INDEPENDENT AUDITORS' CONSENT
We consent to the incorporation by reference in this Post-Effective Amendment
No. 13 to the Registration Statement of the John Hancock Institutional Series
Trust (1933 Act File No. 33-86102) on behalf of the John Hancock Active Bond
Fund, John Hancock Dividend Performers Fund, John Hancock Medium Capitalization
Growth Fund, John Hancock Small Capitalization Value Fund, John Hancock Small
Capitalization Growth Fund, John Hancock International Equity Fund, John Hancock
Independence Diversified Core Equity Fund II, John Hancock Independence Medium
Capitalization Fund, John Hancock Independence Balanced Fund, John Hancock Core
Value Fund, and John Hancock Core Growth Fund of our reports dated March 31,
2000, included in the Annual Report to Shareholders for the year ended February
29, 2000, in the Statements of Additional Information which are part of such
registration statement.
We also consent to the reference to our firm under the heading "Financial
Highlights" in the Prospectuses and under the caption "Independent Auditors" in
the Statements of Additional Information.
/s/ Deloitte & Touche LLP
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Deloitte & Touche LLP
Boston, Massachusetts
June 27, 2000
