MERRILL LYNCH GLOBAL INSTITUTIONAL SERIES INC
RW, 1995-05-26
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               MERRILL LYNCH GLOBAL INSTITUTIONAL SERIES, INC.



                                        May 26, 1995



U.S. Securities and Exchange Commission
450 Fifth Street, N. W.
Washington, D.C.  20549

          Re:  Merrill Lynch Global Institutional Series, Inc. -
               CIK No. 0000932976
               Request for Withdrawal of Registration Statement
               on Form N-1A; File No. 33-57815                  
               ------------------------------------------------


Ladies and Gentlemen:

     On behalf of Merrill Lynch Global Institutional Series, Inc. (the
"Fund") and pursuant to Rule 477(a) under the Securities Act of 1933, as
amended (the "Securities Act"), I respectfully request the Securities and
Exchange Commission (the "Commission") to consent to the withdrawal of the
Fund's registration statement on Form N-1A, filed and accepted by the
Commission on February 23, 1995 (Accession No. 0000905148-95-000041).  The
Fund had filed an initial registration statement on Form N-1A on November
23, 1994.  On February 23, 1995, the Fund attempted to file Pre-Effective
Amendment No. 1 to its registration statement on Form N-1A.  This filing
was accepted by the Commission, but due to a technical error the EDGAR
submission form type mistakenly described the filing as "N-1A EL" rather
than "N-1A/A", the proper form type for pre-effective amendment filings. 
Once this error was brought to our attention, the Fund corrected the form
type of its February 23, 1995 filing by filing on April 13, 1995 the exact
same pre-effective amendment under EDGAR form type "N-1A/A".  This second
filing of Pre-Effective Amendment No. 1 was accepted by the Commission,
and the date of this second filing was readjusted to February 23, 1995.

     Pursuant to Rule 477(a) under the Securities Act, the Fund now
requests the Commission to consent to the withdrawal of the Fund's first
filing on February 23, 1995 of the Fund's Pre-Effective Amendment No. 1 to
its registration statement on Form N-1A (File No. 33-57815; Accession No.
0000905148-95-000041).  Such withdrawal would be consistent with the
public interest and the protection of investors, as the sole reason for
the Fund's request for withdrawal of this registration statement is the
incorrect EDGAR form type used in such submission.


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     Please direct any questions or comments with respect to this request
to Robert C. Torch of Brown & Wood a (212) 839-8561.


                                        Sincerely,

                                         /s/ Gerald M. Richard                 
                                        ------------------------
                                        Gerald M. Richard
					Treasurer (Principal
					Financial and Accounting
					Officer)
                                        
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