BOSTON LIFE SCIENCES INC /DE
10-Q, 1998-08-14
PHARMACEUTICAL PREPARATIONS
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<PAGE>
 
                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, DC  20549
                                   FORM  10-Q
                                        
(MARK ONE)

(X)  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES EXCHANGE
     ACT OF 1934


     For the quarterly period ended    JUNE 30, 1998
                                       -------------
     
                                       OR

(  )  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE SECURITIES
      EXCHANGE ACT OF 1934

      For the transition period from ____________________ to __________________

Commission File Number                    0-6533
                       --------------------------------------------------------

                           BOSTON LIFE SCIENCES, INC.
- -------------------------------------------------------------------------------
             (Exact name of registrant as specified in its charter)

          Delaware                                          87-0277826
- -------------------------------------------------------------------------------
(State or other jurisdiction of                           (IRS Employer
 incorporation or organization)                         Identification No.)

31 Newbury Street, Suite 300, Boston, Massachusetts          02116
- -------------------------------------------------------------------------------
   (Address of principal executive offices)                (Zip code)

                                 (617) 425-0200
- -------------------------------------------------------------------------------
              (Registrant's telephone number, including area code)

                                 Not Applicable
- -------------------------------------------------------------------------------
   (Former name, former address and former fiscal year, if changed since last
                                    report)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.

                   (X)    Yes                    (  )    No

As of August 4, 1998 there were 13,210,312 shares of Common Stock outstanding.
<PAGE>
 
                           BOSTON LIFE SCIENCES, INC.

                               INDEX TO FORM 10-Q
                                        

                                                            Page (s)
                                                            --------

Part I - Financial Information:

  Item 1 - Financial Statements (unaudited)
<TABLE>
<CAPTION>
 
<S>                                                             <C>
  Condensed Consolidated Balance Sheet as of                        1
  June 30, 1998 and December 31, 1997
 
  Condensed Consolidated Statement of Operations                    2
  for the three and six months ended June 30, 1998 and 1997,
  and for the period from inception (October 16, 1992) to
  June 30, 1998
 
  Condensed Consolidated Statement of Cash Flows                    3
  for the six months ended June 30, 1998 and 1997,
  and for the period from inception (October 16, 1992) to
  June 30, 1998
 
  Notes to Condensed Consolidated Financial Statements          4 - 5
 
  Item 2 - Management's Discussion and Analysis of              6 - 9
           Financial Condition and Results of Operations
 
 
Part II - Other Information
 
  Item 1 - Legal Proceedings                                       10
 
  Item 2 - Changes in Securities                                   10
 
  Item 3 - Defaults Upon Senior Securities                         10
 
  Item 4 - Submission of Matters to a Vote of                      10
           Security Holders
 
  item 5 - Other Information                                       11
 
  item 6 - Exhibits and Reports on Form 8-K                        11
 
Signature (s)                                                      12
</TABLE>
<PAGE>
Part I -- Financial Information
Item 1 -- Financial Statements

                          Boston Life Sciences, Inc.
                       (A Development Stage Enterprise)

                          Consolidated Balance Sheet
                          --------------------------
                                  (Unaudited)
<TABLE>
<CAPTION>
                                                                    June 30, 1998            December 31, 1997    
                                                                 -------------------        -------------------
<S>                                                                 <C>                       <C> 
Assets                                                 
Current Assets:                                        
  Cash and cash equivalents                                             $ 617,094                $ 1,713,975
  Short-term investments                                               10,066,012                 12,338,496
  Prepaid sponsored research & development expenses                       150,000                    150,000
  Other current assets                                                    430,166                    508,208
                                                                      ------------              -------------
    Total current assets                                               11,263,272                 14,710,679
                                                       
Fixed assets, net                                                          60,541                     95,061
Technology acquired                                                     3,500,000                  3,500,000
Other assets                                                              273,229                    273,229
                                                                      ------------              -------------
    Total assets                                                     $ 15,097,042               $ 18,578,969
                                                                      ============              =============
                                                       
Liabilities and Stockholders' Equity                   
Current liabilities:                                   
  Accounts payable and accrued expenses                                 1,431,633                  1,991,804
                                                                      ------------              -------------
    Total current liabilities                                           1,431,633                  1,991,804
                                                                      ------------              -------------
                                                       
Stockholders' equity:                                  
  Series A Convertible Preferred stock, $.01 par value                        271                        284
    1,000,000 shares authorized                        
    27,145 shares outstanding on June 30, 1998 and     
    28,372 shares outstanding on December 31, 1997     
  Common stock, $0.01 par value;                                          130,750                    129,938
    25,000,000 shares authorized                       
    13,075,012 shares outstanding on June 30, 1998 and 
    12,993,838 shares outstanding on December 31, 1997 
  Additional paid-in-capital                                           50,120,045                 49,624,386
  Unrealized gains on investments                                          64,168                     99,029
  Deficit accumulated during development stage                        (36,649,825)               (33,266,472)
                                                                      ------------              -------------
    Total stockholders' equity                                         13,665,409                 16,587,165
                                                                      ------------              -------------
    Total liabilities and stockholders' equity                       $ 15,097,042               $ 18,578,969
                                                                      ============              =============
</TABLE> 


                See Notes to Consolidated Financial Statements
                                       
                                       1
<PAGE>
                          BOSTON LIFE SCIENCES, INC.
                       (A Development Stage Enterprise)

                     Consolidated Statement of Operations
                     ------------------------------------
                                  (Unaudited)

<TABLE>
<CAPTION>
                                                                                                           
                                                  Three Months Ended              Six Months Ended            From inception 
                                                       June 30,                       June 30,             (October 16, 1992)
                                            ----------------------------    -----------------------------      to June 30,    
                                                 1998           1997             1998          1997               1998
                                            --------------  ------------    -------------- --------------  ------------------
<S>                                         <C>             <C>               <C>           <C>             <C> 
Revenues                                             $ 0       $ 33,060              $ 0      $ 83,060       $    700,000
                                                                                                         
Operating Expenses
                                                                                       
Research and development expenses               1,127,708      1,355,762        2,245,352     2,329,754        14,142,465

Licensing fees                                          0              0           55,000             0           708,683

THERAFECTIN(R) related expenses                   133,782        629,087          260,782     1,180,132         3,997,613

General and administrative expenses               667,767        479,580        1,267,078       996,580         9,435,039

Purchased research and development in-proces            0              0                0             0        10,421,544
                                              -----------    -----------      -----------   -----------       ------------

        Loss from operations                  (1,929,257)    (2,431,369)      (3,828,212)   (4,423,406)       (38,005,344)

Net interest income                               193,809        283,233          444,859       610,382         1,355,519
                                              -----------    -----------      -----------   -----------       ------------
        Net loss                              $(1,735,448)   $(2,148,136)     $(3,383,353)  $(3,813,024)      $(36,649,825)
                                              ===========    ===========      ===========   ===========       ============
                                                                                                         
                                                                                                         
        Basic and diluted net 
          loss per common share                   $ (0.13)       $ (0.17)         $ (0.26)      $ (0.32) 
                                              ===========    ===========      ===========   ===========       
                                                                                                         
                                                                                                         
        Weighted average shares outstanding    13,050,970     12,454,621       13,031,926    12,037,923  
                                              ===========    ===========      ===========   ===========       

</TABLE>

                See notes to consolidated financial statements

                                       2
<PAGE>
                          BOSTON LIFE SCIENCES, INC.
                       (A Development Stage Enterprise)

                     Consolidated Statement of Operations
                     ------------------------------------
                                  (Unaudited)

<TABLE>
<CAPTION>
                                                                                                            Period from      
                                                                                                          inception(October
                                                                            Six months ended               16,1992)through   
                                                                        1998                1997            June 30, 1998
                                                                 ------------------  ------------------  ------------------
CASH FLOWS FROM OPERATING ACTIVITIES:
<S>                                                               <C>                  <C>                <C> 
Net loss                                                              $(3,383,353)        $(3,813,024)     $ (36,649,825)
Adjustments to reconcile net loss to net cash                                                           
    used for operating activities:                                                                      
    Purchased research and development in-process                               0                   0          10,421,544
    Compensation charge related to options and warrants granted           359,000             185,144           1,233,540
    Amortization and depreciation                                          40,000              40,000           1,395,583
    Loss on disposal of fixed assets                                            0                   0              15,589
    Changes in assets and liabilities:                                                              
     Prepaid sponsored research & development expenses                          0             391,000            (150,000)
     Other current assets                                                  78,042             330,587              65,362
     Accounts payable and accrued expenses                               (560,171)           (467,066)            483,968
     Deferred revenue                                                           0             (83,060)                  0
                                                                       -----------        ------------        ------------
     Net cash used for operating activities                            (3,466,482)         (3,416,419)        (23,184,239)
                                                                       -----------        ------------        ------------
                                                                                                        
CASH FLOWS FROM INVESTING ACTIVITIES:
 Net cash provided by acquisition of Greenwich Pharmaceuticals                  0                   0           1,758,037
 Increase in fixed assets                                                  (5,480)            (23,376)           (262,181)
 Proceeds from sale of fixed assets                                             0                   0               9,800
 Increase in other assets                                                       0                   0            (273,229)
 Short term investments:                                                                                 
    Purchases                                                          (6,290,019)         (5,983,119)        (37,847,973)
    Sales and maturities                                                8,527,642           5,501,343          27,846,129
                                                                       -----------        ------------        ------------
     Net cash provided by (used in) investing activities                2,232,143            (505,152)         (8,769,417)
                                                                       -----------        ------------        ------------
                                                                                                        
CASH FLOWS FROM FINANCING ACTIVITIES:
 Proceeds from issuance of common stock                                   137,458             128,836          13,147,203
 Proceeds from issuance of convertible preferred stock                          0                   0          20,872,170
 Proceeds from issuance of notes payable                                        0                   0           2,585,000
 Proceeds from issuance of convertible debt                                     0                   0           1,000,000
 Principal payments of notes payable                                            0             (57,286)         (2,796,467)
 Payment of note issuance costs                                                 0                   0            (399,702)
 Payment of stock issuance and merger transaction costs                         0                   0          (1,837,454)
                                                                       -----------        ------------        ------------
     Net cash provided by financing activities                            137,458              71,550          32,570,750
                                                                       -----------        ------------        ------------
                                                                                                        
Net increase (decrease) in cash and cash equivalents                   (1,096,881)         (3,850,021)            617,094
Cash and cash equivalents at beginning of period                        1,713,975           8,580,206                   0
                                                                       -----------        ------------        ------------
Cash and cash equivalents at end of period                              $ 617,094         $ 4,730,185           $ 617,094
                                                                       ===========        ============        ============

</TABLE>
                See notes to consolidated financial statements

                                       3

<PAGE>
 
                           BOSTON LIFE SCIENCES, INC.
                        (a development stage enterprise)

              Notes to Unaudited Consolidated Financial Statements
                                (June 30, 1998)


1. BASIS OF PRESENTATION

   The accompanying unaudited condensed consolidated financial statements have
   been prepared in accordance with generally accepted accounting principles for
   interim financial information and pursuant to the rules and regulations of
   the Securities and Exchange Commission. Accordingly, these financial
   statements do not include all of the information and footnotes required by
   generally accepted accounting principles for complete financial statements.

   The interim unaudited consolidated financial statements contained herein
   include, in management's opinion, all adjustments (consisting of normal
   recurring adjustments) necessary for a fair presentation of the financial
   position, results of operations, and cash flows for the periods presented.
   The results of operations for the interim period shown on this report are not
   necessarily indicative of results for a full year. These financial statements
   should be read in conjunction with the Company's consolidated financial
   statements and notes for the year ended December 31, 1997, appearing in the
   Company's Annual Report on Form 10-K for such year.


2. NET LOSS PER SHARE

   Net loss per share has been calculated by dividing net loss by the weighted
   average number of common shares outstanding during the period. All common
   stock equivalents have been excluded from the calculation of weighted average
   common shares outstanding since their inclusion would be anti-dilutive.


3. SUPPLEMENTAL DISCLOSURE OF NON-CASH INVESTING AND FINANCING ACTIVITIES

   During the six months ended June 30, 1998, the Company issued 21,519 shares
   of common stock resulting from the conversion of 1,227 shares of preferred
   stock. During the six months ended June 30, 1997, the Company issued
   1,394,020 shares of common stock resulting from the conversion of 79,487
   shares of preferred stock.

                                       4
<PAGE>
 
                           Boston Life Sciences, Inc.
                        (a development stage enterprise)

              Notes to Unaudited Consolidated Financial Statements
                                (June 30, 1998)


4. COMPREHENSIVE NET LOSS

   The Company adopted FASB Statement No. 130, "Reporting Comprehensive Income",
   in the first quarter of 1998.  This statement establishes standards for the
   reporting and display of comprehensive income or loss and its components in
   the financial statements.  Comprehensive net loss for the six months ended
   June 30, 1998 and 1997, was as follows:
 
<TABLE>
<CAPTION>
                                                      1998                   1997
      <S>                                      <C>                    <C>
      Net loss                                     $(3,383,353)           $(3,813,024)
      Unrealized loss on investments              (     34,861)           (    33,905)
                                                   -----------            -----------
      Comprehensive net loss                       $(3,418,214)           $(3,846,929)
                                                   ===========            ===========
</TABLE>
                                                                                

5. INVESTMENTS

   At June 30, 1998, the fair value of short-term investments exceeded their
   cost basis by approximately $64,000.  These investments, which are classified
   as available-for-sale, are reported at fair value, with the unrealized gain
   excluded from the statement of operations and reported as a separate
   component of stockholders' equity.

                                       5
<PAGE>
 
ITEM 2.               MANAGEMENT'S DISCUSSION AND ANALYSIS
                OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
                                (June 30, 1998)


     This Quarterly Report on Form 10-Q contains forward-looking statements.
Specifically, any statements contained herein that are not statements of
historical fact may be deemed to be forward-looking statements.  Without
limiting the foregoing, the words "believes," "anticipates," "plans," "expects,"
and similar expressions are intended to identify forward-looking statements.
There are a number of meaningful factors that could cause the Company's actual
results to differ materially from those indicated by any such forward-looking
statements.  These factors include, without limitation, the duration and results
of clinical trials and their effect on the FDA regulatory process, uncertainties
regarding receipt of approvals for any possible products and any commercial
acceptance of such products, possible difficulties with obtaining necessary
patent protection, and uncertainties regarding the outcome of any of the
Company's collaborations or alliances with third parties.  Other factors include
those set forth under the caption "Forward-Looking Statements" in the Company's
Annual Report on Form 10-K for the year ended December 31, 1997 and the
documents referred to under such caption.

RESULTS OF OPERATIONS

 Overview
 
     The Company is a biotechnology company engaged in the research and
development of novel therapeutic and diagnostic products to treat chronic
debilitating diseases such as cancer, central nervous system disorders and
autoimmune diseases.  The Company expects that its research and development
costs will increase as the Company attempts to gain regulatory approval for
commercial introduction of its proposed products.  At June 30, 1998, the Company
is considered a "development stage enterprise" as defined in Statement of
Financial Accounting Standards No. 7.


 Three Months Ended June 30, 1998 and 1997

     The Company's net loss was $1,735,448 during the three months ended June
30, 1998 as compared with $2,148,136 during the three months ended June 30,
1997.  Net loss per common share equaled $.13 per share for the 1998 period as
compared to $.17 per share for the 1997 period.  The lower net loss in the 1998
period was primarily due to lower THERAFECTIN/(R)/ related expenses, and to a
lesser degree, a reduction in research and development expenses.  These
decreases were partially offset by higher general and administrative expenses
and a reduction in net interest income.

     Revenue was zero during the three months ended June 30, 1998 as compared
with $33,060 during the comparable 1997 period. Revenue for the 1997 period was
attributable to a research and development agreement (the "Agreement") entered
into with Zeneca Pharmaceuticals, Ltd. ("Zeneca Pharmaceuticals") in 1995. Under
the terms of the Agreement (which originally would have expired in June 1997),
Zeneca provided funds for a two-year period to support the research and
development of certain technology. In addition to providing funding, Zeneca, at
its own expense, undertook the screening of its molecule collection, in order to
generate potential inhibitors of the Company's transcription factor. Zeneca
requested, and was granted, an extension, until January 1, 1998, to continue the
screening of its molecule collection before deciding if it would exercise its
product development rights. Following the refusal by the Company to grant Zeneca
a further extension, Zeneca informed the Company that it will not continue
product development. The Company believes that this technology has substantial
value and plans to continue to pursue alternative potential joint venture and
collaborative opportunities in this sector.

                                       6
<PAGE>
 
     Research and development expenses were $1,127,708 during the three months
ended June 30, 1998 as compared with $1,355,762 during the three months ended
June 30, 1997. The decrease was primarily attributable to lower expenditures for
two of the technologies currently under pre-clinical development, partially
offset by increased expenditures related to the preparation for and initiation
of clinical trials for Altropane. The majority of the Company's research and
development expenses were sponsored research obligations paid to Harvard
University and its affiliated hospitals. The Company expects to incur total
research and development costs between $4 million and $5 million during 1998.

     Licensing fees were zero during both the three months ended June 30, 1998
and during the three months ended June 30, 1997.  The Company did not execute
any new licensing agreements during either period or incur any obligations under
its existing licensing agreements. In addition to an initial licensing fee
payment, the Company is obligated to pay additional amounts upon the attainment
of development milestones, as defined in each respective licensing agreement, as
well as royalties upon the sales of any resulting products. The Company expects
to pay future licensing fees, the timing and amounts of  which will depend upon
the terms of agreements which may be executed for technologies currently being
developed or which may be developed in the future.  There can be no assurance
regarding the likelihood or materiality of any such future licensing agreements.

     THERAFECTIN(R) related expenses were $133,782 during the three months ended
June 30, 1998 as compared with $629,087 during the three months ended June 30,
1997. This decrease reflects differences in the status of the Phase III clinical
trial for Therafectin during each respective period. The Phase III trial, which
began in March 1996, was completed in August 1997. Expenses during the 1998
period primarily related to patients enrolled in the extension phase of the
trial in which fewer patients were enrolled, and per-patient clinical costs were
lower. The Company filed, in June 1998, an amendment to its previously filed New
Drug Application ("NDA") with the Food and Drug Administration ("FDA") seeking
marketing approval for Therafectin. There can be no assurance, however, that
such approval will be obtained by the Company. If the Company is ultimately
unsuccessful in obtaining regulatory approval for Therafectin, the Company may
be required to write off all or some portion of the $3.5 million asset value
represented by the THERAFECTIN(R) technology acquired in the June 1995 merger
with Greenwich Pharmaceuticals, Inc. as reflected on the Company's balance
sheet.

     General and administrative expenses were $667,767 during the three months
ended June 30, 1998 as compared with $479,580 during the comparable 1997 period.
This increase was primarily due to  higher professional services costs and a
non-cash charge related to certain changes in the provisions of the Company's
stock option plans.

     Net interest income was $193,809 during the three months ended June 30,
1998 as compared with net interest income of $283,233 during the three months
ended June 30, 1997. The higher level of interest income recognized during the
1997 period primarily related to higher average short-term investment, cash and
cash equivalent balances.


 Six Months Ended June 30, 1998 and 1997

     The Company's net loss was $3,383,353 during the six months ended June 30,
1998 as compared with $3,813,024 during the six months ended June 30, 1997.  Net
loss per common share equaled $.26 per share for the 1998 period as compared to
$.32 per share for the 1997 period. The lower net loss in the 1998 period was
primarily due to lower THERAFECTIN/(R) / related expenses, and to a lesser
degree, a reduction in research and development expenses.  These expenses were
partially offset by higher general and administrative expenses and a reduction
in net interest income.

                                       7
<PAGE>
 
     Revenue was zero during the six months ended June 30, 1998 as compared with
$83,060 during the comparable 1997 period. Revenue for the 1997 period was
attributable to a research and development agreement (the "Agreement") entered
into with Zeneca Pharmaceuticals, Ltd. ("Zeneca Pharmaceuticals") in 1995. Under
the terms of the Agreement (which originally would have expired in June 1997)
Zeneca provided funds for a two-year period to support the research and
development of certain technology. In addition to providing funding, Zeneca, at
its own expense, undertook the screening of its molecule collection, in order to
generate potential inhibitors of the Company's transcription factor. Zeneca
requested, and was granted, an extension, until January 1, 1998, to continue the
screening of its molecule collection before deciding if it would exercise its
product development rights. Following the refusal by the Company to grant Zeneca
a further extension, Zeneca informed the Company that it will not continue
product development. The Company believes that this technology has substantial
value and plans to continue to pursue alternative potential joint ventures and
collaborative opportunities in this sector.

     Research and development expenses were $2,245,352 during the six months
ended June 30, 1998 as compared with $2,329,754 during the six months ended June
30, 1997. The decrease was primarily attributable to lower expenditures for two
of the technologies currently under pre-clinical development, partially offset
by increased expenditures related to the preparation for and initiation of
clinical trials for Altropane.  The majority of the Company's research and
development expenses were sponsored research obligations paid to Harvard
University and its affiliated hospitals.  The Company expects to incur research
and development costs between $4 million and $5 million during 1998.

     Licensing fees were $55,000 during the six months ended June 30, 1998 as
compared with zero during the six months ended June 30, 1997. During the 1998
period, the Company paid $15,000 to license one new technology as compared to no
new licensing agreements during the 1997 period.  In addition to an initial
licensing fee payment, the Company is obligated to pay additional amounts upon
the attainment of development milestones, as defined in each respective
licensing agreement, as well as royalties upon the sales of any resulting
products. During the 1998 period, the Company made a milestone payment of
$40,000 related to the development of one of its technologies.  The Company
expects to pay future licensing fees, the timing and amounts of which will
depend upon the progress attained in developing existing technologies and the
terms of agreements which may be executed for technologies currently being
developed or which may be developed in the future. There can be no assurance
regarding the likelihood or materiality of any such future licensing agreements.

     THERAFECTIN(R) related expenses were $260,782 during the six months ended
June 30, 1998 as compared with $1,180,132 during the six months ended June 30,
1997. This decrease reflects differences in the status of the Phase III clinical
trial for Therafectin during each respective period. The Phase III trial, which
began in March 1996, was completed in August 1997. Expenses during the 1998
period primarily related to patients enrolled in the extension phase of the
trial in which fewer patients were enrolled, and per-patient clinical costs were
lower. The Company filed, in June 1998, an amendment to its previously filed New
Drug Application ("NDA") with the Food and Drug Administration ("FDA") seeking
marketing approval for Therafectin. There can be no assurance, however, that
such approval will be obtained by the Company. If the Company is ultimately
unsuccessful in obtaining regulatory approval for Therafectin, the Company may
be required to write off all or some portion of the $3.5 million asset value
represented by the THERAFECTIN(R) technology acquired in the Merger with
Greenwich Pharmaceuticals, Inc. as reflected on the Company's balance sheet.

     General and administrative expenses were $1,267,078 during the six months
ended June 30, 1998 as compared with $996,580 during the comparable 1997 period.
This increase was primarily due to  higher professional services costs and a
non-cash charge related to certain changes in the provisions of the Company's
stock option plans.

                                       8
<PAGE>
 
     Net interest income was $444,859 during the six months ended June 30, 1998
as compared with net interest income of $610,382 during the six months ended
June 30, 1997. The higher level of interest income recognized during the 1997
period primarily related to higher average short-term investment, cash and cash
equivalent balances.

  YEAR 2000 COMPLIANCE

     The Company uses a significant number of computer software programs and 
operating systems in its internal operations, including applications used in  
product development, financial business systems and various administrative 
functions. To the extent that these software applications contain source code 
that is unable to appropriately interpret the upcoming calendar year "2000," 
some level of modifications or even possibly replacement of such source code or 
applications will be necessary. The Company is currently in the process of 
completing its identification of software applications that are not "Year 2000" 
compliant and expects to make appropriate responses to address any issue 
identified by the end of 1998. Given the information known at this time about 
the Company's systems, coupled with the Company's ongoing, normal 
course-of-business efforts to upgrade or replace business critical systems as 
necessary, it is currently not anticipated that these "Year 2000" costs will 
have any material adverse effect on the Company's business, financial condition 
or results of operation. However, the Company is still in the preliminary 
stages of analyzing its software applications and, to the extent they are not 
fully "Year 2000" compliant, there can be no assurance that the costs necessary 
to update software, or potential systems interruptions, would not have a 
material adverse effect on the Company's business, financial condition or 
results of operations. However, if the Company and third parties upon which it 
relies are unable to address this issue in a timely manner, it could result in a
material financial risk to the Company. In order to assure that this does not 
occur, the Company plans to devote all resources required to resolve any 
significant year 2000 issues in a timely manner.
 
  LIQUIDITY AND CAPITAL RESOURCES

     Since its inception, the Company has satisfied its working capital
requirements from the sale of the Company's securities through private
placements.  In January and February 1996, the Company raised approximately
$20.7 million of net proceeds by completing a private placement of units
consisting of (i) shares of its Series A Convertible Preferred Stock and (ii)
warrants to purchase shares of the Company's common stock.  In June 1996, the
Company raised approximately $5 million of net proceeds by completing a private
placement of 500,000 shares of common stock (See Notes 8 and 9 of Notes to the
Consolidated Financial Statements in the Company's Annual Report on Form 10-K
for the year ended December 31, 1997).  In the future, the Company's ability to
meet, and the level of, its working capital and capital requirements will depend
on numerous factors, including the progress of the Company's research and
development activities, the level of resources that the Company devotes to the
developmental, clinical, and regulatory aspects of its products, and the extent
to which the Company enters into collaborative relationships with pharmaceutical
and biotechnology companies.

  At June 30, 1998, the Company had available cash, cash equivalents and short
term investments of approximately $10.7 million and working capital of
approximately $9.8 million.  The Company believes that the level of financial
resources available at June 30, 1998 will provide sufficient working capital to
meet its anticipated expenditures for more than the next twelve months.  The
Company may raise additional capital in the future through collaboration
agreements with other pharmaceutical or biotechnology companies, debt financings
and equity offerings.  There can be no assurance, however, that the Company will
be successful in such efforts or that additional funds will be available on
acceptable terms, if at all.

                                       9
<PAGE>
 
                          PART II -- OTHER INFORMATION
                          ----------------------------


ITEM 1:  LEGAL PROCEEDINGS.
         ----------------- 
         
         None.
         
ITEM 2:  CHANGES IN SECURITIES.
         --------------------- 

         During the six months ended June 30, 1998, the Company issued 59,655
         shares of common stock related to the exercise of outstanding warrants
         and options for which the Company received consideration totaling
         $137,458.

ITEM 3:  DEFAULTS UPON SENIOR SECURITIES.
         ------------------------------- 

         None.

ITEM 4:  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.
         --------------------------------------------------- 

         The annual meeting of stockholders was held on June 12, 1998. the
         holders of more than a majority of the shares entitled to vote were
         represented at the meeting in person or by proxy, constituting a
         quorom. At the meeting, the following matters were voted upon by the
         stockholders, receiving the number of affirmative and witheld or
         negative ("withheld") votes set forth below each matter.

         1. Proposal to elect directors each to serve until the date of the 1999
            annual meeting of stockholders and until their successors are
            elected and qualified: 
<TABLE>
<CAPTION>
 
                                                     For       Withheld/Against 
                                                -------------  ----------------
                <S>                          <C>              <C>
                Colin B. Bier, Ph.D.              9,494,448        53,146   
                Edson D. de Castro                9,491,151        56,442
                Adrian Gerber                     9,494,274        53,319   
                S. David Hillson, Esq.            9,488,388        59,206     
                Marc E. Lanser, M.D.              9,491,173        56,420    
                Ira W. Lieberman, Ph.D.           9,491,772        55,822    
                E. Christopher Palmer             9,519,026        28,567    
</TABLE> 
 
         2. Proposal to approve and adopt the Company's 1998 Omnibus Stock 
            Option Plan:
 
                                                     For       Withheld/Against
                                                     ---       ----------------
                                                  9,351,378       196,216
 
         3. Proposal to approve the Amendment and Restatement of the Company's
            Amended and Restated 1990 Non-Employee Directors' Non-Qualified
            Stock Option Plan:

                                                     For       Withheld/Against
                                                     ---       ----------------
                                                  9,175,200       372,393

                                       10
<PAGE>
 
ITEM 5:  OTHER INFORMATION.
         -----------------

         (a) Exhibits.

             None.


ITEM 6:  EXHIBITS AND REPORTS ON FORM 8-K.
         -------------------------------- 

         (a) Exhibits included with this filing:
 
             27 Financial Data Schedule

         (b) Reports on Form 8-K: The Registrant filed the following reports on
             Form 8-K during the quarter ended June 30, 1998 and through 
             August 8, 1998.
 
               Date of Report                      Item Reported
               --------------                      -------------
 
         1     Form 8-K filed April 30, 1998            5,7
 
         2     Form 8-K filed May 7, 1998               5,7
 
         3     Form 8-K filed May 8, 1998               5,7
 
         4     Form 8-K filed July 1, 1998              5,7
 
 

                                       11
<PAGE>
 
                                   SIGNATURE
                                   ---------


     Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                      BOSTON LIFE SCIENCES, INC.
                                      --------------------------
                                         (Registrant)


DATE: August 12, 1998                 /s/ S. David Hillson
                                      -----------------------------
                                      S. David Hillson
                                      President and Chief Executive Officer
                                      (Principal Executive Officer)
 
                                      /S/ Joseph Hernon
                                      -----------------------------
                                      Joseph Hernon
                                      Chief Financial Officer
                                      (Principal Financial and Accounting
                                        Officer)

                                       12

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM FINANCIAL
STATEMENTS AS REPORTED ON FORM 10-Q AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS
</LEGEND>
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                          DEC-31-1998
<PERIOD-START>                             JAN-01-1998
<PERIOD-END>                               JUN-3O-1998
<CASH>                                         617,094
<SECURITIES>                                10,066,012
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                            11,263,272
<PP&E>                                         264,024
<DEPRECIATION>                               (203,483)
<TOTAL-ASSETS>                             (15,097,042)
<CURRENT-LIABILITIES>                        1,431,633
<BONDS>                                              0
                                0
                                        271
<COMMON>                                       130,750
<OTHER-SE>                                  13,534,388
<TOTAL-LIABILITY-AND-EQUITY>                16,523,773
<SALES>                                              0
<TOTAL-REVENUES>                                     0
<CGS>                                                0
<TOTAL-COSTS>                                3,828,212
<OTHER-EXPENSES>                             (444,859)
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                   0
<INCOME-PRETAX>                            (3,383,353)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                        (3,383,353)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                               (3,383,353)
<EPS-PRIMARY>                                   (0.26)
<EPS-DILUTED>                                   (0.26)
        

</TABLE>


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