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<PAGE> 1
Filed Pursuant to
Rule 424(b)(3) and (c)
File No. 333-50505
PROSPECTUS SUPPLEMENT NO. 10 DATED APRIL 6, 1999
TO PROSPECTUS DATED MAY 4, 1998
AVIRON
$100,000,000
5 3/4% Convertible Subordinated Notes due 2005
and
Shares of Common Stock Issuable Upon Conversion thereof
This Prospectus Supplement should be read in conjunction with the
Prospectus dated May 4, 1998 (the "Prospectus"). The table on pages 45 and 46 of
the Prospectus setting forth information concerning the Selling Securityholders
is superseded by the following table:
SELLING SECURITYHOLDERS
The following table sets forth the names of the Selling Securityholders,
the number of shares of Common Stock owned by each of them as of the date of
this supplement and the principal amount of Notes and number of Conversion
Shares which may be offered pursuant to this Prospectus. The information is
based upon information provided by or on behalf of the Selling Securityholders.
The Selling Securityholders may offer all, some or none of their Notes or
Conversion Shares.
<TABLE>
<CAPTION>
PRINCIPAL
AMOUNT OF
NOTES OWNED PRINCIPAL COMMON STOCK COMMON STOCK
PRIOR TO AMOUNT OF NOTES OWNED PRIOR TO OFFERED
NAME OFFERING(1) OFFERED HEREBY OFFERING(1)(2) HEREBY
---- ---------- ---------- ---------- ----------
<S> <C> <C> <C> <C>
AAM/Zazove Institutional
Income Fund, L.P. $ 0 $ 0 0 0
Alexandra Global Investment
Fund I, Inc. 2,000,000 2,000,000 70,716 0
Amoco Corporation Master Trust 0 0 0 0
Argent Classic Convertible
Arbitrage Fund L.P. 0 0 0 0
Argent Classic Convertible
Arbitrage Fund (Bermuda) L.P. 0 0 0 0
Bakers Local 433 Pension Trust 40,000 40,000 0 0
BancAmerica Robertson Stephens 195,000 195,000 0 0
BNP Arbitrage SNC 2,550,000 2,550,000 0 0
BT Holdings (New York), Inc. 1,000,000 1,000,000 0 0
</TABLE>
1.
<PAGE> 2
<TABLE>
<CAPTION>
PRINCIPAL
AMOUNT OF
NOTES OWNED PRINCIPAL COMMON STOCK COMMON STOCK
PRIOR TO AMOUNT OF NOTES OWNED PRIOR TO OFFERED
NAME OFFERING(1) OFFERED HEREBY OFFERING(1)(2) HEREBY
---- ---------- ---------- ---------- ----------
<S> <C> <C> <C> <C>
Chrysler Corporation Master
Retirement Trust 1,370,000 1,370,000 0 0
CIBC Oppenheimer 0 0 0 0
Contrary Fund LLC 0 0 0 0
Declaration of Trust for the
Defined Benefit Plans of ICI
American Holdings Inc. 100,000 100,000 0 0
Declaration of Trust for the
Defined Benefit Plans of
ZENECA Holdings Inc. 65,000 65,000 0 0
Delaware PERS 720,000 720,000 0 0
Delaware State Employees'
Retirement Fund 335,000 335,000 0 0
Deutsche Bank Securities 0 0 0 0
Donaldson, Lufkin & Jenrette
Securities Corporation 0 0 0 0
Fidelity American Trust 0 0 0 0
Fidelity Financial Trust
Fidelity Convertible
Securities Fund 0 0 0 0
Forest Alternative Strategies
Fund II Series A-5I 0 0 0 0
Forest Alternative Strategies
Fund II LP Series A-5 0 0 0 0
Forest Alternative Strategies
Fund II LP Series A-5M 0 0 0 0
Forest Alternative Strategies
Fund Series B-3 0 0 0 0
Forest Global Convertible
Fund Series A-5 0 0 0 0
Forest Global Convertible
Fund Series B-1 0 0 0 0
Forest Global Convertible
Fund Series B-2 0 0 0 0
Forest Global Convertible
Fund Series B-3 0 0 0 0
Forest Global Convertible
Fund Series B-5 0 0 0 0
</TABLE>
2.
<PAGE> 3
<TABLE>
<CAPTION>
PRINCIPAL
AMOUNT OF
NOTES OWNED PRINCIPAL COMMON STOCK COMMON STOCK
PRIOR TO AMOUNT OF NOTES OWNED PRIOR TO OFFERED
NAME OFFERING(1) OFFERED HEREBY OFFERING(1)(2) HEREBY
---- ---------- ---------- ---------- ----------
<S> <C> <C> <C> <C>
Forest Greyhound 0 0 0 0
Forest Performance Fund 0 0 0 0
Forum Capital Markets L.P. 1,000,000 1,000,000 0 0
Fox Family Foundation 10/10/87 0 0 0 0
Fox Family Portfolio
Partnership 0 0 0 0
Hawaiian Airlines Inc. FBO
Pension Plan for Employees
Rep. By the IAM 120,000 120,000 0 0
Hawaiian Airlines Inc. UAD
1/1/76 FBO Pension Plan for
Salaried Individual (SAL) 30,000 30,000 0 0
Heritage Series Trust Small
Cap Stock Fund 1,000,000 1,000,000 100,000 0
ICI American Holdings 310,000 310,000 0 0
The James and Abigail
Campbell Foundation 75,000 75,000 0 0
Jeffries and Company Inc. 20,000 20,000 0 0
JMG Convertible Investments,
L.P. 500,000 500,000 0 0
Kapiolani Health 80,000 80,000 0 0
LDG Limited 150,000 150,000 0 0
Little Wing L.P. 0 0 0 0
Lincoln National Convertible
Securities Fund 1,700,000 1,700,000 0 0
LLT Limited 0 0 0 0
MainStay Convertible Fund 0 0 68,800 0
Maui Publishing Company
Retirement Plan 10,000 10,000 0 0
McMahan Securities Company
L.P. 505,000 505,000 0 0
Minnesota Bakers Union
Pension Fund 30,000 30,000 0 0
Morgan Stanley Dean Witter 0 0 0 0
Nalco Chemical Company 160,000 160,000 0 0
Navesink Equity Derivative
Fund, LDC 2,000,000 2,000,000 0 0
</TABLE>
3.
<PAGE> 4
<TABLE>
<CAPTION>
PRINCIPAL
AMOUNT OF
NOTES OWNED PRINCIPAL COMMON STOCK COMMON STOCK
PRIOR TO AMOUNT OF NOTES OWNED PRIOR TO OFFERED
NAME OFFERING(1) OFFERED HEREBY OFFERING(1)(2) HEREBY
---- ---------- ---------- ---------- ----------
<S> <C> <C> <C> <C>
Northwestern Mutual Life
Insurance Company 0 0 0 0
OCM Convertible Limited
Partnership 50,000 50,000 0 0
OCM Convertible Trust 1,315,000 1,315,000 0 0
Pacific Life Insurance Company 3,000,000 3,000,000 0 0
Paloma Securities L.L.C 1,500,000 1,500,000 0 0
Partner Reinsurance Company,
Ltd. 225,000 225,000 0 0
Pepperdine University Pool A#1 175,000 175,000 0 0
Sage Capital 1,450,000 1,450,000 0 0
Schroders & Co. Inc. 250,000 250,000 0 0
Silverton International Fund
Limited 1,500,000 1,500,000 0 0
Societe Generale Securities
Corp. 6,370,000 6,370,000 0 0
SSI Balanced Hedge Partnership 45,000 45,000 0 0
State Employees' Retirement
Fund of the State of Delaware 360,000 360,000 0 0
State of Connecticut Combined
Investment Funds 1,280,000 1,280,000 0 0
Thermo Eletron Balanced
Investment Fund 0 0 0 0
TQA Leverage Fund, L.P. 1,100,000 1,100,000 0 0
TQA Vantage Fund, LTD 2,300,000 2,300,000 0 0
TQA Vantage Plus, LTD 450,000 450,000 0 0
Tracor, Inc. Employees
Retirement Plan 110,000 110,000 0 0
Trade Winds L.P. 0 0 0 0
Triton Capital Investments,
Ltd. 500,000 500,000 0 0
Twin City Bakery Drivers
Pension Fund 20,000 20,000 0 0
Unity House 80,000 80,000 0 0
Vanguard Convertible
Securities Fund, Inc. 0 0 0 0
Walker Art Center 50,000 50,000 0 0
</TABLE>
4.
<PAGE> 5
<TABLE>
<CAPTION>
PRINCIPAL
AMOUNT OF
NOTES OWNED PRINCIPAL COMMON STOCK COMMON STOCK
PRIOR TO AMOUNT OF NOTES OWNED PRIOR TO OFFERED
NAME OFFERING(1) OFFERED HEREBY OFFERING(1)(2) HEREBY
---- -------------- ----------------- --------------- ------------
<S> <C> <C> <C> <C>
Weirton Trust 200,000 200,000 0 0
Zeneca Holdings Trust 310,000 310,000 0 0
-------------- -------------- ------- -
TOTAL $38,705,000.00 $38,705,000.00 239,516 0
============== ============== ======= =
</TABLE>
(1) Beneficial ownership is determined in accordance with the Rule of the
SEC and generally includes voting or investment power with respect to
securities. Except as otherwise indicated by footnote, and subject to
community property laws where applicable, the persons named in the table
have sole voting and investment power with respect to all shares on
Common Stock shown as beneficially owned by them. Numbers reflect
ownership prior to the date of this Supplement.
(2) Includes Conversion Shares based on a conversion price of $30.904 per
share and a cash payment in lieu of any fractional interest.
Because the Selling Securityholders may offer all or some of the Notes
that they hold and/or Conversion Shares pursuant to the offering
contemplated by this Prospectus, and because there are currently no
agreements, arrangements or understandings with respect to the sale of
any of the Notes or Conversion Shares by the Selling Securityholders, no
estimate can be given as to the principal amount of Notes or Conversion
of Shares that will be held by the Selling Securityholders after
completion of this offering.
5.
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