MIRAVANT MEDICAL TECHNOLOGIES
SC 13D/A, 1998-12-02
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*

                       Miravant Medical Technologies, Inc.
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                     Common Stock, Par Value $0.01 Per Share
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    69329P103
             -------------------------------------------------------
                                 (CUSIP Number)

                               Richard T. Collier
                                 General Counsel
                            Pharmacia & Upjohn, Inc.
                               95 Corporate Drive
                            Bridgewater, NJ 08807 USA
- --------------------------------------------------------------------------------
            (Name, Address and Telephone Number of Person Authorized
                     to Receive Notices and Communications)

                                December 1, 1998
             -------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  that is the subject of this  Schedule  13D, and is filing this
schedule because of ss.ss. 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box |_|.

NOTE:  Schedules  filed in paper format shall include a signed original and five
copies of the  schedule,  including all  exhibits.  See ss.  240.13d-7 for other
parties to whom copies are to be sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


                                                                 SEC 1746(12-91)




<PAGE>



                                  SCHEDULE 13D

- --------------------------------                --------------------------------
CUSIP No.      69329P103                           Page   2   of   20   Pages
          ----------------------                       ------    ------ 
- --------------------------------                --------------------------------


- --------------------------------------------------------------------------------
 1   NAME OF REPORTING PERSONS.
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

                         The Pharmacia & Upjohn Company
- --------------------------------------------------------------------------------
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

                                                                   (a) |_|
                                                                   (b) |_|
- --------------------------------------------------------------------------------
 3   SEC USE ONLY


- --------------------------------------------------------------------------------
 4   SOURCE OF FUNDS (SEE INSTRUCTIONS)

                                       WC
- --------------------------------------------------------------------------------
 5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
     ITEMS 2(d) OR 2(e)                                              |_|

- --------------------------------------------------------------------------------
 6   CITIZENSHIP OR PLACE OF ORGANIZATION

                                    Delaware
- --------------------------------------------------------------------------------
NUMBER OF           7    SOLE VOTING POWER
SHARES                             125,001
BENEFICIALLY       -------------------------------------------------------------
OWNED BY            8    SHARED VOTING POWER
EACH                                 -0-
REPORTING          -------------------------------------------------------------
PERSON              9    SOLE DISPOSITIVE POWER
WITH                               125,001
                   -------------------------------------------------------------
                    10   SHARED DISPOSITIVE POWER
                                     -0-
- --------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                                   125,001
- --------------------------------------------------------------------------------
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS)                                                   |_|

- --------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                                  0.8%
- --------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

                                  CO
- --------------------------------------------------------------------------------





<PAGE>



                                  SCHEDULE 13D

- --------------------------------                --------------------------------
CUSIP No.      69329P103                           Page   3   of   20   Pages
          ----------------------                       ------    ------ 
- --------------------------------                --------------------------------


- --------------------------------------------------------------------------------
 1   NAME OF REPORTING PERSONS.
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

                         Pharmacia & Upjohn S.p.A.
- --------------------------------------------------------------------------------
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

                                                                   (a) |_|
                                                                   (b) |_|
- --------------------------------------------------------------------------------
 3   SEC USE ONLY


- --------------------------------------------------------------------------------
 4   SOURCE OF FUNDS (SEE INSTRUCTIONS)

                                       WC
- --------------------------------------------------------------------------------
 5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
     ITEMS 2(d) OR 2(e)                                              |_|

- --------------------------------------------------------------------------------
 6   CITIZENSHIP OR PLACE OF ORGANIZATION

                                    Italy
- --------------------------------------------------------------------------------
NUMBER OF           7    SOLE VOTING POWER
SHARES                             600,000
BENEFICIALLY       -------------------------------------------------------------
OWNED BY            8    SHARED VOTING POWER
EACH                                 -0-
REPORTING          -------------------------------------------------------------
PERSON              9    SOLE DISPOSITIVE POWER
WITH                               600,000
                   -------------------------------------------------------------
                    10   SHARED DISPOSITIVE POWER
                                     -0-
- --------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                                   600,000
- --------------------------------------------------------------------------------
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS)                                                   |_|

- --------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                                  3.7%
- --------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

                                  CO
- --------------------------------------------------------------------------------






<PAGE>



                                  SCHEDULE 13D

- --------------------------------                --------------------------------
CUSIP No.      69329P103                           Page   4   of   20   Pages
          ----------------------                       ------    ------ 
- --------------------------------                --------------------------------


- --------------------------------------------------------------------------------
 1   NAME OF REPORTING PERSONS.
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

                         Pharmacia & Upjohn AB
- --------------------------------------------------------------------------------
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

                                                                   (a) |_|
                                                                   (b) |_|
- --------------------------------------------------------------------------------
 3   SEC USE ONLY


- --------------------------------------------------------------------------------
 4   SOURCE OF FUNDS (SEE INSTRUCTIONS)

                                       AF
- --------------------------------------------------------------------------------
 5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
     ITEMS 2(d) OR 2(e)                                              |_|

- --------------------------------------------------------------------------------
 6   CITIZENSHIP OR PLACE OF ORGANIZATION

                                    Sweden
- --------------------------------------------------------------------------------
NUMBER OF           7    SOLE VOTING POWER
SHARES                             600,000
BENEFICIALLY       -------------------------------------------------------------
OWNED BY            8    SHARED VOTING POWER
EACH                                 -0-
REPORTING          -------------------------------------------------------------
PERSON              9    SOLE DISPOSITIVE POWER
WITH                               600,000
                   -------------------------------------------------------------
                    10   SHARED DISPOSITIVE POWER
                                     -0-
- --------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                                   600,000
- --------------------------------------------------------------------------------
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS)                                                   |_|

- --------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                                  3.7%
- --------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

                                  CO
- --------------------------------------------------------------------------------






<PAGE>



                                  SCHEDULE 13D

- --------------------------------                --------------------------------
CUSIP No.      69329P103                           Page   5   of   20   Pages
          ----------------------                       ------    ------ 
- --------------------------------                --------------------------------


- --------------------------------------------------------------------------------
 1   NAME OF REPORTING PERSONS.
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

                         Pharmacia & Upjohn International N.V.
- --------------------------------------------------------------------------------
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

                                                                   (a) |_|
                                                                   (b) |_|
- --------------------------------------------------------------------------------
 3   SEC USE ONLY


- --------------------------------------------------------------------------------
 4   SOURCE OF FUNDS (SEE INSTRUCTIONS)

                                       AF
- --------------------------------------------------------------------------------
 5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
     ITEMS 2(d) OR 2(e)                                              |_|

- --------------------------------------------------------------------------------
 6   CITIZENSHIP OR PLACE OF ORGANIZATION

                                    Netherlands
- --------------------------------------------------------------------------------
NUMBER OF           7    SOLE VOTING POWER
SHARES                             600,000
BENEFICIALLY       -------------------------------------------------------------
OWNED BY            8    SHARED VOTING POWER
EACH                                 -0-
REPORTING          -------------------------------------------------------------
PERSON              9    SOLE DISPOSITIVE POWER
WITH                               600,000
                   -------------------------------------------------------------
                    10   SHARED DISPOSITIVE POWER
                                     -0-
- --------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                                   600,000
- --------------------------------------------------------------------------------
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS)                                                   |_|

- --------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                                  3.7%
- --------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

                                  OO
- --------------------------------------------------------------------------------






<PAGE>



                                  SCHEDULE 13D

- --------------------------------                --------------------------------
CUSIP No.      69329P103                           Page   6   of   20   Pages
          ----------------------                       ------    ------ 
- --------------------------------                --------------------------------


- --------------------------------------------------------------------------------
 1   NAME OF REPORTING PERSONS.
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

                         Pharmacia & Upjohn, Inc.
- --------------------------------------------------------------------------------
 2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

                                                                   (a) |_|
                                                                   (b) |_|
- --------------------------------------------------------------------------------
 3   SEC USE ONLY


- --------------------------------------------------------------------------------
 4   SOURCE OF FUNDS (SEE INSTRUCTIONS)

                                       AF
- --------------------------------------------------------------------------------
 5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
     ITEMS 2(d) OR 2(e)                                              |_|

- --------------------------------------------------------------------------------
 6   CITIZENSHIP OR PLACE OF ORGANIZATION

                                    Delaware
- --------------------------------------------------------------------------------
NUMBER OF           7    SOLE VOTING POWER
SHARES                             725,001
BENEFICIALLY       -------------------------------------------------------------
OWNED BY            8    SHARED VOTING POWER
EACH                                 -0-
REPORTING          -------------------------------------------------------------
PERSON              9    SOLE DISPOSITIVE POWER
WITH                               725,001
                   -------------------------------------------------------------
                    10   SHARED DISPOSITIVE POWER
                                     -0-
- --------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                                   725,001
- --------------------------------------------------------------------------------
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 
     (SEE INSTRUCTIONS)                                                   |_|

- --------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                                  4.5%
- --------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

                                  CO, HC
- --------------------------------------------------------------------------------






<PAGE>



CUSIP Number: 69329P103                                            Page 7 of 20



         Pharmacia & Upjohn AB (formerly Pharmacia AB), a Swedish corporation
("P&U AB"), Pharmacia & Upjohn S.p.A. (formerly Pharmacia S.p.A.), an Italian
corporation ("P&U S.p.A." and, together with P&U AB, the "Original Reporting
Persons") The Pharmacia & Upjohn Company, a Delaware corporation ("P&U Co."),
Pharmacia & Upjohn International N.V., a "check the box" entity incorporated
in the Netherlands ("P&U NV") and Pharmacia & Upjohn, Inc. ("P&U Inc.", and
together with P&U AB, P&U Co., P&U BV and P&U S.p.A., the "Reporting Persons")
hereby amend the reports on Schedule 13D for each of the Original Reporting
Persons, each dated July 7, 1995 (the "Original Schedule 13Ds"), filed by the
Original Reporting Persons with respect to shares of Common Stock, par value
$.01 per share (the "Shares"), of Miravant Medical Technologies, Inc. (formerly
PDT, Inc.), a Delaware corporation ("Miravant") beneficially owned by them. As
the Original Schedule 13Ds were originally filed in paper format, this amendment
restates and amends the entire text of the Original Schedule 13Ds pursuant to
Rule 13d-2(e) of the General Rules and Regulations under the Securities Exchange
Act of 1934.

ITEM 1.  SECURITY AND ISSUER

         The class of equity securities to which this Amendment to the Original
Schedule 13Ds relate is the Shares of Miravant. The principal executive office
of Miravant is located at 7408 Hollister Avenue, Santa Barbara, California
93117.

ITEM 2.  IDENTITY AND BACKGROUND

         The principal business address of P&U S.p.A. is Pharmacia & Upjohn
S.p.A., via Robert Koch 1.2, 75017 Milan, Italy. The principal business address
of P&U AB is Pharmacia & Upjohn AB, S-171 97 Stockholm, Sweden. The principal
business address of P&U NV is Pharmacia & Upjohn International N.V.,
Houttuinlaan 4, NL - 3447 GM Woerden, The Netherlands. The principal business
address of both P&U Inc. and P&U Co. is Pharmacia & Upjohn, Inc., 95 Corporate
Drive, Bridgewater, New Jersey 08807.

         P&U S.p.A. is an Italian corporation and a subsidiary of P&U AB, a
Swedish corporation, which, in turn, is a wholly owned subsidiary of P&U NV, a
"check the box" entity incorporated in The Netherlands. P&U NV and P&U Co. are
wholly owned subsidiaries of P&U Inc., a Delaware corporation. P&U Co. is the
successor to Pharmacia, Inc., a Minnesota corporation and a former wholly owned
subsidiary of P&U AB. The principal business




<PAGE>


CUSIP Number: 69329P103                                            Page 8 of 20



of each of the Reporting Persons is the development, production, marketing and
sale of pharmaceutical products.

         The name, residence or business address, present principal occupation
or employment, and the citizenship of each of each director and executive
officer of (i) P&U S.p.A. is set forth in Schedule I hereto and incorporated
herein by reference, (ii) P&U Co. is set forth in Schedule II hereto and
incorporated herein by reference, (iii) P&U Inc. is set forth in Schedule III
hereto and incorporated herein by reference.

         None of the Reporting Persons, or to the best knowledge and belief of
the Reporting Persons, any of the individuals listed in Schedule I, II or III
has, during the past five years, been convicted in any criminal proceeding
(excluding traffic violations or similar misdemeanors) or has been a party to a
civil proceeding of a judicial or administrative body of competent jurisdiction
and as a result of such proceeding was or is subject to a judgment, decree or
final order enjoining future violations of, or prohibiting or mandating
activities subject to, federal or state securities laws or finding any violation
with respect to such laws.

         This Item 2 is qualified in its entirety by reference to Schedules I,
II and III which are incorporated herein by reference.

ITEM 3.  SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION

         In 1994, Pharmacia, Inc., a former wholly owned subsidiary of P&U AB as
to which P&U Co. is the successor by merger, purchased 83,334 Shares of Miravant
and was granted a warrant to purchase an additional 41,667 Shares (the
"Warrant") for $1,000,008, the source of which funds was working capital. The
Warrant issued to Pharmacia, Inc. was not exercised and has expired.

         In 1995, P&U S.p.A. purchased 400,000 Shares of Miravant for
$12,000,000, the source of which funds was working capital.

         In 1995, pursuant to a 3 for 2 stock split, the holdings of Pharmacia,
Inc. were adjusted to




<PAGE>


CUSIP Number: 69329P103                                            Page 9 of 20



125,001 Shares and the holdings of P&U S.p.A. were adjusted to 600,000 Shares.

         The Reporting Persons have not sold any Shares of Miravant.

         None of the persons listed on Schedule I, II or III hereto has
contributed any funds or other consideration towards the purchase of the Shares
of Miravant reported in this statement.

ITEM 4.  PURPOSE OF TRANSACTION

         The Shares of Miravant described by this Schedule 13D were acquired for
investment purposes. Other than as set forth herein, the Reporting Persons do
not have plans or proposals which relate to or would result in any of the events
described by Items 4(a) through 4(j) of Schedule 13D.

         Pursuant to the Stock Purchase Agreement set forth as Exhibit A to this
Schedule 13D, Pharmacia S.p.A. and its affiliates are prohibited through July 7,
2000 from directly or indirectly acquiring, or agreeing, offering, seeking or
proposing to acquire any securities issued by Miravant without the prior written
consent of Miravant, except that Pharmacia S.p.A. and its affiliates may
purchase securities of Miravant in ordinary brokerage or trading transactions by
a securities broker or dealer or purchases by an institutional investor solely
for investment purposes aggregating less than 5% of Miravant's outstanding
voting securities or less than 10% of any class of Miravant's outstanding
non-voting securities.

         Representatives of the Reporting Persons have indicated to Miravant
their willingness to consider recommending that the Reporting Persons enter into
a transaction having terms consistent with those set forth in the P&U Proposed
Term Sheet set forth as Exhibit D to this Schedule 13D, which is incorporated
herein by reference (the "P&U Proposed Term Sheet"). The P&U Proposed Term Sheet
contemplates, among other things, the acquisition by one or more of the
Reporting Persons of additional securities of Miravant. Miravant has supplied
representatives of the Reporting Persons with the Miravant Proposed Term Sheet
set forth as Exhibit E to this Schedule 13D, which is incorporated herein by
reference (the "Miravant Proposed Term Sheet"). Discussions concerning a
transaction of the type contemplated by the P&U Proposed Term Sheet and the
Miravant Proposed Term Sheet are at a highly preliminary stage. No assurances
can be given concerning whether any of the Reporting Persons or Miravant will
find such a transaction to be consistent with its respective objectives and the
Reporting Persons, on the one hand, and Miravant, on the other hand, have made
substantive modifications to the indications of interest represented by the P&U
Proposed Term Sheet and the Miravant Proposed Term Sheet, respectively.


<PAGE>


CUSIP Number: 69329P103                                           Page 10 of 20



Any of the Reporting Persons or Miravant may cease to consider such a
transaction at any time and for any or no reason, each in their sole discretion.
The P&U Proposed Term Sheet and the Miravant Proposed Term Sheet are not legally
binding agreements and they impose no obligation on any of the Reporting Persons
or Miravant to continue discussions. No assurances can be given concerning (i)
whether additional discussions between the Reporting Persons and Miravant will
occur, (ii) whether the Reporting Persons and Miravant will reach any agreement
providing for a transaction, (iii) whether and to what extent any such
transaction will relate to or result in any of the events described by Items
4(a) through 4(j) of Schedule 13D, or (iv) whether any such transaction will be
consummated.

         On or prior to October 31, 1998, the Reporting Persons ceased to be the
beneficial owners of more than five percent of the Shares because of the
issuance of additional Shares of Miravant by Miravant. Accordingly, the
statements contained in this Schedule 13D will not be amended or updated unless
and until such time as the Reporting Persons and their affiliates become the
beneficial owners of more than five percent of the Shares of Miravant. See 
Item 5.

ITEM 5.  INTEREST IN SECURITIES OF THE ISSUER

         (a) The percentage interest held by each Reporting Person presented
below is based on the number of Shares of Miravant reported to be outstanding as
of October 31, 1998 in Miravant's Quarterly Report on Form 10-Q for the quarter
ended September 30, 1998 (the "Outstanding Shares").

         P&U Co., as successor to Pharmacia, Inc., beneficially owns 125,001
shares, representing approximately 0.8% of the Outstanding Shares.

         P&U S.p.A. beneficially owns 600,000 Shares of Miravant, representing
approximately 3.7% of the Outstanding Shares.

         P&U AB may be deemed to beneficially own 600,000 Shares of Miravant,
representing approximately 3.7% of the Outstanding Shares.





<PAGE>


CUSIP Number: 69329P103                                           Page 11 of 20



         P&U NV may be deemed to beneficially own 600,000 Shares of Miravant,
representing approximately 3.7% of the Outstanding Shares.

         P&U Inc. may be deemed to beneficially own 725,001 Shares, representing
approximately 4.5% of the Outstanding Shares.

         None of the Reporting Persons, and to the knowledge of the Reporting
Persons, none of the persons listed in Schedules I, II and III hereto
beneficially owns any Shares of Miravant other than as set forth herein.

         (b) Each Reporting Person shares the power to vote or direct the vote
and dispose or direct the disposition of the Shares beneficially owned by such
Reporting Persons as indicated in pages 2 through 6 above.

         (c) None of the Reporting Persons and, to the knowledge of the
Reporting Persons, none of the persons listed on Schedule I, II or III hereto,
has been party to any transaction in Shares of Miravant during the past sixty
days.

         (d) No other person has the right to receive or the power to direct the
receipt of dividends from or proceeds from the sale of Shares of Miravant.

         (e) Based on the number of Shares reported outstanding in Miravant's
Quarterly Report on Form 10-Q for the quarter ended September 30, 1998, the
Reporting Persons ceased to be the beneficial owners of more than five percent
of the outstanding Shares of Miravant on or prior to October 31, 1998.
Accordingly, the statements contained in this Schedule 13D will not be amended
or updated unless and until such time as the Reporting Persons and their
affiliates become the beneficial owners of more than five percent of the Shares.

ITEM 6.  CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS
         WITH RESPECT TO SECURITIES OF THE ISSUER

         There are no contracts, arrangements, understandings or relationships
between the Reporting Persons (or their wholly owned subsidiaries) and other
persons with respect to the Shares of Miravant aside from the following:





<PAGE>


CUSIP Number: 69329P103                                           Page 12 of 20



     (a)  Stock Purchase Agreement, dated as of July 7, 1995, by and between
          PDT, Inc. and Pharmacia S.p.A. (the "Stock Purchase Agreement") under
          which P&U S.p.A.: (i) received rights to initiate registration of the
          non-registered Shares of Miravant which are held by P&U S.p.A.; (ii)
          received rights to participate in certain registrations initiated by
          Miravant or other shareholders of Miravant; and (iii) agreed not to
          transfer the 400,000 Shares which P&U S.p.A. received on July 7, 1994
          for one year unless certain conditions are met.

     (b)  PDT, Inc. $10,000,000 Common Stock and Warrants Offering Investment
          Agreement, dated as of August 31, 1994, by and between PDT and
          Pharmacia, Inc., under which Pharmacia, Inc. received the right to
          initiate registration of the non-registered Shares of PDT which are
          held by Pharmacia, Inc. and to participate in certain registrations
          initiated by PDT and/or other shareholders of PDT (the "1994 Stock
          Purchase Agreement").

     (c)  PDT Warrant, dated as of August 31, 1994, in which Pharmacia, Inc. was
          granted a warrant to purchase up to 41,667 Shares (pre-split) of PDT
          for the price of $12.00 per share (pre-split) (the "Warrant").

         The foregoing discussion is qualified in its entirety by reference to
the Stock Purchase Agreement, the 1994 Stock Purchase Agreement, and the Warrant
which were filed as exhibits to the Original Schedule 13Ds, each of which is
incorporated herein by reference.

ITEM 7.  MATERIAL TO BE FILED AS EXHIBITS


Exhibit No.         Exhibit Description
- -----------         -------------------
A                   Stock Purchase Agreement, dated as of July 7, 1995, by and
                    between PDT and Pharmacia S.p.A. (incorporated by reference
                    from Exhibit B to the report on Schedule 13D, dated July 7,
                    1995, filed by P&U AB with respect to Shares of Miravant)





<PAGE>


CUSIP Number: 69329P103                                           Page 13 of 20




B                   PDT, Inc. $10,000,000 Common Stock and Warrants Offering
                    Investment Agreement, dated as of August 31, 1994, by and
                    between PDT and Pharmacia, Inc.(incorporated by reference
                    from Exhibit B to the report on Schedule 13D, dated July 7,
                    1995, filed by P&U S.p.A. with respect to Shares of
                    Miravant)

C                   PDT Warrant, dated as of August 31, 1994, in which
                    Pharmacia, Inc. was granted a warrant to purchase up to
                    41,667 Shares (pre-split) of PDT for the price of $12.00 per
                    share (pre-split).(incorporated by reference from Exhibit C
                    to the report on Schedule 13D, dated July 7, 1995, filed by
                    P&U S.p.A. with respect to Shares of Miravant)

D                   P&U Proposed Term Sheet 

E                   Miravant Proposed Term Sheet

F                   Joint Filing Agreement




<PAGE>

CUSIP Number: 69329P103                                           Page 14 of 20



                                    SIGNATURE

         After reasonable inquiry and to the best of our knowledge and belief,
we certify that the information set forth in this statement is true, complete
and correct.

Dated:  December 1, 1998

                                   THE PHARMACIA & UPJOHN COMPANY


                                   By:  /s/ Don  W. Schmitz  
                                      ------------------------------------------
                                        Title: Secretary



                                   PHARMACIA & UPJOHN S.p.A.


                                   By:  /s/ Robert J. Little  
                                      ------------------------------------------
                                        Title: Managing Director



                                   PHARMACIA & UPJOHN AB


                                   By:  /s/ Goran A. Ando 
                                      ------------------------------------------
                                        Title: Executive Vice President



                                   PHARMACIA & UPJOHN INTERNATIONAL N.V.


                                   By:  /s/ Wim Kuiper
                                      ------------------------------------------
                                        Title: Director



                                   PHARMACIA & UPJOHN, INC.


                                   By:  /s/ Don  W. Schmitz  
                                      ------------------------------------------
                                        Title: Secretary

<PAGE>


CUSIP Number: 69329P103                                           Page 15 of 20



                                   SCHEDULE I

         Name, Business Address, Principal Occupation or Employment and
Citizenship of all Directors and Executive Officers of Pharmacia & Upjohn
S.p.A.:


Board of Directors
- ------------------

Maurizio Premoli
Pharmacia & Upjohn S.p.A.
via Robert Koch 1.2
20152 Milan Italy
Citizenship:  Italy

Francesco Radaelli
Pharmacia & Upjohn S.p.A.
via Robert Koch 1.2
20152 Milan Italy
Citizenship:  Italy

Emanuele Barie
Pharmacia & Upjohn S.p.A.
via Robert Koch 1.2
20152 Milan Italy
Citizenship:  Italy


Executive Officers
- ------------------

Toni Weitzberg
President
Pharmacia & Upjohn AB
Lindhagensatan 133
S-112 87 Stockholm  Sweden
Citizenship:  Sweden

Robert J. Little
Managing Director
Pharmacia & Upjohn S.p.A.
via Robert Koch 1.2
20152 Milan Italy
Citizenship:  United States




<PAGE>


CUSIP Number: 69329P103                                           Page 16 of 20



                                   SCHEDULE II

         Name, Business Address, Principal Occupation or Employment and
Citizenship of all Directors and Executive Officers of The Pharmacia & Upjohn
Company:


Board of Directors
- ------------------

Fred Hassan
President and CEO
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Richard T. Collier
Senior Vice President and General Counsel
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Christopher J. Coughlin
Executive Vice President and Chief Financial Officer
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States


Executive Officers
- ------------------

Fred Hassan
President and CEO
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Goran A. Ando, M.D.
Executive Vice President
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship: Sweden





<PAGE>


CUSIP Number: 69329P103                                           Page 17 of 20



Richard T. Collier
Senior Vice President and Assistant Secretary
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Timothy G. Rothwell
Executive Vice President
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Christopher J. Coughlin
Executive Vice President
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Robert G. Thompson
Senior Vice President and Controller
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States




<PAGE>


CUSIP Number: 69329P103                                           Page 18 of 20



                                  SCHEDULE III

         Name, Business Address, Principal Occupation or Employment and
Citizenship of all Directors and Executive Officers of Pharmacia & Upjohn, Inc.:


Board of Directors:
- -------------------

Gustaf Douglas
Chairman, Investment AB Latour
Biblioteksgatan 12
S-103 88 Stockholm, Sweden
Citizenship: Sweden

Fred Hassan
President and CEO, Pharmacia & Upjohn, Inc.
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Olof Lund
Chairman, Enator AB
Lojtnantsgatan 21
S-115 93 Stockholm Sweden
Citizenship:  Sweden

C. Steven McMillan
President and COO, Sara Lee Corporation
Suite 4600
Three First National Plaza
70 W. Madison
Chicago, IL  60602
Citizenship: United States

Richard H. Brown
CEO, Cable & Wireless plc
124 Theobalds Road
London, England  WC1X8RX
Citizenship: United States





<PAGE>


CUSIP Number: 69329P103                                           Page 19 of 20



M. Kathryn Eickhoff
President, Eickhoff Economics
Suite 400
510 LaGuardia Place
New York, NY  10012
Citizenship:  United States

R.L. Berthold Lindqvist
President & CEO, Gambro AB
Magistratsvagen 16
S-220 10 Lund Sweden
Citizenship: Sweden

Bengt I. Samuelsson
Professor, Karolinska Institutet
Scheele Laboratory
Department of Medicine Biochemistry & Biophysics
Doktorsringen 9, A3
S-171 77 Stockholm, Sweden
Citizenship: Sweden

Frank C. Carlucci
Chairman, The Carlyle Group
Suite 220S
1001 Pennsylvania Avenue, N.W.
Washington, DC  20004-2505
Citizenship:  United States

J. Soren Gyll - Chairman
Chairman of the Board of Directors, Pharmacia & Upjohn, Inc.
AB Volvo
Kungstradgarden
S-103 95 Stockholm Sweden
Citizenship:  Sweden

William U. Parfet
Co-Chairman, MPI Research
54943 N. Main Street
Mattawan, MI  49071
Citizenship:  United States

Ulla B. Reinius
President, Finansfakta R. AB
Sibyllegatam 5
S-I14 51 Stockholm Sweden
Citizenship:  Sweden





<PAGE>


CUSIP Number: 69329P103                                          Page 20 of 20


Executive Officers:
- -------------------

Fred Hassan
President and CEO
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Goran A. Ando, M.D.
Executive Vice President and President, Research and Development
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship: Sweden

Richard T. Collier
Senior Vice President and General Counsel
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Timothy G. Rothwell
Executive Vice President and President, Pharmaceutical Operations
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Christopher J. Coughlin
Executive Vice President and Chief Financial Officer
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

Robert G. Thompson
Senior Vice President and Chief Accounting Officer
95 Corporate Drive
Bridgewater, NJ  08807
Citizenship:  United States

<PAGE>

                                 EXHIBIT INDEX


Exhibit No.         Exhibit Description
- -----------         -------------------
10.1                Stock Purchase Agreement, dated as of July 7, 1995, by and
                    between PDT and Pharmacia S.p.A. (incorporated by reference
                    from Exhibit B to the report on Schedule 13D, dated July 7,
                    1995, filed by P&U AB with respect to Shares of Miravant)

10.2                PDT, Inc. $10,000,000 Common Stock and Warrants Offering
                    Investment Agreement, dated as of August 31, 1994, by and
                    between PDT and Pharmacia, Inc.(incorporated by reference
                    from Exhibit B to the report on Schedule 13D, dated July 7,
                    1995, filed by P&U S.p.A. with respect to Shares of
                    Miravant)

10.3                PDT Warrant, dated as of August 31, 1994, in which
                    Pharmacia, Inc. was granted a warrant to purchase up to
                    41,667 Shares (pre-split) of PDT for the price of $12.00 per
                    share (pre-split).(incorporated by reference from Exhibit C
                    to the report on Schedule 13D, dated July 7, 1995, filed by
                    P&U S.p.A. with respect to Shares of Miravant)

99.1                P&U Proposed Term Sheet 

99.2                Miravant Proposed Term Sheet

99.3                Joint Filing Agreement







                                   EXHIBIT D

                                       Project Phosphate
                                           Term Sheet

TERM LOAN
- --------------------------------------------------------------------------------

ISSUER:                  Phos ("Phos" or the "Company").

LENDER:                  Phate ("Phate" or the "Lender").

ISSUE:                   $15 million delayed draw term loan (the "Term Loan").

USE OF PROCEEDS:         General corporate purposes.

MATURITY:                5 years from the date of initial drawdown.

DRAWDOWN:                The Term Loan can be drawn upon during the first week
                         of each period noted as follows:


                               Period               Maximum Draw Amount
                         -----------------      ---------------------------
                               1Q '99                  $3.75 million
                               2Q '99                  $3.75 million
                               3Q '99                  $3.75 million
                               4Q '99                  $3.75 million


INTEREST RATE:           The portion of the Term Loan that has been drawn down 
                         will bear interest at the prevailing Prime Rate.

REPAYMENT:               The Term Loan shall be repayable by the Borrower at
                         maturity in cash or in common stock, at the sole option
                         of Phos. If Phos chooses to repay the Term Loan in
                         common stock, the price will be based upon the average
                         closing bid price of Phos's common stock for the 10
                         trading days preceding the date of the conversion.

Strategic Plan:          Prior to entering into the term loan agreement, the
                         Company shall present to Lender a detailed three year
                         plan (the "Strategic Plan") that contains items to be
                         agreed upon by Phos and Phate, to include, but not
                         limited to, a financial budget, staffing requirements,
                         research and development plans and timelines. Actions
                         and decisions by the Company shall remain in accordance
                         with the Strategic Plan.



                                       1

<PAGE>





OPTIONAL PREPAYMENTS:    The Company may prepay the Term Loan at any time in
                         cash, in whole or in part, without premium, with
                         minimum payments of $3 million.

MANDATORY PREPAYMENTS:   The following amounts shall be paid to Phate to reduce
                         the balance and the commitment of the Term Loan:

                         i.    50% of the net proceeds of debt or equity
                               offerings, private or public; 
                         ii.   100% of the net proceeds of asset sales; or 
                         iii.  75% of cash flows in excess of $5 million per 
                               year.

COLLATERAL:              The Term Loan will be secured through a security
                         interest in substantially all of Phos's tangible and
                         intangible property, including intellectual property
                         rights.

                         Comprehensive representations and warranties, including
                         (without limitation):

REPRESENTATIONS
  AND WARRANTIES:
                         i.   Corporate existence and power;
                         ii.  Corporate authority to execute the Term Loan,
                              validity, no conflict with charter documents, laws
                              or agreements and no governmental approvals;
                         iii. Financial   information;   
                         iv.  No material adverse change in the financial
                              condition, or business of the Borrower and its
                              subsidiaries taken as a whole, from the date of
                              the most recent audited financial statements prior
                              to the execution of the credit agreement;
                         v.   No material undisclosed litigation; 
                         vi.  Filing and payment of all material taxes (subject
                              to customary appeal and protest rights);
                         vii. Compliance with ERISA and environmental laws and
                              margin regulations;
                         viii.Compliance with FDA and related regulations.


                                      -2-

<PAGE>


CONDITIONS PRECEDENT:    Conditions precedent to the execution of the definitive
                         Term Loan agreement (the "Definitive Agreement") will
                         be those that are customary for facilities of this
                         type, including (without limitation):

                         i.   All documents and agreements signed and delivered;
                         ii.  Satisfactory completion of due diligence with
                              respect to the corporate, tax and legal structure
                              of the Borrower and its subsidiaries;
                         iii. Reduction to a valid and binding written agreement
                              of the current agreements with the hedge funds;
                         iv.  Compliance with all covenants.

                         Conditions precedent to each drawdown will be those
                         that are customary for facilities of this type,
                         including (without limitation):

                         i.   True and correct representations and warranties;
                         ii.  No default;  
                         iii. Satisfactory review of any legal issues;
                         iv.  Usual evidence of corporate power and authority
                              and good standing, including board resolutions and
                              legal opinions;
                         v.   No material default under the Strategic Plan.



                                       -3-



<PAGE>


AFFIRMATIVE COVENANTS:   High yield covenants, including, but not limited to:
                         delivery of financial statements, reports, accountants'
                         letters, officers' certificates and other information
                         requested by Lender; payment of other obligations;
                         continuation of business and maintenance of existence
                         and material rights and privileges; compliance with
                         laws and material contractual obligations; maintenance
                         of property and insurance; maintenance of books and
                         records; right of the Lender to inspect property and
                         books and records; notices of defaults, litigation and
                         other material events; and agreement to grant security
                         interests in after-acquired property.

NEGATIVE COVENANTS:      High yield covenants, including, but not limited to
                         limitations on: indebtedness; liens; guarantees;
                         mergers, acquisitions, consolidations, liquidation and
                         dissolutions; dividends and other payments in respect
                         of capital stock; investments, loans and advances
                         modifications of debt instruments; capital
                         expenditures, transactions with affiliates;
                         dispositions of assets and leasebacks; changes in
                         fiscal year; negative pledge clauses; and changes in
                         line of business.

EVENTS OF DEFAULT:       Material breach of the Strategic Plan; material
                         inaccuracy of representations and warranties; violation
                         of covenants; cross-default; cross-acceleration;
                         bankruptcy; and a change of control.

ASSIGNMENTS:             The Lender will be permitted to assign and participate
                         the Term Loan without restriction.

EXPENSES:                Lender's expenses shall be paid by the Issuer.

DOCUMENTATION:           To be acceptable to Phate.


                                      -4-

<PAGE>



WARRANTS
- --------------------------------------------------------------------------------

TERM:                    5 years from the time the Warrant is issued.

EXERCISE PRICE:          At a 40% premium to the average closing bid price of
                         Phos's common stock for the 10 trading days preceding
                         the date of the issue of the Warrant.

COVERAGE:                The Company shall issue to Phate upon each drawdown of
                         the Term Loan a warrant to purchase 60,000 common
                         shares of Phos (the "Warrant").


EQUITY
- --------------------------------------------------------------------------------

CONVERSION OF            Concurrent with the signing of the Definitive
  COMMITTED ONCOLOGY     Agreement, the $[Confidential Treatment Requested] of
  R&D FUNDING AND        Phate's committed research and development funding for
  AMD  MILESTONE         Phos's oncology program and the $[Confidential
  PAYMENTS:              Treatment Requested] in potential milestones for the
                         AMD program to be paid by Phate in accordance with the
                         current licensing agreement shall be converted into an
                         equity investment in Phos. The conversions into equity
                         will be based on the average of the closing bid prices
                         for Phos's common stock for the ten days preceding when
                         the amounts become payable. Proceeds are to be used for
                         general corporate purposes.


AMENDMENTS TO CURRENT AGREEMENTS
- --------------------------------------------------------------------------------

                               [Confidential Treatment Requested]








OPHTHALMIC MARKETING
  RIGHTS:                The Agreement will be modified to grant Phate worldwide
                         marketing rights to the Product for all current and
                         future indications in the ophthalmic field.

CLINICAL/REGULATORY:     Phate will assume control of all clinical and
                         regulatory aspects of the joint ophthalmic programs.

MANUFACTURING RIGHTS:    The Agreement will be amended to extend the license to
                         Phate to include manufacturing rights to the Product;
                         current supply agreements between parties will be
                         amended to allow Phate to assume control of bulk
                         manufacturing and finishing of the Product.


CONTROL OF DEVICE
  SUPPLY CONTRACT:       Phate will enter into a contract with Iridex for supply
                         of the PhotoPoint light delivery device in place of the
                         current PhotoPoint supply agreement.


                                      -5-

                                    EXHIBIT E


TERM SHEET

Issue:                   $24 million delayed drawdown.

Drawdown:                $6 million per quarter beginning Q1 1999.

Strategic Plan:          Designate the use of the funds per a
                         proposed financial budget. Remove all requirements
                         regarding Strategic Plan compliance throughout the term
                         of the loan.

Optional Prepayments:    Additionally, if repaid in whole, then repayment can be
                         in Phos' Common Stock at Phos' discretion based on the
                         average of the closing bid prices for the 10 trading
                         days preceding the prepayment date.

Mandatory
Prepayment:              Modified as follows:
                         i.   50% of equity of debt offerings, public or 
                              private, made after Year 2000; 
                         ii.  100% of sale of Company; or
                         iii. 50% of net cash flows in excess of $10 million per
                              year.

Collateral:              Secured by tangible property rights.

Conditions Precedent:    No adjustment to hedge fund agreement prior to the 
                         hedge fund resolution.

Negative Covenants:      Too restrictive.

Events of Default:       Should be limited to bankruptcy or inability to operate
                         as a going concern.

EQUITY

Conversion of
Committed Oncology       
R&D Funding and
Payments:                Conversion to equity at a 30% premium of the average of
                         the closing bid prices for the 10 trading days 
                         preceding the signing of the Definitive Agreement.




CONFIDENTIAL                       -1-




<PAGE>


AMENDMENTS TO CURRENT AGREEMENTS

Royalties:               No adjustment to royalties.

Ophthalmic Marketing:    Only includes SnET2 and Phos conducts Phase I and Phase
                         II clinical studies in U.S. and Phos receives end of 
                         Phase II milestones.

Clinical/Regulatory:     Phate to control all clinical and regulatory aspects of
                         Phase III clinical studies and files NDA in Phate's 
                         name. Phos keeps control of current ophthalmology IND. 

Manufacturing Rights:    Phos to provide bulk product at 150 gram levels. Phate
                         to take responsibility of finished product immediately
                         and responsibility for bulk product beyond 150 gram
                         levels.

Control of Device 
Supply Contract:         Phos and Phate to enter into a three-way marketing and
                         commercial supply agreement.

Warrants:                Phos to determine the right number of warrants.

Other Items:             Possible stand-off provision until 2002 unless mutually
                         agreed to by Phos and Phate management.

                         Full transition of AMD Phase III clinical and 
                         regulatory responsibilities at conclusion of complete 
                         enrollment of clinical trial. Phos maintains
                         representation on key project teams until NDA approval.



CONFIDENTIAL                           -2-


                                   EXHIBIT F

                             JOINT FILING AGREEMENT


                  Each of the Reporting Persons hereby agrees to make this joint
filing pursuant to Rule 13d-1(f) of the Exchange Act of 1934.



Dated:  December 1, 1998

                                   THE PHARMACIA & UPJOHN COMPANY


                                   By:  /s/ Don  W. Schmitz  
                                      ------------------------------------------
                                        Title: Secretary



                                   PHARMACIA & UPJOHN S.p.A.


                                   By:  /s/ Robert J. Little  
                                      ------------------------------------------
                                        Title: Managing Director



                                   PHARMACIA & UPJOHN AB


                                   By:  /s/ Goran A. Ando 
                                      ------------------------------------------
                                        Title: Executive Vice President



                                   PHARMACIA & UPJOHN INTERNATIONAL N.V.


                                   By:  /s/ Wim Kuiper
                                      ------------------------------------------
                                        Title: Director



                                   PHARMACIA & UPJOHN, INC.


                                   By:  /s/ Don  W. Schmitz  
                                      ------------------------------------------
                                        Title: Secretary




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