IXION BIOTECHNOLOGY INC
8-K, EX-99.10, 2000-07-28
PHARMACEUTICAL PREPARATIONS
Previous: IXION BIOTECHNOLOGY INC, 8-K, EX-99.9, 2000-07-28
Next: ABN AMRO MORTGAGE CORP, 8-K, 2000-07-28





Dear Shareholders:

     We have successfully closed the Q-Med transaction, in which we will receive
slightly less than $7 million to move Ixion  forward to the next level.  See the
press release below:

For Immediate  Release

Swedish Company Buys Majority Interest in Ixion Biotechnology

ALACHUA, FL. July 17, 2000- Qvestor,  LLC, a U.S. subsidiary of Q-Med AB (publ),
a  biotechnology  and  medical  device  company  based in  Uppsala,  Sweden (not
affiliated  in any way with  Q-Med,  Inc.,  a  Nasdaq-listed  US  company),  has
purchased 3,337,500  newly-issued shares of common stock of Ixion Biotechnology,
an Alachua County,  Fla.-based biotech firm, for a total of $6,675,000 and other
consideration.

     Q-Med had already  purchased  562,500 Ixion shares at a cash price of $2.00
per share since  entering  into an agreement  in principal in April 1999.  Under
that  agreement,  it also had an option to acquire  up to 50% of Ixion's  common
stock on a fully-diluted basis. Q-Med's board has decided to exercise its option
by buying  the  additional  shares at the option  price of $2.00 per share.  The
board of Ixion approved the transaction on July 14, and half of the purchase sum
was paid at the closing later the same day. The remainder  will be paid no later
than 12 months after.  Following  the closing,  Qvestor and Q-Med now own 59% of
Ixion's outstanding common stock.

     Weaver H.  Gaines,  Chairman  of Ixion,  said  that the  transaction  would
provide  funds for two years of expanded  operations.  "We have worked well with
Q-Med in the last 15  months,  and we have high  expectations  for our  expanded
relationship,"  Mr.  Gaines  said.  "Q-Med wants us to continue to operate as an
independent  company where they will exercise their influence primarily through
our board."

     Q-Med is a rapidly growing and profitable  biotechnology and medical device
company that develops,  produces and markets  non-animal  hyaluronic  acid based
medical  implants.  All of Q-Med's products are based on the company's  patented
technology  for the  production of non-animal  stabilized  hyaluronic  acid, or
NASHA.  The majority of Q-Med's  revenues are accounted for by Restylane(R)  for
the filling out of lips, facial wrinkles, and facial folds.

     Ixion's stem cell technology  involves using islets generated in vitro from
pancreatic stem cells from adult donors to produce new islets to treat diabetes.
The  technology  would  represent  the ability to culture  relatively  unlimited
numbers of islet cells from a piece of the pancreas of a diabetic individual and
produce  sufficient islets to reinfuse later as a treatment for diabetes.  Ixion
is developing  products based on its Islet  Producing Stem Cell  technology.  So
far,  Ixion has studied the ability to propagate  and  differentiate  islet stem
cells in vitro, which will provide human islets for use in cell  transplantation
therapy  to  treat  type  1  diabetes.  In  further  research,  islets  will  be
encapsulated in a patented hyaluronic gel supplied by Q-Med. Q-Med is working to
develop the hyaluronic acid to encapsulate Ixion's islets or explanted islets in
order to protect them after transplantation.

     "The  combination  of Ixion's  stem-cell  technology and Q-Med's NASHA gels
offers unique research and commercial  opportunities,"  says Q-Med's  President
and CEO, Per Olof Wallstrom.  Mr. Wallstrom joined Ixion's seven member board at
the meeting on July 14, 2000.

     Ixion specializes in discovering,  developing,  manufacturing and marketing
products to treat and prevent  diabetes.  Recently,  Ixion received  broad-based
media attention for its research  showing the feasibility of using stem cells to
produce new pancreatic tissue to treat and possibly cure diabetes.  The company,
which holds  worldwide  exclusive  licenses  to patents and pending  patents for
diabetes treatments,  also holds exclusive licenses to patents for treatments of
oxalate-related  disorders,  such as kidney stones,  Crohn's  Disease and cystic
fibrosis.  For more information about Ixion's current activities,  visit Ixion's
website at  www.ixion-biotech.com  or call 904-418-1428.  More information about
Q-Med is available at www.q-med.com.

     This  news   release   discusses   historical   information   and  includes
forward-looking  statements  that  involve a number of risks and  uncertainties,
such as risks  associated  with  pre-clinical  and clinical  development  in the
biotechnology   industry,   determinations  by  regulatory  and   administrative
governmental authorities,  competitive factors,  technological developments and
costs of developing, producing and selling products.

     Contacts:

          Weaver  H.  Gaines   Lisette  Hilton

          Ixion Biotechnology,   Inc.   (561)392-5649   (voice)
          631-583-5203   (voice)
          [email protected]




© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission