SHAW D E INVESTMENTS LP
SC 13G/A, 1999-02-09
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                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                              ------------------

                                 SCHEDULE 13G

                              ------------------

           INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2
                  UNDER THE SECURITIES EXCHANGE ACT OF 1934

                              (AMENDMENT NO.) 1


                              Pharmacopeia, Inc.
                               (NAME OF ISSUER)

                                 Common Stock
                        (TITLE OF CLASS OF SECURITIES)

                                  71713B104
                                (CUSIP NUMBER)

                              December 31, 1998
           (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which the Schedule
is filed.

[ ] Rule 13d-1(b)

[X]  Rule 13d-1(c)

[ ]  Rule  13d-1(d)

*    The remainder of this cover page shall be filled out for a reporting
     person's initial filing on this form with respect to the subject
     class of securities, and for any subsequent amendment containing
     information which would alter the disclosures provided in a prior
     cover page.

     The information required in the remainder of this cover page shall
     not be deemed to be "filed" for the purpose of Section 18 of the
     Securities Exchange Act of 1934 ("Act") or otherwise subject to the
     liabilities of that section of the Act but shall be subject to all
     other provisions of the Act (however, see the Notes).

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CUSIP No.  71713B104             SCHEDULE 13G

1.   Name of Reporting Person
     I.R.S. Identification No. of Above Person (entities only)

     D.E. Shaw Investment Group, L.P.
     13-3544420

2.   Check the Appropriate Box if a Member of a Group    (a) [ ]    (b) [X]


3.   SEC Use Only


4.   Citizenship or Place of Organization

     Delaware

Number of Shares         5.   Sole Voting Power

 Beneficially                 0

 Owned by Each           6.   Shared Voting Power

Reporting Person              1,274,579

     With                7.   Sole Dispositive Power

                              0

                         8.   Shared Dispositive Power

                              1,274,579

9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     1,274,579

10.  Check if the Aggregate Amount in Row 9 Excludes Certain Shares  [ ]

11.  Percent of Class Represented by Amount in Row 9

     6.67%

12.  Type of Reporting Person

     PN

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CUSIP No.                        SCHEDULE 13G

1.   Name of Reporting Person
     I.R.S. Identification No. of Above Person (entities only)

     David E. Shaw

2.   Check the Appropriate Box if a Member of a Group    (a) [ ]    (b) [X]


3.   SEC Use Only


4.   Citizenship or Place of Organization

     United States

Number of Shares         5.   Sole Voting Power

 Beneficially                 0

 Owned by Each           6.   Shared Voting Power

Reporting Person              1,274,579

     With                7.   Sole Dispositive Power

                              0

                         8.   Shared Dispositive Power

                              1,274,579

9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     1,274,579

10.  Check if the Aggregate Amount in Row 9 Excludes Certain Shares  [ ]

11.  Percent of Class Represented by Amount in Row 9

     6.67%

12.  Type of Reporting Person

     IN

<PAGE>


ITEM 1(a).        NAME OF ISSUER:

                  Pharmacopeia, Inc. (the "Company")

ITEM 1(b).        ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

                  Princeton Forrestal Center, 101 College Road East, 
                  Princeton, NJ 08540

ITEM 2(a).        NAME OF PERSON FILING:

                  D. E. Shaw Investment Group, L.P. ("Inv Group LP")
                  David E. Shaw ("David Shaw")

ITEM 2(b).        ADDRESS OF PRINCIPAL OFFICE OR, IF NONE, RESIDENCE:

                  120 West 45th Street, 39th Floor, Tower 45, New York, 
                  NY 10036

ITEM 2(c).        CITIZENSHIP:

                  Inv Group LP is a limited partnership organized under the
                  laws of the State of Delaware.

                  David Shaw is a citizen of the United States.

ITEM 2(d).        TITLE OF CLASS OF SECURITIES:

                  Common Stock

ITEM 2(e).        CUSIP NUMBER:
                  71713B104

ITEM 3.           IF THIS STATEMENT IS FILED PURSUANT TO RULES 13d-1(b),
                  OR 13d-2(b), CHECK WHETHER PERSON FILING IS A:

                  (a) [ ] Broker or dealer registered under Section 15 of the 
                          Act;

                  (b) [ ] Bank as defined in Section 3(a)(6) of the Act;

                  (c) [ ] Insurance Company as defined in Section 3(a)(19) of
                          the Act;

                  (d) [ ] Investment Company registered under Section 8 of the
                          Investment Company Act;

                  (e) [ ] Investment Adviser registered under Section 203 of
                          the Investment Advisers Act of 1940;

                  (f) [ ] Employee Benefit Plan, Pension Fund which is subject
                          to the provisions of the Employee Retirement Income 
                          Security Act of 1974 or Endowment Fund; see Rule 
                          13d-1(b)(1)(ii)(F);

                  (g) [ ] Parent Holding Company, in accordance with Rule
                          13d-1(b)(ii)(G); see item 7;

                  (h) [ ] A Savings Association as defined in Section 3(b) of 
                          the Federal Deposit Insurance Act (12 U.S.C. 1813);

                  (i) [ ] A Church Plan that is excluded from the definition 
                          of an investment company under Section 3(c)(14) of 
                          the Investment Company Act of 1940 (15 U.S.C. 80a-3); 
                          and

                  (j) [ ] A Group, provided that all the members are persons 
                          specified in accordance with Section 
                          240.13d-1(b)(1)(ii)(A) through (I).

                  If this statement is filed pursuant to Rule 13d-1(c), check 
                  this box.   [X]
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ITEM 4.           OWNERSHIP.

                  (a)      Amount beneficially owned:

                           Inv Group LP:     1,274,579
                           David Shaw:       1,274,579

                  (b)      Percent of class:

                           Inv Group LP:    6.67%
                           David Shaw:      6.67%    (based on 19,120,604 
                                                     shares outstanding)

                  (c)      Number of shares as to which such person has:

                           (i)      Sole power to vote or direct the vote

                           Inv Group LP:    -0-
                           David Shaw:      -0-

                           (ii)     Shared power to vote or direct the vote

                           Inv Group LP:    1,274,579
                           David Shaw:      1,274,579

                  David Shaw owns directly no shares. By reason of Rule 13d-3
                  under the Securities Exchange Act of 1934 and by virtue of
                  David Shaw's position as President and sole shareholder of
                  D. E. Shaw & Co., Inc., the general partner of D. E. Shaw &
                  Co., L.P., itself the general partner of Inv Group LP, David
                  Shaw may be deemed to own beneficially 1,274,579 shares,
                  comprising the 1,274,579 owned directly by Inv Group LP.
                  Therefore, David Shaw may be deemed to beneficially own
                  approximately 6.67% of the outstanding shares. David Shaw
                  disclaims beneficial ownership of such 1,274,579 shares.

ITEM 5.           OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

                  Not applicable

ITEM 6.           OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER 
                  PERSON.

                  No person other than each respective owner and general
                  partner referred to herein is known to have the right to
                  receive or the power to direct the receipt of dividends
                  from, or the proceeds of the sale of, the shares.

ITEM 7.           IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
                  ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT 
                  HOLDING COMPANY

                  Not applicable.

ITEM 8.           IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

                  Not applicable.

ITEM 9.           NOTICE OF DISSOLUTION OF GROUP.

                  Not applicable.
<PAGE>


ITEM 10.          CERTIFICATION. (if filing pursuant to Rule 13d-1(b))

                  By signing below D. E. Shaw Investment Group, L.P. and David
                  E. Shaw certify that, to the best of their knowledge and
                  belief, the securities referred to above were acquired in the
                  ordinary course of business, were not acquired for the purpose
                  of and do not have the effect of changing or influencing the
                  control of the issuer of such securities and were not acquired
                  in connection with or as a participant in any transaction
                  having such purposes or effect.


         SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and
correct.

         February 9, 1999

         D. E. SHAW INVESTMENT GROUP, L.P.

         By:   D. E. SHAW & CO., L.P.
               General Partner

         By:   /s/ Daniel Fishbane
               (Signature)

         Daniel Fishbane/
         Managing Director
               (Name/Title)


         DAVID E. SHAW

         By: /s/ Daniel Fishbane
                 Attorney-in-Fact


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After reasonable inquiry and to the best of their knowledge and belief, the
undersigned certify that the information set forth in this statement is true,
complete and correct. A power of attorney, dated January 14, 1997, granted by
David Shaw in favor of Daniel Fishbane, is attached hereto.

                                    February 9, 1999

                                    D. E. Shaw Investment Group, L.P.
                                    By: D. E. Shaw & Co., L.P. as
                                    General Partner

                                    By:      
                                          ----------------------
                                          Daniel Fishbane
                                          Managing Director

    
                                    David E. Shaw
                                    By:     
                                          ----------------------
                                          Daniel Fishbane
                                          Attorney-in-Fact for David E. Shaw

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                              POWER OF ATTORNEY
                             FOR CERTAIN FILINGS
                     UNDER THE SECURITIES EXCHANGE ACT OF
                                     1934

I, David E. Shaw, hereby make, constitute and appoint each of:

         Lou Salkind

         Stu Steckler

         Anne Dinning and

         Danny Fishbane

Acting individually, as my agent and attorney-in-fact, with full power or
substitution, for the purpose of, from time to time, executing in my name, my
individual capacity and/or my capacity as President of D. E. Shaw & Co., Inc.
(acting for itself or as the general partner of D. E. Shaw & Co., L.P.) all
documents, certificates, instruments, statements, other filings and amendments
to the foregoing (collectively, "documents") determined by such person to be
necessary or appropriate to comply with ownership or control-person reporting
requirements imposed by any United States or non-United States governmental or
regulatory authority, including without limitation Forms 3, 4, 5, 13D, 13F and
13G required to be filed with the Securities and Exchange Commission; and
delivering, furnishing or filing any such documents with the appropriate
governmental or regulatory authority. Any such determination shall be
conclusively evidenced by such person's execution and delivery, furnishing or
filing of the applicable document.

This power of attorney shall be valid from the date hereof.

IN WITNESS WHEREOF, I have executed this instrument as of the date set forth
below.

Date:    January 14, 1997

/s/ David E. Shaw
- -----------------
David E. Shaw
New York, New York



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