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U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
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<S> <C> <C>
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======================= OMB APPROVAL
FORM 4 OMB Number: 3235-0287
======================= STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Expires: December 31, 2001
Estimated average burden
[ ] CHECK THIS BOX IF NO Filed pursuant to Section 16(a) of the Securities hours per response......0.5
LONGER SUBJECT TO SECTION 16. Exchange Act of 1934, Section 17(a) of the -----------------------------
FORM 4 OR FORM 5 OBLIGATIONS Public Utility Holding Company Act of 1935 or
MAY CONTINUE. SEE INSTRUCTION 1(b) Section 30(f) of the Investment Act of 1940
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<TABLE>
<S> <C> <C>
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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to
Issuer (Check all applicable)
MIZELLE THOMAS VION PHARMACEUTICALS, INC. (VION) Director 10% Owner
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(Last) (First) (Middle) 3. IRS Identification 4. Statement for
Number of Reporting Month/Year X Officer Other
C/O VION PHARMACEUTICALS, INC. Person, if an entity --- ---
4 Science Park (voluntary) NOVEMBER 2000 (give title (specify below)
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(Street) 5. If Amendment,
Date of Original Vice President-Operations and Secretary
NEW HAVEN CT 06511 (Month/Year) ---------------------------------------
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(City) (State) (Zip) 7. Individual or Joint/Group Filing
(Check Applicable Line)
X Form filed by One
--- Reporting Person
Form filed by More than One
Reporting Person
---
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TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
<TABLE>
<CAPTION>
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1. Title of Security (Inst. 3) 2. Transaction Date 3. Transaction Code 4. Securities Acquired (A) or Disposed of (D)
(Mo/Day/Yr) (Inst. 8) (Inst. 3, 4 and 5)
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Code V Amount (A) or (D) Price
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<S> <C> <C> <C> <C> <C> <C>
Common Stock, $.01 par value 11/30/2000 M 6,762 A $4.1875
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<CAPTION>
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5. Amount of 6. Ownership 7. Nature of
Securities Form: Indirect
Beneficially Direct (D) or Beneficial
Owned at Indirect (I) Ownership
End of Month (Instr. 4) (Instr. 4)
(Instr. 3 and 4)
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<S> <C> <C>
27,772 D
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Reminder: Report on a separate line for class of securities beneficially
owned directly or indirectly. (Over)
SEC 1474 (7-96)
(Print or Type Responses)
* If the form is filed by more than one reporting person, see
Instruction 4(b)(v).
Page 1 of 2
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<TABLE>
<CAPTION>
FORM 4 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
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1. Title of Derivative 2. Conversion 3. Transaction 4. Transaction 5. Number of Derivative 6. Date Exercisable and
Security (Instr. 3) or Exercise Date Code (Instr. 8) Securities Acquired Expiration Date
Price of (Mo/Day/Yr) (A) or Disposed of (D) (Mo/Day/Yr)
(Instr. 3,4,5)
Warrants to purchase Derivative ------------------------------------------------------------------------
Common Stock, $0.01 Security
par value per share
("Common Stock") Date Expiration
Code V (A) (D) Exercisable Date
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<S> <C> <C> <C> <C> <C> <C> <C> <C>
Options to purchase $4.1875 11/30/2000 M 6,762 (1) 10/14/2006
Common Stock
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<CAPTION>
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7. Title & Amount of 8. Price of 9. Number of 10. Ownership 11. Nature of
Underlying Securities Derivative Derivative Form of Indirect
(Instr. 3 & 4) Security Securities Derivative Beneficial
------------------------ (Instr. 5) Beneficially Security Ownership
Amount Owned at Direct (D) (Inst. 4)
or End of or
Number Month Indirect (1)
of (Inst. 4) (Inst. 4)
Title Shares
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<S> <C> <C> <C> <C> <C>
Common 6,762 0 D
Stock
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</TABLE>
Explanation of Responses:
(1) Options vested in four equal installments on October 14, 1997, October 14,
1998, October 14, 1999 and October 14, 2000.
/s/ Thomas Mizelle December 7, 2000
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**Thomas Mizelle Date
** Intentional misstatements or omissions of facts constitute Federal Criminal
Violations
See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed.
If space is insufficient, see Instruction 6 for procedure.
Potential persons who are to respond to the collection of information
contained in this form are not required to respond unless the form
displays a currently valid OMB Number.
SEC 1474 (7/96)
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