DEUTSCHE BANK AG\
SC 13G, 1998-10-06
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                   -----------------------------------------

                                  SCHEDULE 13G

                   Under the Securities Exchange Act of 1934



                                  Qiagen N.V.
                   -----------------------------------------

                                (Name of issuer)




                                Ordinary Shares
                   -----------------------------------------

                         (Title of class of securities)



                                   000N724821
                   -----------------------------------------

                                 (CUSIP number)



            (Date of Event which requires filing of this Statement)

          Check the appropriate box to designate the rule pursuant to
                        which this schedule is filed:

                                ()  Rule 13d-1 (b)
                                (x) Rule 13d-1 (c)
                                ()  Rule 13d-1 (d)

<PAGE>

- ---------------------------------
      CUSIP No. 000N724821                     13G
- ---------------------------------



- -------- -----------------------------------------------------------------------
1        NAME OF REPORTING PERSON
         S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

         Deutsche Bank A.G.
- -------- -----------------------------------------------------------------------
2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP              (a) ()
                                                                       (b) ()
- -------- -----------------------------------------------------------------------
3        SEC USE ONLY

- -------- -----------------------------------------------------------------------
4        CITIZENSHIP OR PLACE OF ORGANIZATION

         Federal Republic of Germany
- ---------------------------- ------ --------------------------------------------
NUMBER OF SHARES             5      SOLE VOTING POWER
                                    411,016
                             ------ --------------------------------------------
BENEFICIALLY OWNED BY               SHARED VOTING POWER
                             6      1,104,414
                             ------ --------------------------------------------
EACH REPORTING                      SOLE DISPOSITIVE POWER
                             7      524,466
                             ------ --------------------------------------------
PERSON WITH                         SHARED DISPOSITIVE POWER
                             8      1,104,414
- -------- -----------------------------------------------------------------------
 9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         1,628,880
- -------- -----------------------------------------------------------------------
10       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
         CERTAIN SHARES                                                     ()
- -------- -----------------------------------------------------------------------
11       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

         10.0%
- -------- -----------------------------------------------------------------------
12       TYPE OF REPORTING PERSON

         HC, BK, CO
- -------- -----------------------------------------------------------------------
<PAGE>


Item 1(a).        Name of Issuer:

                  Qiagen N.V. (the "Issuer")

Item 1(b).        Address of Issuer's Principal Executive Offices:

                  The  address  of  the  Issuer's  principal   executive  office
Johannes Vermersplain 9-1, Amsterdam, 1071 DV, Netherlands.

Item 2(a).        Name of Person Filing:

                  This  statement  is filed on behalf of  Deutsche  Bank AG (the
"Reporting Person").

Item 2(b).        Address of Principal Business Office or, if none, Residence:

                  The  principal  place of business of the  Reporting  Person is
Taunusanlage 12, D-60325, Frankfurt am Main, Federal Republic of Germany.

Item 2(c).        Citizenship:

                  The  citizenship  of the Reporting  Person is set forth on the
cover page.

Item 2(d).        Title of Class of Securities:

                  The title of the securities is ordinary  shares (the "Ordinary
Shares").

Item 2(e).        CUSIP Number:

                  The CUSIP  number of the  Ordinary  Shares is set forth on the
cover page.

Item 3.          If this statement is filed pursuant to Rules 13d-1(b), or 13d-2
                 (b) or (c), check whether the person filing is a:

                 (a)()  Broker or dealer registered under section 15 of the Act;

                 (b)() Bank as defined in section 3(a)(6) of the Act;

                 (c)() Insurance Company as defined in section 3(a)(19) of the
                       Act;

                 (d)() Investment  Company  registered  under section 8 of the
                       Investment Company Act of 1940;

                 (e)() An  investment  adviser in  accordance  with Rule 13d-1
                       (b)(1)(ii)(E);

                 (f)() An  employee  benefit  plan,  or  endowment  fund  in
                       accordance with Rule 13d-1 (b)(1)(ii)(F);

                 (g)() A parent holding company or control person in accordance
                       with Rule 13d-1 (b)(1)(ii)(G);

                 (h) ()A savings association as defined in section 3(b) of the
                       Federal Deposit Insurance Act;

                 (i) () A  church  plan  that  is  excluded  from  the
                        definition of an  investment  company under section
                        3(c)(14) of the Investment Company Act of 1940;

                 (j) () Group, in accordance with Rule 13d-1 (b)(1)(ii)(J).

                  If this statement is filed pursuant to Rule 13d-1 (c), check 
this box.   (x)

Item 4.  Ownership.

         (a)      Amount beneficially owned:

                           The Reporting  Person owns the amount of the Ordinary
                  Shares as set forth on the cover page.

                  (b)      Percent of class:

                           The  Reporting  Person  owns  the  percentage  of the
                  Ordinary Shares as set forth on the cover page.

                  (c) Number of shares as to which such person has:

                           (i)      sole power to vote or to direct the vote:

                                    The  Reporting  Person has the sole power to
                           vote or direct the vote of the Ordinary Shares as set
                           forth on the cover page.

                           (ii) shared power to vote or to direct the vote:

                                    The Reporting Person has the shared power to
                           vote or direct the vote of the Ordinary Shares as set
                           forth on the cover page.

                           (iii)   sole power to dispose or to direct the
                                   disposition of:

                                    The  Reporting  Person has the sole power to
                           dispose or direct  the  disposition  of the  Ordinary
                           Shares as set forth on the cover page.

                           (iv)    shared  power  to dispose  or  to direct the
                                   disposition of:

                                   The Reporting Person has the shared power to
                           dispose or direct  the  disposition  of the  Ordinary
                           Shares as set forth on the cover page.

Item 5.  Ownership of Five Percent or Less of a Class.

         Not applicable.

Item 6.  Ownership of More than Five Percent on Behalf of Another Person.

         Investment management clients of the subsidiaries of the Reporting 
Person listed in Item 7 have the ultimate right to any dividends from Ordinary
Shares and the proceeds from the sale of Ordinary Shares.

Item 7.  Identification and Classification of the Subsidiary Which Acquired the
         Security Being Reported on by the Parent Holding Company.

         The following are  subsidiaries of the Reporting  Person which
hold Ordinary Shares included in the figures on the cover pages: Morgan Grenfell
Investment  Services  Limited,  Morgan  Grenfell  International  Fund Management
Limited,   Deutsche   Gesellschaft  fur  Wertpapiersparen   mbH,  Deutsche  Fund
Management  Inc.,  Deutsche  Vermogensbildungsgesellschaft  mbH,  Deutsche  Bank
Investment Management S.A., DWS (Austria)  Investment-Gesellschaft mbH, Deutsche
Bank  Fonds  S.A.,   Finanza  &  Futuro  S.p.A.,   Deutsche   Gesellschaft   fur
Fondsverwaltung mbH and Deutsche Bank Securities Inc.

Item 8.  Identification and Classification of Members of the Group.

         Not applicable.

Item 9.  Notice of Dissolution of Group.

         Not applicable.

Item 10. Certification.

         By signing  below I certify  that, to the best of my knowledge
and belief, the securities  referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing  the control of
the  issuer  of the  securities  and  were  not  acquired  and are  not  held in
connection  with or as a participant in any  transaction  having that purpose or
effect.



<PAGE>


                                   SIGNATURE

         After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  statement is true,
complete and correct.

Dated:  October 6, 1998



                                                   DEUTSCHE BANK AG



                                                   By:/s/ Dr. Dieter Eisele
                                                      ---------------------- 
                                                       Name:   Dr. Dieter Eisele
                                                       Title:  Group Head of 
                                                               Compliance



                                                   By:/s/ Rondal Eric Powell
                                                      ----------------------
                                                      Name:   Rondal Eric Powell
                                                      Title:  Vice President



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