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U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
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<S> <C> <C>
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======================= OMB APPROVAL
FORM 4 OMB Number: 3235-0287
======================= STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Expires: December 31, 2001
Estimated average burden
[ ] CHECK THIS BOX IF NO Filed pursuant to Section 16(a) of the Securities hours per response......0.5
LONGER SUBJECT TO SECTION 16. Exchange Act of 1934, Section 17(a) of the -----------------------------
FORM 4 OR FORM 5 OBLIGATIONS Public Utility Holding Company Act of 1935 or
MAY CONTINUE. SEE INSTRUCTION 1(b) Section 30(f) of the Investment Act of 1940
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<TABLE>
<S> <C> <C>
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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to
Issuer (Check all applicable)
SZNOL MARIO VION PHARMACEUTICALS, INC. (VION) Director 10% Owner
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(Last) (First) (Middle) 3. IRS Identification 4. Statement for
Number of Reporting Month/Year X Officer Other (specify below)
C/O VION PHARMACEUTICALS, INC. Person, if an entity --- ---
4 Science Park (voluntary) NOVEMBER 2000 (give title
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(Street) 5. If Amendment,
Date of Original Vice President - Clinical Affairs
NEW HAVEN CT 06511 (Month/Year) --------------------------------------
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(City) (State) (Zip) 7. Individual or Joint/Group Filing
(Check Applicable Line)
X Form filed by One Reporting Person
---
Form filed by More than One
--- Reporting Person
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TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
<TABLE>
<CAPTION>
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1. Title of Security (Inst. 3) 2. Transaction Date 3. Transaction Code 4. Securities Acquired (A) or Disposed of (D)
(Mo/Day/Yr) (Inst. 8) (Inst. 3, 4 and 5)
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Code V Amount (A) or (D) Price
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<S> <C> <C> <C> <C> <C> <C>
Common Stock, $.01 par value 11/30/2000 M 3,000 A $5.0630
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<CAPTION>
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5. Amount of 6. Ownership 7. Nature of
Securities Form: Indirect
Beneficially Direct (D) or Beneficial
Owned at Indirect (I) Ownership
End of Month (Instr. 4) (Instr. 4)
(Instr. 3 and 4)
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<S> <C> <C>
3,000 D
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Reminder: Report on a separate line for class of securities beneficially
owned directly or indirectly. (Over)
SEC 1474 (7-96)
(Print or Type Responses)
* If the form is filed by more than one reporting person, see
Instruction 4(b)(v).
Page 1 of 2
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FORM 4 (CONTINUED)
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<CAPTION>
TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
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1. Title of Derivative 2. Conversion 3. Transaction 4. Transaction 5. Number of Derivative
Security (Instr. 3) or Date Code (Instr. 8) Securities Acquired (A)
Exercise (Mo/Day/Yr) or Disposed of (D)
Warrants to purchase Price of (Instr. 3,4,5)
Common Stock, $0.01 ----------------------------------------------------------------
par value per share
("Common Stock") Derivative
Security
Code V (A) (D)
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<S> <C> <C> <C> <C> <C> <C>
Options to purchase $5.0630 11/30/2000 M 3,000
Common Stock
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<CAPTION>
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6. Date Exercisable and 7. Title & Amount of 8. Price of 9. Number of 10. Ownership 11. Nature of
Expiration Date Underlying Derivative Derivative Form of Indirect
(Mo/Day/Yr) Securities Security Securities Derivative Beneficial
(Instr. 3 & 4) (Instr.5) Beneficially Security Ownership
Owned at Direct (D) (Inst. 4)
End of or
Month Indirect (I)
(Inst. 4) (Inst. 4)
----------------------------------------------------
Amount
or
Number
Date Expiration of
Exercisable Date Title Shares
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<S> <C> <C> <C> <C> <C> <C> <C>
11/09/2000 11/09/2009 Common 3,000 7,606 D
Stock
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</TABLE>
Explanation of Responses:
/s/ Mario Sznol December 7, 2000
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**Mario Sznol Date
** Intentional misstatements or omissions of facts constitute Federal Criminal
Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be
manually signed. If space is insufficient, see Instruction
6 for procedure. Potential persons who are to respond to the collection
of information contained in this form are not required to respond unless
the form displays a currently valid OMB Number.
SEC 1474 (7/96)
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