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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. 2 )*
Quadramed Corporation
---------------------
(Name of Issuer)
Common Stock, $.01 par value
----------------------------
(Title of Class of Securities)
74730W 10 1
--------------
(CUSIP Number)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 2 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | Oxford Bioscience Partners L.P. |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | Delaware Limited Partnership |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | PN |
- --------------------------------------------------------------------------------
Page 2 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 3 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | OBP Management L.P. |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | Delaware Limited Partnership |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | PN |
- --------------------------------------------------------------------------------
Page 3 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 4 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | Oxford Bioscience Partners (Bermuda) Limited Partnership |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | Bermuda Limited Partnership |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | PN |
- --------------------------------------------------------------------------------
Page 4 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 5 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | OBP Management (Bermuda) Limited Partnership |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | Bermuda Limited Partnership |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | PN |
- --------------------------------------------------------------------------------
Page 5 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 6 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | Edmund M. Olivier |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | United States |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | IN |
- --------------------------------------------------------------------------------
Page 6 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 7 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | Cornelius T. Ryan |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | United States |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | IN |
- --------------------------------------------------------------------------------
Page 7 of 15 Pages
<PAGE>
- ------------------------- ---------------------------
|CUSIP NO. 74730W 10 1 | 13G | Page 8 of 15 Pages |
| ----------- | | --- -- |
- ------------------------- ---------------------------
|--------|---------------------------------------------------------------------|
| 1 | NAME OF REPORTING PERSON |
| | S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON |
| | |
| | Alan G. Walton |
|--------|---------------------------------------------------------------------|
| 2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ] |
| | (b) [ ] |
| | |
|--------|---------------------------------------------------------------------|
| 3 | SEC USE ONLY |
| | |
|--------|---------------------------------------------------------------------|
| 4 | CITIZENSHIP OR PLACE OF ORGANIZATION |
| | |
| | United States |
|-----------------|--------|---------------------------------------------------|
| | 5 | SOLE VOTING POWER |
| | | 0 shares |
| NUMBER OF |--------|---------------------------------------------------|
| SHARES | 6 | SHARED VOTING POWER |
| BENEFICIALLY | | 201,439 shares |
| OWNED BY |--------|---------------------------------------------------|
| EACH | 7 | SOLE DISPOSITIVE POWER |
| REPORTING | | 0 shares |
| PERSON |--------|---------------------------------------------------|
| WITH | 8 | SHARED DISPOSITIVE POWER |
| | | 201,439 shares |
|------------------------------------------------------------------------------|
| 9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON |
| | |
| | 201,439 shares |
|--------|---------------------------------------------------------------------|
| 10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [ ] |
| | SHARES* |
| | |
|--------|---------------------------------------------------------------------|
| 11 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) |
| | 2.0% |
|--------|---------------------------------------------------------------------|
| 12 | TYPE OF REPORTING PERSON* |
| | IN |
- --------------------------------------------------------------------------------
Page 8 of 15 Pages
<PAGE>
NOTE: This Statement on Schedule 13G is being filed on behalf of (i)
Oxford Bioscience Partners L.P., a Delaware limited partnership; (ii) OBP
Management L.P., a Delaware limited partnership; (iii) Oxford Bioscience
Partners (Bermuda) Limited Partnership, a Bermuda limited partnership; (iv) OBP
Management (Bermuda) Limited Partnership, a Bermuda limited partnership; (v)
Edmund M. Olivier; (vi) Cornelius T. Ryan; and (vii) Alan G. Walton.
Item 1(a). Name of Issuer: Quadramed Corporation
--------------
Item 1(b). Address of Issuer's Principal Executive Offices:
-----------------------------------------------
80 E. Sir Francis Drake Blvd., Suite 2A, Larkspur, CA 94939
<TABLE>
<CAPTION>
Item 2(a) Item 2(b) Item 2(c)
Citizenship or Place
Name of Person Filing Address of Organization
<S> <C> <C>
Oxford Bioscience Partners L.P. Oxford Bioscience Partners Delaware
("OBP") 315 Post Road West
Westport, CT 06880
OBP Management L.P. ("OBP Oxford Bioscience Partners Delaware
Management"), the general 315 Post Road West
partner of OBP and OBP Adjunct Westport, CT 06880
Oxford Bioscience Partners Richmond House Bermuda
(Bermuda) Limited Partnership Par-la-Ville Road
("OBP Bermuda') Hamilton, Bermuda
OBP Management (Bermuda) Limited Richmond House Bermuda
Partnership ("OBP Management Par-la-Ville Road
Bermuda"), the general Hamilton, Bermuda
partner of OBP Bermuda
Edmund M. Olivier, a general Oxford Bioscience Partners United States
partner of OBP Management and 650 Town Center Drive
OBP Management Bermuda Costa Mesa, California 92626
Cornelius T. Ryan, a general Oxford Bioscience Partners United States
partner of OBP Management and 315 Post Road West
OBP Management Bermuda Westport, CT 06880
Alan G. Walton, a general partner Oxford Bioscience Partners United States
of OBP Management and OBP 315 Post Road West
Management Bermuda Westport, CT 06880
</TABLE>
Item 2(d). Title of Class of Securities: Common Stock, $.01 par value.
----------------------------
Item 2(e). CUSIP Number: 74730W 10 1
------------
Item 3. If this statement is filed pursuant to Rules 13d-1(b), or
13d-2(b), check whether the person filing is a:
---------------------------------------------------------
Page 9 of 15 pages
<PAGE>
(a) [ ] Broker or Dealer registered under Section 15 of
the Securities Exchange Act of 1934 (the "Act").
(b) [ ] Bank as defined in Section 3(a)(6) of the Act.
(c) [ ] Insurance Company as defined in Section 3(a)(19)
of the Act.
(d) [ ] Investment Company registered under Section 8 of
the Investment Company Act of 1940.
(e) [ ] Investment Adviser registered under Section 203
of the Investment Advisers Act of 1940.
(f) [ ] Employee Benefit Plan, Pension Fund which is
subject to the provisions of the Employee
Retirement Income Security Act of 1974 or
Endowment Fund; see Rule 13d-1(b)(1)(ii)(F) of
the Act.
(g) [ ] Parent Holding Company, in accordance with Rule
13d-1(b)(ii)(G) of the Act.
(h) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(H)
of the Act.
None of the above.
Item 4. Ownership.
---------
(a) Amount Beneficially Owned: As of December 31, 1997, each
of the following is the owner of record of the number of
shares of Common Stock set forth next to his, her or its
name:
OBP: 65,468 shares
OBP Management: 0 shares
OBP Bermuda: 18,465 shares
OBP Management Bermuda: 0 shares
Mr. Olivier: 0 shares
Mr. Ryan: 0 shares
Mr. Walton: 0 shares
By virtue of their relationship as affiliated limited
partnerships, whose sole general partners share individual
general partners, OBP and OBP Bermuda may be deemed to share
voting power and the power to direct the disposition of the
shares of Common Stock which each partnership owns of record.
Hence, OBP and OBP Bermuda may be deemed to own beneficially an
aggregate of 83,933 shares of Common Stock. Also, OBP and OBP
Bermuda own presently exerciseable warrants to purchase 91,655
shares and 25,851 shares of Common Stock, respectively.
Therefore, OBP and OBP Bermuda may be deemed to own beneficially
an additional 117,506 shares of Common Stock. Messrs. Ryan,
Walton and Olivier are general partners of both OBP Management,
the general partner of OBP and OBP Bermuda Management, the
general partner OBP Bermuda. Therefore, each of Messrs. Ryan,
Walton and Olivier may be deemed to own beneficially the shares
and warrants held by OBP and OBP Bermuda.
Page 10 of 15 pages
<PAGE>
(b) Percent of Class:
OBP: 2.0%
OBP Management: 2.0%
OBP Bermuda: 2.0%
OBP Management Bermuda: 2.0%
Mr. Olivier: 2.0%
Mr. Ryan: 2.0%
Mr. Walton: 2.0%
The foregoing percentages are calculated based on the 10,195,753
shares of Common Stock reported to be outstanding as of Ocotber
31, 1997 in the Quarterly Report on Form 10-Q/A of Quadramed
Corporation for the quarter ended September 30, 1997, as
adjusted pursuant to Rule 13d-3 (d)(1) of the Act.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
OBP: 0 shares
OBP Management: 0 shares
OBP Bermuda: 0 shares
OBP Management Bermuda: 0 shares
Mr. Olivier: 0 shares
Mr. Ryan: 0 shares
Mr. Walton: 0 shares
(ii) shared power to vote or to direct the vote:
OBP: 201,439 shares
OBP Management: 201,439 shares
OBP Bermuda: 201,439 shares
OBP Management Bermuda: 201,439 shares
Mr. Olivier: 201,439 shares
Mr. Ryan: 201,439 shares
Mr. Walton: 201,439 shares
Page 11 of 15 pages
<PAGE>
(iii) sole power to dispose or to direct the disposition
of:
OBP: 0 shares
OBP Management: 0 shares
OBP Bermuda: 0 shares
OBP Management Bermuda: 0 shares
Mr. Olivier: 0 shares
Mr. Ryan: 0 shares
Mr. Walton: 0 shares
(iv) shared power to dispose or to direct the
disposition of:
OBP: 201,439 shares
OBP Management: 201,439 shares
OBP Bermuda: 201,439 shares
OBP Management Bermuda: 201,439 shares
Mr. Olivier: 201,439 shares
Mr. Ryan: 201,439 shares
Mr. Walton: 201,439 shares
Each of OBP, OBP Management, OBP Bermuda, OBP Management
Bermuda, Mr. Olivier, Mr. Ryan and Mr. Walton expressly
disclaims beneficial ownership of any shares of Common Stock of
Quadramed Corporation, except any shares held directly of
record.
Item 5. Ownership of Five Percent or Less of a Class.
--------------------------------------------
If this statement is being filed to report the fact that as of
the date hereof the reporting person has ceased to be the
beneficial owner of more than five percent of the class of
securities, check the following: [X]
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
---------------------------------------------------------------
Not applicable.
Item 7. Identification and Classification of the Subsidiary Which
Acquired the Security Being Reported on by the Parent Holding
Company.
-------------------------------------------------------------
Not applicable.
Item 8. Identification and Classification of Members of the Group.
---------------------------------------------------------
Not applicable. OBP, OBP Management, OBP Bermuda, OBP Management
Bermuda, Mr. Olivier, Mr. Ryan and Mr. Walton expressly disclaim
membership in a "group" as defined in Rule 13d-1(b)(ii)(H) of
the Act.
Item 9. Notice of Dissolution of Group.
------------------------------
Not applicable.
Page 12 of 15 pages
<PAGE>
Item 10. Certification.
-------------
Not applicable. This statement on Schedule 13G is not filed
pursuant to Rule 13d-1(b).
Page 13 of 15 pages
<PAGE>
Signature
After reasonable inquiry and to the best of his, her or its knowledge
and belief, each of the undersigned certifies that the information set forth in
this statement is true, complete and correct. We also hereby agree to file this
statement jointly pursuant to the agreement set forth as Exhibit 1 to our
initial Schedule 13G filing.
Dated: February 13th, 1998
OXFORD BIOSCIENCE PARTNERS L.P.
By: OBP Management L.P., its general partner
By: /s/ Cornelius T. Ryan
-------------------------------------
General Partner
OXFORD BIOSCIENCE PARTNERS (BERMUDA)
LIMITED PARTNERSHIP
By: OBP Management (Bermuda) Limited
Partnership, its general partner
By: /s/ Cornelius T. Ryan
-------------------------------------
General Partner
OBP MANAGEMENT L.P.
By: /s/ Cornelius T. Ryan
------------------------------------------
General Partner
OBP MANAGEMENT (BERMUDA) LIMITED PARTNERSHIP
By: /s/ Cornelius T. Ryan
------------------------------------------
General Partner
Page 14 of 15 pages
<PAGE>
OBP MANAGEMENT (BERMUDA) LTD.
By: /s/ Cornelius T. Ryan
-----------------------------------------
Title: General Partner
/s/ Cornelius T. Ryan
----------------------------------------------
Cornelius T. Ryan
/s/ Alan G. Walton
----------------------------------------------
Alan G. Walton
/s/ Edmund M. Olivier
----------------------------------------------
Edmund M. Olivier
Page 15 of 15 pages
