<PAGE>
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
(RULE 13D-102)
INFORMATION TO BE INCLUDED IN STATEMENT(S) FILED PURSUANT TO RULES 13D-1(B), (C)
AND (D) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13D-2(B)
AMENDMENT NO. 2
VIROPHARMA INCORPORATED
---------------------------------------------
(Name of Issuer)
COMMON STOCK, $.002 PAR VALUE PER SHARE
---------------------------------------------
(Title of Class of Securities)
928241-10-8
---------------------------------------------
(CUSIP Number)
DECEMBER 31, 1998
---------------------------------------------
(Date of Event Which Requires Filing of This Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[_] Rule 13d-1(b)
[_] Rule 13d-1(c)
[X] Rule 13d-1(d)
Page 1 of 13 Pages
An Index of Exhibits Appears On Page 13
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CUSIP NO. 928241-10-8 13G PAGE 2 OF 13 PAGES
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AMENDMENT NO. 2
- ------------------------------------------------------------------------------
NAME OF REPORTING PERSON
1 S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
FRAZIER HEALTHCARE II, L.P. FEIN: 91-1689734
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Organized under the laws of the State of Delaware
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
0
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
OWNED BY 192,581
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
0
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
192,581
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
192,581
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
1.7%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
LP
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 2 of 13 Pages
An Index of Exhibits Appears On Page 13
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CUSIP NO. 928241-10-8 13G PAGE 3 OF 13 PAGES
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AMENDMENT NO. 2
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NAME OF REPORTING PERSON
1 S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
FHM II, L.L.C. FEIN: 91-1689731
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Organized under the laws of the State of Delaware
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
0
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
OWNED BY 192,581
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
0
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
192,581
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
192,581
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
1.7%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
LLC
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 3 of 13 Pages
An Index of Exhibits Appears On Page 13
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CUSIP NO. 928241-10-8 13G PAGE 4 OF 13 PAGES
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AMENDMENT NO. 2
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NAME OF REPORTING PERSON
1 S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
FRAZIER MANAGEMENT, L.L.C. FEIN: 91-1678546
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Organized under the laws of the State of Delaware
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
0
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
OWNED BY 192,581
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
0
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
192,581
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
192,581
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
1.7%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
LLC
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
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An Index of Exhibits Appears On Page 13
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CUSIP NO. 928241-10-8 13G PAGE 5 OF 13 PAGES
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AMENDMENT NO. 2
- ------------------------------------------------------------------------------
NAME OF REPORTING PERSON
1 S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
FRAZIER & COMPANY, INC. FEIN: 91-1526760
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Organized under the laws of the State of Washington
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
0
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
OWNED BY 192,581
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
0
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
192,963
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
192,963
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
1.7%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
CO
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 5 of 13 Pages
An Index of Exhibits Appears On Page 13
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CUSIP NO. 928241-10-8 13G PAGE 6 OF 13 PAGES
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AMENDMENT NO. 2
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NAME OF REPORTING PERSON
1 S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Alan D. Frazier SS####-##-####
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
United States Citizen
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF
0
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
OWNED BY 192,963
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING
0
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
192,963
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
192,963
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
11
1.7%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
IN
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 6 of 13 Pages
An Index of Exhibits Appears On Page 13
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AMENDMENTS TO SCHEDULE 13G
ITEM 1(A). NAME OF ISSUER.
This Schedule 13G relates to ViroPharma Incorporated, a Delaware
corporation (the "Company").
ITEM 1(B). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
The Company's principal executive offices are located at 76 Great Valley
Parkway, Malvern, PA 19355.
ITEM 2(A). NAME OF PERSONS FILING.
This Schedule 13G relates to each of the following persons:
. Frazier Healthcare II, L.P., a limited partnership ("FHII")
. FHM II, L.L.C., a limited liability company ("FHMII")
. Frazier Management, L.L.C., a limited liability company ("FMLLC")
. Frazier & Company, Inc., a Washington corporation ("F&C Inc.")
. Alan D. Frazier, as a director and sole shareholder of F&C Inc.
The general partner of FHII is FHMII, whose managing member is FMLLC. The
managing member of FMLLC is F&C Inc. The sole shareholder of F&C Inc. is Alan D.
Frazier.
ITEM 2(B). ADDRESS OF PRINCIPAL BUSINESS OFFICE.
The business address of each of the reporting persons is 601 Union Street,
Suite 3300, Seattle, Washington 98101.
ITEM 2(C). CITIZENSHIP.
FHII is a limited partnership organized under the laws of the State of
Delaware. FHMII and FMLLC are limited liability companies organized under the
laws of the State of Delaware. F&C Inc. is a corporation organized under the
laws of the State of Washington. Mr. Frazier is a United States citizen.
ITEM 2(D). TITLE OF CLASS OF SECURITIES.
This Schedule 13G relates to the Company's common stock, $.002 par value
per share (the "Common Stock").
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ITEM 2(E). CUSIP NUMBER.
The CUSIP Number for the Company's Common Stock is 928241-10-8.
ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13D-1(B) OR 13D-2(B),
CHECK WHETHER THE PERSON FILING IS A:
(a) [_] Broker or dealer registered under Section 15 of the Act,
(b) [_] Bank as defined in Section 3(a)(6) of the Act,
(c) [_] Insurance Company as defined in Section 3(a)(19) of the Act,
(d) [_] Investment Company registered under Section 8 of the Investment Company
Act,
(e) [_] Investment Advisor registered under Section 203 of the Investment
Advisors Act of 1940,
(f) [_] Employee Benefit Plan, Pension Fund which is subject to the provisions
of the Employee Retirement Income Security Act of 1974 or Endowment
Fund,
(g) [_] Parent Holding Company, in accordance with Rule 13d-1(b)(ii)(G),
(h) [_] Group, in accordance with Rule 13d-1(b)(1)(ii)(H).
NOT APPLICABLE
ITEM 4. OWNERSHIP.
The following describes the ownership of Common Stock by FHII, FHMII and
FMLLC as of December 31, 1998:
(a) Amount beneficially owned: 192,581(1)
(b) Percent of class: 1.7%
(c) Number of shares as to which such person has:
(i) Sole power to vote or direct the vote: 0
(ii) Shared power to vote or to direct the vote: 192,581(1)(2)
(iii) Sole power to dispose or to direct the disposition of: 0
(iv) Shared power to dispose or to direct the disposition of:
192,581(1)(2)
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An Index of Exhibits Appears On Page 13
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(1) Represents shares of Common Stock held of record by FHII, of which
FHMII is the general partner. FMLLC is the managing member of FHMII
and F&C Inc. is the managing member of FMLLC. Mr. Frazier is the sole
shareholder of F&C Inc.
(2) Power to vote or to direct the vote of, and power to dispose or to
direct the disposition of, the reported shares is deemed to be shared
among each of FHII, FHMII, FMLLC, F&C Inc. and Mr. Frazier. Each of
such persons denies beneficial ownership of such shares except to the
extent of such person's respective pecuniary interest.
The following describes the ownership of Common Stock by F&C Inc. and Alan
D. Frazier as of December 31, 1998:
(a) Amount beneficially owned: 192,963(1)
(b) Percent of class: 1.7%
(c) Number of shares as to which such person has:
(i) Sole power to vote or direct the vote: 0
(ii) Shared power to vote or to direct the vote: 192,963(1)(2)
(iii) Sole power to dispose or to direct the disposition of: 0
(iv) Shared power to dispose or to direct the disposition of:
192,963(1)(2)
(1) Represents (i) 192,581 shares of Common Stock held of record by FHII,
of which FHMII is the general partner, of which FMLLC is the managing member, of
which F&C Inc. is the managing member, of which Mr. Frazier is the sole
shareholder, and (ii) 382 shares of Common Stock held of record by F&C Inc., of
which Mr. Frazier is the sole shareholder.
(2) Power to vote or to direct the vote of, and power to dispose or direct
the disposition of, the 192,581 shares held of record by FHII is deemed to be
shared among each of FHII, FHMII, FMLLC, F&C Inc. and Mr. Frazier. Each of such
persons denies beneficial ownership of such shares except to the extent of such
person's respective pecuniary interest. Power to vote or to direct the vote of,
and power to dispose or direct the disposition of, the 382 shares held of record
by F&C Inc. is deemed to be shared between F&C Inc. and Mr. Frazier. Mr. Frazier
denies beneficial ownership of such shares.
ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following box: [X]
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ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.
Not applicable.
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.
Not applicable.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP.
Not applicable.
ITEM 10. CERTIFICATION.
Not applicable.
Page 10 of 13 Pages
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SIGNATURE
The undersigned hereby agree that this Schedule is filed on behalf of each
of them and, after reasonable inquiry and to best of their knowledge and belief,
hereby certify that the information set forth in this statement is true,
complete and correct.
Dated: February 9, 1999
FRAZIER HEALTHCARE II, L.P.
By: FHM II, L.L.C.
Its General Partner
By: Frazier Management, L.L.C.
Its Managing Member
By: Frazier & Company, Inc.
Its Managing Member
By /s/ Alan D. Frazier
----------------------------------
Alan D. Frazier, President
FHM II, L.L.C.
By: Frazier Management, L.L.C.
Its Managing Member
By: Frazier & Company, Inc.
Its Managing Member
By /s/ Alan D. Frazier
----------------------------------
Alan D. Frazier, President
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FRAZIER MANAGEMENT, L.L.C.
By: Frazier & Company, Inc.
Its Managing Member
By /s/ Alan D. Frazier
----------------------------------
Alan D. Frazier, President
FRAZIER & COMPANY, INC.
By /s/ Alan D. Frazier
----------------------------------
Alan D. Frazier, President, Director and
Shareholder
/s/ Alan D. Frazier
---------------------------------
Alan D. Frazier
Page 12 of 13 Pages
An Index of Exhibits Appears On Page 13
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EXHIBIT INDEX
(1) Statement required by reporting persons pursuant to Rule 13d-1(k)(1)
(see signature page).
Page 13 of 13 Pages
An Index of Exhibits Appears On Page 13
