HEMISPHERX BIOPHARMA INC
SC 13G/A, 1997-04-29
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G
                                 (Rule 13d-102)

             INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2
                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                               (Amendment No. 1) *

                           HEMISPHERX BIOPHARMA, INC.
                                (Name of Issuer)

                          COMMON STOCK, $.001 PAR VALUE
                         (Title of Class of Securities)

                                    42366C103
                                 (CUSIP Number)

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

<PAGE>

CUSIP No. 42366C103


1) Names of Reporting Persons,  S. S. or I. R. S.  Identification  Nos. of Above
Persons

              Harris Freedman

2) Check the Appropriate Box if a Member of a Group (See Instructions)

          (a) N/A

          (b) N/A

3) SEC Use Only

4) Citizenship or Place of Organization: United States of America


Number of Shares         (5) Sole  Voting  Power:  1,227,328  shares  of  Common
                         Stock. Bridge Ventures,  Inc., of which Mr. Freedman is
                         an officer,  has given an irrevocable  proxy to William
                         A.  Carter,  president  of the  issuer,  to vote 50,000
                         shares of Common Stock. (See Exhibit 1)

Owned by Each
Reporting Person
With                     (6) Shared Voting Power: N/A

                         (7) Sole Dispositive Power:  1,285,328 shares of Common
                         Stock

                         (8) Shared Dispositive Power: N/A

9) Aggregate  Amount  Beneficially  Owned by Each  Reporting  Person:  1,285,328
shares of Common Stock

10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares: N/A

11) Percent of Class Represented by Amount in Row (9): 7.4%

12) Type of Reporting Person: IN

                                        2

<PAGE>

Item 1.

     1(a). Name of Issuer. Hemispherx Biopharma, Inc.

     1(b). Address of Issuer's Principal Executive Offices.

                       Hemispherx Biopharma, Inc.
                       1617 JFK Boulevard
                       Philadelphia, Pennsylvania 19103

Item 2.

     2(a). Name of Person Filing. Harris Freedman

     2(b). Address of Principal Business Office.

                       Bridge Ventures, Inc.
                       545 Madison Avenue, 15th Floor
`                      New York, New York 10022

     2(c). Citzenship. United States of America

     2(d). Title of Class of Securities. Common Stock, $.001 par value.

     2(e). CUSIP Number. 42366C103

Item 3. N/A

Item 4. Ownership.

     (a) Amount Beneficially Owned: 1,285,328

     (b) Percent of Class: 7.4%

     (c)  (i) Mr. Freedman  possesses the sole power to vote and direct the vote
          of 1,227,328 shares of Common Stock.  Bridge Ventures,  Inc., of which
          Mr. Freedman is an officer,  has given an irrevocable proxy to William
          A. Carter,  president of the issuer,  to vote 50,000  shares of Common
          Stock. (See Exhibit 1)

          (ii) Mr.  Freedman  possesses  the sole power to dispose and to direct
          the disposition of 1,285,328 shares of Common Stock.

Item 5. Ownership of Five Percent or Less of a Class. N/A

Item 6. Ownership of More than Five Percent on Behalf of Another Person. N/A

                                        3

<PAGE>

Item 7.  Identification  and Classification of the Subsidiary Which Acquired the
         Security Being Reported on by the Parent Holding Company. N/A

Item 8. Identification and Classification of Members of a Group. N/A

Item 9. Notice of Dissolution of Group: N/A

Item 10. Certification:

     By signing  below I certify  that,  to the best of my knowledge and belief,
the  securities  referred  to above  were  acquired  in the  ordinary  course of
business  and were not acquired for the purpose of and do not have the effect of
changing or  influencing  the control of the issuer of such  securities and were
not acquired in connection with or as a participant in any transaction have such
purpose or effect.

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.

                                                 April 10, 1997
                                      ---------------------------------------
                                                     (Date)

                                             /s/ Harris Freedman
                                      ---------------------------------------
                                                   (Signature)

                                                 Harris Freedman
                                      ---------------------------------------
                                                   (Name/Title)

     The original  statement  shall be signed by each person on whose behalf the
statement is filed or his authorized representative.  If the statement is signed
on behalf of a person by his authorized  representative (other than an executive
officer  or  general   partner  of  this   filing   person),   evidence  of  the
representative's  authority to sign on behalf of such person shall be filed with
the  statement,  provided,  however,  that a power of attorney  for this purpose
which is already on file with the Commission may be  incorporated  by reference.
The name and any title of each person who signs the statement  shall be typed or
printed beneath his signature.

Attention:  Intentional  misstatements  or omissions of fact constitute  Federal
criminal violations (See 18 U. S. C. 1001).


                                        4


          Irrevocable Proxy to Vote Shares of HEM Pharmaceuticals Corp.
                           to William A. Carter, M.D.

     In  consideration  for the sale of 50,000 shares of common stock, par value
$.001  per  share  (the  "Shares")  of HEM  Pharmaceuticals  Corp.,  a  Delaware
corporation  (the  "Company")  in  connection  with the Common  Stock  Financing
conducted by the Company in 1994, the undersigned  hereby  irrevocably  appoints
William A. Carter,  M.D.,  Chief Executive  Officer and Chairman of the Board of
the Company as proxy with full power of  substitution  to vote all Shares in the
name of the  undersigned on any matter to be voted upon by the  stockholders  of
the  Company  until such time as (i) the  Company  shall have  achieved a market
capitalization  of $300,000,000  or greater for at least 20 consecutive  days of
trading in the public  markets,  or (ii) the Company  shall have received a bona
fide offer for  acquisition  of merger,  the net effect of which if  consummated
would be to  establish a market  capitalization  of the Company of not less than
$300,000,000.

     In no  event  shall  this  Irrevocable  Proxy  restrict  the  sale  by  the
undersigned of all or any portion of the Shares in a public sale, for value,  in
an arm's  length  transaction  and the sale of all or any  portion of the Shares
upon such terms shall be free and clear of this Irrevocable Proxy.

     This  Irrevocable  Proxy is an  agency  coupled  with an  interest  and all
authority  conferred  hereby  shall be  irrevocable,  and,  except as  expressly
provided  herein,  shall not be terminated by any act of the  undersigned  or by
operation  of law,  whether by the death or  incapacity  of the  undersigned  or
otherwise,  or by the  termination  of any  trust  or  estate,  by the  death or
incapacity of one or more trustees, guardians, executors or administrators under
such trust or estate,  by the  dissolution,  winding up or  liquidation or other
termination of existence of any  corporation or partnership or by the occurrence
of any other event. If after the execution hereof the undersigned  should die or
become incapacitated,  or if any trust or estate should be terminated, or if any
corporation  or partnership  should be dissolved or liquidated,  or if any other
such event should occur,  before the completion of the  conditions  contemplated
hereby  instructions  shall be delivered by or on behalf of the  undersigned  in
accordance with the terms and conditions hereof, and actions taken by William A.
Carter,  M.D.  pursuant to this  Irrevocable  Proxy shall be as valid as if such
death,  incapacity,  termination,  dissolution  or other event had not  occurred
regardless of whether or not William A. Carter,  M.D. shall have received notice
of such  death,  incapacity,  termination,  dissolution  or  other  event.  This
Irrevocable  Proxy  shall  be  binding  on  the  respective  heirs,   executors,
successors or assigns of the undersigned.  This irrevocable proxy is intended to
revoke any prior  proxy(s)  including  any proxy which may have been  granted or
delivered to Bridge Ventures, Inc. and is effective as of September 8, 1994.

AGREED TO AND ACCEPTED BY:              STOCKHOLDER
BRIDGE VENTURES, INC.

BY: /s/ Harris Freedman                 By: /s/ Jerome Belson
   -----------------------                 -----------------------
    Harris Freedman                         Jerome Belson
    Secretary                               495 Broadway, 6th floor
                                            New York, NY 10012



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