<PAGE> 1
Filed Pursuant to Rule 424(b)(3)
File Number 333-72225
PROSPECTUS SUPPLEMENT NO. 1
(To Prospectus Dated February 26, 1999)
AVIGEN, INC.
1,725,708 SHARES
COMMON STOCK
Stated in the Prospectus, dated Feburary 26, 1999, with respect to the
offer and sale of 1,725,708 shares of common stock of Avigen, Inc., under the
caption "Selling Stockholders," is that Paluel Marmont Banque is selling 131,868
shares of Avigen's common stock. Paluel Marmont Banque, however, was the record
holder acting as nominee for Tocqueville Finance S.A., the actual selling
stockholder of these shares. As a result of the above, the disclosure regarding
beneficial ownership of these shares in the table of selling stockholders under
the caption "Selling Stockholders" in the Prospectus is amended as below. All
other aspects of this table, including with respect to the other selling
stockholders listed in the table, remain the same.
SHARES BENEFICIALLY OWNED PRIOR TO OFFERING
<TABLE>
<CAPTION>
SHARES BEING
SELLING STOCKHOLDER NUMBER PERCENT OFFERED
<S> <C> <C> <C>
Tocqueville Finance S.A. (1) 131,868 1.29% 131,868
</TABLE>
THE DATE OF THIS PROSPECTUS SUPPLEMENT IS JANUARY 31, 2000.
