice to Signature Services.

Monthly Automatic Accumulation Program ("MAAP"). The program is explained in the
Prospectus. The program, as it relates to automatic investment checks, is
subject to the following conditions:

The investments will be drawn on or about the day of the month indicated.

The privilege of making investments through the MAAP may be revoked by Signature
Services  without  prior  notice  if  any  investment  is  not  honored  by  the
shareholder's  bank.  The  bank  shall  be under no  obligation  to  notify  the
shareholder as to the non-payment of any checks.

The program may be discontinued by the shareholder  either by calling  Signature
Services or upon written notice to Signature Services which is received at least
five (5) business days prior to the order date of any investment.

DESCRIPTION OF THE FUND'S SHARES

The Trustees of the Trust are  responsible for the management and supervision of
the Fund.  The  Declaration  of Trust permits the Trustees to issue an unlimited
number of full and fractional shares of beneficial  interest of the Fund without
par value.  Under the  Declaration of Trust,  the Trustees have the authority to
create and classify shares of beneficial  interest in separate  series,  without
further action by  shareholders.  As of the date of this Statement of Additional
Information,  the  Trustees  have  authorized  shares  of the Fund and ten other
series.  Additional series may be added in the future.  The Declaration of Trust
also  authorizes the Trustees to classify and reclassify the shares of the Fund,
or any new series of the Trust,  into one or more  classes.  The  Trustees  have
authorized the issuance of Class P and Class I.

The shares of each class of the Fund represent an equal  proportionate  interest
in the assets  belonging  to that  class of the Fund.  Holders of Class P shares
have  exclusive  voting rights on matters  relating to the Class P  distribution
plan. The different classes of the Fund may bear different  expenses relating to
the cost of holding  shareholder  meetings  necessitated by the exclusive voting
rights  of any  class  of  shares.  When  issued,  shares  are  fully  paid  and
nonassessable.  In the event of  liquidation of the Fund,  shareholders  of each
class are entitled to share pro rata in the net assets of the Fund available for
distribution to  shareholders.  Shares of the Trust are freely  transferable and
have no preemptive, subscription or conversion rights.


                                       26
<PAGE>


In accordance with the provisions of the Declaration of Trust, the Trustees have
initially  determined that shares entitle their holders to one vote per share on
any matter on which such shares are entitled to vote. The Trustees may determine
in the future, without the vote or consent of shareholders,  that each dollar of
net asset value (number of shares owned times net asset value per share) will be
entitled to one vote on any matter on which such shares are entitled to vote.

Dividends paid by the Fund, if any, with respect to each class of shares will be
calculated in the same manner,  at the same time and on the same day and will be
in the same amount, except for differences resulting from the facts that (i) the
distribution  and service fees relating to Class P will be borne  exclusively by
that class, and (ii) each class of shares will bear any class expenses  properly
allocable  to that  class of  shares,  subject to the  conditions  the  Internal
Revenue  Service  imposes  with  respect  to  the   multiple-class   structures.
Similarly,  the net asset value per share may vary  depending  on which class of
shares  are  purchased.  No  interest  will  be  paid on  uncashed  dividend  or
redemption checks.

Unless  otherwise  required by the Investment  Company Act or the Declaration of
Trust,  the Fund has no intention of holding  annual  meetings of  shareholders.
Fund  shareholders  may  remove a Trustee  by the  affirmative  vote of at least
two-thirds of the Trust's  outstanding  shares and the Trustees  shall  promptly
call a meeting for such purpose when requested to do so in writing by the record
holders  of  not  less  than  10%  of  the  outstanding  shares  of  the  Trust.
Shareholders   may,  under  certain   circumstances,   communicate   with  other
shareholders in connection  with  requesting a special meeting of  shareholders.
However,  at any time that less than a majority of the Trustees  holding  office
were elected by the  shareholders,  the Trustees will call a special  meeting of
shareholders for the purpose of electing Trustees.

Under Massachusetts law,  shareholders of a Massachusetts  business trust could,
under certain  circumstances,  be held personally liable for acts or obligations
of the Fund.  However,  the  Fund's  Declaration  of Trust  contains  an express
disclaimer  of  shareholder  liability for acts,  obligations  or affairs of the
Fund.  The  Declaration  of Trust also provides for  indemnification  out of the
Fund's  assets for all losses and expenses of any  shareholder  held  personally
liable for reason of being or having  been a  shareholder.  The  Declaration  of
Trust  also  provides  that no  series  of the  Trust  shall be  liable  for the
liabilities  of any other series.  Furthermore,  no fund included in this Fund's
prospectus  shall be liable for the  liabilities of any other John Hancock Fund.
Liability is therefore  limited to  circumstances in which the Fund itself would
be unable to meet its  obligations,  and the  possibility of this  occurrence is
remote.

The Fund reserves the right to reject any  application  which conflicts with the
Fund's  internal  policies or the  policies of any  regulatory  authority.  John
Hancock Funds does not accept  starter,  credit card or third party checks.  All
checks  returned by the post office as  undeliverable  will be reinvested at net
asset  value in the fund or funds from which a  redemption  was made or dividend
paid. Information provided on the account application may be used by the Fund to
verify the accuracy of the  information or for  background or financial  history
purposes.  A joint account will be administered as a joint tenancy with right of
survivorship,  unless the joint owners notify Signature  Services of a different
intent.  A shareholder's  account is governed by the laws of The Commonwealth of
Massachusetts. For telephone transactions, the transfer agent will take measures
to verify the identity of the caller,  such as asking for name,  account number,
Social Security or other taxpayer ID number and other relevant  information.  If
appropriate  measures are taken,  the transfer agent is not  responsible for any
losses that may occur to any account due to an unauthorized telephone call. Also
for your protection  telephone  transactions are not permitted on accounts whose
names or addresses have changed within the past 30 days. Proceeds from telephone
transactions can only be mailed to the address of record.


                                       27
<PAGE>


Selling activities for the Fund may not take place outside the U.S. except with
U.S. military bases, APO addresses and U.S. diplomats. Brokers of record on
Non-U.S. investors' accounts with foreign mailing addresses are required to
certify that all sales activities have occurred, and in the future will occur,
only in the U.S. A foreign corporation may purchase shares of the Fund only if
it has a U.S. mailing address.

TAX STATUS

The Fund is treated as a separate  entity for accounting  and tax purposes,  has
qualified and elected to be treated as a "regulated  investment  company"  under
Subchapter M of the Internal Revenue Code of 1986, as amended (the "Code"),  and
intends to continue to qualify for each taxable  year.  As such and by complying
with the applicable  provisions of the Code regarding the sources of its income,
the timing of its distributions and the  diversification of its assets, the Fund
will not be subject to Federal income tax on its taxable  income  (including net
realized  capital gains) which is distributed to shareholders in accordance with
the timing requirements of the Code.

The Fund will be subject  to a 4%  nondeductible  Federal  excise tax on certain
amounts not distributed (and not treated as having been distributed) on a timely
basis in accordance  with annual  minimum  distribution  requirements.  The Fund
intends under normal  circumstances  to seek to avoid or minimize  liability for
such tax by satisfying such distribution requirements.

Distribution from the Fund's current or accumulated earnings and profits ("E&P")
will be taxable  under the Code for  investors  who are subject to tax. If these
distributions are paid from the Fund's "investment company taxable income," they
will be taxable as  ordinary  income;  and if they are paid from the Fund's "net
capital gain" they will be taxable as long-term  capital gain. (Net capital gain
is the excess (if any) of net long-term capital gain over net short-term capital
loss,  and investment  company  taxable income is all taxable income and capital
gains,  other than net capital gain,  after  reduction by deductible  expenses).
Some  distributions may be paid in January but may be taxable to shareholders as
if they had been received on December 31 of the previous year. The tax treatment
described above will apply without regard to whether  distributions are received
in cash or reinvested in additional shares of the Fund.

Distributions,  if any,  in excess of E&P will  constitute  a return of  capital
under the Code, which will first reduce an investor's  federal tax basis in Fund
shares and then, to the extent such basis is exceeded,  will generally give rise
to capital gains.  Shareholders who have chosen automatic  reinvestment of their
distributions  will have a federal tax basis in each share received  pursuant to
such a  reinvestment  equal to the amount of cash they would have  received  had
they  elected  to receive  the  distribution  in cash,  divided by the number of
shares received in the reinvestment.

The Fund may be  subject  to  withholding  and other  taxes  imposed  by foreign
countries  with  respect  to its  investments  in foreign  securities.  Some tax
conventions  between certain countries and the U.S. may reduce or eliminate such
taxes.  Because  more than 50% of the  Fund's  total  assets at the close of any
taxable year will not consist of stocks or securities  of foreign  corporations,
the Fund  will be  unable  to pass  such  taxes  through  to  shareholders,  who
consequently  will not include  any  portion of such taxes in their  incomes and
will not be entitled to any associated tax credits or deductions with respect to
such taxes.  The Fund will deduct the foreign taxes it pays in  determining  the
amount it has available for distribution to shareholders.


                                       28
<PAGE>


If the Fund invests in stock or ADRs representing  stock (including an option to
acquire  stock such as is inherent  in a  convertible  bond) in certain  foreign
corporations that receive at least 75% of their annual gross income from passive
sources  (such as interest,  dividends,  certain  rents and royalties or capital
gain) or hold at least 50% of their asset in investments  producing such passive
income ("passive foreign  investment  companies"),  the Fund could be subject to
Federal income tax and  additional  interest  charges on "excess  distributions"
received from such  companies or gain from the sale of stock in such  companies,
even if all income or gain actually  received by the Fund is timely  distributed
to its  shareholders.  The  Fund  would  not be  able  to  pass  through  to its
shareholders  any  credit  or  deduction  for  such a tax.  An  election  may be
available to ameliorate  these adverse tax  consequences,  but could require the
Fund to recognize taxable income or gain without the concurrent receipt of cash.
These investments could also result in the treatment of associated capital gains
as ordinary  income.  The Fund may limit  and/or  manage its holdings in passive
foreign  investment  companies or make an available election to minimize its tax
liability or maximize its return from these investments.

The amount of the Fund's net realized  capital gains,  if any, in any given year
will vary depending upon the Adviser's current  investment  strategy and whether
the  Adviser  believes  it to be in the best  interest of the Fund to dispose of
portfolio  securities  that  will  generate  capital  gains.  At the  time of an
investor's  purchase of Fund shares,  a portion of the  purchase  price is often
attributable to realized or unrealized  appreciation in the Fund's  portfolio or
undistributed taxable income of the Fund. Consequently, subsequent distributions
on those shares from such appreciation or income may be taxable to such investor
even if the net  asset  value of the  investor's  shares  is, as a result of the
distributions,  reduced  below  the  investor's  cost for such  shares,  and the
distributions in reality represent a return of a portion of the purchase price.

Upon a  redemption  or other  disposition  of shares of the Fund  (including  by
exercise of the exchange  privilege)in  a transaction  that is treated as a sale
for tax purposes,  a shareholder will ordinarily  realize a taxable gain or loss
depending  upon the  amount  of the  proceeds  and the  investor's  basis in his
shares.  Such gain or loss will be treated as capital gain or loss if the shares
are capital assets in the shareholder's hands. A sales charge paid in purchasing
shares of the Fund cannot be taken into account for purposes of determining gain
or loss on the  redemption or exchange of such shares within 90 days after their
purchase  to the extent  shares of the Fund or  another  John  Hancock  fund are
subsequently  acquired  without  payment  of a  sales  charge  pursuant  to  the
reinvestment or exchange  privilege.  This disregarded  charge will result in an
increase in the  shareholder's  tax basis in the shares  subsequently  acquired.
Also,  any loss  realized on a redemption  or exchange may be  disallowed to the
extent the shares  disposed of are replaced with other shares of the Fund within
a period of 61 days beginning 30 days before and ending 30 days after the shares
are disposed of, such as pursuant to automatic dividend reinvestments. In such a
case,  the  basis  of the  shares  acquired  will be  adjusted  to  reflect  the
disallowed loss.

Also,  any loss realized upon the redemption of shares with a tax holding period
of six months or less will be treated as a long-term  capital loss to the extent
of any amounts treated as distributions  of long-term  capital gain with respect
to such shares.  Shareholders  should  consult their own tax advisers  regarding
their particular circumstances to determine whether a disposition of Fund shares
is properly  treated as a sale for tax purposes,  as is assumed in the foregoing
discussion.


                                       29
<PAGE>


Although its present  intention is to  distribute,  at least  annually,  all net
capital  gain, if any, the Fund reserves the right to retain and reinvest all or
any portion of the excess,  as computed for Federal income tax purposes,  of net
long-term  capital gain over net  short-term  capital loss in any year. The Fund
will not in any event  distribute  net capital gain  realized in any year to the
extent that a capital  loss is carried  forward  from prior years  against  such
gain.  To  the  extent  such  excess  was  retained  and  not  exhausted  by the
carryforward  of prior  years'  capital  losses,  it would be subject to Federal
income tax in the hands of the Fund.  Upon proper  designation of this amount by
the Fund, each  shareholder  would be treated for Federal income tax purposes as
if the Fund had  distributed  to him on the last day of its taxable year his pro
rata share of such excess,  and he had paid his pro rata share of the taxes paid
by the  Fund  and  reinvested  the  remainder  in the  Fund.  Accordingly,  each
shareholder  would (a) include  his pro rata share of such  excess as  long-term
capital  gain in his  return for his  taxable  year in which the last day of the
Fund's taxable year falls,  (b) be entitled either to a tax credit on his return
for,  or to a refund of,  his pro rata share of the taxes paid by the Fund,  and
(c) be entitled to increase the adjusted tax basis for his shares in the Fund by
the difference  between his pro rata share of such excess and his pro rata share
of such taxes.

For Federal  income tax  purposes,  the Fund is permitted to carry forward a net
realized  capital loss in any year to offset net capital gains,  if any,  during
the eight years  following  the year of the loss. To the extent  subsequent  net
capital gains are offset by such losses, they would not result in Federal income
tax liability to the Fund and, as noted above,  would not be distributed as such
to shareholders. As of February 28, 1999, the Fund did not have any capital loss
carryforwards.

For purposes of the  dividends-received  deduction  available  to  corporations,
dividends  received by the Fund,  if any,  from U.S.  domestic  corporations  in
respect of the stock of such  corporations  held by the Fund,  for U.S.  Federal
income  tax  purposes,  for at least  46 days  (91  days in the case of  certain
preferred stock) during a prescribed period extending before and after each such
dividend and distributed  and properly  designated by the Fund may be treated as
qualifying  dividends.  Corporate  shareholders  must  meet the  holding  period
requirements  stated  above with  respect  to their  shares of the Fund for each
dividend in order to qualify for the  deduction  and, if they have any debt that
is deemed under the Code directly  attributable to such shares,  may be denied a
portion of the dividends  received  deduction.  The entire qualifying  dividend,
including the otherwise  deductible  amount,  will be included in  determining a
corporate shareholder's alternative minimum tax liability, if any. Additionally,
any  corporate   shareholder  should  consult  its  tax  adviser  regarding  the
possibility that its tax basis in its shares may be reduced,  for Federal income
tax purposes,  by reason of "extraordinary  dividends"  received with respect to
the shares,  and, to the extent  such basis  would be reduced  below zero,  that
current recognition of income would be required.

The Fund is required to accrue income on any debt securities that have more than
a de minimis amount of original issue discount (or debt securities acquired at a
market  discount,  if the Fund  elects  to  include  market  discount  in income
currently) prior to the receipt of the corresponding cash payments. However, the
Fund must distribute to shareholders for each taxable year  substantially all of
its net income and net capital gains,  including such income or gain, to qualify
as a regulated  investment company and avoid liability for any federal income or
excise tax. Therefore,  the Fund may have to dispose of its portfolio securities
under  disadvantageous  circumstances  to generate  cash, or may borrow cash, to
satisfy these distribution requirements.


                                       30
<PAGE>


A state  income (and  possibly  local income  and/or  intangible  property)  tax
exemption is generally available to the extent (if any) the Fund's distributions
are derived from interest on (or, in the case of intangible  property taxes, the
value of its assets is  attributable  to) certain U.S.  Government  obligations,
provided in some states that certain thresholds for holdings of such obligations
and/or reporting  requirements are satisfied.  The Fund will not seek to satisfy
any  threshold or reporting  requirements  that may apply in  particular  taxing
jurisdictions,   although  it  may  in  its  sole  discretion  provide  relevant
information to shareholders.

The Fund will be required to report to the Internal  Revenue Service (the "IRS")
all distributions to shareholders, as well as gross proceeds from the redemption
or exchange of Fund  shares,  except in the case of certain  exempt  recipients,
i.e., corporations and certain other investors distributions to which are exempt
from  the  information  reporting  provisions  of the  Code.  Under  the  backup
withholding provisions of Code Section 3406 and applicable Treasury regulations,
all  such  reportable  distributions  and  proceeds  may be  subject  to  backup
withholding  of federal  income tax at the rate of 31% in the case of non-exempt
shareholders   who  fail  to  furnish  the  Fund  with  their  correct  taxpayer
identification number and certain  certifications  required by the IRS or if the
IRS or a broker  notifies the Fund that the number  furnished by the shareholder
is  incorrect  or that the  shareholder  is subject to backup  withholding  as a
result of failure to report interest or dividend income.  The Fund may refuse to
accept an application that does not contain any required taxpayer identification
number or  certification  that the number  provided  is  correct.  If the backup
withholding  provisions are  applicable,  any such  distributions  and proceeds,
whether taken in cash or  reinvested  in shares,  will be reduced by the amounts
required  to be  withheld.  Any  amounts  withheld  may be  credited  against  a
shareholder's U.S. federal income tax liability.  Investors should consult their
tax advisers about the applicability of the backup withholding provisions.

Different tax treatment, including penalties on certain excess contributions and
deferrals, certain pre-retirement and post-retirement  distributions and certain
prohibited  transactions,  is  accorded  to  accounts  maintained  as  qualified
retirement  plans.  Shareholders  should  consult  their tax  advisers  for more
information.

The foregoing  discussion relates solely to Federal income tax law as applicable
to  U.S.  persons  (i.e.,   U.S.   citizens  and  residents  and  U.S.  domestic
corporations,  partnerships,  trusts or estates)  subject to tax under such law.
The discussion does not address special tax rules applicable to certain types of
investors,  such as  tax-exempt  entities,  insurance  companies  and  financial
institutions.  Dividends,  capital gain  distributions and ownership of or gains
realized on the  redemption  (including  an  exchange) of shares of the Fund may
also be subject to state and local taxes.  Shareholders should consult their own
tax advisers as to the Federal,  state or local tax consequences of ownership of
shares  of, and  receipt of  distributions  from,  the Fund in their  particular
circumstances.

Non-U.S.  investors  not engaged in a U.S.  trade or  business  with which their
investment in the Fund is effectively  connected will be subject to U.S. Federal
income  tax  treatment  that is  different  from  that  described  above.  These
investors may be subject to  non-resident  alien  withholding tax at the rate of
30% (or a lower  rate under an  applicable  tax  treaty)  on amounts  treated as
ordinary  dividends  from the Fund and,  unless an effective  IRS Form W-8, Form
W-8BEN,  or other authorized  withholding  certificate is on file, to 31% backup
withholding on certain other payments from the Fund.  Non-U.S.  investors should
consult  their tax advisers  regarding  such  treatment and the  application  of
foreign taxes to an investment in the Fund.


                                       31
<PAGE>


The Fund is not subject to  Massachusetts  corporate  excise or franchise taxes.
The Fund  anticipates  that,  provided  that the Fund  qualifies  as a regulated
investment  company  under the Code,  it will  also not be  required  to pay any
Massachusetts income tax.

CALCULATION OF PERFORMANCE

The average annual total return on Class I shares of the Fund for the 1 year
period ended February 28, 1999 was 18.98% Performance calculations for Class I
do not reflect distribution fees.

Class P shares did not commence  operations  until  October 1, 1999;  therefore,
there is no  average  total  return on Class P shares of the Fund for the 1 year
period ended February 28, 1999 and since inception.

Total return is computed by finding the average annual compounded rate of return
over the 1 year, 5 year and 10 year periods that would equate the initial amount
invested to the ending redeemable value according to the following formula:


                                n __________
                           T = \ / ERV/P - 1

Where:

P =       a hypothetical initial investment of $1,000.
T =       average annual total return.
n =       number of years.
ERV =     ending redeemable value of a hypothetical $1,000 investment made at
          the beginning of the 1 year, 5 year, and 10 year periods.

In addition to average  annual total returns,  the Fund may quote  unaveraged or
cumulative total returns  reflecting the simple change in value of an investment
over a stated period.  Cumulative total returns may be quoted as a percentage or
as a dollar amount, and may be calculated for a single  investment,  a series of
investments and/or a series of redemptions over any time period.

The Fund may advertise yield, where appropriate. The Fund's yield is computed by
dividing net investment  income per share  determined for a 30-day period by the
maximum  offering price per share (which  includes the full sales charge) on the
last day of the period, according to the following standard formula:

                                       32
<PAGE>


                                               6
                  Yield = 2 ( [ ( a - b ) + 1 ] - 1 )
                                  -----
                                   cd

Where:

         a =   dividends and interest earned during the period.
         b =   net expenses accrued during the period.
         c =   the average daily number of fund shares  outstanding  during
               the period that would be entitled to receive dividends.
         d =   the maximum offering price per share on the last day of the
               period (NAV where applicable).

From time to time,  in reports  and  promotional  literature,  the Fund's  total
return  will be compared  to indices of mutual  funds such as Lipper  Analytical
Services,  Inc.'s  "Lipper  -  Mutual  Fund  Performance  Analysis,"  a  monthly
publication  which tracks net assets,  total return and yield on mutual funds in
the United States. Ibottson and Associates, CDA Weisenberger and F.C. Towers are
also used for comparison purposes, as well as the Russell and Wilshire Indices.

Performance  rankings and ratings  reported  periodically in national  financial
publications  such as MONEY  Magazine,  FORBES,  BUSINESS  WEEK, THE WALL STREET
JOURNAL,  MICROPAL,  INC.,  MORNINGSTAR,  STANGER'S  and  BARRON'S  may  also be
utilized.  The Fund's promotional and sales literature may make reference to the
Fund's  "beta".  Beta is a reflection of the market  related risk of the Fund by
showing how responsive the Fund is to the market.

The performance of the Fund is not fixed or guaranteed.  Performance  quotations
should not be considered to be  representations  of  performance of the Fund for
any period in the  future.  The  performance  of the Fund is a function  of many
factors  including  its  earnings,  expenses and number of  outstanding  shares.
Fluctuating  market  conditions;  purchases,  sales and  maturities of portfolio
securities;  sales and redemptions of shares of beneficial interest; and changes
in  operating  expenses  are all examples of items that can increase or decrease
the Fund's performance.

BROKERAGE ALLOCATION

Decisions  concerning  the  purchase and sale of  portfolio  securities  and the
allocation  of  brokerage  commissions  are  made  by the  Adviser  pursuant  to
recommendations made by an investment  committee of the Adviser,  which consists
of officers  and  directors  of the  Adviser and  affiliates  and  officers  and
Trustees who are interested  persons of the Fund. Orders for purchases and sales
of securities are placed in a manner which, in the opinion of the Adviser,  will
offer the best  price and  market for the  execution  of each such  transaction.
Purchases from underwriters of portfolio  securities may include a commission or
commissions paid by the issuer,  and transactions with dealers serving as market
makers reflect a "spread".  Debt securities are generally  traded on a net basis
through  dealers  acting for their own account as principals and not as brokers;
no brokerage commissions are payable on these transactions.


                                       33
<PAGE>


In the U.S. Government  securities market,  securities are generally traded on a
"net" basis with  dealers  acting as principal  for their own account  without a
stated commission,  although the price of the security usually includes a profit
to the  dealer.  On  occasion,  certain  money  market  instruments  and  agency
securities  may be  purchased  directly  from  the  issuer,  in  which  case  no
commissions  or  premiums  are paid.  In other  countries,  both debt and equity
securities  are traded on exchanges at fixed  commission  rates.  Commissions on
foreign  transactions are generally higher than the negotiated  commission rates
available  in the U.S.  There  is  generally  less  government  supervision  and
regulation of foreign stock exchanges and broker-dealers than in the U.S.

The Fund's  primary  policy is to execute all  purchases  and sales of portfolio
instruments  at the  most  favorable  prices  consistent  with  best  execution,
considering all of the costs of the transaction including brokerage commissions.
This policy governs the selection of brokers and dealers and the market in which
a transaction is executed.  Consistent with the foregoing  primary  policy,  the
Rules of Fair Practice of the National  Association of Securities Dealers,  Inc.
and such other policies as the Trustees may determine,  the Adviser may consider
sales of shares of the Fund as a factor in the  selection of  broker-dealers  to
execute the Fund's portfolio transactions.

To the extent  consistent  with the foregoing,  the Fund will be governed in the
selection of brokers and dealers,  and the  negotiation of brokerage  commission
rates and dealer  spreads,  by the  reliability  and  quality  of the  services,
including primarily the availability and value of research information and, to a
lesser extent,  statistical  assistance furnished to the Adviser of the Fund and
their value and expected  contribution to the performance of the Fund. It is not
possible to place a dollar value on information and services to be received from
brokers and dealers,  since it is only  supplementary to the research efforts of
the  Adviser.  The receipt of  research  information  is not  expected to reduce
significantly  the  expenses  of  the  Adviser.  The  research  information  and
statistical  assistance  furnished  by brokers  and dealers may benefit the Life
Company or other advisory  clients of the Adviser,  and,  conversely,  brokerage
commissions and spreads paid by other advisory clients of the Adviser may result
in research information and statistical  assistance  beneficial to the Fund. The
Fund will not make  commitments  to  allocate  portfolio  transactions  upon any
prescribed basis. While the Adviser's officers will be primarily responsible for
the allocation of the Fund's brokerage business, their policies and practices in
this  regard  must be  consistent  with the  foregoing  and will at all times be
subject to review by the  Trustees.  For the fiscal  years ended on February 28,
1997,  1998 and 1999,  the Fund paid  negotiated  brokerage  commissions  in the
amount of $357,443, $617,705, and $559,111, respectively.

As permitted by Section 28(e) of the  Securities  Exchange Act of 1934, the Fund
may pay a broker which provides  brokerage and research  services to the Fund an
amount of disclosed  commission in excess of the commission which another broker
would have charged for effecting that transaction. This practice is subject to a
good faith  determination  by the Trustees that such commission is reasonable in
light of the services  provided  and to such  policies as the Trustees may adopt
from time to time. For the fiscal year ended February 28, 1999, the Fund did not
pay  commissions as  compensation  to any brokers for research  services such as
industry, economic and company reviews and evaluations of securities.

The  Adviser's  indirect  parent,  the  Life  Company,   is  the  indirect  sole
shareholder of Signator Investors, Inc., a broker-dealer (until January 1, 1999,
John Hancock Distributors,  Inc.) ("Signator" or "Affiliated Broker").  Pursuant
to procedures determined by the Trustees and consistent with the above policy of
obtaining best net results, the Fund may execute portfolio  transactions with or
through the Affiliated Broker.  During the fiscal years ended February 28, 1997,
1998 and 1999,  the Fund did not execute  any  portfolio  transactions  with the
Affiliated Broker.


                                       34
<PAGE>


Signator  may act as  broker  for the Fund on  exchange  transactions,  subject,
however,  to the general  policy of the Fund set forth above and the  procedures
adopted by the Trustees pursuant to the Investment Company Act. Commissions paid
to an  Affiliated  Broker  must be at least as  favorable  as  those  which  the
Trustees believe to be contemporaneously  charged by other brokers in connection
with comparable  transactions  involving  similar  securities being purchased or
sold. A transaction  would not be placed with an  Affiliated  Broker if the Fund
would have to pay a commission rate less favorable than the Affiliated  Broker's
contemporaneous  charges for comparable transactions for its other most favored,
but unaffiliated, customers, except for accounts for which the Affiliated Broker
acts as clearing  broker for another  brokerage  firm,  and any customers of the
Affiliated  Broker not comparable to the Fund as determined by a majority of the
Trustees who are not "interested  persons" (as defined in the Investment Company
Act) of the Fund,  the Adviser or the  Affiliated  Broker.  Because the Adviser,
which is affiliated with the Affiliated Broker, has, as an investment adviser to
the Fund,  the  obligation  to provide  investment  management  services,  which
include elements of research and related  investment  skills,  such research and
related  skills  will  not be  used by the  Affiliated  Broker  as a  basis  for
negotiating commissions at a rate higher than that determined in accordance with
the above criteria.

Other investment  advisory clients advised by the Adviser may also invest in the
same  securities as the Fund. When these clients buy or sell the same securities
at  substantially  the same time, the Adviser may average the transactions as to
price and  allocate the amount of  available  investments  in a manner which the
Adviser  believes to be equitable to each client,  including  the Fund.  In some
instances,  this  investment  procedure may  adversely  affect the price paid or
received by the Fund or the size of the position obtainable for it. On the other
hand, to the extent permitted by law, the Adviser may aggregate securities to be
sold or  purchased  for the Fund with  those to be sold or  purchased  for other
clients managed by it in order to obtain best execution.

TRANSFER AGENT SERVICES

John Hancock Signature  Services,  Inc., 1 John Hancock Way, Suite 1000, Boston,
MA 02217-1000,  a wholly owned indirect  subsidiary of the Life Company,  is the
transfer and dividend  paying  agent for the Fund.  The Fund will pay  Signature
Services an annual fee of 0.05% of the average daily net assets  attributable to
the Class P shares.

CUSTODY OF PORTFOLIO

Portfolio  securities  of the Fund are held  pursuant to a  custodian  agreement
between the Fund and  Investors  Bank & Trust  Company,  200  Clarendon  Street,
Boston,  Massachusetts  02116. Under the custodian  agreement,  Investors Bank &
Trust Company performs custody, portfolio and fund accounting services.

                                       35
<PAGE>



INDEPENDENT AUDITORS

The  independent  auditors of the Funds are  Deloitte & Touche LLP, 200 Berkeley
Street,  Boston,  Massachusetts 02116.  Deloitte & Touche LLP audits and renders
opinions on the Fund's annual financial statements and reviews the Fund's annual
Federal income tax returns.














                                       36
<PAGE>


APPENDIX A

MORE ABOUT RISK

A fund's risk profile is largely  defined by the fund's  primary  securities and
investment  practices.  You may find the most concise  description of the fund's
risk profile in the prospectus.

A fund is permitted to utilize -- within limits  established  by the trustees --
certain other  securities  and  investment  practices that have higher risks and
opportunities  associated  with them. To the extent that the Fund utilizes these
securities  or  practices,  its  overall  performance  may be  affected,  either
positively  or  negatively.  On the  following  pages are brief  definitions  of
certain  associated  risks with them with  examples  of related  securities  and
investment  practices  included in brackets.  See the "Investment  Objective and
Policies" and "Investment Restrictions" sections of this Statement of Additional
Information  for a  description  of this Fund's  investment  policies.  The Fund
follows certain policies that may reduce these risks.

As with any mutual fund, there is no guarantee that the Fund will earn income or
show a positive return over any period of time -- days, months or years.

TYPES OF INVESTMENT RISK

Correlation risk The risk that changes in the value of a hedging instrument will
not match those of the asset being hedged  (hedging is the use of one investment
to offset the effects of another investment).  Incomplete correlation can result
in  unanticipated  risks.  (e.g.,  short sales,  financial  futures and options;
securities and index options, currency contracts).

Credit risk The risk that the issuer of a  security,  or the  counterparty  to a
contract,  will  default  or  otherwise  become  unable  to  honor  a  financial
obligation.   (e.g.,  borrowing;   reverse  repurchase  agreements,   repurchase
agreements,  securities  lending,   non-investment-grade  securities,  financial
futures and options; securities and index options).

Currency risk The risk that  fluctuations in the exchange rates between the U.S.
dollar and foreign  currencies  may  negatively  affect an  investment.  Adverse
changes in  exchange  rates may erode or reverse  any gains  produced by foreign
currency  denominated  investments  and may widen  any  losses.  (e.g.,  foreign
equities,  financial futures and options; securities and index options, currency
contracts).

Information  risk The risk that key  information  about a security  or market is
inaccurate  or  unavailable.  (e.g.,  non-investment-grade  securities,  foreign
equities).


                                      A-1
<PAGE>


Interest rate risk The risk of market losses attributable to changes in interest
rates. With fixed-rate  securities,  a rise in interest rates typically causes a
fall in values, while a fall in rates typically causes a rise in values.  (e.g.,
non-investment-grade  securities,  financial futures and options; securities and
index options).

Leverage risk  Associated  with securities or practices (such as borrowing) that
multiply  small index or market  movements  into large changes in value.  (e.g.,
borrowing;  reverse repurchase  agreements,  when-issued  securities and forward
commitments).

o    Hedged  When a  derivative  (a  security  whose  value is based on  another
     security or index) is used as a hedge against an opposite position that the
     fund  also  holds,   any  loss  generated  by  the  derivative   should  be
     substantially  offset by gains on the hedged  investment,  and vice  versa.
     While  hedging  can  reduce  or  eliminate  losses,  it can also  reduce or
     eliminate  gains.  (e.g.,  short  sales,   financial  futures  and  options
     securities and index options; currency contracts).

o    Speculative  To the extent that a  derivative  is not used as a hedge,  the
     fund is directly exposed to the risks of that  derivative.  Gains or losses
     from  speculative  positions in a derivative may be  substantially  greater
     than the derivative's original cost. (e.g., short sales,  financial futures
     and options securities and index options; currency contracts).

o    Liquidity  risk  The risk  that  certain  securities  may be  difficult  or
     impossible  to sell at the time and the price that the seller  would  like.
     The seller may have to lower the price,  sell other  securities  instead or
     forego an investment opportunity, any of which could have a negative effect
     on fund management or performance. (e.g.,  non-investment-grand securities,
     short sales,  restricted  and illiquid  securities,  financial  futures and
     options securities and index options; currency contracts).

Management risk The risk that a strategy used by a fund's management may fail to
produce the intended result. Common to all mutual funds.

Market risk The risk that the market  value of a security  may move up and down,
sometimes rapidly and unpredictably.  These fluctuations may cause a security to
be worth less than the price  originally  paid for it, or less than it was worth
at an earlier time. Market risk may affect a single issuer, industry,  sector of
the  economy  or the  market as a whole.  Common to all stocks and bonds and the
mutual  funds that  invest in them.  (e.g.,  short  sales,  short-term  trading,
when-issued securities and forward commitments, non-investment-grade securities,
foreign equities,  financial  futures and options;  securities and index options
restricted and illiquid securities).


                                      A-2
<PAGE>


Natural event risk The risk of losses  attributable to natural  disasters,  crop
failures and similar events. (e.g., foreign equities).

Opportunity  risk The risk of missing out on an investment  opportunity  because
the assets  necessary to take  advantage of it are tied up in less  advantageous
investments. (e.g., short sales, when-issued securities and forward commitments;
financial   futures  and  options;   securities  and  index  options,   currency
contracts).

Political  risk The risk of  losses  attributable  to  government  or  political
actions,  from  changes in tax or trade  statutes to  governmental  collapse and
war.(e.g., foreign equities).

Valuation  risk The risk that a fund has valued  certain of its  securities at a
higher price than it can sell them for. (e.g.,  non-investment-grade securities,
restricted and illiquid securities).











                                      A-3

<PAGE>



APPENDIX B

Moody's describes its lower ratings for corporate bonds as follows:

Bonds which are rated Baa are considered as medium grade obligations, i.e., they
are neither highly protected nor poorly secured. Interest payments and principal
security appear adequate for the present but certain protective  elements may be
lacking or may be  characteristically  unreliable over any great length of time.
Such  bonds  lack  outstanding  investment  characteristics  and  in  fact  have
speculative characteristics as well.

Bonds which are rated Ba are judged to have speculative  elements;  their future
cannot be  considered  as well  assured.  Often the  protection  of interest and
principal  payments may be very moderate and thereby not well safeguarded during
both good and bad times over the future.  Uncertainty of position  characterizes
bonds in this class.

Bonds  which  are  rated  B  generally  lack  characteristics  of the  desirable
investment.  Assurance of interest and principal  payments or of  maintenance of
other terms of the contract over any long period of time may be small.

Bonds which are rated Caa are of poor standing. Such issues may be in default or
there may be present elements of danger with respect to principal or interest.

Bonds which are rated Ca represented obligations which are speculative in a high
degree. Such issues are often in default or have other marked shortcomings.

Bonds which are rated C are the lowest  rated class of bonds and issues so rated
can be regarded as having  extremely  poor  prospects of ever attaining any real
investment standing.

S&P describes its lower ratings for corporate bonds as follows:

Debt rated BBB is regarded as having an adequate  capacity to pay  interest  and
repay principal.  Whereas it normally exhibits adequate  protection  parameters,
adverse economic conditions or changing circumstances are more likely to lead to
a  weakened  capacity  to pay  interest  and  repay  principal  for debt in this
category than in higher rated categories.

Debt  rated  BB,  B,  CCC,  or CC is  regarded,  on  balance,  as  predominantly
speculative  with  respect to the  issuer's  capacity to pay  interest and repay
principal in  accordance  with the terms of the  obligations.  BB indicates  the
lowest degree of  speculation  and CC the highest degree of  speculation.  While
such debt will likely have some quality and  protective  characteristics,  these
are  outweighed  by large  uncertainties  or major  risk  exposures  to  adverse
conditions.

Moody's describes its three highest ratings for commercial paper as follows:

Issuers rated P-1 (or related supporting  institutions) have a superior capacity
for repayment of short-term promissory obligations.  P-1 repayment capacity will
normally be  evidenced  by the  following  characteristics:  (1) leading  market
positions  in  well-established  industries;  (2) high  rates of return on funds
employed; (3) conservative  capitalization  structures with moderate reliance on
debt and ample asset  protections;  (4) broad  margins in  earnings  coverage of
fixed  financial  charges  and  high  internal  cash  generation;  and (5)  well
established  access to a range of  financial  markets  and  assured  sources  of
alternate liquidity.


                                      B-1
<PAGE>


Issuers rated P- (or related supporting institutions) have a strong capacity for
repayment of short-term promissory obligations.  This will normally be evidenced
by many of the  characteristics  cited  above but to a lesser  degree.  Earnings
trends and  coverage  ratios,  while sound,  will be more subject to  variation.
Capitalization characteristics, while still appropriate, may be more affected by
external conditions. Ample alternate liquidity is maintained.

Issuers rated P-3 (or supporting  institutions)  have an acceptable  ability for
repayment   of  senior   short-term   obligations.   The   effect  of   industry
characteristics and market  compositions may be more pronounced.  Variability in
earnings and profitability may result in changes in the level of debt protection
measurements  and may  require  relatively  high  financial  leverage.  Adequate
alternate liquidity is maintained.

S&P describes its three highest ratings for commercial paper as follows:

A-1.  This  designation  indicated  that the degree of safety  regarding  timely
payment is very strong.

A-2.  Capacity  for timely  payment on issues with this  designation  is strong.
However,  the  relative  degree of safety is not as  overwhelming  as for issues
designated A-1.

A-3. Issues carrying this  designation  have a satisfactory  capacity for timely
payment.  They are, however,  somewhat more vulnerable to the adverse effects of
changes in circumstances than obligations carrying the higher designations.


                                      B-2
<PAGE>




FINANCIAL STATEMENTS

The financial statements listed below are included in the Fund's 1999 Annual
Report to Shareholders for the year ended February 28, 1999; (filed
electronically on April 28, 1999, accession number 0001010521-99-000200) and are
included in and incorporated by reference into Part B of the Registration
Statement for John Hancock Institutional Series Trust (file nos. 33-86102 and
811-8852).

John Hancock Institutional Series Trust
    John Hancock Independence Diversified Core Equity Fund II

    Statement of Assets and Liabilities as of February 28, 1999 (audited).
    Statement of Operations for the year ended February 28, 1999 (audited).
    Statement of Changes in Net Asset for the years ended February 28, 1999 and
    1998 (audited).
    Notes to Financial Statements.
    Financial Highlights for each of the years in the four year period ended
    February 28, 1999 (audited).
    Schedule of Investments as of February 28, 1999 (audited).
    Independent Auditors' Report.


                                      F-1

<PAGE>


                    JOHN HANCOCK INSTITUTIONAL SERIES TRUST

                                    PART C.

                               OTHER INFORMATION

Item. 23.   Exhibits:

The  exhibits to this  Registration  Statement  are listed in the Exhibit  Index
hereto and are incorporated herein by reference.

Item 24.   Persons Controlled by or under Common Control with Registrant.

No person is directly or indirectly  controlled by or under common  control with
Registrant.

Item. 25.  Indemnification.

Indemnification  provisions  relating to the  Registrant's  Trustees,  officers,
employees  and agents is set forth in Article  VII of the  Registrant's  By Laws
included as Exhibit 2 herein.

Under Section 12 of the Distribution Agreement,  John Hancock Funds, Inc. ("John
Hancock  Funds")  has  agreed to  indemnify  the  Registrant  and its  Trustees,
officers and controlling  persons against claims arising out of certain acts and
statements of John Hancock Funds.

Section 9(a) of the By-Laws of John Hancock Mutual Life Insurance  Company ("the
Insurance  Company")  provides,  in effect,  that the  Insurance  Company  will,
subject to  limitations  of law,  indemnify  each  present and former  director,
officer and employee of the Insurance Company who serves as a Trustee or officer
of the Registrant at the direction or request of the Insurance  Company  against
litigation  expenses and liabilities  incurred while acting as such, except that
such indemnification does not cover any expense or liability incurred or imposed
in  connection  with  any  matter  as to which  such  person  shall  be  finally
adjudicated  not to have acted in good faith in the  reasonable  belief that his
action was in the best interests of the Insurance Company. In addition,  no such
person  will be  indemnified  by the  Insurance  Company in respect of any final
adjudication  unless  such  settlement  shall have been  approved as in the best
interests of the Insurance Company either by vote of the Board of Directors at a
meeting  composed of directors who have no interest in the outcome of such vote,
or by vote of the policyholders. The Insurance Company may pay expenses incurred
in  defending an action or claim in advance of its final  disposition,  but only
upon receipt of an undertaking  by the person  indemnified to repay such payment
if he should be determined not to be entitled to indemnification.



                                      C-1

<PAGE>



          Article IX of the respective By-Laws of JH Funds, Inc. and the Adviser
          provides as follows:

          Section  9.01.  Indemnity:  Any person made or threatened to be made a
          party to any action,  suit or  proceeding,  whether  civil,  criminal,
          administrative or  investigative,  by reason of the fact that he is or
          was at any time since the  inception  of the  Corporation  a director,
          officer,  employee  or agent of the  Corporation,  or is or was at any
          time since the inception of the Corporation  serving at the request of
          the Corporation as a director,  officer,  employee or agent of another
          corporation,  partnership,  joint venture,  trust or other enterprise,
          shall be indemnified by the Corporation  against  expenses  (including
          attorney's  fees),  judgments,  fines and amounts  paid in  settlement
          actually  and  reasonably  incurred  by him in  connection  with  such
          action, suit or proceeding if he acted in good faith and the liability
          was not incurred by reason of gross  negligence or reckless  disregard
          of the duties  involved in the conduct of his office,  and expenses in
          connection  therewith may be advanced by the  Corporation,  all to the
          full extent authorized by law.

          Section 9.02. Not Exclusive;  Survival of Rights: The  indemnification
          provided by Section  9.01 shall not be deemed  exclusive  of any other
          right to which those  indemnified may be entitled,  and shall continue
          as to a person who has ceased to be a director,  officer,  employee or
          agent and shall  inure to the  benefit  of the  heirs,  executors  and
          administrators of such a person.


                                      C-2



<PAGE>



          Under the Investment  Management  Contracts of Registrant on behalf of
          each Fund. Each of the Registrant's  Investment  Management  Contracts
          (the  "Contracts")  provides  that the Adviser shall not be liable for
          any error of  judgment  or mistake of law or for any loss  suffered by
          the Fund in  connection  with matters to which the  Contract  relates,
          except a loss resulting from willful  misfeasance,  bad faith or gross
          negligence on the part of the Adviser in the performance of its duties
          or from reckless  disregard by it of its  obligations and duties under
          the  contract.  Any person,  even though also employed by the Adviser,
          who may be or become an  employee  of and paid a Fund shall be deemed,
          when  acting  within the scope of his  employment  by the Fund,  to be
          acting in such employment solely for the Fund and not as the Adviser's
          employee or agent.

          Under   the   Sub-Investment   Management   Contracts.   Each  of  the
          Sub-Investment  Management Contracts (the "Sub-Investment  Contracts")
          provides  that the  Sub-Adviser  shall not be liable  for any error of
          judgment or mistake of law or for any loss suffered by the Trust,  the
          Fund  or  the  Adviser  in  connection   with  matters  to  which  the
          Sub-Investment  Contract relates, except a loss resulting from willful
          misfeasance,  bad faith or gross negligence on the Sub-Adviser's  part
          in the  performance of its duties or from reckless  disregard by it of
          its obligations and duties under the contract. Any person, even though
          also employed by the Sub-Adviser,  who may be or become an employee of
          and paid by the Trust or the Fund shall be deemed,  when acting within
          the scope of his  employment by the Trust or the Fund, to be acting in
          such  employment  solely  for the  Trust  or the  Fund  and not as the
          Sub-Adviser's employee or agent.

          Insofar as indemnification for liabilities under the Securities Act of
          1933,  as amended  (the "1933  Act"),  may be  permitted  to Trustees,
          officers  and  controlling  persons  of  Registrant  pursuant  to  the
          foregoing provisions,  Registrant has been advised that in the opinion
          of the  Securities and Exchange  Commission  such  indemnification  is
          against  policy  as  expressed  in the  1933  Act and  is,  therefore,
          unenforceable.  In the event that a claim for indemnification  against
          such  liabilities  (other  than the payment by the  Registrant  in the
          successful  defense of any action,  suit or proceeding) is asserted by
          such Trustee,  officer or  controlling  person in connection  with the
          securities being registered, Registrant will, unless in the opinion of
          its  counsel  the matter has been  settled by  controlling  precedent,
          submit to a court of  appropriate  jurisdiction  the question  whether
          indemnification  by it is against  public  policy as  expressed in the
          1933 Act and will be governed by the final adjudication of such issue.

ITEM 26. BUSINESS AND OTHER CONNECTIONS OF INVESTMENT ADVISER

          For all of the information  required by this item reference is made to
          the Forms ADV, as amended,  filed under the Investment Advisers Act of
          1940 of the Registrant's  Adviser,  John Hancock Advisers,  Inc. (File
          No.  801-8124),  and  the  Registrant's   Sub-Advisers;   Independence
          Investment  Associates,  Inc.  (File No.  801-  18048),  John  Hancock
          Advisers International, Ltd. (File No. 801-294981) and Sovereign Asset


                                      C-3


<PAGE>



          Management  Corporation (File No. 801- 420231)  incorporated herein by
          reference.

ITEM 27. PRINCIPAL UNDERWRITERS

         (a) The Registrant's sole principal  underwriter is John Hancock Funds,
         Inc.,  which  also  acts as  principal  underwriter  for the  following
         investment  companies:   John  Hancock  Capital  Series,  John  Hancock
         Sovereign Bond Fund, John Hancock  Special  Equities Fund, John Hancock
         Strategic  Series,  John Hancock  Tax-Exempt  Series Fund, John Hancock
         World Fund, John Hancock  Investment Trust II, John Hancock  Investment
         Trust III, John Hancock Bond Trust,  John Hancock  California  Tax-Free
         Income Fund,  John Hancock Cash  Reserve,  Inc.,  John Hancock  Current
         Interest,  John Hancock Investment Trust, John Hancock Series Trust and
         John Hancock Tax-Free Bond Trust.

         (b) The  following  table  lists,  for each  director and officer of JH
         Funds, Inc., the information indicated.

<TABLE>
<CAPTION>
                                                Positions and                        Positions and
Name and Principal                              Offices with                         Offices with
 Business Address                                Underwriter                           Registrant
- ------------------                              -------------                        --------------
<S>                                             <C>                                  <C>
Edward J. Boudreau, Jr.                         Director, Chairman,                  Chairman and
101 Huntington Avenue                           and Chief Executive Officer          Chief Executive
Boston, Massachusetts                                                                Officer

Foster L. Aborn                                 Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

David F. D'Alessandro                           Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

William C. Fletcher                             Director                             None
53 State Street
Boston, Massachusetts

Robert H. Watts                                 Director, Executive                  None
101 Huntington Avenue                           Vice President and
Boston, Massachusetts                           Chief Compliance Officer

Anne C. Hodsdon                                 Director and                         President, Chief Investment
101 Huntington Avenue                           Executive Vice President             Officer and Chief
Boston, Massachusetts                                                                Operating Officer

Maureen R. Ford                                 Director                             None
101 Huntington Avenue
Boston, Massachusetts


                                      C-4


<PAGE>


                                               Positions and                        Positions and
Name and Principal                              Offices with                         Offices with
 Business Address                                Underwriter                           Registrant
- ------------------                              -------------                        --------------

James V. Bowhers                                President                            None
101 Huntington Avenue
Boston, Massachusetts

Osbert Hood                                     Senior Vice President,               Senior Vice President
101 Huntington Avenue                           Chief Financial Officer              and Chief Financial
Boston, Massachusetts                           and Treasurer                        Officer

David A. King                                   Director                             None
101 Huntington Avenue
Boston, Massachusetts

Peter Mawn                                      Senior Vice President                None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

John A. Morin                                   Vice President                       Vice President
101 Huntington Avenue                           and Secretary
Boston, Massachusetts

Susan S. Newton                                 Vice President                       Vice President and
101 Huntington Avenue                                                                Secretary
Boston, Massachusetts


                                      C-5


<PAGE>


                                                Positions and                        Positions and
Name and Principal                              Offices with                         Offices with
 Business Address                                Underwriter                           Registrant
- ------------------                              -------------                        --------------

J. William Benintende                           Vice President                       None
101 Huntington Avenue
Boston, Massachusetts

Gary Cronin                                     Vice President                       None
101 Huntington Avenue
Boston, Massachusetts

Kathleen M. Graveline                        Senior Vice President                   None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

Renee M. Humphrey                               Vice President                       None
101 Huntington Avenue
Boston, Massachusetts

Stephen L. Brown                                Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

Thomas E. Moloney                               Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

Jeanne M. Livermore                             Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

Richard S. Scipione                             Director                             Trustee
John Hancock Place
P.O. Box 111
Boston, Massachusetts


                                      C-6


<PAGE>


                                                Positions and                        Positions and
Name and Principal                              Offices with                         Offices with
 Business Address                                Underwriter                           Registrant
- ------------------                              -------------                        --------------

John M. DeCiccio                                Director                             None
John Hancock Place
P.O. Box 111
Boston, Massachusetts

Keith Hartstein                                Senior Vice President                 None
101 Huntington Avenue
Boston, Massachusetts

Karen Walsh                                    Vice President                        None
101 Huntington Avenue
Boston, Massachusetts

Kristine Pancare                               Vice President                        None
101 Huntington Avenue
Boston, Massachusetts

</TABLE>

     (c) None.

ITEM 30. LOCATION OF ACCOUNTS AND RECORDS

     Registrant  maintains  the records  required to be  maintained  by it under
     Rules 31a-1(a),  31a-1(b) and 31a-2(a) under the Investment  Company Act of
     1940 at its principal  executive offices at 101 Huntington Avenue,  Boston,
     Massachusetts  02199- 7603. Certain records,  including records relating to
     Registrant's  shareholders  and the physical  possession of its securities,
     may be maintained pursuant to Rule 31a-3 at the main office of Registrant's
     Transfer Agent or Custodian.

ITEM 31. MANAGEMENT SERVICES

     The Registrant is not a party to any  management-related  service contract,
     except as described in this Registration Statement.

ITEM 32. UNDERTAKINGS

     The Registrant undertakes:

     (a) not applicable;


                                      C-7


<PAGE>



     (b) to furnish each person to whom a prospectus is delivered with a copy of
     the  Registrant's  latest  annual report to  shareholders  upon request and
     without charge; and

     (c) if  requested  to do so by holders  of at least 10% of the  outstanding
     shares of the Registrant, to call and hold a meeting of shareholders of the
     Registrant  for the  purpose of voting  upon the  question  of removal of a
     trustee or trustees and to assist  shareholders in the  communication  with
     other shareholders.



























                                      C-8


<PAGE>


                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933 and the
Investment Company Act of 1940 the Registrant has duly cause the Registration
Statement to be signed on its behalf by the undersigned, thereto duly
authorized, in the City of Boston, and the Commonwealth of Massachusetts on the
29th day of July, 1999.

                                  JOHN HANCOCK INSTITUTIONAL SERIES TRUST

                                  By:                    *
                                           -------------------------------
                                           Edward J. Boudreau, Jr.
                                           Chairman

<TABLE>

     Pursuant  to  the   requirements   of  the  Securities  Act  of  1933,  the
Registration  has been signed below by the following  persons in the  capacities
and on the dates indicated.

<CAPTION>
             Signature                             Title                             Date
             ---------                             -----                             ----
<S>                                  <C>                                          <C>
              *                                   Chairman
- ---------------------------            (Principal Executive Officer)
Edward J. Boudreau, Jr.



/s/ James J. Stokowski                 Vice President, Treasurer and            July 29, 1999
- ---------------------------            Chief Accounting Officer
James J. Stokowski

              *
- ---------------------------                       Trustee
Stephen L. Brown

              *
- ---------------------------                       Trustee
James F. Carlin

              *
- ---------------------------                       Trustee
William H. Cunningham

              *
- ---------------------------                       Trustee
Ronald R. Dion


- ---------------------------                       Trustee
Anne C. Hodsdon


                                      C-9


<PAGE>



             Signature                             Title                             Date
             ---------                             -----                             ----

              *
- ---------------------------                       Trustee
Harold R. Hiser, Jr.

              *
- ---------------------------                       Trustee
Charles L. Ladner

              *
- ---------------------------                       Trustee
Leo E. Linbeck, Jr.

              *
- ---------------------------                       Trustee
Steven R. Pruchansky

              *
- ---------------------------                       Trustee
Richard S. Scipione

              *
- ---------------------------                       Trustee
Norman H. Smith

              *
- ---------------------------                       Trustee
John P. Toolan


*By:
/s/Susan S. Newton                                                                July 29, 1999
- ---------------------------
   Susan S. Newton
   Attorney-in-Fact under
   Powers of Attorney dated
   January 1, 1999 and March 17, 1999.

</TABLE>

                                      C-10


<PAGE>

                       JOHN HANCOCK INSTITUTIONAL SERIES
                       ---------------------------------
                                INDEX TO EXHIBITS
                                -----------------


99.(a)          Articles of Incorporation.  Declaration of Trust dated
                October 31, 1994.*

99.(a).1        Instrument Changing Names of Series of Shares of
                Trust, Increasing the Number of Trustees and Appointing
                Individuals to Fill the Vacancies, and Establishing
                New Series.**

99.(a).2        Instrument Increasing the Number of Trustees and Appointing
                Individual to Fill the Vacancy.****

99.(a).3        Instrument Changing Names of Series of Shares of the
                Trust dated December 3, 1997.******

99.(a).4        Abolition of John Hancock Global Fund dated
                February 26, 1999.*******

99.(a).5        Instrument changing Name of a Series of Shares of the Trust from
                John Hancock Multi-Sector Growth Fund to John Hancock Medium
                Capitalization Growth Fund dated April 27, 1999.#

99.(a).6        Amendment of Section 5.11 to establish the following Series:
                John Hancock Independence Diversified Core Equity Fund II, John
                Hancock Independence Medium Capitalization Fund, John Hancock
                Independence Balanced Fund, John Hancock Active Bond Fund, John
                Hancock Dividend Performers Fund, John Hancock International
                Equity Fund, John Hancock Medium Capitalization Growth Fund,
                John Hancock Small Capitalization Growth Fund, and John Hancock
                Small Capitalization Value Fund, each consisting of a single
                class of shares: John Hancock Core Growth Fund and John Hancock
                Core Value Fund, each consisting of Class A, Class B, Class C
                and Class I Shares (The "Existing Series") dated
                April 27, 1999.#

99.(a).7        Instrument designation of existing Class of Shares,
                establishment and Designation of New Class B, Class C and Class
                I Shares, Change of Names of two Series of Shares of Beneficial
                Interest of John Hancock Independence Growth Fund and John
                Hancock Independence Value Fund each a Series of John Hancock
                Institutional Trust.#

99.(a).8        Designation of Existing Class of Shares for Core Growth and Core
                Value and change of names of funds effective 7/1/99.+

99.(b)          By laws.  Amended and Restated By-Laws dated
                November 19, 1996.*****

99.(c)          Instruments Defining Rights of Securities Holders.  See exhibits
                99.(a) and 99.(b).

99.(d)          Investment Advisory Contracts.  Investment Management Contracts
                between John Hancock Advisers, Inc. and the Registrant on behalf
                of John Hancock Berkeley Bond Fund, John Hancock Berkeley Sector
                Opportunity Fund, John Hancock Independence Diversified Core
                Equity Fund II, John Hancock Berkeley Dividend Performers Fund,
                John Hancock Berkeley Global Bond Fund, John Hancock Berkeley
                Fundamental Value Fund, John Hancock Berkeley Overseas Growth
                Fund.*

99.(d).1        Sub-Investment Management Contracts among the
                Registrant on behalf of  John Hancock Independence
                Diversified Core Equity Fund II and John Hancock
                Independence Balanced Fund, John Hancock Advisers,
                Inc., and Independence Investment Associates, Inc.*

99.(d).2        Sub-Investment Management Contract among the Registrant
                on behalf of John Hancock Berkeley Dividend Performers
                Fund, John Hancock Advisers, Inc., and Sovereign Asset
                Management Corporation.*

99.(d).3        Sub-Investment Management Contact among the Registrant
                on behalf of John Hancock Berkeley Overseas Growth
                Fund, John Hancock Advisers, Inc., and John Hancock
                Advisers International, Ltd.*

                                      C-11
<PAGE>



99.(d).4        Sub-Investment Management Contract among the Registrant
                on behalf of John Hancock Berkeley Fundamental Value
                Fund, John Hancock Advisers, Inc., and NM Capital
                Management, Inc.*

99.(d).5        Investment Management Contracts between John Hancock
                Advisers, Inc. and the Registrant on behalf of John
                Hancock Independence Value Fund, John Hancock Independence
                Growth Fund, John Hancock Independence Balanced Fund, John
                Hancock Small Capitalization Equity Fund, and John Hancock
                Independence Medium Capitalization Fund.***

99.(d).6        Sub-Investment Management Contract among the Registrant on
                behalf of John Hancock Independence Value Fund, John Hancock
                Independence Medium Capitalization Fund, and John Hancock
                Independence Growth Fund, John Hancock Advisers, Inc., and
                Independence Investment Associates, Inc.***

99.(e)          Underwriting Contracts.  Distribution Agreement between the
                Registrant and John Hancock Funds, Inc. dated January 30, 1995.*

99.(e).1        Amendment to Distribution Agreement between the Registrant and
                John Hancock Funds, Inc. dated December 11, 1995.***

99.(e).2        Distribution Plans between the Registrant and John Hancock Funds
                for John Hancock Core Growth Fund Classes A, B and C dated
                July 1, 1999.#

99.(e).3        Distribution Plans between the Registrant and John Hancock
                Funds for John Hancock Core Value Fund Classes A, B and C dated
                July 1, 1999.#

99.(f)          Bonus or Profit Sharing Contracts.  Not Applicable.

99.(g)          Custodian Agreements.   Master Custodian Agreement between John
                Hancock Mutual Funds and Investors Bank and Trust Company. *

99.(g).1        Master Custodian Agreement between John Hancock Mutual
                Funds and State Street Bank and Trust Company.*

99.(g).2        Amendment to Master Custodian Agreement between
                Registrant on behalf of John Hancock Berkeley Global
                Bond Fund and John Hancock Berkeley Overseas Growth
                Fund and State Street Bank and Trust Company.*

99.(g).3        Amended and Restated Master Custodian Agreement between John
                Hancock Mutual Funds for John Hancock International Equity Fund
                and State Street Bank and Trust Company dated
                March 9, 1999.*******

99.(g).4        Amended and Restated Master Custodian Agreement between John
                Hancock Mutual Funds for John Hancock Multi-Sector Growth Fund,
                John Hancock Small Capitalization Value Fund, John Hancock
                Dividend Performers Fund, John Hancock Active Bond Fund, John
                Hancock Small Capitalization Growth Fund, John Hancock
                Independence Core Equity Fund II, John Hancock Independence
                Value Fund, John Hancock Independence Growth Fund, John Hancock
                Independence Medium Capitalization Fund and John Hancock
                Balanced Fund and Investors Bank and Trust Company dated
                March 9, 1999.*******

99.(h)          Other Material Contracts.   Transfer Agency  and Service
                Agreement between the Registrant and John Hancock Investor
                Services Corporation dated January 30, 1995.*

99.(h).1        Amendment to Transfer Agency and Service Agreement between the
                Registrant and John Hancock Investor Services Corporation dated
                December 11, 1995.***


                                      C-12
<PAGE>



99.(h).2        Accounting and Legal Services Agreement between John Hancock
                Advisers, Inc. and Registrant as of January 1, 1996.****

99.(i)          Legal Opinion.  Legal Opinion with respect to the
                Registrant.+

99.(j)          Other Opinions. Auditors consent+

99.(k)          Omitted Financial Statements.  Not Applicable.

99.(l)          Initial Capital Agreement Subscription agreement between
                Registrant and John Hancock Advisers, Inc. dated
                January 12, 1995.*

99.(m)          Rule 12b-1 Plans.  None

99.(n)          Rule 18f-3 Plan.  John Hancock Funds Class A, Class B, Class C
                and Class I Multiple Class Plan Pursuant to Rule 18f-3 for John
                Hancock Core Growth Fund and John Hancock Core Value Fund.#


*        Previously filed electronically with post-effective  amendment number 1
         (file nos.  811-8852 and  33-86102)  on  September  8, 1995,  accession
         number 0000950135-95-001879.

**       Previously filed electronically with post-effective  amendment number 2
         (file nos.  811-8852 and  33-86102) on  September  25, 1995,  accession
         number 0000950135-95-001978.

***      Previously filed electronically with post-effective  amendment number 4
         (file nos. 811-8852 and 33-86102) on January 5, 1996,  accession number
         0000950135-96-000075.

****     Previously filed electronically with post-effective  amendment number 5
         (file nos.  811-8852 and 33-86102) on June 24, 1996,  accession  number
         0001010521-96-000102.

*****    Previously Filed electronically with post-effective  amendment number 7
         file nos.  811-8852 and 33-86102) on April 30, 1997,  accession  number
         0001010521-97-000281.

******   Previously filed electronically with post-effective amendment number
         8 file nos. 811-8852 and 33-86102 on April 29, 1998, accession number
         0001010521-98-000241.

*******  Previously filed electronically with post-effective amendment number
         9 (file nos. 811-8852 and 33-86102) on April 27, 1999, accession number
         0001010521-99-000192.

#        Previously filed electronically with post-effective amendment number
         10 (file number 811-8852 and 33-86102) on July 28, 1999, accession
         number 0001010521-99-000251.

+        Filed herewith.


                                      C-13





                     JOHN HANCOCK INSTITUTIONAL SERIES TRUST

                      John Hancock Independence Growth Fund
                      John Hancock Independence Value Fund

                     Designation of Existing Class of Shares

                      John Hancock Independence Growth Fund
    Establishment and Designation of New Class A, Class B and Class C Shares

                      John Hancock Independence Value Fund
    Establishment and Designation of New Class B, Class C and Class I Shares

                     Change of Names of Two Series of Shares
                            of Beneficial Interest of
                      John Hancock Independence Growth Fund
                      John Hancock Independence Value Fund
            Each a Series of John Hancock Institutional Series Trust


            Designation of Existing Class of Shares as Class I Shares
    Establishment and Designation of New Class A, Class B and Class C Shares

         The  undersigned,  being a majority  of the  Trustees  of John  Hancock
Institutional Series Trust, a Massachusetts business trust (the "Trust"), acting
pursuant to Sections 5.1 and 5.11 of the  Declaration of Trust dated October 31,
1994,  as amended  from time to time (the  "Declaration  of  Trust"),  do hereby
designate the existing  class of shares and  establish and designate  additional
classes  of shares of John  Hancock  Independence  Growth  Fund (the  "Fund") as
follows:

      1. The existing class of shares is hereby designated as Class I Shares.

      2. The additional classes of Shares of the Fund established and designated
         hereby are "Class A Shares", "Class B Shares" and "Class C Shares".

      3. Class A Shares,  Class B Shares and Class C Shares shall be entitled to
         all  of the  rights  and  preferences  accorded  to  Shares  under  the
         Declaration of Trust.

      4. The  purchase  price of Class A  Shares,  Class B  Shares  and  Class C
         Shares,  the  method  of  determining  the net  asset  value of Class A
         Shares,  Class B Shares and Class C Shares,  and the relative  dividend
         rights of holders of Class A Shares,  Class B Shares and Class C Shares
         shall be  established  by the Trustees of the Trust in accordance  with
         the provisions of the Declaration of Trust and shall be as set forth in
         the  Prospectus  and  Statement of Additional  Information  of the Fund
         included in the Trust's Registration Statement, as amended from time to
         time,  under  the  Securities  Act  of  1933,  as  amended  and/or  the
         Investment Company Act of 1940, as amended.


<PAGE>



            Designation of Existing Class of Shares as Class A Shares
    Establishment and Designation of New Class B, Class C and Class I Shares

         The  undersigned,  being a majority  of the  Trustees  of John  Hancock
Institutional Series Trust, a Massachusetts business trust (the "Trust"), acting
pursuant to Sections 5.1 and 5.11 of the  Declaration of Trust dated October 31,
1994,  as amended  from time to time (the  "Declaration  of  Trust"),  do hereby
designate the existing  class of shares and  establish and designate  additional
classes  of shares of John  Hancock  Independence  Value  Fund (the  "Fund")  as
follows:

      1. The existing class of shares is hereby designated as Class A Shares.

      2. The additional classes of Shares of the Fund established and designated
         hereby are "Class B Shares", "Class C Shares" and "Class I Shares".

      3. Class B Shares,  Class C Shares and Class I Shares shall be entitled to
         all  of the  rights  and  preferences  accorded  to  Shares  under  the
         Declaration of Trust.

      4. The  purchase  price of Class B  Shares,  Class C  Shares  and  Class I
         Shares,  the  method  of  determining  the net  asset  value of Class B
         Shares,  Class C Shares and Class I Shares,  and the relative  dividend
         rights of holders of Class B Shares,  Class C Shares and Class I Shares
         shall be  established  by the Trustees of the Trust in accordance  with
         the provisions of the Declaration of Trust and shall be as set forth in
         the  Prospectus  and  Statement of Additional  Information  of the Fund
         included in the Trust's Registration Statement, as amended from time to
         time,  under  the  Securities  Act  of  1933,  as  amended  and/or  the
         Investment Company Act of 1940, as amended.


                     Change of Names of Two Series of Shares

         The  undersigned,  being a majority  of the  Trustees  of John  Hancock
Institutional Series Trust, a Massachusetts business trust (the "Trust"), hereby
amend the Trust's  Declaration  of Trust dated October 31, 1994, as amended from
time to time, to the extent necessary to reflect the change of the names of John
Hancock  Independence  Growth  Fund to John  Hancock  Core  Growth Fund and John
Hancock Independence Value Fund to John Hancock Core Value Fund.

         The  Declaration of Trust is hereby amended to the extent  necessary to
reflect  the  following:  1) for John  Hancock  Independence  Growth  Fund,  the
designation of the existing class of shares as Class I Shares, the establishment
and designation of new Class A, Class B, and Class C Shares; 2) for John Hancock
Independence  Value Fund,  the  designation  of the existing  class of shares as
Class A Shares and the  establishment  and  designation of new Class I, Class B,
and Class C Shares;  and 3) the  change of names of two  series of  shares,  all
effective July 1, 1999.

         Capitalized  terms not otherwise defined herein shall have the meanings
set forth in the Declaration of Trust.


<PAGE>



         IN WITNESS  WHEREOF,  the undersigned  have executed this instrument on
the 8th day of June 1999.


/s/Edward J. Boudreau, Jr.                              /s/Charles L. Ladner
- --------------------------                              --------------------
Edward J. Boudreau, Jr.                                 Charles L. Ladner

/s/Stephen L. Brown
- -------------------                                     -------------------
Stephen L. Brown                                        Leo E. Linbeck, Jr.

/s/James F. Carlin                                      /s/Steven R. Pruchansky
- ------------------                                      -----------------------
James F. Carlin                                         Steven R. Pruchansky

/s/William H. Cunningham                                /s/Richard S. Scipione
- ------------------------                                ----------------------
William H. Cunningham                                   Richard S. Scipione

/s/Ronald R. Dion                                       /s/Norman H. Smith
- -----------------                                       ------------------
Ronald R. Dion                                          Norman H. Smith

/s/ Harold R. Hiser, Jr                                 /s/John P. Toolan
- -----------------------                                 -----------------
Harold R. Hiser, Jr.                                    John P. Toolan

/s/Anne C. Hodsdon
- ------------------
Anne C. Hodsdon




<PAGE>


         The Declaration of Trust, a copy of which, together with all amendments
thereto,  is on file in the office of the Secretary of State of The Commonwealth
of Massachusetts,  provides that no Trustee,  officer,  employee or agent of the
Trust  or  any  Series  thereof  shall  be  subject  to any  personal  liability
whatsoever  to any  Person,  other  than to the  Trust or its  shareholders,  in
connection  with Trust  Property  or the  affairs  of the Trust,  save only that
arising  from bad faith,  willful  misfeasance,  gross  negligence  or  reckless
disregard of his/her  duties with  respect to such Person;  and all such Persons
shall look solely to the Trust Property, or to the Trust Property of one or more
specific  Series of the  Trust if the  claim  arises  from the  conduct  of such
Trustee,  officer,  employee  or agent  with  respect to only such  Series,  for
satisfaction  of claims of any nature arising in connection  with the affairs of
the Trust.


COMMONWEALTH OF MASSACHUSETTS )
                              )ss
COUNTY OF SUFFOLK             )

         Then personally appeared the above-named Edward J. Boudreau, Jr.,
Stephen L. Brown, James F. Carlin, William H. Cunningham, Ronald R. Dion, Harold
R. Hiser, Jr., Anne C. Hodsdon, Charles L. Ladner, Steven R. Pruchansky, Richard
S. Scipione, Norman H. Smith and John P. Toolan, who acknowledged the foregoing
instrument to be his or her free act and deed, before me, this 8th day of June,
1999.

                                                /s/ Anne Marie White
                                                --------------------
                                                Notary Public

                                                My Commission Expires:10/20/00




July 27, 1999

John Hancock Institutional Series Trust
101 Huntington Avenue
Boston, MA 02199

RE:      John Hancock Institutional Series Trust
         John Hancock Active Bond Fund
         John Hancock Dividend Performers Fund
         John Hancock Independence Balanced Fund
         John Hancock Independence Diversified Core Equity Fund II
         John Hancock Independence Growth Fund
         John Hancock Independence Medium Capitalization Fund
         John Hancock Independence Value Fund
         John Hancock International Equity Fund
         John Hancock Multi-Sector Growth Fund
         John Hancock Small Capitalization Growth Fund
         John Hancock Small Capitalization Value Fund
         File Nos. 33-86102; 811-8852 (0000932683)

Ladies and Gentlemen:

In  connection  with the  filing of  Post-Effective  Amendment  No. 11 under the
Securities  Act of 1933,  as  amended,  Amendment  No. 12 under  the  Investment
Company Act of 1940, as amended,  John Hancock  Institutional  Series Trust (the
"Trust") it is the opinion of the undersigned that such shares when sold will be
legally issued, fully paid and nonassessable.

In connection with this opinion it should be noted that the Fund is an entity of
the type generally known as a "Massachusetts business trust." The Trust has been
duly  organized and is validly  existing under the laws of the  Commonwealth  of
Massachusetts. Under Massachusetts law, shareholders of a Massachusetts business
trust may be held personally  liable for the obligations of the Trust.  However,
the Trust's Declaration of Trust disclaims shareholder liability for obligations
of  the  Trust  and   indemnifies   the   shareholders  of  a  Fund,  with  this
indemnification to be paid solely out of the assets of that Fund. Therefore, the
shareholder's risk is limited to circumstances in which the assets of a Fund are
insufficient to meet the obligations asserted against that Fund's assets.


Sincerely,

/s/ Theresa Apruzzese
- ---------------------
Theresa Apruzzese
Assistant Secretary
Member of Massachusetts Bar



                          INDEPENDENT AUDITORS' CONSENT


We consent to the incorporation by reference into the Prospectus and Statement
of Additional Information in this Post-Effective Amendment No. 11 to the
Registration Statement (1933 Act File No. 33-86102) of John Hancock
Institutional Series Trust of our report dated April 2, 1999 on the financial
statements and financial highlights included in the Annual Report to
Shareholders of John Hancock Independence Growth & Income Fund (formerly John
Hancock Independence Diversified Core Equity Fund II),

We further consent to the references to our firm under the heading "Independent
Auditors" in the Statement of Additional Information.




/s/Deloitte & Touche LLP
- ------------------------
Deloitte & Touche LLP


Boston, Massachusetts
July 28, 1999




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