MUNICIPAL INVESTMENT TRUST FD INSURED SER 406 DEF ASSET FDS
487, 2000-01-13
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<PAGE>

    AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JANUARY 13, 2000



                                                      REGISTRATION NO. 333-90157

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549
                     -------------------------------------

                                AMENDMENT NO. 1
                                       TO
                                    FORM S-6
                     -------------------------------------

                   FOR REGISTRATION UNDER THE SECURITIES ACT
                    OF 1933 OF SECURITIES OF UNIT INVESTMENT
                        TRUSTS REGISTERED ON FORM N-8B-2

                     -------------------------------------

A. EXACT NAME OF TRUST:
                        MUNICIPAL INVESTMENT TRUST FUND

                              INSURED SERIES--406

                              DEFINED ASSET FUNDS

B. NAME OF DEPOSITOR:


               MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED

                           SALOMON SMITH BARNEY INC.
                            PAINEWEBBER INCORPORATED
                           DEAN WITTER REYNOLDS INC.

C. COMPLETE ADDRESSES OF DEPOSITORS' PRINCIPAL EXECUTIVE OFFICES:


<TABLE>
<S>                        <C>                        <C>
     MERRILL LYNCH,
 PIERCE, FENNER & SMITH
      INCORPORATED
  UNIT INVESTMENT TRUST
        DIVISION
      P.O. BOX 9051
PRINCETON, NJ 08543-9051                              PAINEWEBBER INCORPORATED
                                                         1285 AVENUE OF THE
                                                              AMERICAS
                                                         NEW YORK, NY 10019

SALOMON SMITH BARNEY INC.
      388 GREENWICH
   STREET--23RD FLOOR
   NEW YORK, NY 10013
                                                      DEAN WITTER REYNOLDS INC.
                                                           TWO WORLD TRADE
                                                         CENTER--59TH FLOOR
                                                         NEW YORK, NY 10048
</TABLE>


D. NAMES AND COMPLETE ADDRESSES OF AGENTS FOR SERVICE:

<TABLE>
<CAPTION>

<S>                        <C>                        <C>
  TERESA KONCICK, ESQ.
      P.O. BOX 9051
PRINCETON, NJ 08543-9051
                                                          ROBERT E. HOLLEY
                                                          1200 HARBOR BLVD.
                                                         WEEHAWKEN, NJ 07087

</TABLE>
<PAGE>


                           DEFINED ASSET FUNDS--REGISTERED TRADEMARK--

                           ----------------------------------------------------


                           MUNICIPAL INVESTMENT TRUST FUND
                           INSURED SERIES--406
                           (A UNIT INVESTMENT TRUST)
                           -  PORTFOLIO OF INSURED LONG-TERM MUNICIPAL BONDS
                           -  DESIGNED TO BE FREE OF REGULAR FEDERAL INCOME TAX
                           -  INCOME DISTRIBUTIONS TWICE A YEAR

SPONSOR:
MERRILL LYNCH,             -----------------------------------------------------
PIERCE, FENNER & SMITH     The Securities and Exchange Commission has not
INCORPORATED               approved or disapproved these Securities or passed
SALOMON SMITH BARNEY INC.  upon the adequacy of this prospectus. Any
PAINEWEBBER INCORPORATED   representation to the contrary is a criminal offense.
DEAN WITTER REYNOLDS INC.  Prospectus dated January 13, 2000.

<PAGE>
- --------------------------------------------------------------------------------


Defined Asset Funds--Registered Trademark--


Defined Asset Funds-Registered Trademark- is America's oldest and largest family
of unit investment trusts with over $160 billion sponsored in the last 28 years.
Our family of Defined Funds helps investors work toward their financial goals
with a full range of quality investments, including municipal, corporate and
government bond portfolios, as well as domestic and international equity
portfolios.


Defined Asset Funds offer a number of advantages:
  - Fixed portfolio: Defined Funds follow a buy and hold investment strategy;
    funds are not managed and portfolio changes are limited.
  - Preselected Portfolios: We choose the stocks and bonds in advance, so you
    know what you're investing in.
  - Professional research: Our dedicated research team seeks out stocks or bonds
    appropriate for a particular fund's objectives.
  - Ongoing supervision: We monitor each portfolio on an ongoing basis.
No matter what your investment goals, tolerance for risk or time horizon,
there's probably a Defined Asset Fund that suits your investment style. Your
financial professional can help you select a Defined Asset Fund that works best
for your investment portfolio.


<TABLE>
<S>                                    <C>
CONTENTS
                                       PAGE
                                        --
Risk/Return Summary and Portfolio....    3
What You Can Expect From Your
  Investment.........................    7
  Income Twice a Year................    7
  Return Figures.....................    7
  Records and Reports................    7
The Risks You Face...................    8
  Interest Rate Risk.................    8
  Call Risk..........................    8
  Reduced Diversification Risk.......    8
  Liquidity Risk.....................    8
  Concentration Risk.................    8
  Bond Quality Risk..................    9
  Insurance Related Risk.............    9
  Litigation and Legislation Risks...    9
Selling or Exchanging Units..........    9
  Sponsors' Secondary Market.........   10
  Selling Units to the Trustee.......   10
  Exchange Option....................   11
How The Fund Works...................   11
  Pricing............................   11
  Evaluations........................   11
  Income.............................   11
  Expenses...........................   12
  Portfolio Changes..................   12
  Fund Termination...................   13
  Certificates.......................   13
  Trust Indenture....................   13
  Legal Opinion......................   14
  Auditors...........................   14
  Sponsors...........................   14
  Trustee............................   15
  Underwriters' and Sponsors'
    Profits..........................   15
  Public Distribution................   15
  Code of Ethics.....................   15
  Advertising and Sales Literature...   15
Taxes................................   16
Supplemental Information.............   17
Financial Statements.................   18
  Report of Independent Accountants..   18
  Statement of Condition.............   18
</TABLE>


                                       2
<PAGE>
- --------------------------------------------------------------------------------

RISK/RETURN SUMMARY


<TABLE>
<C>  <S>
 1.  WHAT IS THE FUND'S OBJECTIVE?
     The Fund seeks interest income that is
     exempt from regular federal income taxes
     by investing in a fixed portfolio
     consisting primarily of insured,
     long-term municipal revenue bonds.

 2.  WHAT ARE MUNICIPAL REVENUE BONDS?
     Municipal revenue bonds are bonds issued
     by states, municipalities and public
     authorities to finance the cost of
     buying, building or improving various
     projects intended to generate revenue,
     such as airports, health care
     facilities, housing and municipal
     electric, water and sewer utilities.
     Generally, payments on these bonds
     depend solely on the revenues generated
     by the projects, excise taxes or state
     appropriations, and are not backed by
     the government's taxing power.

 3.  WHAT IS THE FUND'S INVESTMENT STRATEGY?

  -  The Fund plans to hold to maturity 10
     insured, long-term tax-exempt municipal
     bonds with an aggregate face amount of
     $10,000,000, and some short-term bonds
     reserved to pay the deferred sales
     charge. The Fund is a unit investment
     trust which means that, unlike a mutual
     fund, the Fund's portfolio is not
     managed.
  -  The bonds are rated AAA or Aaa by
     Standard & Poor's, Moody's or Fitch.
  -  Most of the bonds cannot be called for
     several years, and after that they can
     be called at a premium declining over
     time to par value. Some bonds may be
     called earlier at par for extraordinary
     reasons.
  -  100% of the bonds are insured by AAA or
     Aaa-rated insurance companies that
     guarantee timely payments of principal
     and interest on the bonds (but not Fund
     units or the market value of the bonds
     before they mature).

     The Portfolio consists of municipal
     bonds of the following types:
</TABLE>



<TABLE>
  -  Airports/Ports/Highways              10%
<C>  <S>
  -  General Obligation                   10%
  -  Hospitals/Health Care                40%
  -  Housing                              10%
  -  Lease Rental                         20%
  -  Municipal Water/Sewer Utilities        9%
  -  State/Local Government Supported     1%
</TABLE>


<TABLE>
<C>  <S>
 4.  WHAT ARE THE SIGNIFICANT RISKS?

     YOU CAN LOSE MONEY BY INVESTING IN THE
     FUND. THIS CAN HAPPEN FOR VARIOUS
     REASONS, INCLUDING:

  -  Rising interest rates, an issuer's
     worsening financial condition or a drop
     in bond ratings can reduce the price of
     your units.
  -  Because the Fund is concentrated in
     hospital/health care bonds, adverse
     developments in this sector may
     adversely affect the value of your
     units.
  -  Assuming no changes in interest rates,
     when you sell your units, they will
     generally be worth less than your cost
     because your cost included a sales fee.
  -  The Fund will receive early returns of
     principal if bonds are called or sold
     before they mature. If this happens your
     income will decline and you may not be
     able to reinvest the money you receive
     at as high a yield or as long a
     maturity.

 5.  IS THIS FUND APPROPRIATE FOR YOU?

     Yes, if you want income free of regular
     federal income tax. You will benefit
     from a professionally selected and
     supervised portfolio whose risk is
     reduced by investing in insured bonds of
     several different issuers.
     The Fund is NOT appropriate for you if
     you want a speculative investment that
     changes to take advantage of market
     movements, if you do not want a
     tax-advantaged investment or if you
     cannot tolerate any risk.
</TABLE>

                                       3
<PAGE>
- --------------------------------------------------------------------------------
                               Defined Portfolio
- -------------------------------------------------------------------


Insured Series--406


<TABLE>
<CAPTION>
                                                                          RATING             COST
PORTFOLIO TITLE                                COUPON    MATURITY (1)  OF ISSUES (2)     TO FUND (3)
<S>                                            <C>       <C>           <C>             <C>
- -------------------------------------------------------------------------------------------------------
</TABLE>


AIRPORTS/PORTS/HIGHWAYS (10%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
 1. $1,000,000 Massachusetts Tpke. Auth.,       5.00%     01/01/2039   AAA             $   809,600.00
    Metro. Hwy. Sys. Rev. Bonds, Ser. 1999 A
    (AMBAC Ins.)
</TABLE>



GENERAL OBLIGATION (10%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
 2. $1,000,000 City of Chicago, IL, G.O.        5.25      01/01/2028   AAA                 868,580.00
    Bonds, Proj. and Rfdg. Ser. 1998
    (Financial Guaranty Ins.)

 3. $100,000 Whatcom Cnty., WA, Bellingham      4.00      12/01/2002   AAA                  97,863.00
    Sch. Dist. No. 501, Unltd. Tax G.O. and
    Rfdg. Bonds, 1999 (FSA Ins.)(4)
</TABLE>



HOSPITALS/HEALTH CARE (40%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
 4. $65,000 The Fulton-Dekalb, GA, Hosp.        5.00      01/01/2001   AAA                  65,611.00
    Auth., Rev. Rfdg. Certs., Ser. 1993 (MBIA
    Ins.) (4)

 5. $1,065,000 Iowa Fin. Auth., Hosp. Rev.      5.75      08/15/2029   AAA                 986,775.75
    Bonds (Mercy Med. Ctr. Proj.), Ser. 1999
    (FSA Ins.)

 6. $1,000,000 Massachusetts Hlth. and Educl.   5.00      07/01/2027   AAA                 819,980.00
    Facs. Auth., Hallmark Hlth. Sys. Issue,
    Rev. Bonds, Ser. A (FSA Ins.)

 7. $5,000 Dormitory Auth. of the State of     4.375      07/01/2001   AAA                   4,991.10
    New York, New Island Hosp. Ins. Rev.
    Bonds, Ser. 1999 A (AMBAC Ins.) (4)

 8. $1,000,000 Bell Cnty. Hlth. Fac. Dev.      6.125      08/15/2023   AAA                 984,610.00
    Corp., TX, Hosp. Rev. Bonds (Scott &
    White Mem. Hosp. and Scott, Sherwood, &
    Brindley Foundation Proj.), Ser. 2000 A
    (MBIA Ins.)

 9. $1,000,000 Washington Hlth. Care            5.00      11/15/2028   AAA                 811,130.00
    Fac.Auth., Rev. Bonds (PeaceHealth), Ser.
    1998 (MBIA Ins.)
</TABLE>



HOUSING (10%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
10. $1,000,000 Alaska Hsg. Fin. Corp., Gen.     6.10      12/01/2037   AAA                 971,190.00
    Mtge. Rev. Bonds, Ser. 1997 A (MBIA Ins.)
</TABLE>



LEASE RENTAL (20%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
11. $1,000,000 Board of Supervisors of the      6.25      09/01/2029   AAA               1,008,130.00
    Univ. of Louisiana Sys., Lease Rev. Bonds
    (Univ. of Louisiana at Lafayette
    Cajundome Conv. Ctr. Proj.), Ser. 2000
    (MBIA Ins.)

12. $1,000,000 Washoe Cnty., NV, G.O. Conv.     6.40      07/01/2029   AAA               1,000,000.00
    Ctr. Current Interest Bonds (Reno-Sparks
    Conv. & Visitors Auth.), Ser. 1999 A (FSA
    Ins.)
</TABLE>



MUNICIPAL WATER/SEWER UTILITIES (9%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
13. $935,000 Utah Wtr. Fin. Agy., Rev. Bonds    5.50      10/01/2029   AAA                 840,714.60
    (Pooled Loan Financing Prog.), Ser.
    1999 A (AMBAC Ins.)
</TABLE>



STATE/LOCAL GOVERNMENT SUPPORTED (1%):



<TABLE>
<S>                                            <C>       <C>          <C>             <C>
14. $5,000 The Gloucester Cnty., NJ, Imp.       4.30      12/01/2002   AAA                   4,959.65
    Auth., Cnty. Gtd. Lease Rev. Bonds, Ser.
    1999 C (FSA Ins.) (4)
                                                                                       --------------
                                                                                       $ 9,274,135.10
                                                                                       ==============
</TABLE>


- ----------------------------

(1)  Approximately 10% of the long-term bonds are callable in 2007, 31% are
     callable in 2008, and the remaining long-term bonds are callable in 2009
     and later. Some bonds could be called earlier under extraordinary
     circumstances.

(2)  All ratings are by Standard & Poor's Ratings Group unless followed by
     "(m)", which indicates a Moody's Investors Service rating or by "(f)",
     which indicates a Fitch IBCA rating. An AAA rating indicates highest
     quality bonds with a very strong capacity to pay interest and repay
     principal.

(3)  Approximately 10% of the bonds were deposited at a premium, 10% at par, and
     80% at a discount from par. Sponsors' profit on deposit was $74,745.30.

(4)  The interest and principal on these bonds will be used to pay the deferred
     sales charge obligations of the investors, and these amounts are not
     included in the calculation of Estimated Current and Long Term Returns.
                        --------------------------------

                   PLEASE NOTE THAT IF THIS PROSPECTUS IS USED AS A PRELIMINARY
                   PROSPECTUS
                   FOR A FUTURE FUND IN THIS SERIES, THE PORTFOLIO WILL CONTAIN
                   DIFFERENT
                   BONDS FROM THOSE DESCRIBED ABOVE.
<PAGE>
- --------------------------------------------------------------------------------
RISK/RETURN SUMMARY (CONTINUED)

<TABLE>
<C>  <S>
     DEFINING YOUR INCOME AND
     ESTIMATING YOUR RETURN
</TABLE>


<TABLE>
<C>  <S>                                            <C>
     WHAT YOU MAY EXPECT (RECORD DAY: 10th day of
     each August and February)
     First payment per 1,000 units (8/25/00)         $31.59
     Regular Semi-Annual Income per 1,000 units
     (each August and February beginning 2/25/01):   $27.47
     Annual Income per 1,000 units:                  $54.95

     THESE FIGURES ARE ESTIMATES ON THE BUSINESS DAY BEFORE
     THE INITIAL DATE OF DEPOSIT; ACTUAL PAYMENTS MAY VARY.
</TABLE>



<TABLE>
<C>  <S>                                              <C>
     Estimated Current Return                           5.85%
     Estimated Long Term Return                         6.01%

     THESE RETURNS WILL VARY (SEE PAGE 7)
</TABLE>


<TABLE>
<C>  <S>
 6.  WHAT ARE THE FUND'S FEES AND EXPENSES?

     This table shows the costs and expenses
     you may pay, directly or indirectly, when
     you invest in the Fund.

     INVESTOR FEES

     Maximum Sales Fee (Load) on new
     purchases (as a percentage of
     $1,000 invested)                2.90%

     You will pay an up-front sales fee of
     1.00%, as well as a total deferred sales
     fee of $19.00 per 1,000 units ($2.38 per
     1,000 units quarterly in the first year
     and $2.37 per 1,000 units quarterly in
     the second year). Employees of some of
     the Sponsors and their affiliates may be
     charged a reduced sales fee of no less
     than $5.00 per 1,000 Units.

     The maximum sales fee is reduced if you
     invest at least $100,000, as follows:
</TABLE>

<TABLE>
<CAPTION>
                               YOUR MAXIMUM
                                SALES FEE
          IF YOU INVEST:         WILL BE:
          --------------       ------------
<C>  <S>                       <C>
     Less than $100,000            2.90%
     $100,000 to $249,999          2.65%
     $250,000 to $499,999          2.40%
     $500,000 to $999,999          2.15%
     $1,000,000 and over           1.90%

     Maximum Exchange Fee          1.90%
</TABLE>

<TABLE>
<C>  <S>
     ESTIMATED ANNUAL FUND OPERATING EXPENSES
</TABLE>


<TABLE>
<CAPTION>
                                      AS A % OF        AMOUNT
                                       $1,000        PER 1,000
                                      INVESTED         UNITS
                                      ---------      ---------
<C>  <S>                              <C>            <C>
                                       .068  %         $0.63
     Trustee's Fee
                                       .049  %         $0.46
     Portfolio Supervision,
     Bookkeeping and
     Administrative Fees
       (including updating
     expenses)
                                       .014  %         $0.13
     Evaluator's Fee
                                       .023  %         $0.22
     Other Operating Expenses
                                      -------          -----
                                       .154  %         $1.44
     TOTAL
</TABLE>



<TABLE>
<CAPTION>
                                                       AMOUNT
                                                     PER 1,000
                                                       UNITS
                                                     ---------
<C>  <S>                                        <C>
                                                       $2.00
     ORGANIZATION COSTS (deducted from
     Fund assets at the close of the
     initial offering period)
</TABLE>


<TABLE>
<C>  <S>
     The Sponsors historically paid updating
     expenses.

     EXAMPLE
     This example may help you compare the cost of
     investing in the Fund to the cost of investing
     in other funds.
     The example assumes that you invest $10,000 in
     the Fund for the periods indicated and sell all
     your units at the end of those periods. The
     example also assumes a 5% return on your
     investment each year and that the Fund's
     operating expenses stay the same. Although your
     actual costs may be higher or lower, based on
     these assumptions your costs would be:
</TABLE>


<TABLE>
<S>  <C>     <C>      <C>      <C>
     1 Year  3 Years  5 Years  10 Years
      $326    $359     $396      $505
</TABLE>



<TABLE>
<C>  <S>
     You will pay the following expenses if you do
     not sell your units:
</TABLE>



<TABLE>
<S>  <C>     <C>      <C>      <C>
     1 Year  3 Years  5 Years  10 Years
      $231    $359     $396      $505
</TABLE>



<TABLE>
<C>  <S>
 7.  HOW HAVE SIMILAR FUNDS PERFORMED IN THE
     PAST?
     IN THE FOLLOWING CHART WE SHOW PAST
     PERFORMANCE OF PRIOR MUNICIPAL INSURED
     SERIES, WHICH HAD THE SAME INVESTMENT
     OBJECTIVES, STRATEGIES AND TYPES OF BONDS
     AS THIS FUND. THESE PRIOR SERIES DIFFERED
     IN THAT THEY CHARGED A HIGHER SALES FEE.
     These prior Insured Series were offered
     between January 5, 1988 and October 17,
     1996 and were outstanding on September 30,
     1999. OF COURSE, PAST PERFORMANCE OF PRIOR
     SERIES IS NO GUARANTEE OF FUTURE RESULTS
     OF THIS FUND.
</TABLE>


<TABLE>
<C>  <S>
     AVERAGE ANNUAL COMPOUND TOTAL RETURNS
     FOR PRIOR SERIES
     REFLECTING ALL EXPENSES. FOR PERIODS ENDED
     9/30/99.
</TABLE>

 -------------------------------------------------------------------

<TABLE>
 High                    1.40%     6.67%     6.01%     2.72%     7.86%     6.60%
 <S>                    <C>       <C>       <C>       <C>       <C>       <C>
 Average                 -2.36      5.05      5.72     -0.41      6.11      6.31
 Low                     -7.31      2.86      5.55     -4.69      3.63      6.14
</TABLE>

 -----------------------------------------------------------

<TABLE>
 <S>                    <C>       <C>       <C>       <C>       <C>       <C>
 Average
 Sales fee               2.04%     5.22%     5.82%
</TABLE>

 -----------------------------------------------------

NOTE: ALL RETURNS REPRESENT CHANGES IN UNIT PRICE WITH DISTRIBUTIONS REINVESTED
 INTO THE MUNICIPAL FUND INVESTMENT ACCUMULATION PROGRAM.

                                       4
<PAGE>


<TABLE>
<C>  <S>
 8.  IS THE FUND MANAGED?
     Unlike a mutual fund, the Fund is not
     managed and bonds are not sold because of
     market changes. Rather, experienced
     Defined Asset Funds financial analysts
     regularly review the bonds in the Fund.
     The Fund may sell a bond if certain
     adverse credit or other conditions exist.

 9.  HOW DO I BUY UNITS?
     You can buy units from any of the
     Sponsors and other broker-dealers. The
     Sponsors are listed later in this
     prospectus. Some banks may offer units
     for sale through special arrangements
     with the Sponsors, although certain legal
     restrictions may apply.

     The minimum investment is $250.

     UNIT PRICE PER 1,000 UNITS        $938.61
     (as of January 12, 2000)

     Unit price is based on the net asset
     value of the Fund plus the up-front sales
     fee. An amount equal to any principal
     cash, as well as net accrued but
     undistributed interest on the unit, is
     added to the unit price. Unit price also
     includes the estimated organization costs
     shown on the previous page. An
     independent evaluator prices the bonds at
     3:30 p.m. Eastern time every business
     day. Unit price changes every day with
     changes in the prices of the bonds in the
     Fund.

     UNIT PAR VALUE                      $1.00
     Unit par value means the total amount of
     money you should generally receive on
     each unit by the termination of the Fund
     (other than interest and premium on the
     bonds). This total amount assumes that
     all bonds in the Fund are either paid at
     maturity or called by the issuer at par
     or are sold by the Fund at par. If you
     sell your units before the Fund
     terminates, you may receive more or less
     than the unit par value.

10.  HOW DO I SELL UNITS?

     You may sell your units at any time to
     any Sponsor or the Trustee for the net
     asset value determined at the close of
     business
     on the date of sale, less any remaining
     deferred sales fee. You will not pay any
     other fee when you sell your units.

11.  HOW ARE DISTRIBUTIONS MADE AND TAXED?

     The Fund pays income twice a year. In the
     opinion of bond counsel when each bond
     was issued, interest on the bonds in this
     Fund is generally 100% exempt from
     regular federal income tax. A portion of
     the income may also be exempt from state
     and local personal income taxes,
     depending on where you live.
     You will also receive principal payments
     if bonds are sold or called or mature,
     when the cash available is more than
     $10.00 per 1,000 units. You will be
     subject to tax on any gain realized by
     the Fund on the disposition of bonds.

12.  WHAT OTHER SERVICES ARE AVAILABLE?

     REINVESTMENT
     You will receive your income in cash
     unless you choose to compound your income
     by reinvesting at no sales fee in the
     Municipal Fund Investment Accumulation
     Program, Inc. This program is an open-end
     mutual fund with a comparable investment
     objective except that those bonds will
     generally not be insured. Income from
     this program will generally be subject to
     state and local income taxes. FOR MORE
     COMPLETE INFORMATION ABOUT THE PROGRAM,
     INCLUDING CHARGES AND FEES, ASK THE
     TRUSTEE FOR THE PROGRAM'S PROSPECTUS.
     READ IT CAREFULLY BEFORE YOU INVEST. THE
     TRUSTEE MUST RECEIVE YOUR WRITTEN
     ELECTION TO REINVEST AT LEAST 10 DAYS
     BEFORE THE RECORD DAY OF AN INCOME
     PAYMENT.

     EXCHANGE PRIVILEGES
     You may exchange units of this Fund for
     units of certain other Defined Asset
     Funds. You may also exchange into this
     Fund from certain other funds. We charge
     a reduced sales fee on exchanges.
</TABLE>


                                       5
<PAGE>
- --------------------------------------------------------------------------------

    TAX-FREE VS. TAXABLE INCOME: A COMPARISON OF TAXABLE AND TAX-FREE YIELDS

<TABLE>
                                      EFFECTIVE
TAXABLE INCOME 2000*                  % TAX                                  TAX-FREE YIELD OF
  SINGLE RETURN      JOINT RETURN     BRACKET      3%        3.5%        4%        4.5%        5%        5.5%        6%
                                                                    IS EQUIVALENT TO A TAXABLE YIELD OF
<S>                <C>                <C>        <C>        <C>        <C>        <C>        <C>        <C>        <C>
- ---------------------------------------------------------------------------------------------------------------------------
$      0- 26,250   $      0- 43,850    15.00       3.53       4.12       4.71       5.29       5.88       6.47       7.06
- ---------------------------------------------------------------------------------------------------------------------------
$ 26,251- 63,550   $ 43,851-105,950    28.00       4.17       4.86       5.56       6.25       6.94       7.64       8.33
- ---------------------------------------------------------------------------------------------------------------------------
$ 63,551-132,600   $105,951-161,450    31.00       4.35       5.07       5.80       6.52       7.25       7.97       8.70
- ---------------------------------------------------------------------------------------------------------------------------
<S>                <C>                <C>        <C>        <C>        <C>        <C>        <C>        <C>        <C>
$132,601-288,350   $161,451-288,350    36.00       4.69       5.47       6.25       7.03       7.81       8.59       9.38
- ---------------------------------------------------------------------------------------------------------------------------
<S>                <C>                <C>        <C>        <C>        <C>        <C>        <C>        <C>        <C>
  OVER $288,350    OVER $288,350       39.60       4.97       5.79       6.62       7.45       8.28       9.11       9.93
- ---------------------------------------------------------------------------------------------------------------------------
<S>                <C>                <C>        <C>        <C>        <C>        <C>        <C>        <C>        <C>

<S>                <C>
TAXABLE INCOME 20
  SINGLE RETURN     6.5%
                      IS
                   EQUIVALENT
                     TO A
                   TAXABLE
                   YIELD OF
- -----------------
$      0- 26,250     7.65
- -----------------
$ 26,251- 63,550     9.03
- -----------------
$ 63,551-132,600     9.42
                   --------
- -----------------
$132,601-288,350    10.16
                   --------
- -----------------
  OVER $288,350     10.76
                   --------
- -----------------
</TABLE>



To compare the yield of a taxable security with the yield of a federally
tax-free security, find your taxable income and read across. The table
incorporates 2000 federal income tax rates and assumes that all income would
otherwise be taxed at a U.S. investor's highest tax rate. Yield figures are for
example only.


*Based upon net amount subject to federal income tax after deductions and
exemptions. This table does not reflect the possible effect of other tax
factors, such as alternative minimum tax, personal exemptions, the phase out of
exemptions, itemized deductions, the possible partial disallowance of deductions
or state or local taxation. Consequently, you should consult your own tax
advisers in this regard.

                                       6
<PAGE>
WHAT YOU CAN EXPECT FROM YOUR INVESTMENT

INCOME TWICE A YEAR

The Fund will pay you regular income twice a year. Your income may vary because
of:
  - elimination of one or more bonds from the Fund's portfolio because of calls,
    redemptions or sales;
  - a change in the Fund's expenses; or
  - the failure by a bond's issuer to pay interest.

Changes in interest rates generally will not affect your income because the
portfolio is fixed.

Along with your income, you will receive your share of any available bond
principal.

RETURN FIGURES

We cannot predict your actual return, which will vary with unit price, how long
you hold your investment and changes in the portfolio, interest income and
expenses.

ESTIMATED CURRENT RETURN equals the estimated annual cash to be received from
the bonds in the Fund less estimated annual Fund expenses, divided by the Unit
Price (including the maximum sales fee):

<TABLE>
<S>              <C>  <C>
Estimated Annual         Estimated
Interest Income   -   Annual Expenses
- -------------------------------------
             Unit Price
</TABLE>

ESTIMATED LONG TERM RETURN is a measure of the estimated return over the
estimated life of the Fund. Unlike Estimated Current Return, Estimated Long Term
Return reflects maturities, discounts and premiums of the bonds in the Fund. It
is an average of the yields to maturity (or in certain cases, to an earlier call
date) of the individual bonds in the portfolio, adjusted to reflect the Fund's
maximum sales fee and estimated expenses. We calculate the average yield for the
portfolio by weighting each bond's yield by its market value and the time
remaining to the call or maturity date.

Yields on individual bonds depend on many factors including general conditions
of the bond markets, the size of a particular offering and the maturity and
quality rating of the particular issues. Yields can vary among bonds with
similar maturities, coupons and ratings.

These return quotations are designed to be comparative rather than predictive.

RECORDS AND REPORTS

You will receive:
- - a statement of income payments twice a year;
- - a notice from the Trustee when new bonds are deposited in exchange or
  substitution for bonds originally deposited;
- - an annual report on Fund activity; and
- - annual tax information. THIS WILL ALSO BE SENT TO THE IRS. YOU MUST REPORT THE
  AMOUNT OF TAX-EXEMPT INTEREST RECEIVED DURING THE YEAR.

You may request:
- - copies of bond evaluations to enable you to comply with federal and state tax
  reporting requirements; and
- - audited financial statements of the Fund.

You may inspect records of Fund transactions at the Trustee's office during
regular business hours.

                                       7
<PAGE>
THE RISKS YOU FACE

INTEREST RATE RISK

Investing involves risks, including the risk that your investment will decline
in value if interest rates rise. Generally, bonds with longer maturities will
change in value more than bonds with shorter maturities. Bonds in the Fund are
more likely to be called when interest rates decline. This would result in early
returns of principal to you and may result in early termination of the Fund. Of
course, we cannot predict how interest rates may change.

CALL RISK

Many bonds can be prepaid or "called" by the issuer before their stated
maturity.

Some bonds may be required to be called incrementally pursuant to mandatory
sinking fund provisions.

Also, an issuer might call its bonds during periods of falling interest rates,
if the issuer's bonds have a coupon higher than current market rates.

In extraordinary cases, an issuer might be able to call its bonds if, for
example:
  - it no longer needs the money for the original purpose;
  - the project is condemned or sold;
  - the project is destroyed and insurance proceeds are used to redeem the
    bonds;
  - any related credit support expires and is not replaced; or
  - interest on the bonds become taxable.

If the bonds are called, your income will decline and you may not be able to
reinvest the money you receive at as high a yield or as long a maturity. An
early call at par of a premium bond will reduce your return.

REDUCED DIVERSIFICATION RISK

If many investors sell their units, the Fund will have to sell bonds. This could
reduce the diversification of your investment and increase your share of Fund
expenses.

LIQUIDITY RISK

The bonds will generally trade in the over-the-counter market. We cannot assure
you that a liquid trading market will exist, especially since current law may
restrict the Fund from selling bonds to any Sponsor. The value of the bonds, and
of your investment, may be reduced if trading in bonds is limited or absent.

CONCENTRATION RISK

When a certain type of bond makes up 25% or more of the portfolio, the Fund is
said to be "concentrated" in that bond type, which makes the Fund less
diversified.

Here is what you should know about the Fund's concentration in hospital and
health care bonds:
  - payment for these bonds depends on revenues from private third-party payors
    and government programs, including Medicare and Medicaid, which have
    generally undertaken cost containment measures to limit payments to health
    care providers;
  - hospitals face increasing competition resulting from hospital mergers and
    affiliations;
  - hospitals need to reduce costs as HMOs increase market penetration and
    hospital supply and drug companies raise prices; and
  - hospitals and health care providers are subject to various legal claims by
    patients

                                       8
<PAGE>
    and others and are adversely affected by increasing costs of insurance.
  - many hospitals are aggressively buying physician practices and assuming risk
    contracts to gain market share. If revenues do not increase accordingly,
    this practice could reduce profits.
  - Medicare is changing its reimbursement system for nursing homes. Many
    nursing home providers are not sure how they will be treated. In many cases,
    the providers may receive lower reimbursements and these would have to cut
    expenses to maintain profitability.
  - most retirement/nursing home providers rely on entrance fees for operating
    revenues. If people live longer than expected and turnover is lower than
    budgeted, operating revenues would be adversely affected by less than
    expected entrance fees.

Changes to the portfolio from bond redemptions, maturities and sales may affect
the Fund's concentration over time.

BOND QUALITY RISK

A reduction in a bond's rating may decrease its value and, indirectly, the value
of your investment in the Fund.

INSURANCE RELATED RISK

The bonds are backed by insurance companies (as shown under Defined Portfolio).
Insurance policies generally make payments only according to a bond's original
payment schedule and do not make early payments when a bond defaults or becomes
taxable. Although the federal government does not regulate the insurance
business, various state laws and federal initiatives and tax law changes could
significantly affect the insurance business. The claims-paying ability of the
insurance companies is generally rated AAA by Standard & Poor's or another
nationally recognized rating organization. The insurance company ratings are
subject to change at any time at the discretion of the rating agencies.

LITIGATION AND LEGISLATION RISKS

We do not know of any pending litigation that might have a material adverse
effect upon the Fund.

Future tax legislation could affect the value of the portfolio by:
  - limiting real property taxes,
  - reducing tax rates,
  - imposing a flat or other form of tax, or
  - exempting investment income from tax.

SELLING OR EXCHANGING UNITS

You can sell your units at any time for a price based on net asset value. Your
net asset value is calculated each business day by:
  - ADDING the value of the bonds, net accrued interest, cash and any other Fund
    assets;
  - SUBTRACTING accrued but unpaid Fund expenses, unreimbursed Trustee advances,
    cash held to buy back units or for distribution to investors and any other
    Fund liabilities; and
  - DIVIDING the result by the number of outstanding units.

Your net asset value when you sell may be more or less than your cost because of
sales fees, market movements and changes in the portfolio.

As of the close of the initial offering period, the price you receive will be
reduced to reflect estimated organization costs.

                                       9
<PAGE>
If you sell your units before the final deferred sales fee installment, the
amount of any remaining installments will be deducted from your proceeds.

SPONSORS' SECONDARY MARKET

While we are not obligated to do so, we will buy back units at net asset value
without any other fee or charge other than any remaining deferred sales charge.
We may resell the units to other buyers or to the Trustee. You should consult
your financial professional for current market prices to determine if other
broker-dealers or banks are offering higher prices.

We have maintained a secondary market continuously for over 28 years, but we
could discontinue it without prior notice for any business reason.

SELLING UNITS TO THE TRUSTEE

Regardless of whether we maintain a secondary market, you can sell your units to
the Trustee at any time by sending the Trustee a letter (with any outstanding
certificates if you hold Unit certificates). You must properly endorse your
certificates (or execute a written transfer instrument with signatures
guaranteed by an eligible institution). Sometimes, additional documents are
needed such as a trust document, certificate of corporate authority, certificate
of death or appointment as executor, administrator or guardian.

Within seven days after your request and the necessary documents are received,
the Trustee will mail a check to you. Contact the Trustee for additional
information.

As long as we are maintaining a secondary market, the Trustee will sell your
units to us at a price based on net asset value. If there is no secondary
market, the Trustee may sell your units in the over-the-counter market for a
higher price, but it is not obligated to do so. In that case, you will receive
the net proceeds of the sale.

If the Fund does not have cash available to pay you for units you are selling,
the agent for the Sponsors will select bonds to be sold. Bonds will be selected
based on market and credit factors. These sales could be made at times when the
bonds would not otherwise be sold and may result in your receiving less than the
unit par value and also reduce the size and diversity of the Fund.

If you acquire 25% or more of the outstanding units of the Fund and you sell
units with a value exceeding $250,000, the Trustee may choose to pay you "in
kind" by distributing bonds and cash with a total value equal to the price of
those units. The Trustee will try to distribute bonds in the portfolio pro rata,
but it reserves the right to distribute only one or a few bonds. The Trustee
will act as your agent in an in kind distribution and will either hold the bonds
for your account or sell them as you instruct. You must pay any transaction
costs as well as transfer and ongoing custodial fees on sales of bonds
distributed in kind.

There could be a delay in paying you for your units:
  - if the New York Stock Exchange is closed (other than customary weekend and
    holiday closings);
  - if the SEC determines that trading on the New York Stock Exchange is
    restricted or that an emergency exists making sale or evaluation of the
    bonds not reasonably practicable; and

                                       10
<PAGE>
  - for any other period permitted by SEC order.

EXCHANGE OPTION

You may exchange units of certain Defined Asset Funds for units of this Fund at
a maximum exchange fee of 1.90%. You may exchange units of this Fund for units
of certain other funds at a reduced sales fee if your investment goals change.
To exchange units, you should talk to your financial professional about what
funds are exchangeable, suitable and currently available.

Normally, an exchange is taxable and you must recognize any gain or loss on the
exchange. However, the IRS may try to disallow a loss if the portfolios of the
two funds are not materially different; you should consult your own tax adviser.

We may amend or terminate this exchange option at any time without notice.

HOW THE FUND WORKS

PRICING

The price of a unit includes interest accrued on the bonds, less expenses, from
the initial date of deposit up to, but not including, the settlement date, which
is usually three business days after the purchase date of the unit.

Bonds also carry accrued but unpaid interest up to the initial date of deposit.
To avoid having you pay this additional accrued interest (which earns no return)
when you buy, the Trustee advances this amount to the Sponsors. The Trustee
recovers this advance from interest received on the bonds.

In addition, a portion of the price of a unit consists of cash to pay all or
some of the costs of organizing the Fund including:
  - cost of initial preparation of legal documents;
  - federal and state registration fees;
  - initial fees and expenses of the Trustee;
  - initial audit; and
  - legal expenses and other out-of-pocket expenses.

EVALUATIONS

An independent Evaluator values the bonds on each business day (excluding
Saturdays, Sundays and the following holidays as observed by the New York Stock
Exchange: New Year's Day, Presidents' Day, Martin Luther King, Jr. Day, Good
Friday, Memorial Day, Independence Day, Labor Day, Thanksgiving and Christmas).
Bond values are based on current bid or offer prices for the bonds or comparable
bonds. In the past, the difference between bid and offer prices of publicly
offered tax-exempt bonds has ranged from 0.5% of face amount on actively traded
issues to 3.5% on inactively traded issues; the difference has averaged between
1 and 2%.

INCOME

Interest on any bonds purchased on a when-issued basis or for a delayed delivery
does not begin to accrue until the bonds are delivered to the Fund. The Trustee
may reduce its fee to provide you with tax-exempt income for this non-accrual
period. If a bond is not delivered on time and the Trustee's annual fee and
expenses do not cover the additional accrued interest, we will treat the
contract to buy the bond as failed.

                                       11
<PAGE>
The Trustee credits interest to an Income Account and other receipts to a
Capital Account. The Trustee may establish a Reserve Account by withdrawing from
these accounts amounts it considers appropriate to pay any material liability.
These accounts do not bear interest.

EXPENSES

The Trustee is paid monthly. It also benefits when it holds cash for the Fund in
non-interest bearing accounts. The Trustee may also receive additional amounts:
  - to reimburse the Trustee for the Fund's operating expenses;
  - for extraordinary services and costs of indemnifying the Trustee and the
    Sponsors;
  - costs of actions taken to protect the Fund and other legal fees and
    expenses;
  - expenses for keeping the Fund's registration statement current; and
  - Fund termination expenses and any governmental charges.

The Sponsors are currently reimbursed up to 55 CENTS per $1,000 face amount
annually for providing portfolio supervisory, bookkeeping and administrative
services and for any other expenses properly chargeable to the Fund. Legal,
typesetting, electronic filing and regulatory filing fees and expenses
associated with updating the Fund's registration statement yearly are also now
chargeable to the Fund. While this fee may exceed the amount of these costs and
expenses attributable to this Fund, the total of these fees for all Series of
Defined Asset Funds will not exceed the aggregate amount attributable to all of
these Series for any calendar year. The Fund also pays the Evaluator's fees.
Certain of these expenses were previously paid for by the Sponsors.

The Trustee's, Sponsors' and Evaluator's fees may be adjusted for inflation
without investors' approval.

Quarterly deferred sales fees you owe are paid with interest and principal from
certain bonds. If these amounts are not enough, the rest will be paid out of
distributions to you from the Fund's Capital and Income Accounts.

The Sponsors will pay advertising and selling expenses at no charge to the Fund.
If Fund expenses exceed initial estimates, the Fund will owe the excess. The
Trustee has a lien on Fund assets to secure reimbursement of Fund expenses and
may sell bonds if cash is not available.

PORTFOLIO CHANGES

The Sponsors and Trustee are not liable for any default or defect in a bond; if
a contract to buy any bond fails in the first 90 days of the Fund, we generally
will deposit a replacement tax-exempt bond with a similar yield, maturity,
rating and price.

Unlike a mutual fund, the portfolio is designed to remain intact and we may keep
bonds in the portfolio even if their credit quality declines or other adverse
financial circumstances occur. However, we may sell a bond in certain cases if
we believe that certain adverse credit conditions exist or if a bond becomes
taxable.

If we maintain a secondary market in units but are unable to sell the units that
we buy in the secondary market, we will redeem units, which will affect the size
and composition of the portfolio. Units offered in the secondary

                                       12
<PAGE>
market may not represent the same face amount of bonds that they did originally.

We decide whether or not to offer units for sale that we acquire in the
secondary market after reviewing:
  - diversity of the portfolio;
  - size of the Fund relative to its original size;
  - ratio of Fund expenses to income;
  - current and long-term returns;
  - degree to which units may be selling at a premium over par; and
  - cost of maintaining a current prospectus.

FUND TERMINATION

The Fund will terminate following the stated maturity or sale of the last bond
in the portfolio. The Fund may also terminate earlier with the consent of
investors holding 51% of the units or if total assets of the Fund have fallen
below 40% of the face amount of bonds deposited. We will decide whether to
terminate the Fund early based on the same factors used in deciding whether or
not to offer units in the secondary market.

When the Fund is about to terminate you will receive a notice, and you will be
unable to sell your units after that time. On or shortly before termination, we
will sell any remaining bonds, and you will receive your final distribution. Any
bond that cannot be sold at a reasonable price may continue to be held by the
Trustee in a liquidating trust pending its final sale.

You will pay your share of the expenses associated with termination, including
brokerage costs in selling bonds. This may reduce the amount you receive as your
final distribution.

CERTIFICATES

Certificates for units are issued on request. You may transfer certificates by
complying with the requirements for redeeming certificates, described above. You
can replace lost or mutilated certificates by delivering satisfactory indemnity
and paying the associated costs.

TRUST INDENTURE

The Fund is a "unit investment trust" governed by a Trust Indenture, a contract
among the Sponsors, the Trustee and the Evaluator, which sets forth their duties
and obligations and your rights. A copy of the Indenture is available to you on
request to the Trustee. The following summarizes certain provisions of the
Indenture.

The Sponsors and the Trustee may amend the Indenture without your consent:
  - to cure ambiguities;
  - to correct or supplement any defective or inconsistent provision;
  - to make any amendment required by any governmental agency; or
  - to make other changes determined not to be materially adverse to your best
    interest (as determined by the Sponsors).

Investors holding 51% of the units may amend the Indenture. Every investor must
consent to any amendment that changes the 51% requirement. No amendment may
reduce your interest in the Fund without your written consent.

The Trustee may resign by notifying the Sponsors. The Sponsors may remove the
Trustee without your consent if:

                                       13
<PAGE>
  - it fails to perform its duties and the Sponsors determine that its
    replacement is in your best interest; or
  - it becomes incapable of acting or bankrupt or its affairs are taken over by
    public authorities.

Investors holding 51% of the units may remove the Trustee. The Evaluator may
resign or be removed by the Sponsors and the Trustee without the consent of
investors. The resignation or removal of either becomes effective when a
successor accepts appointment. The Sponsors will try to appoint a successor
promptly; however, if no successor has accepted within 30 days after notice of
resignation, the resigning Trustee or Evaluator may petition a court to appoint
a successor.

Any Sponsor may resign as long as one Sponsor with a net worth of $2 million
remains and agrees to the resignation. The remaining Sponsors and the Trustee
may appoint a replacement. If there is only one Sponsor and it fails to perform
its duties or becomes bankrupt the Trustee may:
  - remove it and appoint a replacement Sponsor;
  - liquidate the Fund; or
  - continue to act as Trustee without a Sponsor.

Merrill Lynch, Pierce, Fenner & Smith Incorporated acts as agent for the
Sponsors.

The Trust Indenture contains customary provisions limiting the liability of the
Trustee, the Sponsors and the Evaluator.
LEGAL OPINION

Davis Polk & Wardwell, 450 Lexington Avenue, New York, New York 10017, as
special counsel for the Sponsors, has given an opinion that the units are
validly issued.

AUDITORS

Deloitte & Touche LLP, 2 World Financial Center, New York, New York 10281,
independent accountants, audited the Statement of Condition included in this
prospectus.

SPONSORS

The Sponsors and their underwriting percentages are:
MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED (a wholly-owned subsidiary of
Merrill Lynch & Co., Inc.)

P.O. Box 9051,
Princeton, NJ 08543-9051                                                  65.00%


SALOMON SMITH BARNEY INC.
(an indirectly wholly-owned subsidiary of
Citigroup Inc.)
388 Greenwich Street--23rd Floor,
New York, NY 10013                                                        10.00%


DEAN WITTER REYNOLDS INC. (a principal operating subsidiary of Morgan Stanley
Dean Witter & Co.)
Two World Trade Center--59th Floor,
New York, NY 10048                                                         5.00%
PAINEWEBBER INCORPORATED (a wholly-owned subsidiary of PaineWebber Group Inc.)
1285 Avenue of the Americas,
New York, NY 10019                                                        20.00%


                                                                         100.00%

Each Sponsor is a Delaware corporation and it, or its predecessor, has acted as
sponsor to many unit investment trusts. As a registered

                                       14
<PAGE>
broker-dealer each Sponsor buys and sells securities (including investment
company shares) for others (including investment companies) and participates as
an underwriter in various selling groups.

TRUSTEE


The Bank of New York, Unit Investment Trust Department, Box 974--Wall Street
Stateion, New York, New York 10268-0974 is the Trustee. It is supervised by the
Federal Deposit Insurance Corporation, the Board of Governors of the Federal
Reserve System and New York State banking authorities.


UNDERWRITERS' AND SPONSORS' PROFITS

Underwriters receive sales charges when they sell units. Sponsors also realize a
profit or loss on deposit of the bonds shown under Defined Portfolio. Any cash
made available by you to the Sponsors before the settlement date for those units
may be used in the Sponsors' businesses to the extent permitted by federal law
and may benefit the Sponsors.

A Sponsor or Underwriter may realize profits or sustain losses on bonds in the
Fund which were acquired from underwriting syndicates of which it was a member.
Approximately 10% of the bonds in the Fund were purchased from one or more of
the Sponsors.

During the initial offering period, the Sponsors also may realize profits or
sustain losses on units they hold due to fluctuations in the price per unit. In
maintaining a secondary market, the Sponsors will also realize profits or
sustain losses in the amount of any difference between the prices at which they
buy units and the prices at which they resell or redeem them.

PUBLIC DISTRIBUTION

During the initial offering period, units will be distributed to the public by
the Sponsors and dealers who are members of the National Association of
Securities Dealers, Inc. This period is 30 days or less if all units are sold.
The Sponsors may extend the initial period up to 120 days.

The Sponsors do not intend to qualify units for sale in any foreign countries.
This prospectus does not constitute an offer to sell units in any country where
units cannot lawfully be sold.

In the initial offering period, the concession to dealers will be $21 per 1,000
units. We may change the concession at any time. Dealers may resell units to
other dealers with a concession not in excess of the original concession to
dealers.

CODE OF ETHICS

Merrill Lynch, as agent for the Sponsors, has adopted a code of ethics requiring
preclearance and reporting of personal securities transactions by its employees
with access to information on portfolio transactions. The goal of the code is to
prevent fraud, deception or misconduct against the Fund and to provide
reasonable standards of conduct.

ADVERTISING AND SALES LITERATURE

Sales material may discuss developing a long-term financial plan, working with
your financial professional; the nature and risks of various investment
strategies and Defined Asset Funds that could help you toward your financial
goals and the importance of discipline; how securities are selected for these
funds, how the funds are created and operated, features such as convenience and
costs, and options available

                                       15
<PAGE>
for certain types of funds including automatic reinvestment, rollover, exchanges
and redemption. It may also summarize some similarities and differences with
mutual funds and discuss the philosophy of spending time in the market rather
than trying to time the market, including probabilities of negative returns over
various holding periods.

TAXES

The following summary describes some of the important income tax consequences of
holding units. It assumes that you are not a dealer, financial institution,
insurance company or other investor with special circumstances or subject to
special rules. You should consult your own tax adviser about your particular
circumstances.

At the date of issue of each bond, counsel for the issuer delivered an opinion
to the effect that interest on the bond is exempt from regular federal income
tax. However, interest may be subject to state and local taxes and may be taken
into account in determining your preference items for alternative minimum tax
purposes. Neither we nor our counsel have reviewed the issuance of the bonds,
related proceedings or the basis for the opinions of counsel for the issuers. We
cannot assure you that the issuer (or other users) have complied or will comply
with any requirements necessary for a bond to be tax-exempt. If any of the bonds
were determined not to be tax-exempt, you could be required to pay income tax
for current and prior years, and if the Fund were to sell the bond, it might
have to sell it at a substantial discount.

In the opinion of our counsel, under existing law:

GENERAL TREATMENT OF THE FUND AND YOUR INVESTMENT

The Fund will not be taxed as a corporation for federal income tax purposes, and
you will be considered to own directly your share of each bond in the Fund.

GAIN OR LOSS UPON DISPOSITION

When all or part of your share of a bond is disposed of (for example, when the
Fund sells, exchanges or redeems a bond or when you sell or exchange your
units), you will generally recognize capital gain or loss. Your gain, however,
will generally be ordinary income to the extent of any accrued "market
discount". Generally you will have market discount to the extent that your basis
in a bond when you purchase a unit is less than its stated redemption price at
maturity (or, if it is an original issue discount bond, the issue price
increased by original issue discount that has accrued on the bond before your
purchase). You should consult your tax adviser in this regard.

If your net long-term capital gains exceed your net short-term capital losses,
the excess may be subject to tax at a lower rate than ordinary income. Any
capital gain from the Fund will be long-term if you are considered to have held
your investment in each bond for more than one year and short-term otherwise.
Because the deductibility of capital losses is subject to limitations, you may
not be able to deduct all of your capital losses.

YOUR BASIS IN THE BONDS

Your aggregate basis in the bonds will be equal to the cost of your units,
including any sales charges and the organizational expenses

                                       16
<PAGE>
you pay, adjusted to reflect any accruals of "original issue discount,"
"acquisition premium" and "bond premium". You should consult your tax adviser in
this regard.

EXPENSES

If you are not a corporate investor, you will not be entitled to a deduction for
your share of fees and expenses of the Fund. Also, if you borrowed money in
order to purchase or carry your units, you will not be able to deduct the
interest on this borrowing for federal income tax purposes. The IRS may treat
your purchase of units as made with borrowed money even if the money is not
directly traceable to the purchase of units.

STATE AND LOCAL TAXES

Under the income tax laws of the State and City of New York, the Fund will not
be taxed as a corporation. If you are a New York taxpayer, your income from the
Fund will not be tax-exempt in New York except to the extent that the income is
earned on bonds that are tax-exempt for New York purposes. Depending on where
you live, your income from the Fund may be subject to state and local taxation.
You should consult your tax adviser in this regard.

SUPPLEMENTAL INFORMATION

You can receive at no cost supplemental information about the Fund by calling
the Trustee. The supplemental information includes more detailed risk disclosure
about the types of bonds that may be in the Fund's portfolio, general risk
disclosure concerning any insurance securing certain bonds, and general
information about the structure and operation of the Fund. The supplemental
information is also available from the SEC.

                                       17
<PAGE>
                       REPORT OF INDEPENDENT ACCOUNTANTS


The Sponsors, Trustee and Holders of Municipal Investment Trust Fund, Insured
Series--406, Defined Asset Funds (the "Fund"):



We have audited the accompanying statement of condition and the related defined
portfolio included in the prospectus of the Fund as of January 13, 2000. This
financial statement is the responsibility of the Trustee. Our responsibility is
to express an opinion on this financial statement based on our audit.


We conducted our audit in accordance with generally accepted auditing standards.
Those standards require that we plan and perform the audit to obtain reasonable
assurance about whether the financial statement is free of material
misstatement. An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statement. Our procedures included
confirmation of cash, securities and an irrevocable letter of credit deposited
for the purchase of securities, as described in the statement of condition, with
the Trustee. An audit also includes assessing the accounting principles used and
significant estimates made by the Trustee, as well as evaluating the overall
financial statement presentation. We believe that our audit provides a
reasonable basis for our opinion.


In our opinion, the financial statement referred to above presents fairly, in
all material respects, the financial position of the Fund as of January 13, 2000
in conformity with generally accepted accounting principles.



DELOITTE & TOUCHE LLP
NEW YORK, N.Y.
JANUARY 13, 2000


                 STATEMENT OF CONDITION AS OF JANUARY 13, 2000


TRUST PROPERTY


<TABLE>
<S>                                                        <C>
Investments--Bonds and Contracts to purchase Bonds(1)      $       9,274,135.10
Cash                                                                  20,000.00
Accrued interest to Initial Date of Deposit on underlying
  Bonds                                                               62,772.14
                                                           --------------------
        Total                                              $       9,356,907.24
                                                           ====================
LIABILITIES AND INTEREST OF HOLDERS
Liabilities: Advance by Trustee for accrued interest (2)   $          62,772.14
          Reimbursement of Sponsors for organization
expenses (3)                                                          20,000.00
                                                           --------------------
          Subtotal                                                    82,772.14
                                                           --------------------
Interest of Holders of 10,000,000 Units of fractional
  undivided interest outstanding:
          Cost to investors (3)(4)(5)                              9,386,135.10
          Organization expenses (3) and gross
underwriting commissions(4)                                         (112,000.00)
                                                           --------------------
          Subtotal                                                 9,274,135.10
                                                           --------------------
        Total                                              $       9,356,907.24
                                                           ====================
</TABLE>


- ------------


        (1) Aggregate cost to the Fund of the bonds listed under Defined
Portfolio is based upon the offer side evaluation determined by the Evaluator at
the evaluation time on the business day prior to the Initial Date of Deposit.
The contracts to purchase the bonds are collateralized by an irrevocable letter
of credit which has been issued by DBS Bank, New York Branch, in the amount of
$9,258,898.35 and deposited with the Trustee. The amount of the letter of credit
includes $9,189,400.25 for the purchase of $10,165,000.00 face amount of the
bonds, plus $69,498.10 for accrued interest.

        (2) Representing a special distribution to the Sponsors by the Trustee
of an amount equal to the accrued interest on the bonds.
        (3) A portion of the Unit Price consists of cash in an amount sufficient
to pay for costs incurred in establishing the Fund. These costs have been
estimated at $2.00 per 1,000 Units. A distribution will be made at the close of
the initial offering period to an account maintained by the Trustee from which
the organization expense obligation of the investors to the Sponsors will be
satisfied. If the actual organization costs exceed the estimated amount shown
above, the Sponsors will pay for this excess amount.
        (4) Assumes the maximum up-front sales fee per 1,000 units of 1.00% of
the Unit Price. A deferred sales fee of $19.00 per 1,000 Units is payable over a
two-year period ($2.38 per 1,000 Units quarterly in the first year and $2.37 per
1,000 units quarterly in the second year). Distributions will be made to an
account maintained by the Trustee from which the deferred sales fee obligation
of the investors will be satisfied. If units are redeemed prior to the final
deferred sales charge deduction, the remaining portion of the deferred sales fee
applicable to such units will be transferred to the account on the redemption
date.
        (5) Aggregate Unit Price (exclusive of interest) computed on the basis
of the offer side evaluation of the underlying bonds as of the evaluation time
on the business day prior to the Initial Date of Deposit.

                                       18
<PAGE>
              Defined
            Asset Funds

- -SM-


<TABLE>
<S>                                      <C>
HAVE QUESTIONS ?                         MUNICIPAL INVESTMENT TRUST FUND
Request the most                         INSURED SERIES--406
recent free Information                  (A Unit Investment Trust)
Supplement that gives more               ---------------------------------------
details about the Fund,                  This Prospectus does not contain
by calling:                              complete information about the
The Bank of New York                     investment company filed with the
1-800-221-7771                           Securities and Exchange Commission in
                                         Washington, D.C. under the:
                                         - Securities Act of 1933 (file no.
                                         333-90157) and
                                         - Investment Company Act of 1940 (file
                                         no. 811-3044).
                                         TO OBTAIN COPIES AT PRESCRIBED RATES--
                                         WRITE: Public Reference Section of the
                                         Commission
                                         450 Fifth Street, N.W., Washington,
                                         D.C. 20549-6009
                                         CALL: 1-800-SEC-0330.
                                         VISIT: http://www.sec.gov.
                                         ---------------------------------------
                                         No person is authorized to give any
                                         information or representations about
                                         this Fund not contained in this
                                         Prospectus or the Information
                                         Supplement, and you should not rely on
                                         any other information.
                                         ---------------------------------------
                                         When units of this Fund are no longer
                                         available, this Prospectus may be used
                                         as a preliminary prospectus for a
                                         future series, but some of the
                                         information in this Prospectus will be
                                         changed for that series.
                                         UNITS OF ANY FUTURE SERIES MAY NOT BE
                                         SOLD NOR MAY OFFERS TO BUY BE ACCEPTED
                                         UNTIL THAT SERIES HAS BECOME EFFECTIVE
                                         WITH THE SECURITIES AND EXCHANGE
                                         COMMISSION. NO UNITS CAN BE SOLD IN ANY
                                         STATE WHERE A SALE WOULD BE ILLEGAL.
                                                                 100467RR--01/00
</TABLE>

<PAGE>
                                    PART II
             ADDITIONAL INFORMATION NOT INCLUDED IN THE PROSPECTUS

<TABLE>
<S>                                                                     <C>                   <C>
       A. The following information relating to the Depositors is incorporated by reference to the SEC filings
indicated and made a part of this Registration Statement.
</TABLE>

 I. Bonding arrangements of each of the Depositors are incorporated by reference
to Item A of Part II to the Registration Statement on Form S-6 under the
Securities Act of 1933 for Municipal Investment Trust Fund, Monthly Payment
Series--573 Defined Asset Funds (Reg. No. 333-08241).

 II. The date of organization of each of the Depositors is set forth in Item B
of Part II to the Registration Statement on Form S-6 under the Securities Act of
1933 for Municipal Investment Trust Fund, Monthly Payment Series--573 Defined
Asset Funds (Reg. No. 333-08241) and is herein incorporated by reference
thereto.

III. The Charter and By-Laws of each of the Depositors are incorporated herein
by reference to Exhibits 1.3 through 1.12 to the Registration Statement on Form
S-6 under the Securities Act of 1933 for Municipal Investment Trust Fund,
Monthly Payment Series--573 Defined Asset Funds (Reg. No. 333-08241).

IV. Information as to Officers and Directors of the Depositors has been filed
pursuant to Schedules A and D of Form BD under Rules 15b1-1 and 15b3-1 of the
Securities Exchange Act of 1934 and is incorporated by reference to the SEC
filings indicated and made a part of this Registration Statement:

<TABLE>
<S>                                                                     <C>                   <C>
          Merrill Lynch, Pierce, Fenner & Smith Incorporated..........         8-7221
          Salomon Smith Barney Inc. ..................................         8-8177
          PaineWebber Incorporated....................................        8-16267
          Dean Witter Reynolds Inc. ..................................        8-14172
</TABLE>

                          ----------------------------

    B. The Internal Revenue Service Employer Identification Numbers of the
Sponsors and Trustee are as follows:

<TABLE>
<S>                                                                     <C>                   <C>
          Merrill Lynch, Pierce, Fenner & Smith Incorporated..........       13-5674085
          Salomon Smith Barney Inc. ..................................       13-1912900
          PaineWebber Incorporated....................................       13-2638166
          Dean Witter Reynolds Inc. ..................................       94-0899825
          The Bank of New York, Trustee...............................       13-4941102
</TABLE>

                                  UNDERTAKING

The Sponsors undertake that they will not instruct the Trustee to accept from
(i) AMBAC Indemnity Corporation; Financial Guaranty Insurance Company, MBIA
Insurance Corporation or any other insurance company affiliated with any of the
Sponsors, in settlement of any claim, less than an amount sufficient to pay any
principal or interest (and, in the case of a taxability redemption, premium)
then due on any Security in accordance with the municipal bond guaranty
insurance policy attached to such Security or (ii) any affiliate of the Sponsors
who has any obligation with respect to any Security, less than the full amount
due pursuant to the obligation, unless such instructions have been approved by
the Securities and Exchange Commission pursuant to Rule 17d-1 under the
Investment Company Act of 1940.

                                      II-1
<PAGE>
                         SERIES OF DEFINED ASSET FUNDS
        DESIGNATED PURSUANT TO RULE 487 UNDER THE SECURITIES ACT OF 1933

<TABLE>
<CAPTION>
                                                                      SEC
SERIES NUMBER                                                     FILE NUMBER
- -------------                                                     -----------
<S>                                                           <C>
Defined Asset Funds Municipal Defined Fund..................       333-58397
</TABLE>

                       CONTENTS OF REGISTRATION STATEMENT

The Registration Statement on Form S-6 comprises the following papers and
documents:

    The facing sheet of Form S-6.

    The Cross-Reference Sheet (incorporated by reference to the Cross-Reference
Sheet to the Registration Statement of Defined Asset Funds Municipal Series,
1933 Act File No. 33-54565).

    The Prospectus.

    Additional Information not included in the Prospectus (Part II).

The following exhibits:

<TABLE>
     <S>     <C>
       1.1   -- Form of Trust Indenture (incorporated by reference to Exhibit 1.1 to
             the Registration Statement of Defined Asset Funds Municipal Defined Fund
               Series 2, 1933 Act File No. 333-62185).
             -- Form of Standard Terms and Conditions of Trust Effective October 21,
      1.1.1  1993 (incorporated by reference to Exhibit 1.1.1 to the Registration
               Statement of Municipal Investment Trust Fund, Multistate Series-48,
               1933 Act File No. 33-50247).
       1.2   -- Form of Master Agreement Among Underwriters (incorporated by
             reference to Exhibit 1.2 to the Registration Statement of The Corporate
               Income Fund, One Hundred Ninety-Fourth Monthly Payment Series, 1933
               Act File No. 2-90925).
       2.1   --Form of Certificate of Beneficial Interest (included in Exhibit
             1.1.1).
       3.1   -- Opinion of counsel as to the legality of the securities being issued
             including their consent to the use of their name under the headings "How
               The Fund Works--Legal Opinion" in the Prospectus.
       4.1   --Consent of the Evaluator.
       5.1   --Consent of independent accountants.
       9.1   -- Information Supplement (incorporated by reference to Exhibit 9.1 to
             Amendment No. 1 to the Registration Statement of Municipal Investment
               Trust Fund, Multistate Series--409, 1933 Act File No. 333-81777).
</TABLE>

                                      R-1
<PAGE>
                              DEFINED ASSET FUNDS
                        MUNICIPAL INVESTMENT TRUST FUND
                                   SIGNATURES

    The registrant hereby identifies the series number of Defined Asset Funds
listed on page R-1 for the purposes of the representations required by Rule 487
and represents the following:

    1) That the portfolio securities deposited in the series as to which this
       registration statement is being filed do not differ materially in type or
       quality from those deposited in such previous series;

    2) That, except to the extent necessary to identify the specific portfolio
       securities deposited in, and to provide essential information for, the
       series with respect to which this registration statement is being filed,
       this registration statement does not contain disclosures that differ in
       any material respect from those contained in the registration statements
       for such previous series as to which the effective date was determined by
       the Commission or the staff; and

    3) That it has complied with Rule 460 under the Securities Act of 1933.


    PURSUANT TO THE REQUIREMENTS OF THE SECURITIES ACT OF 1933, THE REGISTRANT
HAS DULY CAUSED THIS REGISTRATION STATEMENT OR AMENDMENT TO THE REGISTRATION
STATEMENT TO BE SIGNED ON ITS BEHALF BY THE UNDERSIGNED THEREUNTO DULY
AUTHORIZED IN THE CITY OF NEW YORK AND STATE OF NEW YORK ON THE 13TH DAY
JANUARY, 2000

 .


               SIGNATURES APPEAR ON PAGES R-3, R-4, R-5 AND R-6.


    A majority of the members of the Board of Directors of Merrill Lynch,
Pierce, Fenner & Smith Incorporated has signed this Registration Statement or
Amendment to the Registration Statement pursuant to Powers of Attorney
authorizing the person signing this Registration Statement or Amendment to the
Registration Statement to do so on behalf of such members.

    A majority of the members of the Board of Directors of Salomon Smith Barney
Inc. has signed this Registration Statement or Amendment to the Registration
Statement pursuant to Powers of Attorney authorizing the person signing this
Registration Statement or Amendment to the Registration Statement to do so on
behalf of such members.

    A majority of the members of the Executive Committee of the Board of
Directors of PaineWebber Incorporated has signed this Registration Statement or
Amendment to the Registration Statement pursuant to Powers of Attorney
authorizing the person signing this Registration Statement or Amendment to the
Registration Statement to do so on behalf of such members.

    A majority of the members of the Board of Directors of Dean Witter Reynolds
Inc. has signed this Registration Statement or Amendment to the Registration
Statement pursuant to Powers of Attorney authorizing the person signing this
Registration Statement or Amendment to the Registration Statement to do so on
behalf of such members.

                                      R-2
<PAGE>
               MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED
                                   DEPOSITOR

<TABLE>
<S>                                       <C>
By the following persons, who constitute  Powers of Attorney have been filed
  a majority of                             under
  the Board of Directors of Merrill         Form SE and the following 1933 Act
  Lynch, Pierce,                            File
  Fenner & Smith Incorporated:              Number: 333-70593
</TABLE>

     GEORGE A. SCHIEREN
     JOHN L. STEFFENS
     By J. DAVID MEGLEN
       (As authorized signatory for Merrill Lynch, Pierce,
       Fenner & Smith Incorporated and
       Attorney-in-fact for the persons listed above)

                                      R-3
<PAGE>
                           SALOMON SMITH BARNEY INC.
                                   DEPOSITOR

<TABLE>
<S>                                                           <C>
By the following persons, who constitute a majority of        Powers of Attorney
  the Board of Directors of Salomon Smith Barney Inc.:          have been filed
                                                                under the 1933 Act
                                                                File Numbers:
                                                                333-63417 and
                                                                333-63033
</TABLE>

     MICHAEL A. CARPENTER
     DERYCK C. MAUGHAN

     By GINA LEMON
       (As authorized signatory for
       Salomon Smith Barney Inc. and
       Attorney-in-fact for the persons listed above)

                                      R-4
<PAGE>
                            PAINEWEBBER INCORPORATED
                                   DEPOSITOR

<TABLE>
<S>                                       <C>
By the following persons, who constitute  Powers of Attorney have been filed
  the Board of Directors of PaineWebber     under
  Incorporated:                             the following 1933 Act File
                                            Number: 2-61279
</TABLE>

     MARGO N. ALEXANDER
     TERRY L. ATKINSON
     BRIAN M. BAREFOOT
     STEVEN P. BAUM
     MICHAEL CULP
     REGINA A. DOLAN
     JOSEPH J. GRANO, JR.
     EDWARD M. KERSCHNER
     JAMES P. MacGILVRAY
     DONALD B. MARRON
     ROBERT H. SILVER
     MARK B. SUTTON
     By ROBERT E. HOLLEY
       (As authorized signatory for
       PaineWebber Incorporated
       and Attorney-in-fact for the persons listed above)

                                      R-5
<PAGE>
                           DEAN WITTER REYNOLDS INC.
                                   DEPOSITOR

<TABLE>
<S>                                       <C>
By the following persons, who constitute  Powers of Attorney have been filed
  a majority of                             under Form SE and the following 1933
  the Board of Directors of Dean Witter     Act File Numbers: 33-17085,
  Reynolds Inc.:                            333-13039, 333-47553 and 333-89045
</TABLE>

     BRUCE F. ALONSO
     RICHARD M. DeMARTINI
     RAYMOND J. DROP
     JAMES F. HIGGINS
     JOHN J. MACK
     MITCHELL M. MERIN
     STEPHEN R. MILLER
     PHILIP J. PURCELL
     JOHN H. SCHAEFER
     THOMAS C. SCHNEIDER
     ALAN A. SCHRODER
     ROBERT G. SCOTT
     By MICHAEL D. BROWNE
       (As authorized signatory for
       Dean Witter Reynolds Inc.
       and Attorney-in-fact for the persons listed above)

                                      R-6

<PAGE>
                                                                     EXHIBIT 3.1
                             DAVIS POLK & WARDWELL
                              450 LEXINGTON AVENUE
                            NEW YORK, NEW YORK 10017
                                 (212) 450-4000


                                                                January 13, 2000


Municipal Investment Trust Fund

Insured Series--406

Defined Asset Funds

Merrill Lynch, Pierce, Fenner & Smith Incorporated
Salomon Smith Barney Inc.
PaineWebber Incorporated
Dean Witter Reynolds Inc.

c/o Merrill Lynch, Pierce, Fenner & Smith Incorporated
   Defined Asset Funds
   P.O. Box 9051
   Princeton, NJ 08543-9051

Dear Sirs:


    We have acted as special counsel for you, as sponsors (the Sponsors) of
Municipal Investment Trust Fund, Insured Series--406, Defined Asset Funds (the
"Fund"), in connection with the issuance of units of fractional undivided
interest in the Fund (the "Units") in accordance with the Trust Indenture
relating to the Fund (the "Indenture").


    We have examined and are familiar with originals or copies, certified or
otherwise identified to our satisfaction, of such documents and instruments as
we have deemed necessary or advisable for the purpose of this opinion.

    Based upon the foregoing, we are of the opinion that (i) the execution and
delivery of the Indenture and the issuance of the Units have been duly
authorized by the Sponsors and (ii) the Units, when duly issued and delivered by
the Sponsors and the Trustee in accordance with the Indenture, will be legally
issued, fully paid and non-assessable.

    We hereby consent to the use of this opinion as Exhibit 3.1 to the
Registration Statement relating to the Units filed under the Securities Act of
1933 and to the use of our name in such Registration Statement and in the
related prospectus under the heading "How the Fund Works--Legal Opinion".

                                          Very truly yours,

                                          DAVIS POLK & WARDWELL

<PAGE>
                                                                     EXHIBIT 4.1

KENNY INFORMATION SYSTEMS,
A Division of J. J. Kenny Co., Inc.
55 Water Street
45th Floor
New York, New York 10021
Telephone: 212/438-2000
Fax: 212/438-4448
Frank A. Ciccotto, Jr.
Vice President


                                                                January 13, 2000



<TABLE>
<S>                                       <C>
Merrill Lynch Pierce Fenner & Smith
Incorporated
Defined Asset Funds
P.O. Box 9051
Princeton, NJ 08543-9051
The Bank of New York
Unit Investment Trust Department
P.O. Box 974
Wall Street Station
New York, N.Y. 10268-0974
</TABLE>


Re: MUNICIPAL INVESTMENT TRUST FUND,

    INSURED SERIES--406

    DEFINED ASSET FUNDS

Gentlemen:


    We have examined the Registration Statement File No. 333-90157 for the
above-captioned fund. We hereby acknowledge that Kenny Information Systems, a
Division of J. J. Kenny Co., Inc. is currently acting as the evaluator for the
fund. We hereby consent to the use in the Registration Statement of the
reference to Kenny Information Systems, a Division of J. J. Kenny Co., Inc. as
evaluator.


    In addition, we hereby confirm that the ratings indicated in the
Registration Statement for the respective bonds comprising the trust portfolio
are the ratings indicated in our KENNYBASE database as of the date of the
Evaluation Report.

    You are hereby authorized to file a copy of this letter with the Securities
and Exchange Commission.

                                          Sincerely,

                                          FRANK A. CICCOTTO, JR.
                                          VICE PRESIDENT

<PAGE>
                                                                     EXHIBIT 5.1
                       CONSENT OF INDEPENDENT ACCOUNTANTS


The Sponsors and Trustee of Municipal Investment Trust Fund, Insured
Series--406, Defined Asset Funds:



We consent to the use in this Registration Statement No. 333-90157 of our report
dated January 13, 2000 relating to the Statement of Condition of Municipal
Investment Trust Fund, Insured Series--406, Defined Asset Funds, and to the
reference to us under the heading "How the Fund Works--Auditors" in the
Prospectus which is a part of this Registration Statement.



DELOITTE & TOUCHE LLP
New York, N.Y.
January 13, 2000



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