MIRAVANT MEDICAL TECHNOLOGIES
10-Q, 1999-05-17
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 10-Q


|X|      QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
         SECURITIES EXCHANGE ACT OF 1934



                  For the quarterly period ended March 31, 1999

                                       OR

|_|      TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
         SECURITIES EXCHANGE ACT OF 1934

                         Commission File Number: 0-25544
                          Miravant Medical Technologies
- --------------------------------------------------------------------------------
             (Exact name of Registrant as specified in its charter)


         Delaware                                  77-0222872
- --------------------------------------------------------------------------------
(State or other jurisdiction of              (IRS Employer Identification No.)
incorporation or organization)

                336 Bollay Drive, Santa Barbara, California 93117
- --------------------------------------------------------------------------------
          (Address of principal executive offices, including zip code)

                               (805) 685-9880
- --------------------------------------------------------------------------------
              (Registrant's telephone number, including area code)


         Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
Registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days. Yes |X| No |_|

         Indicate  the  number of  shares  outstanding  of each of the  issuer's
classes of common stock, as of the latest practicable date.

         Class                                  Outstanding at May 10, 1999
Common Stock, $.01 par value                           17,971,516








                                TABLE OF CONTENTS


                          PART I. FINANCIAL INFORMATION
                                                                            Page

Item 1.  Consolidated Financial Statements

         Consolidated balance sheets as of March 31, 1999 and
           December 31, 1998...................................................3
         Consolidated statements of operations for the three months ended
           March 31, 1999 and 1998.............................................4
         Consolidated statements of cash flows for the three months ended
           March 31, 1999 and 1998.............................................5
         Notes to consolidated financial statements............................6

Item 2.  Management's Discussion and Analysis of Financial
           Condition and Results of Operations.................................9

Item 3.  Qualitative and Quantitative Disclosures About Market Risk...........15

                           PART II. OTHER INFORMATION

Item 6.  Exhibits and Reports on Form 8-K.....................................15

         Signatures ..........................................................16




ITEM 1.  CONSOLIDATED FINANCIAL STATEMENTS

                          MIRAVANT MEDICAL TECHNOLOGIES
                           CONSOLIDATED BALANCE SHEETS
<TABLE>
<CAPTION>
<S>                                                                             <C>                    <C>    


                                                                                      March 31,           December 31,
                                                                                        1999                  1998
                                                                                --------------------   ------------------
                                                                                     (Unaudited)
                                    Assets
Current assets:
   Cash and cash equivalents...............................................     $      13,644,000      $     11,284,000
   Investments in short-term marketable securities.........................             7,250,000                    --
   Accounts receivable.....................................................             2,563,000             3,182,000
   Prepaid expenses and other receivables..................................             2,218,000               792,000
                                                                                --------------------   ------------------
Total current assets.......................................................            25,675,000            15,258,000

Property, plant & equipment:
   Vehicles................................................................                28,000                28,000
   Furniture and fixtures..................................................             1,638,000             1,720,000
   Equipment...............................................................             5,161,000             5,180,000
   Leasehold improvements..................................................             4,550,000             4,232,000
   Capital lease equipment.................................................               184,000               184,000
                                                                                --------------------   ------------------
                                                                                       11,561,000            11,344,000
   Accumulated depreciation and amortization...............................            (6,232,000)           (5,514,000)
                                                                                --------------------   ------------------
                                                                                        5,329,000             5,830,000

Investments in affiliates..................................................             2,102,000             1,512,000
Loan to affiliate, net of reserve..........................................                    --                    --
Patents and other assets...................................................             1,145,000             1,210,000
                                                                                --------------------   ------------------
                                                                                
Total assets...............................................................     $      34,251,000      $     23,810,000
                                                                                ====================   ==================

Liabilities and shareholders' equity Current liabilities:
   Accounts payable........................................................     $       3,144,000      $      3,541,000
   Accrued payroll and expenses............................................               779,000               583,000
                                                                                  ------------------     ----------------
Total current liabilities..................................................             3,923,000             4,124,000

Shareholders' equity:
   Common stock, 50,000,000 shares authorized;  17,915,302 and 16,080,054 
     shares issued and outstanding at March 31, 1999 and
     December 31, 1998, respectively.......................................           150,514,000           135,989,000
   Notes receivable from officers..........................................              (442,000)           (1,525,000)
   Deferred compensation...................................................            (2,413,000)           (2,896,000)
   Accumulated other comprehensive loss....................................            (2,374,000)           (2,964,000)
   Accumulated deficit.....................................................          (114,957,000)         (108,918,000)
                                                                                --------------------   ------------------
Total shareholders' equity.................................................            30,328,000            19,686,000
                                                                                --------------------   ------------------
                                                                                
Total liabilities and shareholders' equity.................................     $      34,251,000      $     23,810,000
                                                                                ====================   ==================


See accompanying notes.

</TABLE>


                          MIRAVANT MEDICAL TECHNOLOGIES
                      CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (Unaudited)
<TABLE>
<CAPTION>
<S>                                                                     <C>                    <C>   



                                                                               Three months ended March 31,
                                                                                 1999                   1998
                                                                        --------------------   ---------------------
Revenues:
   Grants, licensing and royalty revenues............                    $       2,412,000     $           635,000
                                                                        --------------------   ---------------------
Total revenues.......................................                            2,412,000                 635,000

Costs and expenses:
   Research and development..........................                            6,352,000               6,318,000
   Selling, general and administrative...............                            1,977,000               3,047,000
   Loss in affiliate.................................                              288,000                 454,000
                                                                        --------------------   ---------------------
Total costs and expenses.............................                            8,617,000               9,819,000

Loss from operations.................................                           (6,205,000)             (9,184,000)

Interest and other income (expense):
   Interest and other income.........................                              166,000               1,268,000
   Interest expense..................................                                   --                  (1,000)
                                                                        --------------------   ---------------------
Total net interest and other income..................                              166,000               1,267,000
                                                                        --------------------   ---------------------

Net loss.............................................                    $      (6,039,000)    $        (7,917,000)
                                                                        ====================   =====================
Net loss per share - basic and diluted...............                    $           (0.35)    $             (0.56)
                                                                        ====================   =====================
Shares used in computing net loss per share..........                           17,071,169              14,103,532
                                                                        ====================   =====================


See accompanying notes.
</TABLE>



                          MIRAVANT MEDICAL TECHNOLOGIES
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (Unaudited)
<TABLE>
<CAPTION>
<S>                                                                     <C>                    <C>    


                                                                               Three months ended March 31,
Operating activities:                                                            1999                   1998
                                                                        --------------------   ---------------------
    Net loss...........................................................  $      (6,039,000)     $       (7,917,000)
    Adjustments to reconcile net loss to net cash used by operating
    activities:
       Depreciation and amortization...................................            767,000                 586,000
       Amortization of deferred compensation...........................            483,000                 646,000
       Loss on sale of property, plant and equipment...................             25,000                      --
       Reserve for loan receivable from affiliate......................            288,000                      --
       Stock awards....................................................             80,000                      --
       Changes in operating assets and liabilities:
          Accounts receivable..........................................            476,000                 (96,000)
          Prepaid expenses and other assets............................         (1,230,000)                (74,000)
          Accounts payable and accrued payroll and expenses............           (201,000)             (1,665,000)
                                                                        --------------------   ---------------------   
    Net cash used in operating activities..............................         (5,351,000)             (8,520,000)

Investing activities:
    Purchases of marketable securities.................................         (7,250,000)            (12,008,000)
    Sales of marketable securities.....................................                 --               9,921,000
    Investments in affiliates..........................................                 --                 454,000
    Purchases of property, plant and equipment.........................           (278,000)               (653,000)
                                                                        --------------------   ---------------------
    Net cash used in investing activities..............................         (7,528,000)             (2,286,000)

Financing activities:
    Proceeds from issuance of Common Stock, less issuance costs........         18,648,000               2,670,000
    Purchases of Common Stock..........................................                 --              (8,968,000)
    Payments of executive officer notes................................                 --              (1,161,000)
    Adjustments to executive officer notes.............................          1,083,000                      --
    Payments of capital lease obligations..............................                 --                 (12,000)
    Payments of loan to affiliate......................................           (288,000)                     --
    Payments for price protection under the Amended Securities 
       Agreement.......................................................         (4,204,000)                     --
                                                                        --------------------   ---------------------
    Net cash provided by (used in) financing activities................         15,239,000             (7,471,000)

    Net increase (decrease) in cash and cash equivalents...............          2,360,000             (18,277,000)
    Cash and cash equivalents at beginning of period...................         11,284,000              55,666,000      
                                                                        --------------------   ---------------------
    Cash and cash equivalents at end of period.........................  $      13,644,000      $       37,389,000
                                                                        ====================   =====================

Supplemental disclosures:
    State taxes paid...................................................  $              --      $           59,000
                                                                        ====================   =====================
    Interest paid......................................................  $              --      $            1,000
                                                                        ====================   =====================

See accompanying notes.

</TABLE>



                          MIRAVANT MEDICAL TECHNOLOGIES
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1.   Basis of Presentation

     The information  contained herein has been prepared in accordance with Rule
     10-01 of Regulation  S-X. The  information  at March 31, 1999,  and for the
     three month periods  ended March 31, 1999 and 1998,  is  unaudited.  In the
     opinion of management,  the information reflects all adjustments  necessary
     to make the results of operations for the interim  periods a fair statement
     of such operations.  All such adjustments are of a normal recurring nature.
     Interim results are not necessarily  indicative of results for a full year.
     For a presentation including all disclosures required by generally accepted
     accounting  principles,  these  financial  statements  should  be  read  in
     conjunction with the audited consolidated financial statements for the year
     ended  December  31, 1998  included in the  Miravant  Medical  Technologies
     Annual  Report  on  Form  10-K  filed  with  the  Securities  and  Exchange
     Commission.

2.   Comprehensive Income (Loss)

     Effective  January 1, 1998,  the Company  adopted SFAS No. 130,  "Reporting
     Comprehensive Income". SFAS No. 130 established new rules for the reporting
     and  display of  comprehensive  income  and its  components;  however,  the
     adoption  of SFAS  No.  130 had no  impact  on the  Company's  net  loss or
     shareholders' equity. Under SFAS No. 130, the Company has elected to report
     other  comprehensive  income,  which includes unrealized gains or losses on
     available-for-sale securities, in the statement of shareholders' equity.

     For the three  months  ended  March 31, 1999 and 1998,  comprehensive  loss
     amounted to approximately $5.5 million and $7.9 million,  respectively. The
     difference between net loss and comprehensive loss relates to the change in
     the unrealized loss or gain the Company recorded for its available-for-sale
     securities on its investment in its affiliate Xillix.

3.   Per Share Data

     Basic loss per common  share is computed  by  dividing  the net loss by the
     weighted average shares outstanding during the period. Diluted earnings per
     share  reflects the  potential  dilution  that would occur if securities or
     other contracts to issue common stock were exercised or converted to common
     stock. Since the effect of the assumed exercise of common stock options and
     other convertible securities was anti-dilutive,  basic and diluted loss per
     share as presented on the  consolidated  statements of  operations  are the
     same.

4.   Reclassifications

     Certain reclassifications have been made to the 1998 consolidated financial
     statements to conform to the periods presented.

5.   Loan to Affiliate

     In April 1998, the Company entered into a revolving  credit  agreement with
     its  affiliate,  Ramus,  pursuant to which the  Company,  at the request of
     Ramus,  shall  from  time to time  make  loans  to  Ramus  in an  aggregate
     outstanding  principal  amount not  exceeding at any one time $2.0 million.
     The  unpaid  principal  amount of the  loans,  which are to be used to fund
     Ramus' clinical trials and operating costs,  accrues interest at a variable
     rate (7.25% as of March 31,  1999) based on the  Company's  bank rate,  and
     matures in March 2000.  The loans are evidenced by a promissory  note,  the
     balance of which is convertible  under certain  circumstances at the option
     of the Company into shares of Ramus stock. As of March 31, 1999,  Ramus had
     borrowed  the entire $2.0  million  available  under the  revolving  credit
     agreement. The Company has established a reserve for the entire outstanding
     balance of the loan receivable at March 31, 1999, which is included in loss
     in affiliate in the consolidated statements of operations.

6.   Shareholders' Equity

     Collaboration with Pharmacia & Upjohn

     In January 1999,  the Company and Pharmacia & Upjohn,  Inc. and Pharmacia &
     Upjohn S.p.A.,  which involve these entities and certain other wholly owned
     subsidiaries  or  Pharmacia  & Upjohn,  entered  into an Equity  Investment
     Agreement  pursuant  to which  Pharmacia  & Upjohn has  purchased  from the
     Company  1,136,533  shares of the Company's  Common Stock, or Common Stock,
     for an aggregate purchase price of $19.0 million, or $16.71 per share. This
     price includes a premium of approximately 20% over the ten (10) day average
     per share closing price of the Common Stock through  January 14, 1999.  The
     Company and certain  wholly owned  subsidiaries  of Pharmacia & Upjohn have
     also entered into certain other  agreements,  including a Credit  Agreement
     which will  extend to the Company up to $22.5  million in credit,  which is
     subject to certain limitations and restrictions,  to be used to support the
     Company's  ophthalmology,  oncology and other development programs, as well
     as for general corporate purposes. In connection with the extension of this
     credit, Pharmacia & Upjohn, or its wholly owned subsidiaries,  will receive
     a total of up to 360,000 warrants to purchase Common Stock of Miravant. The
     exercise  price of each warrant will be equal to 140% of the average of the
     closing  bid  prices  of the  Common  Stock for the ten (10)  trading  days
     immediately   preceding  the  borrowing   request  for  the  related  loan.
     Additionally,  the  Company  and  Pharmacia  & Upjohn  have  amended  their
     existing  ophthalmology and oncology  development and license agreements to
     eliminate  future  cost  reimbursements  for  oncology  and urology and any
     future milestone payments in age-related macular degeneration or AMD. Under
     the Credit  Agreement,  upon its  initial  borrowing  and until the loan is
     fully paid off, the Company  will be required to meet certain  affirmative,
     negative and financial covenants.

     Shareholders' Equity

     In  accordance  with  the  amended  Securities  Purchase  Agreement  or the
     Amendment  Agreement  dated  June  30,  1998,  the  Company  fulfilled  its
     obligations  related to  112,500  shares  subject  to the price  protection
     provisions  for the January 1,  February  1, and March 1, 1999  measurement
     dates.  The Company  elected to pay the  purchasers  cash and Common Stock,
     with the cash  portion  amounting  to $1.2  million,  $1.3 million and $1.7
     million,  respectively.  The remainder of the price protection  obligations
     for those measurement dates was paid in the form of shares of Common Stock,
     which  amounted  to 199,746  shares,  207,072  shares and  282,178  shares,
     respectively.   The  original  900,000  shares,  less  the  337,500  shares
     repurchased by the Company,  and a corresponding number of warrants are now
     released  from the lock-up  provisions  under the Amendment  Agreement.  In
     addition,  under the Amendment Agreement,  in March 1999 the Company issued
     an additional  450,000  warrants to the  purchasers at an exercise price of
     $35.00 per share. The Company has now satisfied all of its price protection
     obligations under the Amendment  Agreement and, as such, the Company has no
     further price protection  obligations  under this agreement to any of these
     parties.

7.   Notes Receivable from Officers

     In December  1997,  the  Compensation  Committee  of the Board of Directors
     recommended and  subsequently  approved equity loans in varying amounts for
     the  Company's  Chief  Executive  Officer,  President  and Chief  Financial
     Officer.  The notes,  which accrue interest at a fixed rate of 5.8% and are
     payable  in five  years,  were  awarded  specifically  for the  purpose  of
     exercising options to acquire the Company's Common Stock and for paying the
     related  option   exercise   price  and  payroll   taxes.   The  notes  are
     collateralized by the underlying shares acquired upon exercise.  In January
     1999,  the Company  adjusted  the loan  balances to reflect a change in the
     amount of payroll taxes due. Payroll taxes of $961,000, originally withheld
     and paid related to the option  exercises,  will be refunded to the Company
     by  the  applicable   taxing  agencies  and  has  been  included  in  other
     receivables.  As of March 31, 1999 the  executive  loan  balances have been
     reduced  accordingly  and are  classified  as a reduction of  shareholders'
     equity.

8.   Short-Term Loan to Officer

     In August 1998, the Company made a short-term  loan to its Chief  Executive
     Officer.  The note accrues interest at a fixed rate of 5.5% and matures one
     year  from the date of  issuance.  Currently,  the note has an  outstanding
     balance of $296,000 plus accrued interest.

9.   Subsequent Event

     In April 1999, in accordance  with the Credit  Agreement  entered into with
     Pharmacia  & Upjohn,  the  Company  requested  to  draw-down  the first two
     quarterly loans for a total of $7.5 million.  In addition,  under the terms
     of the Credit Agreement and in connection with each draw-down,  the Company
     is obligated  to issue to  Pharmacia & Upjohn a certain  number of warrants
     based on the amount  borrowed,  which provide for the purchase of one share
     of Common Stock per warrant.  In  connection  with the first two  quarterly
     loan  draw-downs,  the Company issued 120,000 warrants at an exercise price
     of $11.87 per warrant share.



ITEM 2. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS

     The  following   discussion   should  be  read  in  conjunction   with  the
consolidated  financial  statements and notes thereto.  This Quarterly Report on
Form 10-Q may be deemed to include forward looking statements within the meaning
of Section 27A of the  Securities  Act of 1933 and Section 21E of the Securities
Exchange  Act of 1934 that involve risk and  uncertainty,  including  financial,
clinical,  business environment and trend projections.  Although we believe that
our expectations are based on reasonable  assumptions,  we can give no assurance
that our goals will be achieved.  The important  factors that could cause actual
results to differ materially from those in the forward looking statements herein
include,  without limitation,  the current stage of development of both Miravant
and our  products,  the timing and  uncertainty  of results of both research and
regulatory  processes,  the extensive  government  regulation  applicable to our
business,  the unproven safety and efficacy of our drug and device products, our
significant  additional  financing  requirements,  the  volatility  of our stock
price,  the  uncertainty  of future  capital  funding,  the  highly  competitive
environment of the  international  pharmaceutical  and medical device industries
and  the  presence  of  a  number  of  competitors  with  significantly  greater
financial,  technical and other resources and extensive operating histories, our
potential  exposure to product  liability or recall,  uncertainties  relating to
patents  and other  intellectual  property,  including  whether  we will  obtain
sufficient protection or competitive advantage therefrom, uncertainties relating
to our  ability  to  successfully  complete  our Year 2000  initiatives  and our
dependence  upon a  limited  number of key  personnel  and  consultants  and our
significant  reliance upon our  collaborative  partners for achieving our goals,
and other factors  detailed in our Annual Report on Form 10-K for the year ended
December 31, 1998.

General

     Since our inception,  we have been principally  engaged in the research and
development of drugs and medical device products for use in PhotoPoint(TM),  our
proprietary  technologies for photodynamic  therapy.  We have been  unprofitable
since our founding  and have  incurred a  cumulative  net loss of  approximately
$115.0 million as of March 31, 1999. We expect to continue to incur substantial,
and possibly  increasing,  operating  losses for the next  several  years due to
continued  and  increased  spending on research and  development  programs,  the
funding of preclinical  studies,  clinical trials and regulatory  activities and
the costs of manufacturing and administrative activities.

     Our revenues  primarily  reflect income earned from  licensing  agreements,
grants and royalties  from device  product  sales.  To date, we have received no
revenue from the sale of drug  products,  and we are not  permitted to engage in
commercial  sales of drugs or devices  until such time,  if ever,  as we receive
requisite  regulatory  approvals.  As a  result,  we do  not  expect  to  record
significant product sales until such approvals are received.

     Until we commercialize our product(s), we expect revenues to continue to be
attributable to licensing  agreements,  grants and royalties from device product
sales. We anticipate that future revenues and results of operations may continue
to fluctuate  significantly  depending on, among other  factors,  the timing and
outcome of applications  for regulatory  approvals,  our ability to successfully
manufacture,  market and distribute our drug products and device products and/or
the  restructuring  or  establishment  of  collaborative  arrangements  for  the
manufacturing, marketing and distribution of some of our products. We anticipate
our operating  activities will result in substantial net losses for several more
years.

     In June 1998,  we amended the  development  and funding  provisions  of our
previously executed 1995 SnET2 development and license agreements with Pharmacia
& Upjohn,  Inc. and some of its subsidiaries,  which together are referred to as
Pharmacia & Upjohn in this report. Under the amended ophthalmology agreement, we
were to conduct all  preclinical  studies and U.S.  clinical trials and would be
reimbursed  by  Pharmacia  & Upjohn  for all  out-of-pocket  expenses  incurred,
provided  that the trials  were  conducted  in  accordance  with the  agreement.
Pharmacia  &  Upjohn  was  to  conduct  all  international  clinical  trials  in
ophthalmology. We also amended our oncology, urology and dermatology development
and license agreement to return to us the rights for SnET2 in dermatology and to
provide for the quarterly funding  of $2.5 million for eight quarters for use in
our oncology and urology  programs.  Subsequently,  in January  1999, we entered
into  an  Equity  Investment  Agreement,   which  also  amended  the  June  1998
ophthalmology,  oncology and urology  agreements with Pharmacia & Upjohn.  Under
this 1999 equity agreement, Pharmacia & Upjohn purchased 1,136,533 shares of our
Common Stock for an aggregate purchase price of $19.0 million,  which represents
the  acceleration  of the  remaining  six $2.5  million  quarterly  payments for
oncology and urology and two future milestone  payments for age-related  macular
degeneration,  or AMD,  under the  amended  June 1998  development  and  license
agreements. Also in January 1999, under a separate Credit Agreement, Pharmacia &
Upjohn has  extended  to us up to $22.5  million in credit,  which is subject to
certain  limitations and requirements,  in the form of up to six quarterly loans
of $3.75  million  each to be used to support our  ophthalmology,  oncology  and
other development programs, as well as for general corporate purposes.

     During the third quarter of 1998 and in connection  with the 1998 amendment
of the  Pharmacia  & Upjohn  agreements,  we  implemented  a cost  restructuring
program designed to focus our resources on our core development programs,  which
emphasize  large  potential  market   opportunities  and  unmet  medical  needs.
Additionally,  the  program  was  designed  to  utilize  the cost  reimbursement
components  of the  1998  amended  Pharmacia  &  Upjohn  agreements  as  well as
streamline  administrative  activities,  reduce  overhead  costs  and  eliminate
positions that were not central to our core  development  programs.  In February
1999,  based on the January  1999  amended  Pharmacia & Upjohn  development  and
license  agreements,  we refined our use of  resources  to utilize the change in
cost  reimbursement  from Pharmacia & Upjohn while  maintaining  our development
programs.  We will  continue to evaluate the use of our resources as our funding
provisions change and as opportunities present themselves.

     We are currently  conducting clinical trials in oncology and ophthalmology.
In dermatology,  we are investigating the development of topical formulations of
our  photoselective  drugs.  Based upon the outcome of these studies and various
economic  and  development  factors,   including  cost,  reimbursement  and  the
available  alternative  therapies,  we may or may not elect to  further  develop
PhotoPoint  procedures in oncology,  ophthalmology,  dermatology or in any other
indications.

Year 2000

     The Year 2000 issue is the result of computer  programs being written using
two  digits  rather  than four to  define  the  applicable  year.  Our  computer
equipment   and  software  and  devices  with  embedded   technology   that  are
time-sensitive  may recognize a date using "00" as the year 1900 rather than the
year 2000.  This could  result in a system  failure or  miscalculations  causing
disruptions of operations, such as:

     *    A  temporary  inability  to  process  accounting,  payroll,  database,
          network   and   software   transactions;    Possible   disruption   of
          environmental,   lighting,   security  controls  and  other  corporate
          equipment;
     *    A temporary  inability to process clinical and preclincal  testing and
          data; and
     *    Loss of telephone  and related  voicemail  and internet  messages,  in
          addition to other similar normal business activities.

     We have undertaken various initiatives intended to ensure that our computer
equipment and software will function  properly with respect to dates in the Year
2000 and thereafter. The term "computer equipment and software" includes systems
that are commonly thought of as Information Technology or IT systems,  including
accounting,  data processing and telephone/PBX  systems and other  miscellaneous
systems.  It also  includes  systems  that  are not  commonly  thought  of as IT
systems, such as alarm systems, fax machines, air conditioning units, internally
developed software and other  miscellaneous  systems.  Based upon our efforts to
date, we believe that certain of the computer  equipment and software we use may
require  replacement  or  modification.  Utilizing  both  internal  and external
resources  to identify  and assess  needed Year 2000  remediation,  we currently
anticipate  that our  Year  2000  identification,  assessment,  remediation  and
testing  efforts,  which began in February  1998,  will be completed by June 30,
1999. We estimate that as of March 31, 1999, we had completed  approximately 75%
of the initiatives that we believe will be necessary to fully address  potential
Year 2000 issues relating to our computer equipment software and non-IT systems.
The projects  comprising the remaining 25% of the initiatives are in process and
are  expected to be completed on or about June 30,  1999.  The  following  table
describes the Year 2000  initiatives as well as our progress and the anticipated
completion dates as of March 31, 1999:

<TABLE>
<CAPTION>
<S>                                                                          <C>                  <C>   

                                                                                Expected
Year 2000 Initiatives                                                        Completion Date         Percent
                                                                                                    Complete
                                                                             -----------------    ---------------

     Initial IT system identification......................................       10/98                   100%
     Initial IT system assessment..........................................       11/98                   100%
     Remediation regarding central system issues...........................        6/99                    75%
     Testing regarding central system issues...............................        6/99                    15%
     Identification, assessment, remediation and testing regarding desktop
           and individual system issues....................................        6/99                    75%

     Identification regarding non-IT system issues.........................       10/98                   100%
     Assessment regarding non-IT system issues.............................       11/98                   100%
     Remediation regarding non-IT system issues............................        6/99                    75%
     Testing regarding non-IT system issues................................        6/99                    15%
     
</TABLE>

     We are in the process of  communicating  with our  significant  vendors and
service  providers  and  strategic  partners  to  determine  the extent to which
interfaces with such entities are vulnerable to Year 2000 issues and whether the
products and services  utilized by such entities are Year 2000  compliant.  This
process is expected to be completed in June 1999.

     We believe that the cost of our Year 2000  efforts,  as well as those costs
related  to Year 2000  issues of third  parties,  are  expected  to  approximate
$250,000.  As of March 31, 1999, we had not incurred any external  costs related
to our  Year  2000  efforts.  Other  non-Year  2000 IT  efforts  have  not  been
materially  delayed or impacted by Year 2000  initiatives.  We presently believe
that the Year 2000 issue will not pose significant  operational problems for us.
However,  if all Year 2000  issues are not  properly  identified,  the Year 2000
issue may  materially  adversely  impact our results of  operations or adversely
affect our relationships with vendors,  or others.  Additionally,  the Year 2000
issues of other  entities may have a material  adverse  impact on our systems or
results of operations.

Results of Operations

     The following  table provides a summary of our revenues for the three month
periods ended March 31, 1999 and 1998:

<TABLE>
<CAPTION>
<S>                                                       <C>                   <C>   


  ------------------------------------------------------------------------------------------

                                                         Three months ended March 31,
  Consolidated Revenues                                   1999                  1998
  ------------------------------------------------------------------------------------------
  Grants and contracts........................            $   122,000           $   141,000
  Royalties...................................                 62,000                49,000
  License.....................................              2,228,000               445,000
  ------------------------------------------------------------------------------------------
  Total revenue...............................            $ 2,412,000           $   635,000              
  ------------------------------------------------------------------------------------------

</TABLE>

     Revenues.  Our revenues  increased from $635,000 for the three months ended
March 31, 1998 to $2.4 million for the three months ended March 31, 1999.

     For three months ended March 31, 1999, we recorded revenues of $2.2 million
for the specific  reimbursement  of  out-of-pocket  or direct costs  incurred in
preclinical  studies  and Phase III  clinical  trials  in  ophthalmology.  These
reimbursements  were  recorded in  accordance  with the January 1999 amended and
restated  ophthalmology  and oncology  development and license agreement entered
into with  Pharmacia & Upjohn.  For the three months  ended March 31,  1998,  we
recorded  revenues of $445,000  for the specific  reimbursement  of oncology and
Phase I/II ophthalmology  clinical program costs in conjunction with the license
agreement  entered  into in July 1995 with  Pharmacia  &  Upjohn.  The  revenues
recorded for ophthalmology  cost  reimbursement  may fluctuate  depending on the
direct costs incurred and Pharmacia & Upjohn's level of involvement in the Phase
III clinical trials.

     The level of  license,  grant  and  royalty  income is likely to  fluctuate
materially  from period to period and in the future  depending  on the amount of
preclinical  and clinical costs incurred and/or  reimbursed,  the achievement of
milestones  and the  extent of  development  activities  under the  amended  and
restated  ophthalmology  and oncology  development  and license  agreements with
Pharmacia & Upjohn,  the amount of grant  income  awarded and  expended  and the
amount of device products sold by Laserscope. Under the 1999 amended Pharmacia &
Upjohn  development  and license  agreements  for  ophthalmology,  oncology  and
urology,  we will only be  reimbursed  for the  specific  costs for  preclinical
studies and clinical trials in ophthalmology and we will no longer be reimbursed
for any oncology  and urology  program  costs,  as the  quarterly  reimbursement
payments for these costs were  accelerated in connection  with the $19.0 million
equity  investment  made by  Pharmacia & Upjohn  under the  January  1999 Equity
Investment Agreement. The Laserscope license agreement, which provides royalties
on the sale of our previously designed device products, terminated in April 1999
and no further royalties are expected to be received.

     Research and  Development.  Our research and  development  expenses of $6.4
million for the current  period were  consistent  with the $6.3  million for the
three months ended March 31, 1998. Research and development expenses incurred in
1999 and 1998 related primarily to:

     *    The  costs  associated  with  drug and  device  manufacturing  and the
          screening,   treatment  and   monitoring   of  qualified   individuals
          participating  in clinical  trials for AMD and prostate  cancer during
          1999;
     *    The costs  associated with the screening,  treatment and monitoring of
          qualified  individuals  participating in clinical trials in AMD and in
          other oncology programs during 1998;
     *    The  preparation  of  the   documentation   for  clinical  trials  and
          regulatory filings; and
     *    The  preclinical  studies and  development  work  associated  with the
          development  of  existing  and new drug  compounds,  formulations  and
          clinical programs.

     Future  research and  development  expenses may fluctuate  depending on the
impact of our cost  restructuring  program  implemented  in September  1998, the
level of Pharmacia & Upjohn's  involvement in our Phase III AMD clinical trials,
continued  expenses  incurred in our preclinical  studies and clinical trials in
other  ophthalmology  and  oncology  programs,  and  costs  associated  with the
purchase of raw  materials  and supplies for the  production of devices and drug
for  use  in  preclinical   studies  and  clinical  trials,  the  pharmaceutical
manufacturing  scale-up  to  expanded  commerical  levels and  expansion  of our
research  and  development  programs,  which  includes the  increased  hiring of
personnel,  the continued  expansion of preclinical  studies and clinical trials
and the development of new drug compounds and formulations.

     Selling,   General   and   Administrative.   Our   selling,   general   and
administrative  expenses  decreased  to $2.0  million for the three months ended
March 31, 1999 from $3.0 million for the three months ended March 31, 1998.  The
overall decrease in selling,  general and administrative  expenses for the first
three months of 1999 compared to the same period in 1998 is primarily due to:

     *    A decrease in costs  associated with  professional  services  received
          from financial consultants, attorneys and public and media relations;
     *    A decrease  in payroll  and  overhead  costs due to the  reduction  of
          administrative  and  corporate   personnel  in  conjunction  with  our
          September 1998 cost restructuring program; and
     *    A  decrease  in  compensation  expense  associated  with  options  and
          warrants issued to consultants and expense  recorded for the executive
          option loans.

     Future selling,  general and administrative expenses are expected to remain
constant due to our September 1998 cost restructuring program.  Conditions which
may influence  these  expenses are increased  support  required for research and
development  activities,   continuing  corporate  development  and  professional
services,  compensation  expense  associated with stock options and warrants and
financial consultants and general corporate matters.

     Loss in Investment in Affiliate.  In connection  with the $2.0 million line
of credit we have provided to our affiliate, Ramus, we have recorded $288,000 as
expense, which represents a reserve on the final $250,000 paid out on the credit
line plus accrued  interest.  The  $454,000  recorded for the three months ended
March 31, 1998  represents a reduction,  based on 100% of Ramus'  losses for the
respective  period, of the $2.0 million equity investment made to Ramus in 1996.
The future losses recorded with respect to Ramus will be limited to reserves for
accrued interest, as the line of credit has been fully utilized and reserved for
and the investment balance reduced to zero as of March 31, 1999.

     Interest and Other Income.  Interest and other income  decreased  from $1.3
million for the three  months  ended  March 31,  1998 to $166,000  for the three
months  ended March 31,  1999.  The  decrease for the first three months of 1999
compared to the same period in 1998 is directly  related to the  decrease in the
levels of cash and marketable  securities earning interest.  The level of future
interest  and  other  income  will  primarily  be  subject  to the level of cash
balances we maintain from period to period.

     Interest  Expense.  The level of interest  expense  incurred  for the first
three months of 1999 and 1998 was not material.  Interest  expense will increase
during  1999  and the  level  of  increase  will be  subject  to the  amount  of
borrowings under the Pharmacia & Upjohn Credit Agreement.

     We do not believe that  inflation has had a material  impact on our results
of operations.

Liquidity and Capital Resources

     Since  inception  through March 31, 1999, we have  accumulated a deficit of
approximately  $115.0 million and expect to continue to incur  substantial,  and
possibly  increasing,  operating  losses  for the next  several  years.  We have
financed our operations primarily through private placements of Common Stock and
Preferred Stock,  private  placements of convertible notes and short-term notes,
our initial public offering,  Pharmacia & Upjohn's purchases of Common Stock and
a secondary  public  offering.  As of March 31, 1999, we have received  proceeds
from the sale of equity securities and convertible notes of approximately $200.5
million.

     In  September  and  October  1997,  we  entered  into a  private  placement
offering,  which was  subsequently  amended with respect to certain  purchasers,
which provided net proceeds to Miravant of approximately  $68.2 million.  During
1998, under the price protection and repurchase  provisions of these agreements,
we issued an additional  2,444,380 shares of Common Stock,  repurchased  337,500
shares of Common Stock for $16.9  million and paid $8.6  million.  Additionally,
during the first quarter of 1999, we completed our price protection  obligations
through the payment of $4.2  million and the issuance of 688,996  shares  Common
Stock and the  issuance of an  additional  450,000  warrants to purchase  Common
Stock at an  exercise  price of $35.00  per share.  As such,  we have no further
obligation  to  these  purchasers  under  the  price  protection  or  repurchase
provisions of the Securities Purchase Agreements and the amendments thereto.

     In  December  1997,  the  Board of  Directors  authorized  a  Common  Stock
repurchase program allowing for the repurchase of up to 750,000 shares of Common
Stock.  This  750,000  share  repurchase  authorization  was in  addition to and
superseded the repurchase program authorized in July 1996, which allowed for the
repurchase of up to 600,000  shares of Common Stock.  For the three months ended
March 31, 1999 we had no stock  repurchases and for the three months ended March
31, 1998 we  repurchased  280,000  shares at a cost of $9.0 million.  All shares
repurchased were retired.

     In  January  1999,  we entered  into an Equity  Investment  Agreement  with
Pharmacia & Upjohn whereby Pharmacia & Upjohn purchased  1,136,533 shares of our
Common Stock for an aggregate purchase price of $19.0 million, which represented
the acceleration of the oncology and urology reimbursement  payments and the two
future milestone  payments for AMD. Pharmacia & Upjohn will also extend to us up
to $22.5  million in credit  over the next two years to be used to  support  our
ophthalmology,  oncology and other development  programs, as well as for general
corporate  purposes.  In April 1999,  in  accordance  with the Credit  Agreement
entered into with  Pharmacia & Upjohn,  the Company  requested to draw-down  the
first two quarterly  loans for a total of $7.5 million.  In addition,  under the
terms of the Credit Agreement and in connection with each draw-down, the Company
is obligated to issue  Pharmacia & Upjohn a certain  number of warrants based on
the amount borrowed. The exercise price of each warrant will be equal to 140% of
the  average of the  closing  bid  prices of the  Common  Stock for the ten (10)
trading days  immediately  preceding the borrowing  request for the related loan
and provides for the purchase of one share of our Common  Stock.  In  connection
with the first two quarterly loan  draw-downs,  we issued 120,000 warrants at an
exercise price of $11.87 per warrant share.

     In April  1998,  we entered  into a  revolving  credit  agreement  with our
affiliate,  Ramus,  which  provided  Ramus with the ability to borrow up to $2.0
million.  As of March 31, 1999, we have provided the entire loan of $2.0 million
to Ramus. In addition,  in accordance with the 1996 equity  investment in Ramus,
we had an  exclusive  option to  purchase  the  remaining  shares of Ramus for a
specified amount under certain terms and conditions. The option expired March 3,
1999 and we elected not to exercise the option.

     In February  1998,  we agreed to guaranty a term loan in the amount of $7.6
million  from a bank to a  director  of  ours at the  time.  In June  1998,  the
director did not stand for  re-election  on the Board of Directors.  The loan is
due and  payable on July 31,  1999,  or sooner  upon an event of default  and is
secured by all of the  individual's  shares of our Common Stock. We also granted
the bank a security  interest in an account  maintained  at the bank and agreed,
upon an  event  of  default,  to  purchase  the  loan  from the bank for a price
generally equal to the then outstanding principal,  plus accrued interest,  fees
and costs.  If we  purchase  the loan,  we have the option to acquire all of the
individual's shares at a price equal to 50% of the 20-day average closing price,
net of the loan repayment. The individual also agreed to certain restrictions on
the  sale of such  shares.  Under  the  loan  agreement  and the  guaranty,  the
individual and Miravant are subject to the  maintenance  of specified  financial
and other covenants.

     For the three  months ended March 31, 1999 and 1998,  we required  cash for
operations of $5.4 million and $8.5 million,  respectively. The decrease for the
three months  ended March 31, 1999  compared to the three months ended March 31,
1998 was primarily due to a decrease in operating activities associated with the
our cost  restructuring  program  implemented  in September  1998. For the three
months ended March 31, 1999, net cash for financing  activities provided us with
$15.2 million as compared to net cash used by our  financing  activities of $7.5
million for the three months  ended March 31,  1998.  The increase for the three
months ended March 31, 1999 is  primarily  related to our $19.0  million  Equity
Investment Agreement entered into with Pharmacia & Upjohn in January 1999, which
was offset by the  satisfaction  of all of our remaining  obligations  under the
price  protection  provisions of the Amendment  Agreement.  For the three months
ended March 31, 1998 the primary use of cash for financing activities related to
our  repurchase of Common Stock at a cost of $9.0 million under our Common Stock
repurchase program.

     We invested a total of $8.8  million in property  and  equipment  from 1996
through March 31, 1999.  During 1998, we entered into a new lease  agreement for
an additional facility,  for which we have the ability to sublease. We expect to
continue  to purchase  property  and  equipment  in the future as we continue to
expand our preclinical, clinical and research and development activities as well
as the buildout and expansion of laboratories and office space.

     Our future capital requirements will depend on numerous factors including:

     *    The progress and magnitude of our research and  development  programs,
          including preclinical studies and clinical trials;
     *    The time involved in obtaining regulatory approvals;
     *    The cost involved in filing and maintaining patent claims;
     *    Competitor and market conditions;
     *    Investment opportunities;
     *    Our ability to establish and maintain collaborative arrangements;
     *    The  level of  Pharmacia  &  Upjohn's  involvement  in our  Phase  III
          ophthalmology clinical trials;
     *    The cost of manufacturing  scale-up and the cost and  effectiveness of
          commercialization activities and arrangements; and
     *    Our  ability to obtain  grants to  finance  research  and  development
          projects.

     Our ability to generate  substantial  funding to continue  our research and
development   activities,   preclinical   studies   and   clinical   trials  and
manufacturing,  scale-up,  administrative  activities and additional  investment
opportunities is subject to a number of risks and  uncertainties and will depend
on numerous factors including:

     *    Our  ability to raise  funds in the future  through  public or private
          financings, collaborative arrangements or from other sources;
     *    The  potential  for equity  investments,  collaborative  arrangements,
          license agreements or development or other funding programs with us in
          exchange for manufacturing, marketing, distribution or other rights to
          products developed by us; and
     *    Our ability to maintain our existing collaborative arrangements.

     We can not guarantee that  additional  funding will be available to us when
needed.  If it is not,  we will be  required  to  scale  back our  research  and
development programs, preclinical studies and clinical trials and administrative
activities  and our  business  and  financial  results  and  condition  would be
materially adversely affected.


ITEM 3.QUALITATIVE AND QUANTITATIVE DISCLOSURES ABOUT MARKET RISK

     The  following  discussion  about  our  market  risk  disclosures  involves
forward-looking  statements.  Actual results could differ  materially from those
projected  in the  forward-looking  statements.  We are  exposed to market  risk
related to changes in  interest  rates.  The risks  related to foreign  currency
exchange  rates  are   immaterial  and  we  do  not  use  derivative   financial
instruments.

     From  time  to  time,  we  maintain  a  portfolio  of  highly  liquid  cash
equivalents  maturing in three months or less as of the date of purchase.  Given
the short-term nature of these investments,  and as of March 31, 1999 we have no
borrowings outstanding, we are not subject to significant interest rate risk.





                           PART II. OTHER INFORMATION




ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

                  (a)      Exhibits.
                           See Exhibit Index on page 18.

                  (b)      Reports on Form 8-K.
                           Form 8-K dated January 15, 1999,  Other Events - Item
                           5:  announcing  that the Company had entered  into an
                           Equity   Investment   Agreement   and  other  related
                           agreements with Pharmacia & Upjohn.





                                   SIGNATURES

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed in its behalf by the
undersigned thereunto duly authorized.


                          Miravant Medical Technologies




Date:    May 14, 1999                       By:/s/ John M. Philpott
- -----    ------------                       -----------------------
                                               John M. Philpott
                                               Chief Financial Officer
                                               (on behalf of the Company and as
                                               Principal Financial Officer and
                                               Principal Accounting Officer)




                                INDEX TO EXHIBITS
<TABLE>
<CAPTION>
<S>             <C>                                                                                         <C>    

                                                                                                            Incorporating
Exhibit                                                                                                     Reference
Number                                                 Description                                          (if applicable)
3.1             Certificate of Amendment of the Restated  Certificate of  Incorporation  of the Registrant
                filed with the Delaware Secretary of State on September 12, 1998.                           [E][3.1]
3.2             Certificate of Amendment of the Restated  Certificate of  Incorporation  of the Registrant  [C][3.11]
                filed with the Delaware Secretary of  State on  July 24, 1995.
3.3             Restated  Certificate of Incorporation of the Registrant filed with the Delaware Secretary  [B][3.1]
                of State on December 14, 1994.
3.4             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.2]
                the Delaware Secretary of State on March 17, 1994.
3.5             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.3]
                the Delaware Secretary of State on October 7, 1992.
3.6             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.4]
                the Delaware Secretary of State on November 21, 1991.
3.7             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.5]
                the Delaware Secretary of State on September 27, 1991.
3.8             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.6]
                the Delaware Secretary of State on December 20, 1989.
3.9             Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.7]
                the Delaware Secretary of State on August 11, 1989.
3.10            Certificate of Amendment of the Certificate of  Incorporation of the Registrant filed with  [A][3.8]
                the Delaware Secretary of State on July 13, 1989.
3.11            Certificate of Incorporation of the Registrant filed with the Delaware  Secretary of State  [A][3.9]
                on June 16, 1989.
3.12            Amended and Restated Bylaws of the Registrant.                                              [E][3.12]
4.1             Specimen Certificate of Common Stock.                                                       [B][4.1]
4.2             Form of Convertible Promissory Note.                                                        [A][4.3]
4.3             Form of Indenture.                                                                          [A][4.4]
4.4             Special Registration Rights Undertaking.                                                    [A][4.5]
4.5             Undertaking Agreement dated August 31, 1994.                                                [A][4.6]
4.6             Letter Agreement dated March 10, 1994.                                                      [A][4.7]
4.7             Form of $10,000,000 Common Stock and Warrants Offering Investment Agreement.                [A][4.8]
4.8             Form of $55 Common Stock Purchase Warrant.                                                  [D][4.1]
4.9             Form of $60 Common Stock Purchase Warrant.                                                  [D][4.2]
4.10            Form of $35 Amended and Restated Common Stock Purchase Warrant.                             [F][4.1]
4.11            Form of Additional $35 Common Stock Purchase Warrant.                                       [F][4.2]
4.12            Warrant to Purchase  10,000 Shares of Common Stock between the  Registrant  and Charles S.  [G][4.12]
                Love.*
10.1            Amendment  No.  7  dated  as of  January  1,  1999 to  Employment  Agreement  between  the
                Registrant and Gary S. Kledzik.*
10.2            Amendment  No.  12 dated  as of  January  1,  1999 to  Employment  Agreement  between  the
                Registrant and David E. Mai.*
10.3            Amendment  No.  4  dated  as of  January  1,  1999 to  Employment  Agreement  between  the
                Registrant and John M. Philpott.*
27.1            Financial Data Schedule.
</TABLE>

- -------------------------------------------

[A]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained  in the  Registrant's  Registration  Statement  on Form S-1
           (File No. 33-87138).
[B]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained  in  Amendment  No.  2  to  the  Registrant's  Registration
           Statement on Form S-1 (File No. 33-87138).
[C]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained in the  Registrant's  Form 10-Q for the quarter  ended June
           30, 1995, as amended on Form 10-Q/A dated  December 6, 1995 (File No.
           0-25544).
[D]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained  in the  Registrant's  Registration  Statement  on Form S-3
           (File No. 333-39905).
[E]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained  in the  Registrant's  Form  10-Q  for  the  quarter  ended
           September 30, 1998 (File No. 0-25544).
[F]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained in the Registrant's  Form 8-K dated June 30, 1998 (File No.
           0-25544).
[G]        Incorporated  by reference  from the exhibit  referred to in brackets
           contained in the  Registrant's  Form 10-Q for the quarter  ended June
           30, 1998 (File No. 0-25544).
[H]        Exhibit A-1 to this exhibit is  incorporated  by  reference  from the
           exhibit  referred to in the  Registrant's  Registration  Statement on
           Form S-1 (File No. 33-87138)
 *         Confidential  portions of this  exhibit have been deleted and filed
           separately with the  Commission  pursuant  to Rule  24b-2  under  the
           Securities Exchange Act of 1934.

 
 ===============================================================================
                     AMENDMENT NO. 7 TO EMPLOYMENT AGREEMENT
 ===============================================================================

     THIS AMENDMENT NO. 7 TO EMPLOYMENT  AGREEMENT (the "Amendment") is made and
entered into at Santa Barbara,  California, on the date hereinafter set forth by
and between Gary S. Kledzik,  Ph.D.  (hereinafter referred to as the "Employee")
and MIRAVANT MEDICAL TECHNOLOGIES,  a Delaware Corporation (hereinafter referred
to as the "Employer").

WHEREAS:

     A. The Employer and the  Employee  are parties to an  Employment  Agreement
effective as of December 31, 1989,  and  Amendments No. 1 through 6 thereto (the
"Employment Agreement").

     B. The parties  hereto wish to amend the  Employment  Agreement  in certain
respects.

     NOW,   THEREFORE,   in   consideration   of  the  premises,   promises  and
representations hereinafter contained, it is agreed as follows:

     1. Effective JANUARY 1, 1999, the section entitled EMPLOYEE COMPENSATION on
Exhibit A to the Employment Agreement is hereby amended to read as follows:

     EMPLOYEE COMPENSATION

     THREE HUNDRED TWENTY FIVE THOUSAND DOLLARS ($325,000) per annum.

     2. In all other  respects,  the  Employment  Agreement is hereby  ratified,
confirmed and approved in its entirety.






                             SIGNATURES ON NEXT PAGE




     IN WITNESS WHEREOF, the parties hereto have executed this Amendment on this
26th day of January, 1999.

                                             EMPLOYER:
                                             MIRAVANT MEDICAL TECHNOLOGIES
                                             a Delaware Corporation

                                             By:  /s/ David E. Mai          
                                                  ----------------          
                                                  David E. Mai
                                                  President

                                             EMPLOYEE:/s/ Gary S. Kledzik, Ph.D.
                                                      --------------------------
                                                      Gary S. Kledzik, Ph.D.




================================================================================
                    AMENDMENT NO. 12 TO EMPLOYMENT AGREEMENT
================================================================================



     THIS AMENDMENT NO. 12 TO EMPLOYMENT AGREEMENT (the "Amendment") is made and
entered into at Santa Barbara,  California, on the date hereinafter set forth by
and  between  DAVID E.  MAI  (hereinafter  referred  to as the  "Employee")  and
MIRAVANT MEDICAL TECHNOLOGIES,  a Delaware Corporation  (hereinafter referred to
as the "Employer").

WHEREAS:

     A. The Employer and the  Employee  are parties to an  Employment  Agreement
effective as of February 1, 1991,  and  Amendments No. 1 through 11 thereto (the
"Employment Agreement").

     B. The parties  hereto wish to amend the  Employment  Agreement  in certain
respects.

     NOW,   THEREFORE,   in   consideration   of  the  premises,   promises  and
representations hereinafter contained, it is agreed as follows:

     1. Effective JANUARY 1, 1999, the section entitled EMPLOYEE COMPENSATION on
Exhibit A to the Employment Agreement is hereby amended to read as follows:

     EMPLOYEE COMPENSATION

     TWO HUNDRED FIFTY THOUSAND DOLLARS ($250,000) per annum.

     2. In all other  respects,  the  Employment  Agreement is hereby  ratified,
confirmed and approved in its entirety.



                             SIGNATURES ON NEXT PAGE


     IN WITNESS WHEREOF, the parties hereto have executed this Amendment on this
26th day of January, 1999.

                                    EMPLOYER:     MIRAVANT MEDICAL TECHNOLOGIES
                                                  a Delaware Corporation
                                                              

                                    By:           /s/ Gary S. Kledzik, Ph.D. 
                                               -------------------------- 
                                                  Gary S. Kledzik, Ph.D.
                                                  C.E.O. and Chairman

                                    EMPLOYEE:     /s/ David E. Mai       
                                                  David E. Mai




================================================================================
                     AMENDMENT NO. 4 TO EMPLOYMENT AGREEMENT
================================================================================
         
     THIS AMENDMENT NO. 4 TO EMPLOYMENT  AGREEMENT (the "Amendment") is made and
entered into at Santa Barbara,  California, on the date hereinafter set forth by
and between JOHN M. PHILPOTT  (hereinafter  referred to as the  "Employee")  and
MIRAVANT MEDICAL TECHNOLOGIES,  a Delaware Corporation  (hereinafter referred to
as the "Employer").

WHEREAS:

     A. The Employer and the  Employee  are parties to an  Employment  Agreement
effective  as of March 20,  1995,  and  Amendments  No. 1 through 3 thereto (the
"Employment Agreement").

     B. The parties  hereto wish to amend the  Employment  Agreement  in certain
respects.

     NOW,   THEREFORE,   in   consideration   of  the  premises,   promises  and
representations hereinafter contained, it is agreed as follows:

     1. Effective JANUARY 1, 1999, the section entitled EMPLOYEE COMPENSATION on
Exhibit A to the Employment Agreement is hereby amended to read as follows:

     EMPLOYEE COMPENSATION

     ONE HUNDRED SEVENTY FIVE THOUSAND DOLLARS ($175,000) per annum.

     2. In all other  respects,  the  Employment  Agreement is hereby  ratified,
confirmed and approved in its entirety.




                            SIGNATUARES ON NEXT PAGE



     IN WITNESS WHEREOF, the parties hereto have executed this Amendment on this
26th day of January, 1999.

                                  EMPLOYER:  MIRAVANT MEDICAL TECHNOLOGIES
                                             a Delaware Corporation
                                            

                                  By:        /s/ Gary S. Kledzik, Ph.D. 
                                             Gary S. Kledzik, Ph.D.
                                             C.E.O. and Chairman

                                  EMPLOYEE:  /s/ John M. Philpott    
                                             John M. Philpott

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          THIS SCHEDULE  CONTAINS SUMMARY FINANCIAL  INFORMATION  EXTRACTED FROM
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