VIROPHARMA INC
4, 1997-07-10
PHARMACEUTICAL PREPARATIONS
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 4
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
( ) Check this box if no longer subject to Section 16.
Form 4 or Form 5 obligations may continue. See Instructions 1(b).
1. Name and Address of Reporting Person
   Dow, Stephen M.
   c/o Sevin Rosen Fund IV L.P.
   13455 Noel Road
   Suite 1670
   Dallas, TX  75240
2. Issuer Name and Ticker or Trading Symbol
   ViroPharma Incorporated
   VPHM
3. IRS or Social Security Number of Reporting Person (Voluntary)
   
4. Statement for Month/Year
   June 1997
5. If Amendment, Date of Original (Month/Year)
   
6. Relationship of Reporting Person(s) to Issuer (Check all applicable)
   (X) Director (X) 10% Owner ( ) Officer (give title below) ( ) Other
   (specify below)
   
7. Individual or Joint/Group Filing (Check Applicable Line)
   ( ) Form filed by One Reporting Person
   ( ) Form filed by More than One Reporting Person
<TABLE>
<CAPTION>
___________________________________________________________________________________________________________________________________
 Table I -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned                                                 |
___________________________________________________________________________________________________________________________________|
1. Title of Security       |2.    |3.    |4.Securities Acquired (A)         |5.Amount of        |6.Dir |7.Nature of Indirect       |
                           | Transaction |  or Disposed of (D)              |  Securities       |ect   |  Beneficial Ownership     |
                           |      |      |                                  |  Beneficially     |(D)or |                           |
                           |      |    | |                  | A/|           |  Owned at         |Indir |                           |
                           | Date |Code|V|    Amount        | D |    Price  |  End of Month     |ect(I)|                           |
___________________________________________________________________________________________________________________________________|
<S>                        <C>    <C>  <C><C>               <C> <C>         <C>                 <C>    <C>
Common Stock, par value $.0|06/23/|X   | |22,437            |A  |$1.96 per s|1,258,727          |I     |By Sevin Rosen Fund IV LP (|
02 per share               |97    |    | |                  |   |hare       |                   |      |"SRF")(1)                  |
- -----------------------------------------------------------------------------------------------------------------------------------|
Common Stock, par value $.0|      |    | |                  |   |           |6,233              |I     |By Sevin Rosen Bayless Mgmt|
02 per share               |      |    | |                  |   |           |                   |      |.                          |
- -----------------------------------------------------------------------------------------------------------------------------------|
                           |      |    | |                  |   |           |                   |      |Co. ("SRB")(1)             |
- -----------------------------------------------------------------------------------------------------------------------------------|
Common Stock, par value $.0|      |    | |                  |   |           |14,000             |I     |By The Dow Family Trust (2)|
02 per share               |      |    | |                  |   |           |                   |      |                           |
- -----------------------------------------------------------------------------------------------------------------------------------|
___________________________________________________________________________________________________________________________________|
<CAPTION>
___________________________________________________________________________________________________________________________________
 Table II -- Derivative Securitites Acquired, Disposed of, or Beneficially Owned                                                   |
___________________________________________________________________________________________________________________________________|
1.Title of Derivative |2.Con-  |3.   |4.    |5.Number of De |6.Date Exer|7.Title and Amount  |8.Price|9.Number    |10.|11.Nature of|
  Security            |version |Transaction | rivative Secu |cisable and|  of Underlying     |of Deri|of Deriva   |Dir|Indirect    |
                      |or Exer |     |      | rities Acqui  |Expiration |  Securities        |vative |tive        |ect|Beneficial  |
                      |cise    |     |      | red(A) or Dis |Date(Month/|                    |Secu   |Securities  |(D)|Ownership   |
                      |Price of|     |      | posed of(D)   |Day/Year)  |                    |rity   |Benefi      |or |            |
                      |Deriva- |     |      |               |Date |Expir|                    |       |ficially    |Ind|            |
                      |tive    |     |      |           | A/|Exer-|ation|   Title and Number |       |Owned at    |ire|            |
                      |Secu-   |     |    | |           | D |cisa-|Date |   of Shares        |       |End of      |ct |            |
                      |rity    |Date |Code|V|  Amount   |   |ble  |     |                    |       |Month       |(I)|            |
___________________________________________________________________________________________________________________________________|
<S>                   <C>      <C>   <C>  <C><C>        <C> <C>   <C>   <C>          <C>     <C>     <C>          <C> <C>
Warrants (right to acq|$1.96 pe|06/23|X   | |2          |D  |Immed|(4)  |Common Stock|22,437 |       |0           |I  |By SRF(1)   |
uire Common Stock)    |r share |/97  |    | |           |   |.    |     |            |       |       |            |   |            |
                      |(3)     |     |    | |           |   |     |     |            |       |       |            |   |            |
- -----------------------------------------------------------------------------------------------------------------------------------|
                      |        |     |    | |           |   |     |     |            |       |       |            |   |            |
___________________________________________________________________________________________________________________________________|
</TABLE>
Explanation of Responses:
(1)  All securities are owned by SRF and SRB.  Mr. Dow is a general partner of 
SRB Associates IV L.P., general 
partner of SRF, and an officer of SRB.  Mr. Dow shares voting and investment 
power with the other general 
partners and officers, as applicable.  Mr. Dow disclaims beneficial ownership 
of such securities except to the 
extent of his pecuniary interest therein, and this report shall not be deemed 
an admission that Mr. Dow is the 
beneficial owner of such securities for purposes of Section 16 or any other 
purpose.
(2) The shares were purchased by The Dow Family Trust, of which Mr. Dow and his 
spouse are trustees and he 
and members of his immediate family are the 
beneficiaries.
(3)  The Warrants were exercised on a cashless basis pursuant to the terms of 
the Warrants.
(4)  Upon the earlier of (March 3, 2002 and May 12, 2002, respectively) or the 
consummation of a qualified public 
offering, as described in the 
Warrants.
SIGNATURE OF REPORTING PERSON
/s/ John V. Jaggers, as Attorney-in-Fact
DATE
July 10, 1997



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