UROCOR INC
S-1/A, 1996-05-10
MEDICAL LABORATORIES
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<PAGE>
      AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 10, 1996
                                               REGISTRATION NUMBER 333-3182
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                            ------------------------
 
                                AMENDMENT NO. 2
                                       TO
                                    FORM S-1
                             REGISTRATION STATEMENT
                                     UNDER
                           THE SECURITIES ACT OF 1933
                            ------------------------
 
                                  UROCOR, INC.
             (Exact name of registrant as specified in its charter)
 
<TABLE>
<S>                               <C>                               <C>
            DELAWARE                            8071                           75-2117882
(State or other jurisdiction of     (Primary Standard Industrial    (I.R.S. Employer Identification
 incorporation or organization)     Classification Code Number)                   No.)
</TABLE>
 
                              800 RESEARCH PARKWAY
                         OKLAHOMA CITY, OKLAHOMA 73104
                                  405/290-4000
    (Address, including zip code, and telephone number, including area code,
                  of registrant's principal executive offices)
 
                              WILLIAM A. HAGSTROM
                     PRESIDENT AND CHIEF EXECUTIVE OFFICER
                                  UROCOR, INC.
                              800 RESEARCH PARKWAY
                         OKLAHOMA CITY, OKLAHOMA 73104
                                  405/290-4000
 (Name, address, including zip code, and telephone number, including area code,
                             of agent for service)
                            ------------------------
 
                                   COPIES TO:
 
<TABLE>
<S>                                             <C>
            ROBERT E. WILSON, ESQ.                          MARK P. TANOURY, ESQ.
         FULBRIGHT & JAWORSKI L.L.P.               COOLEY GODWARD CASTRO HUDDLESON & TATUM
          1301 MCKINNEY, SUITE 5100                3000 SAND HILL ROAD, BLDG. 3, SUITE 230
          HOUSTON, TEXAS 77010-3095                      MENLO PARK, CALIFORNIA 94025
                 713/651-5151                                    415/843-5000
</TABLE>
 
                            ------------------------
 
    APPROXIMATE  DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: AS SOON AS
PRACTICABLE AFTER THIS REGISTRATION STATEMENT BECOMES EFFECTIVE.
                            ------------------------
 
    THE REGISTRANT HEREBY  AMENDS THIS  REGISTRATION STATEMENT ON  SUCH DATE  OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL
FILE  A  FURTHER  AMENDMENT  WHICH SPECIFICALLY  STATES  THAT  THIS REGISTRATION
STATEMENT SHALL THEREAFTER BECOME EFFECTIVE  IN ACCORDANCE WITH SECTION 8(A)  OF
THE  SECURITIES ACT  OF 1933, AS  AMENDED, OR UNTIL  THIS REGISTRATION STATEMENT
SHALL BECOME EFFECTIVE ON SUCH DATE  AS THE COMMISSION, ACTING PURSUANT TO  SAID
SECTION 8(A), MAY DETERMINE.
 
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
<PAGE>
                                  UROCOR, INC.
 
                             CROSS-REFERENCE SHEET
                  (PURSUANT TO ITEM 501(B) OF REGULATION S-K)
 
<TABLE>
<CAPTION>
FORM S-1 ITEM AND CAPTION                                                    LOCATION OR PROSPECTUS CAPTION
- ----------------------------------------------------------------  -----------------------------------------------------
<C>        <S>                                                    <C>
       1.  Forepart of the Registration Statement and Outside
            Front Cover Page of Prospectus......................  Facing page of Registration Statement; Cross
                                                                   Reference Sheet; Outside Front Cover Page of
                                                                   Prospectus
       2.  Inside Front and Outside Back Cover Pages of
            Prospectus..........................................  Inside Front Cover and Outside Back Cover Pages of
                                                                   Prospectus
       3.  Summary Information, Risk Factors and Ratio of
            Earnings to Fixed Charges...........................  Prospectus Summary; Risk Factors
       4.  Use of Proceeds......................................  Use of Proceeds; Management's Discussion and Analysis
                                                                   of Financial Condition and Results of Operations
       5.  Determination of Offering Price......................  Underwriting
       6.  Dilution.............................................  Risk Factors; Dilution
       7.  Selling Security Holders.............................                            *
       8.  Plan of Distribution.................................  Outside Front Cover Page of Prospectus; Underwriting
       9.  Description of Securities to Be Registered...........  Capitalization; Description of Capital Stock
      10.  Interests of Named Experts and Counsel...............                            *
      11.  Information with Respect to the Registrant...........  Outside Front Cover Page of Prospectus; Prospectus
                                                                   Summary; Risk Factors; The Company; Use of Proceeds;
                                                                   Dividend Policy; Capitalization; Selected Financial
                                                                   Data; Management's Discussion and Analysis of
                                                                   Financial Condition and Results of Operations;
                                                                   Business; Management; Certain Transactions; Security
                                                                   Ownership of Management and Principal Stockholders;
                                                                   Description of Capital Stock; Shares Eligible for
                                                                   Future Sale; Financial Statements
      12.  Disclosure of Commission Position on Indemnification
            for Securities Act Liabilities......................                            *
</TABLE>
 
- ------------------------
*Item  is omitted  either because  it is inapplicable  or the  answer thereto is
negative.
<PAGE>
INFORMATION   CONTAINED  HEREIN  IS  SUBJECT   TO  COMPLETION  OR  AMENDMENT.  A
REGISTRATION STATEMENT  RELATING TO  THESE SECURITIES  HAS BEEN  FILED WITH  THE
SECURITIES  AND EXCHANGE  COMMISSION. THESE SECURITIES  MAY NOT BE  SOLD NOR MAY
OFFERS TO BUY BE ACCEPTED PRIOR  TO THE TIME THE REGISTRATION STATEMENT  BECOMES
EFFECTIVE.  THIS  PROSPECTUS  SHALL  NOT  CONSTITUTE AN  OFFER  TO  SELL  OR THE
SOLICITATION OF AN OFFER TO BUY NOR SHALL THERE BE ANY SALE OF THESE  SECURITIES
IN  ANY STATE IN WHICH SUCH OFFER,  SOLICITATION OR SALE WOULD BE UNLAWFUL PRIOR
TO REGISTRATION OR QUALIFICATION UNDER THE SECURITIES LAWS OF ANY SUCH STATE.
<PAGE>
                   SUBJECT TO COMPLETION, DATED MAY 10, 1996
 
                                2,800,000 SHARES
 
                                     [LOGO]
 
                                  COMMON STOCK
 
    ALL OF THE 2,800,000 SHARES OF COMMON  STOCK, PAR VALUE $.01 PER SHARE  (THE
"COMMON  STOCK"), OFFERED HEREBY (THE "OFFERING") ARE BEING SOLD BY UROCOR, INC.
("UROCOR" OR THE  "COMPANY"). PRIOR TO  THE OFFERING, THERE  HAS BEEN NO  PUBLIC
MARKET FOR THE COMMON STOCK. IT CURRENTLY IS ANTICIPATED THAT THE INITIAL PUBLIC
OFFERING  PRICE WILL BE  BETWEEN $8.00 AND $10.00  PER SHARE. SEE "UNDERWRITING"
FOR FACTORS TO BE CONSIDERED IN  DETERMINING THE INITIAL PUBLIC OFFERING  PRICE.
THE  COMMON STOCK HAS  BEEN APPROVED FOR  LISTING ON THE  NASDAQ NATIONAL MARKET
UNDER THE SYMBOL "UCOR".
 
                              -------------------
 
    AN INVESTMENT IN THE SHARES OF  COMMON STOCK OFFERED HEREBY INVOLVES A  HIGH
DEGREE  OF RISK.  SEE "RISK  FACTORS" BEGINNING  ON PAGE  5 FOR  A DISCUSSION OF
CERTAIN FACTORS  THAT SHOULD  BE  CONSIDERED BY  PROSPECTIVE PURCHASERS  OF  THE
COMMON STOCK.
 
                               -----------------
 
THESE  SECURITIES HAVE NOT  BEEN APPROVED OR DISAPPROVED  BY THE SECURITIES AND
 EXCHANGE  COMMISSION  OR  ANY  STATE  SECURITIES  COMMISSION  NOR  HAS   THE
   SECURITIES  AND EXCHANGE  COMMISSION OR ANY  STATE SECURITIES COMMISSION
     PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.  ANY
      REPRESENTATION    TO   THE   CONTRARY   IS   A   CRIMINAL   OFFENSE.
<TABLE>
<S>                                        <C>              <C>              <C>
- --------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------
 
<CAPTION>
                                                PRICE        UNDERWRITING      PROCEEDS TO
                                              TO PUBLIC      DISCOUNT (1)      COMPANY (2)
<S>                                        <C>              <C>              <C>
- --------------------------------------------------------------------------------------------
PER SHARE................................         $                $                $
TOTAL (3)................................         $                $                $
- --------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------
</TABLE>
 
(1)  SEE  "UNDERWRITING"  FOR  INFORMATION  CONCERNING  INDEMNIFICATION  OF  THE
    UNDERWRITERS AND OTHER MATTERS.
 
(2) BEFORE DEDUCTING EXPENSES PAYABLE BY THE COMPANY, ESTIMATED AT $600,000.
 
(3)  THE COMPANY HAS GRANTED THE UNDERWRITERS  A 30-DAY OPTION TO PURCHASE UP TO
    420,000 ADDITIONAL SHARES OF COMMON  STOCK SOLELY TO COVER  OVER-ALLOTMENTS,
    IF ANY. IF THE UNDERWRITERS EXERCISE THIS OPTION IN FULL, THE TOTAL PRICE TO
    PUBLIC,  UNDERWRITING DISCOUNT AND  PROCEEDS TO COMPANY  WILL BE $         ,
    $       AND $       , RESPECTIVELY. SEE "UNDERWRITING".
 
    THE SHARES OF  COMMON STOCK OFFERED  BY THIS PROSPECTUS  ARE OFFERED BY  THE
SEVERAL UNDERWRITERS NAMED HEREIN, SUBJECT TO RECEIPT AND ACCEPTANCE BY THEM, TO
PRIOR  SALE AND TO THEIR  RIGHT TO REJECT ANY  ORDER IN WHOLE OR  IN PART AND TO
WITHDRAW, CANCEL  OR  MODIFY THE  OFFER  WITHOUT  NOTICE. IT  IS  EXPECTED  THAT
DELIVERY  OF  THE CERTIFICATES  REPRESENTING SUCH  SHARES  WILL BE  MADE AGAINST
PAYMENT THEREFOR AT THE OFFICE OF MONTGOMERY SECURITIES ON OR ABOUT            ,
1996.
 
                              -------------------
 
MONTGOMERY SECURITIES                                     VOLPE, WELTY & COMPANY
 
                                          , 1996.
<PAGE>
                                     UROCOR
 
Urology is a medical specialty focused on prostate and bladder cancer, kidney
stones and other complex diseases or conditions. Urologists typically manage
their patient's total care, serving as diagnostician, surgeon and oncologist.
UroCor's goal is to complement its broad range of diagnostic services with
theraputic products and information systems to serve urologists throughout the
entire disease cycle.
 
               A SYSTEMATIC APPROACH TO TOTAL DISEASE MANAGEMENT
 
                              URODIAGNOSTICS GROUP
      -Urology-specific technical sales force and managed care specialists
  -Comprehensive detection, diagnostic, prognostic and monitoring capabilities
  -Advanced case reporting integrating uropathology, patient demographics and
                                clinical trends
 
<TABLE>
<S>                                            <C>
            UROTHERAPEUTICS GROUP                           DISEASE MANAGEMENT
      -License, acquire and distribute                      INFORMATION SYSTEMS
        urology therapeutic products                 -Implementing on-line network for
     -Inventory and logistics management               real-time communication flow
     along with reimbursement assistance        -Expanding disease pathway models, practice
      -Oncology-directed consultation,            guidelines and decision support systems
       databases and outcome tracking          -Databases of patient demographics, clinical
                                                                 findings
                                                        and archived specimen banks
</TABLE>
 
                               UROSCIENCES GROUP
              -Focus on technology solutions to clinical dilemmas
        -Internal development of new diagnostic and information products
 -Active collaborations with leading academic and medical research institutions
 
DESCRIPTION OF ARTWORK:
 
    The  background of the entire page is  a body of water. Underneath the first
paragraph are five balls,  arranged from left  to right, over  each of which  is
centered  a word (Detection, Diagnosis,  Prognosis, Therapy and Monitoring, from
left to right). Between each  of the balls is a  small triangle, pointed to  the
right.  Underneath the balls is a box,  which contains the caption "A Systematic
Approach to Total Disease Management". Arrows from this caption are directed  to
each of the balls. Also in the box, in clockwise order, is a description of each
of the UroDiagnostics Group, Disease Management Information Systems, UroSciences
Group and UroTherapeutics Group. Arrows pointing in both directions link each of
such descriptions.
 
    IN  CONNECTION WITH THIS OFFERING, THE UNDERWRITERS MAY OVER-ALLOT OR EFFECT
TRANSACTIONS THAT STABILIZE OR MAINTAIN THE MARKET PRICE OF THE COMMON STOCK  OF
THE  COMPANY AT  A LEVEL ABOVE  THAT WHICH  MIGHT OTHERWISE PREVAIL  IN THE OPEN
MARKET. SUCH TRANSACTIONS MAY BE EFFECTED ON THE NASDAQ NATIONAL MARKET, IN  THE
OVER-THE-COUNTER  MARKET OR  OTHERWISE. SUCH  STABILIZING, IF  COMMENCED, MAY BE
DISCONTINUED AT ANY TIME.
 
                                       2
<PAGE>
                               PROSPECTUS SUMMARY
 
    THE  FOLLOWING SUMMARY  IS QUALIFIED  IN ITS  ENTIRETY BY  THE MORE DETAILED
INFORMATION, INCLUDING  THE FINANCIAL  STATEMENTS AND  NOTES THERETO,  APPEARING
ELSEWHERE  IN THIS PROSPECTUS. UNLESS OTHERWISE NOTED, THE INFORMATION CONTAINED
IN THIS PROSPECTUS ASSUMES (I)  NO EXERCISE OF THE UNDERWRITERS'  OVER-ALLOTMENT
OPTION  AND  (II) THE  AUTOMATIC  CONVERSION OF  ALL  OUTSTANDING SHARES  OF THE
COMPANY'S PREFERRED STOCK, CLASS A STOCK AND CLASS B STOCK INTO SHARES OF COMMON
STOCK IMMEDIATELY PRIOR TO THE CLOSING OF THE OFFERING.
 
                                  THE COMPANY
 
    UroCor provides  a  broad range  of  diagnostic services  for  the  clinical
management  of certain urological cancers and diseases. The Company's goal is to
complement its  diagnostic services  with therapeutic  products and  information
systems  in order to  become the leading disease  management company serving the
urology market. Through its  four business groups, UroDiagnostics,  UroSciences,
UroTherapeutics  and  Disease  Management Information  Systems,  the  Company is
developing an  integrated disease  management  approach to  serve the  needs  of
urologists  and managed  care organizations  for the  diagnostic, prognostic and
therapeutic care  of patients  throughout a  disease cycle.  The  UroDiagnostics
Group  provides diagnostic  services to  over 1,400  urologists nationwide. This
group provides  comprehensive diagnostic  services  to detect  major  urological
diseases,  predict prognosis of  the patient's condition,  monitor the patient's
therapy and identify recurrence of the disease. The UroSciences Group's goal  is
to  become a  leader in the  development and application  of advanced diagnostic
technologies and  information resources  for managing  urological diseases.  The
UroTherapeutics  Group was  established to  acquire rights  to sell  through the
Company's existing sales force urological pharmaceutical products for use in the
urologist's office. The Disease Management Information Systems group is designed
to provide  urologists  and  managed  care  organizations  with  access  to  the
Company's proprietary urological disease database, disease management models and
practice  management guidelines in order to  improve the diagnosis and treatment
of patients.
 
    UroCor serves the segment of the United States urology market consisting  of
over 7,500 office-based urologists, including those affiliated with managed care
organizations.  These  urologists diagnose  and  treat prostate  cancer, bladder
cancer,  kidney  stone  disease  and  other  complex  urological  diseases.   An
independent  survey estimated that  in 1993 there  were approximately 15 million
urology patient  visits  in  the  United States.  The  American  Cancer  Society
estimates that approximately 300,000 new cases of prostate cancer and 52,000 new
cases of bladder cancer will be diagnosed in 1996, resulting in medical costs in
excess  of  $5.0  billion.  The  Company believes  that  the  urology  market is
particularly well-suited for an  integrated disease management approach  because
of the distinctive characteristics of urological diseases and the multiple roles
of  the urologist. Urological diseases typically require extensive and prolonged
diagnosis, prognosis and monitoring throughout the  course of the disease. As  a
result,  unlike  most other  medical specialties,  the urologist  often fulfills
almost all  patient  care  needs  by acting  as  diagnostician,  oncologist  and
surgeon.  UroCor believes that  it is the  first company focusing  solely on the
urology market to offer comprehensive products and services necessary to  manage
urological diseases.
 
    To  achieve its goal  of becoming the leading  disease management company in
the urology  market, the  Company is  employing these  strategies: (i)  increase
market  penetration  of office-based  urologists,  (ii) expand  use  of existing
product lines, (iii) expand  total product offering  and (iv) strengthen  market
ties  with on-line systems. To achieve increased market penetration and expanded
product use,  the  Company  has  developed  a  direct  sales  force  focused  on
urologists'  offices and managed care organizations. To expand its total product
offering, the Company intends to develop and license technologies and  products.
In  December  1994, the  Company licensed  exclusive United  States distribution
rights from IAF BioVac,  Inc., a subsidiary of  BioChem Pharma, Inc.  ("BioVac")
for a strain of BACILLUS Calmette Guerin ("BCG"), a therapeutic product to treat
certain  types of bladder cancer for  which BioVac currently is seeking approval
from the United States  Food and Drug Administration  (the "FDA") for  marketing
approval.  To strengthen its  ties with urologists, the  Company is developing a
urology-focused, secure wide area network  that will allow urologists access  to
patient  diagnostic  results  as  well  as  the  Company's  proprietary  disease
management models.
 
                                       3
<PAGE>
                                  THE OFFERING
 
<TABLE>
<S>                                                 <C>
Common Stock offered by the Company...............  2,800,000 shares
Common Stock to be outstanding after the
 Offering.........................................  9,365,248 shares(1)
Use of proceeds...................................  Development of new products, expansion
                                                    of business lines, certain capital
                                                    expenditures and working capital and
                                                    other general corporate purposes
Proposed Nasdaq National Market symbol............  UCOR
</TABLE>
 
- ------------------------
(1) Excludes  1,487,904  shares  of  Common  Stock  issuable  upon  exercise  of
    outstanding options and warrants.
 
                             SUMMARY FINANCIAL DATA
                     (IN THOUSANDS, EXCEPT PER SHARE DATA)
 
<TABLE>
<CAPTION>
                                                                                                     THREE MONTHS ENDED
                                                            YEAR ENDED DECEMBER 31,                      MARCH 31,
                                             -----------------------------------------------------  --------------------
                                               1991       1992       1993       1994       1995       1995       1996
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
<S>                                          <C>        <C>        <C>        <C>        <C>        <C>        <C>
STATEMENT OF OPERATIONS DATA:
Revenue....................................  $   2,145  $   4,813  $   9,348  $  14,531  $  19,758  $   4,619  $   5,908
Operating expenses:
  Direct cost of services and products.....      1,161      2,019      3,893      5,891      7,354      1,658      2,138
  Selling, general and administrative
   expenses................................      2,127      3,796      6,308      8,765      9,423      2,255      2,862
  Research and development.................        416        552      1,252      1,969      2,267        558        644
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
    Total operating expenses...............      3,704      6,367     11,453     16,625     19,044      4,471      5,644
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
  Income (loss) from operations............     (1,559)    (1,554)    (2,105)    (2,094)       714        148        264
Other income (expense).....................         93         42        (63)      (203)      (181)       (56)       (33)
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
Net income (loss)..........................  $  (1,466) $  (1,512) $  (2,168) $  (2,297) $     533  $      92  $     231
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
Pro forma net income (loss) per share(1)...  $    (.61) $    (.37) $    (.41) $    (.38) $     .07  $     .01  $     .03
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
Shares used in computing pro forma net
 income (loss) per share(1)................      2,396      4,093      5,233      6,104      7,296      6,588      7,523
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
                                             ---------  ---------  ---------  ---------  ---------  ---------  ---------
</TABLE>
 
<TABLE>
<CAPTION>
                                                                                              MARCH 31, 1996
                                                                                        --------------------------
                                                                                          ACTUAL    AS ADJUSTED(2)
                                                                                        ----------  --------------
<S>                                                                                     <C>         <C>
BALANCE SHEET DATA:
Cash and cash equivalents.............................................................  $    1,301    $   24,137
Working capital.......................................................................       5,086        27,922
Total assets..........................................................................      12,034        34,870
Long-term debt........................................................................         950           950
Accumulated deficit...................................................................     (14,124)      (14,124)
Total stockholders' equity............................................................       8,702        31,538
</TABLE>
 
- --------------------------
 
(1) Computed on the basis described in Note 2 to the Financial Statements.
 
(2)  Adjusted to reflect  the sale of  2,800,000 shares of  Common Stock offered
    hereby at an assumed  initial public offering price  of $9.00 per share  and
    the  receipt of the estimated net  proceeds therefrom. See "Use of Proceeds"
    and "Capitalization".
 
                                       4
<PAGE>
                                  RISK FACTORS
 
    AN  INVESTMENT IN THE COMMON STOCK OFFERED  HEREBY INVOLVES A HIGH DEGREE OF
RISK. THE FOLLOWING FACTORS  SHOULD BE CONSIDERED  CAREFULLY, TOGETHER WITH  THE
INFORMATION  PROVIDED ELSEWHERE IN THIS  PROSPECTUS, IN EVALUATING AN INVESTMENT
IN THE SHARES OF COMMON STOCK OFFERED HEREBY.
 
REORGANIZATION; HISTORY OF LOSSES; LIMITED HISTORY OF PROFITABLE OPERATIONS
 
    As a result  of certain litigation  and the Company's  inability to  achieve
commercial  viability, in  1990 the  Company filed  a reorganization  plan under
Chapter 11  of the  United States  Bankruptcy Code  which was  confirmed by  the
bankruptcy  court  in  1991.  In  the  reorganization,  creditors'  claims  were
discharged, certain litigation claims were settled and the rights and  interests
of the Company's equity holders were terminated. See "The Company".
 
    The Company recorded net losses of approximately $1.5 million, $1.5 million,
$2.2  million and $2.3 million for the years ended December 31, 1991, 1992, 1993
and 1994, respectively. While  the Company reported net  income of $0.5  million
for  the year ended  December 31, 1995, and  net income of  $0.2 million for the
three months ended  March 31,  1996, the Company  may experience  losses in  the
future  until  such  time,  if ever,  as  its  operations  consistently generate
sufficient revenue to cover  its costs. At  March 31, 1996,  the Company had  an
accumulated deficit of $14.1 million. There can be no assurance that the Company
will  ever be consistently profitable. See "Management's Discussion and Analysis
of Financial Condition and Results of Operations".
 
NEED FOR FUTURE FUNDING; UNCERTAINTY OF ACCESS TO CAPITAL
 
    To remain  competitive,  the  Company  must  continue  to  make  significant
expenditures  for  expansion  of  its  operations,  including  expenditures  for
diagnostic product development, acquisitions of therapeutic products,  marketing
resources  and  information  systems capabilities.  In  addition,  the Company's
growth since 1991 has required, and any future growth will require,  significant
amounts  of working  capital. The  Company believes  that the  proceeds from the
Offering, together  with  existing cash  balances,  cash flow  from  operations,
capital  leases and an existing  bank credit facility, will  be adequate to fund
its anticipated capital expenditures and working  capital needs for the next  24
months.  After that 24-month period, however, the Company may require additional
equity or debt financing to meet its working capital requirements. There can  be
no  assurance  that  additional  capital  will not  be  required  sooner  or, if
required, that it will be available on  a timely basis or on terms  satisfactory
to  the  Company. The  inability of  the Company  to obtain  adequate additional
financing on reasonable terms when needed  would have a material adverse  effect
on  the Company's financial  condition and results  of operations. If additional
funds are  raised through  the  issuance of  equity securities,  the  percentage
ownership of then current stockholders of the Company would be reduced. Further,
such  equity securities  may have  rights, preferences  or privileges  senior to
those  of  the   Common  Stock.   See  "Use   of  Proceeds",   "Capitalization",
"Management's  Discussion  and Analysis  of Financial  Condition and  Results of
Operations" and "Description of Capital Stock".
 
UNCERTAINTIES RELATED TO THIRD-PARTY REIMBURSEMENT; POTENTIAL HEALTH CARE REFORM
 
    The Company typically bills governmental programs such as Medicare and other
third-party payors such  as private  insurance and  managed care  plans for  its
products  and  services. Such  third-party  payors are  increasingly negotiating
prices with the goal of lowering reimbursement rates. The Company expects  these
pricing  pressures,  combined with  the introduction  of new  diagnostic product
lines with  lower average  prices per  specimen, to  cause reduced  revenue  per
specimen in the future.
 
    In  1993, 1994, 1995 and the first  three months of 1996, approximately 56%,
58%, 58%  and 53%,  respectively,  of the  Company's  revenue was  derived  from
services  performed principally for  beneficiaries of the  Medicare program. For
many of  the services  performed for  Medicare beneficiaries,  the Company  must
accept reimbursement from Medicare as payment in full, subject to applicable co-
payments and deductibles. Reimbursement rates have been established for most but
not  all of the services performed by  the Company. The Company, however, cannot
collect from Medicare or other third-party payors for services that those payors
have not approved for reimbursement. Approval of
 
                                       5
<PAGE>
such services by Medicare or other federal agencies does not ensure approval  by
other  third-party payors. A formal  determination for reimbursement approval is
made, however, with respect to  relatively few new procedures. Most  third-party
payors,  including Medicare,  do not  cover services  that they  determine to be
experimental, investigational  or otherwise  not  reasonable and  necessary  for
diagnosis  or  treatment.  There can  be  no  assurance that  the  Company's new
Free/Total PSA product or any other products under development will be  approved
for  reimbursement by  Medicare or other  third-party payors.  Medicare also may
audit and  review its  prior payments  to the  Company, and  may determine  that
certain of those payments must be refunded. It is also possible that third-party
payors may cease to pay for one or more of the Company's services that currently
are  reimbursed by them. Significant disapprovals by various carriers, including
Medicare,  private  insurance  and  managed   care,  reductions  or  delays   in
establishing  reimbursement  rates  and  insurance  carrier  limitations  on the
coverage of the Company's services could  have a material adverse effect on  the
Company's  future revenue. While  the Company is  certified for participation in
the Medicare program, any loss of  such certification, whether arising from  any
action by an agency of the federal government or any other regulatory authority,
or  any  related  civil or  administrative  proceedings, would  have  a material
adverse effect on the Company's  financial condition and results of  operations.
See "Business -- Third Party Reimbursement".
 
    In  addition, since  1994, the  Company's Medicare  intermediary and certain
other third-party payors have increased the amount of time between their receipt
of claims for reimbursement and payment to  the Company. At March 31, 1996,  the
Company's  average  number of  days sales  in  receivables was  approximately 74
compared to 49 at December 31, 1994. Such delays in payments to the Company have
resulted in the Company's accounts receivable increasing at a rate greater  than
the  revenue growth rate  and, therefore, have affected  the Company's cash flow
from operations. There can  be no assurance that  these payors will not  further
modify  their payment practices,  which could have a  material adverse effect on
the Company's financial condition and  results of operations. See  "Management's
Discussion and Analysis of Financial Condition and Results of Operations".
 
    From  time to time  the public and the  federal government focus significant
attention on reforming the health care  system in the United States. Any  future
changes  in Medicare and other third-party  payor reimbursement which may result
from health care reform  or deficit reduction  legislation will likely  continue
the  downward pressure on  prices. Because of  the uncertainties surrounding the
nature, timing and extent of any such reform initiatives, the Company is  unable
to  predict the  effects of any  such changes  on the Company.  See "Business --
Government Regulation".
 
DEPENDENCE ON CERTAIN PRODUCT LINES
 
    A significant portion of the Company's revenue has been, and is expected  to
continue  to  be,  dependent upon  the  Company's prostate  tissue  analysis and
bladder cellular analysis product lines.  The Company's revenue attributable  to
prostate  tissue analysis accounted  for approximately 29%, 48%,  54% and 54% of
revenues in 1993, 1994, 1995 and  the first three months of 1996,  respectively.
The  Company's revenue attributable  to bladder cellular  analysis accounted for
approximately 53%, 36%, 30% and 26% of revenue in 1993, 1994, 1995 and the first
three months of 1996, respectively. Any negative event related to these  product
lines,  such  as  increased  competition,  pricing  pressures  and  clinical  or
technological obsolescence  would have  a  material and  adverse effect  on  the
Company's  financial  condition  and  results of  operations.  See  "Business --
Business Lines -- UroDiagnostics Group -- Products".
 
NO ASSURANCE OF SUCCESSFUL ACQUISITION OF DISTRIBUTION RIGHTS FOR THERAPEUTIC
PRODUCTS
 
    Through its UroTherapeutics Group, the  Company is developing a  therapeutic
products  distribution business. To date,  the Company has acquired distribution
rights for only  one therapeutic  product. There can  be no  assurance that  the
Company  will be successful in negotiating  any additional distribution or other
agreements related to therapeutic products in the future. The Company has  never
marketed  or distributed any therapeutic products. If its efforts in this regard
are unsuccessful,  it could  have a  material adverse  effect on  the  Company's
financial  condition and results of operations. The manufacturers of therapeutic
products are responsible for  compliance with FDA  regulations relating to  such
 
                                       6
<PAGE>
products;  thus  the  Company is  and  will  be dependent  on  others  to obtain
marketing approval  for  any  therapeutic  products  for  which  it  may  obtain
distribution  rights. The Company also will rely on third parties to manufacture
products in  a timely  fashion.  Product unavailability  could have  a  material
adverse effect on future business performance.
 
    In December 1994, the Company entered into a distribution agreement with IAF
BioVac  Inc. ("BioVac"), a subsidiary of BioChem Pharma, Inc., for a BCG product
for  use  in  treating  certain  types  of  bladder  cancer.  Pursuant  to   the
distribution  agreement, BioVac is responsible  for obtaining approvals from the
FDA for marketing the BCG product in the United States. UroCor may not  commence
selling  the product  in the  United States until  BioVac has  obtained such FDA
approval. In April  1995, BioVac filed  its initial applications  with the  FDA.
BioVac  has informed the Company that in a  letter dated April 18, 1996, the FDA
advised BioVac that its application is not approvable at this time and that  the
FDA  requested additional  data regarding  certain aspects  of manufacturing and
testing of the product. BioVac has advised the Company that notwithstanding  the
receipt  of the non-approvable letter  from the FDA, it  believes it can satisfy
FDA requirements and procure  approval for marketing the  product in the  United
States.  There can be no assurance, however,  that approval will be obtained. In
addition, if FDA approval  is obtained, to  maintain its exclusive  distribution
rights  under  the  agreement the  Company  must satisfy  certain  minimum sales
requirements. Although the Company has no reason to believe it will be unable to
satisfy those  requirements, no  assurance  can be  given  in that  regard.  See
"Business -- Business Lines -- UroTherapeutics Group".
 
    The Company's success in the distribution of therapeutic products is subject
to risks, including the possibilities that the proposed products fail to receive
necessary  regulatory approvals,  that the  proposed products  or procedures are
uneconomical to market  or do not  achieve broad market  acceptance, that  third
parties  hold proprietary rights  that preclude the  Company from marketing them
and that third parties market a superior or equivalent product. UroCor is unable
to predict whether the distribution rights it has obtained for the proposed  BCG
product  or any distribution rights  it may obtain in  the future will result in
any commercially  viable products.  Further,  due to  the extended  testing  and
regulatory  review process required  before marketing approval  can be obtained,
the development  period  for  any such  products  is  long and  the  timing  for
commercialization is uncertain.
 
UNCERTAINTY RELATED TO GOVERNMENT REGULATION
 
    The  Company's diagnostic laboratory operations currently are required to be
certified or licensed under the  federal Clinical Laboratory Improvement Act  of
1967,  as  amended in  1988  ("CLIA"), the  Medicare  and Medicaid  programs and
various state and local laws. In some instances, the Company is also subject  to
licensing  or regulation under  federal and state laws  relating to the handling
and  disposal  of  medical  specimens,   infectious  and  hazardous  waste   and
radioactive  materials,  as  well as  to  the  safety and  health  of laboratory
employees. The  sanctions  for failure  to  comply with  these  regulations  may
include  denial of the right to conduct business, significant fines and criminal
penalties. The loss of  a license, imposition  of a fine or  an increase in  the
complexity or substantive requirements of such federal, state and local laws and
regulations  could have  a material  adverse effect  on the  Company's financial
condition and results of operations. See "Business -- Government Regulation" and
"Business -- Environmental Matters".
 
    The Company's diagnostic laboratory  operations currently are not  regulated
by the FDA. While the FDA now indicates that it does not plan to regulate assays
developed  by laboratories  for in-house  use, the FDA  has in  the past drafted
guidelines for regulation of such assays. If in the future the FDA were to issue
guidelines for  the clinical  laboratory market  sector, such  guidelines  might
require the Company to meet certain FDA medical device approval requirements for
the  Company's  in-house assays.  Such  regulations, if  enacted  in a  way that
affects the Company, would increase the cost of development and approval of  new
products,  slow  their introduction  to  the market  and  could have  a material
adverse effect on the Company's  financial condition and results of  operations.
See "Business -- Government Regulation".
 
                                       7
<PAGE>
    The  FDA  currently regulates  a number  of the  products which  the Company
purchases  from  third  parties  for   use  in  its  diagnostic  services.   The
manufacturers   of  such  products  are  responsible  for  compliance  with  FDA
regulations relating to such products. There can be no assurance, however,  that
action by the manufacturers or by the FDA would not impair the Company's ability
to obtain and offer certain services. The unavailability of certain services and
materials  used  in the  Company's diagnostics  business  would have  a material
adverse effect on the Company's financial condition and results of operations.
 
    Although the Company's existing  and proposed information services  products
currently  are not subject to regulation by  the FDA, the FDA could determine in
the future that the predictive applications  of these products are deemed to  be
medical  devices subject  to FDA  regulation. In  that event,  the Company could
experience delays  in developing  and marketing  new services  and increases  in
research and development costs.
 
    As  a provider of  health care related  services, the Company  is subject to
extensive and frequently changing federal, state and local laws and  regulations
governing  licensure,  billing, financial  relationships, referrals,  conduct of
operations, purchase of existing businesses, cost-containment, direct employment
of licensed  professionals by  business corporations  and other  aspects of  the
Company's  business  relationships. The  Company  cannot predict  the  timing or
impact of any  changes in such  laws and  regulations, and no  assurance can  be
given  that any  such changes  will not  have a  material adverse  effect on the
Company's financial  condition  and  results of  operations.  See  "Business  --
Government Regulation".
 
UNCERTAINTIES RELATED TO MANAGED CARE
 
    Managed care organizations are gaining increasing control over the access to
health  care for an increasing number of patients with urological diseases. Many
of these organizations  seek to  obtain health care  service provider  contracts
with  a minimum number of large, full-service vendors for all required services,
and to obtain from such vendors large discounts or capitated contracts in  which
all  products or  services for  all their  enrolled patients  are paid  for by a
contractual monthly  fee  based  on  the number  of  patients  enrolled  in  the
organization.  The  majority  of the  Company's  managed care  contracts  may be
canceled by the managed care organization upon  30 to 60 days notice. There  can
be no assurance that the Company will be able to maintain its existing contracts
with  managed care organizations  or that it  will be able  to obtain additional
contracts with such organizations in the future which could preclude the Company
from serving large  groups of  physicians in  certain markets.  The Company  has
experienced increased pricing pressure from managed care organizations, and such
pressure  is expected to continue.  There can be no  assurance that such pricing
pressure and contract restrictions  will not have a  material adverse effect  on
the  Company's financial condition  and results of  operations. See "Business --
Third-Party Reimbursement".
 
NO ASSURANCE OF ACCESS TO AND DELIVERY OF NEW DIAGNOSTIC TECHNOLOGY
 
    The markets  for  the Company's  diagnostic  products are  characterized  by
rapidly  changing technology, frequent new product introductions and enhancement
and, therefore, rapid product obsolescence. The Company's future success will be
highly dependent upon its ability to continue to develop new diagnostic products
or services while  enhancing current  capabilities in  order to  keep pace  with
technological  advancements  in  urology. There  can  be no  assurance  that the
Company will be able to identify new products, trends or opportunities,  develop
and  bring  to market  new products,  respond  effectively to  new technological
changes or product announcements by others, develop or obtain access to advanced
materials or receive commercial acceptance for its products. In addition,  there
can  be no assurance that products or  technologies developed by others will not
render the Company's products or technologies non-competitive or obsolete.
 
    The Company's  principal  sources of  such  technology are  (i)  test  kits,
reagents  and  other products  purchased  from manufacturers,  (ii) intellectual
property, such  as  processes,  products, devices  and  software  licensed  from
academic  and research institutions,  other commercial entities  and the federal
government and (iii)  new technology  developed under  strategic alliances  with
other commercial entities
 
                                       8
<PAGE>
or  through  sponsored  or  collaborative research  programs  with  academic and
research institutes. There can be no assurance that the Company will continue to
obtain new technologies important to its business in the future. The Company may
not be able  to negotiate successfully  technology acquisition or  collaborative
arrangements  in the future. The Company may enter into such arrangements but be
unable to develop any commercially viable technologies. If the Company's  access
to and delivery of new technologies were substantially diminished, the Company's
business could be materially and adversely affected.
 
    In  March 1996, the FDA published a  proposed rule to classify or reclassify
certain reagents supplied to the Company. The impact of this proposal, if it  is
finalized,  cannot be determined  at this time.  The proposal, however, includes
requirements with which suppliers  of reagents would  need to comply,  including
the  need  to  follow  the  FDA's  Good  Manufacturing  Practices,  as  well  as
registration  and  reporting  requirements  for  suppliers.  The  proposal,   if
finalized, could therefore have an impact on the Company's cost and availability
of reagents.
 
SUBSTANTIAL COMPETITION
 
    The  industry  in  which  the  Company's  diagnostics  business  operates is
characterized by intense  competition with many  different types of  competitors
including   specialty   laboratories,   diagnostic   kit   and   instrumentation
manufacturers, local and regional pathology services, hospital laboratories  and
large general reference clinical laboratories. Many of the Company's competitors
are significantly larger and have significantly greater financial, technical and
administrative  resources  than the  Company;  many also  have  long established
relationships  with  the  Company's  current  and  prospective  customers.   See
"Business -- Competition".
 
    The  competition for the acquisition  of new diagnostic testing technologies
and therapeutic  products  is intense.  The  Company competes  with  many  other
companies  for diagnostic products and  major and other pharmaceutical companies
for therapeutic products. Many of  these companies are significantly larger  and
have significantly greater financial and other resources than the Company. There
can be no assurance that the Company will continue to be successful in acquiring
new  technologies  for use  in its  diagnostic  services business.  Although the
Company was successful in acquiring the distribution rights to the BCG  product,
the Company's first proposed therapeutic product, there can be no assurance that
it will continue to be successful in this regard. See "Business -- Competition".
 
    Competition  in  the marketing  of pharmaceutical  products is  intense. The
Company is  aware  of  two  other companies  that  already  are  distributing  a
therapeutic  product  similar  to the  Company's  proposed BCG  product.  If FDA
approval for the BCG  product is obtained,  there can be  no assurance that  the
Company  will  be  able  to  market  successfully  this  product  against  these
competitors. See "Business -- Competition".
 
    The market  for  health care  information  systems and  services  is  highly
competitive.  The  Company's  competitors include  other  providers  of outcomes
software and databases based on claims  data. Many of the Company's  competitors
and  potential  competitors have  greater  financial development,  technical and
marketing resources than  the Company, and  have substantial installed  customer
bases   in  the  health  care  industry.  The  Company  also  faces  significant
competition  from  internal  information  services  at  hospitals,  which   have
developed  their own outcomes databases. In addition, as the market for outcomes
software develops, additional competitors may  enter the market and  competition
may intensify. There can be no assurance that the Company's business will not be
materially and adversely affected by such competition. See "Business -- Business
Lines -- Disease Management Information Systems".
 
    Combinations   of  current  and  future  competitors  through  acquisitions,
mergers, alliances or marketing or distribution agreements could result in  more
intense  competition in the  future. There can  be no assurance  that current or
future competitors  will not  succeed in  developing technologies,  products  or
managed care marketing programs and capabilities that are more effective, easier
to  use or less expensive than those that  are being developed by the Company or
that would  render the  Company's technology,  products and  marketing  approach
obsolete, noncompetitive or unprofitable.
 
                                       9
<PAGE>
RISKS ASSOCIATED WITH MANAGEMENT OF GROWTH
 
    The  Company  recently  has  experienced  substantial  growth  and  expanded
significantly  its   diagnostic  services   operational  capabilities,   support
operations and research and development operations. The Company also is planning
to  offer a therapeutic  product line and information  services. This growth and
expansion has placed, and  will continue to place,  a significant strain on  the
Company's  management, production, technical, financial  and other resources. To
manage growth effectively, the Company must maintain a high level of operational
quality and efficiency, and must continue to enhance its operational,  financial
and  management systems and expand, train and manage its employee base. To date,
the Company  has experience  primarily in  managing a  diagnostics business  and
marketing  diagnostic  products.  The  Company has  no  experience  in managing,
operating or  marketing  products for  a  therapeutics or  information  services
business. There can be no assurance that the Company will be able to manage this
expansion  effectively, and any failure  to do so could  have a material adverse
effect on the Company's financial condition and results of operations.
 
POTENTIAL FLUCTUATIONS IN OPERATING RESULTS
 
    The Company's quarterly and annual operating results are affected by a  wide
variety  of factors, many of which are outside the Company's control, which have
in the past  and could in  the future materially  and adversely affect  revenue,
operating  expenses and income. These factors  include the quantities and timing
of specimens received, competitive pricing  pressures, availability and cost  of
diagnostic  supplies, changes in  the mix of  products sold, seasonality, timing
and costs of  new product  and technology introductions  by the  Company or  its
competitors,  retention and expansion of the  sales force and timing of payments
from Medicare and other third-party payors. The need for continued investment in
research and development  and expansion  of its  product lines  could limit  the
Company's  ability to reduce expenses quickly. As a result of these factors, the
Company expects  its operating  results  to continue  to fluctuate.  Results  of
operations  in any one quarter should not be considered indicative of results to
be expected for  any future period,  and fluctuations in  operating results  may
also  cause  fluctuations  in  the  market  price  for  the  Common  Stock.  See
"Management's Discussion  and Analysis  of Financial  Condition and  Results  of
Operations -- Quarterly Results of Operations".
 
UNCERTAINTY REGARDING PATENTS AND PROPRIETARY RIGHTS
 
    The  Company's  business depends  in  part upon  its  intellectual property,
including patents, copyrights, trade secrets, know-how and continuing technology
innovation. The Company licenses patents  and seeks patents when appropriate  on
inventions  concerning  new products  and improvements  as  part of  its ongoing
research, development and marketing  efforts. The Company  also intends to  seek
copyright  protection when appropriate  for any information  systems products it
may develop. There can be  no assurance that any steps  taken by the Company  to
protect  its intellectual property will be adequate to prevent misappropriation,
that any patents issued to or licensed  by the Company will not be  invalidated,
circumvented  or challenged or that the rights granted thereunder will provide a
competitive advantage. Furthermore, there can  be no assurance that others  will
not  independently  develop technologies  that are  similar  or superior  to the
Company's  technology  and  obtain  patents  or  copyrights  relating  to   such
technologies.  In  such event,  the  Company may  not  be able  to  license such
technologies on  acceptable  terms.  Although  the  Company  believes  that  its
products  and technology do not infringe  upon the proprietary rights of others,
there can be no assurance that third parties will not assert infringement claims
in the future. Moreover,  litigation may be necessary  in the future to  enforce
the  Company's patents,  copyrights and  other intellectual  property rights, to
protect the Company's trade secrets, to determine the validity and scope of  the
proprietary  rights of  others or  to defend  against claims  of infringement or
invalidity. Such litigation could result  in substantial costs and diversion  of
resources  and could have  a material adverse effect  on the Company's financial
condition and results of operations. See "Business -- Intellectual Property".
 
DEPENDENCE ON KEY PERSONNEL
 
    The Company's ability to market and deliver its products and services and to
achieve and maintain a competitive position is dependent in large part upon  the
efforts of its senior management. The loss of
 
                                       10
<PAGE>
the  services  of one  or more  members of  its senior  management could  have a
material adverse  effect on  the Company's  financial condition  and results  of
operations.  The Company's future  success also will depend  upon its ability to
attract and retain qualified management, scientific, technical and manufacturing
employees to  support  its future  growth.  Competition for  such  personnel  is
intense,  and there can be  no assurance that the  Company will be successful in
attracting or retaining such personnel. The  failure to attract and retain  such
persons  could materially adversely affect the Company's financial condition and
results of operations. See "Management".
 
POTENTIAL LIABILITIES; LIMITED INSURANCE COVERAGE
 
    Employees  of  the  Company,  like  those  of  all  companies  that  provide
diagnostic  services dealing with human blood specimens, may be exposed to risks
of infection from AIDS, hepatitis and other blood-borne diseases if  appropriate
laboratory  practices are not followed. Although no infections of this type have
been reported in the Company's history,  no assurance can be provided that  such
infections  will not occur in  the future. The Company  could also be subject to
legal actions arising out of the  misperformance of its testing services or  the
malpractice  of professional  physician services.  Any such  legal actions could
have a material adverse effect on the Company's financial condition and  results
of operations.
 
    Although the Company presently is covered by medical malpractice and general
liability  insurance, there can be no assurance that the insurance coverage will
provide sufficient funds to satisfy any judgments which could be entered against
the Company in the future  or that liability insurance  in such amounts will  be
available  or affordable in the  future. In addition, there  can be no assurance
that all of the activities encompassed within the Company's business are covered
under the Company's insurance policies. The  lack of such coverage could have  a
material  adverse effect  on the  Company's financial  condition and  results of
operations. Moreover,  although  the  Company maintains  personal  property  and
business  interruption insurance and  has taken what it  believes to be adequate
safeguards, the catastrophic loss of the Company's tissue or cell library  could
have a material adverse effect on the continued development of its database in a
manner which would not be compensated fully by insurance.
 
    The commercial sale of therapeutic products by the Company will expose it to
potential  product liability  risks that are  inherent in the  marketing of such
products for human use.  These claims might be  made directly by consumers.  The
Company  currently has no product liability  insurance, and although it plans to
obtain such insurance prior to marketing  any therapeutic product, there can  be
no  assurance that the Company will be able to obtain or maintain such insurance
on acceptable  terms  or that  such  insurance will  provide  adequate  coverage
against  potential liabilities. A product liability  claim could have a material
adverse effect on the Company's financial condition and results of operations.
 
RISKS ASSOCIATED WITH HAZARDOUS MATERIALS
 
    The Company's diagnostic  services and research  and development  activities
involve  the  controlled  use  of  hazardous  materials,  chemicals  and various
radioactive compounds. Although the Company believes that its safety  procedures
for  handling  and  disposing  of  such  materials  comply  with  the  standards
prescribed  by  state   and  federal   regulations,  the   risk  of   accidental
contamination or injury from these materials cannot be completely eliminated. In
the  event of such an accident, the Company could be held liable for any damages
that result and any  such liability could exceed  the resources of the  Company.
See "Business -- Environmental Matters".
 
IMMEDIATE AND SUBSTANTIAL DILUTION; ABSENCE OF DIVIDENDS
 
    The initial public offering price is substantially higher than the pro forma
net  tangible book  value per  share of the  Common Stock.  Purchasers of Common
Stock in  the Offering  will experience  immediate and  substantial dilution  of
$5.67  per share, assuming an initial public  offering price of $9.00 per share.
See "Dilution".
 
    The Company has  never paid cash  dividends and does  not anticipate  paying
cash  dividends on  the Common  Stock in  the foreseeable  future. See "Dividend
Policy".
 
                                       11
<PAGE>
ABSENCE OF PRIOR PUBLIC MARKET; DETERMINATION OF OFFERING PRICE; POSSIBLE
VOLATILITY OF STOCK PRICE
 
    Prior to the Offering, there has been no public market for the Common Stock.
Although the Common Stock has been  approved for listing on the Nasdaq  National
Market,  there can be no assurance that an active trading market will develop or
continue upon completion of the Offering.  The initial public offering price  of
the  Common  Stock will  be determined  by negotiations  between UroCor  and the
representatives of the  underwriters and  may not  be indicative  of the  market
price  of  the Common  Stock after  the Offering.  There has  been a  history of
significant volatility in the market prices  for shares of companies engaged  in
the  health care and biotechnology fields, and the market price of the shares of
Common Stock offered pursuant  to the Offering may  be highly volatile.  Factors
such  as fluctuations in the Company's quarterly revenues and operating results,
announcements of technological  innovations or  new analytical  services by  the
Company  and  its  competitors  and  changes  in  third-party  reimbursement and
governmental regulation may have a significant effect on the market price of the
Common Stock. For a  discussion of factors to  be considered in determining  the
initial public offering price, see "Underwriting".
 
CONTROL BY EXISTING STOCKHOLDERS; POSSIBLE ANTI-TAKEOVER EFFECTS
 
    Upon  completion of the  Offering, the Company's  existing stockholders will
own beneficially approximately 70.1% of  the Company's outstanding Common  Stock
(67.1%  if  the  Underwriters  exercise  the  over-allotment  option  in  full).
Accordingly, the  existing stockholders,  acting  as a  group,  may be  able  to
influence  the  outcome of  stockholder  votes, including  votes  concerning the
election of directors, the adoption or amendment of provisions to the  Company's
Restated   Certificate   of   Incorporation   (the   "Restated   Certificate  of
Incorporation") or Amended and Restated By-laws (the "By-laws") and the approval
of certain mergers and significant corporate transactions. These provisions  and
control  by existing stockholders  could limit the  price that certain investors
might be willing to pay  in the future for shares  of Common Stock and have  the
effect  of delaying, deferring or preventing a change in control of the Company.
See "Security Ownership of Management and Principal Stockholders".
 
    The Restated Certificate of  Incorporation and By-laws  include a number  of
provisions   that  may  have  the  effect  of  encouraging  persons  considering
unsolicited tender offers  or other unilateral  takeover proposals to  negotiate
with the Company's Board of Directors rather than pursue non-negotiated takeover
attempts.  These  provisions  include authorized  blank  check  preferred stock,
denial of cumulative voting,  limitation of the persons  who may call a  special
meeting  of  stockholders,  advance  notice  requirements  for  nominations  for
election to the  Board of  Directors and a  classified Board  of Directors.  See
"Description of Capital Stock".
 
POTENTIAL EFFECT OF SHARES ELIGIBLE FOR FUTURE SALE ON PRICE OF COMMON STOCK;
REGISTRATION RIGHTS
 
    Upon completion of the Offering, the Company will have outstanding 9,365,248
shares  of Common  Stock (9,785,248  shares if  the Underwriters' over-allotment
option is exercised in full).  The 2,800,000 shares to  be sold in the  Offering
(plus   any  additional   shares  sold   upon  exercise   of  the  Underwriters'
over-allotment option) will  be freely  tradeable in the  public market  without
restriction or further registration under the Securities Act of 1933, as amended
(the  "Securities Act"),  except for any  shares purchased by  affiliates of the
Company.
 
    The Company  and  its  executive  officers, directors  and  certain  of  the
stockholders of the Company, all of whom together beneficially own approximately
6,102,000  shares, representing  approximately 65.2%  of the  Common Stock after
giving effect to  the issuance of  the shares  of Common Stock  in the  Offering
(62.4%  if the Underwriters'  over-allotment option is  exercised in full), have
agreed that, for a period  of 180 days after the  date of this Prospectus,  they
will  not,  directly or  indirectly, offer,  sell, contract  to sell,  grant any
option to sell or  otherwise dispose of, directly  or indirectly, any shares  of
Common  Stock or securities convertible into  or exchangeable for, or any rights
to purchase  or acquire,  Common Stock,  without the  prior written  consent  of
Montgomery Securities. Montgomery Securities, in its sole discretion, and at any
time without notice, may release all or any portion of the securities subject to
the 180-day lock-up agreement.
 
                                       12
<PAGE>
    Of the 6,565,248 shares of Common Stock held by existing stockholders of the
Company,  (i)  approximately 214,000  will be  eligible for  sale in  the public
market immediately following the Offering  and (ii) an additional  approximately
5,506,000  shares will  be eligible  for sale  in the  public market immediately
following the  expiration  of the  180-day  lock-up described  above,  of  which
approximately   1,539,000  shares  are  subject  to  certain  volume  and  other
restrictions under Rule 144.
 
    As of  the date  of this  Prospectus, options  and warrants  to purchase  an
aggregate  of  1,487,904  shares  of  Common  Stock  are  outstanding  of  which
approximately 920,000 shares underlying such options and warrants are subject to
the 180-day lock-up agreement.
 
    Certain of  the Company's  existing stockholders  have certain  rights  with
respect  to  the  registration  under  the Securities  Act  of  an  aggregate of
5,886,601 shares of Common  Stock (the "Registrable  Shares"). In general,  such
stockholders  may demand on  up to two  occasions that the  Company register the
sale of their shares of Common Stock. Each holder of Registrable Shares also has
piggy-back registration rights, subject to certain limitations, in the event the
Company proposes to register the sale of any shares of Common Stock or any other
securities of  the  Company for  its  own account  or  for the  account  of  its
stockholders. The Company is obligated to bear all of the expenses in connection
with the registration of the Registrable Shares, except underwriting commissions
and  discounts. Any sales of  Registrable Shares will be  subject to the 180-day
lock-up described under "Shares Eligible for Future Sale" and "Underwriting".
 
    Prior to the Offering, there has been no public market for the Common Stock,
and no prediction can be made as to the effect, if any, that the sale of  shares
or  the availability  of shares for  sale will have  on the market  price of the
Common Stock prevailing from  time to time.  Nevertheless, sales of  substantial
amounts  of  the  Common  Stock  in the  public  market  could  adversely affect
prevailing market prices and the ability of the Company to raise equity  capital
in the future. See "Shares Eligible for Future Sale" and "Underwriting".
 
                                       13
<PAGE>
                                  THE COMPANY
 
    The   Company   was  incorporated   in  Texas   in   1985  under   the  name
CytoDiagnostics, Inc. The  Company was  reincorporated in Delaware  in 1988.  In
1994,  the  Company changed  its name  to UroCor,  Inc. The  Company's executive
offices and  operations are  located  at 800  Research Parkway,  Oklahoma  City,
Oklahoma 73104, and its telephone number is 405/290-4000.
 
    As  a result  of certain litigation  and the Company's  inability to achieve
commercial viability, in November 1990, the Company filed a reorganization  plan
under  Chapter 11 of the United States Bankruptcy Code that was confirmed by the
bankruptcy court in March  1991. In the  reorganization, creditors' claims  were
discharged,  certain litigation claims were settled and the rights and interests
of the Company's equity holders were terminated. In late 1989, the Company began
recruiting new senior management and refocused  its strategy to provide a  broad
range  of  diagnostic products  and services  intended  to improve  the clinical
management of  certain major  urological  cancers and  complex diseases  and  to
develop an integrated disease management company serving the urology market.
 
                                USE OF PROCEEDS
 
    The  net proceeds to  the Company from  the sale of  the 2,800,000 shares of
Common Stock offered by the Company pursuant to the Offering are estimated to be
approximately $22.8 million ($26.4 million, if the Underwriters'  over-allotment
option  is exercised in full), based on an assumed initial public offering price
of $9.00 per share and after  deducting the estimated underwriting discount  and
offering expenses payable by the Company.
 
    The  Company expects that approximately $19.0 million of the net proceeds of
the Offering  will be  used as  follows: approximately  $3 million  to fund  the
development  and  expansion of  its  diagnostic product  line,  approximately $3
million for the development of its urological disease data bases,  approximately
$6  million  for development  of a  therapeutic  product line,  approximately $4
million for the development and  expansion of information products and  services
and   approximately  $3  million  for   capital  expenditures  relating  to  the
development and expansion of clinical  and research laboratory capabilities  and
laboratory  information systems. The Company  believes that the amounts actually
expended for the development of a theraputic product line may vary significantly
depending primarily on the availability of appropriate products, the ability  of
the  Company  to  acquire  rights  to  such  products  and  the  availability of
appropriate joint venture or other collaboration opportunities pursuant to which
the Company may acquire rights to such products without the expenditure of cash.
The Company expects that any  portion of the $6.0  million of proceeds not  used
for  this purpose will be expended in  approximately equal amounts for the other
four anticipated principal uses of proceeds.
 
    The Company intends  to use the  remainder of the  net proceeds for  working
capital  and general corporate purposes.  The Company may also  use a portion of
such net  proceeds  to  acquire  or invest  in  businesses  with  diagnostic  or
information  products and  technologies that are  complementary to  those of the
Company, although no specific acquisitions or investments are planned as of  the
date  of this Prospectus, and no portion of such net proceeds has been allocated
for any particular  acquisition or  investment. Pending such  uses, the  Company
intends  to invest the aggregate net  proceeds from this Offering in short-term,
investment-grade, interest-bearing securities.
 
    The Company estimates that its existing capital resources, the net  proceeds
from  the  Offering  and  interest thereon,  together  with  bank  and equipment
financing, will be sufficient to fund  the Company's requirements for 24  months
following the closing of the Offering. See "Management's Discussion and Analysis
of  Financial  Condition  and Results  of  Operations --  Liquidity  and Capital
Resources".
 
                                DIVIDEND POLICY
 
    UroCor has never declared  or paid any cash  dividends on its Common  Stock.
The  Company intends to  retain any future  earnings for the  development of its
business. Accordingly, the Company does not anticipate paying cash dividends  on
the  Common Stock in the foreseeable  future. The Company's existing bank credit
facility currently  prohibits  the  payment  of  dividends.  Under  the  General
Corporation Law of the State of Delaware, a corporation's board of directors may
declare and pay dividends only out of surplus or current net profits.
 
                                       14
<PAGE>
                                 CAPITALIZATION
 
    The  following table sets forth the  pro forma capitalization of the Company
as of March  31, 1996, (i)  to give effect  to the automatic  conversion of  all
outstanding  shares of the Company's Preferred Stock,  Class A Stock and Class B
Stock into  shares of  Common Stock  immediately  prior to  the closing  of  the
Offering  and (ii), as adjusted, to reflect  the issuance of 2,800,000 shares of
Common Stock pursuant to the Offering at an assumed offering price of $9.00  per
share  and  after deducting  the  underwriting discount  and  estimated offering
expenses payable by the Company.
 
<TABLE>
<CAPTION>
                                                                                          MARCH 31, 1996
                                                                                 --------------------------------
                                                                                    PRO FORMA       AS ADJUSTED
                                                                                 ---------------  ---------------
<S>                                                                              <C>              <C>
Current installments of long-term debt and obligations under capital leases....  $       829,622  $       829,622
                                                                                 ---------------  ---------------
Long-term debt and obligations under capital leases, net of current
 installments..................................................................  $       950,238  $       950,238
                                                                                 ---------------  ---------------
Stockholders' equity:
  Preferred Stock, $.01 par value per share, 6,000,000 shares authorized, none
   issued or outstanding
  Common Stock, $.01 par value, 20,000,000 shares authorized; 6,564,048 and
   9,364,048 shares issued and outstanding(1)..................................           65,640           93,640
Additional paid-in capital.....................................................       22,759,944       45,567,944
Accumulated deficit............................................................      (14,123,924)     (14,123,924)
                                                                                 ---------------  ---------------
Total stockholders' equity.....................................................        8,701,660       31,537,660
                                                                                 ---------------  ---------------
Total capitalization...........................................................  $    10,481,520  $    33,317,520
                                                                                 ---------------  ---------------
                                                                                 ---------------  ---------------
</TABLE>
 
- --------------------------
(1) Excludes 1,445,904 shares of Common Stock issuable upon exercise of  options
    and warrants outstanding at March 31, 1996.
 
                                       15
<PAGE>
                                    DILUTION
 
    The  net  tangible  book  value  of  the  Company  at  March  31,  1996, was
approximately $8.4 million,  or $1.28 per  share of Common  Stock, after  giving
effect  to the automatic  conversion of all outstanding  shares of the Company's
Preferred Stock, Class A  Stock and Class  B Stock into  shares of Common  Stock
immediately  prior to the  closing of the  Offering. After giving  effect to the
sale by the  Company of the  2,800,000 shares  of Common Stock  pursuant to  the
Offering  (at an assumed  initial public offering  price of $9.00  per share and
after deducting  the  underwriting  discount  and  estimated  offering  expenses
payable  by the  Company), the pro  forma net  tangible book value  at such date
would have been approximately $31.2 million or $3.33 per share of Common  Stock.
This  represents an immediate increase  in net tangible book  value of $2.05 per
share to existing stockholders and an  immediate dilution of $5.67 per share  to
new investors purchasing shares in the Offering. The following table illustrates
the per share dilution to new investors:
 
<TABLE>
<S>                                                                    <C>        <C>
Assumed initial public offering price per share......................             $    9.00
  Net tangible book value per share at March 31, 1996(1).............  $    1.28
  Increase attributable to new investors.............................       2.05
                                                                       ---------
Pro forma net tangible book value per share after the Offering.......                  3.33
                                                                                  ---------
Dilution per share to new investors(2)...............................             $    5.67
                                                                                  ---------
                                                                                  ---------
</TABLE>
 
- --------------------------
(1) Net  tangible book value  per share is determined  by dividing the Company's
    tangible net  worth (tangible  assets  less liabilities)  by the  number  of
    shares  of Common  Stock outstanding. Net  tangible book value  per share of
    Common Stock excludes intangibles of $326,806, or $.05 per share.
 
(2) Dilution per share is determined by  subtracting the pro forma net  tangible
    book  value per  share after  the Offering  from the  assumed initial public
    offering price.
 
    Assuming the Underwriters' over-allotment option  is exercised in full,  pro
forma net tangible book value upon completion of the Offering would be $3.55 per
share,  the immediate increase  in pro forma  net tangible book  value of shares
owned by  existing stockholders  would be  $2.27 per  share, and  the  immediate
dilution to the new investors would be $5.45 per share.
 
    The  following table sets forth, as of  March 31, 1996, the number of shares
of Common  Stock  (after  giving  effect to  the  automatic  conversion  of  all
outstanding  shares of the Company's Preferred Stock,  Class A Stock and Class B
Stock into  shares of  Common Stock  immediately  prior to  the closing  of  the
Offering) previously purchased from the Company, the total consideration paid to
the  Company and  the average price  per share  paid (i) by  existing holders of
Common Stock for  shares acquired during  the last  five years and  (ii) by  the
investors purchasing shares of Common Stock in the Offering, assuming an initial
public offering price of $9.00 per share.
 
<TABLE>
<CAPTION>
                                                    SHARES PURCHASED(1)       TOTAL CONSIDERATION       AVERAGE
                                                   ----------------------  -------------------------     PRICE
                                                     NUMBER      PERCENT       AMOUNT       PERCENT    PER SHARE
                                                   -----------  ---------  --------------  ---------  -----------
<S>                                                <C>          <C>        <C>             <C>        <C>
Existing stockholders............................    6,564,048      70.1%  $   16,313,701      39.3%   $    2.49
New investors....................................    2,800,000      29.9%  $   25,200,000      60.7%   $    9.00
                                                   -----------  ---------  --------------  ---------
                                                     9,364,048     100.0%  $   41,513,701     100.0%
                                                   -----------  ---------  --------------  ---------
                                                   -----------  ---------  --------------  ---------
</TABLE>
 
- ------------------------
(1) Excludes  1,445,904 shares of Common Stock issuable upon exercise of options
    and warrants outstanding at March 31,  1996, at a weighted average  exercise
    price of $2.16.
 
                                       16
<PAGE>
                            SELECTED FINANCIAL DATA
 
    The  selected financial data of the Company  set forth below for each of the
years ended December 31, 1993, 1994 and 1995, and at December 31, 1994 and 1995,
have been derived from the audited financial statements of the Company  included
elsewhere  in this  Prospectus. Such financial  statements have  been audited by
Arthur Andersen LLP, independent public accountants. The selected financial data
for the years ended December 31, 1991  and 1992, and at December 31, 1991,  1992
and 1993, are derived from the audited financial statements of the Company which
are  not  included in  the  Prospectus and  which  have been  audited  by Arthur
Andersen LLP, independent  public accountants. The  selected financial data  set
forth  below for each of the three-month  periods ended March 31, 1995 and 1996,
and at March 31, 1996, have been derived from unaudited financial statements  of
the  Company included elsewhere in this Prospectus. In the opinion of management
of the Company,  such unaudited financial  information includes all  adjustments
(consisting  of  normal  recurring  accruals) considered  necessary  for  a fair
presentation of the Company's results of  operations for the periods then  ended
and  the Company's financial position as of such date. Operating results for the
three-month period ended March 31, 1996,  are not necessarily indicative of  the
results for the entire year. This information should be read in conjunction with
"Management's  Discussion  and Analysis  of Financial  Condition and  Results of
Operations" and the  Company's Financial Statements  and Notes thereto  included
elsewhere in this Prospectus.
<TABLE>
<CAPTION>
                                                                                            THREE MONTHS ENDED
                                                  YEAR ENDED DECEMBER 31,                       MARCH 31,
                                   -----------------------------------------------------  ----------------------
                                     1991       1992       1993       1994       1995        1995        1996
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
                                                       (IN THOUSANDS, EXCEPT PER SHARE DATA)
<S>                                <C>        <C>        <C>        <C>        <C>        <C>          <C>
STATEMENT OF OPERATIONS DATA:
Revenue..........................  $   2,145  $   4,813  $   9,348  $  14,531  $  19,758   $   4,619   $   5,908
Operating expenses:
  Direct cost of services and
   products......................      1,161      2,019      3,893      5,891      7,354       1,658       2,138
  Selling, general and
   administrative expenses.......      2,127      3,796      6,308      8,765      9,423       2,255       2,862
  Research and development.......        416        552      1,252      1,969      2,267         558         644
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
    Total operating expenses.....      3,704      6,367     11,453     16,625     19,044       4,471       5,644
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
  Income (loss) from
   operations....................     (1,559)    (1,554)    (2,105)    (2,094)       714         148         264
Other income (expense)...........         93         42        (63)      (203)      (181)        (56)        (33)
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
Net income (loss)................  $  (1,466) $  (1,512) $  (2,168) $  (2,297) $     533   $      92   $     231
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
Pro forma net income (loss) per
 share(1)........................  $    (.61) $    (.37) $    (.41) $    (.38) $     .07   $     .01   $     .03
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
Shares used in computing pro
 forma net income (loss) per
 share(1)........................      2,396      4,093      5,233      6,104      7,296       6,588       7,523
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
                                   ---------  ---------  ---------  ---------  ---------  -----------  ---------
 
<CAPTION>
 
                                                       DECEMBER 31,
                                   -----------------------------------------------------   MARCH 31,
                                     1991       1992       1993       1994       1995        1996
                                   ---------  ---------  ---------  ---------  ---------  -----------
                                                                  (IN THOUSANDS)
<S>                                <C>        <C>        <C>        <C>        <C>        <C>          <C>
BALANCE SHEET DATA:
Cash and cash equivalents........  $   2,140  $   3,002  $   1,193  $   1,823  $   3,125   $   1,301
Working capital..................      1,653      2,875      1,618      2,911      5,904       5,086
Total assets.....................      2,914      4,777      5,017      7,946     12,494      12,034
Long-term debt...................        189         63      1,009      2,063      1,666         950
Accumulated deficit..............     (8,909)   (10,421)   (12,590)   (14,887)   (14,355)    (14,124)
Total stockholders' equity.......      1,813      3,536      1,367      3,869      8,425       8,702
</TABLE>
 
- --------------------------
(1) Computed on the basis described in Note 2 to the Financial Statements.
 
                                       17
<PAGE>
          MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                           AND RESULTS OF OPERATIONS
 
    THIS   PROSPECTUS   CONTAINS,   IN  ADDITION   TO   HISTORICAL  INFORMATION,
FORWARD-LOOKING STATEMENTS THAT INVOLVE  RISKS AND UNCERTAINTIES. THE  COMPANY'S
ACTUAL  RESULTS COULD DIFFER MATERIALLY. FACTORS  THAT COULD CAUSE OR CONTRIBUTE
TO SUCH DIFFERENCES INCLUDE, BUT ARE  NOT LIMITED TO, THOSE DISCUSSED BELOW,  IN
"RISK FACTORS" AND "BUSINESS" AND ELSEWHERE IN THIS PROSPECTUS.
 
OVERVIEW
 
    UroCor  provides  a  broad range  of  diagnostic services  for  the clinical
management of certain urological cancers and diseases. The Company's goal is  to
complement  its diagnostic  services with  therapeutic products  and information
systems in order to  become the leading disease  management company serving  the
urology  market. Through its four  business groups, UroDiagnostics, UroSciences,
UroTherapeutics and  Disease  Management  Information Systems,  the  Company  is
developing  an  integrated disease  management approach  to  serve the  needs of
urologists and managed  care organizations  for the  diagnostic, prognostic  and
therapeutic care of patients throughout a disease cycle.
 
    The  Company  currently  derives  substantially  all  of  its  revenue  from
diagnostic products and services that  its UroDiagnostics Group provides to  the
urology  market  to  assist  in  the  diagnosis,  prognosis  and  management  of
urological diseases. The Company  recognizes revenue when  products are sold  or
services  are rendered. The  Company typically bills  various third-party payors
for its products and services, including governmental programs such as Medicare,
private insurance and managed  care plans, as well  as individual patients.  For
the  year ended  December 31,  1995, approximately  58%, 31%,  8% and  3% of the
Company's revenue was  attributable to Medicare,  private insurance and  managed
care, individual patients and physicians and hospitals, respectively.
 
    The  Company  monitors the  collection  quality of  its  accounts receivable
through analytical review  of aging  categories by payor  group and  collections
performance  compared to historical trends.  Possible uncollectible accounts are
provided for by charges  to operations, which are  included in Selling,  General
Administrative  expenses in  the accompanying financial  statements. The Company
determines its  provision  for doubtful  accounts  on a  monthly  basis  through
specific  reserve  percentages by  payor aging  categories,  as well  as general
reserve percentages, each based  on past experience and  adjusted as changes  in
conditions  become  known.  The  Company has  historically  not  experienced any
material write-off or collection  problems for which  adequate reserves had  not
been established through its regular provision for doubtful accounts.
 
    During  the three months  ended March 31, 1996,  the Company's allowance for
doubtful accounts declined from December 31, 1995, while the related balance  of
accounts receivable increased during this period. This decrease in the allowance
was  due primarily to the write-off  of certain delinquent receivables for which
reserves had been previously allocated.
 
    The Company generally has  been able to  offset continuing downward  pricing
pressures  from  Medicare  and  other  third-party  payors  by  introducing  new
diagnostic products  and  enhancements  to  existing  products  as  well  as  by
implementing  selective  price increases.  The price  increases effected  by the
Company in 1993, 1994,  1995 and the  first three months  of 1996 accounted  for
increased revenue in those periods of $162,000, $278,000, $284,000 and $116,000,
respectively.  The net result  has been an  increase in the  average revenue per
specimen received  by the  Company  during 1993  through  1995. In  the  future,
however, the Company expects to introduce additional products to its client base
which may reduce the average revenue per specimen.
 
    The  Company's revenue has increased over  the past five years primarily due
to expansion of its physician client  base, increased market penetration of  its
diagnostic  products  and services,  introduction  of new  products  and product
enhancements and selected  price increases.  During that  period, the  Company's
revenue  has increased generally at a faster rate than total operating expenses,
and, therefore, total operating expenses have declined generally as a percentage
of revenue.  Direct expenses  as a  percentage of  revenue for  the first  three
months    of   1996   totaled   36.2%,   a   continuing   decline   from   prior
 
                                       18
<PAGE>
annual periods, although an increase compared to the first three months of 1995.
These trends  result from  spreading fixed  processing costs  over higher  sales
volumes.  The Company expects such trends generally to continue primarily due to
further expansion of its client base and market penetration of its products  and
services,  although it does not expect  the decrease in total operating expenses
as a percentage of revenue to continue at  the same rate as over the past  three
years. The Company's actual performance may differ materially from the Company's
expectations.  The factors  that could cause  or contribute  to such differences
include, but are not limited to, those discussed in "Risk Factors".
 
    In connection with  the grant to  employees of options  to purchase  295,000
shares  of Common Stock in December 1995 at  a per share exercise price of $1.75
and considering the anticipated initial public offering price range of $8.00  to
$10.00  per share of the shares of Common Stock offered hereby and certain other
events, the Company has estimated the adjusted fair value of Common Stock at the
date of grant of the options to be  $3.25 per share. The Company will treat  the
difference  between the adjusted fair value and the actual exercise price of the
options as imputed compensation  expense. As a result,  the Company will  record
non-cash charges to operations of approximately $33,500 per quarter, or $134,000
annually,  in each  of the  years ending  December 31,  1996, 1997  and 1998 and
approximately $5,000 per quarter  or $20,000 annually in  each of the two  years
ending  December 31, 1999 and  2000. The quarterly charge  has been reflected in
the Company's results of operations for the three months ended March 31, 1996.
 
    No income  tax expense  was recorded  for 1995,  due to  utilization of  the
Company's  net operating loss  carryforwards. At December  31, 1995, the Company
had net operating loss carryforwards of approximately $9.6 million available  to
reduce future taxable income, subject to certain annual limitations.
 
RESULTS OF OPERATIONS
 
    The  following  table  sets  forth certain  operating  data  expressed  as a
percentage of revenue for each period indicated:
 
<TABLE>
<CAPTION>
                                                                                         THREE MONTHS ENDED
                                                        YEAR ENDED DECEMBER 31,              MARCH 31,
                                                   ----------------------------------  ----------------------
                                                      1993        1994        1995        1995        1996
                                                   ----------  ----------  ----------  ----------  ----------
<S>                                                <C>         <C>         <C>         <C>         <C>
Revenue..........................................      100.0%      100.0%      100.0%      100.0%      100.0%
Operating expenses:
  Direct cost of services and products...........       41.6        40.5        37.2        35.9        36.2
  Selling, general and administrative expenses...       67.5        60.3        47.7        48.8        48.4
  Research and development.......................       13.4        13.6        11.5        12.1        10.9
                                                       -----       -----       -----       -----       -----
    Total operating expenses.....................      122.5       114.4        96.4        96.8        95.5
                                                       -----       -----       -----       -----       -----
  Income (loss) from operations..................      (22.5)      (14.4)        3.6         3.2         4.5
Other income (expense)...........................       (0.7)       (1.4)       (0.9)       (1.2)       (0.6)
                                                       -----       -----       -----       -----       -----
Income (loss) before income taxes................      (23.2)      (15.8)        2.7         2.0         3.9
                                                       -----       -----       -----       -----       -----
Income taxes.....................................      --          --          --          --          --
                                                       -----       -----       -----       -----       -----
Net income (loss)................................      (23.2)%     (15.8)%       2.7%        2.0%        3.9%
                                                       -----       -----       -----       -----       -----
                                                       -----       -----       -----       -----       -----
</TABLE>
 
    THREE MONTHS ENDED MARCH 31, 1996 COMPARED TO THREE MONTHS ENDED MARCH 31,
1995
 
    REVENUE.  Revenue increased  27.9%, from approximately  $4.6 million in  the
first  three months  of 1995  to approximately $5.9  million in  the first three
months of 1996. This increase was due primarily to a 44.3% increase in  specimen
volume,  attributable primarily to  expansion of the  Company's physician client
base, increased utilization  of the Company's  services by its  clients and  new
product introductions
 
                                       19
<PAGE>
and  enhancements. The introduction in February 1996 of the Company's new kidney
stone product line and an increase in serum based testing which have an  average
revenue  per specimen of  $40 to $70  each served to  reduce the average revenue
realized per specimen.
 
    DIRECT COST OF SERVICES AND PRODUCTS.  Direct cost of services and  products
increased  28.9%, from approximately  $1.7 million in the  first three months of
1995 to  approximately $2.1  million in  the first  three months  of 1996.  This
increase  was due principally  to higher personnel costs  of $207,000 and supply
and distribution costs of $217,000 resulting from increased specimen volume.  As
a  percentage of revenue, direct expenses increased to 36.2% for the first three
months of  1996  compared to  35.9%  for the  first  three months  of  1995  due
principally  to expenses  related to  the start-up  of the  Company's new kidney
stone line.
 
    SELLING,  GENERAL  AND  ADMINISTRATIVE  EXPENSES.    Selling,  general   and
administrative  expenses increased 27.0%, from approximately $2.3 million in the
first three months  of 1995  to approximately $2.9  million in  the first  three
months  of 1996.  This increase  was due  principally to  increases in personnel
costs of  $352,000 due  to  additional marketing  and  sales staff  and  billing
personnel,  as  well  as increases  in  promotional  expenses of  $66,000.  As a
percentage of revenue, selling, general  and administrative expenses were  48.4%
for  the first three months of 1996 compared to 48.8% for the first three months
of 1995.
 
    RESEARCH AND  DEVELOPMENT.    Research and  development  expenses  increased
15.3%,  from  approximately  $558,000  in  the first  three  months  of  1995 to
approximately $644,000 in the first three months of 1996. This increase was  due
principally  to  additional collaborative  research  projects for  the potential
development of new products and services.  As a percentage of revenue,  research
and  development expenses were 10.9% for the first three months of 1996 compared
to 12.1% for the first three months of 1995. Research and development costs  are
charged to operating expenses as incurred.
 
    OTHER INCOME (EXPENSE).  Interest income increased 48.9%, from approximately
$16,000 for the first three months of 1995 to approximately $23,000 in the first
three  months  of 1996.  Interest  expense decreased  20.4%,  from approximately
$71,000 in the first three months of 1995 to approximately $57,000 in the  first
three months of 1996, due to a decrease in average principal balances of capital
leases and the Company's bank credit facility.
 
    YEAR ENDED DECEMBER 31, 1995 COMPARED TO YEAR ENDED DECEMBER 31, 1994
 
    REVENUE.   Revenue increased 36.0%, from approximately $14.5 million in 1994
to approximately $19.8  million in 1995.  This increase was  due primarily to  a
19.3%  increase in specimen  volume combined with  increased average revenue per
specimen resulting from changes in product  mix and the effect of the  marketing
of  prostate  histology  sextant testing  services  for  the full  year  in 1995
compared to ten months in 1994.
 
    DIRECT COST OF SERVICES AND PRODUCTS.  Direct cost of services and  products
increased  24.8%, from approximately $5.9 million  in 1994 to approximately $7.4
million in 1995. This increase was  due principally to higher personnel,  supply
and distribution costs resulting from increased specimen volume. As a percentage
of revenue, direct expenses were 37.2% for 1995 compared to 40.5% in 1994.
 
    SELLING,   GENERAL  AND  ADMINISTRATIVE  EXPENSES.    Selling,  general  and
administrative expenses increased 7.5%, from approximately $8.8 million in  1994
to  approximately $9.4  million in  1995. This  increase was  due principally to
increased costs of sales force personnel  and marketing staff for the full  year
in 1995, as the managed care sales group and several other positions were filled
in  mid 1994. Promotional expenses related to the managed care sales effort also
increased  due  to  activity  for  the  full  year  in  1995  compared  to   the
approximately  six months  following the  deployment of  the managed  care sales
force  in  mid  1994.  As  a   percentage  of  revenue,  selling,  general   and
administrative expenses were 47.7% for 1995 compared to 60.3% in 1994.
 
    RESEARCH  AND  DEVELOPMENT.   Research  and  development  expenses increased
15.1%, from approximately $2.0 million in 1994 to approximately $2.3 million  in
1995. This increase was due principally to
 
                                       20
<PAGE>
additional  collaborative research projects for the development of potential new
products and services, as well as internal research laboratory personnel  costs.
As  a percentage  of revenue, research  and development expenses  were 11.5% for
1995 compared to 13.6% in 1994.
 
    OTHER INCOME (EXPENSE).  Interest income increased 4.8%, from  approximately
$104,000  in 1994 to approximately $109,000  in 1995. Interest expense decreased
5.5%, from approximately $307,000 in 1994 to approximately $290,000 in 1995, due
to a decrease in average principal balances of capital leases and the  Company's
bank credit facility during 1995.
 
    YEAR ENDED DECEMBER 31, 1994 COMPARED TO YEAR ENDED DECEMBER 31, 1993
 
    REVENUE.   Revenue increased 55.4%, from  approximately $9.3 million in 1993
to approximately $14.5  million in 1994.  This increase was  due primarily to  a
42.2% increase in specimen volume, as well as an increase in the average revenue
per  specimen principally resulting from  the introduction of prostate histology
sextant testing in March 1994.
 
    DIRECT COST OF SERVICES AND PRODUCTS.  Direct cost of services and  products
increased  51.3%, from approximately $3.9 million  in 1993 to approximately $5.9
million in  1994. This  increase  was due  principally to  increased  personnel,
supplies  and logistics costs resulting from higher specimen volumes, as well as
changes in product mix due to the introduction of the prostate histology sextant
testing service. As a percentage of revenue, direct expenses were 40.5% for 1994
compared to 41.6% in 1993.
 
    SELLING,  GENERAL  AND  ADMINISTRATIVE  EXPENSES.    Selling,  general   and
administrative expenses increased 38.9%, from approximately $6.3 million in 1993
to  approximately $8.8 million in 1994. This  increase was due to an increase of
32 additional personnel  in 1994  over 1993,  principally a  managed care  sales
group,  deployed in  mid 1994, as  well as increased  sales support, information
services and billing personnel. In addition, marketing and promotional  expenses
increased related to the managed care sales group, new diagnostic services and a
higher level of sales activity. As a percentage of revenue, selling, general and
administrative expenses were 60.3% for 1994 compared to 67.5% in 1993.
 
    RESEARCH  AND  DEVELOPMENT.   Research  and  development  expenses increased
57.3%, from approximately $1.3 million in 1993 to approximately $2.0 million  in
1994.  This increase  was due principally  to an increase  in research personnel
from 14 in 1993 to 21 in 1994, resulting in higher personnel and supplies costs,
as well  as an  increase  in collaborative  research  project fundings  for  the
development  of potential new products and services. As a percentage of revenue,
research and development expenses were 13.6% for 1994 compared to 13.4% in 1993.
 
    OTHER  INCOME   (EXPENSE).     Interest   income  increased   130.3%,   from
approximately  $45,000 in 1993 to approximately  $104,000 in 1994, due to higher
average balances of  cash and  cash equivalents during  1994. Interest  expenses
increased  183.0%, from approximately $109,000 in 1993 to approximately $307,000
in 1994, due to an increase in average principal balances of capital leases  and
the Company's bank credit facility during 1994.
 
QUARTERLY RESULTS OF OPERATIONS
 
    The  following tables  present the Company's  results of  operations for the
last 13 calendar quarters  and the percentage relationship  of certain items  to
revenue  for such quarters. This data is  unaudited and includes, in the opinion
of  the  Company's  management,  all  adjustments  (consisting  only  of  normal
recurring  adjustments) necessary to present fairly  the data in accordance with
generally  accepted  accounting  principles.  Such  quarterly  results  are  not
necessarily indicative of future results of operations.
 
    The  Company's quarterly operating results are affected by a wide variety of
factors, many of which are outside the Company's control, that could  materially
and  adversely  affect revenue,  operating  expenses and  income.  These factors
include the  volume  and  timing  of  specimens  received,  competitive  pricing
pressures,  availability and cost of diagnostic  supplies, changes in the mix of
products sold,  seasonality related  to  the timing  of  patient visits  to  the
urologist's office as affected by weather and
 
                                       21
<PAGE>
insurance  deductible status, the timing and costs of new product and technology
introductions by the Company or its competitors, retention and expansion of  the
Company's sales force and timing of payments from Medicare and other third-party
payors.
<TABLE>
<CAPTION>
                                                          DOLLARS IN THOUSANDS
                               ---------------------------------------------------------------------------
                                              1993                                   1994
                               -----------------------------------   -------------------------------------
                                 Q1      Q2        Q3        Q4        Q1        Q2        Q3        Q4
                               ------  -------   -------   -------   -------   -------   -------   -------
<S>                            <C>     <C>       <C>       <C>       <C>       <C>       <C>       <C>
Revenue......................  $1,804   $2,283    $2,252    $3,009    $2,786    $3,487    $3,741    $4,517
                               ------  -------   -------   -------   -------   -------   -------   -------
Operating expenses:
  Direct costs of services
   and products..............     844    1,033       959     1,057     1,193     1,346     1,559     1,793
  Selling, general and
   administrative expenses...   1,471    1,504     1,653     1,680     1,873     2,041     2,383     2,468
  Research and development...     184      296       378       394       404       457       517       591
                               ------  -------   -------   -------   -------   -------   -------   -------
  Income (loss) from
   operations................    (695)    (550)     (738)     (121)     (684)     (357)     (718)     (335)
Other income (expense).......      13        6       (28)      (54)      (66)      (37)      (41)      (59)
                               ------  -------   -------   -------   -------   -------   -------   -------
Income (loss) before income
 taxes.......................    (682)    (544)     (766)     (176)     (750)     (394)     (759)     (394)
Income taxes (benefit).......    --      --        --        --        --        --        --        --
                               ------  -------   -------   -------   -------   -------   -------   -------
Net income (loss)............  $ (682)  $ (544)   $ (766)   $ (176)   $ (750)   $ (394)   $ (759)   $ (394)
                               ------  -------   -------   -------   -------   -------   -------   -------
                               ------  -------   -------   -------   -------   -------   -------   -------
 
<CAPTION>
 
                                               1995                     1996
                               -------------------------------------   -------
                                 Q1        Q2        Q3        Q4        Q1
                               -------   -------   -------   -------   -------
<S>                            <C>       <C>       <C>       <C>       <C>
Revenue......................   $4,619    $4,824    $4,784    $5,531    $5,908
                               -------   -------   -------   -------   -------
Operating expenses:
  Direct costs of services
   and products..............    1,658     1,749     1,849     2,098     2,138
  Selling, general and
   administrative expenses...    2,255     2,342     2,276     2,550     2,862
  Research and development...      558       540       540       629       644
                               -------   -------   -------   -------   -------
  Income (loss) from
   operations................      148       193       119       254       264
Other income (expense).......      (56)      (63)      (40)      (22)      (33)
                               -------   -------   -------   -------   -------
Income (loss) before income
 taxes.......................       92       130        79       232       231
Income taxes (benefit).......    --        --        --        --        --
                               -------   -------   -------   -------   -------
Net income (loss)............    $  92     $ 130     $  79     $ 232     $ 231
                               -------   -------   -------   -------   -------
                               -------   -------   -------   -------   -------
</TABLE>
<TABLE>
<CAPTION>
                                                       AS A PERCENTAGE OF REVENUE
                               ---------------------------------------------------------------------------
                                              1993                                   1994
                               -----------------------------------   -------------------------------------
                                 Q1      Q2        Q3        Q4        Q1        Q2        Q3        Q4
                               ------  -------   -------   -------   -------   -------   -------   -------
<S>                            <C>     <C>       <C>       <C>       <C>       <C>       <C>       <C>
Revenue......................   100.0%   100.0%    100.0%    100.0%    100.0%    100.0%    100.0%    100.0%
Operating expenses:
  Direct costs of services
   and products..............    46.8     45.3      42.6      35.1      42.8      38.6      41.7      39.7
  Selling, general and
   administrative expenses...    81.5     65.8      73.4      55.8      67.2      58.5      63.7      54.6
  Research and development...    10.2     13.0      16.8      13.1      14.5      13.1      13.8      13.1
                               ------  -------   -------   -------   -------   -------   -------   -------
  Income (loss) from
   operations................   (38.5)   (24.1)    (32.8)     (4.0)    (24.5)    (10.2)    (19.2)     (7.4)
Other income (expense).......     0.7      0.3      (1.2)     (1.8)     (2.4)     (1.1)     (1.1)     (1.3)
                               ------  -------   -------   -------   -------   -------   -------   -------
Income (loss) before income
 taxes.......................   (37.8)   (23.8)    (34.0)     (5.8)    (26.9)    (11.3)    (20.3)     (8.7)
Income taxes (benefit).......    --      --        --        --        --        --        --        --
                               ------  -------   -------   -------   -------   -------   -------   -------
Net income (loss)............   (37.8)%   (23.8)%   (34.0)%    (5.8)%   (26.9)%   (11.3)%   (20.3)%    (8.7)%
                               ------  -------   -------   -------   -------   -------   -------   -------
                               ------  -------   -------   -------   -------   -------   -------   -------
 
<CAPTION>
 
                                               1995                     1996
                               -------------------------------------   -------
                                 Q1        Q2        Q3        Q4        Q1
                               -------   -------   -------   -------   -------
<S>                            <C>       <C>       <C>       <C>       <C>
Revenue......................    100.0%    100.0%    100.0%    100.0%    100.0%
Operating expenses:
  Direct costs of services
   and products..............     35.9      36.3      38.7      37.9      36.2
  Selling, general and
   administrative expenses...     48.8      48.5      47.6      46.1      48.4
  Research and development...     12.1      11.2      11.3      11.4      10.9
                               -------   -------   -------   -------   -------
  Income (loss) from
   operations................      3.2       4.0       2.4       4.6       4.5
Other income (expense).......     (1.2)     (1.3)     (0.8)     (0.4)     (0.6)
                               -------   -------   -------   -------   -------
Income (loss) before income
 taxes.......................      2.0       2.7       1.6       4.2       3.9
Income taxes (benefit).......    --        --        --        --        --
                               -------   -------   -------   -------   -------
Net income (loss)............      2.0%      2.7%      1.6%      4.2%      3.9%
                               -------   -------   -------   -------   -------
                               -------   -------   -------   -------   -------
</TABLE>
 
LIQUIDITY AND CAPITAL RESOURCES
 
    Since  the Company's  reorganization in 1991,  the Company  has financed its
operations primarily through  the issuance  of equity  securities, resulting  in
aggregate proceeds of approximately $16.3 million. The Company's working capital
needs have increased during that period and are expected to continue to increase
as  the  Company  expands its  operations.  Since 1994,  the  Company's Medicare
intermediary and certain other third-party  payors have increased the amount  of
time  between  their receipt  of  claims for  reimbursement  and payment  to the
Company. At  March 31,  1996, the  Company's  average number  of days  sales  in
receivables  was  approximately 74  compared to  49 at  December 31,  1994. Such
delays in  payments to  the  Company have  resulted  in the  Company's  accounts
receivable  increasing  at a  rate greater  than the  revenue growth  rate. Such
delays also have affected the Company's cash flow from operations. As a  result,
the  Company has used its  bank credit facility from  time to time to supplement
its cash flows.
 
    As of  March  31,  1996,  the  Company had  cash  and  cash  equivalents  of
approximately $1.3 million and working capital of $5.1 million. Net cash used in
operating  activities  was approximately  $2.3  million, $2.4  million  and $0.5
million in 1993, 1994 and 1995, respectively and approximately $0.5 million  for
the three months ended March 31, 1996. The net cash used in operating activities
in  1995  was  primarily the  result  of  a $1.9  million  increase  in accounts
receivable, offset  in  part  by  net  income  of  approximately  $0.5  million,
depreciation  and amortization of approximately $0.9  million and an increase in
accrued compensation  of  approximately  $0.2  million. The  net  cash  used  in
operating activities
 
                                       22
<PAGE>
for the three months ended March 31, 1996, was primarily the result of increases
in  accounts  receivable  and other  current  assets  of $0.6  million  and $0.4
million, respectively,  offset  in part  by  net income  of  approximately  $0.2
million  and  by depreciation  and  amortization and  stock  option compensation
expense totaling approximately $0.3 million. The Company believes that it  could
maintain its current level of operations using its existing cash resources, bank
credit facility, equipment leases and cash flow from operations.
 
    Net cash used in investing activities was approximately $2.1 million in 1995
and  consisted primarily of capital expenditures  of $1.4 million for laboratory
and computer equipment and office equipment and improvements and a $0.5  million
milestone  payment  under the  distribution rights  agreement for  the Company's
proposed BCG therapeutic product. Net cash provided by financing activities  was
$3.9  million  for  1995 and  consisted  primarily  of net  proceeds  from stock
issuances  ($4.0  million)  and  from  borrowings  under  capital  leases  ($0.8
million),  offset in part  by principal payments under  capital leases and other
indebtedness ($0.7 million) and repayments under the bank credit facility  ($0.3
million).  For the three months ended March 31, 1996, net cash used in investing
activities was  approximately  $0.6  million, consisting  primarily  of  capital
expenditures of approximately $0.5 million for laboratory and computer equipment
and   office  equipment,  and   net  cash  used   in  financing  activities  was
approximately $0.7 million, primarily due  to reduction of borrowings under  the
Company's bank credit facility.
 
    The  Company's bank credit facility permits the Company to borrow up to $3.0
million and is secured by accounts receivable  and a lien on all other  tangible
assets,  which does  not include equipment  leased by the  Company under capital
leases. Funds borrowed under the credit facility bear interest monthly at a  per
annum  interest rate of prime plus 1.5% (9.75% as of March 31, 1996). The credit
facility expires in February 1997, and as of May 10, 1996, there were no amounts
borrowed under this credit facility.
 
    The Company's  capital expenditures  were approximately  $1.6 million,  $1.0
million,  $1.4 million and $0.5 million in 1993, 1994, 1995 and the three months
ended March  31,  1996, respectively.  While  future capital  expenditures  will
depend  upon a number  of factors, including the  progress of certain technology
acquisitions, the level of  such expenditures is expected  to increase over  the
historical  level  of  such expenditures.  The  Company intends  to  finance the
majority of these capital expenditures through lease financing arrangements  and
with  a portion of  the proceeds of  the Offering. The  Company historically has
been able to secure such lease financing on favorable terms. In April 1996,  the
Company  secured an increase in one of its existing capital leases of up to $1.5
million for future  capital expenditures  made through  March 1997.  At May  10,
1996,   the  Company  has  certain  cancellable  commitments  for  computer  and
laboratory information systems totalling approximately $600,000.
 
    In December 1994, the Company  obtained distribution rights to its  proposed
BCG  therapeutic product currently under FDA  review for marketing approval. The
total cost of the distribution  rights is $3.0 million,  which is being paid  in
installments  based on achievement of certain  milestones. An initial payment of
$750,000 was made  in December 1994,  and a second  installment of $500,000  was
paid  in 1995 after the product was submitted  for FDA review in April 1995. The
Company is obligated  to pay an  additional milestone payment  of $1.75  million
when or if the product completes the FDA approval process.
 
    The  Company anticipates  that its  operations and  growth strategy  will be
financed through the net  proceeds from the Offering,  operating cash flow,  its
existing  bank credit facility  and equipment leases.  The Company believes that
these sources  of funds  will be  sufficient to  satisfy the  Company's  capital
requirements  for at least 24 months.  There may be circumstances, however, that
would accelerate  the Company's  use  of proceeds  from  the Offering.  If  this
occurs,  the Company  may, from time  to time, incur  additional indebtedness or
issue, in public or private transactions, equity or debt securities. The Company
currently has no arrangements, however,  for additional financing and there  can
be no assurance that the Company will be able to attain requisite financing when
needed on acceptable terms.
 
                                       23
<PAGE>
                                    BUSINESS
 
OVERVIEW
 
    UroCor  provides  a  broad range  of  diagnostic services  for  the clinical
management of certain urological cancers and diseases. The Company's goal is  to
complement  its diagnostic  services with  therapeutic products  and information
systems in order to  become the leading disease  management company serving  the
urology  market. Through its four  business groups, UroDiagnostics, UroSciences,
UroTherapeutics and  Disease  Management  Information Systems,  the  Company  is
developing  an  integrated disease  management approach  to  serve the  needs of
urologists and managed  care organizations  for the  diagnostic, prognostic  and
therapeutic   care  of  patients  throughout  a  disease  cycle.  The  Company's
UroDiagnostics Group  provides  diagnostic  services to  over  1,400  urologists
nationwide.  This  group provides  comprehensive  diagnostic services  to detect
major urological diseases, predict prognosis of the patient's condition, monitor
the patient's therapy and  identify recurrence of  the disease. The  UroSciences
Group's  goal  is to  become  a leader  in  the development  and  application of
advanced  diagnostic  technologies  and   information  resources  for   managing
urological diseases. The UroTherapeutics Group was established to acquire rights
to  sell through  the Company's  existing sales  force urological pharmaceutical
products for use  in the  urologist's office. The  Company's Disease  Management
Information  Systems group  is designed to  provide urologists  and managed care
organizations with  access  to  the  Company's  proprietary  urological  disease
database,  disease management models and practice management guidelines in order
to improve the diagnosis and treatment of patients.
 
UROLOGY MARKET
 
    The urology market differs from  most other medical care markets,  primarily
because  of  the  distinctive  characteristics of  urological  diseases  and the
multiple roles  of the  urologist. The  urologist often  serves as  the  primary
diagnostician,  oncologist  and surgeon  for the  treatment of  prostate cancer,
bladder cancer,  kidney stone  disease and  other complex  urological  diseases.
Patients  with prostate  or bladder cancer  generally require  management of the
disease by the urologist  throughout a disease cycle  ranging from three to  ten
years.  The urologist requires sophisticated diagnostic and information services
throughout that period. Despite the urologist's need for comprehensive services,
currently, diagnostic services, therapeutic  products and information  resources
are  provided  primarily by  local hospitals,  pathology laboratories  and other
companies that do not focus exclusively on urological disease.
 
    UroCor serves the segment of the United States urology market consisting  of
over 7,500 office-based urologists, including those affiliated with managed care
organizations.  These urologists diagnose  and treat patients  who generally are
referred to  them by  another  physician for  prostate cancer,  bladder  cancer,
kidney  stone  disease and  other  complex urological  diseases.  An independent
survey estimated  that in  1993 there  were almost  15 million  urology  patient
visits  in  the  United  States.  The  American  Cancer  Society  estimates that
approximately 300,000  new cases  of prostate  cancer and  52,000 new  cases  of
bladder  cancer will be diagnosed in 1996,  resulting in medical costs in excess
of $5.0 billion.
 
STRATEGY
 
    To achieve its goal  of becoming the leading  disease management company  in
the  urology  market, UroCor  is pursuing  a  strategy directed  at establishing
itself as  a single  resource  for the  treatment  of prostate  cancer,  bladder
cancer,  kidney stone disease  and other complex diseases.  The Company plans to
expand its current diagnostic products and services and to offer therapeutic and
information systems products to serve the  needs of urologists and managed  care
organizations,  from initial indication of  selected urological diseases through
ultimate disease outcome. Through its UroDiagnostics and UroSciences Groups, the
Company currently  offers comprehensive  diagnostic, prognostic  and  monitoring
services  and  information.  The  Company  also  plans  to  offer,  through  its
UroTherapeutics Group and
 
                                       24
<PAGE>
Disease  Management  Information  Systems,  new  technologies  and  products  to
complement  its  diagnostic  services  business  and  to  provide  an integrated
resource for the management of urological  disease. The Company is pursuing  the
following strategies to achieve its objective:
 
    - INCREASE  MARKET PENETRATION OF OFFICE-BASED UROLOGISTS. Approximately 19%
      of the  more  than 7,500  office-based  urologists in  the  United  States
      currently  use  one or  more of  the  UroDiagnostic Group's  services. The
      Company has established a direct sales force, including specialists  whose
      focus is marketing to managed care organizations, dedicated solely to this
      market. Through the use of its specialized sales force and its emphasis on
      managed  care organizations, the Company expects to increase the number of
      urologists using its services and the  number of their patients served  by
      the Company.
 
    - EXPAND  USE OF  EXISTING PRODUCT  LINES. The  Company's UroDiagnostics and
      UroSciences Groups combine  their efforts to  improve the performance  of,
      education  relating  to  and clinical  evidence  supporting  the Company's
      existing diagnostic products and services.  In 1995, approximately 41%  of
      the  Company's  urologist  clients used  more  than one  of  the Company's
      services. The Company believes that it can increase the number of products
      used by each urologist through continued efforts by its specialized  sales
      force  to educate the  market on the  benefits of all  of UroCor's product
      lines.
 
    - EXPAND TOTAL  PRODUCT  OFFERING.  Through the  UroDiagnostics  Group,  the
      Company's direct sales force currently markets a broad range of diagnostic
      products  and  services  to  urologists  and  managed  care organizations.
      Through  its  UroSciences   Group,  UroTherapeutics   Group  and   Disease
      Management Information Systems, the Company intends to increase the number
      of  products and  services offered  to its  existing urologist  clients by
      developing, licensing  or acquiring  technologies and  products that  will
      expand  the total mix of products and services offered, including products
      that address additional urological diseases.
 
    - STRENGTHEN MARKET  TIES  WITH  ON-LINE  SYSTEMS.  The  Disease  Management
      Information  Systems group intends to link  the Company to its client base
      through a dedicated customized wide area network. The initial applications
      developed for  the  network are  intended  to improve  the  efficiency  of
      specimen  and patient information collection by  the urologists as well as
      the initial  reporting of  diagnostic results  and consultation  with  the
      Company's   pathologists.   UroCor  intends   to  strengthen   its  client
      relationships by developing and providing on-line disease pathway  models,
      decision support systems and patient outcome tracking ability.
 
DISEASE MANAGEMENT BUSINESS
 
    URODIAGNOSTICS GROUP -- PRODUCTS
 
    The  UroDiagnostics  Group  provides  diagnostic  services  for office-based
urologists. The  Company believes  that the  UroDiagnostics Group  provides  the
foundation  for  the development  of an  integrated disease  management company.
Unlike its competitors, who  generally offer varied products  and services to  a
broader  health  care market,  the  UroDiagnostics Group  provides comprehensive
diagnostic services to  detect and diagnose  certain major urological  diseases,
make  a prognosis of the patient's  condition, monitor the patient's therapy and
identify recurrence of the disease.
 
    The Company  emphasizes  customer  service, including  the  provision  of  a
comprehensive  detailed report  to the  referring physician  after completion of
each specimen analysis. The  Company's relations with  its clients are  enhanced
through  its regional customer service  representatives, who are responsible for
inquiries made by  referring physicians  and provide support  for the  Company's
sales force.
 
    The  Company's  sales of  diagnostic services  have grown  rapidly. UroCor's
client base increased from 380 at the end  of 1991 to 1,320 at the end of  1995.
The  UroDiagnostics Group generated  revenues of approximately  $19.6 million in
1995,  constituting   approximately   99%   of   the   Company's   revenue   for
 
                                       25
<PAGE>
1995.  The  Company attributes  its growth  to its  concentration on  building a
relationship  with  urologists  while  developing  and  servicing  an  important
marketing  and education channel to urologists which the Company believes it can
leverage through the delivery of additional products and services.
 
    The following chart sets forth the principal products and services currently
offered through the UroDiagnostics Group.
<TABLE>
  <S>                                <C>
                           UROLOGICAL DIAGNOSTIC SERVICES
 
<CAPTION>
 
                PRODUCT                               APPLICATION
  --------------------------------------------------------------------------------
  <S>                                <C>
   PROSTATE CANCER
    SERUM BASED
      PSA and PSA velocity           Detects and monitors disease
      Free/Total PSA*                Increases specificity of detection
    TISSUE BASED
      Sextant biopsy                 Increases diagnostic accuracy
      UroScore-Registered Trademark- Improves clinical staging and treatment
                                     selection
 
   BLADDER CANCER
    CELLULAR BASED
      Cellular pathology and DNA
   analysis                          Detects and diagnoses disease
      Antibody markers               Detects and diagnoses disease
    SOLUBLE ANTIGEN
      Antibody markers               Monitors disease
    TISSUE BASED
      Pathological examination       Provides definitive diagnosis and prognosis
      Antibody markers               Provides definitive diagnosis and prognosis
 
   MICROHEMATURIA
      Urine protein chemistry
   analysis                          Differentiates between upper or lower tract
                                     disease
      Microscopic examination        Differentiates between upper or lower tract
                                     disease
 
   KIDNEY STONES
      Stone analysis                 Determines stone structure and chemistry
      Serum chemistry                Identifies underlying disease
      24-hour soluble urine chemistry Assesses recurrence risk
   ------------------------
   *Not currently reimbursed by third-party payors, including Medicare.
</TABLE>
 
    PROSTATE CANCER PRODUCTS.  The  American Cancer Society estimates that  over
300,000  cases of  prostate cancer  will be  diagnosed in  1996, compared  to an
estimated 244,000 cases diagnosed in 1995. It also is estimated that one in five
males will suffer from the disease.  The Company believes that this increase  in
incidence  is due to  a variety of  factors, including the  increase in the life
expectancy of  the general  population and  improved prostate  cancer  detection
capabilities.  According to  the American Cancer  Society, the  medical costs of
prostate cancer in  the United  States are  estimated to  be approximately  $5.0
billion in 1996.
 
    Management  of  prostate cancer  requires the  urologist to  screen, detect,
diagnose, prognose and treat the patient and monitor progression of the disease.
UroCor has developed and markets products
 
                                       26
<PAGE>
and services that assist the urologist in  each of the diagnostic steps in  this
disease  cycle. UroCor's  PSA product  is used in  screening for  the disease to
improve the urologist's ability to  identify true positive cancer patients.  The
Company's  Free/Total PSA product is used for the same purpose and increases the
urologist's ability  to  detect  the  disease. UroCor  currently  is  using  the
Free/Total  PSA product on a  limited basis to build  a clinical case validating
its advantages prior to seeking reimbursement approval from third-party  payors.
The current preferred method for detecting the disease after the screening stage
is  the prostate biopsy. UroCor was an early proponent of the use of the sextant
biopsy technique  which has  been demonstrated  to increase  the possibility  of
finding small, localized tumor tissue in the prostate.
 
    After  screening  and  detection  of  prostate  cancer,  the  urologist must
accurately "stage" or classify the disease  to determine whether the cancer  has
spread  beyond the prostate gland. UroCor  developed its UroScore test to assist
the urologist in this step, which provides improvement in the ability to predict
whether the disease has progressed beyond the prostate gland. After staging  the
disease,  the urologist  determines whether to  treat the  disease with surgery,
radiation or  drug  therapy  or  simply to  monitor  its  progress.  UroCor  has
developed  expertise  in  advising  the  urologist  on  the  probability  that a
patient's cancer will progress. This information is enhanced by the Company's 11
pathologists who interpret  the prognostic information  in conjunction with  the
patient's  diagnostic pathology report. After reaching a treatment decision, the
urologist can monitor the patient for  evidence of recurrence or eradication  of
the disease by using the Company's PSA products.
 
    BLADDER  CANCER PRODUCTS.   According to  the American  Cancer Society, over
50,000 cases of bladder cancer  are estimated to be  diagnosed each year in  the
United  States.  Some  of  the  difficulties that  the  urologist  faces  in the
diagnosis and management of bladder cancer include detecting tumors at an  early
stage  and  assessing  the  aggressiveness of  tumors.  UroCor's  bladder cancer
products provide the urologist with analysis and information capabilities in all
significant aspects of the diagnosis and management of the disease. In addition,
unlike competing  products, UroCor's  bladder cellular  analysis incorporates  a
multi-modality  approach  that the  Company believes  provides, compared  to its
competitors, increased  levels of  analysis  and corresponding  improvements  in
specificity  and sensitivity of test results.  The Company's full bladder cancer
detection  program   combines   the  information   from   separate   microscopic
examinations of a patient's specimen using two different techniques, an analysis
of  the DNA in  cell nuclei, and the  use of one or  more specific biomarkers to
assist the pathologist test for the presence of cancer.
 
    MICROHEMATURIA PRODUCTS.  Microhematuria, or  the presence of small  amounts
of  blood in the urine, is one of the  conditions that may relate to a number of
urinary tract  diseases  and infections.  The  initial challenge  faced  by  the
urologist  in  diagnosing  the  underlying cause  of  the  microhematuria  is to
identify the source  of the  bleeding. UroCor's  microhematuria diagnostic  test
combines a microscopic examination of urine sediment by expert pathologists with
a  urine protein chemistry analysis to provide the urologist with information on
the probable  location of  the bleeding  and the  potential underlying  disease.
Because microhematuria may be one of the indications of bladder or other urinary
tract  cancer,  the  Company's comprehensive  diagnostic  analysis  provides the
urologist a  resource to  investigate and  confirm potential  causes of  bladder
cancer.
 
    KIDNEY STONE PRODUCTS.  Kidney stone disease typically requires physical and
chemical  analysis of the stone, and, in many cases, analysis of patients' urine
and serum specimens to assess the risk of disease recurrence. Traditionally, the
urologist was  required  to send  each  of the  kidney  stone, urine  and  serum
specimen  to different testing service providers. UroCor's kidney stone products
offer a complete program in which the urologist delivers all specimens to UroCor
and receives an integrated analysis and report.
 
                                       27
<PAGE>
    URODIAGNOSTICS GROUP -- SALES AND MARKETING
 
    The Company markets  its diagnostic services  to the segment  of the  market
consisting of more than 7,500 office-based urologists in the United States, many
of  whom are affiliated with one or  more managed care organizations. UroCor has
developed a sales  force dedicated and  trained to market  solely to  urologists
including  representatives  specializing  solely in  marketing  to  managed care
organizations.
 
    The Company's market  penetration has  advanced rapidly over  the past  five
years.  The  following chart  sets  forth historical  information  regarding the
urologist clients served by the Company and related information.
 
<TABLE>
<CAPTION>
                                                                              AT DECEMBER 31,
                                                         ---------------------------------------------------------
                                                           1991       1992       1993        1994         1995
                                                         ---------  ---------  ---------  -----------  -----------
<S>                                                      <C>        <C>        <C>        <C>          <C>
Number of urologist clients(1).........................        380        620      1,030        1,250        1,320
Number of specimens analyzed...........................     18,300     40,500     76,500      108,900      130,000
Average annual revenue per urologist...................  $   7,200  $   9,600  $  11,200  $    12,600  $    15,200
Percentage of multiple product users among total
 urologist clients.....................................         13%        19%        24%          34%          41%
Number of managed care contracts.......................         --          2          4           30           67
Total sales force......................................         11         28         31           35           35
</TABLE>
 
- --------------------------
(1) Represents the  number of  urologists  who used  the Company's  services  in
    December of each of the years indicated.
 
    The  Company intends to continue its penetration of the market by continuing
its efforts  to  expand its  client  base and  to  add additional  products  and
services to its product line for existing and future customers. The Company also
intends  to use its wide  area network link with its  client base to enhance the
regular two-way  communication between  the Company  and its  customers.  UroCor
believes that the wide area network will facilitate the introduction and support
of  new products and services  and increase the number  of products and services
used by existing clients.
 
    Commencing in  1994, the  Company began  focusing on  securing managed  care
contracts to permit UroCor to provide products and services to patients enrolled
in  these  health  care  organizations.  The  Company  currently  has  over  600
urologists  in  its   client  base   whose  patients  are   enrolled  in   these
organizations.  The Company intends  to increase its  penetration of the managed
care market by developing  products and services  specifically designed to  meet
the  cost control, quality  assurance and other  requirements imposed by managed
care organizations.
 
    In addition to its focus on the individual urologist client and managed care
organizations, the Company is concentrating its marketing efforts on identifying
and marketing products to the growing number of group practices and  independent
practice associations forming to specialize in urology.
 
    UROSCIENCES GROUP
 
    The  goal of the UroSciences Group is  to become a leader in the development
and  application  of  diagnostic  technologies  and  information  resources  for
managing  urological diseases. The UroSciences Group combines access to external
resources at  academic  centers  and  research  institutes  with  the  Company's
internal  development  and assessment  capabilities  to develop  and  launch new
technologies and products. The UroSciences Group's internal capabilities combine
the  expertise  of  five  different  laboratories  currently  staffed  with   23
scientists  and experienced  technical personnel. Participants  in the Company's
collaborative programs  include  M.D.  Anderson  Cancer  Center,  Johns  Hopkins
Medical Institutions, Baylor College of Medicine, Michigan Prostate Institute at
the University of Michigan, Michigan Cancer Foundation, Eastern Virginia Medical
School,  University of Texas  Southwestern Medical Center  and the University of
Washington.
 
    The UroSciences  Group has  developed a  database of  thousands of  cellular
tissue  and serum specimens of patients  related to the diagnosis, prognosis and
treatment of urological diseases. In addition, each tissue and cellular specimen
received and reviewed by the UroDiagnostics Group is
 
                                       28
<PAGE>
entered into  the database,  and the  Company's contractual  relationships  with
academic  and research centers provide additional specimens. Using the Company's
large and comprehensive database, UroCor's  scientists are able to evaluate  new
technologies  or techniques under  development against samples  in the Company's
database, facilitating determination of  the clinical contribution of  potential
new  products.  The  scientific  research  and  product  development  activities
conducted by the Company's UroSciences Group  constitute a key component of  the
Company's  efforts to  build an  integrated disease  management company  for the
urology market.
 
    The primary  purpose  of the  UroSciences  Group is  to  develop  additional
diagnostic products and technologies for commercialization by the UroDiagnostics
Group.  The  following  table  sets  forth  the  current  principal  development
programs.
<TABLE>
<S>                                       <C>
                              UROSCIENCES DEVELOPMENT PROGRAMS
 
<CAPTION>
 
          DEVELOPMENT PROGRAM                            PROPOSED APPLICATION
- ----------------------------------------  --------------------------------------------------
<S>                                       <C>
 PROSTATE CANCER
  SERUM BASED
    RT-PCR PSA                            Assists in staging and monitoring disease
    Gene discovery                        Enhances cancer-specific detection and monitoring
  TISSUE BASED
    Molecular and antibody markers        Assesses tumor progression and response to therapy
    Computer assisted image analysis      Assesses tumor progression and staging pre-surgery
                                          and predicts progression post-surgery
 
 PROSTATITIS
  URINE BASED
    Microbiological techniques            Differentiates microbial prostatitis
    Molecular markers                     Identifies non-culturable microorganisms
 
 BENIGN PROSTATIC HYPERPLASIA
    Antibody and molecular markers        Selects and monitors medical therapy
    Gene discovery                        Selects and monitors medical therapy
 
 BLADDER CANCER
  URINE BASED -- CELLULAR
    Antibody and molecular markers        Enhances detection, diagnosis and prognosis
    Computer assisted image analysis      Enhances detection, diagnosis and prognosis
  SOLUBLE
    Antibody markers                      Enhances detection, diagnosis and prognosis
 
 INTERSTITIAL CYSTITIS
  URINE BASED -- CELLULAR AND SOLUBLE
    Molecular and antibody markers        Assists in definitive diagnosis and monitors
                                          response to new therapies
</TABLE>
 
    PROSTATE  CANCER.    UroCor  is  developing  a  technology  called   reverse
transcriptase/polymerase  chain  reaction  ("RT-PCR") to  detect  prostate cells
circulating in the blood  which could be relevant  to the metastatic process  in
this  disease.  UroCor  is sponsoring  three  investigational  collaborations to
determine  the   clinical  significance   and  the   potential  for   commercial
applications of the information provided
 
                                       29
<PAGE>
by  this  technology. The  Company  also has  discovered  and is  evaluating the
application of novel genes that are differentially expressed in prostate  cancer
and  benign prostatic hyperplasia ("BPH") that may provide better diagnostic and
prognostic tools.
 
    The UroSciences  Group has  developed computer  assisted image  analysis  of
individual  cancer  cells in  order to  create statistical  models, mathematical
formulae  and  artificial  neural  network  systems  for  facilitating   disease
management  decisions in  prostate and  bladder cancer.  The Company  expects to
develop within the next 18 months commercial applications of this technology for
diagnostic  use   to  improve   the  urologist's   ability  to   determine   the
aggressiveness  of  a patient's  disease and  to  make more  objective treatment
decisions.
 
    PROSTATITIS.  The  Company currently is  developing analytical services  for
the  detection, diagnosis  and monitoring  of acute  and chronic  prostatitis, a
disease characterized by inflammation of the prostate. This disease has  complex
causes and poses difficulties in detection and diagnosis. UroCor is developing a
testing  service planned  for commercial introduction  in 1997 to  assist in the
diagnosis of this disease.
 
    BENIGN PROSTATIC  HYPERPLASIA.   UroCor  is  developing a  product  for  the
diagnosis  of BPH, a prostate disease  that is estimated to affect approximately
50% of all men over age 50. The Company has developed and licensed molecular and
other technologies which it believes  may improve the differential diagnosis  of
BPH  as distinguished  from prostate cancer  and improve the  process of medical
therapy selection.
 
    BLADDER CANCER.   The Company  is developing a  combination of  technologies
which it believes will further enhance its ability to detect early-stage bladder
cancer  and provide the urologist with  diagnostic and prognostic information to
assist in more effective management of  the patient's care. The Company  intends
to  combine specific  biomarkers licensed  from or  supplied by  others with the
Company's computer-assisted image analysis  technology to increase the  accuracy
of the broad range of products the Company presently provides for bladder cancer
management.
 
    INTERSTITIAL  CYSTITIS.  The Company is  developing a product to improve the
diagnosis of  interstitial cystitis,  a debilitating  bladder disorder  that  is
estimated  to affect up  to 450,000 persons in  the United States, approximately
90% of whom are  women. UroCor's product is  directed at providing a  definitive
diagnosis for the disease.
 
    UROTHERAPEUTICS GROUP
 
    UroCor  intends  to  provide  through  its  UroTherapeutics  Group  selected
therapies to urologists for the care  of patients in an office environment.  The
Company   plans  to  license,  acquire   from  others  or  co-market  urological
pharmaceutical products used in the urologist's office and to capitalize on  its
existing specialized sales force to market these products to its existing client
base.  In contrast  to pharmaceutical  companies that  typically market  a broad
range of  products, the  Company intends  to leverage  its focused  approach  by
marketing  therapeutic products  and related  services of  particular benefit to
urologists. The Company also plans to offer ancillary products and services such
as  computerized  order  entry,  just-in-time  inventory,  procedure  trays   to
accompany   therapeutic  interventions,  database  access  and  oncologist  case
consultation as well as reimbursement assistance.
 
    In December  1994,  the  Company  entered into  an  agreement  with  BioVac,
granting exclusive distribution rights in the United States for a strain of BCG,
a  therapeutic  product for  treating certain  types of  bladder cancer.  BCG is
delivered directly into a patient's bladder  by the urologist using a  catheter,
generally  in  an office-based  procedure. The  current BCG  treatment procedure
includes an initial series of six such doses over a six-week period, and  recent
studies  have indicated  that additional maintenance  doses of  BCG delivered at
lengthening intervals may be effective in delaying or eliminating recurrence  of
bladder cancer.
 
    Pursuant  to the distribution agreement, BioVac is responsible for obtaining
approvals from the FDA  for marketing the product  in the United States.  UroCor
may  not commence  selling the  product in  the United  States until  BioVac has
obtained  such  FDA  approval.   In  April  1995,   BioVac  filed  its   initial
 
                                       30
<PAGE>
applications  with the  FDA. BioVac  has informed the  Company that  in a letter
dated  April  18,  1996,  the  FDA  advised  BioVac  that  its  product  license
application is not approvable at this time and that the FDA requested additional
data  regarding certain  aspects of  manufacturing and  testing of  the product.
BioVac  has  advised  the  Company  that  notwithstanding  the  receipt  of  the
non-approvable  letter from the FDA, it believes it can satisfy FDA requirements
and procure approval for marketing the  product in the United States. There  can
be no assurance, however, that such approval will be obtained.
 
    In  the event the BCG product is not  approved by the FDA prior to April 18,
1997, the Company has the right to terminate the distribution agreement. In  the
event  the FDA approves marketing  of the BCG product  in the United States, the
Company's ability to maintain its  exclusive distribution rights is  conditioned
upon meeting certain minimum sales requirements.
 
    In  addition to the  proposed BCG product,  the Company plans  to pursue the
license or acquisition  of other therapeutic  products for distribution  through
its  specialized sales  force. The  Company has no  current plans  to develop or
manufacture therapeutic products.
 
    DISEASE MANAGEMENT INFORMATION SYSTEMS
 
    UroCor believes that useable, relevant information provides one of the  most
important  components  of disease  management services.  The Company  intends to
capitalize on its existing relationships with its urologist clients and  managed
care  organizations and its  existing information resources  to help improve the
clinical management  of  patients  as  well as  its  clients'  productivity  and
profitability.
 
    SECURE  WIDE  AREA NETWORK.   The  Company's Disease  Management Information
Systems group  is developing  a secure  wide area  network that  is intended  to
enhance  two-way communication between UroCor and its physician client base. The
Company  will  initially   focus  application   of  this   network  toward   the
UroDiagnostics  Group. Through this network, a physician will be able to order a
specimen collection kit, send patient and billing information to the Company  in
advance  of  a specimen,  receive advanced  case  reports on  current diagnostic
findings, request a status update for any specimens currently in the  processing
queue  and request a consultation with one of the Company's 11 pathologists. The
Company also intends to develop applications for this network that would  permit
its  clients to  access the  Company's database  as an  educational and practice
management resource.
 
    CLINICAL DECISION  SUPPORT  SYSTEMS.   The  Company is  developing  software
applications  using the UroSciences  Group's database of  thousands of patients'
cellular, tissue and serum  specimens to assist the  urologist in the  prognosis
and  treatment of urological diseases. The  Company initiated development of the
first generation of its proprietary disease pathway computer models for prostate
cancer and  bladder cancer  during  1993. These  models  integrate much  of  the
relevant  published literature on medical practice, technology and various costs
and claims databases to model diagnostic and therapeutic intervention points  in
these  diseases from the detection stage through  the point at which the disease
is either cured or is determined to be incurable.
 
    MANAGEMENT SERVICES.  The Company  believes that two-way computer access  to
its  clients' offices will enhance the  Company's ability to retain its existing
clients and  expand  the  number of  products  and  product types  used  by  its
customers  because of the convenience and  ease of product ordering and transfer
of patient and practice  information. UroCor believes that  this access and  the
Company's  active involvement  in clinical  practice management  present further
opportunities to  assist  the  urologist  with  billing,  collection  and  other
practice management and productivity information processing.
 
COMPETITION
 
    The  market  for providing  urologists and  managed care  organizations with
disease management  systems and  services  is still  emerging, and  the  Company
believes that no other company currently is providing the comprehensive approach
pursued by the Company.
 
    The  market for  providing urologists  with specialized  clinical diagnostic
services  for  detection,   diagnosis,  prognosis  and   monitoring  is   highly
competitive  and  fragmented.  The majority  of  this  market is  served  by the
hundreds of local free-standing or hospital-pathology services for the  cellular
and tissue
 
                                       31
<PAGE>
diagnostic  services offered  by the  Company, and  other hospital laboratories,
specialty laboratories and  general reference laboratories  provide some of  the
serum  testing provided by the Company.  The main competitive advantage of local
hospital  pathology  service  providers  is  long-established  local   physician
referral  practices.  The general  reference laboratories'  competitive strength
lies in their service capabilities to provide local couriers for specimen pickup
and broad-based  contracting  ability  with managed  care  organizations.  Other
companies  that already market diagnostic products and medical supplies in other
fields  have  begun  marketing  kits  for  detecting  certain  cancers  in   the
urologist's  office. The Company believes  that it will be  able to compete with
these diagnostic service providers because  of its disease management  approach,
its broad range of diagnostic products and services, its urology-dedicated sales
force and its focused product research and development efforts.
 
    In the therapeutics segment of the urology market, both surgery performed by
the  urologists and  a number  of chemotherapeutic  drugs will  compete with the
Company's proposed BCG therapy product  for bladder cancer. Two other  companies
Connaught  Laboratories,  Inc.  and  Organon, Inc.,  already  are  marketing BCG
products  in  the  United  States.  Many  major  and  mid-sized  pharmaceuticals
companies   which  can  deploy  larger  sales  organizations  and  research  and
development efforts compete for sales of other urological drugs. Because of  its
existing  relationships  with urologists  through  its UroDiagnostics  Group and
existing specialized sales force, the Company  believes that it has the  ability
to compete in this market.
 
    Information  systems companies  provide software products  that will compete
with proposed Company products that enable a urologist to store patient  records
and  practice information. In addition, other companies are building regional or
national databases focused on improving  clinical and economic disease  outcomes
similar  to the  Company's application of  its urological  disease database. The
main competitive advantage of  these companies is their  knowledge and focus  on
software  and  system development.  Many  of these  companies  have considerably
greater resources and experience than the Company in the development of software
and information systems, and could gain effective access to the urologists.  The
Company  believes that the  principal competitive factors  for clinical outcomes
database software are the quality and depth of the underlying clinical  outcomes
database,  the usefulness  of the  data and  reports generated  by the software,
customer service  and support,  ease-of-use, compatibility  with the  customer's
existing  information systems,  potential for  product enhancements,  and vendor
reputation. The Company believes that its  ability to compete in this area  lies
in its expertise and focus on urology.
 
    The  Company also competes with  many biotechnology companies, manufacturers
of diagnostic systems and  kits as well as  other producers and distributors  of
medical  products for  the acquisition  of technology  for research  and product
development. The Company believes its own product and technology development and
evaluation capabilities together with its  expertise in urological diseases  and
market access provide it with the ability to compete successfully in this area.
 
    Many  of  the  Company's  competitors  are  significantly  larger  and  have
significantly greater financial, technical and administrative resources than the
Company. Many  also  have  long-established  relationships  with  the  Company's
current and prospective customers. See "Risk Factors -- Competition".
 
GOVERNMENT REGULATION
 
    The  health care industry in  the United States is  highly regulated and the
diagnostic service segment, which  includes the Company's UroDiagnostics  Group,
is  no exception. The  Company's diagnostic laboratory  operations currently are
not regulated by the FDA. While the FDA  now indicates that it does not plan  to
regulate  assays developed by laboratories for in-house use, the FDA in the past
has drafted guidelines for regulation of such  assays. If in the future the  FDA
were  to  issue  guidelines  for the  clinical  laboratory  market  sector, such
guidelines might require the Company to meet certain FDA medical device approval
requirements for the Company's in-house assays. The FDA currently regulates some
of the tests and systems purchased by the Company from third parties and used in
the Company's  diagnostics  business. The  manufacturers  of such  products  are
responsible  for compliance with  the approval and  marketing regulations of the
FDA.   If    the   UroSciences    Group   should    decide   to    market    any
 
                                       32
<PAGE>
of its diagnostic technology as test kits to be used by third parties, such test
kits  would  require  FDA  approval.  The  Company  performs  extensive internal
validation procedures and selected independent clinical trials on new tests  and
markers  which it intends  to market. While  no assurances may  be given in such
regard, the Company believes that it  could adjust to any reasonable changes  in
applicable  FDA requirements without significant disruption or financial impact.
In the event that  any such changes are  more extensive than anticipated,  these
changes  would increase  the cost of  development and approval  of new products,
slow their introduction to the market  and could have a material adverse  effect
on the Company's financial condition and results of operations.
 
    The  Company's  business  is  also  subject  to  a  variety  of governmental
regulations at  the federal,  state  and local  levels. The  Company's  clinical
laboratory  is  certified  under  the federal  Medicare  program,  certain state
Medicaid programs and  CLIA. The  Company also  is licensed  under the  clinical
laboratory  licensure laws of Oklahoma,  where the Company's clinical laboratory
is located. Since  the Company  provides clinical testing  services to  patients
nationwide,  its laboratory is  also licensed under  the laws of  those state or
local governments which the Company is aware have clinical laboratory regulation
programs applicable to  out-of-state laboratories. The  Company believes it  has
obtained all such licenses required for its operations.
 
    In  addition,  certain  regulatory authorities  require  participation  in a
proficiency testing program approved by  the United States Department of  Health
and  Human Service ("DHHS")  for each of the  specialties and subspecialties for
which a laboratory seeks approval from Medicare or Medicaid and licensure  under
CLIA. Proficiency testing programs involve actual testing of specimens that have
been  prepared  by an  entity running  an  approved program  for testing  by the
laboratory. The Company believes  it is in compliance  in all material  respects
with all such applicable regulations.
 
    The  federal Social  Security Act  imposes criminal  penalties and exclusion
from the Medicare program upon persons who make or receive kickbacks, bribes  or
rebates  in  connection  with  the  Medicare  program.  The  anti-kickback rules
prohibit providers and  others from soliciting,  offering, receiving or  paying,
directly  or indirectly, any remuneration in return for either making a referral
for a Medicare-covered service or item  or ordering any such covered service  or
item.  Because the Medicare  and certain related  state anti-kickback rules have
been broadly  interpreted, they  could limit  the manner  in which  the  Company
conducts  its business. The Company believes that it currently complies with the
anti-kickback rules  in its  activities.  No assurance  can be  given,  however,
regarding  compliance in any particular factual situation, as there is currently
no procedure for advisory opinions from government officials.
 
    Under another  provision,  known  as  the  "Stark"  law  or  "self-referral"
prohibition, physicians who have an investment or compensation relationship with
an entity furnishing clinical laboratory services (including pathology services)
may  not, subject to certain exceptions,  refer clinical laboratory analyses for
Medicare patients to that entity. Similarly, facilities may not bill Medicare or
any other  party  for services  furnished  pursuant to  a  prohibited  referral.
Violation  of these provisions may result in disallowance of Medicare claims for
the affected analysis  services, as  well as  the imposition  of civil  monetary
penalties  and program  exclusion. A  number of  states, including  New York and
California,  have  enacted  similar  prohibitions  to  the  Stark  law  covering
referrals  of non-Medicare as  well as Medicare business.  These state rules are
very restrictive,  prohibit  submission of  claims  for payment  for  prohibited
referrals  and  provide  for  the  imposition  of  civil  monetary  and criminal
penalties. The Company believes it has  no prohibited relationships with any  of
its  referrers, however, the Company is unable  to predict how these laws may be
applied in the future, or whether the federal government or states in which  the
Company  operates will enact  more restrictive legislation  or restrictions that
could affect the Company's operations under certain circumstances.
 
    Any exclusion or suspension from participation in the Medicare program,  any
loss  of  licensure or  accreditation or  any inability  to obtain  any required
license or permit, whether arising from any action
 
                                       33
<PAGE>
by DHHS, any  state or  any other regulatory  authority, would  have a  material
adverse  effect on  the Company's  business. Any  significant civil  monetary or
criminal penalty resulting from such  proceedings could have a material  adverse
effect on the Company's financial condition and results of operations.
 
    The  laws of many states prohibit  physicians from sharing professional fees
with non-physicians and  prohibit non-physician entities,  such as the  Company,
from  practicing medicine (including pathology) and from employing physicians to
practice medicine (including pathology). The  laws in most states regarding  the
corporate  practice  of medicine  have been  subjected  to limited  judicial and
regulatory  interpretation.  The  Company  believes  its  current  and   planned
activities do not constitute prohibited fee splitting or violate any prohibition
against  the corporate practice of medicine. There can be no assurance, however,
that future  interpretations  of  such  laws  will  not  require  structural  or
organizational modifications of the Company's existing business.
 
    Pursuant  to the  federal Occupational  Safety and  Health Act, laboratories
have a general duty  to provide a  work place for their  employees that is  safe
from  hazard. The  United States  Occupational Safety  and Health Administration
("OSHA") has issued  rules relevant  to certain hazards  that are  found in  the
laboratory. In addition, OSHA issued a standard in 1992 applicable to protection
of  workers from  blood-borne pathogens.  Failure to  comply with  this standard
relating to  blood-borne pathogens,  other  applicable OSHA  rules or  with  the
general duty to provide a safe work place could subject an employer, including a
laboratory employer such as the Company, to substantial fines and penalties.
 
THIRD-PARTY REIMBURSEMENT
 
    In 1993, 1994, 1995 and the first three months of 1996, the Company received
approximately  56%, 58%, 58% and 53%, respectively, of its revenue from services
performed principally for beneficiaries of  the Medicare program. Under law  and
regulation,  for most of the services  performed for Medicare beneficiaries, the
Company must accept reimbursement from Medicare  as payment in full, subject  to
applicable  co-payments and deductibles. In 1987,  1989 and 1990, federal budget
legislation  instituted  changes   in  Medicare's  fee   schedule  relating   to
reimbursement  for  laboratory  services.  Each  such  change  lowered  Medicare
reimbursement schedules. Other  legislative proposals have  been made which,  if
enacted, could have an adverse effect on reimbursement of laboratory services.
 
    Reimbursement rates for most of the Company's services have been established
by  Medicare and some third-party  payors, but have not  been established by all
insurance carriers. Although substantially all of the Company's current services
receive reimbursement at various rates or  on a case-by-case basis, some of  the
services  that the  Company may  provide in  the future  may not  be approved by
Medicare or  some  other third-party  payors  and reimbursement  rates  on  such
services  cannot be predicted.  The Company cannot collect  from Medicare or any
other third-party payor  for services  not approved by  them for  reimbursement.
Approval by Medicare or other federal agencies does not assure approval by other
third-party   payors.  Most  third-party  payors,  including  Medicare,  do  not
reimburse for services that they  determine to be experimental,  investigational
or  otherwise not reasonable and necessary  for diagnosis or treatment. A formal
coverage determination  is made,  however, with  respect to  relatively few  new
procedures.  When such determinations do occur  for Medicare purposes, they most
commonly are  made by  the local  Medicare carrier  which processes  claims  for
reimbursement  within the carrier's geographic  jurisdiction. Medicare may audit
and review its prior payments to the Company, and may determine that certain  of
those payments must be refunded.
 
INTELLECTUAL PROPERTY
 
    The  Company  has  completed  numerous license  and  option  agreements with
academic centers and biotechnology  companies covering technologies it  believes
may be of utility in the future in improving urological disease management. Most
of  these arrangements provide the Company exclusive commercial rights worldwide
in all human  diagnostics and several  also provide the  option for  therapeutic
applications.
 
    The   Company  licenses  patents  and  seeks  patents  when  appropriate  on
inventions concerning  new products  and  improvements as  part of  its  ongoing
research, development and marketing efforts. While
 
                                       34
<PAGE>
the  Company believes these technologies  and particularly any patent protection
which may  become available  should  help the  Company improve  its  competitive
position  in its  market, the  Company presently  is not  dependent on  any such
patents and does not expect to become dependent on patents in the future.
 
    The Company attempts to protect its proprietary products by relying on trade
secrets and  on  non-disclosure  and  confidentiality  agreements.  The  Company
requires  its  employees,  consultants,  outside  scientific  collaborators  and
sponsored researchers and other  advisors to execute confidentiality  agreements
upon  the  commencement  of  employment  or  consulting  relationships  with the
Company. These agreements  generally provide that  all confidential  information
developed or made known to the individual during the course of the relationships
is  to be kept confidential  and not to be disclosed  to third parties except in
specific circumstances. In the  case of employees,  the agreements provide  that
any  inventions  conceived by  the individual  within  the scope  of his  or her
employment shall  be the  exclusive property  of the  Company. There  can be  no
assurance, however, that these agreements will provide meaningful protection for
any  of  the  Company's  trade  secrets in  the  event  of  unauthorized  use or
disclosure of such information.
 
    The Company intends to  seek copyright protection  when appropriate for  any
information systems products it may develop.
 
    The  Company has  registered the service  marks UROCOR-Registered Trademark-
and UROSCORE-Registered Trademark- with the  United States Patent and  Trademark
Office.
 
ENVIRONMENTAL MATTERS
 
    The  Company is  subject to federal,  state and local  laws, regulations and
policies governing  the use,  generation,  manufacture, storage,  air  emission,
effluent  discharge,  handling  and disposal  of  certain  materials, biological
specimens and wastes. Although the Company believes that it has complied in  all
material  respects with  these laws, regulations  and policies and  has not been
required to  take any  action to  correct  any noncompliance,  there can  be  no
assurance  that the Company will  not be required to  incur significant costs to
comply with environmental and health and safety regulations in the future.
 
    The Company's research and development activities involve the controlled use
of hazardous  materials, including  certain hazardous  chemicals and  infectious
biological  specimens. Although the Company  believes that its safety procedures
for  handling  and  disposing  of  such  materials  comply  with  the  standards
prescribed   by  state   and  federal   regulations,  the   risk  of  accidental
contamination or injury from these materials cannot be eliminated. In the  event
of  such an  accident, the  Company could  be held  liable for  any damages that
result and any such liability could exceed the resources of the Company.
 
EMPLOYEES
 
    At May 1, 1996, the Company had 208 full-time and 37 part-time employees, of
which 89 were  employed in  diagnostic services  operations and  support, 94  in
sales and marketing, 23 in research and development and 39 in administration and
accounting.  At May 1,  1996, the Company  employed, full time,  11 persons with
M.D. degrees and six persons with  Ph.D. degrees. The Company believes that  its
relationship with its employees is good.
 
FACILITIES AND OPERATIONS
 
    The Company leases approximately 48,000 square feet of administration, sales
and  marketing, operations and research and  development space in Oklahoma City,
Oklahoma. The Company's  initial lease term  expires in June  2005 which may  be
extended  at the Company's option for an  additional five years. The Company has
rights of first refusal  to lease additional  space in the  rest of the  110,000
square foot building as well as a purchase option on the building. The Company's
monthly rental obligation for its facilities currently is approximately $32,000.
The  Company believes  that its leased  facilities are adequate  for its current
needs and that suitable, additional space will be available on acceptable  terms
for the foreseeable future.
 
                                       35
<PAGE>
                                   MANAGEMENT
 
DIRECTORS, EXECUTIVE OFFICERS AND KEY EMPLOYEES
 
    The  following table sets forth information as of May 1, 1996, regarding the
executive officers, directors and certain key employees of the Company.
 
<TABLE>
<CAPTION>
NAME                                     AGE      POSITION
- -----------------------------------      ---      -------------------------------------------------
<S>                                  <C>          <C>
William A. Hagstrom................      38       Chairman of the Board, President and
                                                  Chief Executive Officer
Socrates H. Choumbakos.............      51       Vice President, Corporate Development,
                                                  Chief Financial Officer and Secretary
Mark G. Dimitroff..................      49       Vice President and General Manager UroDiagnostics
                                                  Group
Robert W. Veltri, Ph.D.............      54       Vice President and General Manager UroSciences
                                                  Group
Kathryn L. W. Ingerly..............      37       Vice President Disease Management Information
                                                  Systems
Gerard J. O'Dowd, M.D..............      45       Medical Director
Michael N. McDonald................      38       Director of Finance and Administration,
                                                  Treasurer and Assistant Secretary
Paul A. Brown, M.D.(1)(2)..........      58       Director
Herbert J. Conrad(2)...............      63       Director
Michael E. Herbert(1)..............      51       Director
Louis M. Sherwood, M.D.............      59       Director
Don E. Spyrison....................      50       Director
Joe D. Tippens(2)..................      38       Director
</TABLE>
 
- --------------------------
(1) Member of Compensation Committee.
 
(2) Member of Audit Committee.
 
    WILLIAM A. HAGSTROM.  Mr.  Hagstrom has been a  director of the Company  and
served  as President and  Chief Executive Officer of  the Company since November
1989. Mr. Hagstrom was appointed Chairman of the Board of Directors in September
1994. Before  joining  the Company,  Mr.  Hagstrom  was Vice  President  of  the
Scientific  Products Division  of Baxter-Travenol,  a medical  products company,
where he  served  in various  marketing,  sales, product  planning  and  general
management  positions  from November  1985 to  November  1989. Prior  to joining
Baxter-Travenol, he spent three years at American Hospital Supply Corp. until it
was acquired by  Baxter-Travenol and three  years at Becton  Dickinson & Co.  in
various management positions.
 
    SOCRATES  H. CHOUMBAKOS.  Mr. Choumbakos joined  the Company in June 1992 as
Vice President, Corporate  Development, Chief Financial  Officer and  Secretary.
Before  joining the Company, Mr. Choumbakos was President of Venture Development
Group, a corporate and business development consulting firm, from March 1988  to
June  1992.  From March  1988 to  December  1990, Mr.  Choumbakos was  also Vice
President and Chief Financial Officer  of Creative Business Strategies, Inc.,  a
business  development  consulting  firm. From  August  1979 to  March  1988, Mr.
Choumbakos was Director of  Corporate Development at Becton  Dickinson & Co.,  a
medical  products company.  Prior to  1979, he was  a Senior  Manager with Price
Waterhouse & Co. where he worked for 13 years.
 
    MARK G. DIMITROFF.   Mr. Dimitroff joined  the Company in  May 1990 as  Vice
President,  Marketing and  Sales and became  Vice President  and General Manager
UroDiagnostics Group in October 1994. Before joining the Company, Mr.  Dimitroff
served  as  Vice President,  Marketing and  Sales for  Dianon Systems,  Inc., an
oncology specialty reference laboratory, from 1984  to May 1990. Prior to  1984,
he  held senior  marketing and sales  management positions with  MetPath Inc., a
large general reference laboratory, and American Hospital Supply Corp.
 
                                       36
<PAGE>
    ROBERT W. VELTRI, PH.D.   Dr. Veltri joined the  Company in October 1990  as
Vice President, Product Planning and Technology Development and Chief Scientific
Officer,  and became  Vice President  and General  Manager UroSciences  Group in
October 1994. Before  joining the  Company, Dr.  Veltri was  the Executive  Vice
President  and  Chief  Technical  Officer  at  Theracel,  Inc.,  a  therapeutics
development company, from 1988  to October 1990. From  1984 to 1988, Dr.  Veltri
was   a  founder  and   President  and  Chief   Executive  Officer  of  American
Biotechnology Company,  the predecessor  to Theracel,  Inc. Prior  to 1984,  Dr.
Veltri  was Director of Research and Development for the Immunology Group (rapid
IN VITRO diagnostic test  development) at Cooper  Biomedical Inc., a  diagnostic
products  company, and  was Professor of  Microbiology and  Surgery, Director of
Research in Otolaryngology and Supervisor of the Special Immunology and Virology
Clinical Laboratory at West Virginia University Medical School for 13 years.
 
    KATHRYN L. W. INGERLY.  Ms. Ingerly joined the Company in April 1996 as Vice
President, Disease Management Information  Systems. Before joining the  Company,
Ms.  Ingerly was the  President and Chief Executive  Officer of Ingerly Alliance
Partners, L.L.C.,  an information  technology consulting  company since  January
1995.  From  September  1988 through  December  1994, Ms.  Ingerly  held various
positions with Market Investment Solutions, a software development and  services
company,  most recently as President and Chief Executive Officer. Prior to 1988,
Ms. Ingerly was the Financial and Systems Manager of the Cleo Wallace Center,  a
regional health care provider in Denver, Colorado.
 
    GERARD  J. O'DOWD,  M.D.  Dr.  O'Dowd joined  the Company in  August 1990 as
Medical Director. Before joining the Company, Dr. O'Dowd was in private practice
specializing in fine needle aspiration cytology and served as a pathologist  for
a  regional reference laboratory in the  Washington, D.C. area from January 1988
to August 1990. From 1983  to December 1987, Dr. O'Dowd  served on the staff  of
George Washington Medical Center where he was Chief Pathologist for the Division
of  Cytopathology  and  Hematopathology.  He received  his  medical  degree from
Georgetown University School of Medicine, completed a pathology residency at the
University of Utah  and was  a Cytopathology Fellow  at the  Medical College  of
Virginia.
 
    MICHAEL  N.  MCDONALD.   Mr. McDonald  joined  the Company  in June  1992 as
Controller  and  Assistant  Secretary  and   became  Director  of  Finance   and
Administration  and Treasurer in  October 1994. Before  joining the Company, Mr.
McDonald was a Manager in the  Accounting and Audit Division at Arthur  Andersen
LLP where he served in various capacities from December 1980 to June 1992.
 
    PAUL  A. BROWN, M.D.  Dr. Brown has  been a director since November 1988. He
has been Chairman  of the Board  and Chief  Executive Officer of  HeaRx Ltd.,  a
medical products and services company, for the past six years. Prior to founding
HeaRx, Dr. Brown was founder and Chairman of the Board of MetPath Inc. Dr. Brown
is  currently on the Board of Trustees of Tufts University, past Chairman of the
Board of Overseers of the Tufts University  School of Medicine, a member of  the
visiting  committee  of Boston  University School  of  Medicine and  a part-time
member of the Columbia University College of Physicians and Surgeons.
 
    HERBERT J. CONRAD.  Mr. Conrad has been a director since October 1993. Until
his retirement in August 1993, Mr. Conrad  served for more than five years as  a
senior  executive with  Hoffmann-LaRoche, Inc.,  a pharmaceutical  company, most
recently  as  a   director,  Senior   Vice  President  and   President  of   the
Pharmaceuticals Division. Mr. Conrad has more than 30 years of experience in the
pharmaceutical  industry, primarily with Hoffmann-LaRoche, where he held several
senior management positions  in marketing, business  and strategic planning  and
public   affairs.  Mr.  Conrad  has  also   served  as  a  director  of  several
pharmaceutical-related companies, including Dura Pharmaceuticals,  Biotechnology
General and Bradley Pharmaceuticals.
 
    MICHAEL  E. HERBERT.  Mr.  Herbert has been a  director since July 1994. Mr.
Herbert has served  for more than  five years as  President and Chief  Executive
Officer  of Physicians Health Services, Inc., an individual practice association
health maintenance organization ("IPA/HMO")  serving members in Connecticut  and
New  York.  Under  Mr.  Herbert's  direction,  Physicians  Health  Services  has
developed over the past  19 years into New  England's first federally  qualified
IPA/HMO. Prior to joining Physicians
 
                                       37
<PAGE>
Health Services, Mr. Herbert was Vice President of InterStudy, a national health
policy  research firm  focusing on  a marketplace  approach to  health care. Mr.
Herbert is the past Chairman of the American Managed Care and Review Association
and was Charter President of the Association of Connecticut HMOs.
 
    LOUIS M. SHERWOOD,  M.D.   Dr. Sherwood has  been a  director since  October
1993.  Since 1987, Dr. Sherwood has been Senior Vice President, U.S. Medical and
Scientific Affairs,  of Merck  &  Co., a  pharmaceutical company.  His  academic
appointments  include seven  years as Baumritter  Professor and  Chairman of the
Department of  Medicine at  Albert Einstein  College of  Medicine, Professor  of
Biochemistry and Physician in Chief at Montefiore Medical Center, eight years as
Chairman  of  Medicine at  the  Michael Reese  Medical  Center and  Professor of
Medicine at the University of Chicago. He also served as Chief of  Endocrinology
at  Beth Israel Hospital and Assistant  Professor of Medicine at Harvard Medical
School.
 
    DON E. SPYRISON.  Mr. Spyrison has been a director since November 1989. From
October 1988 to November 1989, he served as President, and from November 1990 to
September 1994, he  served as Chairman  of the  Board. Mr. Spyrison  has been  a
general  partner of The Woodlands Venture Partners, L.P., the general partner of
The Woodlands  Venture  Fund, L.P.,  a  venture  capital firm  and  a  principal
stockholder  of the Company, since November  1988. Since September 1994, he also
has served as special limited  partner of the Woodlands-Essex Venture  Partners,
L.P., a venture capital firm. Since September 1995, he has been serving as Chief
Executive  Officer and director  of Protocol Work  Systems, Inc., an information
systems company. Mr. Spyrison was a  director and President and Chief  Executive
Officer  of Optex Biomedical, Inc., a medical device company, from April 1992 to
December 1995, at  which time  Optex filed  for relief  under Chapter  7 of  the
federal bankruptcy laws.
 
    JOE D. TIPPENS.  Mr. Tippens has been a director since May 1991. Mr. Tippens
has  been President  and Managing Director  of Chisolm Private  Capital, Inc., a
venture capital  firm, since  May 1994  and  also serves  as consultant  to  the
management  company  to ML  Oklahoma  Venture Partners,  Limited  Partnership, a
venture capital firm and a principal  stockholder of the Company. From  November
1988  until May 1994, Mr. Tippens was  a Vice President of Merrill Lynch Venture
Capital Inc., a  venture capital firm  and an affiliate  of ML Oklahoma  Venture
Partners,  Limited  Partnership. From  1983 through  November 1988,  Mr. Tippens
worked privately in the venture capital industry. Prior to 1983, Mr. Tippens was
a Manager  in the  Audit  Division of  Arthur Andersen  LLP.  Mr. Tippens  is  a
director of Silverado Foods, Inc., a food products distribution company.
 
CLASSIFIED BOARD
 
    The Restated Certificate of Incorporation provides for the classification of
the  Board of Directors into  three classes of directors  (Class I, Class II and
Class  III),  with  the  term  of  each  class  expiring  at  successive  annual
stockholders'  meetings. At and  after the 1997  Annual Meeting of Stockholders,
all nominees of the class standing  for election will be elected for  three-year
terms.  The terms of office for Messrs.  Spyrison and Tippens expire at the 1997
Annual Meeting  of Stockholders,  the terms  of  office of  Mr. Conrad  and  Dr.
Sherwood  expire at the  1998 Annual Meeting  of Stockholders, and  the terms of
office of Dr.  Brown, Mr. Herbert  and Mr.  Hagstrom expire at  the 1999  Annual
Meeting of Stockholders.
 
COMMITTEES
 
    The Board of Directors of the Company has established an Audit Committee and
a  Compensation Committee. The  Audit Committee is  charged with recommending to
the Board of Directors  the appointment of  the Company's independent  auditors,
reviewing  the compensation of such auditors and reviewing with such accountants
the plans  for and  the results  and  scope of  their auditing  engagement.  The
Compensation  Committee reviews  the performance and  compensation of directors,
executive officers and key employees and  makes recommendations to the Board  of
Directors  with respect thereto. The Compensation Committee also administers the
Company's Amended and Restated  1992 Stock Option Plan  (the "1992 Stock  Option
Plan").
 
                                       38
<PAGE>
COMPENSATION OF EXECUTIVE OFFICERS
 
    COMPENSATION
 
    The  following table sets forth all compensation  paid by the Company to its
Chief Executive Officer and each of its executive officers as to whom the  total
annual salary and bonus for the year ended December 31, 1995, exceeded $100,000.
 
                           SUMMARY COMPENSATION TABLE
 
<TABLE>
<CAPTION>
                                                                                                        LONG-TERM
                                                                                                      COMPENSATION
                                                                               ANNUAL COMPENSATION   ---------------
                                                                                                       SECURITIES
                                                                               --------------------    UNDERLYING
NAME AND PRINCIPAL POSITION                                                     SALARY      BONUS      OPTIONS(1)
- -----------------------------------------------------------------------------  ---------  ---------  ---------------
<S>                                                                            <C>        <C>        <C>
William A. Hagstrom
 Chairman of the Board, President and Chief Executive Officer................  $ 160,202  $  31,522        60,000
Socrates H. Choumbakos
 Vice President, Corporate Development, Chief Financial Officer and
 Secretary...................................................................    129,585     15,700        30,000
Mark G. Dimitroff
 Vice President and General Manager UroDiagnostics Group.....................    129,909     18,435        40,000
Robert W. Veltri, Ph.D.
 Vice President and General Manager UroSciences Group........................    126,404     15,431        30,000
</TABLE>
 
- ------------------------------
(1)  Represents shares issuable pursuant to options granted under the 1992 Stock
     Option Plan.
 
    The  following table sets forth  information concerning individual grants of
stock options made  during the  year ended  December 31,  1995, to  each of  the
executive officers named in the Summary Compensation Table.
 
              OPTION GRANTS IN FISCAL YEAR ENDED DECEMBER 31, 1995
 
<TABLE>
<CAPTION>
                                                          INDIVIDUAL GRANTS                       POTENTIAL REALIZABLE
                                      ----------------------------------------------------------    VALUE AT ASSUMED
                                        NUMBER OF                                                 ANNUAL RATES OF STOCK
                                       SECURITIES      % OF TOTAL                                  PRICE APPRECIATION
                                       UNDERLYING    OPTIONS GRANTED   EXERCISE OR                 FOR OPTION TERM(2)
                                         OPTIONS     TO EMPLOYEES IN   BASE PRICE    EXPIRATION   ---------------------
NAME                                   GRANTED(1)         1995          PER SHARE       DATE         5%         10%
- ------------------------------------  -------------  ---------------  -------------  -----------  ---------  ----------
<S>                                   <C>            <C>              <C>            <C>          <C>        <C>
William A. Hagstrom.................       60,000            14.9%      $    1.75      12/15/05   $ 774,600  $1,295,400
Socrates H. Choumbakos..............       30,000             7.4            1.75      12/15/05     387,300     647,700
Mark G. Dimitroff...................       40,000             9.9            1.75      12/15/05     516,400     863,600
Robert W. Veltri, Ph.D..............       30,000             7.4            1.75      12/15/05     387,300     647,700
</TABLE>
 
- ------------------------------
(1)  Represents shares issuable pursuant to options granted under the 1992 Stock
     Option Plan. Options vest 33 1/3% annually beginning December 29, 1996.
 
(2)  Future  value of grants assuming appreciation in market value of the Common
     Stock of 5% and 10% over the ten-year term of the options. The actual value
     realized may be greater  or less than the  potential realizable values  set
     forth in the table. Solely for purposes of determining the value of options
     at December 31, 1995, the Company has assumed that the fair market value of
     the Common Stock issuable upon exercise of options was $9.00 per share, the
     assumed  initial  public offering  price, since  the  Common Stock  was not
     traded in an established market prior to the Offering.
 
                                       39
<PAGE>
    None of  the executive  officers  named in  the Summary  Compensation  Table
exercised options in 1995. The following table sets forth information concerning
the value of unexercised options held by such persons at December 31, 1995.
 
                       OPTION VALUES AT DECEMBER 31, 1995
 
<TABLE>
<CAPTION>
                                                                  NUMBER OF
                                                            SECURITIES UNDERLYING        VALUE OF UNEXERCISED
                                                             UNEXERCISED OPTIONS        IN-THE-MONEY OPTIONS AT
                                                            AT DECEMBER 31, 1995         DECEMBER 31, 1995(1)
                                                         ---------------------------  ---------------------------
NAME                                                     EXERCISABLE  UNEXERCISABLE   EXERCISABLE  UNEXERCISABLE
- -------------------------------------------------------  -----------  --------------  -----------  --------------
<S>                                                      <C>          <C>             <C>          <C>
William A. Hagstrom....................................      63,987        102,659     $ 527,893    $    786,937
Socrates H. Choumbakos.................................      75,080         42,120       646,210         317,490
Mark G. Dimitroff......................................      19,690         53,128       162,443         398,306
Robert W. Veltri, Ph.D.................................      26,580         47,720       219,285         363,690
</TABLE>
 
- --------------------------
(1) The dollar values have been calculated by determining the difference between
    the  fair market value of the  securities underlying the options at December
    31, 1995, and  the exercise prices  of the options.  Solely for purposes  of
    determining  the  value of  options at  December 31,  1995, the  Company has
    assumed that  the  fair market  value  of  the Common  Stock  issuable  upon
    exercise of options was $9.00 per share, the assumed initial public offering
    price,  since the Common Stock was not traded in an established market prior
    to the Offering.
 
    EMPLOYMENT AGREEMENTS
 
    Mr. Hagstrom  entered  into an  employment  agreement with  the  Company  in
January  1990.  Under  the  terms  of such  agreement,  Mr.  Hagstrom  serves as
President and Chief  Executive Officer.  The term of  the agreement  is for  one
year,  with  automatic  renewals indefinitely  for  further  successive one-year
periods unless  terminated  by  either  party. The  Company  may  terminate  the
agreement  upon Mr. Hagstrom's death or disability or for cause (as that term is
defined therein). The Company  may terminate the agreement  at any time  without
cause,  provided that  the Company  continues to  pay Mr.  Hagstrom at  his then
current base  salary rate,  on a  monthly basis,  for six  months following  the
effective  date  of termination.  Pursuant to  the terms  of the  agreement, the
Company may pay Mr. Hagstrom bonuses in  such amounts as the Board of  Directors
in its sole discretion may determine.
 
    Messrs.  Choumbakos  and Dimitroff,  Dr. Veltri  and  Ms. Ingerly  each have
entered into agreements with the Company regarding the respective terms of their
employment. None of such agreements provide for fixed periods of employment. The
agreement with Mr. Choumbakos  provides for a current  base salary of  $134,820,
subject  to annual review, a bonus of up to  25% of his annual base salary and a
severance obligation of six months upon termination without cause. The agreement
with Mr. Dimitroff provides  for a current base  salary of $140,075, subject  to
annual  review, and a  bonus of up  to 30% of  his annual base  salary. In April
1996, the Company's Board of Directors  approved a severance obligation for  Mr.
Dimitroff  of  six  months upon  termination  of employment  without  cause. The
agreement with  Dr. Veltri  provides  for a  current  base salary  of  $134,724,
subject  to annual review, a bonus of up to  25% of his annual base salary and a
severance obligation of three  months upon termination  without cause. In  April
1996,  the Company's  Board of  Directors approved  an increase  in Dr. Veltri's
bonus to up to 30%  of his annual base salary  and an increase in his  severance
obligation  to  six months  upon termination  of  employment without  cause. The
agreement with  Ms. Ingerly  provides for  a current  base salary  of  $120,000,
subject  to annual review, a bonus of up to  30% of her annual base salary and a
severance obligation of three months upon termination without cause.
 
    BONUS PLAN
 
    In 1991, the Company established a management incentive compensation program
under which most full-time employees, including executive officers, are eligible
to receive cash  bonuses, subject  to the  Company achieving  certain sales  and
operating  income  levels  as  well  as  achievement  of  individual performance
criteria. Bonus  levels are  established  for each  individual, ranging  from  a
minimum of up to $1,000 per employee to a maximum of up to 40% of annual salary.
In  February 1993, the  Company paid $172,230  under the plan  for the 1992 plan
year, of which an aggregate of $102,254 was paid to the four executive  officers
named  in the Summary Compensation  Table. In March and  April 1994, the Company
 
                                       40
<PAGE>
paid a total  of $279,863 under  the plan for  the 1993 plan  year, of which  an
aggregate  of $119,539 was paid  to the four named  executive officers. In April
1995, the Company  paid a total  of $251,932 under  the plan for  the 1994  plan
year,  of which  an aggregate of  $81,088 was  paid to the  four named executive
officers. In April 1996, the Company paid a total of $399,529 under the plan for
the 1995 year,  of which an  aggregate of $100,157  was paid to  the four  named
executive officers.
 
COMPENSATION OF DIRECTORS
 
    Each  director receives reimbursement for  expenses related to attendance at
Board meetings. Mr. Conrad, Mr. Herbert and Dr. Sherwood each receive $1,500 for
each meeting of the Board of Directors attended.
 
1992 STOCK OPTION PLAN
 
    The Company's 1992  Stock Option  Plan is administered  by the  Compensation
Committee of the Board of Directors. Pursuant to the plan, options to acquire an
aggregate  of 1,400,000 shares of Common Stock may be granted to individuals who
are  employees,  officers,  directors  or  independent  contractors   performing
services  for the  Company. As  of May 10,  1996, options  to purchase 1,001,594
shares of Common Stock were outstanding and 315,519 shares remained reserved for
grants of options under the plan.
 
    The 1992  Stock Option  Plan  authorizes the  Board  of Directors  to  issue
options  intended to qualify as incentive  stock options ("ISOs"), as defined in
Section 422A of the Internal Revenue Code of 1986, as amended (the "Code"),  and
stock  options that are not intended to conform to the requirements of such Code
section ("non-qualified options").  The exercise price  of each ISO  may not  be
less  than the fair market value of the  Common Stock at the time of grant, and,
in the case of a grant  to an employee who owns  10% or more of the  outstanding
voting stock of the Company (a "10% Stockholder"), the exercise price may not be
less than 110% of the fair market value on the date of grant. The exercise price
of  each non-qualified option  granted under the  plan may not  be less than the
fair market value  of the Common  Stock on  the date of  grant. Options  granted
under  the plan may not  be exercised after the  tenth anniversary (or the fifth
anniversary in the  case of an  option granted  to a 10%  Stockholder) of  their
grant.
 
                              CERTAIN TRANSACTIONS
 
    The  Company paid consulting  fees to Dr.  Paul A. Brown,  a director of the
Company, for consultation  on business and  scientific matters totaling  $36,000
for each of 1993, 1994 and 1995.
 
    In  October 1993, in connection with  the private placement of approximately
$1.0 million aggregate principal amount of 8% convertible promissory notes,  the
Company  sold an aggregate principal  amount of approximately $412,000, $89,000,
$100,000, $100,000, $71,000 and $121,000 of such notes to affiliates of  Dillon,
Read  & Co.,  affiliates of  Gateway Associates,  ML Oklahoma  Venture Partners,
Limited Partnership, Advent  International Group, WestMed  Venture Partners  and
The  Woodlands Venture  Fund, L.P., respectively,  each of which  is a principal
stockholder of the Company. Don  E. Spyrison, a director  of the Company, is  an
affiliate  of The Woodlands Venture Fund, L.P. Joe D. Tippens, a director of the
Company, is a limited partner  of the general partner,  and a consultant to  the
management company, of ML Oklahoma Venture Partners, Limited Partnership.
 
    In  March  and April  1994, the  Company  sold at  $4.30 per  share 490,092,
 58,592,  24,092,  21,458, 61,086 and 75,283 shares of Series D Preferred  Stock
to  affiliates  of Dillon,  Read &  Co.,  The Woodlands  Venture Fund,  L.P., ML
Oklahoma  Venture   Partners,  Limited   Partnership,  affiliates   of   Gateway
Associates,   Advent   International   Group  and   WestMed   Venture  Partners,
respectively, each of which  is a principal stockholder  of the Company. Don  E.
Spyrison,  a director of the  Company, is an affiliate  of The Woodlands Venture
Fund, L.P. Joe D. Tippens,  a director of the Company,  is a limited partner  of
the  general partner, and a consultant to the management company, of ML Oklahoma
Venture Partners, Limited Partnership.
 
    In June 1995, the Company sold at $5.00 per share 270,130,  60,000,   45,000
and  200,000 shares of  Series E or  EG Preferred Stock  and related warrants to
purchase at $5.00 per share  an aggregate of 164,664  shares of Common Stock  to
affiliates  of Dillon, Read  & Co., an affiliate  of Gateway Associates, WestMed
Venture Partners and Kummell Investments Limited, respectively, each of which is
a principal stockholder of the Company.
 
                                       41
<PAGE>
          SECURITY OWNERSHIP OF MANAGEMENT AND PRINCIPAL STOCKHOLDERS
 
    The following table sets  forth information as of  May 1, 1996 (adjusted  to
give  effect to the automatic conversion  of all outstanding shares of Preferred
Stock, Class A Stock and  Class B Stock into  Common Stock immediately prior  to
the  closing of the Offering), and as adjusted to reflect the sale of the Common
Stock  offered  pursuant  to   the  Offering  (assuming   no  exercise  of   the
Underwriters'  over-allotment option), with respect  to the beneficial ownership
of Common Stock by each person known  by the Company to be the beneficial  owner
of  more than 5% of the outstanding shares of Common Stock, by each director and
executive officer of the Company and by all directors and executive officers  of
the Company as a group.
 
<TABLE>
<CAPTION>
                                                                                       BENEFICIAL OWNERSHIP (1)
                                                                                 -------------------------------------
                                                                                               PRIOR TO       AFTER
                               BENEFICIAL OWNER                                   SHARES(2)    OFFERING     OFFERING
- -------------------------------------------------------------------------------  -----------  -----------  -----------
<S>                                                                              <C>          <C>          <C>
Concord Partners II, L.P. affiliates (3).......................................    2,387,208        35.8%        25.2%
The Woodlands Venture Fund, L.P. (4)...........................................      536,148         8.1          5.7
  Martin P. Sutter (4).........................................................      536,148         8.1          5.7
Kummell Investments Limited (5)................................................      530,698         8.0          5.6
ML Oklahoma Venture Partners, Limited Partnership (6)..........................      509,174         7.7          5.4
Advent International Group (7).................................................      438,931         6.7          4.7
Gateway Associates affiliates (8)..............................................      437,335         6.6          4.6
WestMed Venture Partners (9)...................................................      410,977         6.2          4.4
Paul A. Brown, M.D.............................................................      --           --           --
Herbert J. Conrad (10).........................................................        6,250       *            *
Michael E. Herbert (11)........................................................        3,125       *            *
Louis M. Sherwood, M.D. (12)...................................................        6,250       *            *
Don E. Spyrison (4)............................................................      548,648         8.3          5.8
Joe D. Tippens (6).............................................................      509,174         7.7          5.4
William A. Hagstrom (13).......................................................      277,279         4.2          2.9
Socrates H. Choumbakos (14)....................................................      109,080         1.6          1.2
Mark G. Dimitroff (15).........................................................      101,734         1.6          1.1
Robert W. Veltri, Ph.D. (16)...................................................      100,414         1.5          1.1
All executive officers and directors as a group
 (12 persons) (17).............................................................    1,682,704        24.6         17.5
</TABLE>
 
- --------------------------
*   Less than 1%.
 
(1) Unless  otherwise noted, the Company believes  that each person named in the
    table has  sole voting  and  investment power  with  respect to  all  shares
    beneficially owned by such person.
 
(2) Each  beneficial owner's percentage ownership is determined by assuming that
    options, warrants and  other convertible  securities that are  held by  such
    person  (but not  those held  by any  other person)  and are  exercisable or
    convertible within 60  days have been  exercised or converted.  A person  is
    deemed to be the beneficial owner of securities that can be acquired by such
    person within 60 days upon the exercise of options or warrants or conversion
    of  convertible securities.  Percentage of  ownership is  based on 6,565,248
    shares of Common Stock outstanding before the Offering and 9,365,248  shares
    of Common Stock outstanding after the Offering.
 
(3) Includes  1,680,528 shares held by Concord  Partners II, L.P., which include
    86,527 shares issuable upon the exercise of certain stock purchase warrants,
    and 369,700 shares held  by Concord Partners  Japan, Limited, which  include
    5,170  shares issuable upon the exercise of certain stock purchase warrants,
    each of which is a  private venture capital fund  managed by Dillon, Read  &
    Co.  Inc. ("Dillon  Read"). Also  includes 28,290  shares held  by Lexington
    Partners III, L.P., and 13,143 shares  held by Lexington Partners IV,  L.P.,
    which  include  800  shares  issuable upon  the  exercise  of  certain stock
    purchase warrants, each of which is  a private investment fund, for  certain
    Dillon  Read affiliated persons, managed by  Dillon Read, and 295,547 shares
    held by Dillon Read as agent for certain affiliated persons of which  13,226
    shares  are issuable upon  the exercise of  certain stock purchase warrants.
    The address of such beneficial owners  is 535 Madison Avenue, New York,  New
    York 10022.
 
                                       42
<PAGE>
(4) The Woodlands Venture Partners, L.P. is the general partner of The Woodlands
    Venture  Fund, L.P.  Martin P.  Sutter and Don  E. Spyrison  are the general
    partners  of  The  Woodlands  Venture   Partners,  L.P.  Because  of   these
    relationships,  The Woodlands Venture  Partners, L.P., Martin  P. Sutter and
    Don E. Spyrison may  be deemed to  be the beneficial  owners of the  536,148
    shares held by The Woodlands Venture Fund, L.P. set forth in the table. Such
    shares  include an aggregate of 39,244  shares of Common Stock issuable upon
    exercise of certain  stock purchase  warrants. Messrs.  Sutter and  Spyrison
    disclaim such beneficial ownership. The address of such beneficial owners is
    2170 Buckthorne Place, Suite 170, The Woodlands, Texas 77380.
 
(5) The  beneficial owner's shares set forth  in the table include 40,000 shares
    of Common Stock issuable upon  exercise of certain stock purchase  warrants.
    The  address of  such beneficial owner  is Suite 922  C, Europort, Gibraltar
    (via London).
 
(6) The beneficial owner's shares set forth  in the table include 12,539  shares
    of  Common  Stock  issuable  upon the  exercise  of  certain  stock purchase
    warrants. The address of such beneficial owner is Meridian Tower, 5100  East
    Skelly  Drive, Suite 1060,  Tulsa, Oklahoma 74135. Mr.  Tippens is a limited
    partner of  the general  partner of  ML Oklahoma  Venture Partners,  Limited
    Partnership  ("ML Oklahoma"), and a consultant  to MLVC Inc., the management
    company to ML Oklahoma, and may be deemed to be the beneficial owner of  the
    509,174  shares held  by ML  Oklahoma set  forth in  the table.  Mr. Tippens
    disclaims beneficial ownership of such shares.
 
(7) The affiliates of Advent International Group  whose shares are set forth  in
    the   table  include   Rovent  Limited   Partnership,  Advent  International
    Technology Fund Limited Partnership, Advent International Investors  Limited
    Partnership,  Advent Omnibus Limited Partnership and Advent S.B.P.E. Limited
    Partnership. Such shares  include an  aggregate of 34,688  shares of  Common
    Stock  issuable upon  the exercise of  certain stock  purchase warrants. The
    address of such beneficial owners is 101 Federal Street, 5th Floor,  Boston,
    Massachusetts 02110.
 
(8) The affiliates of Gateway Associates whose shares are set forth in the table
    include  Gateway Venture  Partners II, L.P.  and Gateway  Partners L.P. Such
    shares include an aggregate of 47,168  shares of Common Stock issuable  upon
    the  exercise  of  certain  stock purchase  warrants.  The  address  of such
    beneficial owners is 8000 Maryland  Avenue, Suite 1190, St. Louis,  Missouri
    63105.
 
(9) The beneficial owner's shares set forth in the table include an aggregate of
    25,995  shares of Common  Stock issuable upon the  exercise of certain stock
    purchase warrants.  The address  of  such beneficial  owner is  200  Liberty
    Street, 39th Floor, New York, New York 10281.
 
(10)  The beneficial owner's shares set forth  in the table include 6,250 shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(11) The beneficial owner's shares set  forth in the table include 3,125  shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(12)  The beneficial owner's shares set forth  in the table include 6,250 shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(13) The beneficial owner's shares set forth in the table include 63,987  shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(14)  The beneficial owner's shares set forth in the table include 75,080 shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(15) The beneficial owner's shares set forth in the table include 19,690  shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(16)  The beneficial owner's shares set forth in the table include 26,580 shares
    of Common Stock issuable upon the exercise of certain stock options.
 
(17) See notes  (4), (6) and  (10) through  (16) to this  table. The  beneficial
    owners'  shares  set forth  in this  table include  an aggregate  of 273,495
    shares of Common Stock issuable upon  the exercise of certain stock  options
    and warrants.
 
                                       43
<PAGE>
                          DESCRIPTION OF CAPITAL STOCK
 
    The  following summary of certain provisions  of the capital stock of UroCor
does not purport to be complete and is subject to, and qualified in its entirety
by, the Restated Certificate of Incorporation and the By-laws which are included
as exhibits to the registration statement of which this Prospectus forms a  part
and by the provisions of applicable law.
 
AUTHORIZED AND OUTSTANDING CAPITAL STOCK
 
    The Company has an authorized capitalization of 26,579,759 shares of capital
stock  consisting of  6,000,000 shares  of Preferred  Stock, par  value $.01 per
share ("Preferred Stock"), 20,000,000 shares of Common Stock, 513,093 shares  of
Class  A Stock, par value $.01 per share ("Class A Stock"), and 66,666 shares of
Class B Stock, par  value $.01 per share  ("Class B Stock"). As  of the date  of
this   Prospectus  (and  giving  effect  to  the  automatic  conversion  of  all
outstanding shares of  Preferred Stock,  Class A Stock  and Class  B Stock  into
shares  of  Common Stock  immediately  prior to  the  closing of  the Offering),
6,565,248 shares of  Common Stock  were issued and  outstanding and  held by  50
stockholders of record, and no shares of Preferred Stock, Class A Stock or Class
B  Stock were outstanding. A total of  1,400,000 shares of Common Stock has been
reserved for grants of options under the 1992 Stock Option Plan. As of the  date
hereof,  an  aggregate of  1,487,904 shares  of Common  Stock were  reserved for
issuance upon exercise of options granted  under the 1992 Stock Option Plan  and
for issuance upon exercise of outstanding warrants.
 
    The  holders of the Common  Stock are entitled to one  vote per share in the
election of directors and in all  matters on which stockholders are entitled  or
permitted  to vote. Such holders  are not entitled to  vote cumulatively for the
election of directors. Holders of  Common Stock have no redemption,  conversion,
preemptive  or  other  subscription rights.  In  the event  of  the liquidation,
dissolution or winding up of the  Company, holders of Common Stock are  entitled
to  share ratably in all  of the assets of the  Company remaining, if any, after
satisfaction of the debts  and liabilities of the  Company and the  preferential
rights  of the  holders of  the Preferred Stock,  if any,  then outstanding. The
outstanding shares of Common Stock are,  and the shares of Common Stock  offered
pursuant  to the Offering will be, upon payment therefor as contemplated herein,
validly issued, fully paid and nonassessable.
 
    At present, there  is no  active trading market  for the  Common Stock.  The
Common  Stock has been approved for listing  on the Nasdaq National Market under
the symbol  "UCOR".  See  "Risk  Factors --  Absence  of  Prior  Public  Market;
Determination of Offering Price; Possible Volatility of Stock Price".
 
    Certain  of  the Company's  existing stockholders  have certain  rights with
respect to  the  registration  under  the Securities  Act  of  an  aggregate  of
5,886,601  shares of Common  Stock (the "Registrable  Shares"). In general, such
stockholders may demand  on up to  two occasions that  the Company register  the
sale of their shares of Common Stock. Each holder of Registrable Shares also has
piggy-back registration rights, subject to certain limitations, in the event the
Company proposes to register the sale of any shares of Common Stock or any other
securities  of  the  Company for  its  own account  or  for the  account  of its
stockholders. The Company is obligated to bear all of the expenses in connection
with the registration of the Registrable Shares, except underwriting commissions
and discounts. Any sales  of Registrable Shares will  be subject to the  180-day
lock-up described under "Shares Eligible for Future Sale" and "Underwriting".
 
CERTAIN ANTI-TAKEOVER EFFECTS OF CERTAIN PROVISIONS OF THE RESTATED CERTIFICATE
OF INCORPORATION, BY-LAWS AND DELAWARE GENERAL CORPORATION LAW
 
    The  Restated  Certificate  of  Incorporation  and  By-laws  contain certain
provisions that could  make more  difficult the  acquisition of  the Company  by
means  of  a  tender  or  exchange offer,  a  proxy  contest  or  otherwise. The
description of such provisions set forth below is intended only as a summary and
is qualified  in  its entirety  by  reference  to the  Restated  Certificate  of
Incorporation  and the  By-laws, each  of which  is filed  as an  exhibit to the
Registration Statement of which this Prospectus forms a part. See "Risk  Factors
- -- Control by Existing Stockholders; Possible Anti-Takeover Effects".
 
                                       44
<PAGE>
    CLASSIFIED  BOARD OF DIRECTORS.   The classification  of directors will have
the effect of making it difficult for stockholders to change the composition  of
the  Board of Directors. At least  two annual meetings of stockholders generally
will be required to effect a change  in the majority of the Board of  Directors.
Such  a delay may help  ensure that the Company's  directors, if confronted by a
stockholder attempting to force a proxy  contest, a tender or exchange offer  or
an extraordinary corporate transaction, would have sufficient time to review the
proposal  as well as  any available alternatives  to the proposal  and to act in
what  they  believe  to  be  the   best  interests  of  the  stockholders.   The
classification  provisions will apply  to every election  of directors, however,
regardless of whether  a change  in the composition  of the  Board of  Directors
would  be beneficial to the Company and  its stockholders and whether a majority
of the Company's stockholders believes that such a change would be desirable.
 
    The classification provisions also could  have the effect of discouraging  a
third  party from initiating a proxy contest,  making a tender or exchange offer
or otherwise attempting to  obtain control of the  Company, even though such  an
attempt  might  be  beneficial  to  the  Company  and  its  stockholders.  These
provisions could  thus increase  the likelihood  that incumbent  directors  will
retain   their  positions.  In  addition,   the  classification  provisions  may
discourage accumulations of large blocks of the Common Stock by purchasers whose
objective is to take control of the  Company and remove a majority of the  Board
of  Directors, and thus could  tend to reduce the  likelihood of fluctuations in
the market price  of the Common  Stock that might  result from accumulations  of
large  blocks for such  purpose. Accordingly, stockholders  could be deprived of
certain opportunities to sell  their shares of Common  Stock at a higher  market
price than might otherwise be the case.
 
    PREFERRED  STOCK.  The Restated  Certificate of Incorporation authorizes the
Board of Directors to  establish one or  more series of  Preferred Stock and  to
determine,  with respect to any series of  Preferred Stock, the terms and rights
of such series. The Company believes that the ability of the Board of  Directors
to  issue one or  more series of  Preferred Stock will  provide the Company with
flexibility in structuring  possible future  financing and  acquisitions and  in
meeting other corporate needs that may arise. The authorized shares of Preferred
Stock, as well as shares of Common Stock, will be available for issuance without
further  action by the Company's stockholders, unless such action is required by
applicable laws or the rules of any stock exchange or automated quotation system
on which the Company's securities may be listed or traded.
 
    Although the Board  of Directors  has no intention  at the  present time  of
doing  so, it could issue  a series of Preferred  Stock that could, depending on
the terms of such  series, impede the  completion of a  merger, tender offer  or
other  takeover attempt. The  Board of Directors will  make any determination to
issue such shares based on its judgment as to the best interests of the  Company
and  its  stockholders.  The  Board  of Directors,  in  so  acting,  could issue
Preferred Stock  having  terms  that could  discourage  an  acquisition  attempt
through which an acquiror may be otherwise able to change the composition of the
Board  of Directors, including  a tender or exchange  offer or other transaction
that some, or a majority, of the  Company's stockholders might believe to be  in
their  best interests or in which stockholders might receive a premium for their
stock over the then current market price of such stock.
 
    SPECIAL MEETING OF STOCKHOLDERS.  The By-laws provide that special  meetings
of  stockholders may be called only by  the President or the Board of Directors.
Such provisions,  together with  the  other anti-takeover  provisions  described
herein, also could have the effect of discouraging a third party from initiating
a  proxy contest, making a  tender or exchange offer  or otherwise attempting to
obtain control of the Company.
 
    NOTICE PROCEDURES.    The  By-laws  provide  that  stockholder  election  of
directors may be conducted only at annual meetings of stockholders and establish
advance  notice procedures with regard to  stockholder proposals relating to the
nomination of candidates for election as director. These procedures provide that
notice of such  stockholder proposals  must be timely  given in  writing to  the
Secretary  of the Company prior to the  annual meeting. Generally, to be timely,
notice must be received  at the principal executive  offices of the Company  not
less  than 60 days nor more than 90  days prior to an annual meeting. The notice
must contain certain information specified in the By-laws.
 
                                       45
<PAGE>
    DELAWARE ANTI-TAKEOVER  LAW.   Under  Section 203  of the  Delaware  General
Corporation   Law   (the  "Delaware   anti-takeover  law"),   certain  "business
combinations" between a Delaware corporation  whose stock generally is  publicly
traded  or held  of record  by more than  2,000 stockholders  and an "interested
stockholder" are prohibited for a three-year period following the date that such
stockholder became an  interested stockholder,  unless (i)  the corporation  has
elected  in its certificate of incorporation or bylaws not to be governed by the
Delaware anti-takeover law  (the Company has  not made such  an election),  (ii)
either  the  business  combination  or  the  transaction  that  resulted  in the
stockholder becoming  an interested  stockholder was  approved by  the board  of
directors  of the corporation before the other party to the business combination
became an interested  stockholder, (iii)  upon consummation  of the  transaction
that  made it  an interested  stockholder, the  interested stockholder  owned at
least 85% of the voting stock of the corporation outstanding at the commencement
of the  transaction (excluding  voting stock  owned by  directors who  are  also
officers  or held in employee  stock plans in which the  employees do not have a
right to determine confidentially  whether to tender or  vote stock held by  the
plan),  or  (iv)  on  or  subsequent  to  the  date  the  stockholder  became an
"interested stockholder", the business combination was approved by the board  of
directors  of the corporation and ratified by  66 2/3% of the voting stock which
the interested  stockholder did  not own.  The three-year  prohibition does  not
apply  to certain  business combinations  proposed by  an interested stockholder
following the announcement or notification of certain extraordinary transactions
involving  the  corporation  and  a  person  who  had  not  been  an  interested
stockholder  during  the  previous  three  years  or  who  became  an interested
stockholder with the approval of a majority of the corporation's directors.  The
term   "business  combination"  is  defined  generally  to  include  mergers  or
consolidations between  a Delaware  corporation and  an interested  stockholder,
transactions with an interested stockholder involving the assets or stock of the
corporation  or its majority-owned subsidiaries  and transactions which increase
an interested stockholder's percentage ownership of stock. The term  "interested
stockholder"  is defined generally  as a stockholder  who becomes the beneficial
owner of 15% or more of a Delaware corporation's voting stock. Section 203 could
have the effect of delaying, deferring or preventing a change in control of  the
Company.
 
LIMITATION ON DIRECTORS' LIABILITY AND INDEMNIFICATION OF DIRECTORS AND OFFICERS
 
    The  Restated Certificate of  Incorporation provides that  a director of the
Company shall not be  personally liable to the  Company or its stockholders  for
monetary  damages  for  breach  of  fiduciary duty  as  a  director,  except for
liability (i) for any breach of the director's duty of loyalty to the Company or
its stockholders, (ii) for acts or omissions not in good faith or which  involve
intentional misconduct or a knowing violation of law, (iii) under Section 174 of
the  Delaware General Corporation Law or (iv) for any transaction from which the
director derived  an  improper personal  benefit.  The Company  is  required  to
indemnify  any director who,  as the result of  his acting as  a director of the
Company, was  or  is a  party  or  is threatened  to  be  made a  party  to  any
threatened,  pending or contemplated action,  suit or proceeding, whether civil,
criminal, administrative  or  investigative, to  the  full extent  permitted  by
Delaware law.
 
    Insofar  as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers  and controlling persons of the  Company
pursuant to the foregoing provisions, or otherwise, the Company has been advised
that   in  the   opinion  of  the   Securities  and   Exchange  Commission  such
indemnification is against public policy as expressed in the Securities Act  and
is, therefore, unenforceable.
 
TRANSFER AGENT AND REGISTRAR
 
    The  transfer agent  and registrar  for the  Common Stock  is American Stock
Transfer & Trust Company, New York, New York.
 
                                       46
<PAGE>
                        SHARES ELIGIBLE FOR FUTURE SALE
 
    Prior to the Offering, there has been no public market for the Common Stock,
and no prediction can be made as to the effect, if any, that the sale of  shares
or  the availability  of shares for  sale will have  on the market  price of the
Common Stock prevailing from  time to time.  Nevertheless, sales of  substantial
amounts  of Common Stock in the  public market could adversely affect prevailing
market prices and  the ability of  the Company  to raise equity  capital in  the
future. See "Underwriting".
 
    Upon  consummation  of  the  Offering,  the  Company  will  have outstanding
9,365,248 shares  of Common  Stock (assuming  no exercise  of the  Underwriters'
over-allotment  option).  The  2,800,000 shares  of  Common Stock  sold  in this
Offering will be freely tradeable  within the public market without  restriction
or  further  registration  under  the  Securities  Act,  except  for  any shares
purchased by "affiliates" of the  Company, as that term  is defined in Rule  144
("Rule  144")  promulgated under  the  Securities Act.  The  remaining 6,565,248
outstanding shares  of Common  Stock are  deemed to  be "restricted  securities"
within  the meaning of  Rule 144 and  may be publicly  resold only if registered
under the Securities Act or sold  in accordance with an eligible exemption  from
registration, such as Rule 144.
 
    The  Company, its executive officers  and directors and certain stockholders
of the Company have agreed that, for a period of 180 days after the date of this
Prospectus, they  will not,  directly or  indirectly, offer,  sell, contract  to
sell,  grant any option to sell or otherwise dispose of, directly or indirectly,
any shares of Common Stock or  securities convertible into or exchangeable  for,
or  any rights to purchase  or acquire, Common Stock,  without the prior written
consent of Montgomery Securities. Montgomery Securities, in its sole  discretion
and at any time without notice, may release all or any portion of the securities
subject to the 180-day lock-up agreement.
 
    Of the 6,565,248 shares of Common Stock held by existing stockholders of the
Company,  (i)  approximately 214,000  will be  eligible for  sale in  the public
market immediately following the Offering  and (ii) an additional  approximately
5,506,000  shares will be  eligible for resale in  the public market immediately
following the  expiration  of the  180-day  lock-up described  above,  of  which
approximately   1,539,000  shares  are  subject  to  certain  volume  and  other
restrictions under Rule 144.
 
    The 6,565,248  shares of  Common Stock  originally issued  and sold  by  the
Company  in private transactions  in reliance upon  exemptions from registration
under the  Securities Act  and held  by stockholders  upon consummation  of  the
Offering are "restricted securities" as that term is defined in Rule 144 and may
be  sold in the public market only  if registered or if exempt from registration
under the Securities Act.
 
    In general, under  Rule 144  as currently in  effect, a  person (or  persons
whose  shares  are required  to be  aggregated), including  an affiliate  of the
Company, who beneficially owns "restricted securities" acquired from the Company
or an affiliate of the Company at least two years prior to the sale is  entitled
to  sell within any three-month period the number of shares that does not exceed
the  greater  of  (i)  1%  of  the  then  outstanding  shares  of  Common  Stock
(approximately   93,652  shares  based  on  the  number  of  shares  outstanding
immediately upon  completion  of  the  Offering, assuming  no  exercise  of  the
Underwriters'  over-allotment  option)  and  (ii)  the  average  weekly reported
trading volume of the  Common Stock during the  four calendar weeks  immediately
preceding the date on which notice of such sale is filed with the Securities and
Exchange Commission (the "Commission"), provided that certain manner of sale and
notice  requirements  and  requirements  as to  availability  of  current public
information concerning the Company are  satisfied (which requirements as to  the
availability  of  current  public  information  are  expected  to  be  satisfied
commencing 90 days  after the  date of this  Prospectus). Under  Rule 144(k),  a
person  who has  not been  an affiliate for  the Company  for a  period of three
months preceding a  sale of securities  by him, and  who beneficially owns  such
"restricted securities" acquired from the Company or an affiliate of the Company
at  least three years prior to such sale,  would be entitled to sell such shares
without regard to  volume limitations, manner  of sale provisions,  notification
requirements   or  requirements  as  to   the  availability  of  current  public
information concerning the Company. Shares held by persons who are deemed to  be
affiliates  of the Company,  including any shares acquired  by affiliates in the
Offering, are subject  to such  volume limitations, manner  of sale  provisions,
 
                                       47
<PAGE>
notification  requirements and requirements as to availability of current public
information concerning the Company, regardless of how long the shares have  been
owned  or how they were  acquired and, in addition,  the sale of any "restricted
securities" beneficially owned by affiliates is subject to the two-year  holding
period  requirement. As defined  in Rule 144,  an "affiliate" of  an issuer is a
person that directly or indirectly through the use of one or more intermediaries
controls, or is controlled by or is under common control with, such issuer.
 
    Any employee,  officer or  director of,  or consultant  to the  Company  who
purchased  his or her shares pursuant to a written compensatory plan or contract
is entitled  to  rely  on  the  resale provisions  of  Rule  701,  which  permit
non-affiliates  to sell their Rule 701  shares without complying with the public
information, holding period, volume limitation or notice provisions of Rule 144,
and which permit affiliates to sell their Rule 701 shares without complying with
the Rule 144 holding period restrictions, in each case commencing 90 days  after
the date of this Prospectus.
 
    The  Company intends to file a registration  statement on Form S-8 under the
Securities Act to register  shares of Common Stock  reserved for issuance  under
the  1992  Stock Option  Plan,  thus permitting  the  resale of  such  shares by
non-affiliates in the  public market without  restrictions under the  Securities
Act.  Such registration statement is expected  to become effective shortly after
the expiration of the 180-day  lock-up described above. As  of the date of  this
Prospectus,   options  to  purchase  1,001,594   shares  of  Common  Stock  were
outstanding, of which options  to purchase 358,180 shares  of Common Stock  were
vested. Of those vested, 239,430 shares are subject to the 180-day lock-up, and,
therefore,  118,750 shares of Common Stock will  be available for sale after the
effective date of the  registration statement on Form  S-8 upon the exercise  of
options.
 
    As  of the  date of  this Prospectus, warrants  to purchase  an aggregate of
486,310 shares of  Common Stock were  outstanding, of which  344,734 shares  are
subject to the 180-day lock-up.
 
    See  "Description of Capital Stock" for information regarding certain rights
to require the Company to register shares of Common Stock.
 
                                       48
<PAGE>
                                  UNDERWRITING
 
    The Underwriters  named  below,  represented by  Montgomery  Securities  and
Volpe,  Welty & Company (the  "Representatives"), have severally agreed, subject
to the terms and conditions set forth in the Underwriting Agreement, to purchase
from the Company the number of  shares of Common Stock indicated below  opposite
their   respective  names  at  the  initial   public  offering  price  less  the
underwriting discount  set forth  on  the cover  page  of this  Prospectus.  The
Underwriting  Agreement provides  that the  obligations of  the Underwriters are
subject to certain conditions precedent, and that the Underwriters are committed
to purchase all of the shares if they purchase any.
 
<TABLE>
<CAPTION>
                                                                                    NUMBER OF
UNDERWRITER                                                                          SHARES
- ---------------------------------------------------------------------------------  -----------
<S>                                                                                <C>
Montgomery Securities............................................................
Volpe, Welty & Company...........................................................
 
                                                                                   -----------
    Total........................................................................    2,800,000
                                                                                   -----------
                                                                                   -----------
</TABLE>
 
    The Representatives have advised the  Company that the Underwriters  propose
initially  to offer the Common Stock to the public on the terms set forth on the
cover page of this Prospectus. The Underwriters may allow to selected dealers  a
concession  of not more than $    per share; and the Underwriters may allow, and
such dealers may  reallow, a  concession of  not more than  $      per share  to
certain  other dealers. After the Offering, the offering price and other selling
terms may be changed by the Representatives. The Common Stock is offered subject
to receipt and acceptance by the Underwriters, and to certain other  conditions,
including the right to reject orders in whole or in part.
 
    The  Company has granted  an option to  the Underwriters, exercisable during
the 30-day period after the date of this Prospectus, to purchase up to a maximum
of 420,000 additional shares of Common  Stock to cover over-allotments, if  any,
at  the  same price  per share  as the  initial  shares to  be purchased  by the
Underwriters. To  the extent  that the  Underwriters exercise  this option,  the
Underwriters  will be committed, subject to certain conditions, to purchase such
additional shares in approximately the same proportion as set forth in the above
table. The Underwriters may purchase  such shares only to cover  over-allotments
made in connection with the Offering.
 
    The  Underwriting  Agreement provides  that the  Company will  indemnify the
Underwriters against certain liabilities, including civil liabilities under  the
Securities  Act, or will contribute to payments the Underwriters may be required
to make in respect thereof.
 
    The  Company,  its  directors  and  executive  officers  and  certain  other
stockholders  of the Company have agreed that for a period of 180 days after the
date of this  Prospectus, they will  not, directly or  indirectly, offer,  sell,
contract  to sell, grant any option to sell or otherwise dispose of, directly or
indirectly, any  shares  of  Common  Stock or  securities  convertible  into  or
exchangeable for, or any rights to purchase or acquire, Common Stock without the
prior  written consent of  Montgomery Securities. Montgomery  Securities may, in
its sole discretion and  at any time  without prior notice,  release all or  any
portion of the shares of Common Stock subject to the lock-up agreements.
 
    In  August  1995,  UroCor  paid Montgomery  Securities  $75,000  for certain
financial advisory services.
 
    The Representatives have informed the  Company that the Underwriters do  not
expect to make sales of Common Stock offered by this Prospectus to accounts over
which they exercise discretionary authority in excess of 5% of the Offering.
 
                                       49
<PAGE>
    Prior to the Offering, there has been no public market for the Common Stock.
Consequently,   the  initial  public  offering   price  will  be  determined  by
negotiations between the Company and  the Representatives. Among the factors  to
be  considered in such  negotiations will be  the history of,  and the prospects
for, the Company and  the industry in  which it competes,  an assessment of  the
Company's  management, the Company's  past and present  operations, its past and
present earnings  and the  trend  of such  earnings,  the prospects  for  future
earnings  of the  Company, the present  state of the  Company's development, the
general condition of the securities markets at the time of the Offering and  the
market  price  of and  demand for  publicly-traded  common stocks  of comparable
companies in recent periods. The  estimated initial public offering price  range
set  forth on the cover page of this Prospectus is subject to change as a result
of market conditions and other factors.
 
    The Common Stock has been approved for listing on the Nasdaq National Market
under the symbol "UCOR".
 
                                 LEGAL MATTERS
 
    The legality of  the Common  Stock offered hereby  will be  passed upon  for
UroCor by Fulbright & Jaworski L.L.P., Houston, Texas. Certain legal matters for
the Underwriters will be passed upon by Cooley Godward Castro Huddleson & Tatum,
Menlo Park, California.
 
                                    EXPERTS
 
    The  financial  statements  and schedule  of  the Company  included  in this
Prospectus and  elsewhere in  the Registration  Statement have  been audited  by
Arthur  Andersen  LLP, independent  public  accountants, as  indicated  in their
reports with  respect thereto  and  are included  herein  in reliance  upon  the
authority  of said  firm as  experts in accounting  and auditing  in giving said
reports.
 
                             AVAILABLE INFORMATION
 
    UroCor has filed with  the Commission a Registration  Statement on Form  S-1
(the  "Registration Statement")  under the  Securities Act  with respect  to the
Common Stock offered by  this Prospectus. This  Prospectus, which constitutes  a
part  of the  Registration Statement,  does not  contain all  of the information
contained in  the  Registration Statement  and  in the  exhibits  and  schedules
thereto,  certain portions of  which are omitted  as permitted by  the rules and
regulations of  the Commission.  For  further information  with respect  to  the
Company  and the Common Stock  offered by this Prospectus,  reference is made to
the Registration Statement, including the exhibits thereto. Statements contained
in this Prospectus as to the contents of any contract or other document filed as
an exhibit to the  Registration Statement are not  necessarily complete, and  in
each  instance reference is  hereby made to  the copy of  such contract or other
documents filed  as an  exhibit to  the Registration  Statement, each  statement
being qualified in all respects by such reference.
 
    The  Registration Statement  and the exhibits  and schedules  thereto may be
inspected, without charge, and copies may be obtained at prescribed rates at the
Public Reference Section of  the Commission at Room  1024, Judiciary Plaza,  450
Fifth  Street, N.W., Washington, D.C. 20549, and  at the regional offices of the
Commission at Northwestern Atrium Center,  500 West Madison Street, 14th  Floor,
Chicago,  Illinois 60661 and Seven World Trade Center, 13th Floor, New York, New
York 10048.
 
    Prior to  the  Offering,  UroCor  has not  been  subject  to  the  reporting
requirements  of the  Securities Exchange Act  of 1934, as  amended. The Company
intends to  furnish  its stockholders  with  annual reports  containing  audited
financial statements reported on by independent public accountants following the
end  of each  fiscal year  and such interim  reports as  it may  determine to be
necessary or desirable.
 
                                       50
<PAGE>
                              FINANCIAL STATEMENTS
                         INDEX TO FINANCIAL STATEMENTS
 
<TABLE>
<CAPTION>
                                                                                                                PAGE
                                                                                                                -----
 
<S>                                                                                                          <C>
Report of Independent Public Accountants...................................................................         F-2
 
Balance Sheets.............................................................................................         F-3
 
Statements of Operations...................................................................................         F-4
 
Statements of Stockholders' Equity.........................................................................         F-5
 
Statements of Cash Flows...................................................................................         F-6
 
Notes to Financial Statements..............................................................................         F-7
</TABLE>
 
                                      F-1
<PAGE>
                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS
 
To the Board of Directors of
UroCor, Inc.:
 
    We  have audited the accompanying balance sheets of UroCor, Inc. (a Delaware
corporation) as of  December 31, 1994  and 1995, and  the related statements  of
operations,  stockholders' equity and cash flows for  each of the three years in
the  period  ended  December  31,  1995.  These  financial  statements  are  the
responsibility  of the Company's management. Our responsibility is to express an
opinion on these financial statements based on our audits.
 
    We conducted  our  audits in  accordance  with generally  accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement. An audit includes examining, on a test basis, evidence  supporting
the  amounts and disclosures in the financial statements. An audit also includes
assessing the  accounting  principles used  and  significant estimates  made  by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
 
    In our opinion, the financial  statements referred to above present  fairly,
in  all material respects, the financial position of UroCor, Inc. as of December
31, 1994 and 1995, and the results of its operations and its cash flows for each
of the three  years in the  period ended  December 31, 1995  in conformity  with
generally accepted accounting principles.
 
Oklahoma City, Oklahoma                   ARTHUR ANDERSEN LLP
March 29, 1996
 
                                      F-2
<PAGE>
                                  UROCOR, INC.
                                 BALANCE SHEETS
                                     ASSETS
<TABLE>
<CAPTION>
                                                                                                          MARCH 31,
                                                                                                        --------------
                                                                                                             1995
                                                                                 DECEMBER 31,           --------------
                                                                        ------------------------------
                                                                             1994            1995        (UNAUDITED)
                                                                        --------------  --------------
<S>                                                                     <C>             <C>             <C>
CURRENT ASSETS:
  Cash and cash equivalents...........................................  $    1,822,924  $    3,125,296  $    1,459,589
  Accounts receivable, net of allowance for doubtful accounts of
   $670,845 and $982,046 at December 31, 1994 and 1995 and $756,163
   and $822,044 at March 31, 1995 and 1996............................       2,460,109       4,405,100       3,008,235
  Prepaid expenses....................................................         279,048         421,648         330,868
  Laboratory supplies, at average cost................................         323,333         234,145         254,491
  Other current assets................................................          39,961         119,862          63,314
                                                                        --------------  --------------  --------------
    Total current assets..............................................       4,925,375       8,306,051       5,116,497
                                                                        --------------  --------------  --------------
PROPERTY AND EQUIPMENT, net...........................................       1,967,039       2,443,737       1,892,351
INTANGIBLE AND OTHER ASSETS, net......................................       1,053,749       1,743,722       1,034,742
                                                                        --------------  --------------  --------------
    Total assets......................................................  $    7,946,163  $   12,493,510  $    8,043,590
                                                                        --------------  --------------  --------------
                                                                        --------------  --------------  --------------
                                 LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES:
  Accounts payable....................................................         386,482         487,731         296,314
  Accrued compensation................................................         684,814         873,590         568,474
  Other accrued liabilities...........................................         337,839         180,620         313,031
  Current installments of obligations under capital leases............         605,330         860,088         650,028
                                                                        --------------  --------------  --------------
    Total current liabilities.........................................       2,014,465       2,402,029       1,827,847
COMMITMENTS AND CONTINGENCIES (Note 7)................................        --              --              --
LINE OF CREDIT........................................................       1,000,000         700,000       1,250,000
OBLIGATIONS UNDER CAPITAL LEASES, net of current installments.........       1,063,004         966,485         996,833
                                                                        --------------  --------------  --------------
    Total liabilities.................................................       4,077,469       4,068,514       4,074,680
                                                                        --------------  --------------  --------------
STOCKHOLDERS' EQUITY:
  Convertible preferred stock, $.01 par value -- authorized 9,177,357
   shares at December 31, 1994 and March 31, 1995, 10,132,791 shares
   at December 31, 1995 and 6,000,000 shares at March 31, 1996 issued
   in series; 4,883,075 shares outstanding at December 31, 1994 and
   March 31, 1995 and 5,706,395 shares outstanding at December 31,
   1995 and March 31, 1996............................................          48,831          57,064          48,831
  Class A stock, $.01 par value -- authorized 590,674 shares in 1994
   and 1995 and 513,093 shares at March 31, 1996; 513,093 shares
   issued and outstanding.............................................           5,131           5,131           5,131
  Class B stock, $.01 par value -- authorized, issued and outstanding
   66,666 shares......................................................             667             667             667
  Common stock, $.01 par value, authorized 8,000,000 shares at
   December 31, 1994 and March 31, 1995, 8,700,000 shares at December
   31, 1995 and 20,000,000 shares at March 31, 1996; no shares issued
   and outstanding in 1994; 69,188 issued and outstanding at December
   31, 1995 and 22,687 and 81,688 issued and outstanding at March 31,
   1995 and 1996......................................................        --                   692             227
  Additional paid-in capital..........................................      18,701,314      22,716,005      18,709,028
  Accumulated deficit.................................................     (14,887,249)    (14,354,563)    (14,794,974)
                                                                        --------------  --------------  --------------
    Total stockholders' equity........................................       3,868,694       8,424,996       3,968,910
                                                                        --------------  --------------  --------------
    Total liabilities and stockholders' equity........................  $    7,946,163  $   12,493,510  $    8,043,590
                                                                        --------------  --------------  --------------
                                                                        --------------  --------------  --------------
 
<CAPTION>
 
                                                                             1996
                                                                        --------------
 
<S>                                                                     <C>
CURRENT ASSETS:
  Cash and cash equivalents...........................................  $    1,300,846
  Accounts receivable, net of allowance for doubtful accounts of
   $670,845 and $982,046 at December 31, 1994 and 1995 and $756,163
   and $822,044 at March 31, 1995 and 1996............................       4,981,790
  Prepaid expenses....................................................         619,049
  Laboratory supplies, at average cost................................         422,248
  Other current assets................................................         144,804
                                                                        --------------
    Total current assets..............................................       7,468,737
                                                                        --------------
PROPERTY AND EQUIPMENT, net...........................................       2,727,091
INTANGIBLE AND OTHER ASSETS, net......................................       1,838,442
                                                                        --------------
    Total assets......................................................  $   12,034,270
                                                                        --------------
                                                                        --------------
                                 LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES:
  Accounts payable....................................................         425,439
  Accrued compensation................................................         747,667
  Other accrued liabilities...........................................         379,644
  Current installments of obligations under capital leases............         829,622
                                                                        --------------
    Total current liabilities.........................................       2,382,372
COMMITMENTS AND CONTINGENCIES (Note 7)................................        --
LINE OF CREDIT........................................................        --
OBLIGATIONS UNDER CAPITAL LEASES, net of current installments.........         950,238
                                                                        --------------
    Total liabilities.................................................       3,332,610
                                                                        --------------
STOCKHOLDERS' EQUITY:
  Convertible preferred stock, $.01 par value -- authorized 9,177,357
   shares at December 31, 1994 and March 31, 1995, 10,132,791 shares
   at December 31, 1995 and 6,000,000 shares at March 31, 1996 issued
   in series; 4,883,075 shares outstanding at December 31, 1994 and
   March 31, 1995 and 5,706,395 shares outstanding at December 31,
   1995 and March 31, 1996............................................          57,064
  Class A stock, $.01 par value -- authorized 590,674 shares in 1994
   and 1995 and 513,093 shares at March 31, 1996; 513,093 shares
   issued and outstanding.............................................           5,131
  Class B stock, $.01 par value -- authorized, issued and outstanding
   66,666 shares......................................................             667
  Common stock, $.01 par value, authorized 8,000,000 shares at
   December 31, 1994 and March 31, 1995, 8,700,000 shares at December
   31, 1995 and 20,000,000 shares at March 31, 1996; no shares issued
   and outstanding in 1994; 69,188 issued and outstanding at December
   31, 1995 and 22,687 and 81,688 issued and outstanding at March 31,
   1995 and 1996......................................................             817
  Additional paid-in capital..........................................      22,761,905
  Accumulated deficit.................................................     (14,123,924)
                                                                        --------------
    Total stockholders' equity........................................       8,701,660
                                                                        --------------
    Total liabilities and stockholders' equity........................  $   12,034,270
                                                                        --------------
                                                                        --------------
</TABLE>
 
      The accompanying notes are an integral part of these balance sheets.
 
                                      F-3
<PAGE>
                                  UROCOR, INC.
                            STATEMENTS OF OPERATIONS
<TABLE>
<CAPTION>
                                                                                                             THREE MONTHS
                                                                                                                ENDED
                                                                                                              MARCH 31,
                                                                                                             ------------
                                                                                                                 1995
                                                                        YEAR ENDED DECEMBER 31,              ------------
                                                             ----------------------------------------------
                                                                  1993            1994            1995       (UNAUDITED)
                                                             --------------  --------------  --------------
<S>                                                          <C>             <C>             <C>             <C>
REVENUE....................................................  $    9,348,498  $   14,531,008  $   19,758,170  $  4,618,955
                                                             --------------  --------------  --------------  ------------
OPERATING EXPENSES:
  Direct cost of services and products.....................       3,893,380       5,891,487       7,353,676     1,658,302
  Selling, general and administrative expenses.............       6,308,134       8,764,598       9,423,216     2,254,735
  Research and development.................................       1,252,009       1,969,076       2,267,102       558,264
                                                             --------------  --------------  --------------  ------------
    Total operating expenses...............................      11,453,523      16,625,161      19,043,994     4,471,301
                                                             --------------  --------------  --------------  ------------
  Income (loss) from operations............................      (2,105,025)     (2,094,153)        714,176       147,654
OTHER INCOME (EXPENSE):
  Interest income..........................................          45,161         103,992         108,983        15,637
  Interest expense.........................................        (108,549)       (307,239)       (290,473)      (71,018)
                                                             --------------  --------------  --------------  ------------
    Total other income (expense)...........................         (63,388)       (203,247)       (181,490)      (55,381)
                                                             --------------  --------------  --------------  ------------
Income (loss) before income taxes..........................      (2,168,413)     (2,297,400)        532,686        92,273
Income taxes (benefit).....................................        --              --              --             --
                                                             --------------  --------------  --------------  ------------
NET INCOME (LOSS)..........................................  $   (2,168,413) $   (2,297,400) $      532,686  $     92,273
                                                             --------------  --------------  --------------  ------------
                                                             --------------  --------------  --------------  ------------
NET INCOME (LOSS) PER SHARE................................  $         (.41) $         (.38) $          .07  $        .01
                                                             --------------  --------------  --------------  ------------
                                                             --------------  --------------  --------------  ------------
SHARES USED IN COMPUTING NET INCOME (LOSS) PER SHARE.......       5,232,636       6,104,035       7,295,548     6,587,933
                                                             --------------  --------------  --------------  ------------
                                                             --------------  --------------  --------------  ------------
 
<CAPTION>
 
                                                                 1996
                                                             ------------
 
<S>                                                          <C>
REVENUE....................................................  $  5,907,549
                                                             ------------
OPERATING EXPENSES:
  Direct cost of services and products.....................     2,138,043
  Selling, general and administrative expenses.............     2,861,877
  Research and development.................................       643,772
                                                             ------------
    Total operating expenses...............................     5,643,692
                                                             ------------
  Income (loss) from operations............................       263,857
OTHER INCOME (EXPENSE):
  Interest income..........................................        23,288
  Interest expense.........................................       (56,506)
                                                             ------------
    Total other income (expense)...........................       (33,218)
                                                             ------------
Income (loss) before income taxes..........................       230,639
Income taxes (benefit).....................................       --
                                                             ------------
NET INCOME (LOSS)..........................................  $    230,639
                                                             ------------
                                                             ------------
NET INCOME (LOSS) PER SHARE................................  $        .03
                                                             ------------
                                                             ------------
SHARES USED IN COMPUTING NET INCOME (LOSS) PER SHARE.......     7,522,946
                                                             ------------
                                                             ------------
</TABLE>
 
   The accompanying notes are an integral part of these financial statements.
 
                                      F-4
<PAGE>
                                  UROCOR, INC.
                       STATEMENTS OF STOCKHOLDERS' EQUITY
<TABLE>
<CAPTION>
                              CONVERTIBLE PREFERRED
                                      STOCK
                               -- ISSUED IN SERIES        CLASS A STOCK             CLASS B STOCK                COMMON STOCK
                              ----------------------  ----------------------  --------------------------  --------------------------
                               SHARES     PAR VALUE    SHARES     PAR VALUE     SHARES       PAR VALUE      SHARES       PAR VALUE
                              ---------  -----------  ---------  -----------  -----------  -------------  -----------  -------------
<S>                           <C>        <C>          <C>        <C>          <C>          <C>            <C>          <C>
BALANCE AT DECEMBER 31,
 1992.......................  3,728,678   $  37,287     513,093   $   5,131       66,666     $     667        --         $  --
Net loss....................     --          --          --          --           --            --            --            --
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
BALANCE AT DECEMBER 31,
 1993.......................  3,728,678   $  37,287     513,093   $   5,131       66,666     $     667        --         $  --
Stock issuance -- New Series
 D..........................  1,154,397      11,544      --          --           --            --            --            --
Net loss....................     --          --          --          --           --            --            --            --
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
BALANCE AT DECEMBER 31,
 1994.......................  4,883,075   $  48,831     513,093   $   5,131       66,666     $     667        --         $  --
Stock issuance -- New Series
 E/EG.......................    823,320       8,233      --          --           --            --            --            --
Exercise of stock options...     --          --          --          --           --            --            69,188           692
Net income..................     --          --          --          --           --            --            --            --
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
BALANCE AT DECEMBER 31,
 1995.......................  5,706,395   $  57,064     513,093   $   5,131       66,666     $     667        69,188     $     692
Exercise of stock options
 (unaudited)................     --          --          --          --           --            --            12,500           125
Stock option -- compensation
 expense (unaudited)........     --          --          --          --           --            --            --            --
Net income (unaudited)......     --          --          --          --           --            --            --            --
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
BALANCE AT MARCH 31, 1996
 (unaudited)................  5,706,395   $  57,064     513,093   $   5,131       66,666     $     667        81,688     $     817
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
                              ---------  -----------  ---------  -----------  -----------        -----    -----------        -----
 
<CAPTION>
 
                              ADDITIONAL                      TOTAL
                                PAID-IN     ACCUMULATED   STOCKHOLDERS'
                                CAPITAL       DEFICIT        EQUITY
                              -----------  -------------  -------------
<S>                           <C>          <C>            <C>
BALANCE AT DECEMBER 31,
 1992.......................  $13,913,988   $(10,421,436)  $ 3,535,637
Net loss....................      --         (2,168,413)    (2,168,413)
                              -----------  -------------  -------------
BALANCE AT DECEMBER 31,
 1993.......................  $13,913,988   $(12,589,849)  $ 1,367,224
Stock issuance -- New Series
 D..........................    4,787,326       --           4,798,870
Net loss....................      --         (2,297,400)    (2,297,400)
                              -----------  -------------  -------------
BALANCE AT DECEMBER 31,
 1994.......................  $18,701,314   $(14,887,249)  $ 3,868,694
Stock issuance -- New Series
 E/EG.......................    3,989,567       --           3,997,800
Exercise of stock options...       25,124       --              25,816
Net income..................      --            532,686        532,686
                              -----------  -------------  -------------
BALANCE AT DECEMBER 31,
 1995.......................  $22,716,005   $(14,354,563)  $ 8,424,996
Exercise of stock options
 (unaudited)................       12,375       --              12,500
Stock option -- compensation
 expense (unaudited)........       33,525       --              33,525
Net income (unaudited)......      --            230,639        230,639
                              -----------  -------------  -------------
BALANCE AT MARCH 31, 1996
 (unaudited)................  $22,761,905   $(14,123,924)  $ 8,701,660
                              -----------  -------------  -------------
                              -----------  -------------  -------------
</TABLE>
 
   The accompanying notes are an integral part of these financial statements.
 
                                      F-5
<PAGE>
                                  UROCOR, INC.
 
                            STATEMENTS OF CASH FLOWS
 
<TABLE>
<CAPTION>
                                                                                                             THREE MONTHS ENDED
                                                                      YEAR ENDED DECEMBER 31,                    MARCH 31,
                                                            -------------------------------------------  --------------------------
                                                                1993           1994           1995           1995          1996
                                                            -------------  -------------  -------------  ------------  ------------
                                                                                                                (UNAUDITED)
<S>                                                         <C>            <C>            <C>            <C>           <C>
CASH FLOWS FROM OPERATING ACTIVITIES:
  Net income (loss).......................................  $  (2,168,413) $  (2,297,400) $     532,686  $     92,273  $    230,639
  Adjustments to reconcile net income (loss) to net cash
   used in operating activities:
    Depreciation and amortization.........................        417,966        681,261        875,557       208,689       251,742
    Stock option compensation expense.....................       --             --             --             --             33,525
    Conversion of accrued interest on convertible
     promissory notes.....................................       --               37,333       --             --            --
    Other.................................................          4,892          5,789          4,480          (296)       (2,121)
    Changes in assets and liabilities:
      Increase in accounts receivable, net................       (634,251)      (744,191)    (1,944,991)     (548,126)     (576,690)
      Increase in prepaid expenses........................       (154,168)       (77,745)      (142,600)      (51,820)     (197,401)
      (Increase) decrease in laboratory supplies..........        (33,949)      (216,097)        89,188        68,842      (188,103)
      Increase in other current assets....................         (1,549)       (37,761)       (79,901)      (23,353)      (24,942)
      Increase (decrease) in accounts payable.............        106,593         46,031        101,249       (90,168)      (62,292)
      Increase (decrease) in accrued compensation.........        225,535         14,735        188,776      (116,340)     (125,923)
      Increase (decrease) in other accrued liabilities....        (62,586)       151,548       (157,219)      (24,808)      199,024
                                                            -------------  -------------  -------------  ------------  ------------
      Net cash used in operating activities...............     (2,299,930)    (2,436,497)      (532,775)     (485,107)     (462,542)
                                                            -------------  -------------  -------------  ------------  ------------
CASH FLOWS FROM INVESTING ACTIVITIES:
  Capital expenditures....................................     (1,621,944)      (987,261)    (1,362,599)     (125,764)     (535,509)
  Intangible and other assets.............................        (78,382)      (923,181)      (692,973)       19,007       (94,720)
                                                            -------------  -------------  -------------  ------------  ------------
      Net cash used in investing activities...............     (1,700,326)    (1,910,442)    (2,055,572)     (106,757)     (630,229)
                                                            -------------  -------------  -------------  ------------  ------------
CASH FLOWS FROM FINANCING ACTIVITIES:
  Net proceeds from stock issuances.......................       --            3,734,076      3,997,800       --            --
  Exercise of stock options...............................       --             --               25,816       --             12,500
  Proceeds from capital leases and short-term debt........      1,825,746        700,065        845,238       126,193       171,031
  Principal payments under capital lease obligations and
   other indebtedness.....................................       (673,714)      (456,991)      (678,135)     (147,664)     (215,210)
  Proceeds from line of credit............................       --            1,000,000      1,200,000       250,000       --
  Payments on line of credit..............................       --             --           (1,500,000)      --           (700,000)
  Net proceeds from sale of convertible notes.............      1,038,607       --             --             --            --
                                                            -------------  -------------  -------------  ------------  ------------
      Net cash provided by (used in) financing
       activities.........................................      2,190,639      4,977,150      3,890,719       228,529      (731,679)
                                                            -------------  -------------  -------------  ------------  ------------
      Net increase (decrease) in cash and cash
       equivalents........................................     (1,809,617)       630,211      1,302,372      (363,335)   (1,824,450)
CASH AND CASH EQUIVALENTS, beginning
 of period................................................      3,002,330      1,192,713      1,822,924     1,822,924     3,125,296
                                                            -------------  -------------  -------------  ------------  ------------
CASH AND CASH EQUIVALENTS, end of period..................  $   1,192,713  $   1,822,924  $   3,125,296  $  1,459,589  $  1,300,846
                                                            -------------  -------------  -------------  ------------  ------------
                                                            -------------  -------------  -------------  ------------  ------------
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
  Cash paid for interest..................................  $      75,997  $     237,620  $     262,896  $     61,699  $     50,013
  Cash paid for income taxes..............................       --             --        $      18,000  $    --       $      6,000
SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING AND FINANCING ACTIVITIES:
1993 -- Return of laboratory equipment in the amount of $152,500, included in accounts receivable.
1994 -- Conversion of convertible promissory notes into Series D Preferred Stock in the amount of
        $1,075,940, including accrued interest.
</TABLE>
 
   The accompanying notes are an integral part of these financial statements.
 
                                      F-6
<PAGE>
                                  UROCOR, INC.
                         NOTES TO FINANCIAL STATEMENTS
 
1.  THE COMPANY:
    UroCor,  Inc.  ("the  Company"),  a Delaware  corporation,  operates  in one
business segment  and  provides a  broad  range of  diagnostic  and  information
services  and expects to provide therapeutic  products to urologists and managed
care organizations across the U.S. The  Company assists its customers to  better
manage patients with urological cancers and other complex urological diseases.
 
2.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:
    (A)  USE OF  ESTIMATES.   The preparation  of these  financial statements in
conformity with generally accepted accounting principles requires management  to
make estimates and assumptions that affect the amounts reported in the financial
statements  and  accompanying  notes.  Actual results  could  differ  from those
estimates.
 
    (B) CASH AND CASH FLOW REPORTING.   The Company considers all highly  liquid
debt  instruments purchased with a  maturity of three months  or less to be cash
equivalents. The fair value of such  instruments equals their net book value  at
December 31, 1995.
 
    (C)  PROPERTY AND  EQUIPMENT.   Property and  equipment are  stated at cost.
Equipment under capital leases is stated  at the present value of minimum  lease
payments at the inception of the lease.
 
    Depreciation  on property and  equipment is calculated  on the straight-line
basis over  the estimated  useful  lives of  the  assets. Equipment  held  under
capital  leases and  leasehold improvements  are amortized  on the straight-line
basis over the shorter of the remaining  lease term or the economic useful  life
of the asset.
 
    In  1995, the Financial Accounting Standards  Board issued Statement No. 121
"Accounting for the Impairment of Long-Lived Assets and for Long-Lived Assets to
be disposed of".  The Company adopted  the standard  in 1995 with  no impact  on
their financial position or results of operations.
 
    (D)  SOFTWARE DEVELOPMENT COSTS.  Certain internal costs related to software
development relating to  the Company's information  services are capitalized  as
property  and equipment  when incurred.  Capitalization begins  when the project
reaches technological  feasibility and  ceases  when the  product is  ready  for
release. Amortization of capitalized software development costs is provided over
the  estimated economic  life of  the software,  generally two  years, using the
straight-line method.  Software  development  costs are  reviewed  annually  for
impairment.  Software development costs  capitalized during 1993,  1994 and 1995
were $0, $0  and $35,000, respectively.  Capitalized software development  costs
capitalized in the three months ended March 31, 1996, were $57,501 (unaudited).
 
    (E)  INTANGIBLE AND OTHER ASSETS.   The Company has  acquired or applied for
options, licenses, patents  and distribution rights  for various diagnostic  and
therapeutic  technologies  or products.  The costs  related  to such  rights are
capitalized and  included in  intangible and  other assets  in the  accompanying
balance sheets. Such costs are amortized over the estimated economic life of the
related technologies or products.
 
    (F)    RESEARCH  AND  DEVELOPMENT.   Research  and  development  is directed
in-house by the  Company, as  well as off-premises  under various  collaborative
arrangements  and studies. Such costs are  expensed as incurred. At December 31,
1995, the Company  had commitments totaling  approximately $447,000 for  various
sponsored research and collaborative arrangements through 1997.
 
    (G)  INCOME TAXES.  The Company accounts for income taxes under Statement of
Financial Accounting Standards ("SFAS") No.  109 "Accounting for Income  Taxes".
Under  the provisions of SFAS No. 109, deferred income taxes are recorded, where
appropriate, to reflect the estimated future tax effects of differences  between
financial statement and tax bases of assets and liabilities.
 
                                      F-7
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
2.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES: (CONTINUED)
    (H)  REVENUE.  Revenue is recognized when  products are sold or services are
rendered. Revenue subject to Medicare or third-party reimbursement are  recorded
at estimated reimbursable amounts. The Company receives a significant portion of
its  revenues from tests performed principally for beneficiaries of the Medicare
program. In 1993, 1994 and 1995,  approximately 56%, 58% and 58%,  respectively,
of  the Company's  revenues were  derived from  tests performed  principally for
beneficiaries of the Medicare program. For the three months ended March 31, 1995
and 1996,  approximately 57%  and 53%  of the  Company's revenues  were  derived
similarly  from the Medicare program (unaudited).  Under law and regulation, for
most of the tests performed for Medicare beneficiaries, the Company must  accept
reimbursement  allowed by Medicare as payment  in full. Substantially all of the
Company's current  services  receive reimbursement  at  various rates  or  on  a
case-by-case basis. The Company is not aware of any material claims, disputes or
unresolved matters relating to Medicare or other third-party payors.
 
    (I)   NET INCOME (LOSS) PER COMMON  SHARE AND COMMON SHARE EQUIVALENTS.  Net
income (loss) per common  share and common share  equivalents has been  computed
based  upon  the  weighted average  number  of  common shares  and  common share
equivalents outstanding during each  period. Common share equivalents  recognize
the  potential dilutive effects  of the conversion of  preferred stock to common
stock and the impact of outstanding options and warrants to acquire common stock
using the treasury stock method and the Company's estimate of the fair value  of
common  stock at  each year  end. Pursuant  to the  rules of  the Securities and
Exchange Commission, common and common share equivalent shares issued in the  12
months  prior to March 29, 1996, have been included in the computation of common
and common  equivalent  shares as  if  they  were outstanding  for  all  periods
presented,  including loss years  where the impact of  the incremental shares is
antidilutive. All other  common stock  equivalents have been  excluded from  the
computations  for 1993 and 1994 because their impact on the Company's net income
(loss) per share is antidilutive.
 
    (J)   ACCRUED  COMPENSATION.   Accrued  compensation consists  of  quarterly
commissions  for  sales  representative  commissions  (usually  paid  the  month
following the quarter's  end), bonus accruals  for non-sales personnel  (usually
paid annually during the second quarter), and reccurring monthly accruals.
 
    (K)   UNAUDITED  INTERIM  FINANCIAL  INFORMATION.    The  unaudited  interim
financial information as of  March 31, 1995  and 1996 and  for the three  months
then  ended  has  been prepared  on  the  same basis  as  the  audited financial
statements. In the  opinion of management,  such unaudited information  includes
all  adjustments  (consisting  only  of  normal  recurring  accruals) considered
necessary for a fair presentation of this interim information. Operating results
for the three months ended March 31, 1996 are not necessarily indicative of  the
results  that may be expected  for any other interim  period or any other future
fiscal year.
 
3.  PROPERTY AND EQUIPMENT:
    Property and equipment, stated at cost, are summarized as follows:
 
<TABLE>
<CAPTION>
                                                              1994            1995
                                                         --------------  --------------  MARCH 31, 1996
                                                                                         ---------------
                                                                                           (UNAUDITED)
<S>                                                      <C>             <C>             <C>
Laboratory equipment...................................  $    1,298,069  $    1,606,846   $   1,683,883
Computer equipment and software........................       1,119,937       1,586,961       1,914,857
Office furniture, equipment and improvements...........         721,452       1,064,970       1,186,711
                                                         --------------  --------------  ---------------
                                                              3,139,458       4,258,777       4,785,451
Less -- Accumulated depreciation and amortization......      (1,172,419)     (1,815,040)     (2,058,360)
                                                         --------------  --------------  ---------------
                                                         $    1,967,039  $    2,443,737   $   2,727,091
                                                         --------------  --------------  ---------------
                                                         --------------  --------------  ---------------
</TABLE>
 
                                      F-8
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
3.  PROPERTY AND EQUIPMENT: (CONTINUED)
    The depreciable lives for property and equipment are as follows:
 
<TABLE>
<CAPTION>
                                                                                                YEARS
                                                                                             -----------
<S>                                                                                          <C>
Laboratory equipment.......................................................................  3.5 to 5
Computer equipment and software............................................................  3.5 to 5
Office furniture, equipment and improvements...............................................  3.5 to 10
</TABLE>
 
4.  INTANGIBLE AND OTHER ASSETS:
    Intangible and other assets consist of the following:
 
<TABLE>
<CAPTION>
                                                              1994           1995
                                                          -------------  -------------  MARCH 31, 1996
                                                                                        ---------------
                                                                                          (UNAUDITED)
<S>                                                       <C>            <C>            <C>
Licenses, options, patents and trademarks...............  $     166,069  $     320,026   $     331,056
Less -- Accumulated amortization........................       --               (3,000)         (4,250)
                                                          -------------  -------------  ---------------
Net intangible assets...................................        166,069        317,026         326,806
Distribution agreement (Note 7).........................        750,000      1,250,000       1,250,000
Deposits and other......................................        137,680        176,696         261,636
                                                          -------------  -------------  ---------------
                                                          $   1,053,749  $   1,743,722   $   1,838,442
                                                          -------------  -------------  ---------------
                                                          -------------  -------------  ---------------
</TABLE>
 
5.  LINE OF CREDIT:
    In March 1994, the Company obtained a $1.5 million line of credit secured by
accounts receivable and  a lien  on all  other tangible  assets, which  excludes
equipment  under capital leases, of the Company. The total amount outstanding on
the line of credit was  $700,000 at December 31, 1995,  which is reflected as  a
non-current  liability  in  the accompanying  balance  sheets.  Average balances
outstanding under this line of credit  have been $1,000,000 and $882,000  during
1994  and 1995, with an  average interest rate of  9.2% and 10.58% respectively.
Interest is paid monthly at  prime (8.75% at December  31, 1995) plus 1.75%.  In
February  1996 this line of credit was extended to February 1997 and expanded to
$3.0 million at an interest rate of prime plus 1.5%. The fair value of the  line
of credit equals the net book value at December 31, 1995. Under the terms of the
line  of  credit agreement,  the Company  must  comply with  certain restrictive
covenants.
 
6.  LEASES:
    The Company is obligated under  capital lease agreements that expire  during
the next four years. At December 31, 1994 and 1995, the gross amount of property
and  equipment and  related amortization  recorded under  capital leases  was as
follows:
 
<TABLE>
<CAPTION>
                                                              1994            1995
                                                          -------------  --------------  MARCH 31, 1996
                                                                                         --------------
                                                                                          (UNAUDITED)
<S>                                                       <C>            <C>             <C>
Laboratory equipment....................................  $   1,129,587  $    1,490,575   $  1,534,684
Computer equipment......................................        655,305         913,639        927,392
Office furniture and equipment..........................        296,268         629,304        742,623
                                                          -------------  --------------  --------------
                                                              2,081,160       3,033,518      3,204,699
Less -- Accumulated depreciation and amortization.......       (621,396)     (1,337,647)    (1,548,896)
                                                          -------------  --------------  --------------
                                                          $   1,459,764  $    1,695,871   $  1,655,803
                                                          -------------  --------------  --------------
                                                          -------------  --------------  --------------
</TABLE>
 
    The  Company  also  has   noncancelable  operating  leases  for   laboratory
facilities, office space and equipment that expire over the next ten years, with
options  to extend.  Rental expense for  operating leases during  1993, 1994 and
1995 approximated $157,000, $236,000 and $352,000, respectively.
 
                                      F-9
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
6.  LEASES: (CONTINUED)
    Future minimum lease commitments as of December 31, 1995 are:
 
<TABLE>
<CAPTION>
                                                                               CAPITAL       OPERATING
                                                                               LEASES         LEASES
                                                                            -------------  -------------
<S>                                                                         <C>            <C>
1996......................................................................  $   1,015,400  $     455,477
1997......................................................................        594,894        490,504
1998......................................................................        352,107        529,235
1999......................................................................        133,124        587,018
2000......................................................................       --              624,518
Thereafter (laboratory and office space to 2005)..........................       --            3,497,814
                                                                            -------------  -------------
Total minimum lease payments..............................................      2,095,525  $   6,184,566
                                                                                           -------------
                                                                                           -------------
Less -- Amount representing interest......................................       (268,952)
                                                                            -------------
Total obligations under capital leases....................................      1,826,573
Less -- Current installments of obligations under capital leases..........       (860,088)
                                                                            -------------
Obligation under capital leases, net of current installments..............  $     966,485
                                                                            -------------
                                                                            -------------
</TABLE>
 
    In June  1995, the  Company consolidated  all of  its operations,  research,
marketing  and administrative functions  into a new  building constructed by and
leased from a shareholder of  the Company. The Company's  10 year lease on  this
facility   covers  48,000  square  feet  initially  with  options  available  on
additional space  up to  the entire  110,000 square  feet of  the building.  The
monthly rentals are included in the operating lease commitments above.
 
    In  March 1996,  the Company  received a commitment  for a  new $1.5 million
lease financing arrangement for capital expenditures through March 1997.
 
7.  COMMITMENTS AND CONTINGENCIES:
    (A) DISTRIBUTION  AGREEMENT.   In  connection  with a  product  distribution
agreement  covering a product currently undergoing regulatory review by the U.S.
Food  and  Drug  Administration  ("FDA"),   the  Company  made  payments  to   a
manufacturer  of $750,000  and $500,000  in 1994  and 1995,  respectively. These
payments, totaling $1,250,000 are included  in intangible and other assets,  net
in  the accompanying balance sheets at December  31, 1994 and 1995 (see Note 4).
The Company will be required to make a milestone payment of $1,750,000 when  and
if regulatory approval by the FDA is received. If the product is not approved by
the  FDA within a specified time period, the manufacturer must repay the Company
an amount equivalent to all amounts previously paid by the Company.
 
    The aggregate  payments of  $3.0 million  to be  paid under  the  agreement,
assuming  FDA approval, will be amortized over the expected economic life of the
distribution agreement, based on expected future unit sales of the product.  The
Company  anticipates that it will assume  that the agreement will extend through
the initial term  of five years  and the renewal  term of five  years, but  will
revise the amortization period if events support shortening the period.
 
    Assuming  and upon approval of  the product by the  FDA, the Company will be
required to conduct specified sales, marketing and certain other activities with
respect to the product and meet  certain minimum unit sales levels. The  initial
term  of the distribution  agreement is for  five years, and  the Company has an
option to renew for an additional five  years, at no cost, if the minimum  sales
levels are attained.
 
    (B)  EMPLOYMENT  AGREEMENTS.   Certain  key  employees of  the  Company have
entered into arrangements  regarding their  terms of employment.  While none  of
such arrangements provide for fixed
 
                                      F-10
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
7.  COMMITMENTS AND CONTINGENCIES: (CONTINUED)
periods  of employment, they do provide for continued payment of salaries for up
to six  months following  termination without  cause, aggregating  approximately
$378,000 at December 31, 1995 and March 31, 1996 (unaudited).
 
8.  RELATED PARTY TRANSACTIONS:
    The  Company had certain transactions  for contractual services performed by
members of the  Board of  Directors or their  affiliates which  are included  in
expenses  of approximately $71,000, $59,000 and  $42,000 in 1993, 1994 and 1995,
respectively. In addition, the Company recognized rent expense totaling $167,000
related to the new facility which is leased from a shareholder (see Note 6).  In
management's  opinion, these transactions were  conducted on terms equivalent to
those with unrelated third parties.
 
9.  STOCKHOLDERS' EQUITY:
    CONVERTIBLE PREFERRED STOCK, CLASS A STOCK AND CLASS B STOCK. The  Company's
convertible preferred stock consists of the following:
 
<TABLE>
<S>                                                                                  <C>
1991 Series A, $.01 par value, authorized, issued and outstanding 1,199,999 shares
Series B, $.01 par value, authorized, issued and outstanding 1,467,608 shares in
 1994 and 1995
Series B1, $.01 par value, authorized 1,467,608 shares; no shares issued and
 outstanding
Series C, $.01 par value, authorized, issued and outstanding 981,071 shares in 1994
 and 1995
Series C1, $.01 par value, authorized 981,071 shares; no shares issued and
 outstanding
Series D, $.01 par value, authorized 1,500,000 shares in 1994 and 1,154,397 shares
 in 1995; issued and outstanding 1,154,397 shares in 1994 and 1995
Series D1, $.01 par value, authorized 1,500,000 shares in 1994 and 1,154,397 shares
 in 1995; no shares issued and outstanding in 1994 and 1995
Series E/EG, $.01 par value, authorized, no shares issued and outstanding in 1994;
 issued and outstanding 823,320 shares in 1995
Series E1/EG1, $.01 par value, authorized 823,320; no shares issued and outstanding
 in 1994 and 1995
Series I, $.01 par value, authorized, issued and outstanding 80,000 shares in 1994
 and 1995
</TABLE>
 
    In  March  1996,  the  Company  restated  its  Certificate  of Incorporation
changing the authorized shares of  preferred stock from 10,132,791 to  6,000,000
and the authorized shares of Class A Stock from 590,674 to 513,093.
 
    SERIES D PREFERRED STOCK AND CONVERTIBLE PROMISSORY NOTES.  In October 1993,
several existing stockholders of the Company purchased 8% Convertible Promissory
Notes from the Company resulting in total proceeds to the Company of $1,038,607.
Effective  March 30,  1994, in  connection with  the sale  of 849,094  shares of
Series D Preferred Stock at $4.30 per share, the 8% Convertible Promissory Notes
were converted into 250,224 shares of Series D Preferred Stock. In April 1994, a
secondary closing on sales  of Series D Preferred  Stock was completed with  the
sale of 55,079 shares at $4.30 per share. The aggregate proceeds from the Series
D Preferred Stock offerings totaled $4,963,885, with cash proceeds of $3,887,945
and  $1,075,940  from  conversion of  the  8% Convertible  Promissory  Notes and
related accrued interest, resulting in net proceeds of $4,798,870.
 
                                      F-11
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
9.  STOCKHOLDERS' EQUITY: (CONTINUED)
    Upon conversion of the 8%  Convertible Promissory Notes as discussed  above,
the  Company agreed to execute and deliver to the 8% Convertible Promissory Note
purchasers stock warrants to  purchase 130,232 shares of  Common Stock at  $4.30
per share, exercisable through October 1998.
 
    SERIES  E AND SERIES EG  PREFERRED STOCK.  In  June 1995, the Company closed
offerings of Series E and Series  EG preferred stock totaling 823,320 shares  at
$5.00  per share. In connection with  this offering, the Company issued warrants
to purchase 164,664 shares of Common Stock  with an exercise price of $5.00  per
share.  These warrants expire after five years. The net proceeds from the Series
E and Series EG preferred stock offering totaled $3,997,800.
 
    The significant attributes of  each class or series  of stock are  described
below:
 
    (A) CONVERSION.
 
        (I)  AUTOMATIC  CONVERSION.    Each  outstanding  share  of  Convertible
    Preferred Stock and Class  A Stock and Class  B Stock will automatically  be
    converted  into  Common Stock  upon the  closing  of an  underwritten public
    offering. In addition, in the event of a liquidation, dissolution, merger or
    sale of the Company, in which the market valuation of the Company equals  or
    exceeds  $46,220,397, all Class A Stock will automatically be converted into
    Common Stock.
 
    In the  event of  a  new stock  offering  at a  per  share price  below  the
respective  conversion price of Series B, Series C, Series D, Series E or Series
EG Preferred Stock,  each share of  Series B, Series  C, Series D,  Series E  or
Series  EG  Preferred Stock  held by  a  party not  participating in  such stock
offering will automatically convert to one share of Series B1, Series C1, Series
D1, Series E1 or Series EG1 Preferred Stock, as applicable.
 
        (II) OPTIONAL CONVERSION.  Convertible Preferred Stock is convertible at
    the option of the holder, at any time, into shares of Common Stock.
 
        (III) CONVERSION  SHARES.   The  per share  conversion factors  will  be
    ratably  adjusted  to reflect  any changes  in capital  stock such  as stock
    dividends, combinations  or reclassifications.  At  December 31,  1995,  all
    Convertible  Preferred  Stock,  Class  A  Stock  and  Class  B  Stock shares
    outstanding were convertible to an equivalent number of Common Stock shares,
    except that the 981,071 shares of Series C Preferred Stock were  convertible
    into 1,177,277 shares of Common Stock.
 
    (B)  LIQUIDATION.   Upon  dissolution below  certain specified  or aggregate
proceeds, liquidation  or sale,  merger  or other  disposition of  the  Company,
stockholders will receive distribution of proceeds as described below:
 
        (I)  FIRST PREFERENCE.  Holders of Convertible Preferred Stock and Class
    A Stock will  first receive  preference to Common  Stock and  Class B  Stock
    holders.  The holders of Convertible Preferred  Stock and Class A Stock will
    receive declared but unpaid dividends plus the following amount per share:
 
    - $.25 per share for Class A Stock;
 
    - $1.25 per share for 1991 Series A and Series I Preferred Stock;
 
    - $1.55 per share for Series B and Series B1 Preferred Stock;
 
    - $3.25 per share for Series C and Series C1 Preferred Stock;
 
    - $4.30 per share for Series D and D1 Preferred Stock; and
 
    - $5.00 per  share  for Series  E,  Series E1,  Series  EG, and  Series  EG1
      Preferred.
 
                                      F-12
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
9.  STOCKHOLDERS' EQUITY: (CONTINUED)
    If  proceeds are insufficient to permit payment in full, as described above,
then the holders of these  shares will share ratably  in proportion to the  full
amounts otherwise distributable.
 
        (II)  SECOND PREFERENCE.  If the  first preference amounts are satisfied
    in full, remaining proceeds will then be distributed to the holders of Class
    A Stock as  follows: the lesser  of (i)  $1,683,396 or (ii)  26% of  amounts
    remaining available for distribution.
 
    If  proceeds are  insufficient to  permit payment  in full  of the secondary
preference amounts,  then the  holders of  these shares  will share  ratably  in
proportion to the full amount otherwise distributable.
 
        (III)  GENERAL  DISTRIBUTION.    Upon satisfying  the  First  and Second
    Preference requirements, all holders of stock will then share ratably in any
    remaining proceeds, on a basis as  if converted to Common Stock. All  shares
    will  convert  to  Common  Stock  except  in  the  event  of  a liquidation,
    dissolution, merger or sale of the Company, in which the market valuation of
    the Company equals or exceeds $46,220,397,  then after the first and  second
    preference   distributions  described  above,  any  holders  of  Convertible
    Preferred Stock would not participate in the general distribution  described
    above. In such a liquidation, dissolution, merger or sale, the Class A Stock
    would  be automatically converted into Common  Stock and therefore would not
    participate in the first and second preferences described above.
 
    (C) REDEMPTION.  All series of convertible preferred stock excluding  Series
EG  and EG1, were originally  issued with redemption rights.  In March 1996, the
shareholders of these convertible preferred shares relinquished their redemption
rights  pursuant  to  the  Company's  plans  for  an  initial  public  offering.
Accordingly  all  convertible preferred  stock is  classified  as equity  in the
accompanying balance sheet at par value.
 
    COMMON STOCK.   At December 31,  1995, the Company  had 8,700,000 shares  of
Common Stock authorized for the conversion of Convertible Preferred Stock, Class
A  Stock, Class B Stock  and the exercise of  Common Stock options and warrants.
The total Common Stock shares that would have been issued assuming conversion of
all series and  classes of  stock and  exercise of  options and  warrants as  of
December  31,  1995  was 8,020,202.  In  March  1996, the  Company  restated its
Certificate of Incorporation changing the authorized shares of Common Stock from
8,700,000 shares to 20,000,000 shares.
 
    WARRANTS.   There  are a  total  of  486,310 warrants  outstanding  for  the
purchase  of the  Company's common stock  exercisable at  prices ranging between
$1.25 to $5.50 per share  and expiring from October 1998  to May 2001. No  value
was attributed to these warrants in connection with their issuances. At December
31,  1995, none of these warrants had  been exercised. A summary of the warrants
outstanding is presented below:
 
<TABLE>
<CAPTION>
                                                                                                             MARCH 31, 1996
                                   1993                       1994                      1995                  (UNAUDITED)
                        --------------------------  ------------------------  ------------------------  ------------------------
                                       EXERCISE                   EXERCISE                  EXERCISE                  EXERCISE
                                       PRICE PER                  PRICE PER                 PRICE PER                 PRICE PER
                         WARRANTS        SHARE       WARRANTS       SHARE      WARRANTS       SHARE      WARRANTS       SHARE
                        -----------  -------------  -----------  -----------  -----------  -----------  -----------  -----------
<S>                     <C>          <C>            <C>          <C>          <C>          <C>          <C>          <C>
Outstanding, beginning
 of year..............      85,600     $    1.25        85,600   $      1.25     321,646   $1.25 - 5.50    486,310   $1.25 - 5.50
Granted...............      --                         236,046   4.30 - 5.50     164,664          5.00      --           --
Exercised.............      --                          --                        --                        --           --
                        -----------                 -----------               -----------               -----------
Outstanding, end of
 year.................      85,600     $    1.25       321,646   $1.25 - 5.50    486,310   $1.25 - 5.50    486,310   $1.25 - 5.50
                        -----------                 -----------               -----------               -----------
                        -----------                 -----------               -----------               -----------
</TABLE>
 
                                      F-13
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
10. STOCK OPTION PLAN:
    The Company has adopted a stock  option plan, the "1992 Stock Option  Plan".
The  Company accounts  for this plan  under APB  Opinion No. 25,  under which no
compensation cost  has  been  recognized,  except for  the  stock  option  grant
described below. Under the Plan 1,400,000 shares of common stock are reserved as
incentive and non-qualified options for employees and officers and non-qualified
options  for directors and independent contractors of the Company. These options
vest over three  to five  years, expire  ten years  after issuance  and have  an
exercise  price equal to the stock's estimated  fair market value on the date of
grant.
 
    A summary of the status of the plan is presented below:
 
<TABLE>
<CAPTION>
                                                                                                   MARCH 31, 1996
                                 1993                   1994                    1995                (UNAUDITED)
                        ----------------------  ---------------------  ----------------------  ----------------------
                                    EXERCISE                EXERCISE               EXERCISE                EXERCISE
                                    PRICE PER              PRICE PER                 PRICE                   PRICE
                         SHARES       SHARE      SHARES      SHARE      SHARES     PER SHARE    SHARES     PER SHARE
                        ---------  -----------  ---------  ----------  ---------  -----------  ---------  -----------
<S>                     <C>        <C>          <C>        <C>         <C>        <C>          <C>        <C>
Outstanding, beginning
 of period............     80,000   $.35 - .75    284,000  $.35 -  .75   706,994  $.35 - 1.25    982,344  $.35 - 1.75
Granted...............    204,000   .35 - .75     423,494  .75 - 1.25    403,250  1.25 - 1.75     --          --
Exercised.............     --                      --                    (69,188)  .35 -  .75    (12,500)        1.00
Expired...............     --                        (500)        .75    (58,712)  .35 - 1.50    (10,250)  .75 - 1.50
                        ---------               ---------              ---------               ---------
Outstanding, end of
 period...............    284,000   $.35 - .75    706,994  $.35 - 1.25   982,344  $.35 - 1.75    959,594   .35 - 1.75
                        ---------               ---------              ---------               ---------
                        ---------               ---------              ---------               ---------
Exercisable, end of
 period...............     78,990   $.35 - .75    269,320  $.35 - 1.25   341,870  $.35 - 1.75    353,580   .35 - 1.75
                        ---------               ---------              ---------               ---------
                        ---------               ---------              ---------               ---------
</TABLE>
 
    In December 1995, the Company  issued options to employees covering  295,000
shares  of Common Stock.  Considering the Company's  anticipated public offering
price per share and other events,  the Company estimated that the adjusted  fair
value  of the Common  Stock at the date  of grant of  these options exceeded the
exercise price of the options.  Accordingly, the Company will recognize  imputed
compensation   expenses  as   a  noncash   charge  to   operations,  aggregating
approximately $443,000 over the actual vesting period of these options of  three
to five years.
 
    In  1995, the Financial Accounting Standards  Board issued Statement No. 123
"Accounting for  Stock -  Based Compensation".  This Statement  requires  either
changing  accounting methods to recognize the fair value of stock options issued
as compensation expense in  the financial statements,  or disclosing the  effect
that  such change would have  had on the financial  statements. The Company will
adopt Statement No. 123 in 1996 and has elected to only provide the  disclosures
required  by  the statement.  Thus, there  will  be no  effect on  the Company's
financial position.
 
11. EMPLOYEE BENEFIT PLAN:
    The  Company  has  established  a  401(k)  employee  benefit  plan  covering
substantially  all  employees. The  Plan  is funded  through  voluntary employee
salary deferrals. Although the Company has the discretion to make  contributions
to the Plan, no such amounts have been contributed to date.
 
                                      F-14
<PAGE>
                                  UROCOR, INC.
                   NOTES TO FINANCIAL STATEMENTS (CONTINUED)
 
12. INCOME TAXES:
    The tax effects of the temporary differences which gave rise to deferred tax
assets and liabilities at December 31, 1994 and 1995 were:
 
<TABLE>
<CAPTION>
                                                                                1994           1995
                                                                            -------------  -------------
<S>                                                                         <C>            <C>
Code Section 481 adjustment related to change to accrual method of
 accounting...............................................................  $    (355,022) $    (236,681)
Assets and liabilities related to capitalized leases, net.................         78,236         49,667
Depreciation and amortization.............................................         55,400        (17,889)
Allowance for doubtful accounts...........................................       --             (117,961)
Alternative minimum tax carryforward......................................       --               24,000
Net operating loss........................................................      3,644,867      3,642,906
                                                                            -------------  -------------
Net deferred tax asset (liability)........................................      3,423,481      3,344,042
Valuation allowance.......................................................     (3,423,481)    (3,320,042)
                                                                            -------------  -------------
    Total net deferred tax asset..........................................  $    --        $      24,000
                                                                            -------------  -------------
                                                                            -------------  -------------
</TABLE>
 
    At  December  31,  1995, the  Company  had  regular tax  net  operating loss
carryforwards of approximately $13,700,000 which  will begin to expire in  2002.
The  Company's income tax provision differed from the federal statutory rate due
to the utilization  of the Company's  tax net operating  loss carryforward.  The
annual utilization of this carryforward will be limited by Internal Revenue Code
Section  382 due to the  fact a cumulative change in  ownership of more than 50%
has previously occurred. Therefore, the future utilization of this net operating
loss carryforward will be limited to approximately $9,600,000.
 
    A valuation allowance against the net deferred tax asset has been  recorded,
except  for the amount attributable to  the alternative minimum tax credit which
can be carried forward indefinitely,  on the basis that significant  uncertainty
exists  regarding the  realizability of such  assets. The deferred  tax asset is
included in other assets in the accompanying balance sheets.
 
                                      F-15
<PAGE>
- -------------------------------------------
                                     -------------------------------------------
- -------------------------------------------
                                     -------------------------------------------
 
    NO  DEALER, SALESPERSON,  OR OTHER  PERSON HAS  BEEN AUTHORIZED  TO GIVE ANY
INFORMATION OR  TO MAKE  ANY REPRESENTATIONS  IN CONNECTION  WITH THIS  OFFERING
OTHER  THAN THOSE  CONTAINED IN  THIS PROSPECTUS,  AND, IF  GIVEN OR  MADE, SUCH
INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED
BY THE COMPANY OR THE UNDERWRITERS. THIS PROSPECTUS DOES NOT CONSTITUTE AN OFFER
TO SELL OR  A SOLICITATION  OF AN  OFFER TO BUY  ANY SECURITIES  OTHER THAN  THE
SHARES OF COMMON STOCK TO WHICH IT RELATES OR AN OFFER TO, OR A SOLICITATION OF,
ANY  PERSON  IN  ANY JURISDICTION  WHERE  SUCH  OFFER OR  SOLICITATION  WOULD BE
UNLAWFUL. NEITHER THE DELIVERY  OF THIS PROSPECTUS NOR  ANY SALE MADE  HEREUNDER
SHALL,  UNDER ANY  CIRCUMSTANCES, CREATE AN  IMPLICATION THAT THERE  HAS BEEN NO
CHANGE IN  THE  AFFAIRS  OF THE  COMPANY  SINCE  THE DATE  HEREOF  OR  THAT  THE
INFORMATION  CONTAINED HEREIN IS CORRECT  AS OF ANY TIME  SUBSEQUENT TO THE DATE
HEREOF.
 
                             ----------------------
 
                               TABLE OF CONTENTS
                             ----------------------
 
<TABLE>
<CAPTION>
                                                    PAGE
                                                    -----
<S>                                              <C>
PROSPECTUS SUMMARY.............................           3
RISK FACTORS...................................           5
THE COMPANY....................................          14
USE OF PROCEEDS................................          14
DIVIDEND POLICY................................          14
CAPITALIZATION.................................          15
DILUTION.......................................          16
SELECTED FINANCIAL DATA........................          17
MANAGEMENT'S DISCUSSION AND ANALYSIS OF
 FINANCIAL CONDITION AND RESULTS OF
 OPERATIONS....................................          18
BUSINESS.......................................          24
MANAGEMENT.....................................          36
CERTAIN TRANSACTIONS...........................          41
SECURITY OWNERSHIP OF MANAGEMENT AND PRINCIPAL
 STOCKHOLDERS..................................          42
DESCRIPTION OF CAPITAL STOCK...................          44
SHARES ELIGIBLE FOR FUTURE SALE................          47
UNDERWRITING...................................          49
LEGAL MATTERS..................................          50
EXPERTS........................................          50
AVAILABLE INFORMATION..........................          50
INDEX TO FINANCIAL STATEMENTS..................         F-1
</TABLE>
 
                             ----------------------
 
    UNTIL                  ,  1996 (25 DAYS AFTER THE DATE OF THIS  PROSPECTUS),
ALL  DEALERS EFFECTING TRANSACTIONS IN THE  COMMON STOCK OFFERED HEREBY, WHETHER
OR NOT  PARTICIPATING  IN  THIS  DISTRIBUTION, MAY  BE  REQUIRED  TO  DELIVER  A
PROSPECTUS.  THIS  DELIVERY  REQUIREMENT IS  IN  ADDITION TO  THE  OBLIGATION OF
DEALERS TO DELIVER A PROSPECTUS WHEN ACTING AS UNDERWRITERS AND WITH RESPECT  TO
THEIR UNSOLD ALLOTMENTS OR SUBSCRIPTIONS.
 
                                2,800,000 SHARES
 
                                     [LOGO]
                                  COMMON STOCK
 
                              -------------------
 
                                   PROSPECTUS
 
                              -------------------
                             MONTGOMERY SECURITIES
 
                             VOLPE, WELTY & COMPANY
                                           , 1996
 
- -------------------------------------------
                                     -------------------------------------------
- -------------------------------------------
                                     -------------------------------------------
<PAGE>
                                    PART II
                     INFORMATION NOT REQUIRED IN PROSPECTUS
 
ITEM 13.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.
 
    The estimated expenses in connection with the Offering are:
 
<TABLE>
<S>                                                                        <C>
Securities and Exchange Commission Registration Fee......................  $  11,104
NASD Filing Fee..........................................................      3,720
Nasdaq National Market Listing Fee.......................................     40,000
Legal Fees and Expenses..................................................    200,000
Accounting Fees and Expenses.............................................    100,000
Blue Sky Fees and Expenses (including legal fees)........................     15,000
Printing Expenses........................................................    150,000
Transfer Agent and Registrar Fees........................................      5,000
Miscellaneous............................................................     75,176
                                                                           ---------
  TOTAL..................................................................  $ 600,000
                                                                           ---------
                                                                           ---------
</TABLE>
 
ITEM 14.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.
 
    Article  X of  the Company's  Amended and  Restated By-laws  (the "By-laws")
provides for  mandatory  indemnification to  at  least the  extent  specifically
allowed  by Section 145 of the General  Corporation Law of the State of Delaware
(the "GCL").
 
    Pursuant to  Section 145  of the  GCL,  UroCor generally  has the  power  to
indemnify  its  current and  former  directors, officers,  employees  and agents
against expenses and liabilities incurred by them in connection with any suit to
which they are, or threatened to be made, a party by reason of their serving  in
such  positions  so long  as  they acted  in  good faith  and  in a  manner they
reasonably believed to  be in,  or not  opposed to,  the best  interests of  the
Company,  and with respect to any criminal  action, they had no reasonable cause
to believe their conduct was lawful. With respect to suits by or in the right of
the Company, however,  indemnification is generally  limited to attorneys'  fees
and  other expenses and is not available if such person is adjudged to be liable
to the Company unless the court determines that indemnification is  appropriate.
The statute expressly provides that the power to indemnify authorized thereby is
not  exclusive  of  any  rights  granted under  any  bylaw,  agreement,  vote of
stockholders or disinterested directors, or otherwise. The Company also has  the
power to purchase and maintain insurance for such persons.
 
    The  above discussion of the Company's By-laws and Section 145 of the GCL is
not intended to be exhaustive and is  qualified in its entirety by each of  such
documents and such statute.
 
    The  Company has entered into indemnification agreements with its directors,
executive officers and certain key employees that generally obligate the Company
to indemnify such persons to the extent permitted under the GCL.
 
    Reference is  made to  the  form of  the  Underwriting Agreement,  filed  as
Exhibit   1.1  to  be   filed  by  amendment,   which  contains  provisions  for
indemnification of  the Company,  its directors,  officers and  any  controlling
persons   by  the  Underwriters  against  certain  liabilities  for  information
furnished by the Underwriters.
 
ITEM 15.  RECENT SALES OF UNREGISTERED SECURITIES.
 
    Since January  1,  1993, UroCor  has  sold unregistered  securities  in  the
amounts,  at  the time  and for  the aggregate  amounts of  consideration listed
below. With respect to sales  of Preferred Stock and  Class A stock, all  shares
and  amounts and per share prices described  below have been adjusted to reflect
the automatic conversion of such shares  into Common Stock immediately prior  to
the  closing of  the Offering  and a five-to-one  stock split  effected in March
1993. The securities were sold to  purchasers directly by the Company, and  such
sales did not involve any underwriter. The Company considers these securities to
have  been offered and sold in transactions not involving a public offering and,
therefore, to
 
                                      II-1
<PAGE>
be exempted  from  registration under  Section  4(2)  and Regulation  D  of  the
Securities  Act of 1933, as amended. For  equity securities, the "Type" of stock
listed in the table below reflects the class or series of stock actually issued,
however, the  number  of shares  has  been  adjusted to  reflect  the  automatic
conversion  of such shares into Common Stock immediately prior to the closing of
the Offering.
 
<TABLE>
<CAPTION>
                                                                                    AGGREGATE
                                                                                    AMOUNT OF
                                                                                    SECURITIES      AGGREGATE
             PURCHASER                         TYPE                  DATE             ISSUED      CONSIDERATION
- ------------------------------------  ----------------------  ------------------  --------------  -------------
<S>                                   <C>                     <C>                 <C>             <C>
Investor Group (1)..................     Promissory Notes     October 1993        $  1,038,607     $ 1,038,607
Investor Group (2)..................    Series D Preferred    March/April 1994       1,154,397     $ 4,963,885
Investor Group (1)..................         Warrants         March 1994                      (3)          N/A
Investor Group (4)..................    Series E Preferred    June 1995                763,320     $ 3,816,600
Investor Group (5)..................   Series EG Preferred    June 1995                 60,000     $   300,000
Investor Group (4)(5)...............         Warrants         June 1995                       (6)          N/A
Various Employees and a Director
 Through Exercise of Options Granted                          From January 1993
 Under 1992 Stock Option Plan.......       Common Stock       through April 1996        82,288     $    38,765
Silicon Valley Bank.................         Warrant          April 1994                      (7)          N/A
Bank of Oklahoma....................         Warrant          April 1994                      (8)          N/A
IAF Biovac, Inc.....................         Warrant          December 1994                   (9)          N/A
</TABLE>
 
- --------------------------
(1) The investor group consists of  Concord Partners II, L.P.; Concord  Partners
    Japan  Limited; PB-SB 1985 Investment Partnership VII; The Woodlands Venture
    Fund,  L.P.;  Salomon  Brothers  Holding  Company,  Inc.;  WestMed   Venture
    Partners;  ML Oklahoma  Venture Partners,  Limited Partnership; Presbyterian
    Health  Foundation;   Rovent  Limited   Partnership;  Advent   International
    Investors  Limited Partnership;  Advent Omnibus  Limited Partnership; Advent
    S.B.P.E. Limited  Partnership;  Gateway  Venture Partners  II,  L.P.;  Marco
    Investment  Company;  Floyd E.  Farha; William  M.  and Lu  Beard Charitable
    Remainder Trust; and Stanton L. Young.
 
(2) The investor group consists of  Concord Partners II, L.P.; Concord  Partners
    Japan  Limited; PB-SB 1985 Investment Partnership VII; The Woodlands Venture
    Fund,  L.P.;  Salomon  Brothers  Holding  Company,  Inc.;  WestMed   Venture
    Partners;  ML Oklahoma  Venture Partners,  Limited Partnership; Presbyterian
    Health  Foundation;   Rovent  Limited   Partnership;  Advent   International
    Investors  Limited Partnership;  Advent Omnibus  Limited Partnership; Advent
    S.B.P.E. Limited  Partnership;  Gateway  Venture Partners  II,  L.P.;  Marco
    Investment  Company;  Floyd E.  Farha; William  M.  and Lu  Beard Charitable
    Remainder Trust; Stanton L. Young;  Lexington Partners III, L.P.;  Lexington
    Partners  IV, L.P.; Dillon,  Read & Co. Inc.,  as Agent; Kummell Investments
    Limited; and Dean A. McGee Eye Institute Endowment Fund.
 
(3) The aggregate number of shares of Common Stock issuable upon exercise of the
    warrants is 130,232, subject to certain antidilution adjustments.
 
(4) The investor group consists of GMI/DRI Investment Trust; Dillon, Read &  Co.
    Inc.,  as Agent;  Concord Partners  II, L.P.;  Lexington Partners  IV, L.P.;
    Kummell Investments Limited; WestMed Venture Partners; Smith Barney Inc., as
    custodian for the benefit of Floyd E. Farha IRA Rollover; Floyd E. Farha; W.
    M. and  Lu  Beard  Charitable Remainder  Trust;  Marco  Investment  Company;
    Stanton L. Young; and The Health Care and Biotechnology Fund.
 
(5) The investor group consists of Gateway Partners L.P.
 
(6) The aggregate number of shares of Common Stock issuable upon exercise of the
    warrants is 164,664, subject to certain antidilution adjustments.
 
(7)  The number of shares of Common  Stock issuable upon exercise of the warrant
    is 4,942, subject to certain antidilution adjustments.
 
(8) The number of shares of Common  Stock issuable upon exercise of the  warrant
    is 872, subject to certain antidilution adjustments.
 
(9)  The number of shares of Common  Stock issuable upon exercise of the warrant
    is 100,000, subject to certain antidilution adjustments.
 
                                      II-2
<PAGE>
ITEM 16.  EXHIBITS AND FINANCIAL STATEMENT SCHEDULES.
 
    (a)  Exhibits:
 
<TABLE>
<CAPTION>
   NO.                                                         DESCRIPTION
- ---------             ---------------------------------------------------------------------------------------------
<C>        <C>        <S>
    1.1           --  Form of Underwriting Agreement.
    3.1*          --  Restated Certificate of Incorporation.
    3.2*          --  Amended and Restated By-laws.
    4.1           --  Form of Common Stock Certificate.
    4.2*          --  See Exhibits numbered 3.1 and 3.2 for provisions of the Restated Certificate of Incorporation
                       and Amended and  Restated By-laws of  UroCor defining the  rights of the  holders of  Common
                       Stock.
    5.1           --  Opinion of Fulbright & Jaworski L.L.P.
   10.1*          --  The UroCor, Inc. Amended and Restated 1992 Stock Option Plan.
   10.2*          --  Distribution Agreement, dated December 30, 1994, between IAF BioVac Inc. and UroCor, Inc. and
                       letter  agreement  dated  December  30,  1994, between  IAF  BioVac  Inc.  and  UroCor, Inc.
                       (Confidential Treatment requested pursuant to Rule 406 under the Securities Act).
   10.3*          --  Loan Agreement, dated March 14, 1994, between Silicon Valley Bank and CytoDiagnostics,  Inc.,
                       as modified by Loan Modification Agreement dated June 13, 1994 between CytoDiagnostics, Inc.
                       and  Silicon  Valley Bank,  and Loan  Modification  Agreement dated  March 9,  1995, between
                       Silicon Valley  Bank and  UroCor, Inc.  and as  amended by  Amendment to  Loan and  Security
                       Agreement dated February 1, 1996, between Silicon Valley Bank and UroCor, Inc.
   10.4*          --  Lease  Agreement, dated  April 15, 1994,  between Presbyterian Health  Foundation and UroCor,
                       Inc.
   10.5*          --  Employment Agreement, dated January 1, 1990, between William A. Hagstrom and UroCor, Inc.
   10.6*          --  Employment Agreement, dated April 23, 1990, between Mark Dimitroff and UroCor, Inc.
   10.7*          --  Employment Agreement, dated September 4, 1990, between Robert Veltri and UroCor, Inc.
   10.8*          --  Employment Agreement, dated June 1, 1992, between Socrates Choumbakos and UroCor, Inc.
   10.9*          --  Form of Indemnification Agreement between UroCor, Inc.  and each of the individuals named  in
                       Schedule 10.9 thereto.
   10.10*         --  1995 Management Incentive Compensation Plan.
   10.11*         --  Registration  Rights Agreement, dated June  2, 1995, among UroCor,  Inc. and the stockholders
                       named therein.
   10.12*         --  Master Equipment Lease, dated May 17, 1995, between Financing for Science International, Inc.
                       and UroCor, Inc.,  Commitment Letter  dated March 18,  1996, between  Financing for  Science
                       International, Inc. and UroCor, Inc. and Amendment Letter dated April 17, 1996, by Financing
                       for Science International, Inc.
   10.13*         --  Master  Lease Agreement, dated June 26, 1993,  between Linc Capital Management Services, Ltd.
                       and CytoDiagnostics, Inc., as amended  by Addendum No. 001  to Master Lease Agreement  dated
                       June  26, 1993,  between Linc Capital  Management Services, Ltd.  and CytoDiagnostics, Inc.,
                       Addendum No.  002 to  Master  Lease Agreement  dated July  19,  1993, between  Linc  Capital
                       Management  Services,  Ltd. and  CytoDiagnostics,  Inc., Addendum  No.  003 to  Master Lease
                       Agreement dated  October  8,  1993,  between Linc  Capital  Management  Services,  Ltd.  and
                       CytoDiagnostics,  Inc. and  Addendum No.  004 to Master  Lease Agreement  dated December 22,
                       1994, between Linc Capital Management Services, Ltd. and UroCor, Inc.
</TABLE>
 
                                      II-3
<PAGE>
<TABLE>
<CAPTION>
   NO.                                                         DESCRIPTION
- ---------             ---------------------------------------------------------------------------------------------
   10.14          --  Employment Agreement, dated April 5, 1996, between Kathryn L.W. Ingerly and UroCor, Inc.
<C>        <C>        <S>
   11.1*          --  Statement re Computation of Per Share Earnings.
   23.1           --  Consent of Arthur Andersen LLP.
   23.2           --  Consent of Fulbright & Jaworski L.L.P. (included in Exhibit 5.1).
   24.1*          --  Powers of Attorney from certain members of the Board of Directors of the Company.
</TABLE>
 
- ------------------------
* Previously filed.
+ To be filed by amendment.
 
    As permitted by Item 601(b)(4) of Regulation S-K, the Company has not  filed
with  this  Registration Statement  certain instruments  defining the  rights of
holders of long-term debt of  the Company, if any,  because the total amount  of
securities  authorized under any of such instruments  does not exceed 10% of the
total assets of the Company.  The Company agrees to furnish  a copy of any  such
agreements to the Securities and Exchange Commission upon request.
 
    (b) Financial Statement Schedules:
 
        Schedule II -- Valuation and Qualifiying Accounts
 
ITEM 17.  UNDERTAKINGS.
 
    Insofar  as indemnification for liabilities arising under the Securities Act
may be permitted to directors, officers  and controlling persons of the  Company
pursuant to the foregoing provisions, or otherwise, the Company has been advised
that   in  the   opinion  of  the   Securities  and   Exchange  Commission  such
indemnification is against public policy as expressed in the Securities Act  and
is,  therefore, unenforceable.  In the  event that  a claim  for indemnification
against such liabilities  (other than  the payment  by the  Company of  expenses
incurred  or paid by a director, officer or controlling person of the Company in
the successful defense of  any action, suit or  proceeding) is asserted by  such
director,  officer or controlling person in connection with the securities being
registered, the Company will,  unless in the opinion  of its counsel the  matter
has  been settled  by controlling  precedent, submit  to a  court of appropriate
jurisdiction the question whether such  indemnification by it is against  public
policy  as expressed  in the Securities  Act and  will be governed  by the final
adjudication of such issue.
 
    The undersigned Company hereby undertakes to provide to the Underwriters  at
the  closing  specified  in  the  Underwriting  Agreement  certificates  in such
denominations and registered in  such names as required  by the Underwriters  to
permit prompt delivery to each purchaser.
 
    The undersigned Company hereby undertakes that:
 
        (1)  For purposes of determining any liability under the Securities Act,
    the information omitted from the form of prospectus filed as a part of  this
    Registration Statement in reliance upon Rule 430A and contained in a form of
    prospectus  filed by the Company pursuant to Rule 424(b)(1) or (4) or 497(h)
    under the Securities Act shall be deemed  to be a part of this  Registration
    Statement as of the time it was declared effective.
 
        (2)  For the purpose  of determining any  liability under the Securities
    Act, each post-effective amendment that contains a form of prospectus  shall
    be  deemed to  be a  new registration  statement relating  to the securities
    offered therein, and the offering of  such securities at that time shall  be
    deemed to be the initial bona fide offering thereof.
 
                                      II-4
<PAGE>
                                   SIGNATURES
 
    Pursuant  to the requirements  of the Securities Act,  UroCor, Inc. has duly
caused this Amendment No. 1 to Registration Statement to be signed on its behalf
by the undersigned,  thereunto duly authorized,  in the City  of Oklahoma  City,
State of Oklahoma, on May 10, 1996.
 
                                                       UroCor, Inc.
 
                                          By:       /s/ WILLIAM A. HAGSTROM
 
                                            ------------------------------------
                                                    William A. Hagstrom
                                              CHAIRMAN OF THE BOARD, PRESIDENT
                                                AND CHIEF EXECUTIVE OFFICER
 
    Pursuant  to the requirements of the Securities Act, this Amendment No. 1 to
Registration Statement has  been signed below  by the following  persons in  the
capacities and on the dates indicated.
 
<TABLE>
<CAPTION>
                      SIGNATURE                                            TITLE                            DATE
- ------------------------------------------------------  --------------------------------------------  -----------------
 
<S>                                                     <C>                                           <C>
               /s/ WILLIAM A. HAGSTROM                   Chairman of the Board, President and Chief        May 10, 1996
     -------------------------------------------           Executive Officer (Principal Executive
                 William A. Hagstrom                                      Officer)
 
              /s/ SOCRATES H. CHOUMBAKOS                Vice President Corporate Development, Chief        May 10, 1996
     -------------------------------------------         Financial Officer and Secretary (Principal
                Socrates H. Choumbakos                               Financial Officer)
 
               /s/ MICHAEL N. MCDONALD                   Director of Finance and Administration and        May 10, 1996
     -------------------------------------------          Treasurer (Principal Accounting Officer)
                 Michael N. McDonald
 
                          *                                               Director                         May 10, 1996
     -------------------------------------------
                 Paul A. Brown, M.D.
 
                          *                                               Director                         May 10, 1996
     -------------------------------------------
                  Herbert J. Conrad
 
                /s/ MICHAEL E. HERBERT                                    Director                         May 10, 1996
     -------------------------------------------
                  Michael E. Herbert
 
                          *                                               Director                         May 10, 1996
     -------------------------------------------
               Louis M. Sherwood, M.D.
 
                       /s/ DON E. SPYRISON                                Director                         May 10, 1996
     -------------------------------------------
                   Don E. Spyrison
 
                          *                                               Director                         May 10, 1996
     -------------------------------------------
                    Joe D. Tippens
 
         *By:      /s/ SOCRATES H. CHOUMBAKOS
        --------------------------------------
 Socrates H. Choumbakos, ATTORNEY-IN-FACT FOR EACH OF
                THE PERSONS INDICATED
</TABLE>
 
                                      II-5
<PAGE>
                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS
 
To the Board of Directors of
UroCor, Inc.:
 
    We  have audited in  accordance with generally  accepted auditing standards,
the financial statements of UroCor, Inc. included in this registration statement
and have issued our report thereon dated March 29, 1996. Our audit was made  for
the  purpose of forming an opinion on  the basic financial statements taken as a
whole. The schedule listed in the index of financial statements is presented for
purposes of complying with the Securities and Exchange Commission's rules and is
not part of the basic financial statements. This schedule has been subjected  to
the  auditing procedures applied in the  audit of the basic financial statements
and, in our opinion, fairly states  in all material respects the financial  data
required  to be set forth therein in  relation to the basic financial statements
taken as a whole.
 
Oklahoma City, Oklahoma,                  ARTHUR ANDERSEN LLP
March 29, 1996
 
                                      S-1
<PAGE>
                                                                     SCHEDULE II
 
                                  UROCOR, INC.
                       VALUATION AND QUALIFYING ACCOUNTS
 
<TABLE>
<CAPTION>
                                                                         ADDITIONS
                                                                 --------------------------
                                                                  CHARGE TO     CHARGE TO
                                                     BEGINNING    COST AND        OTHER                     ENDING
                   DESCRIPTION                        BALANCE      EXPENSE      ACCOUNTS     DEDUCTION(1)   BALANCE
- --------------------------------------------------  -----------  -----------  -------------  ------------  ---------
<S>                                                 <C>          <C>          <C>            <C>           <C>
For the Year Ended December 31, 1995:
  Allowance for Doubtful Accounts.................     670,845      934,482        --           (623,281)    982,046
 
For the Year Ended December 31, 1994:
  Allowance for Doubtful Accounts.................     392,522      706,074        --           (427,751)    670,845
 
For the Year Ended December 31, 1993:
  Allowance for Doubtful Accounts.................     204,530      496,264        --           (308,272)    392,522
</TABLE>
 
- ------------------------
(1) Represents write-offs  of  uncollectible  accounts  receivable  against  the
    allowance for doubtful accounts.
 
                                      S-2
<PAGE>
                               INDEX TO EXHIBITS
 
<TABLE>
<CAPTION>
 EXHIBITS                                                                                                       PAGE
- -----------                                                                                                   ---------
<C>          <S>                                                                                              <C>
      1.1    Form of Underwriting Agreement.
      3.1*   Restated Certificate of Incorporation.
      3.2*   Amended and Restated By-laws.
      4.1    Form of Common Stock Certificate.
      4.2*   See Exhibits numbered 3.1 and 3.2 for provisions of the Restated Certificate of Incorporation
              and Amended and Restated By-laws of UroCor defining the rights of the holders of Common Stock.
      5.1    Opinion of Fulbright & Jaworski L.L.P.
     10.1*   The UroCor, Inc. Amended and Restated 1992 Stock Option Plan.
     10.2*   Distribution Agreement, dated December 30, 1994, between IAF BioVac Inc. and UroCor, Inc. and
              letter agreement dated December 30, 1994, between IAF BioVac Inc. and UroCor, Inc.
              (Confidential Treatment requested pursuant to Rule 406 under the Securities Act).
     10.3*   Loan Agreement, dated March 14, 1994, between Silicon Valley Bank and CytoDiagnostics, Inc., as
              modified by Loan Modification Agreement dated June 13, 1994 between CytoDiagnostics, Inc. and
              Silicon Valley Bank, and Loan Modification Agreement dated March 9, 1995, between Silicon
              Valley Bank and UroCor, Inc., and as amended by Amendment to Loan and Security Agreement dated
              February 1, 1996, between Silicon Valley Bank and UroCor, Inc.
     10.4*   Lease Agreement, dated April 15, 1994, between Presbyterian Health Foundation and UroCor, Inc.
     10.5*   Employment Agreement, dated January 1, 1990, between William A. Hagstrom and UroCor, Inc.
     10.6*   Employment Agreement, dated April 23, 1990, between Mark Dimitroff and UroCor, Inc.
     10.7*   Employment Agreement, dated September 4, 1990, between Robert Veltri and UroCor, Inc.
     10.8*   Employment Agreement, dated June 1, 1992, between Socrates Choumbakos and UroCor, Inc.
     10.9*   Form of Indemnification Agreement between UroCor, Inc. and each of the individuals named in
              Schedule 10.9 thereto.
     10.10*  1995 Management Incentive Compensation Plan.
     10.11*  Registration Rights Agreement, dated June 2, 1995, among UroCor, Inc. and the stockholders
              named therein.
     10.12*  Master Equipment Lease, dated May 17, 1995, between Financing for Science International, Inc.
              and UroCor, Inc., Commitment Letter dated March 18, 1996, between Financing for Science
              International, Inc. and UroCor, Inc. and Amendment Letter dated April 17, 1996, by Financing
              for Science International, Inc.
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBITS                                                                                                       PAGE
- -----------                                                                                                   ---------
     10.13*  Master Lease Agreement, dated June 26, 1993, between Linc Capital Management Services, Ltd. and
              CytoDiagnostics, Inc., as amended by Addendum No. 001 to Master Lease Agreement dated June 26,
              1993, between Linc Capital Management Services, Ltd. and CytoDiagnostics, Inc., Addendum No.
              002 to Master Lease Agreement dated July 19, 1993, between Linc Capital Management Services,
              Ltd. and CytoDiagnostics, Inc., Addendum No. 003 to Master Lease Agreement dated October 8,
              1993, between Linc Capital Management Services, Ltd. and CytoDiagnostics, Inc. and Addendum
              No. 004 to Master Lease Agreement dated December 22, 1994, between Linc Capital Management
              Services, Ltd. and UroCor, Inc.
<C>          <S>                                                                                              <C>
     10.14   Employment Agreement, dated April 5, 1996, between Kathryn L.W. Ingerly and UroCor, Inc.
     11.1*   Statement re Computation of Per Share Earnings.
     23.1    Consent of Arthur Andersen LLP.
     23.2    Consent of Fulbright & Jaworski L.L.P. (included in Exhibit 5.1).
     24.1*   Powers of Attorney from certain members of the Board of Directors of the Company.
</TABLE>
 
- ------------------------
* Previously filed.
 
+ To be filed by amendment.

<PAGE>
                                2,800,000 SHARES
                                  UROCOR, INC.
                                  COMMON STOCK
                             UNDERWRITING AGREEMENT
 
May   , 1996
 
MONTGOMERY SECURITIES
VOLPE, WELTY & COMPANY
  As Representatives of the several Underwriters
c/o MONTGOMERY SECURITIES
600 Montgomery Street
San Francisco, California 94111
 
Dear Sirs:
 
    SECTION  1.    INTRODUCTORY.   UroCor,  Inc.,  a  Delaware  corporation (the
"Company"), proposes to issue  and sell 2,800,000 shares  of its authorized  but
unissued shares of Common Stock, $0.01 par value per share (the "Common Stock"),
to   the  several  underwriters   named  in  Schedule   A  annexed  hereto  (the
"Underwriters"), for whom you are  acting as Representatives. Said aggregate  of
2,800,000  shares of Common Stock are herein called the "Firm Common Shares." In
addition, the  Company  proposes to  grant  to  the Underwriters  an  option  to
purchase  up to 420,000 additional shares  of Common Stock (the "Optional Common
Shares"), as provided in Section  4 hereof. The Firm  Common Shares and, to  the
extent  such option  is exercised,  the Optional  Common Shares  are hereinafter
collectively referred to as the "Common Shares."
 
    You have advised the Company that the Underwriters propose to make a  public
offering of their respective portions of the Common Shares on the effective date
of  the registration statement hereinafter referred to, or as soon thereafter as
in your judgment is advisable.
 
    The Company hereby confirms its agreements  with respect to the purchase  of
the Common Shares by the Underwriters as follows:
 
    SECTION  2.   REPRESENTATIONS AND  WARRANTIES OF  THE COMPANY.   The Company
hereby represents and warrants to the several Underwriters that:
 
        (a) A  registration  statement on  Form  S-1 (Reg.  No.  333-3182)  with
    respect to the Common Shares has been prepared by the Company in conformity,
    in  all material  respects, with the  requirements of the  Securities Act of
    1933, as amended (the "Act"), and the rules and regulations (the "Rules  and
    Regulations")  of the Securities and  Exchange Commission (the "Commission")
    thereunder, and has been filed with the Commission. The Company has prepared
    and has  filed or  proposes to  file prior  to the  effective date  of  such
    registration  statement  an  amendment or  amendments  to  such registration
    statement, which  amendment or  amendments have  been or  will be  similarly
    prepared.  There  have  been delivered  to  you  two signed  copies  of such
    registration statement  and amendments,  together with  two copies  of  each
    exhibit filed therewith. Conformed copies of such registration statement and
    amendments  (but without exhibits) and of the related preliminary prospectus
    have been  delivered  to you  in  such  quantities as  you  reasonably  have
    requested  for each of the Underwriters. The Company will next file with the
    Commission one  of  the  following:  (i)  prior  to  effectiveness  of  such
    registration  statement, a further amendment  thereto, including the form of
    final prospectus, (ii) a final prospectus in accordance with Rules 430A  and
    424(b) of the Rules and Regulations or (iii) a term sheet (the "Term Sheet")
    as described in and in accordance with Rules 434 and 424(b) of the Rules and
    Regulations.  As filed, the  final prospectus, if  one is used,  or the Term
    Sheet and  Preliminary  Prospectus  (as hereinafter  defined),  if  a  final
    prospectus  is  not  used,  shall  include  all  Rule  430A  Information (as
    hereinafter defined)  and, except  to the  extent that  you shall  agree  in
    writing to a modification, shall be in all
<PAGE>
    substantive respects in the form furnished to you prior to the date and time
    that this Agreement was executed and delivered by the parties hereto, or, to
    the  extent not  completed at  such date and  time, shall  contain only such
    specific additional information and other changes (beyond that contained  in
    the  latest  Preliminary Prospectus)  as the  Company shall  have previously
    advised you in writing would be included or made therein.
 
    The term "Registration Statement" as used in this Agreement shall mean  such
    registration  statement  at  the time  such  registration  statement becomes
    effective and, in  the event  any post-effective  amendment thereto  becomes
    effective  prior to the  First Closing Date  (as hereinafter defined), shall
    also mean such registration statement as so amended; provided, however, that
    such term shall  also include  (i) all Rule  430A Information  deemed to  be
    included  in  such  registration  statement at  the  time  such registration
    statement becomes  effective as  provided  by Rule  430A  of the  Rules  and
    Regulations  and (ii) any registration statement filed pursuant to 462(b) of
    the  Rules  and  Regulations  relating  to  the  Common  Shares.  The   term
    "Preliminary  Prospectus" shall mean any  preliminary prospectus referred to
    in the preceding paragraph  and any preliminary  prospectus included in  the
    Registration Statement at the time it becomes effective that omits Rule 430A
    Information.  The term  "Prospectus" as  used in  this Agreement  shall mean
    either (i) the prospectus relating to the Common Shares in the form in which
    it is first filed with the Commission  pursuant to Rule 424(b) of the  Rules
    and  Regulations or, (ii) if a Term Sheet is not used and no filing pursuant
    to Rule 424(b) of the Rules and Regulations is required, shall mean the form
    of final prospectus included in the Registration Statement at the time  such
    registration  statement becomes effective or (iii)  if a Term Sheet is used,
    the Term Sheet in the  form in which it is  first filed with the  Commission
    pursuant  to Rule  424(b) of  the Rules  and Regulations,  together with the
    Preliminary Prospectus included in the Registration Statement at the time it
    becomes effective. The term "Rule  430A Information" means information  with
    respect  to  the Common  Shares  and the  offering  thereof permitted  to be
    omitted from the Registration Statement  when it becomes effective  pursuant
    to Rule 430A of the Rules and Regulations.
 
        (b) The Commission has not issued any order preventing or suspending the
    use  of  any Preliminary  Prospectus,  and each  Preliminary  Prospectus has
    conformed in all material  respects to the requirements  of the Act and  the
    Rules  and Regulations  and, as  of its  date, has  not included  any untrue
    statement of a material fact or  omitted to state a material fact  necessary
    to  make the  statements therein,  in the  light of  the circumstances under
    which they  were made,  not misleading;  and at  the time  the  Registration
    Statement  becomes effective, and at all  times subsequent thereto up to and
    including  each  Closing  Date   hereinafter  mentioned,  the   Registration
    Statement  and the  Prospectus, and  any amendments  or supplements thereto,
    will contain all material statements and information required to be included
    therein by the Act and  the Rules and Regulations  and will in all  material
    respects  conform  to  the  requirements  of  the  Act  and  the  Rules  and
    Regulations, and neither the Registration Statement nor the Prospectus,  nor
    any  amendment or supplement thereto, will include any untrue statement of a
    material fact or omit to state a material fact required to be stated therein
    or  necessary  to  make  the  statements  therein,  in  the  light  of   the
    circumstances under which they were made, not misleading; provided, however,
    no  representation or  warranty contained in  this subsection  2(b) shall be
    applicable to  information  contained in  or  omitted from  any  Preliminary
    Prospectus, the Registration Statement, the Prospectus or any such amendment
    or  supplement in reliance  upon and in  conformity with written information
    furnished to the  Company by or  on behalf of  any Underwriter, directly  or
    through  the  Representatives,  specifically  for  use  in  the  preparation
    thereof.
 
        (c) The Company  does not own  or control, directly  or indirectly,  any
    corporation,  association  or  other  entity.  The  Company  has  been  duly
    incorporated and is validly existing as a corporation in good standing under
    the laws of the State of  Delaware, with full corporate power and  authority
    to own and lease its properties and conduct its business as described in the
    Prospectus;  the Company is in possession  of and operating in compliance in
    all material respects with all authorizations, licenses, permits,  consents,
    certificates   and  orders  material   to  the  conduct   of  its  business,
 
                                       2
<PAGE>
    all of which are  valid and in  full force and effect;  the Company is  duly
    qualified to do business and is in good standing as a foreign corporation in
    each  jurisdiction in  which the ownership  or leasing of  properties or the
    conduct  of   its  business   requires   such  qualification,   except   for
    jurisdictions  in which the failure to so  qualify would not have a material
    adverse effect upon the  Company; and no proceeding  has been instituted  in
    any  such  jurisdiction, revoking,  limiting  or curtailing,  or  seeking to
    revoke, limit or curtail, such power and authority or qualification.
 
        (d) At the time of the  First Closing, the Company will have  authorized
    and outstanding capital stock as set forth under the heading "Description of
    Capital  Stock" in  the Prospectus,  subject to  any changes  resulting from
    exercises of outstanding  options under the  Company's Amended and  Restated
    1992  Stock Option Plan (the "1992  Plan") and forfeiture of options granted
    under the 1992 Plan; the issued and outstanding shares of Common Stock  have
    been  duly authorized and validly issued,  are fully paid and nonassessable,
    have been issued in compliance with  all federal and state securities  laws,
    were not issued in violation of or subject to any preemptive rights or other
    rights  to  subscribe  for  or  purchase  securities,  and  conform  to  the
    description  thereof  contained   in  the  Prospectus   under  the   heading
    "Description  of Capital Stock."  Except as disclosed  in the Prospectus and
    the financial  statements of  the Company,  and the  related notes  thereto,
    included in the Prospectus, and except for options that may be granted under
    the  1992 Plan, the Company  has no outstanding options  to purchase, or any
    preemptive rights  or other  rights to  subscribe for  or to  purchase,  any
    securities  or obligations convertible into, or any contracts or commitments
    to issue or sell, shares of its  capital stock or any such options,  rights,
    convertible  securities  or obligations.  The  description of  the Company's
    stock option  plan and  the options  granted and  exercised thereunder,  set
    forth  in the  Prospectus, accurately and  fairly presents,  in all material
    respects,  the  information  required  under  the  Act  and  the  Rules  and
    Regulations to be shown with respect to such plan and options.
 
        (e)  The  Common  Shares have  been  duly authorized  and,  when issued,
    delivered and paid for in  the manner set forth  in this Agreement, will  be
    duly  authorized,  validly issued,  fully paid  and nonassessable,  and will
    conform to the  description thereof  contained in the  Prospectus under  the
    heading "Description of Capital Stock." No preemptive rights or other rights
    to  subscribe for or purchase exist with respect to the issuance and sale of
    the Common Shares by the Company pursuant to this Agreement. No  stockholder
    of  the  Company has  any right  which has  not been  waived to  require the
    Company to register the sale of  any shares owned by such stockholder  under
    the  Act in the  public offering contemplated by  this Agreement. No further
    approval or authority of the stockholders  or the Board of Directors of  the
    Company  will be required for the issuance  and sale of the Common Shares to
    be sold by the Company as contemplated herein.
 
        (f) The Company has all requisite corporate power and authority to enter
    into this Agreement and perform  the transactions contemplated hereby.  This
    Agreement  has been duly  authorized, executed and  delivered by the Company
    and constitutes a valid and binding obligation of the Company in  accordance
    with  its  terms,  except as  enforceability  may be  limited  by applicable
    equitable   principles   or    by   bankruptcy,   insolvency,    moratorium,
    reorganization  or similar laws from  time to time in  effect relating to or
    affecting the  enforcement of  creditors' rights  generally and  by  general
    equitable   principles  (regardless   of  whether   such  enforceability  is
    considered  in  a  proceeding  in  equity   or  at  law)  and  except   that
    enforceability of the rights to indemnity and contribution contained in this
    Agreement  may  be  limited  by  federal or  state  laws  and  public policy
    underlying such laws. The  making and performance of  this Agreement by  the
    Company  and the consummation  of the transactions  herein contemplated will
    not violate any provisions of the Restated Certificate of Incorporation (the
    "Certificate of Incorporation")  or the  amended and  restated by-laws  (the
    "By-laws")  of the Company, and will not conflict with, result in the breach
    or violation  of, or  constitute, either  by itself  or upon  notice or  the
    passage  of time or both,  a default under any  agreement, mortgage, deed of
    trust, lease, franchise, license, indenture,  permit or other instrument  to
    which  the  Company  is a  party  or by  which  the  Company or  any  of its
    properties may be bound  or affected (except  for such conflicts,  breaches,
    violations or defaults,
 
                                       3
<PAGE>
    which, in the aggregate, would not materially adversely affect the financial
    condition,  properties, business, results of  operations or prospects of the
    Company), any statute or any authorization, judgment, decree, order, rule or
    regulation of any  court or  any regulatory body,  administrative agency  or
    other  governmental body applicable to the Company or any of its properties.
    No consent, approval, authorization or other order of any court,  regulatory
    body,  administrative agency or other governmental  body is required for the
    execution and  delivery  of  this  Agreement  or  the  consummation  of  the
    transactions  contemplated by this Agreement, except for compliance with the
    Act, the  Blue Sky  laws applicable  to the  public offering  of the  Common
    Shares  by the several Underwriters and  the clearance of such offering with
    the National Association of Securities Dealers, Inc. (the "NASD").
 
        (g) Arthur  Andersen  L.L.P.,  who have  expressed  their  opinion  with
    respect  to the financial statements and  schedule filed with the Commission
    as a part of the Registration  Statement and included in the Prospectus  and
    in  the Registration Statement,  are independent accountants  as required by
    the Act and the Rules and Regulations.
 
        (h) The  financial  statements and  schedule  of the  Company,  and  the
    related  notes  thereto,  included  in the  Registration  Statement  and the
    Prospectus present fairly, in all material respects, the financial  position
    of  the Company as of the respective  dates of such financial statements and
    schedules, and the results of  operations and changes in financial  position
    of  the Company for the respective periods covered thereby. Such statements,
    schedule and related notes have  been prepared in accordance with  generally
    accepted  accounting principles applied on a consistent basis as reported on
    by the independent accountants named in subsection 2(g). No other  financial
    statements  or schedules  are required  to be  included in  the Registration
    Statement. The selected financial data set forth in the Prospectus under the
    captions "Capitalization" and "Selected  Financial Data" present fairly,  in
    all material respects, the information set forth therein on the basis stated
    in the Registration Statement.
 
        (i)  Except as  disclosed in the  Prospectus, and except  as to defaults
    which individually or in the aggregate would not be material to the Company,
    the Company  is  not  in  violation  or default  of  any  provision  of  its
    Certificate  of Incorporation or By-laws, or other organizational documents,
    or is  in  breach  of or  default  with  respect to  any  provision  of  any
    agreement,   judgment,  decree,  order,  mortgage,  deed  of  trust,  lease,
    franchise, license, indenture, permit or other  instrument to which it is  a
    party  or by which  it or any of  its properties are  bound (except for such
    breaches or defaults which in  the aggregate would not materially  adversely
    affect  the financial condition, properties, business, results of operations
    or prospects of the Company);  and there does not  exist any state of  facts
    which  constitutes an event of default on the part of the Company as defined
    in such documents  or which, with  notice or  lapse of time  or both,  would
    constitute  such an  event of  default (except  for such  events of default,
    which in the aggregate would  not materially adversely affect the  financial
    condition, business, results of operations or prospects of the Company).
 
        (j)   There are no contracts or other documents required to be described
    in the Registration Statement or to be filed as exhibits to the Registration
    Statement by the Act  or by the  Rules and Regulations  which have not  been
    described  or filed as  required. All such  contracts are in  full force and
    effect on the  date hereof; and  neither the Company  nor, to the  Company's
    knowledge,  any other  party is in  breach of  or default under  any of such
    contracts.
 
        (k) Other than  as disclosed in  the Prospectus, there  are no legal  or
    governmental  actions,  suits or  proceedings pending  or, to  the Company's
    judgment, decree  or order  of any  court, regulatory  body,  administrative
    agency or other governmental body, to which the Company os or may be a party
    or,  to the Company's  knowledge, of which  property owned or  leased by the
    Company  is  or  may  be  the  subject,  or  related  to  environmental   or
    discrimination   matters,  which  actio,  suits,  proceedings,  injunctions,
    judgments, decrees  or  orders  might, individually  or  in  the  aggregate,
    prevent  or adversely affect the transactions contemplated by this Agreement
    or  result  in  a  material  adverse  effect  on  the  financial  condition,
    properties, business, results of operations
 
                                       4
<PAGE>
    or  prospects  of the  Company; and,  to the  Company's knowledge,  no labor
    disturbances by the employees of the Company exists or is threatened,  which
    might  be expected to affect  adversely the financial condition, properties,
    business, results of operations or prospects of the Company.
 
        (l) The Company has good and marketable title to all the properties  and
    assets  reflected as owned in the financial statements hereinabove described
    (or elsewhere  in the  Prospectus), subject  to no  lien, mortgage,  pledge,
    charge  or encumbrance of  any kind except  (i) those, if  any, reflected in
    such financial statements (or  elsewhere in the  Prospectus), or (ii)  those
    which  are not material in  amount and do not  adversely affect the use made
    and proposed to be made of such  property by the Company. The Company  holds
    its  leased properties under valid and  binding leases, with such exceptions
    as are  not  materially significant  in  relation  to the  business  of  the
    Company.  Except as disclosed in the  Prospectus, the Company owns or leases
    all such properties as are necessary  to its operations as now conducted  or
    as disclosed in the Prospectus as proposed to be conducted.
 
        (m)  Since the respective dates as of  which information is given in the
    Registration Statement  and  Prospectus,  and except  as  described  in  the
    Prospectus:  (i) the  Company has not  incurred any  material liabilities or
    obligations, indirect, direct  or contingent, or  entered into any  material
    oral  or written agreement or other transaction which is not in the ordinary
    course of business  or which  could result in  a material  reduction in  the
    future  earnings  of the  Company; (ii)  the Company  has not  sustained any
    material loss or  interference with  its business or  properties from  fire,
    flood,  windstorm, accident  or other  calamity, whether  or not  covered by
    insurance; (iii) the Company has not paid or declared any dividends or other
    distributions with respect to  its capital stock and  the Company is not  in
    default  in the  payment of  principal or  interest on  any outstanding debt
    obligations; (iv) there has not been any change in the capital stock  (other
    than  upon  the  sale of  the  Common  Shares hereunder,  the  conversion of
    convertible securities into  shares of  Common Stock, the  grant of  options
    under  the 1992 Plan, and upon the exercise of options and warrants, each as
    described in the  Registration Statement)  or indebtedness  material to  the
    Company  (other than in the ordinary course  of business); and (v) there has
    not been any material adverse  change in the financial condition,  business,
    properties, results of operations or prospects of the Company.
 
        (n)  Except  as  disclosed  in  the  Prospectus,  (i)  the  Company  has
    sufficient trademarks,  trade names,  patent rights,  copyrights,  licenses,
    approvals  and governmental  authorizations to  conduct its  business as now
    conducted; (ii)  the  expiration  of any  trademarks,  trade  names,  patent
    rights, copyrights, licenses, approvals or governmental authorizations would
    not  have a  material adverse effect  on the  financial condition, business,
    results of operations or prospects of the Company; and (iii) the Company has
    no knowledge of any material infringement by it of any trademark, trade name
    rights, patent rights,  mask works,  copyrights, licenses,  trade secret  or
    other  similar  rights of  others, and  no claim  has been  made or,  to the
    Company's knowledge,  has been  threatened,  against the  Company  regarding
    trademark,  trade name, patent, mask  work, copyright, license, trade secret
    or other infringement  which could  have a  material adverse  effect on  the
    financial  condition, business,  results of  operations or  prospects of the
    Company.
 
        (o) The Company has not been advised, and has no reason to believe, that
    it is not conducting business in compliance with all applicable laws,  rules
    and  regulations of  the jurisdictions in  which it  is conducting business,
    including, without  limitation,  all  applicable local,  state  and  federal
    environmental  laws  and  regulations,  except where  failure  to  be  so in
    compliance would not  materially adversely affect  the financial  condition,
    properties, business, results of operations or prospects of the Company.
 
        (p)  The  Company has  filed all  necessary  federal, state  and foreign
    income and  franchise tax  returns and  have  paid all  taxes shown  as  due
    thereon,  except for those returns or taxes as to which in the aggregate the
    failure to so file or  pay would not have a  material adverse effect on  the
    financial   condition,  properties,  business,   results  of  operations  or
    prospects of the Company; and
 
                                       5
<PAGE>
    the Company has no knowledge of any  tax deficiency which has been or  might
    be  asserted or  threatened against the  Company which  could materially and
    adversely affect the financial  condition, properties, business, results  of
    operations or prospects of the Company.
 
        (q) The Company is not an "investment company" within the meaning of the
    Investment Company Act of 1940, as amended.
 
        (r) The Company has not distributed and will not distribute prior to the
    First Closing Date any offering material in connection with the offering and
    sale  of  the  Common Shares  other  than the  Prospectus,  the Registration
    Statement and the other materials permitted by the Act.
 
        (s) The Company  maintains insurance  of the  types and  in the  amounts
    generally  deemed adequate for its business,  including, but not limited to,
    insurance covering real and personal property owned or leased by the Company
    against theft, damage, destruction,  acts of vandalism  and all other  risks
    customarily  insured against,  all of which  insurance is in  full force and
    effect.
 
        (t) The Company has not at any time during the last five years (i)  made
    any  unlawful contribution to any candidate for foreign office, or failed to
    disclose fully  any contribution  in  violation of  law,  or (ii)  made  any
    payment  to any federal or state  governmental officer or official, or other
    person charged  with  similar  public or  quasi-public  duties,  other  than
    payments  required or  permitted by  the laws  of the  United States  or any
    jurisdiction thereof.
 
        (u) The Company has not taken and will not take, directly or indirectly,
    any action designed  to or  that might be  reasonably expected  to cause  or
    result  in stabilization or manipulation of the price of the Common Stock to
    facilitate the sale or resale of the Common Shares.
 
        (v) The  Company  (i) is  in  compliance  with any  and  all  applicable
    foreign,  federal,  state and  local laws  and  regulations relating  to the
    protection of human health and safety, the environment or hazardous or toxic
    substances or  wastes, pollutants  or contaminants  ("Environmental  Laws"),
    (ii)  has received all permits, licenses or other approvals required of them
    under applicable Environmental Laws to conduct its business and (iii) is  in
    compliance  with all  terms and  conditions of  any such  permit, license or
    approval, except where such  noncompliance with Environmental Laws,  failure
    to  receive  required permits,  licenses or  other  approvals or  failure to
    comply with the terms and conditions of such permits, licenses or  approvals
    would not, singly or in the aggregate, have a material adverse effect on the
    Company.
 
        (w)  The  Company reasonably  believes  that the  costs  and liabilities
    (including,  without  limitation,  any  capital  or  operating  expenditures
    required   for   clean-up,  closure   of   properties  or   compliance  with
    Environmental  Laws  or  any  permit,  license  or  approval,  any   related
    constraints  on operating activities and  any potential liabilities to third
    parties) associated with the effect  of Environmental Laws on the  business,
    operations and properties of the Company, will not, in the aggregate, have a
    material adverse effect on the Company.
 
        (x)  Except  as described  in the  Prospectus,  there are  no contracts,
    agreements or understandings  between the  Company and  any person  granting
    such  person  the  right  to  require the  Company  to  file  a registration
    statement under the  Securities Act with  respect to any  securities of  the
    Company or to require the Company to include such securities with the Shares
    registered pursuant to the Registration Statement.
 
        (y)  The Company  has complied with  all provisions  of Section 517.075,
    Florida Statutes relating to doing business  with the Government of Cuba  or
    with any person or affiliate located in Cuba.
 
    SECTION  3.    REPRESENTATIONS  AND WARRANTIES  OF  THE  UNDERWRITERS.   The
Representatives, on behalf of the several Underwriters, represent and warrant to
the Company  that  the information  set  forth (i)  on  the cover  page  of  the
Prospectus  with respect  to price,  underwriting discounts  and commissions and
terms of offering and (ii) under "Underwriting" in the Prospectus was  furnished
to  the Company by and on behalf of  the Underwriters for use in connection with
the preparation of the
 
                                       6
<PAGE>
Registration Statement  and  the  Prospectus  and is  correct  in  all  material
respects.  The  Representatives  represent  and  warrant  that  they  have  been
authorized by each  of the other  Underwriters as the  Representatives to  enter
into  this  Agreement on  its behalf  and to  act  for it  in the  manner herein
provided.
 
    SECTION 4.  PURCHASE, SALE AND DELIVERY  OF COMMON SHARES.  On the basis  of
the  representations, warranties and agreements herein contained, but subject to
the terms and conditions herein set forth, the Company agrees to issue and  sell
to  the  Underwriters all  of the  Firm Common  Shares. The  Underwriters agree,
severally and  not jointly,  to purchase  from the  Company the  number of  Firm
Common  Shares described below. The  purchase price per share  to be paid by the
several Underwriters to the Company shall be $    per share.
 
The obligation of each Underwriter to the Company shall be to purchase from  the
Company that number of shares set forth opposite the name of such Underwriter in
Schedule A hereto.
 
Delivery  of certificates  for the  Firm Common  Shares to  be purchased  by the
Underwriters and payment therefor  shall be made at  the offices of Fulbright  &
Jaworski  L.L.P., Houston, Texas (or  such other place as  may be agreed upon by
the Company and the Representatives) at such  time and date, not later than  the
third  (or,  if the  Firm  Common Shares  are  priced, as  contemplated  by Rule
15c6-1(c) under the Securities Exchange Act of 1934, after 4:30 P.M.  Washington
D.C.  time, the fourth) full  business day following the  first date that any of
the Common Shares  are released  by you  for sale to  the public,  as you  shall
designate  by at least 48 hours prior  notice to the Company (the "First Closing
Date"); provided, however, that if  the Prospectus is at  any time prior to  the
First  Closing Date  recirculated to  the public,  the First  Closing Date shall
occur upon the later of the third or  fourth, as the case may be, full  business
day  following the first date that any of  the Common Shares are released by you
for sale to the  public or the  date that is  48 hours after  the date that  the
Prospectus has been so recirculated.
 
Delivery  of certificates  for the  Firm Common  Shares shall  be made  by or on
behalf of the Company to you,  for the respective accounts of the  Underwriters,
against  payment by you,  for the accounts  of the several  Underwriters, of the
purchase price  therefor by  wire transfer,  certified or  official bank  checks
payable  in  clearing house  (next  day available)  funds  to the  order  of the
Company. The certificates for the Firm Common Shares shall be registered in such
names and denominations as you shall  have requested at least two full  business
days  prior to the First Closing Date,  and shall be made available for checking
and packaging on the business day preceding the First Closing Date at a location
in New York, New York as may be designated by you. Time shall be of the essence,
and delivery at  the time and  place specified  by this Agreement  is a  further
condition to the obligations of the Underwriters.
 
In  addition, on  the basis  of the  representations, warranties  and agreements
herein contained, but subject to the terms and conditions herein set forth,  the
Company  hereby  grants  an  option to  the  several  Underwriters  to purchase,
severally and not jointly, up to an aggregate of 420,000 Optional Common  Shares
at  the purchase price per share to be  paid for the Firm Common Shares, for use
solely in  covering any  over-allotments made  by  you for  the account  of  the
Underwriters  in the sale and distribution of the Firm Common Shares. The option
granted hereunder may be exercised at any  time (but not more than once)  within
30  days after the first date that any  of the Common Shares are released by you
for sale to  the public, upon  notice by you  to the Company  setting forth  the
aggregate  number of  Optional Common  Shares as  to which  the Underwriters are
exercising the option, the names and denominations in which the certificates for
such shares  are  to  be  registered  and the  time  and  place  at  which  such
certificates  will be delivered. Such time of delivery (which may not be earlier
than the First Closing  Date), being herein referred  to as the "Second  Closing
Date,"  shall be  determined by  you, but if  at any  time other  than the First
Closing Date shall not be earlier than  three nor later than five full  business
days  after delivery of such  notice of exercise. The  number of Optional Common
Shares to be purchased  by each Underwriter shall  be determined by  multiplying
the  number of Optional Common Shares to be sold by the Company pursuant to such
notice of exercise by a fraction, the  numerator of which is the number of  Firm
Common Shares to be purchased by such
 
                                       7
<PAGE>
Underwriter  as set forth opposite its name in Schedule A and the denominator of
which is  2,800,000 (subject  to such  adjustments to  eliminate any  fractional
share  purchases  as you  in  your discretion  may  make). Certificates  for the
Optional Common Shares will be made available for checking and packaging on  the
business  day preceding the Second  Closing Date at a  location in New York, New
York as may be designated by you. The manner of payment for and delivery of  the
Optional Common Shares shall be the same as for the Firm Common Shares purchased
from  the Company  as specified  in the  two preceding  paragraphs. At  any time
before lapse of the option, you may cancel such option by giving written  notice
of such cancellation to the Company.
 
You  have advised the Company that each Underwriter has authorized you to accept
delivery of its  Common Shares, to  make payment and  to receipt therefor.  You,
individually  and not as the Representatives of the Underwriters, may (but shall
not be obligated to) make payment for  any Common Shares to be purchased by  any
Underwriter whose funds shall not have been received by you by the First Closing
Date  or the Second  Closing Date, as the  case may be, for  the account of such
Underwriter, but any such payment shall not relieve such Underwriter from any of
its obligations under this Agreement.
 
Subject to the terms and conditions  hereof, the Underwriters propose to make  a
public  offering of their respective portions of the Common Shares as soon after
the effective  date of  the Registration  Statement as  in the  judgment of  the
Representatives  is advisable and at the public  offering price set forth on the
cover page of and on the terms set forth in the Prospectus.
 
    SECTION 5.   COVENANTS OF  THE COMPANY.   The Company  covenants and  agrees
that:
 
        (a)  The  Company will  use  its reasonable  best  efforts to  cause the
    Registration Statement and any  amendment thereof, if  not effective at  the
    time  and date that this Agreement is  executed and delivered by the parties
    hereto, to become  effective. If  the Registration Statement  has become  or
    becomes effective pursuant to Rule 430A of the Rules and Regulations, or the
    filing  of the  Prospectus is  otherwise required  under Rule  424(b) of the
    Rules and  Regulations,  the  Company will  file  the  Prospectus,  properly
    completed,  pursuant to the applicable paragraph of Rule 424(b) of the Rules
    and Regulations within the time period prescribed and will provide  evidence
    satisfactory  to you of such timely filing. The Company will promptly advise
    you in writing (i) of the receipt of any comments of the Commission, (ii) of
    any request  of  the  Commission  for amendment  of  or  supplement  to  the
    Registration  Statement (either before  or after it  becomes effective), any
    Preliminary Prospectus  or the  Prospectus  or for  additional  information,
    (iii)  when the Registration Statement shall have become effective, and (iv)
    of the  issuance  by  the  Commission  of  any  stop  order  suspending  the
    effectiveness  of the  Registration Statement or  of the  institution of any
    proceedings for that purpose.  If the Commission shall  enter any such  stop
    order  at any  time, the  Company will  use its  reasonable best  efforts to
    obtain the  lifting of  such  order at  the  earliest possible  moment.  The
    Company  will  not  file any  amendment  or supplement  to  the Registration
    Statement (either before  or after  it becomes  effective), any  Preliminary
    Prospectus  or the Prospectus  of which you  have not been  furnished with a
    copy a  reasonable time  prior to  such filing  or to  which you  reasonably
    object  or which is not in compliance  in all material respects with the Act
    and the Rules and Regulations.
 
        (b) The Company will prepare and file with the Commission, promptly upon
    your request, any amendments or supplements to the Registration Statement or
    the Prospectus  which in  your judgment  may be  necessary or  advisable  to
    enable  the several Underwriters to continue  the distribution of the Common
    Shares and will use its reasonable best efforts to cause the same to  become
    effective  as promptly  as possible. The  Company will  fully and completely
    comply, in all material  respects, with the provisions  of Rule 430A of  the
    Rules   and  Regulations  with  respect  to  information  omitted  from  the
    Registration Statement in reliance upon such Rule.
 
        (c) During the period within which  a prospectus relating to the  Common
    Shares  is required by  law to be  delivered in connection  with sales by an
    Underwriter or  dealer,  if any  event  occurs, as  a  result of  which  the
    Prospectus,  including  any  amendments  or  supplements,  would  include an
 
                                       8
<PAGE>
    untrue statement of  a material  fact, or omit  to state  any material  fact
    required  to be stated therein or  necessary to make the statements therein,
    in  the  light  of  the  circumstances  under  which  they  were  made,  not
    misleading,  or, if  it is  necessary at any  time to  amend the Prospectus,
    including any amendments or supplements, to comply with the Act or the Rules
    and Regulations,  the Company  will  promptly advise  you thereof  and  will
    promptly  prepare  and file  with  the Commission,  at  its own  expense, an
    amendment or supplement which will correct such statement or omission or  an
    amendment  or supplement which will effect  such compliance and will use its
    reasonable best efforts  to cause the  same to become  effective as soon  as
    possible;  and, in case any Underwriter  is required to deliver a prospectus
    after such period,  the Company  upon request, but  at the  expense of  such
    Underwriter,  will  promptly prepare  such  amendment or  amendments  to the
    Registration Statement  and  such  Prospectus  or  Prospectuses  as  may  be
    necessary to permit compliance with the requirements of the Act or the Rules
    and Regulations.
 
        (d)  As soon as practicable, but not later than 45 days after the end of
    the first quarter ending after one year following the "effective date of the
    Registration Statement"  (as  defined  in  Rule  158(c)  of  the  Rules  and
    Regulations),  the  Company will  make generally  available to  its security
    holders an earnings statement (which need not be audited) covering a  period
    of  12  consecutive  months  beginning  after  the  effective  date  of  the
    Registration Statement  which  will  satisfy  the  provisions  of  the  last
    paragraph of Section 11(a) of the Act.
 
        (e)  During the period within which  a prospectus relating to the Common
    Stock is required  by law to  be delivered  in connection with  sales by  an
    Underwriter  or dealer, the Company, at its  expense, will furnish to you or
    mail to your order copies of the Registration Statement, the Prospectus, the
    Preliminary Prospectus  and  all  amendments and  supplements  to  any  such
    documents  in each case as  soon as available and  in such quantities as you
    may request, for the purposes contemplated by the Act.
 
        (f) The Company shall cooperate with you and your counsel as  reasonably
    required  in order to qualify  or register the Common  Shares for sale under
    (or obtain exemptions  from the application  of) the Blue  Sky laws of  such
    jurisdictions as you designate, will comply with such laws and will continue
    such  qualifications,  registrations and  exemptions  in effect  so  long as
    reasonably required for the distribution  of the Common Shares. The  Company
    shall  not be  required to  qualify as  a foreign  corporation or  to file a
    general consent to service of process  in any such jurisdiction where it  is
    not  presently  qualified or  where it  would  be subject  to taxation  as a
    foreign corporation. The Company will advise you promptly of the  suspension
    of  the qualification or registration of (or any such exemption relating to)
    the Common Shares for offering, sale  or trading in any jurisdiction or  any
    initiation  or threat  of any  proceeding for any  such purpose,  and in the
    event  of  the  issuance  of   any  order  suspending  such   qualification,
    registration  or exemption, the Company, with your cooperation, will use its
    reasonable best efforts to obtain the withdrawal thereof.
 
        (g) During the period of five years hereafter, the Company will  furnish
    to  the Representatives and, upon request of the Representatives, to each of
    the other Underwriters:  (i) as soon  as practicable after  the end of  each
    fiscal  year, copies  of the  Annual Report  to Stockholders  of the Company
    containing the balance sheet of the Company  as of the close of such  fiscal
    year  and statements of income, stockholders'  equity and cash flows for the
    year  then  ended  and  the  auditor's  report  thereon  of  the   Company's
    independent public accountants; (ii) as soon as practicable after the filing
    thereof,  copies  of  each  proxy statement,  Annual  Report  on  Form 10-K,
    Quarterly Report on  Form 10-Q, Report  on Form  8-K; and (iii)  as soon  as
    available,  copies  of any  report or  communication  of the  Company mailed
    generally to holders of its Common Stock.
 
        (h) During the period of 180 days  after the first date that any of  the
    Common  Shares are released by you for sale to the public, without the prior
    written consent of Montgomery Securities  (which consent may be withheld  at
    the  sole discretion  of the  Montgomery Securities),  the Company  will not
    issue, offer, sell, grant options to purchase or otherwise dispose of any of
    the
 
                                       9
<PAGE>
    Company's equity  securities or  any other  securities convertible  into  or
    exchangeable  with its Common Stock or other equity security, except for (i)
    the issuance of the  Common Shares pursuant  to the Registration  Statement,
    (ii)  the grant  of options under  the 1992  Plan and (iii)  the issuance of
    shares of  Common Stock  pursuant to  the exercise  of options  or  warrants
    outstanding  on the date  of this Agreement and  options granted pursuant to
    clause (ii) of this Section 5(h).
 
        (i) The Company will apply  the net proceeds of  the sale of the  Common
    Shares  sold by it substantially in accordance with its statements under the
    caption "Use of Proceeds" in the Prospectus.
 
        (j)  The  Company will  use its reasonable  best efforts  to qualify  or
    register  its Common  Stock for  sale in  non-issuer transactions  under (or
    obtain exemptions from the application of) the Blue Sky laws of the State of
    California (and  thereby permit  market  making transactions  and  secondary
    trading  in the Company's Common Stock in California), will comply with such
    Blue Sky  laws  and will  continue  such qualifications,  registrations  and
    exemptions in effect for a period of five years after the date hereof.
 
    You,  on behalf of the Underwriters, may,  in your sole discretion, waive in
writing the performance  by the  Company of  any one  or more  of the  foregoing
covenants or extend the time for their performance.
 
    SECTION  6.    PAYMENT  OF  EXPENSES.    Whether  or  not  the  transactions
contemplated hereunder are consummated or this Agreement becomes effective or is
terminated, the Company agrees to pay  all costs, fees and expenses incurred  in
connection  with the performance of its  obligations hereunder and in connection
with the  transactions  contemplated  hereby,  including  without  limiting  the
generality  of  the foregoing,  (i) all  expenses incident  to the  issuance and
delivery of the Common Shares (including all printing and engraving costs), (ii)
all fees and expenses of the registrar  and transfer agent of the Common  Stock,
(iii) all necessary issue, transfer and other stamp taxes in connection with the
issuance  and sale of the  Common Shares to the  Underwriters, (iv) all fees and
expenses  of  the  Company's  counsel  and  the  Company's  independent   public
accountants,  (v)  all  costs  and  expenses  incurred  in  connection  with the
preparation, printing,  filing, shipping  and distribution  of the  Registration
Statement,  each  Preliminary  Prospectus  and  the  Prospectus  (including  all
exhibits and financial statements) and  all amendments and supplements  provided
for  herein,  this Agreement,  the  Agreement Among  Underwriters,  the Selected
Dealers Agreement, the Underwriters'  Questionnaire, the Underwriters' Power  of
Attorney  and  the  Blue  Sky  memorandum,  (vi)  all  filing  fees,  reasonable
attorneys' fees and  expenses incurred  by the  Company or  the Underwriters  in
connection  with  qualifying or  registering (or  obtaining exemptions  from the
qualification or registration of) all or any part of the Common Shares for offer
and sale  under  the  Blue Sky  laws,  (vii)  the filing  fee  of  the  National
Association  of Securities Dealers,  Inc., and (viii) all  other fees, costs and
expenses referred  to  in Item  13  of  the Registration  Statement.  Except  as
provided  in this Section 6,  Section 8 and Section  10 hereof, the Underwriters
shall pay all  of their own  expenses, including the  fees and disbursements  of
their  counsel  (excluding  those  relating  to  qualification,  registration or
exemption under  the Blue  Sky laws  and  the Blue  Sky memorandum  referred  to
above).
 
                                       10
<PAGE>
    SECTION  7.    CONDITIONS  OF  THE OBLIGATIONS  OF  THE  UNDERWRITERS.   The
obligations of the several Underwriters to purchase and pay for the Firm  Common
Shares  on the First Closing  Date and the Optional  Common Shares on the Second
Closing Date  shall  be subject  to  the  accuracy of  the  representations  and
warranties on the part of the Company herein set forth as of the date hereof and
as  of the First Closing Date or the Second Closing Date, as the case may be, to
the accuracy  of  the  statements  of Company  officers  made  pursuant  to  the
provisions  hereof,  to  the  performance  by  the  Company  of  its obligations
hereunder, and to the following additional conditions:
 
        (a) The Registration  Statement shall  have become  effective not  later
    than  5:00 P.M. (or, in the case  of a registration statement filed pursuant
    to Rule 462(b) of the Rules  and Regulations relating to the Common  Shares,
    not  later than  10:00 P.M.),  Washington, D.C.  Time, on  the date  of this
    Agreement, or at such later time as shall have been consented to by you;  if
    the  filing  of  the  Prospectus, or  any  supplement  thereto,  is required
    pursuant to Rule 424(b) of the  Rules and Regulations, the Prospectus  shall
    have  been filed in the  manner and within the  time period required by Rule
    424(b) of the  Rules and Regulations;  prior to such  Closing Date, no  stop
    order  suspending the effectiveness of the Registration Statement shall have
    been issued and no proceedings for  that purpose shall have been  instituted
    or  shall be pending  or, to the knowledge  of the Company  or you, shall be
    contemplated by  the  Commission; and  any  request of  the  Commission  for
    inclusion  of  additional  information  in  the  Registration  Statement, or
    otherwise, shall have been complied with to your satisfaction.
 
        (b) You shall be satisfied that  since the respective dates as of  which
    information is given in the Registration Statement and Prospectus, (i) there
    shall  not have been any  change in the capital  stock of the Company (other
    than upon  the  sale of  the  Common  Shares hereunder,  the  conversion  of
    convertible  securities into  shares of Common  Stock, the  grant of options
    under the 1992 Plan and upon the  exercise of options and warrants, each  as
    described  in  the Registration  Statement) or  any  material change  in the
    indebtedness (other than in the ordinary course of business) of the Company,
    (ii) except as set  forth or contemplated by  the Registration Statement  or
    the  Prospectus, no material oral or  written agreement or other transaction
    shall have been entered into  by the Company, which  is not in the  ordinary
    course  of business and which could reasonably be anticipated to result in a
    material reduction in the future earnings  of the Company, (iii) no loss  or
    damage  (whether or not insured)  to the property of  the Company shall have
    been  sustained  which  materially  and  adversely  affects  the   financial
    condition,  properties, business, results of  operations or prospects of the
    Company, (iv) no legal or governmental action, suit or proceeding  affecting
    the  Company which is material to the Company or which affects or may affect
    the transactions contemplated by this  Agreement shall have been  instituted
    or  threatened, and (v) there shall not have been any material change in the
    financial condition, properties, business, management, results of operations
    or prospects of the Company which makes it impractical or inadvisable in the
    judgment of  the Representatives  to  proceed with  the public  offering  or
    purchase the Common Shares as contemplated hereby.
 
        (c)  There shall have  been furnished to you,  as Representatives of the
    Underwriters, on each Closing  Date, in form  and substance satisfactory  to
    you, except as otherwise expressly provided below:
 
           (i)  An  opinion  of Fulbright  &  Jaworski L.L.P.,  counsel  for the
       Company, addressed to the Underwriters and dated the First Closing  Date,
       or the Second Closing Date, as the case may be, substantially in the form
       attached hereto as Exhibit A.
 
    In rendering such opinion, such counsel may rely as to matters of local law,
    on  opinions of local counsel, and as to matters of fact, on certificates of
    officers of the Company and of  governmental officials, in which case  their
    opinion  is to state  that they are  so doing and  that the Underwriters are
    justified in relying  on such opinions  or certificates and  copies of  said
    opinions  or certificates  are to be  attached to the  opinion. Such counsel
    shall also include a statement to the  effect that nothing has come to  such
    counsel's  attention that  would lead  such counsel  to believe  that either
 
                                       11
<PAGE>
    at the effective  date of the  Registration Statement or  at the  applicable
    Closing  Date  the Registration  Statement or  the  Prospectus, or  any such
    amendment or supplement, contains any untrue statement of a material fact or
    omits to state a material fact required to be stated therein or necessary to
    make the statements therein, in the  light of the circumstances under  which
    they were made, not misleading;
 
           (ii)  Such opinion  or opinions  of Hyman,  Phelps &  McNamara, P.C.,
       special regulatory counsel for the Company, dated the First Closing  Date
       or the Second Closing Date, as the case may be, to the effect that:
 
               (1)  The  information  in  the Prospectus  under  the  first four
           paragraphs of  "Risk  Factor  --  Access to,  Approval  and  Sale  of
           Therapeutic  Products", "Risk Factors -- Governmental Regulation" and
           the first paragraph  of "Business --  Government Regulation," to  the
           extent that it constitutes matters of law, summaries of legal matters
           or  legal  conclusions,  has been  reviewed  by such  counsel  and is
           correct in all material respects.
 
    Such counsel shall also include a statement to the effect that, with respect
    to the description  of the  regulatory situation  of the  Company and  other
    statements  in the  above-referenced sections in  the Registration Statement
    and Prospectus, nothing has come to such counsel's attention that would lead
    such counsel  to  believe  that either  at  the  Effective Date  or  at  the
    applicable Closing Date the Registration Statement or the Prospectus, or any
    amendment or supplement thereto, contains any untrue statement of a material
    fact  or omits  to state a  material fact  required to be  stated therein or
    necessary to make the statements therein, in the light of the  circumstances
    under which they were made, not misleading.
 
          (iii)  Such opinion or  opinions of Cooley  Godward Castro Huddleson &
       Tatum, counsel for the Underwriters dated  the First Closing Date or  the
       Second   Closing  Date,  as  the  case   may  be,  with  respect  to  the
       incorporation of  the Company,  the validity  of the  Common Shares,  the
       Registration  Statement and the  Prospectus and other  related matters as
       you may reasonably require, and the Company shall have furnished to  such
       counsel  such documents and shall have  exhibited to them such papers and
       records as they may reasonably request  for the purpose of enabling  them
       to pass upon such matters. In connection with such opinions, such counsel
       may  rely on representations  or certificates of  officers of the Company
       and governmental officials.
 
          (iv) A certificate  of the  Company executed  by the  Chairman of  the
       Board  or President and the chief  financial or accounting officer of the
       Company, dated the First Closing Date or the Second Closing Date, as  the
       case may be, to the effect that:
 
               (1)  The representations and warranties  of the Company set forth
           in Section 2 of this Agreement are true and correct as of the date of
           this Agreement and as of the First Closing Date or the Second Closing
           Date, as the case may be, and  the Company has complied with all  the
           agreements  and  satisfied  all  the conditions  on  its  part  to be
           performed or satisfied on or prior to such Closing Date;
 
               (2) The  Commission  has  not  issued  any  order  preventing  or
           suspending  the use of  the Prospectus or  any Preliminary Prospectus
           filed as  a  part of  the  Registration Statement  or  any  amendment
           thereto;   no  stop   order  suspending  the   effectiveness  of  the
           Registration Statement has been issued;  and to the knowledge of  the
           respective  signers,  no  proceedings  for  that  purpose  have  been
           instituted or are pending or contemplated under the Act;
 
               (3) Each  of  the  respective  signers  of  the  certificate  has
           carefully  examined the Registration Statement and the Prospectus; to
           his knowledge, neither the Registration Statement nor the  Prospectus
           nor    any   amendment    or   supplement    thereto   includes   any
 
                                       12
<PAGE>
           untrue statement of a  material fact or omits  to state any  material
           fact  required  to  be  stated  therein  or  necessary  to  make  the
           statements therein, in  the light  of the  circumstances under  which
           they were made, not misleading;
 
               (4)  To each of the signer's knowledge, since the initial date on
           which the Registration Statement was filed, no agreement, written  or
           oral,  transaction or event  has occurred which  should have been set
           forth  in  an  amendment  to  the  Registration  Statement  or  in  a
           supplement  to  or amendment  of any  prospectus  which has  not been
           disclosed in such a supplement or amendment;
 
               (5) Since the respective dates  as of which information is  given
           in  the  Registration Statement  and  the Prospectus,  and  except as
           disclosed in or contemplated  by the Prospectus,  there has not  been
           any  material adverse  change or  a development  involving a material
           adverse change in the  condition (financial or otherwise),  business,
           properties,  results of  operations, management  or prospects  of the
           Company; and no legal or  governmental action, suit or proceeding  is
           pending  or threatened against  the Company which  is material to the
           Company, whether or  not arising  from transactions  in the  ordinary
           course  of business, or  which may adversely  affect the transactions
           contemplated by this  Agreement; since  such dates and  except as  so
           disclosed,  the Company  has not entered  into any  verbal or written
           agreement or other transaction which is not in the ordinary course of
           business or which could result in a material reduction in the  future
           earnings  of  the  Company  or  incurred  any  material  liability or
           obligation, direct, contingent  or indirect, made  any change in  its
           capital  stock, made  any material change  in its  short-term debt or
           funded debt or repurchased or otherwise acquired any of the Company's
           capital stock; and the Company has not declared or paid any dividend,
           or made any  other distribution, upon  its outstanding capital  stock
           payable  to  stockholders of  record  on a  date  prior to  the First
           Closing Date or Second Closing Date; and
 
               (6) Since the respective dates  as of which information is  given
           in  the  Registration  Statement  and the  Prospectus  and  except as
           disclosed in or contemplated by  the Prospectus, the Company has  not
           sustained   a  material  loss  or  damage  by  strike,  fire,  flood,
           windstorm, accident or other calamity (whether or not insured).
 
           (v) On the  date this  Agreement is executed  and also  on the  First
       Closing  Date and the Second  Closing Date a letter  addressed to you, as
       Representatives  of  the  Underwriters,  from  Arthur  Andersen   L.L.P.,
       independent  accountants, the first one  to be dated the  day the date of
       this Agreement, the second one to be dated the First Closing Date and the
       third one (in  the event  of a  Second Closing)  to be  dated the  Second
       Closing Date, in form and substance satisfactory to you.
 
          (vi)  On or before the First Closing Date, letters from each holder of
          percent or more of  the Company's Common Stock  and each director  and
       officer  of  the  Company, in  form  and substance  satisfactory  to you,
       confirming that for a period of 180 days after the first date that any of
       the Common Shares are released by you for sale to the public, such person
       will not  directly or  indirectly  sell or  offer  to sell  or  otherwise
       dispose of any shares of Common Stock or any right to acquire such shares
       without the prior written consent of Montgomery Securities, which consent
       may be withheld at the sole discretion of Montgomery Securities.
 
       All  such  opinions,  certificates,  letters and  documents  shall  be in
       compliance with the provisions  hereof only if  they are satisfactory  to
       you  and  to Cooley  Godward Castro  Huddleson &  Tatum, counsel  for the
       Underwriters. The Company shall furnish you with such manually signed  or
       conformed copies of such opinions, certificates, letters and documents as
       you  request. Any  certificate signed by  any officer of  the Company and
       delivered to the Representatives or to counsel for the Underwriters shall
       be deemed  to be  a representation  and warranty  by the  Company to  the
       Underwriters as to the statements made therein.
 
                                       13
<PAGE>
       If  any  condition  to  the  Underwriters'  obligations  hereunder  to be
       satisfied prior to or at the First Closing Date is not so satisfied, this
       Agreement at  your  election  will terminate  upon  notification  to  the
       Company  by you as  Representatives without liability on  the part of any
       Underwriter or  the  Company  except  for the  expenses  to  be  paid  or
       reimbursed  by the Company pursuant to Sections 6 and 8 hereof and except
       to the extent provided in Section 10 hereof.
 
    SECTION 8.   REIMBURSEMENT OF UNDERWRITERS'  EXPENSES.  Notwithstanding  any
other  provisions hereof, if this Agreement  shall be terminated by you pursuant
to Section 7, or  if the sale to  the Underwriters of the  Common Shares at  the
First Closing is not consummated because of any refusal, inability or failure on
the  part of the Company  to perform any agreement herein  or to comply with any
provision hereof, the Company agrees to reimburse you and the other Underwriters
upon demand  for all  out-of-pocket  expenses that  shall have  been  reasonably
incurred  by you and them in connection  with the proposed purchase and the sale
of the Common  Shares, including but  not limited to  fees and disbursements  of
counsel,  printing  expenses, travel  expenses,  postage, messenger  charges and
telephone  charges  relating  directly  to  the  offering  contemplated  by  the
Prospectus.  Any such termination shall be without liability of any party to any
other party except that the provisions of this Section 8, Section 6 and  Section
10 shall at all times be effective and shall apply.
 
    SECTION  9.  EFFECTIVENESS  OF REGISTRATION STATEMENT.   You and the Company
will use  your  and  its  reasonable best  efforts  to  cause  the  Registration
Statement  to  become  effective, to  prevent  the  issuance of  any  stop order
suspending the effectiveness  of the  Registration Statement and,  if such  stop
order be issued, to obtain as soon as possible the lifting thereof.
 
    SECTION 10.  INDEMNIFICATION.
 
        (a)  The Company agrees to indemnify  and hold harmless each Underwriter
    and each person, if any, who controls any Underwriter within the meaning  of
    the  Act against any losses, claims, damages, liabilities or expenses, joint
    or several, to which such Underwriter or such controlling person may  become
    subject, under the Act, the Securities Exchange Act of 1934, as amended (the
    "Exchange  Act"), or other federal or  state statutory law or regulation, or
    at common law or  otherwise (including in settlement  of any litigation,  if
    such  settlement  is  effected with  the  written consent  of  the Company),
    insofar as such losses, claims, damages, liabilities or expenses (or actions
    in respect thereof as contemplated below) arise out of or are based upon any
    untrue statement or alleged untrue statement of any material fact  contained
    in  the Registration Statement, any  Preliminary Prospectus, the Prospectus,
    or any amendment or supplement  thereto, or arise out  of or are based  upon
    the  omission or alleged  omission to state  in any of  them a material fact
    required to be stated therein or necessary to make the statements in any  of
    them,  in the  light of  the circumstances under  which they  were made, not
    misleading, or  arise out  of  or are  based  in whole  or  in part  on  any
    inaccuracy  in the representations  and warranties of  the Company contained
    herein or any failure of the Company to perform its obligations hereunder or
    under law; and  will reimburse  each Underwriter and  each such  controlling
    person  for any  legal and  other expenses  as such  expenses are reasonably
    incurred by such Underwriter or  such controlling person in connection  with
    investigating,  defending, settling,  compromising or paying  any such loss,
    claim, damage, liability,  expense or  action; provided,  however, that  the
    Company  will not  be liable in  any such case  to the extent  that any such
    loss, claim, damage, liability or expense arises out of or is based upon  an
    untrue statement or alleged untrue statement or omission or alleged omission
    made   in  the  Registration  Statement,  any  Preliminary  Prospectus,  the
    Prospectus or any amendment  or supplement thereto in  reliance upon and  in
    conformity with the information furnished to the Company pursuant to Section
    3 hereof; and, provided further, that the Company shall not be liable in any
    such  case with respect to any Preliminary Prospectus to the extent that any
    such loss, claim, damage or liability  of such Underwriter results from  the
    fact  the such Underwriter sold Common Shares  to a person to whom there was
    not sent or given  at or prior  to the written confirmation  of such sale  a
    copy  of the Prospectus in  any case where such  delivery is required by the
    Act, if  the  Company  has  previously  furnished  copies  thereof  to  such
    Underwriter
 
                                       14
<PAGE>
    and  the  loss,  claim, damage,  liability  or expense  of  such Underwriter
    results from an untrue statement or omission of a material fact contained in
    the Preliminary  Prospectus  which  was  corrected  in  the  Prospectus.  In
    addition  to its  other obligations  under this  Section 10(a),  the Company
    agrees that, as an interim measure during the pendency of any claim, action,
    investigation, inquiry or other proceeding arising out of or based upon  any
    statement  or  omission,  or  any  alleged  statement  or  omission,  or any
    inaccuracy in the representations  and warranties of  the Company herein  or
    failure  to  perform its  obligations hereunder,  all  as described  in this
    Section 10(a), it will reimburse each  Underwriter on a quarterly basis  for
    all   reasonable  legal  or  other  expenses  incurred  in  connection  with
    investigating or defending any such claim, action, investigation, inquiry or
    other proceeding, notwithstanding the absence of a judicial determination as
    to the propriety and enforceability of the Company's obligation to reimburse
    each Underwriter for such  expenses and the  possibility that such  payments
    might  later  be  held  to  have  been  improper  by  a  court  of competent
    jurisdiction. To the extent that  any such interim reimbursement payment  is
    so  held to have been improper, each Underwriter shall promptly return it to
    the Company  together with  interest, compounded  daily, determined  on  the
    basis  of the prime rate (or other  commercial lending rate for borrowers of
    the highest credit standing) announced from time to time by Bank of  America
    NT&SA,  San  Francisco,  California  (the "Prime  Rate").  Any  such interim
    reimbursement payments which are not made  to an Underwriter within 30  days
    of  a request for reimbursement, shall bear  interest at the Prime Rate from
    the date of such  request. This indemnity agreement  will be in addition  to
    any liability which the Company may otherwise have.
 
        (b)  Each  Underwriter will  severally indemnify  and hold  harmless the
    Company, each  of  its  directors,  each of  its  officers  who  signed  the
    Registration  Statement and  each person, if  any, who  controls the Company
    within the  meaning  of  the  Act,  against  any  losses,  claims,  damages,
    liabilities  or expenses to which the Company, or any such director, officer
    or controlling person may become subject,  under the Act, the Exchange  Act,
    or  other federal or state statutory law  or regulation, or at common law or
    otherwise (including in settlement of any litigation, if such settlement  is
    effected  with the  written consent  of such  Underwriter), insofar  as such
    losses, claims,  damages, liabilities  or expenses  (or actions  in  respect
    thereof  as contemplated below) arise out of or are based upon any untrue or
    alleged untrue statement of any material fact contained in the  Registration
    Statement,  any Preliminary Prospectus, the  Prospectus, or any amendment or
    supplement thereto,  or arise  out of  or  are based  upon the  omission  or
    alleged  omission to  state therein  a material  fact required  to be stated
    therein or necessary  to make the  statements therein, in  the light of  the
    circumstances  under which they  were made, not misleading,  in each case to
    the extent, but only  to the extent, that  such untrue statement or  alleged
    untrue   statement  or  omission  or  alleged   omission  was  made  in  the
    Registration Statement, any Preliminary  Prospectus, the Prospectus, or  any
    amendment or supplement thereto, in reliance upon and in conformity with the
    information  furnished to the Company pursuant to Section 3 hereof; and will
    reimburse the Company, or any  such director, officer or controlling  person
    for  any legal and other expense reasonably  incurred by the Company, or any
    such  director,   officer  or   controlling   person  in   connection   with
    investigating,  defending, settling,  compromising or paying  any such loss,
    claim, damage,  liability,  expense or  action.  In addition  to  its  other
    obligations  under  this Section  10(b),  each Underwriter  severally agrees
    that, as  an interim  measure  during the  pendency  of any  claim,  action,
    investigation,  inquiry or other proceeding arising out of or based upon any
    statement or omission, or  any alleged statement  or omission, described  in
    this  Section 10(b)  which relates to  information furnished  to the Company
    pursuant to Section  3 hereof, it  will reimburse the  Company (and, to  the
    extent applicable, each officer, director, controlling person on a quarterly
    basis for all reasonable legal or other expenses incurred in connection with
    investigating or defending any such claim, action, investigation, inquiry or
    other proceeding, notwithstanding the absence of a judicial determination as
    to  the  propriety and  enforceability  of the  Underwriters'  obligation to
    reimburse  the  Company  (and,  to  the  extent  applicable,  each  officer,
    director,  controlling person)  for such  expenses and  the possibility that
    such payments might later be held to have been
 
                                       15
<PAGE>
    improper by a court of competent  jurisdiction. To the extent that any  such
    interim  reimbursement payment is so held to have been improper, the Company
    (and, to the extent applicable,  each officer, director, controlling  person
    shall  promptly  return  it  to  the  Underwriters  together  with interest,
    compounded daily,  determined on  the  basis of  the  Prime Rate.  Any  such
    interim  reimbursement payments which are not  made to the Company within 30
    days of a request for reimbursement,  shall bear interest at the Prime  Rate
    from  the date of such request. This indemnity agreement will be in addition
    to any liability which such Underwriter may otherwise have.
 
        (c) Promptly after receipt by an indemnified party under this Section 10
    of notice of the commencement of any action, such indemnified party will, if
    a claim in respect thereof is to be made against an indemnifying party under
    this  Section  10,  notify  the   indemnifying  party  in  writing  of   the
    commencement  thereof; but the omission so  to notify the indemnifying party
    will not relieve it from any liability which it may have to any  indemnified
    party  for  contribution or  otherwise  than under  the  indemnity agreement
    contained in this  Section 10 or  to the extent  it is not  prejudiced as  a
    proximate result of such failure. In case any such action is brought against
    any  indemnified party and  such indemnified party seeks  or intends to seek
    indemnity from  an  indemnifying  party,  the  indemnifying  party  will  be
    entitled  to participate in,  and, to the  extent that it  may wish, jointly
    with all  other  indemnifying  parties similarly  notified,  to  assume  the
    defense  thereof with  counsel reasonably  satisfactory to  such indemnified
    party; provided, however, if the defendants in any such action include  both
    the  indemnified party and the indemnifying  party and the indemnified party
    shall have reasonably  concluded that there  may be a  conflict between  the
    positions  of the indemnifying party and the indemnified party in conducting
    the defense of any such action or that there may be legal defenses available
    to  it  and/or  other  indemnified  parties  which  are  different  from  or
    additional  to those  available to  the indemnifying  party, the indemnified
    party or parties shall have the  right to select separate counsel to  assume
    such  legal defenses  and to  otherwise participate  in the  defense of such
    action on  behalf of  such indemnified  party or  parties. Upon  receipt  of
    notice from the indemnifying party to such indemnified party of its election
    so  to assume  the defense  of such action  and approval  by the indemnified
    party of  counsel,  the  indemnifying  party will  not  be  liable  to  such
    indemnified  party under  this Section  10 for  any legal  or other expenses
    subsequently incurred  by  such indemnified  party  in connection  with  the
    defense  thereof unless (i)  the indemnified party  shall have employed such
    counsel in connection with  the assumption of  legal defenses in  accordance
    with  the  proviso  to  the  immediately  preceding  sentence  or  (ii)  the
    indemnifying party shall not  have employed counsel reasonably  satisfactory
    to  the  indemnified  party  to represent  the  indemnified  party  within a
    reasonable time after notice of commencement of the action, in each of which
    cases the  fees and  expenses of  counsel shall  be at  the expense  of  the
    indemnifying party.
 
        (d)  If the indemnification provided for  in this Section 10 is required
    by its terms but is  for any reason held to  be unavailable to or  otherwise
    insufficient to hold harmless an indemnified party under paragraphs (a), (b)
    or  (c) in respect  of any losses, claims,  damages, liabilities or expenses
    referred to herein, then each applicable indemnifying party shall contribute
    to the amount paid or payable by  such indemnified party as a result of  any
    losses,  claims, damages, liabilities or expenses  referred to herein (i) in
    such proportion as is appropriate to reflect the relative benefits  received
    by  the Company and the Underwriters from  the offering of the Common Shares
    or (ii) if the allocation provided by  clause (i) above is not permitted  by
    applicable law, in such proportion as is appropriate to reflect not only the
    relative  benefits referred  to in  clause (i)  above but  also the relative
    fault of the Company and the Underwriters in connection with the  statements
    or  omissions or inaccuracies  in the representations  and warranties herein
    which resulted in such losses, claims, damages, liabilities or expenses,  as
    well as any other relevant equitable considerations. The respective relative
    benefits  received by the Company and the Underwriters shall be deemed to be
    in the same proportion, in the case  of the Company as the total price  paid
    to  the Company for the Common Shares sold by it to the Underwriters (net of
    underwriting commissions but before deducting  expenses) bears to the  total
    price to the public set
 
                                       16
<PAGE>
    forth on the cover of the Prospectus, and in the case of the Underwriters as
    the  underwriting commissions received  by them bears to  the total price to
    the public set forth on the cover  of the Prospectus. The relative fault  of
    the  Company and the Underwriters shall be determined by reference to, among
    other things, whether the untrue or  alleged untrue statement of a  material
    fact  or the omission  or alleged omission  to state a  material fact or the
    inaccurate or the alleged inaccurate representation and/or warranty  relates
    to  information supplied by the Company or the Underwriters and the parties'
    relative intent, knowledge, access to information and opportunity to correct
    or prevent such statement or omission. The amount paid or payable by a party
    as a  result  of  the  losses, claims,  damages,  liabilities  and  expenses
    referred to above shall be deemed to include, subject to the limitations set
    forth  in subparagraph (c)  of this Section  10, any legal  or other fees or
    expenses reasonably incurred by such party in connection with  investigating
    or  defending any action or claim.  The provisions set forth in subparagraph
    (c) of this Section 10 with respect to notice of commencement of any  action
    shall  apply  if  a  claim  for  contribution  is  to  be  made  under  this
    subparagraph (d);  provided, however,  that no  additional notice  shall  be
    required  with respect to any  action for which notice  has been given under
    subparagraph (c)  for  purposes  of indemnification.  The  Company  and  the
    Underwriters  agree that it would not  be just and equitable if contribution
    pursuant to this Section  10 were determined solely  by pro rata  allocation
    (even if the Underwriters were treated as one entity for such purpose) or by
    any  other method of allocation which does not take account of the equitable
    considerations  referred  to   in  the   immediately  preceding   paragraph.
    Notwithstanding  the provisions of this Section  10, no Underwriter shall be
    required to  contribute any  amount in  excess of  the amount  of the  total
    underwriting commissions received by such Underwriter in connection with the
    Common  Shares underwritten by  it and distributed to  the public. No person
    guilty of fraudulent misrepresentation (within the meaning of Section  11(f)
    of  the Act) shall be  entitled to contribution from  any person who was not
    guilty of such fraudulent  misrepresentation. The Underwriters'  obligations
    to contribute pursuant to this Section 10 are several in proportion to their
    respective underwriting commitments and not joint.
 
        (e)  It is agreed that  any controversy arising out  of the operation of
    the interim reimbursement arrangements set forth in Sections 10(a) and 10(b)
    hereof, including the  amounts of any  requested reimbursement payments  and
    the  method of  determining such  amounts, shall  be settled  by arbitration
    conducted under the provisions of the Constitution and Rules of the Board of
    Governors of the New York  Stock Exchange, Inc. or  pursuant to the Code  of
    Arbitration Procedure of the NASD. Any such arbitration must be commenced by
    service  of a written demand for  arbitration or written notice of intention
    to arbitrate, therein electing  the arbitration tribunal.  In the event  the
    party demanding arbitration does not make such designation of an arbitration
    tribunal  in such demand or notice, then the party responding to said demand
    or notice is authorized to  do so. Such an  arbitration would be limited  to
    the  operation of the interim reimbursement provisions contained in Sections
    10(a) and  10(b) hereof  and would  not resolve  the ultimate  propriety  or
    enforceability  of the obligation to reimburse  expenses which is created by
    the provisions of such Sections 10(a) and 10(b) hereof.
 
    SECTION 11.   DEFAULT OF  UNDERWRITERS.   It shall  be a  condition to  this
Agreement  and the  obligation of  the Company  to sell  and deliver  the Common
Shares hereunder, and of each Underwriter  to purchase the Common Shares in  the
manner  as  described  herein, that,  except  as hereinafter  in  this paragraph
provided, each of  the Underwriters shall  purchase and pay  for all the  Common
Shares  agreed to be purchased by such  Underwriter hereunder upon tender to the
Representatives of all such shares in  accordance with the terms hereof. If  any
Underwriter  or  Underwriters default  in their  obligations to  purchase Common
Shares hereunder on either  the First or Second  Closing Date and the  aggregate
number of Common Shares which such defaulting Underwriter or Underwriters agreed
but  failed to purchase  on such Closing Date  does not exceed  10% of the total
number of Common Shares which the Underwriters are obligated to purchase on such
Closing Date, the non-defaulting Underwriters  shall be obligated severally,  in
proportion  to their  respective commitments  hereunder, to  purchase the Common
Shares which  such defaulting  Underwriters  agreed but  failed to  purchase  on
 
                                       17
<PAGE>
such  Closing  Date.  If any  Underwriter  or  Underwriters so  default  and the
aggregate number of Common Shares with  respect to which such default occurs  is
more   than  the   above  percentage   and  arrangements   satisfactory  to  the
Representatives and the Company for the purchase of such Common Shares by  other
persons  are not made  within 48 hours  after such default,  this Agreement will
terminate without liability on the part of any non-defaulting Underwriter or the
Company except for the expenses to be paid by the Company pursuant to Section  6
hereof and except to the extent provided in Section 10 hereof.
 
In  the event that Common Shares to which  a default relates are to be purchased
by  the  non-defaulting  Underwriters  or  by  another  party  or  parties,  the
Representatives  or the Company  shall have the  right to postpone  the First or
Second Closing Date, as the case may be, for not more than five business days in
order that the necessary changes  in the Registration Statement, Prospectus  and
any other documents, as well as any other arrangements, may be effected. As used
in this Agreement, the term "Underwriter" includes any person substituted for an
Underwriter  under this  Section 11.  Nothing herein  will relieve  a defaulting
Underwriter from liability for its default.
 
    SECTION 12.    EFFECTIVE  DATE.    This  Agreement  shall  become  effective
immediately  as to Sections 6, 8, 10, 13 and 14 and, as to all other provisions,
(i) if at the time of execution of this Agreement the Registration Statement has
not become effective, at 12:00 P.M., California time, on the first full business
day  following  the  effectiveness  of  the  Registration  Statement,  or   (ii)
immediately  as to  all of its  provisions if at  the time of  execution of this
Agreement the  Registration  Statement has  been  declared effective;  but  this
Agreement  shall nevertheless  become effective at  such earlier  time after the
Registration Statement becomes effective as you  may determine on and by  notice
to the Company or by release of any of the Common Shares for sale to the public.
For  the purposes of this Section 12, the  Common Shares shall be deemed to have
been so released upon the release for publication of any newspaper advertisement
relating to  the  Common Shares  or  upon written  notice  by you  (i)  advising
Underwriters  that the Common  Shares are released for  public offering, or (ii)
offering the Common Shares for sale  to securities dealers, whichever may  occur
first.
 
    SECTION  13.   TERMINATION.   Without limiting  the right  to terminate this
Agreement pursuant to any other provision hereof:
 
        (a) This Agreement may be terminated by the Company by notice to you  or
    by you by notice to the Company at any time prior to the time this Agreement
    shall  become effective as  to all its provisions,  and any such termination
    shall be without  liability on the  part of the  Company to any  Underwriter
    (except for any expenses to be paid or reimbursed by the Company pursuant to
    Sections  6 and  8 hereof and  except to  the extent provided  in Section 10
    hereof) or of any Underwriter to the Company (except to the extent  provided
    in Section 10 hereof).
 
        (b)  This Agreement  may also  be terminated by  you prior  to the First
    Closing  Date  by  notice  to   the  Company  (i)  if  additional   material
    governmental restrictions, not in force and effect on the date hereof, shall
    have been imposed upon trading in securities generally or minimum or maximum
    prices  shall have been generally established on the New York Stock Exchange
    or on the American Stock Exchange or  in the over the counter market by  the
    NASD, or trading in securities generally shall have been suspended on either
    such  exchange or in the  over the counter market by  the NASD, or a general
    banking moratorium  shall have  been  established by  federal, New  York  or
    California  authorities, (ii) if  an outbreak of  major hostilities or other
    national or international calamity or  any substantial change in  political,
    financial   or  economic  conditions  shall  have  occurred  or  shall  have
    accelerated or  escalated to  such an  extent, as,  in the  judgment of  the
    Representatives, to affect adversely the marketability of the Common Shares,
    (iii)  if any adverse event  shall have occurred or  shall exist which makes
    untrue or incorrect  in any  material respect any  statement or  information
    contained  in  the  Registration Statement  or  Prospectus or  which  is not
    reflected  in  the  Registration  Statement  or  Prospectus  but  should  be
    reflected  therein in order to make  the statements or information contained
    therein, in the light of the  circumstances under which they were made,  not
    misleading  in any material respect,  or (iv) if there  shall be any action,
 
                                       18
<PAGE>
    suit or  proceeding pending  or threatened,  or there  shall have  been  any
    development  or prospective development  involving particularly the business
    or properties or securities of the Company or the transactions  contemplated
    by this Agreement, which, in the reasonable judgment of the Representatives,
    may  materially and adversely affect the  Company's business or earnings and
    makes it impracticable or  inadvisable to offer or  sell the Common  Shares.
    Any  termination pursuant to this subsection  (b) shall without liability on
    the part of any Underwriter to the Company on the part of the Company to any
    Underwriter (except for any expenses to be paid or reimbursed by the Company
    pursuant to Sections 6  and 8 hereof  and except to  the extent provided  in
    Section 10 hereof.
 
    SECTION  14.   REPRESENTATIONS  AND INDEMNITIES  TO  SURVIVE DELIVERY.   The
respective  indemnities,  agreements,  representations,  warranties  and   other
statements  of the Company, of its officers  and of the several Underwriters set
forth in  or made  pursuant to  this Agreement  will remain  in full  force  and
effect,  regardless of any investigation made by or on behalf of any Underwriter
or the Company or  any of its  or their partners, officers  or directors or  any
controlling person, as the case may be, and will survive delivery of and payment
for the Common Shares sold hereunder and any termination of this Agreement.
 
    SECTION 15.  NOTICES.  All communications hereunder shall be in writing and,
if  sent to the Representatives shall  be mailed, delivered by overnight courier
or by facsimile transmission and confirmed to you at 600 Montgomery Street,  San
Francisco,  California 94111, Attention: Mike Dovey (Facsimile No. 415/249-5508,
Telephone No. 415/627-2000), with  a copy to Cooley  Godward Castro Huddleson  &
Tatum, 3000 Sand Hill Road, Bldg. 3, Suite 230, Menlo Park, CA 94025, Attention:
Mark  P. Tanoury, Esq. (Facsimile No. 415/854-2691, Telephone No. 415/843-5000);
and if sent to the  Company shall be mailed,  delivered by overnight courier  or
facsimile  transmission and  confirmed to the  Company at  800 Research Parkway,
Oklahoma City,  OK  73104,  Attention: President  (Facsimile  No.  415/290-4002,
Telephone  No. 405/290-4000)  with a copy  to Fulbright &  Jaworski L.L.P., 1301
McKinney Street,  Suite  5100,  Houston, TX  77010-3095,  Attention:  Robert  E.
Wilson,  Esq.  (Facsimile  No. 713/651-5246,  Telephone  No.  713/651-5151). The
Company or you may change the address for receipt of communications hereunder by
giving notice to the others.
 
    SECTION 16.  SUCCESSORS.  This Agreement will inure to the benefit of and be
binding upon the parties hereto, including any substitute Underwriters  pursuant
to  Section 11  hereof, and  to the  benefit of  the officers  and directors and
controlling persons referred to in Section 10, and in each case their respective
successors, personal representatives and assigns, and no other person will  have
any right or obligation hereunder. No such assignment shall relieve any party of
its obligations hereunder. The term "successors" shall not include any purchaser
of  the Common Shares as  such from any of the  Underwriters merely by reason of
such purchase.
 
    SECTION  17.     REPRESENTATION   OF  UNDERWRITERS.     You   will  act   as
Representatives  for the  several Underwriters  in connection  with all dealings
hereunder, and any action  under or in  respect of this  Agreement taken by  you
jointly  or by Montgomery  Securities, as Representatives,  will be binding upon
all the Underwriters.
 
    SECTION 18.  PARTIAL UNENFORCEABILITY.   The invalidity or  unenforceability
of  any Section, paragraph or  provision of this Agreement  shall not affect the
validity or enforceability of any other Section, paragraph or provision  hereof.
If  any Section,  paragraph or  provision of  this Agreement  is for  any reason
determined to be invalid or unenforceable, there shall be deemed to be made such
minor changes (and only such  minor changes) as are  necessary to make it  valid
and enforceable.
 
    SECTION  19.   APPLICABLE  LAW.   This  Agreement shall  be governed  by and
construed in accordance with the internal  laws (and not the laws pertaining  to
conflicts of laws) of the State of California.
 
              [The remainder of this page is intentionally blank]
 
                                       19
<PAGE>
    SECTION  20.  GENERAL.   This Agreement constitutes  the entire agreement of
the parties to this Agreement and supersedes  all prior written or oral and  all
contemporaneous oral agreements, understandings and negotiations with respect to
the   subject  matter  hereof.  This  Agreement   may  be  executed  in  several
counterparts, each one of  which shall be  an original, and  all of which  shall
constitute one and the same document.
 
In  this Agreement, the masculine, feminine  and neuter genders and the singular
and the plural include one another.  The section headings in this Agreement  are
for  the convenience of the parties only and will not affect the construction or
interpretation of this Agreement. This Agreement may be amended or modified, and
the observance of any term  of this Agreement may be  waived, only by a  writing
signed by the Company and you.
 
If  the foregoing  is in  accordance with  your understanding  of our agreement,
kindly sign  and return  to us  the enclosed  copies hereof,  whereupon it  will
become  a binding  agreement between  the Company  and the  several Underwriters
including you, all in accordance with its terms.
 
                                          Very truly yours,
 
                                          UroCor, Inc.
 
                                          By:
                                          --------------------------------------
                                                    William A. Hagstrom,
                                                   CHAIRMAN OF THE BOARD,
                                                PRESIDENT AND CHIEF EXECUTIVE
                                                           OFFICER
 
The foregoing  Underwriting  Agreement
is hereby confirmed and accepted by us
in San Francisco, California as of the
date first above written.
 
MONTGOMERY SECURITIES
VOLPE, WELTY & COMPANY
Acting   as  Representatives   of  the
several  Underwriters  named  in   the
attached Schedule A.
 
By MONTGOMERY SECURITIES
 
By:
- --------------------------------------
                 Partner
 
                                       20
<PAGE>
                                   SCHEDULE A
 
<TABLE>
<CAPTION>
                                                                                                   NUMBER OF FIRM
                                                                                                    COMMON SHARES
NAME OF UNDERWRITER                                                                                TO BE PURCHASED
- -------------------------------------------------------------------------------------------------  ---------------
<S>                                                                                                <C>
Montgomery Securities............................................................................
Volpe, Welty & Company...........................................................................
                                                                                                   ---------------
    TOTAL........................................................................................       2,800,000
                                                                                                   ---------------
                                                                                                   ---------------
</TABLE>
 
                                       21
<PAGE>
                                   EXHIBIT A
                       FORM OF OPINION OF COMPANY COUNSEL
 
    (1)  The Company  has been  duly incorporated and  is validly  existing as a
corporation under the laws  of the State of  Delaware, with corporate power  and
authority  under  such laws  to own,  lease  and operate  its properties  and to
conduct its  business  as  described  in  the  Registration  Statement  and  the
Prospectus.  To such counsel's knowledge, the  Company is qualified as a foreign
corporation to transact  business in and  is in  good standing in  the State  of
Oklahoma.
 
    (2)  The Company  has an authorized  capitalization of  26,579,759 shares of
capital stock, consisting of 20,000,000 shares of Common Stock, 6,000,000 shares
of preferred stock, $.01  par value per share  (the "Preferred Stock"),  513,093
shares  of Class  A Stock, $.01  par value per  share (the "Class  A Stock") and
66,666 shares of  Class B Stock,  $.01 par  value per share  ("Class B  Stock").
Immediately  prior  to  the closing  of  the  offering, upon  conversion  of all
outstanding shares of  Preferred Stock,  Class A Stock  and Class  B Stock  into
shares  of Common Stock, there will be issued and outstanding          shares of
Common Stock and no other shares of capital stock of the Company will be  issued
and outstanding.
 
    (3)  All of  the issued and  outstanding shares of  Common Stock outstanding
prior to the issuance of the Firm  Common Shares and any Optional Common  Shares
pursuant  to this Agreement have been duly authorized and validly issued and are
fully paid and nonassessable and none of  them have been issued in violation  of
any  preemptive right under the Delaware General Corporation Law (the "DGCL") or
the Company's  Restated  Certificate  of Incorporation  or,  to  such  counsel's
knowledge, any other similar right.
 
    (4)  The Firm Common Shares and any  Optional Common Shares, when issued and
delivered in accordance  with the  provisions of  this Agreement,  will be  duly
authorized,  validly issued, fully paid and  nonassessable and none of them will
have been issued  in violation of  any preemptive  right under the  DGCL or  the
Company's Restated Certificate of Incorporation or, to such counsel's knowledge,
any  other similar  right. The certificates  evidencing the Common  Shares to be
delivered under this Agreement are in due and proper form under the DGCL.
 
    (5) Except as disclosed  in the Prospectus, such  counsel knows of no  other
outstanding  options, warrants  or rights  calling for  the issuance  of, and no
commitment, other  than pursuant  to the  1992  Plan, to  issue, any  shares  of
capital  stock of the  Company or any security  convertible into or exchangeable
for capital stock of the  Company. Such counsel does not  know of any holder  of
any  securities of  the Company who  has the right  to have any  Common Stock or
other securities of the  Company included in the  Registration Statement or  the
right,  as a  result of  the filing  of the  Registration Statement,  to require
registration under the Act of any shares of Common Stock or other securities  of
the Company, with rights have not previously been waived.
 
    (6)  No consent, approval, authorization or  other action or filing with any
federal or state court or governmental authority was required for the  execution
and  delivery  of  this  Agreement  by  the  Company  or  is  required  for  the
consummation by the Company  of the transactions which  are the subject of  this
Agreement,  except such as have been obtained under the Act and the Exchange Act
and such  as may  be required  under  state securities  laws (except  that  such
counsel  need express no  opinion as to the  securities or Blue  Sky laws of any
state) in  connection with  the purchase  and distribution  of the  Firm  Common
Shares and any Optional Common Shares by you and except such as will not, if not
obtained,  have  a material  adverse effect  on the  transactions which  are the
subject of this Agreement.
 
    (7) Execution and delivery by the Company of, and performance by the Company
of its agreements in, this Agreement, will not (a) breach or result in a default
under any indenture,  mortgage, deed of  trust, loan agreement,  lease or  other
agreement  or instrument to which the Company is a party or to which the Company
or any of its properties are subject, in each case, which are filed as  exhibits
to   the  Registration  Statement,  (b)  violate  the  Restated  Certificate  of
Incorporation or By-laws of the Company  or any judgment, decree or order  known
to such counsel of any court or governmental
 
                                      A-1
<PAGE>
agency  or  body applicable  to the  Company or  any of  its properties,  or (c)
violate any  applicable provisions  of any  state or  federal statutory  law  or
regulation  (except  that  such  counsel  need  express  no  opinion  as  to the
securities or Blue Sky  laws of any  state and no opinion  as to the  anti-fraud
provisions of the federal or state securities laws).
 
    (8)  This  Agreement has  been duly  authorized  by all  necessary corporate
action on the part of  the Company and has been  duly executed and delivered  by
the Company and is enforceable against the Company in accordance with its terms,
except as enforceability may be limited by applicable equitable principles or by
bankruptcy,  insolvency, moratorium, reorganization or similar laws from time to
time in effect  relating to or  affecting the enforcement  of creditors'  rights
generally  and  by  general  equitable principles  (regardless  of  whether such
enforceability is considered in a proceeding in equity or at law) and except  as
enforceability  of the  rights to indemnity  and contribution  contained in this
Agreement may be limited by federal  or state laws and public policy  underlying
such laws.
 
    (9)  All filings required by Rule 424  and 430A of the Regulations have been
made.
 
    (10) The Registration Statement and  the Prospectus, as of their  respective
effective  or issue dates (except for the financial statements and the notes and
schedules thereto and the auditor's report thereon, and any other information of
a financial, numerical, statistical or  accounting nature set forth or  referred
to  therein, as to which such counsel need express no opinion), each appeared on
its face  to  be  appropriately  responsive in  all  material  respects  to  the
requirements of the Act and the Regulations.
 
    (11)  To such counsel's knowledge, there are no contracts or other documents
required to be disclosed in the  Registration Statement or the Prospectus  other
than  those  disclosed therein  and there  are no  contracts or  other documents
required to be filed as exhibits to the Registration Statement other than  those
filed as exhibits thereto.
 
    (12)  Except as  described in the  Prospectus, to  such counsel's knowledge,
there is not  pending or  threatened any  action, suit,  proceeding, inquiry  or
investigation  to which the Company  is a party or to  which the property of the
Company is subject  which are  of such  a nature that  they are  required to  be
disclosed in the Prospectus.
 
    (13)  The information in the Prospectus  under the captions "Risk Factors --
Uncertainties  Related  to  Third-Party  Reimbursement;  Potential  Health  Care
Reform",  "Business -- Third-Party  Reimbursement" and under  the first and last
paragraphs of "Risk Factors -- Government Regulation" and second through  eighth
paragraphs  of  "Business --  Government Regulation",  to  the extent  that they
constitute matters of law, summaries of legal matters or legal conclusions, have
been reviewed by such counsel and are correct in all material respects.
 
    (14) The Company is  not an "investment company"  within the meaning of  the
Investment Company Act of 1940, as amended.
 
    To the extent deemed advisable by such counsel, it may rely as to matters of
fact  on certificates of  officers of the Company,  on certificates or facsimile
transmissions of government officials and representations of the Company in this
Agreement.
 
    Such counsel shall  state that it  has acted  as counsel to  the Company  in
connection with certain aspects of the transactions relating to the issuances by
the Company of the shares of Common Stock, promissory notes, preferred stock and
warrants described in Item 15 of the Registration Statement, and such counsel is
aware that the Company issued such securities in reliance on exemptions from the
registration  requirements afforded by  Section 4(2) of the  Act or Regulation D
promulgated under  the  Act.  Based upon  a  review  of the  offering  or  other
materials  used in connection with such transactions and the representations and
other information provided by  offerees (or their  representatives, as the  case
may  be) to whom such securities were  delivered and, assuming compliance by the
Company with advice previously given by such counsel to the Company as to offers
of its securities to persons other
 
                                      A-2
<PAGE>
than those who were  parties to the aforementioned  transactions, no facts  have
come  to such  counsel's attention  to cause such  counsel to  believe that such
reliance by  the  Company was  not  justified as  to  each of  the  transactions
pursuant to which such securities were offered or issued.
 
    Such  counsel also shall state whether it has been advised by the Commission
that the Registration Statement is effective under the Act and, whether, to such
counsel's  knowledge,  any  stop  order  suspending  the  effectiveness  of  the
Registration Statement has been issued by the Commission or proceedings for that
purpose instituted by the Commission.
 
    In  addition, such counsel shall state that such counsel has participated in
conferences with officers and other representatives of the Company, its  counsel
and  representatives of  the independent public  accountants of  the Company and
with your representatives, at which conferences the contents of the Registration
Statement and the Prospectus  were discussed; and although  such counsel is  not
passing   upon  and  does  not  assume  any  responsibility  for  the  accuracy,
completeness or  fairness  of  the  statements  contained  in  the  Registration
Statement  or  the  Prospectus  and  makes  no  representation  that  they  have
independently  verified  the   accuracy,  completeness  or   fairness  of   such
statements,  on the basis of the foregoing and the information disclosed to such
counsel (relying as to materiality to a large extent upon the officers and other
representatives of the Company and your representatives), (i) no facts have come
to such counsel's  attention that would  lead such counsel  to believe that  the
Registration  Statement, as of the time it was declared effective under the Act,
contained any untrue statement of a material fact or omitted to state a material
fact required to be stated therein or  necessary in order to make the  statement
therein  not misleading (it  being understood that such  counsel need express no
view with  respect to  the  financial statements  and  the notes  and  schedules
thereto  and  the  auditor's report  thereon,  and  any other  information  of a
financial, numerical, statistical or accounting nature set forth or referred  to
in  the Registration Statement or any exhibits  thereto), and (ii) no facts have
come to such counsel's  attention that would lead  such counsel to believe  that
the  Prospectus, as of the time if  was filed with the Commission, contained any
untrue statement of a material fact or omitted to state a material fact required
to be stated therein or necessary in  order to the make the statements  therein,
in the light of the circumstances under which they were made, not misleading (it
being  understood that  such counsel  need express no  view with  respect to the
financial statements  and the  notes  and schedules  thereto and  the  auditor's
report thereon, and any other information of a financial, numerical, statistical
or accounting nature set forth or referred to in the Prospectus).
 
                                      A-3

<PAGE>
<TABLE>
<S>                                            <C>
 
<CAPTION>
                                                               COMMON STOCK
<S>                                            <C>
</TABLE>
                                    UROCOR, INC.
<TABLE>
<S>                                            <C>
       C
 
<CAPTION>
    
</TABLE>
<TABLE>
<S>                                            <C>
      THIS CERTIFICATE IS TRANSFERABLE
            IN NEW YORK, NEW YORK
 
<CAPTION>
                                                             CUSIP 91727P 10 5
 
<S>                                          <C>
                                                      SEE REVERSE FOR CERTAIN
                                                             DEFINITIONS
                                      
 
</TABLE>
 
    THIS CERTIFIES THAT
 
    is the owner of
 
FULLY PAID AND NON-ASSESSABLE SHARES OF COMMON STOCK, PAR VALUE $.01 PER SHARE,
                                       OF
 
UROCOR, INC., transferable on the books of the Corporation by the holder hereof,
in  person or  by duly authorized  attorney, upon surrender  of this Certificate
properly endorsed or accompanied by a proper assignment. This Certificate is not
valid until countersigned and registered by the Transfer Agent and Registrar.
 
    IN WITNESS WHEREOF, the Corporation has caused this certificate to be signed
in facsimile by its duly authorized officers and the facsimile corporate seal to
be duly affixed hereto.
 
<TABLE>
<S>                                                 <C>
DATED:
 
    /s/ William A. Hagstrom                          /s/ Socrates H. Choumbakos
            PRESIDENT                                          SECRETARY
</TABLE>

                                     [LOGO] 
<PAGE>
 
<TABLE>
<S>                                                                         <C>
                                                                            COUNTERSIGNED AND REGISTERED:
 
                                                                                             AMERICAN STOCK TRANSFER & TRUST COMPANY
                                                                                                                      TRANSFER AGENT
                                                                                                                       AND REGISTRAR
                                                                            BY
 
                                                                            AUTHORIZED SIGNATURE
</TABLE>
<PAGE>
                                  UROCOR, INC.
 
    The  corporation  will furnish  without charge  to  each stockholder  who so
requests the  powers,  designations,  preferences  and  relative  participating,
optional  or other special rights  of each class of  stock or series thereof and
the qualifications,  limitations  or  restrictions of  such  preferences  and/or
rights.
 
    The  following abbreviations,  when used in  the inscription on  the face of
this certificate, shall  be construed as  though they were  written out in  full
according to applicable laws or regulations:
 
<TABLE>
<S>         <C>        <C>                        <C>                    <C>                      <C>
TEN COM        --      as tenants in common       UNIF GIFT MIN ACT--    ..............Custodian  ........... 
TEN ENT        --      as tenants by the
                       entireties                                        (Cust)                     (Minor)
JT TEN         --      as joint tenants with                             under Uniform Gifts to Minors Act
                       right                                             ....................................
                       of survivorship and not                           (STATE)
                       as
                       tenants in common
</TABLE>
 
    Additional abbreviations may also be used though not in the above list.
    For Value Received, __________________ hereby sell, assign and transfer unto
 
<TABLE>
<S>                                              <C>
    PLEASE INSERT SOCIAL SECURITY OR OTHER
        IDENTIFYING NUMBER OF ASSIGNEE
</TABLE>
 
________________________________________________________________________________
 (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE)
________________________________________________________________________________
_________________________________________________________________________ Shares
 
of Common Stock represented by the within Certificate, and do hereby irrevocably
constitute and appoint
________________________________________________________________________________
_______________________________________________________________________ Attorney
 
to  transfer the said  stock on the  books of the  within named Corporation with
full power of substitution in the premises.
 
<TABLE>
<S>                          <C>          <C>
Dated,
                                          X____________________________________
NOTICE: THE SIGNATURE(S) TO
THIS ASSIGNMENT MUST CORRE-
SPOND WITH  THE NAME(S)  AS
WRITTEN  UPON  THE  FACE OF
THE  CERTIFICATE  IN  EVERY
PARTICULAR, WITHOUT
ALTERATION  OR  ENLARGEMENT
OR ANY CHANGE WHATEVER.
                                          X_____________________________________
                                          Signature(s) must be guaranteed by a bank, broker or qualified financial
                                           institution.
</TABLE>

<PAGE>


                                 FULBRIGHT & JAWORSKI
                                        L.L.P.
                  A Registered Limited Liability Partnership       Houston
                           1301 McKinney, Suite 5100            Washington, D.C.
                           Houston, Texas  77010-3095              Austin
Telephone: 713/651-5151                                         San Antonio
    Telex: 76-2829                                                 Dallas
Facsimile: 713/651-5246                                           New York
                                                                Los Angeles
                                                                  London
                                                                 Hong Kong

                                     May 10, 1996



UroCor, Inc.
800 Research Parkway
Oklahoma City, Oklahoma 73104

Ladies and Gentlemen:

         We refer to the Registration Statement on Form S-1 (Registration No.
333-3182), as amended (the "Registration Statement"), filed by UroCor, Inc., a
Delaware corporation (the "Company"), with the Securities and Exchange
Commission under the Securities Act of 1933, relating to the offer by the
Company of 2,800,000 shares of the Company's Common Stock, $.01 par value per
share (the "Common Stock"), and up to 420,000 shares of Common Stock, which may
be sold in the event the underwriters for the offering elect to exercise their
over-allotment option.

         As counsel to the Company, we have examined such corporate records,
documents and questions of law as we have deemed necessary or appropriate for
the purposes of this opinion.  In such examinations, we have assumed the
genuineness of signatures and the conformity to the originals of the documents
supplied to us as copies.  As to various questions of fact material to this
opinion, we have relied upon statements and certificates of officers and
representatives of the Company.  Upon the basis of such examination, we advise
you that in our opinion the shares of Common Stock to be offered by the Company
have been duly and validly authorized and, when sold in accordance with the
terms agreed upon in the underwriting agreement, will be legally issued, fully
paid and nonassessable.

         We consent to the filing of this opinion as Exhibit 5.1 to the
Registration Statement and to the reference to this firm under the caption
"Legal Matters" in the prospectus contained therein.  This consent is not to be
construed as an admission that we are a person whose consent is required to be 
filed with the Registration Statement under the provisions of the Securities 
Act of 1933.

                                            Very truly yours,

                                            /S/Fulbright & Jaworski L.L.P.

                                            Fulbright & Jaworski L.L.P.


<PAGE>
                                                            [UROCOR LOGO]
April 3, 1996

Ms. Kathryn L.W. Ingerly
7808 Nile Circle
Arvada, CO 80007

Dear Kathryn:

I am pleased to offer you a position as part of UroCor's Executive Management 
Team. The objective of this letter is to outline the offer to you.

1. Position Title: Vice President, Disease Management Information Systems

2. Position Reports to the President and CEO, Bill Hagstrom.

3. Start Date: April 9, 1996.

4. Base Salary: $4,615 each pay period (or $120,000 annually). Performance 
   and Salary review on the twelfth month of employment.

5. Annual Management Bonus - Up to 30% ($36,000) based on several business 
   and individual accomplishments. In 1995 the management bonus plan consisted 
   of one third Company sales revenue, one third Corporate Financial Performance
   and one third individual attainment of goals and objectives. The 1996 bonus
   plan is still being finalized. Management bonuses are typically paid in March
   or April following the completed calendar year. Individual goals will be
   agreed to by the end of the first quarter following your employment date.
   Bonuses are prorated for the time in the position.

6. Stock Option Participation - Options covering 40,000 shares of common 
   stock, vested equally over the next five years. Vested options may be 
   exercised at any time over a ten year period. Exercise price will be 
   determined by the board in the next two to three weeks and at that time 
   formal issuance will be made.

7. Benefits for which you may be eligible at UroCor, consist of:
   . Term life insurance at two (2) times annual salary (capped at $210,000
     coverage).
   . Disability insurance. (Short and Long Term)
   . Medical and dental insurance for you and your family at monthly premium. 
     You are eligible for this benefit on the first day of the month following
     your 30th work day.
   . 401K retirement plan - self directed, no Company match at this time
   . Two weeks vacation after 12 months Company service. An additional week 
     will be added to your vacation after one year. Although your vacation 
     accrues throughout your first year prorated to your start date, you will
     be allowed to take vacation at anytime during the year anticipating your
     total accrual. For 1996, your accrual would be seven days vacation. On
     January 1, 1997 you will accrue vacation at the two week rate until your 
     anniversary date at which time your vacation will accrue at three weeks.
   . Paid Company holidays, sick leave and personal time will be described to 
     you during your first few days of employment. Please call Inez Dunn to set 
     up a 30 minute appointment with her during your first few days at 
     UroCor. EXT 4121.


<PAGE>

Every employee is required to sign confidentiality and non-compete agreements 
with UroCor, Inc., Inc. You have agreed to work with UroCor, Inc. in defining
an agreement that will be acceptable and in both your and UroCor's interest
with regard to actual intellectual property brought to UroCor as of April 1996.
It is anticipated that the agreement will be reached within the first month of 
your employment.

Your first 90 days of employment are considered an Introductory Period, and 
during that period you will accrue benefits as described in the Employee 
Manual unless otherwise required by law. Completion of the Introductory 
Period does not guarantee continued employment for any specified period of 
time, nor does it require that a dismissal be based on "cause."

You are guaranteed a three month severance payment for termination without 
"cause". In that event, you would be paid through regular payroll for the three 
months following your termination date.

As an employee of UroCor, you will be provided with a copy of the UroCor 
Employee Manual and insurance booklets which outline our personnel policies 
and benefits program. You will be expected to read these materials 
thoroughly, and sign and return a copy  of the "Receipt & Acknowledgment Of 
UroCor Employee Manual." You will also be required to sign a Non-Compete 
agreement. Any questions regarding UroCor policy, benefits administration or 
eligibility should be directed to Mrs. Lou Carmichael EXT 4120, Director, 
Human Resources or Mrs. Inez Dunn EXT 4121, Coordinator Benefits and Payroll.

Your employment and compensation with UroCor are "at will" in that they can 
be terminated with or without cause, and with or without notice, at any time, 
at the option of either UroCor or yourself, except as otherwise provided by 
law. The terms of this offer letter, therefore, do not and are not intended 
to create either an express and/or implied contract of employment with 
UroCor. No manager or representative of UroCor, other than the President of 
UroCor, has authority to enter into any agreement for employment for any 
specified period of time or to make any agreement or contract to the 
foregoing, and any promises to the contrary may only be relied upon by you if 
they are in writing and signed by the President of UroCor.

Our offer to hire you is contingent upon your submission of satisfactory 
proof of your identity and your legal authorization to work in the United 
States. If you fail to submit this proof, federal law prohibits us from 
hiring you.

I look forward to your response as well as to the opportunity of working with 
you in the future.

Very truly yours,

/s/ William A. Hagstrom

William A. Hagstrom
President, CEO and Chairman,
UroCor, Inc.


<PAGE>
                                                                    EXHIBIT 23.1
 
                   CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS
 
    As  independent  public accountants,  we hereby  consent to  the use  of our
reports and  to  all  references  to our  firm  included  in  this  registration
statement.
 
Oklahoma City, Oklahoma                   ARTHUR ANDERSEN LLP
May 10, 1996


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