DISCOVERY LABORATORIES INC /DE/
10QSB, 2000-05-15
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549



                                   FORM 10-QSB


|X|      QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934

                  For the quarterly period ended March 31, 2000

                                       or

|_|      TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934

           For the transition period from _____________ to ___________
                        Commission file number 000-26422


                          DISCOVERY LABORATORIES, INC.
        (Exact name of small business issuer as specified in its charter)

<TABLE>
<S> <C>                                                              <C>

                               Delaware                                           94-3171943
    (State or other jurisdiction of incorporation or organization)   (I.R.S. Employer Identification No.)

                   350 South Main Street, Suite 307
                       Doylestown, Pennsylvania                                     18901
               (Address of principal executive offices)                           (Zip Code)
</TABLE>

       Registrants' telephone number, including area code: (215) 340-4699
      Securities registered under Section 12(b) of the Exchange Act: None
        Securities registered under Section 12(g) of the Exchange Act:
                     Common Stock, par value $.001 per share
Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  Registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days. |X| Yes |_| No

As of May 8, 2000, 20,781,499 shares of Common Stock, par value $.001 per share,
were outstanding.

Documents incorporated by reference:  None.

Transitional Small Business Disclosure Format: |_| Yes   |X| No

953293.1                                                                  Page 1
<PAGE>


                          DISCOVERY LABORATORIES, INC.

                                Table of Contents

<TABLE>
<CAPTION>
                                                                           Page

PART I - FINANCIAL INFORMATION

 <S>      <C>                                                                          <C>

 Item 1.  Financial Statements (unaudited)
            CONSOLIDATED BALANCE SHEETS --
             As of March 31, 2000 (unaudited) and December 31, 1999                    Page 3

            CONSOLIDATED STATEMENTS OF OPERATIONS  (unaudited) --
             For the Three Months Ended March 31, 2000 and March 31, 1999
             and
             for the Period from May 18, 1993 (Inception) through March 31,2000        Page 4

            CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS EQUITY (unaudited)--
             For the Three Months Ended March 31, 2000                                 Page 5

            CONSOLIDATED  STATEMENTS OF CASH FLOWS  (unaudited)--
              For the Three Months Ended March 31, 2000 and March 31, 1999
              and
              for the Period from May 18, 1993 (Inception) through March 31, 2000      Page 6

            Notes to Financial Statements                                              Page 7

 Item 2.  Management's Discussion and Analysis of Financial Condition
          and Results of Operations                                                    Page 7
</TABLE>


PART II - OTHER INFORMATION
<TABLE>
 <S>      <C>                                                                          <C>
 Item 1.  Legal Proceedings.                                                           Page 10
 Item 2.  Change in Securities.                                                        Page 10
 Item 3.  Defaults Upon Senior Securities.                                             Page 10
 Item 4.  Submission of Matters to a Vote of Security Holders.                         Page 10
 Item 5.  Other Information.                                                           Page 10
 Item 6.  Exhibits and Reports on Form 8-K.                                            Page 10

 Signatures                                                                            Page 11
</TABLE>
953293.1                                                                  Page 2

<PAGE>

DISCOVERY LABORATORIES, INC. AND SUBSIDIARY
(a development stage company)

Consolidated Balance Sheets
<TABLE>
<CAPTION>

                                                                                            March 31,         December 31,
                                                                                              2000                1999
                                                                                              ----                ----
                                                                                          (Unaudited)
<S>                                                                                    <C>                  <C>
ASSETS

Current assets:
   Cash and cash equivalents                                                           $      23,591,000    $      3,547,000
   Inventory                                                                                     575,000             575,000
   Prepaid expenses and other current assets                                                     122,000              66,000
                                                                                       -----------------    ----------------

        Total current assets                                                                  24,288,000           4,188,000

Property and equipment, net of deprecation                                                       447,000             426,000
Security deposits                                                                                 18,000              18,000
                                                                                       -----------------    ----------------

                                                                                       $      24,753,000    $      4,632,000
                                                                                       =================    ================

LIABILITIES AND STOCKHOLDERS' EQUITY

Current liabilities:
   Accounts payable and accrued expenses                                               $         694,000    $        425,000
   Deferred revenue                                                                            1,036,000           1,036,000
   Capitalized lease - current                                                                    15,000              15,000
                                                                                       -----------------    ----------------

      Total current liabilities                                                                1,745,000           1,476,000
                                                                                       -----------------    ----------------

Capitalized lease - noncurrent                                                                    44,000              48,000
                                                                                       -----------------    ----------------

Commitments

Stockholders' Equity:
   Preferred stock, $.001 par value; 5,000,000 shares authorized:
      Series B convertible; None and 1,530,756 shares issued and outstanding at                                        2,000
      March 31, 2000 and December 31, 1999, respectively
      Series C redeemable convertible; None and 2,039 shares issued and outstanding                                2,481,000
      at March 31, 2000 and December 31, 1999, respectively.
   Common stock, $.001 par value; 35,000,000 authorized; 20,721,135 and 9,689,240                 21,000              10,000
      shares issued and outstanding at March 31, 2000 and December 31, 1999
      respectively
   Treasury stock (at cost; 33,743 and 2,000 shares of common stock at March 31,                (250,000)             (5,000)
      2000 and December 31, 1999, respectively)
   Additional paid-in capital                                                                 57,828,000          33,749,000
   Unearned portion of compensatory stock options                                                (37,000)            (37,000)
   Deficit accumulated during the development stage                                          (34,598,000)        (33,092,000)

        Total stockholders' equity                                                            22,964,000           3,108,000
                                                                                       -----------------    ----------------

                                                                                       $      24,753,000    $      4,632,000
                                                                                       =================    ================
</TABLE>

See notes to financial statements                                        Page 3
953293.1
<PAGE>

DISCOVERY LABORATORIES, INC. AND SUBSIDIARY
(a development stage company)

Consolidated Statements of Operations
(Unaudited)

<TABLE>
<CAPTION>

                                                                               May 18, 1993
                                                Three Months Ended             (Inception)
                                                     March 31,                   Through
                                         ---------------------------------       March 31,
                                               2000              1999              2000
                                         --------------    ---------------    --------------

<S>                                      <C>               <C>               <C>
Interest                                 $       22,000    $        37,000   $     1,490,000
License Fees                                                                          68,000
Research Grants                                  19,000                              156,000
                                         --------------    ---------------   ---------------
                                                 41,000             37,000         1,714,000
                                         --------------    ---------------   ---------------

Expenses:
   Write-off of acquired in-process
       research and development and
       supplies                                                                   13,508,000
   Research and development                     774,000          1,419,000        13,643,000
   General and administrative                   735,000            636,000         8,490,000
   Interest                                       2,000                               15,000
                                         --------------    ---------------   ---------------

        Total expenses                        1,511,000          2,055,000        35,656,000
                                         --------------    ---------------   ---------------

                                             (1,470,000)        (2,018,000)      (33,942,000)

Minority interest in net loss of                                                      26,000
subsidiary                               --------------    ---------------   ---------------


Net loss                                     (1,470,000)        (2,018,000)      (33,916,000)

Other comprehensive income:
   Unrealized gain on marketable
       securities available for sale                                (3,000)
                                         --------------    ----------------  ----------------

Total comprehensive loss                 $   (1,470,000)   $    (2,021,000)  $   (33,916,000)
                                         ===============   ================  ================

Net loss per share - basic and diluted       $(0.12)           $(0.36)
                                             ======            ======


Weighted average number of common
shares outstanding                          12,668,000        5,613,000
                                            ==========        =========
</TABLE>

See notes to financial statements                                        Page 4
953293.1
<PAGE>
DISCOVERY LABORATORIES, INC. AND SUBSIDIARY
(a development stage company)

Consolidated Statements of Changes in Stockholders' Equity
December 31, 1999 through March 31, 2000

<TABLE>
<CAPTION>


                                                                                          Preferred Stock
                                  Common Stock          Treasury Stock           Series B             Series C
                              -------------------------------------------------------------------------------------
                               Shares      Amount     Shares     Amount      Shares     Amount   Shares     Amount

<S>                           <C>          <C>       <C>        <C>         <C>         <C>       <C>     <C>
Balance - 12/31/99            9,689,240    $ 10,000   (2,000)   $  (5,000)  1,530,756   $ 2,000   2,039   $ 2,481,000

Exercise of Stock Options       445,259           -  (31,743)    (245,300)

Common placement
warrant conversions              14,130           -

Preferred placement
warrant conversions               8,511           -

Exercise of Class C & D
Warrants                      2,480,009       3,000

Series B preferred stock
conversions                   4,765,631       5,000                        (1,530,756)   (2,000)

Dividend Payable on Series
C preferred stock                                                                                              36,000

Series C prefered stock
conversions                     398,186                                                          (2,039)   (2,517,000)

Common stock issued in
payment for services              7,323           -

Issuance of private
placement units               2,902,846       3,000

Net Loss
- ------------------------------------------------------------------------------------------------------------------------
Balance - 03/31/00           20,721,135    $ 21,000   (33,743)   $(250,300)          -         -       -             -
========================================================================================================================
</TABLE>

<TABLE>
<CAPTION>
                                                                        Deficit
                                                                      Accumulated
                               Additional      Unearned Portion of      during
                                Paid-In        Compensatory Stock     Development
                                Capital             Options              Stage             Total

<S>                          <C>               <C>                    <C>              <C>
Balance - 12/31/99           $ 33,749,000      $ (37,000)             $ (33,092,000)   $  3,108,000

Exercise of Stock Options         440,000                                              $    195,000

Common placement
warrant conversions                     -                                              $          -

Preferred placement
warrant conversions                     -                                              $          -

Exercise of Class C & D
Warrants                        3,668,000                                              $  3,671,000

Series B preferred stock
conversions                        (3,000)                                             $          -

Dividend Payable on Series
C preferred stock                                                           (36,000)   $          -

Series C prefered stock
conversions                     2,517,000                                              $          -

Common stock issued in
payment for services               36,000                                              $     36,000

Issuance of private
placement units                17,421,000                                              $ 17,424,000

Net Loss                                                                 (1,470,000)   $ (1,470,000)
- ----------------------------------------------------------------------------------------------------
Balance - 03/31/00           $ 57,828,000      $ (37,000)             $ (34,598,000)   $ 22,964,000
====================================================================================================
</TABLE>

See notes to financial statements                                         Page 5
953293.1
<PAGE>

DISCOVERY LABORATORIES, INC. AND SUBSIDIARY
(a development stage company)

Consolidated Statements of Cash Flows
(Unaudited)

<TABLE>
<CAPTION>

                                                                                Three Months Ended             May 18, 1993
                                                                                     March 31,                 (Inception)
                                                                                                                 Through
                                                                                                                March 31,
                                                                                2000            999                2000
                                                                           -------------  ---------------   -----------------
<S>                                                                        <C>            <C>               <C>
Cash flows from operating activities:
   Net loss                                                                $ (1,470,000)  $   (2,018,000)   $    (33,916,000)
   Adjustments to reconcile net loss to net cash used in operating
      activities
        Write-off of acquired in-process research and development and
           supplies                                                                                               13,508,000
        Write-off of licenses                                                                                        683,000
        Depreciation and amortization                                            24,000           19,000             240,000
        Compensatory stock options                                                                 8,000             142,000
        Expenses paid using treasury stock and common stock                      36,000                              114,000
        Changes in:
           Prepaid expenses and other current assets                            (56,000)         126,000             (91,000)
           Accounts payable and accrued expenses                                269,000          279,000             561,000
           Deferred revenue                                                                                        1,036,000
           Other assets                                                                                              (18,000)
        Expenses paid on behalf of company                                                                            18,000
        Employee stock compensation                                                                                   42,000
        Reduction of research and development supplies                                                              (161,000)
                                                                         --------------   --------------    ----------------
           Net cash used in operating activities                             (1,197,000)      (1,586,000)        (17,842,000)
                                                                         --------------   --------------    ----------------

Cash flows from investing activities:
   Purchase of furniture and equipment                                          (45,000)         (14,000)           (591,000)
    Proceeds from disposal of furniture and equipment                                                                 25,000
   Acquisition of licenses                                                                                          (711,000)
   Purchase of marketable securities                                                                             (21,745,000)
   Proceeds from sale or maturity of investments                                               1,078,000          22,150,000
   Net cash payments on merger                                                                                    (1,670,000)
                                                                         --------------   --------------    -----------------
           Net cash provided by (used in) investing activities                  (45,000)       1,064,000          (2,542,000)
                                                                         ---------------  --------------    ----------------

Cash flows from financing activities:
   Proceeds on private placements of units, net of expenses                  17,424,000                           40,146,000
   Purchase of treasury stock                                                                     (5,000)            (95,000)
   Principal payments under capital lease obligation                             (4,000)                             (14,000)
   Collections on stock subscriptions and proceeds on conversion of
       stock options and warrants                                             3,866,000            4,000           3,938,000
                                                                         --------------   --------------    ----------------
           Net cash (used in) provided by financing activities               21,286,000           (1,000)         43,975,000
                                                                         --------------   ---------------   ----------------

Net (decrease) increase in cash and cash equivalents                         20,044,000         (523,000)         23,591,000
Cash and cash equivalents - beginning of period                               3,547,000        1,474,000
                                                                         --------------   --------------    ----------------

Cash and cash equivalents - end of period                                $   23,591,000   $      951,000    $     23,591,000
                                                                         ==============   ==============    ================
Supplementary disclosure of cash flows information:
    Interest Paid:                                                       $        2,000                     $         15,000
Noncash transactions:
   Accrued dividends on preferred stock                                  $       36,000   $       51,000    $        682,000
   Common stock and treasury stock issued in payment of services                 36,000           69,000             109,000
   Preferred Stock issued for inventory                                                                              575,000
   Treasury stock received on exercise of options                               245,000                              245,000

   Equipment acquired through capitalized lease                                                                       73,000

   Series C preferred stock dividends paid using common stock                                                        204,000
</TABLE>

See notes to finanical statements                                         Page 6
593293.1
<PAGE>

NOTE 1 - THE COMPANY AND BASIS OF PRESENTATION

The Company

Discovery  Laboratories,  Inc. (the "Company") was formed to license and develop
pharmaceutical  products to treat a variety of human diseases.  The accompanying
financial  statements  include the  accounts of the Company and its wholly owned
subsidiary, Acute Therapeutics,  Inc. All intercompany balances and transactions
have been eliminated.

The accompanying  unaudited,  consolidated,  condensed financial statements have
been prepared in accordance with generally  accepted  accounting  principles for
interim  financial  information  in  accordance  with the  instructions  to Form
10-QSB.  Accordingly,  they do not include all of the  information and footnotes
required by generally  accepted  accounting  principles  for complete  financial
statements.  In the  opinion  of  management,  all  adjustments  (consisting  of
normally  recurring  accruals)   considered  for  fair  presentation  have  been
included.  Operating results for the three-month period ended March 31, 2000 are
not  necessarily  indicative  of the results  that may be expected  for the year
ended  December 31, 2000.  For further  information,  refer to the  consolidated
financial statements and footnotes thereto included in the Company's 1999 Annual
Report on form 10-KSB.

The  Company's  activities  since  incorporation  have  primarily  consisted  of
conducting research and development,  performing business and financial planning
and  raising  capital.  Accordingly,  the  Company  is  considered  to be in the
development stage, and expects to incur increasing losses and require additional
financial resources to achieve commercialization of its products.

The Company also depends on third  parties to conduct  research on the Company's
behalf  through  various  research  agreements.  All  of the  Company's  current
products under  development are subject to license  agreements that will require
the payment of future royalties.

Net Loss Per Share

Net loss per share is computed  based on the weighted  average  number of common
shares  outstanding  for the periods and common shares issuable for little or no
cash  consideration.  Common  shares  issuable  upon the exercise of options and
warrants and the  conversion of  convertible  securities are not included in the
calculation of the net loss per share as their effect would be antidilutive.


ITEM 2. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
OF OPERATIONS

Plan of Operations

Since its inception,  the Company has  concentrated its efforts and resources on
the   development  and   commercialization   of   pharmaceutical   products  and
technologies.  The Company has been  unprofitable  since its  inception  and has
incurred a cumulative  net loss of  approximately  $33.9 million as of March 31,
2000. The Company expects to incur  significantly  increasing  operating  losses
over the next several years,  primarily due to the expansion of its research and
development programs,  including clinical trials for some or all of its existing
products  and  technologies  and other  products  and  technologies  that it may
acquire or develop. The Company's ability to achieve profitability depends upon,
among  other  things,  its  ability to discover  and  develop  products,  obtain
regulatory  approval for its proposed  products,  and enter into  agreements for
product development, manufacturing and commercialization.  None of the Company's
products currently generates revenues and the Company does not expect to achieve
product revenues for the foreseeable future. Moreover, there can be no assurance
that the Company will ever achieve significant revenues or profitable operations
from the sale of any of its products or technologies.

The Company is a  development  stage  pharmaceutical  company that is focused on
developing  compounds  intended  for  neonatal  use in  critical  care  hospital
settings.   The  Company  is  also   developing  its  lead  product   candidate,
Surfaxin(R),  for the treatment of various critical care respiratory conditions.
The  Company  anticipates  that  during  the  next 12  months  it  will  conduct
substantial research and development of its compounds.

The Company is currently  engaged in the  development and  commercialization  of
drugs for critical care that are intended to be used in a hospital setting.  The
Company  anticipates that during the next 12 months it will conduct  substantial
research and  development  of its products  under  development  and that it will
focus primarily on the conduct of clinical  trials for Surfaxin(R)  indications.
The Company  expects to expand its  research  and  development  activities  as a
result of its receipt of  approximately  $17.4  million of net proceeds from its
offering completed in

953293.1                                                                  Page 7

<PAGE>

March 2000.  The Company  anticipates  the near term  acquisition  of  equipment
necessary to manufacture Surfaxin(R). The Company also anticipates the hiring of
further personnel to augment the clinical development of Surfaxin(R).

SURFAXIN(R) (lucinactant)

Meconium Aspiration Syndrome (MAS)

The Company recently initiated a pivotal Phase 3 trial in MAS. The trial intends
to enroll 200 MAS patients.  The Company announced results of a Phase 2 clinical
trial in MAS in full-term  newborns in February  1999.  The  22-patient  Phase 2
trial showed an improvement in oxygenation parameters and a three-day savings on
mechanical  ventilation.  An Orphan  Products  Development  Grant awarded to the
Company  by the FDA  Office  of  Orphan  Products  Development  is  expected  to
contribute  significantly  towards reducing the costs of this Phase 3 trial. The
Company has received Fast Track  designation  for  Surfaxin(R)  from the FDA for
MAS.

Respiratory Distress Syndrome (RDS) in premature infants

The  Company is  currently  planning  to  commence  a Phase 3 clinical  trial of
Surfaxin(R)  for the  treatment of RDS in premature  infants  during 2000.  Such
trial,  and any other clinical  trials of the Company's  products in development
that have not yet  commenced,  will require the  approvals by the United  States
Food and Drug Administration (the "FDA") and/or world health authorities.  There
can be no assurance as to the receipt or the timing of such approvals.

Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)

A pivotal  Phase 2/3 clinical  trial of Surfaxin for  the treatment of ALI/ARDS
was  commenced  in July 1998.  This trial was stopped on January 27, 2000 due to
the Company's  cash  position and so that a new Phase 2 ARDS/ALI  trial could be
commenced using a new, less viscous  formulation of  Surfaxin(R).  A new Phase 2
trial is  currently  being  planned,  which  the  Company  expects  to  commence
following  submission  of a protocol  and  subsequent  agreement by the FDA. The
Company has received Fast Track  designation  for  Surfaxin(R)  from the FDA for
ARDS.

SUPERVENT(TM) (tyloxapol)

Cystic Fibrosis (CF)

The Company began a Phase 2A clinical trial of  SuperVent(TM)  for the treatment
of  CF  on  August  4,  1999.   Preliminary  analysis  of  the  data  show  that
SuperVent(TM)  decreased  the  amount of  Interleukin  8 (IL-8) in the sputum of
treated patients  compared to controls.  IL-8 is an important body chemical that
causes the migration of inflammatory cells to the site of release.  The Phase 2A
clinical trial involved 8 patients.  An additional  Phase 2 trial will likely be
required  prior to  commencement  of a Phase 3 trial.  Previously,  the  Company
completed a Phase 1 trial in 20 normal healthy  volunteers and determined a dose
(1.25%  tyloxapol  concentration)  that  did  not  produce  significant  adverse
effects.

Chronic Bronchitis (CB)

The  Company  plans  to  investigate  the  potential  clinical   application  of
SuperVent(TM) in CB following its successful Phase 2A trial in CF. A pilot study
will be reviewed during 2000.

DSC-103 (Vitamin D analog)

Postmenopausal Osteoporosis

On December 5, 1997 a Phase 1 clinical study of DSC-103 as a once-daily,  orally
administered drug for the treatment of postmenopausal osteoporosis in the United
States was  initiated.  Part B of such trial was  commenced on April 2, 1998 and
was  successfully  completed  on June 29, 1998.  The Company has had discussions
with the licensor of D5C-103 regarding the possibility of terminating its
license.

Results of Operations

The Company's expenses decreased from $2,055,000 in the first quarter of 1999 to
$1,511,000 in the first quarter of 2000.  The decrease was primarily a slow-down
in research and development  due to the Company's cash position.  As a result of
the receipt of proceeds from the private placement completed in March, 2000, the
Company  expects to  significantly  increase its research  and  development  and
clinical trial efforts. As a result of the decreases in expenses,  the Company's
total  comprehensive  net loss decreased from $2,021,000 in the first quarter of
1999 to  $1,470,000  in the  first  quarter  of 2000.  In  addition,  due to the
reduction in the total

593293.1                                                                  Page 8
<PAGE>

comprehensive  net loss and the increase in the weighted  average  common shares
outstanding  during the first quarter of 2000,  the Company's net loss per share
decreased from $0.36 in 1999 to $0.12 in 2000.

Liquidity

At March 31, 2000, the Company had working  capital of $22.5  million.  In March
2000, the Company  completed a private  placement  pursuant to which it received
net  proceeds  of  approximately  $17.4  million.  The  Company  believes it has
sufficient  resources to meet its planned  research and  development  activities
through the fourth quarter 2001.

The Company  will be required to raise  additional  capital in order to meet its
business objectives, and there can be no assurance that it will be successful in
doing so or, in general,  that the Company  will be able to achieve its business
objectives.

The Company's  working capital  requirements  will depend upon numerous factors,
including,   without   limitation,   progress  of  the  Company's  research  and
development  programs,  preclinical  and  clinical  testing,  timing and cost of
obtaining regulatory approvals,  levels of resources that the Company devotes to
the  development  of  manufacturing  and marketing  capabilities,  technological
advances,  status of  competitors  and the ability of the  Company to  establish
collaborative arrangements with other organizations.

Safe Harbor Statement Under the Private Securities Litigation Act of 1996

Certain  statements  set forth in this report,  including,  without  limitation,
statements  concerning  the Company's  research and  development  programs,  the
possibility of submitting  regulatory  filings for the Company's  products under
development,  the  seeking of  collaboration  arrangements  with  pharmaceutical
companies or others to develop,  manufacture and market  products,  the research
and development of particular  compounds and technologies and the period of time
for which the Company's  existing  resources will enable the Company to fund its
operations,   are  forward-looking   statements.  All  such  statements  involve
significant risks and  uncertainties.  Actual results may differ materially from
those  contemplated in the forward  looking  statements as a result of risks and
uncertainties, including but not limited to the following: the Company's ability
to obtain  substantial  additional  funds;  the  uncertainties  inherent  in the
process of developing  products of the kind being developed by the Company;  the
Company's   ability  to  establish   additional   collaborative   and  licensing
arrangements and the degree of success of the Company's  collaboration partners;
the Company's  ability to obtain and maintain all necessary patents or licenses;
the  Company's  ability  to  demonstrate  the  safety  and  efficacy  of product
candidates and to receive required regulatory  approvals;  the Company's ability
to meet  obligations and required  milestones under its license  agreement;  the
Company's ability to compete  successfully  against other products and to market
products in a profitable  manner; and other risks and uncertainties set forth in
the Company's filings with the Securities and Exchange Commission.

593293.1                                                                  Page 9

<PAGE>

PART II - OTHER INFORMATION

ITEM 1.  LEGAL PROCEEDINGS

None.

ITEM 2.  CHANGE IN SECURITIES.
On March  23,  2000,  the  Company  received  approximately  $17,400,000  in net
proceeds from the sale of 37.74 units in a private placement. Each unit consists
of 76,923  shares of common stock and Class E warrants to purchase an additional
15,385  shares  of common  stock at $7.38 per  share.  In  connection  with this
private placement,  the placement agent,  Paramount Capital, Inc.  ("Paramount")
received  fees of  $1,321,000  and the  Company  agreed  to issue  to  Paramount
warrants to purchase 348,341 shares of common stock at $8.11 per share.

During the Quarter  ended March 31, 2000,  the company  received  $3,671,689  in
proceeds  from the  exercise of 2,024,792  Class D warrants and 455,217  Class C
warrants.

For each of the issuances  described above, the securities received by investors
were deemed to be exempt from registration  under the Act in reliance on Section
4(2) thereof because such issuance did not involve a public offering.  Investors
in each  financing  represented  their  intention to acquire the  securities for
investment  only  and not  with a view to or for  sale in  connection  with  any
distribution  thereof and  appropriate  legends were  affixed to the  securities
certificates  issued in such  transactions.  The investors in each financing had
adequate  access to  information  about the Company.  Moreover,  such  investors
represented to the Company, and the Company believed, that they were experienced
in financial matters.

On March 3, 2000,  Johnson & Johnson,  Inc.  elected to convert  their shares of
Series C Preferred stock into 398,186 shares of common stock. Subsequent to this
conversion,  the  Company no longer has any shares of Series C  Preferred  stock
outstanding.

On March 14, 2000,  the Company  forced the  conversion  of all its  outstanding
Series B Preferred Stock  (827,750) into common.  Pursuant to Section Fourth (B)
(5) of the Restated  Certificate of  Incorporation  of the Company,  the Company
exercised its right to cause the conversion.  Subsequent to this conversion, the
Company no longer has any classes of Preferred  stock  outstanding  nor any long
term debt.

ITEM 3.  DEFAULTS UPON SENIOR SECURITIES.

None.

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

None

ITEM 5. OTHER  INFORMATION.

The Company has entered  into an agreement  to purchase an  approximately  4,000
square  foot  building  adjacent  to  its  current  headquarters  in  Doylestown
Pennsylvania for $515,000. The Company intendS to close on this purchase on June
30, 2000.

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K.

         (a) Exhibits:

                1.     Form of Class E Warrant

                27.1   Financial Data Schedule.

         (b) Reports on Form 8-K:
                1.       Form 8-K filed with the Commission on February 8, 2000.
                2.       Form 8-K filed with the Commission on March 7, 2000.
                3.       Form 8-K filed with the Commission on March 20, 2000.
                4.       Form 8-K filed with the Commission on March 29, 2000.

593293.1                                                                 Page 10
<PAGE>

SIGNATURES

In accordance  with the  requirements  of the Exchange Act, the  Registrant  has
caused this report to be signed on its behalf by the undersigned, thereunto duly
authorized.

                                 Discovery Laboratories, Inc.
                                         (Registrant)


Date:   May 15, 2000             /s/ Robert J. Capetola
                                 ---------------------------------
                                 Robert J. Capetola, Ph.D.
                                 President/Chief Executive Officer


Date:   May 15, 2000             /s/ Evan Myrianthopoulos
                                 ---------------------------------
                                 Evan Myrianthopoulos
                                 Vice President, Finance
                                 (Principal Financial Officer)


Date:   May 15, 2000             /s/ Cynthia Davis
                                 ---------------------------------
                                 Cynthia Davis
                                 Controller
                                 (Principal Accounting Officer)

953293.1                                                                 Page 11




THE WARRANTS  REPRESENTED  BY  THIS  CERTIFICATE  AND  THE  SECURITIES  ISSUABLE
UPON EXERCISE  THEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933
OR THE SECURITIES  LAWS OF ANY STATE.  NEITHER SUCH WARRANTS NOR SUCH SECURITIES
MAY BE  SOLD,  PLEDGED,  HYPOTHECATED  OR  OTHERWISE  TRANSFERRED  WITHOUT  SUCH
REGISTRATION,  EXCEPT UPON  DELIVERY  TO THE COMPANY OF SUCH  EVIDENCE AS MAY BE
SATISFACTORY  TO COUNSEL FOR THE  COMPANY TO THE EFFECT  THAT ANY SUCH  TRANSFER
SHALL NOT BE IN  VIOLATION OF THE  SECURITIES  ACT OF 1933 OR  APPLICABLE  STATE
SECURITIES LAWS OR ANY RULE OR REGULATION PROMULGATED THEREUNDER.


                          DISCOVERY LABORATORIES, INC.
                          ----------------------------

                        Class E Warrant for the Purchase
                            of Shares of Common Stock


                  FOR VALUE RECEIVED,  DISCOVERY LABORATORIES,  INC., a Delaware
corporation (the "Company"),  hereby certifies that ____________ (the "Holder"),
its designee or its permitted  assigns is entitled to purchase from the Company,
at any time or from time to time  commencing on March 21, 2000 and prior to 5:00
P.M.,  New York City  time,  on March 21,  2005 up to  ________  fully  paid and
non-assessable  shares of common stock (subject to adjustment),  $.001 par value
per share,  of the  Company  for $7.375  per share  (the  "Purchase  Agreement")
(subject  to  adjustment  as provided  herein) an  aggregate  purchase  price of
$__________.  (Hereinafter, (i) said common stock, $.001 par value per share, of
the Company, is referred to as the "Common Stock," (ii) the shares of the Common
Stock purchasable  hereunder or under any other Warrant (as hereinafter defined)
are referred to as the "Warrant  Shares,"  (iii) the  aggregate  purchase  price
payable  for the  Warrant  Shares  purchasable  hereunder  is referred to as the
"Aggregate Warrant Price," (iv) the price payable for each of the Warrant Shares
is referred to as the "Per Share Warrant  Price," (v) this Warrant,  all similar
Warrants issued on the date hereof and all warrants hereafter issued in exchange
or substitution for this Warrant or such similar Warrants are referred to as the
"Warrants,"  and (vi) the holder of this  Warrant is referred to as the "Holder"
and the holder of this  Warrant and all other  Warrants  and Warrant  Shares are
referred to as the  "Holders"  and  Holders of more than 50% of the  outstanding
Warrants and Warrant  Shares are referred to as the "Majority of the  Holders").
The Aggregate Warrant Price is not subject to adjustment.

                  By  acceptance  of this  Warrant,  the Holder agrees to comply
with all applicable  provisions of the Purchase  Agreement to the same extent as
if it were a party thereto.

                  1.  Exercise of Warrant.   a. This Warrant may be exercised in
whole at any time,  or in part from time to time,  commencing  on March 21, 2000
and prior to 5:00 P.M., Eastern Standard Time, on March  21, 2005 by the  Holder
by the surrender of this Warrant (with the

953108.1  5/12/2000  10:52a

<PAGE>



subscription  form at the end hereof duly  executed) at the address set forth in
Section 9(a)  hereof,  together  with proper  payment of the  Aggregate  Warrant
Price, or the  proportionate  part thereof if this Warrant is exercised in part,
with payment for the Warrant  Shares made by  certified  or official  bank check
payable to the order of the Company; or

                  b. If this Warrant is exercised in part,  this Warrant must be
exercised  for a number of whole  shares of the  Common  Stock and the Holder is
entitled to receive a new Warrant covering the Warrant Shares that have not been
exercised and setting  forth the  proportionate  part of the  Aggregate  Warrant
Price applicable to such Warrant Shares.

                  c. Upon surrender of this Warrant,  the Company will (i) issue
a certificate or  certificates  in the name of the Holder for the largest number
of whole shares of the Common  Stock to which the Holder shall be entitled  and,
if this Warrant is exercised in whole,  in lieu of any  fractional  share of the
Common Stock to which the Holder shall be entitled, pay to the Holder cash in an
amount  equal to the fair value of such  fractional  share  (determined  in such
reasonable manner as the Board of Directors of the Company shall determine), and
(ii) deliver the other securities and properties receivable upon the exercise of
this Warrant,  or the proportionate part thereof if this Warrant is exercised in
part, pursuant to the provisions of this Warrant.

                  2. Reservation of Warrant Shares;  Listing. The Company agrees
that,  prior to the  expiration of this Warrant,  the Company shall at all times
(i) have  authorized  and in  reserve,  and shall  keep  available,  solely  for
issuance  and  delivery  upon the  exercise of this  Warrant,  the shares of the
Common Stock and other  securities  and properties as from time to time shall be
receivable upon the exercise of this Warrant, free and clear of all restrictions
on sale or transfer, other than under Federal or state securities laws, and free
and clear of all preemptive  rights and rights of first refusal and (ii) use its
best  efforts to keep the Warrant  Shares  authorized  for listing on the Nasdaq
National Market, the Nasdaq SmallCap Market or any national  securities exchange
on which the Company's Common Stock is traded.

                  3. Protection  Against  Dilution.   a. If, at any time or from
time to time  after  the  date of this  Warrant,  the  Company  shall  issue  or
distribute to any holder of shares of Common Stock evidence of its indebtedness,
any other  securities  of the  Company  or any cash,  property  or other  assets
(excluding  a  subdivision,  combination  or  reclassification,  or  dividend or
distribution payable in shares of Common Stock, referred to in Section 3(b), and
also  excluding  cash  dividends or cash  distributions  paid out of net profits
legally  available  therefor in the full amount  thereof (any such  non-excluded
event being herein  called a "Special  Dividend")),  the Per Share Warrant Price
shall be adjusted by multiplying the Per Share Warrant Price then in effect by a
fraction,  the  numerator  of which shall be the then  Current  Market  Price in
effect on the record date of such issuance or distribution  less the fair market
value (as  determined in good faith by the Company's  Board of Directors) of the
evidence of indebtedness,  cash,  securities or property, or other assets issued
or distributed in such Special Dividend  applicable to one share of Common Stock
and the denominator of which shall be the then Current Market Price in effect on
the record date of such

953108.1  5/12/2000  10:52a             -2-

<PAGE>



issuance or  distribution.  An adjustment  made pursuant to this Subsection 3(a)
shall  become  effective  immediately  after the record date of any such Special
Dividend.

                  b. In case the Company  shall  hereafter (i) pay a dividend or
make a  distribution  to any  holder  of its  capital  stock in shares of Common
Stock,  (ii)  subdivide  its  outstanding  shares of Common Stock into a greater
number of shares,  (iii) combine its  outstanding  shares of Common Stock into a
smaller number of shares or (iv) issue by  reclassification  of its Common Stock
any shares of capital stock of the Company, the Per Share Warrant Price shall be
adjusted  to be  equal  to a  fraction,  the  numerator  of  which  shall be the
Aggregate  Warrant  Price and the  denominator  of which  shall be the number of
shares of Common  Stock or other  capital  stock of the Company  that the Holder
would  have owned  immediately  following  such  action  had such  Warrant  been
exercised  immediately  prior  thereto.  An  adjustment  made  pursuant  to this
Subsection 3(b) shall become effective  immediately after the record date in the
case of a dividend or distribution, and shall become effective immediately after
the   effective   date  in  the   case   of  a   subdivision,   combination   or
reclassification.

                  c. Except as provided in  Subsections  3(a) and 3(b),  in case
the Company  shall  hereafter  issue or sell any Common  Stock,  any  securities
convertible  into Common Stock,  any rights,  options or warrants to purchase or
otherwise  receive an issuance  of Common  Stock or any  securities  convertible
into, or exercisable or exchangeable for, Common Stock, in each case for a price
per share or entitling the holders  thereof to purchase  Common Stock at a price
per share  (determined  by dividing (i) the total  amount,  if any,  received or
receivable  by the  Company in  consideration  of the  issuance  or sale of such
securities  plus the total  consideration,  if any,  payable to the Company upon
exercise  thereof (the "Total  Consideration")  by (ii) the number of additional
shares  of  Common  Stock  issued,  sold  or  issuable  upon  exercise  of  such
securities) that is less than the then (1) Current Market Price in effect on the
date of such  issuance  or sale and (2) the  Redemption  Price  (as  defined  in
Section 7 below),  then the Per Share  Warrant Price shall be adjusted as of the
date of such issuance or sale by multiplying the Per Share Warrant Price then in
effect by a  fraction,  the  numerator  of which shall be (x) the sum of (A) the
number of shares of Common Stock outstanding on the record date of such issuance
or sale plus (B) the Total Consideration divided by the Current Market Price and
the  denominator  of which  shall be (y) the  number of  shares of Common  Stock
outstanding  on the record date of such issuance or sale plus the maximum number
of additional  shares of Common Stock issued,  sold or issuable upon exercise or
conversion of such securities.

                  d. No  adjustment  in the Per  Share  Warrant  Price  shall be
required in the case of the issuance by the Company of Common Stock (i) pursuant
to the  exercise of any  warrant;  (ii)  pursuant  to the  exercise of any stock
options or warrants  currently  outstanding or securities  issued after the date
hereof,  which may be approved by the Company's  Board of Directors  pursuant to
any Company  benefit plan or exercised,  under any employee  benefit plan of the
Company to officers, directors,  consultants or employees, but only with respect
to such warrants or stock options as are exercisable at prices no lower than the
closing bid price of the Common Stock as of the date of grant thereof.


953108.1  5/12/2000  10:52a            -3-

<PAGE>



                  e. In case of any capital  reorganization or reclassification,
or any  consolidation  or merger to which the  Company  is a party  other than a
merger or consolidation in which the Company is the continuing  corporation,  or
in case of any sale or  conveyance  to  another  entity of the  property  of the
Company as an entirety  or  substantially  as a entirety,  or in the case of any
statutory  exchange  of  securities  with  another  corporation  (including  any
exchange  effected in connection with a merger of a third  corporation  into the
Company),  the Holder of this Warrant shall have the right thereafter to receive
on the exercise of this Warrant the kind and amount of securities, cash or other
property  which the Holder  would have  owned or have been  entitled  to receive
immediately after such reorganization, reclassification,  consolidation, merger,
statutory  exchange,   sale  or  conveyance  had  this  Warrant  been  exercised
immediately   prior   to   the   effective   date   of   such    reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
and in any such case, if necessary,  appropriate adjustment shall be made in the
application  of the  provisions  set forth in this Section 3 with respect to the
rights and  interests  thereafter  of the Holder of this Warrant to the end that
the provisions set forth in this Section 3 shall thereafter  correspondingly  be
made  applicable,  as nearly as may  reasonably be, in relation to any shares of
stock or other securities or property thereafter  deliverable on the exercise of
this Warrant. The above provisions of this Section 3(e) shall similarly apply to
successive   reorganizations,   reclassifications,    consolidations,   mergers,
statutory exchanges, sales or conveyances.  The Company shall require the issuer
of any shares of stock or other securities or property thereafter deliverable on
the exercise of this Warrant to be  responsible  for all of the  agreements  and
obligations  of  the  Company  hereunder.  Notice  of any  such  reorganization,
reclassification,  consolidation, merger, statutory exchange, sale or conveyance
and of said provisions so proposed to be made, shall be mailed to the Holders of
the Warrants  not less than thirty (30) days prior to such event.  A sale of all
or substantially all of the assets of the Company for a consideration consisting
primarily  of  securities  shall be deemed a  consolidation  or  merger  for the
foregoing purposes.

                  f. No  adjustment  in the Per  Share  Warrant  Price  shall be
required  unless  such  adjustment  would  require an increase or decrease of at
least $0.05 per share of Common Stock;  provided,  however, that any adjustments
which by reason of this  Subsection  3(g) are not  required  to be made shall be
carried forward and taken into account in any subsequent  adjustment;  provided,
further, however, that adjustments shall be required and made in accordance with
the  provisions  of this Section 3 (other than this  Subsection  3(g)) not later
than such time as may be required in order to preserve the tax-free  nature of a
distribution  to the Holder of this  Warrant or Common Stock  issuable  upon the
exercise  hereof.  All  calculations  under this  Section 3 shall be made to the
nearest cent or to the nearest  1/100th of a share, as the case may be. Anything
in this Section 3 to the contrary notwithstanding, the Company shall be entitled
to make such  reductions  in the Per Share Warrant  Price,  in addition to those
required by this Section 3, as it in its  discretion  shall deem to be advisable
in order  that any stock  dividend,  subdivision  of shares or  distribution  of
rights to purchase  stock or securities  convertible or  exchangeable  for stock
hereafter made by the Company to its stockholders shall not be taxable.

                  g.  Whenever  the Per  Share  Warrant  Price  is  adjusted  as
provided in this Section 3 and upon any  modification  of the rights of a Holder
of Warrants in accordance with this Section 3,

953108.1  5/12/2000  10:52a           -4-

<PAGE>



the Company shall promptly  prepare a brief  statement of  the  facts  requiring
such adjustment or  modification  and the manner of computing the same and cause
copies of such  certificate  to be mailed to the  Holders of the  Warrants.  The
Company may, but shall not be obligated to unless requested by a Majority of the
Holders,  obtain, at its expense,  a certificate of a firm of independent public
accountants of recognized  standing  selected by the Board of Directors (who may
be the regular  auditors of the  Company)  setting  forth the Per Share  Warrant
Price and the number of Warrant  Shares in effect after such  adjustment  or the
effect of such  modification,  a brief  statement  of the facts  requiring  such
adjustment or modification and the manner of computing the same and cause copies
of such certificate to be mailed to the Holders of the Warrants.

                  h. If the Board of Directors of the Company  shall declare any
dividend or other  distribution  with  respect to the Common  Stock other than a
cash  distribution out of earned surplus,  the Company shall mail notice thereof
to the Holders of the  Warrants  not less than ten (10) days prior to the record
date fixed for determining stockholders entitled to participate in such dividend
or other distribution.

                  i. If,  as a result of an  adjustment  made  pursuant  to this
Section 3, the Holder of any Warrant  thereafter  surrendered for exercise shall
become  entitled to receive  shares of two or more  classes of capital  stock or
shares of Common  Stock and other  capital  stock of the  Company,  the Board of
Directors (whose  determination  shall be conclusive and shall be described in a
written  notice to the Holder of any  Warrant  promptly  after such  adjustment)
shall  determine the  allocation of the adjusted Per Share Warrant Price between
or among shares or such  classes of capital  stock or shares of Common Stock and
other capital stock.

                  j. Upon the  expiration  of any rights,  options,  warrants or
conversion privileges with respect to the issuance of which an adjustment to the
Per Share Warrant  Price had been made,  if such shall not have been  exercised,
the number of Warrant Shares  purchasable upon exercise of this Warrant,  to the
extent this Warrant has not then been exercised, shall, upon such expiration, be
readjusted  and shall  thereafter  be such as they would have been had they been
originally  adjusted (or had the original  adjustment not been required,  as the
case may be) on the basis of (A) the fact that Common  Stock,  if any,  actually
issued or sold upon the exercise of such rights, options, warrants or conversion
privileges,  and (B) the fact that such  shares of Common  Stock,  if any,  were
issued or sold for the consideration  actually received by the Company upon such
exercise plus the  consideration,  if any,  actually received by the Company for
the issuance, sale or grant of all such rights, options,  warrants or conversion
privileges  whether  or  not  exercised;   provided,   however,   that  no  such
readjustment  shall have the effect of decreasing  the number of Warrant  Shares
purchasable  upon  exercise of this Warrant by an amount in excess of the amount
of the adjustment  initially  made in respect of the issuance,  sale or grant of
such rights, options, warrants or conversion privileges.

                  k. In case  any  event  shall  occur  as  to  which  the other
provisions  of this  Section 3 are not  strictly  applicable but as to which the
failure to make any  adjustment  would not fairly  protect the  purchase  rights
represented  by  this  Warrant  in  accordance  with  the  essential  intent and
principles hereof then, in each such case, the Board of Directors of the Company
shall in good faith determine

953108.1  5/12/2000  10:52a            -5-

<PAGE>



the adjustment, if any,  on a basis  consistent  with the  essential  intent and
principles  established  herein,  necessary  to  preserve  the  purchase  rights
represented by the Warrants. Upon such determination,  the Company will promptly
mail a copy thereof to the Holder of this Warrant and shall make the adjustments
described therein.

                  4. Fully Paid  Stock;  Taxes.  The shares of the Common  Stock
represented by each and every  certificate for Warrant Shares delivered upon the
exercise of this Warrant shall at the time of such delivery, be duly authorized,
validly issued and outstanding, fully paid and nonassessable, and not subject to
preemptive rights or rights of first refusal, and the Company will take all such
actions as may be necessary  to assure that the par value,  if any, per share of
the  Common  Stock  is at all  times  equal to or less  than the then Per  Share
Warrant Price. The Company shall pay all documentary, stamp or similar taxes and
other  similar  governmental  charges  that may be imposed  with  respect to the
issuance or delivery of any Common Shares upon  exercise of the Warrants  (other
than  income  taxes);  provided,  however,  that if the Common  Shares are to be
delivered in a name other than the name of the Holder, no such delivery shall be
made unless the person requesting the same has paid to the Company the amount of
transfer taxes or charges incident thereto, if any.

                  5.  Registration  Under Securities Act of 1933.  a. The Holder
shall  have the right to  participate  in the  registration  rights  granted  to
Holders of  Registrable  Securities (as defined in the  Subscription  Agreement)
with respect to the Warrant Shares.

                  b.  Until all of the  Warrant  Shares  have been sold  under a
registration  statement  declared  effective  by  the  Securities  and  Exchange
Commission  or pursuant to Rule 144, the Company shall use its  reasonable  best
efforts to file with the Securities and Exchange  Commission all current reports
and the  information as may be necessary to enable the Holder to effect sales of
its shares in reliance upon Rule 144  promulgated  under the  Securities  Act of
1933, as amended (the "Act").

                  6. Investment Intent; Limited Transferability.   a. The Holder
represents, by accepting this Warrant, that it understands that this Warrant and
any securities obtainable upon exercise of this Warrant have not been registered
for sale under Federal or state  securities  laws and are being offered and sold
to  the  Holder  pursuant  to one  or  more  exemptions  from  the  registration
requirements  of  such   securities   laws.  In  the  absence  of  an  effective
registration of such securities or an exemption therefrom,  any certificates for
such  securities  shall bear the legend set forth on the first page hereof.  The
Holder understands that it must bear the economic risk of its investment in this
Warrant and any  securities  obtainable  upon  exercise  of this  Warrant for an
indefinite  period of time,  as this Warrant and such  securities  have not been
registered  under Federal or state  securities laws and therefore cannot be sold
unless  subsequently  registered under such laws,  unless an exemption from such
registration is available.

                  b. The Holder,  by its acceptance of this Warrant,  represents
to the Company that it is acquiring this Warrant and will acquire any securities
obtainable upon exercise of this Warrant

953108.1  5/12/2000  10:52a             -6-

<PAGE>



for its own  account  for  investment  and not  with a view  to,  or for sale in
connection  with, any  distribution  thereof in violation of the Act. The Holder
agrees that this Warrant and any such  securities  will not be sold or otherwise
transferred unless (i) a registration statement with respect to such transfer is
effective  under the Act and any applicable  state  securities laws or (ii) such
sale or transfer is made pursuant to one or more exemptions from the Act.

                  c. In addition to the limitations set forth in Section 1, this
Warrant may not be sold,  transferred,  assigned or  hypothecated  by the Holder
except in compliance  with the  provisions of the Act and the  applicable  state
securities  "blue sky" laws, and is so  transferable  only upon the books of the
Company which it shall cause to be maintained for such purpose.  The Company may
treat the registered Holder of this Warrant as he or it appears on the Company's
books at any time as the Holder for all  purposes.  The Company shall permit any
Holder of a Warrant or his duly authorized attorney, upon written request during
ordinary  business  hours,  to inspect and copy or make  extracts from its books
showing  the  registered  holders of  Warrants.  All  Warrants  issued  upon the
transfer  or  assignment  of this  Warrant  will be dated  the same date as this
Warrant, and all rights of the holder thereof shall be identical to those of the
Holder.

                  d. The Holder has been  afforded  (i) the  opportunity  to ask
such  questions  as it has deemed  necessary  of, and to receive  answers  from,
representatives  of the  Company  concerning  the  terms and  conditions  of the
Warrants or the exercise of the Warrants;  and (ii) the  opportunity  to request
such additional  information  which the Company possesses or can acquire without
unreasonable effort or expense.

                  e. The Holder did not (i) receive or review any advertisement,
article,  notice or other communication  published in a newspaper or magazine or
similar media or broadcast over television or radio,  whether closed circuit, or
generally  available;  or (ii) attend any seminar,  meeting or investor or other
conference  whose  attendees  were, to such Holder's  knowledge,  invited by any
general solicitation or general advertising.

                  f. The Holder is an "accredited  investor"  within the meaning
of Regulation D under the Act. Such Holder is acquiring the Warrants for its own
account  and not with a present  view to, or for sale in  connection  with,  any
distribution  thereof  in  violation  of the  registration  requirements  of the
Securities  Exchange Act of 1934, without prejudice,  however,  to such Holder's
right, subject to the provisions of the Subscription Agreement and this Warrant,
at all times to sell or  otherwise  dispose of all or any part of such  Warrants
and Warrant Shares.

                  g. Either by reason of such  Holder's  business  or  financial
experience or the business or financial experience of its professional  advisors
(who are  unaffiliated  with and who are not  compensated  by the Company or any
affiliate, finder or selling agent of the Company, directly or indirectly), such
Holder has the capacity to protect such Holder's  interests in  connection  with
the transactions contemplated by this Warrant and the Purchase Agreement.


953108.1  5/12/2000  10:52a             -7-

<PAGE>



                  7.  Optional  Redemption.  In the event that the  closing  bid
price for the Common Stock for any 20 Trading Days in any 30 consecutive Trading
Day period is at least  200% of the Per Share  Warrant  Price  (the  "Redemption
Price"),  the Company shall be entitled to redeem the Warrants,  or any of them,
at a per Warrant  redemption price of $0.01, by 30 business days' written notice
to the Holder.  Upon the expiration of such 30 business day period, all Warrants
noticed for redemption  that have not  theretofore  been exercised by the Holder
shall,  upon  payment  of the  aggregate  redemption  price  therefor,  cease to
represent  the right to purchase  any shares of Common Stock and shall be deemed
cancelled without any further act or deed on the part of the Company. The Holder
undertakes to return the certificate  representing any redeemed  Warrants to the
Company upon their  redemption  and to indemnify the Company with respect to any
losses,  claims,  damages or  liabilities  arising from the Holder's  failure to
return such certificate.  In the event the certificate so returned  represents a
number of Warrants in excess of the number being redeemed,  the Company shall as
promptly as practicable  issue to the Holder a new certificate for the number of
unredeemed Warrants.

                  8.  Loss,   etc.,   of  Warrant.   Upon  receipt  of  evidence
satisfactory  to the Company of the loss,  theft,  destruction  or mutilation of
this Warrant, and of indemnity reasonably  satisfactory to the Company, if lost,
stolen or destroyed,  and upon surrender and  cancellation  of this Warrant,  if
mutilated,  the Company shall execute and deliver to the Holder a new Warrant of
like date, tenor and denomination.

                  9.  Warrant  Holder Not  Stockholder.  This  Warrant  does not
confer upon the Holder any right to vote on or consent to or receive notice as a
stockholder of the Company, as such, in respect of any matters  whatsoever,  nor
any other rights or liabilities as a stockholder,  prior to the exercise hereof;
this Warrant  does,  however,  require  certain  notices to Holders as set forth
herein.

                  10. Communication. No notice or other communication under this
Warrant shall be effective unless, but any notice or other  communication  shall
be  effective  and shall be deemed to have been given if, the same is in writing
and is mailed by first-class mail, postage prepaid, addressed to:

                  a. the Company at Discovery Laboratories, Inc., 350 South Main
Street, Suite 307, Doylestown,  Pennsylvania 18901, Attn: Evan  Myrianthopoulos,
Vice President of Finance or such other address as the Company has designated in
writing to the Holder, or

                  b. the Holder at its address on the books of the  Company,  or
other such address as the Holder has designated in writing to the Company.

                  11. Headings.  The headings of this Warrant have been inserted
as a matter of convenience and shall not affect the construction hereof.


953108.1  5/12/2000  10:52a            -8-

<PAGE>



                  12.  Applicable  Law.  This  Warrant  shall be governed by and
construed in accordance  with the laws of the State of Delaware  without  giving
effect to the principles of conflicts of law thereof.

                  13.  Amendment,  Waiver,  etc.  Except as  expressly  provided
herein,  neither  this  Warrant  nor any term  hereof  may be  amended,  waived,
discharged or terminated other than by a written  instrument signed by the party
against whom enforcement of any such amendment, waiver, discharge or termination
is sought; provided, however, that any provisions hereof may be amended, waived,
discharged  or  terminated  upon the  written  consent  of the  Company  and the
Majority of the Holders.

                  IN WITNESS WHEREOF,  the Company has caused this Warrant to be
executed this 21st day of March, 2000.

                         DISCOVERY LABORATORIES, INC.


                         By:
                                  Name:  Robert J. Capetola, Ph.D.
                                  Title:  President and Chief Executive Officer


953108.1  5/12/2000  10:52a             -9-

<PAGE>


                                  SUBSCRIPTION


                  The   undersigned,   ___________________,   pursuant   to  the
provisions of the foregoing Warrant, hereby agrees to subscribe for and purchase
____________________  shares of the Common Stock,  par value $.001 per share, of
Discovery Laboratories, Inc. covered by said Warrant, and makes payment therefor
in full at the price per share provided by said Warrant.


Dated:  ______________________       Signature:

                                     Address:


                                   ASSIGNMENT

                  FOR VALUE RECEIVED  _______________  hereby sells, assigns and
transfers  unto  ____________________  the  foregoing  Warrant  and  all  rights
evidenced    thereby,    and   does    irrevocably    constitute   and   appoint
_____________________,  attorney,  to  transfer  said  Warrant  on the  books of
Discovery Laboratories, Inc.


Dated:  ______________________       Signature:

                                     Address:


                               PARTIAL ASSIGNMENT

                  FOR  VALUE   RECEIVED   _______________   hereby  assigns  and
transfers  unto  ____________________  the right to purchase  _______  shares of
Common Stock, par value $.001 per share, of Discovery Laboratories, Inc. covered
by the  foregoing  Warrant,  and a  proportionate  part of said  Warrant and the
rights  evidenced   thereby,   and  does  irrevocably   constitute  and  appoint
____________________,  attorney,  to transfer  such part of said  Warrant on the
books of the Company.


Dated:  ______________________       Signature:

                                     Address:


953108.1  5/12/2000  10:52a            -10-


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION FROM DISCOVERY
     LABORATORIES, INC. FORM 10-QSB FOR THE PERIOD ENDED MARCH 31, 2000 AND
     IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER>                                   1

<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                              DEC-31-2000
<PERIOD-START>                                 JAN-01-2000
<PERIOD-END>                                   MAR-31-2000
<CASH>                                         23,591,000
<SECURITIES>                                   0
<RECEIVABLES>                                  0
<ALLOWANCES>                                   0
<INVENTORY>                                    575,000
<CURRENT-ASSETS>                               24,288,000
<PP&E>                                         664,000
<DEPRECIATION>                                 217,000
<TOTAL-ASSETS>                                 24,753,000
<CURRENT-LIABILITIES>                          1,745,000
<BONDS>                                        0
                          0
                                    0
<COMMON>                                       21,000
<OTHER-SE>                                     22,943,000
<TOTAL-LIABILITY-AND-EQUITY>                   24,753,000
<SALES>                                        19,000
<TOTAL-REVENUES>                               41,000
<CGS>                                          0
<TOTAL-COSTS>                                  0
<OTHER-EXPENSES>                               1,509,000
<LOSS-PROVISION>                               0
<INTEREST-EXPENSE>                             2,000
<INCOME-PRETAX>                                (1,470,000)
<INCOME-TAX>                                   0
<INCOME-CONTINUING>                            0
<DISCONTINUED>                                 0
<EXTRAORDINARY>                                0
<CHANGES>                                      0
<NET-INCOME>                                   (1,470,000)
<EPS-BASIC>                                    (0.12)
<EPS-DILUTED>                                  (0.12)


</TABLE>


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