PHARMACIA & UPJOHN INC
S-8, 1995-11-02
PHARMACEUTICAL PREPARATIONS
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<PAGE> 1
  As filed with the Securities and Exchange Commission on November 2, 1995

                                                  Registration No. 33-_____





                     SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, DC 20549

                                  FORM S-8

                           REGISTRATION STATEMENT
                                 UNDER THE
                           SECURITIES ACT OF 1933

                          Pharmacia & Upjohn, Inc.
           (Exact Name of Registrant as Specified in Its Charter)

                                  Delaware
       (State or Other Jurisdiction of Incorporation or Organization)

                                 98-0155411
                    (I.R.S. Employer Identification No.)

               Fleming Way, Crawley, Sussex RH10 2LZ, England
            (Address of Principal Executive Offices) (Zip Code)

                    Management Incentive Program of 1982
                    Management Incentive Program of 1987
                    Management Incentive Program of 1992
                           (Full Title of Plans)

                              Kenneth M. Cyrus
                           Fleming Way, Crawley, 
                          Sussex RH10 2LZ England
                  (Name and Address of Agent For Service)

                           011 (44-123) 953-1133
        Telephone Number, Including Area Code, of Agent For Service.

                      CALCULATION OF REGISTRATION FEE

 Title of                         Proposed     Proposed     
Securities                        Offering     Aggregate
  to be          Amount to be     Price Per    Offering         Amount of
Registered        Registered      Share(1)     Price(1)     Registration Fee

Common Stock,
par value
$.01 per share    15,757,512       $11.70     $184,362,890     $63,573.41

      (1)   The price  shown is the pro  forma book value per  share of the
Common Stock  on June 30, 1995,  in accordance with Rule  457(h)(i), and is
being utilized solely for the purpose of calculating the registration fee.









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                                   PART I

                   INFORMATION REQUIRED IN THE PROSPECTUS


Item 1.     Plan Information

            Effective as of November 2, 1995, Pharmacia & Upjohn, Inc. (the
"Company") assumed the outstanding stock options (the "Upjohn Options"), of
The  Upjohn Company  ("Upjohn") issued  pursuant to  the Upjohn  Management
Incentive  Program  of  1982  (the  "Upjohn   1982  Program"),  the  Upjohn
Management  Incentive Program of  1987 (the "Upjohn  1987 Program") and the
Upjohn Management Incentive Program of 1992 (the "Upjohn 1992 Program", and
together  with the Upjohn  1982 Program and  1987 Program, the "Programs").
Each outstanding Upjohn Option issued under the Programs has been converted
into an option (each a  "Company Option") to purchase the number  of shares
of Common Stock,  par value $.01  per share, of  the Company (the  "Company
Common Stock") as shall  be equal to the number of shares  of Upjohn Common
Stock, par value $1 per share, which  could have been purchased immediately
prior to November 2, 1995 (the effective time of the merger  of Pharmacia &
Upjohn Subsidiary, Inc. and Upjohn) under such Upjohn Option, multiplied by
1.45, and  at an option exercise  price per share, of  Company Common Stock
equal  to the  per share  option exercise  price specified  in  such Upjohn
Option, divided by 1.45.   All references in the Programs to Upjohn are, as
a result  of such assumption,  deemed to refer  to the Company.   All other
information  required  by Part  I  to be  contained  in  the Section  10(a)
prospectus is omitted from  this Registration Statement in accordance  with
Rule  428 under  the Securities  Act of  1933, as amended  (the "Securities
Act") and the "Note" to Part I of Form S-8.

Item 2.     Registrant  Information  and  Employee  Plan Annual
            Information

            Any documents  which  the Company  has  agreed to  provide  are
available  by  contacting the  Company  at Fleming  Way,  Crawley, Fleming,
Sussex  RH10 2LZ, England  (011) (44-123) 953-1133.   All other information
required  by Part  I to  be contained  in the  Section 10(a)  prospectus is
omitted from this Registration Statement in accordance  with Rule 428 under
the Securities Act and the "Note" to Part I of Form S-8.

<PAGE>
<PAGE> 3

                                  PART II

             INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


Item 3.     Incorporation of Documents by Reference.

            The documents listed on (a) through  (c) below are incorporated
herein by reference.

            (a)   Prospectus dated September  15, 1995 filed as part of the
Company's Registration Statement on Form S-4 (File No. 33-61969).

            (b)   None.

            (c)   The description of  the Company's Common Stock  contained
in  the Company's  Registration Statement  on Form  8-A (File  No. 1-11557)
filed with the Securities and Exchange Commission on October 24, 1995.

            All  documents subsequently  filed by  the Company  pursuant to
Section 13(a), 13(c), 14 and 15(d)  of the Securities Exchange Act of 1934,
as  amended,  prior  to the  filing  of  a  post-effective amendment  which
indicates that all securities  offered have been sold or  which deregisters
all securities then remaining unsold, shall be deemed to be incorporated by
reference in the  Registration Statement and  to be  part thereof from  the
date of filing of such documents.

Item 4.     Description of Securities.

            Not applicable.

Item 5.     Interests of Named Experts and Counsel.

            Not Applicable.

Item 6.     Indemnification of Officers and Directors.

            Section 145 of the  Delaware General Corporation Law authorizes
a court to award, or a corporation's board of directors to grant, indemnity
to  directors and  officers  in terms  sufficiently  broad to  permit  such
indemnification  under certain  circumstances  for  liabilities  (including
reimbursement for  expenses incurred) arising  under the Securities  Act of
1933. The  Company's Certificate of  Incorporation and By-laws  provide for
indemnification of its directors,  officers, employees and other  agents to
the  maximum extent permitted by  the Delaware General  Corporation Law. In
addition,  the Company has entered into indemnification agreements with its
executive  officers and directors. The Company also intends to purchase and
maintain insurance for its officers, directors, employees or agents against
liabilities which an officer, a director, an employee or an agent may incur
in his capacity as such.

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<PAGE> 4


            For a period  of six years after November 2,  1995, the Company
will cause to be maintained in effect  the current directors' and officers'
liability insurance policies maintained  by Upjohn and Pharmacia Aktiebolag
("Pharmacia")  (provided that  the Company  may,  and in  the event  of the
cancellation or termination of  such policies, the Company will, substitute
therefore policies reasonably satisfactory to the indemnified parties of at
least the same  coverage containing terms and conditions which  are no less
advantageous)  with respect  to claims  arising from  facts or  events that
occurred prior to November 2, 1995.

            The Company has agreed that it will indemnify and hold harmless
each  present and  former  director and  officer  of Upjohn  or  Pharmacia,
determined as of  November 2, 1995,  against any Costs  (as defined in  the
Combination Agreement  among Pharmacia, Upjohn, the Company and Pharmacia &
Upjohn  Subsidiary,  Inc.   (the  "Combination  Agreement"))  incurred   in
connection  with  any claim,  action,  suit,  proceeding or  investigation,
whether civil, criminal, administrative or investigative, arising out of or
pertaining to  matters existing  or occurring  at or  prior to  November 2,
1995,  whether asserted or claimed prior to,  at or after November 2, 1995,
to the fullest  extent that Upjohn  or Pharmacia would have  been permitted
under  Delaware  or Swedish  law, as  the case  may  be, and  their charter
documents  (each  as  in  effect  on August  20,  1995)  to  indemnify such
indemnified parties (and the Company will also advance expenses as incurred
to  the fullest extent permitted  under applicable law,  provided that such
indemnified  party to whom expenses are advanced provides an undertaking to
repay  such advances if it  is ultimately determined  that such indemnified
party  is not entitled to indemnification); and provided, further, that any
determination  required to be made with respect  to whether an officer's or
director's  conduct complies with the standards set forth under Delaware or
Swedish law and Upjohn's or  Pharmacia's charter documents will be made  by
independent counsel selected by the Company.

            To  the  extent  the  foregoing provision  does  not  serve  to
indemnify  and  hold  harmless an  Indemnified  Party  (as  defined in  the
Combination Agreement),  for a period  of six years  after the date  of the
Combination Agreement, the Combination  Agreement provides that the Company
will,  subject to  the  terms  set  forth  in  the  Combination  Agreement,
indemnify  and  hold  harmless,  to  the  fullest  extent  permitted  under
applicable  law (and the Company will also  advance expenses as incurred to
the  fullest extent  permitted  under  applicable  law; provided  that  the
Indemnified  Party to whom expenses are advanced provides an undertaking to
repay  such advances if it  is ultimately determined  that such Indemnified
Party is not entitled  to indemnification), each Indemnified  Party against
any Costs incurred in  connection with any claim, action,  suit, proceeding
or investigation, whether civil, criminal, administrative or investigative,
arising  out of  or  pertaining to  the  transactions contemplated  by  the
Combination  Agreement; provided,  however, that  the Company  will not  be
required to indemnify any  Indemnified Party if  it is determined that  the
Indemnified  Party acted in bad faith and  not in a manner such Indemnified
Party believed to be in  or not opposed to the best interests  of Upjohn or
Pharmacia, as the case may be.

Item 7.     Exemption from Registration Claim.

            Not Applicable.

<PAGE>
<PAGE> 5

Item 8.     Exhibits.

            The following exhibits  are filed as part  of this Registration
Statement:


Exhibit No.       Description

      3.1         Form  of  Restated Certificate  of  Incorporation  of the
                  Company (incorporated by reference to Exhibit 3(a) to the
                  Company's  Registration Statement on  Form S-4  (File No.
                  33-61969)).

      3.2         Form of by-laws of the Company (incorporated by reference
                  to Exhibit 3(b)  to the Company's  Registration Statement
                  on Form S-4 (file No. 33-61969)).

      4.1         Specimen  Common  Stock   Certificate  (incorporated   by
                  reference  to Exhibit  5  to  the Company's  Registration
                  Statement on Form 8-A (File No. 1-11557).

      4.2         The  Company  Management and  Incentive  Program of  1992
                  (incorporated by reference  to Exhibit 10(d) to  Upjohn's
                  Annual Report  on Form 10-K  for the year  ended December
                  31, 1994 (File No. 1-4147) and amendment dated August 19,
                  1995.

      4.3         Portions of the Company  Management and Incentive Program
                  of 1987 relating to the 1987 Stock Option Plan and amendment
                  dated August 19, 1995.

      4.4         Portions of the Company Management and  Incentive Program
                  of 1982 relating to the 1982 Stock Option Plan and amendment
                  dated August 19, 1995.

      5(a)        Opinion  of Sullivan & Cromwell as to the validity of the
                  Company Common Stock.

      5(b)        Opinion  of Shearman & Sterling as to the validity of the
                  Company Common Stock.

      23.1        Consent of Sullivan &  Cromwell (contained in Exhibit 5.1
                  attached hereto).

      23.2        Consent of Shearman &  Sterling (contained in Exhibit 5.2
                  attached hereto).

      23.3        Consent of Coopers and Lybrand, LLP.

      23.4        Consent of Ohrlings Coopers and Consent
                  of KPMG Bohlins AB.

      23.5        Consent of KPMG Peat Marwick LLP.

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<PAGE> 6

Item 9.     Undertakings

            (a)   The undersigned Registrant hereby undertakes:

                  (1)  To file, during any period in which offers or  sales
are being made, a  post-effective amendment to this registration  statement
to  include  any  material   information  with  respect  to  the   plan  of
distribution not previously disclosed in the  Registration Statement or any
material change to such information in the Registration Statement;

                  (2)   That, for the  purpose of determining any liability
      under the Securities Act of  1933, each such post-effective amendment
      shall be  deemed to be a  new registration statement relating  to the
      securities offered therein,  and the offering  of such securities  at
      that  time shall  be  deemed to  be  the initial  bona fide  offering
      thereof; and

                  (3)   To  remove from  registration by  means of  a post-
      effective  amendment any  of  the securities  being registered  which
      remain unsold at the termination of the offering.

            (b)   The  undersigned Registrant  hereby undertakes  that, for
purposes of determining  any liability  under the Securities  Act of  1933,
each filing of the Registrant's annual  report pursuant to Section 13(a) or
Section 15(d) of the  Securities Exchange Act of 1934 that  is incorporated
by  reference in  the Registration Statement  shall be  deemed to  be a new
registration statement relating to the securities offered therein,  and the
offering of  such securities at that time shall be deemed to be the initial
bona fide offering thereof.

            (c)   Insofar as indemnification for liabilities  arising under
the  Securities Act  of 1933 may  be permitted  to directors,  officers and
controlling persons  of the registrant pursuant to the foregoing provision,
or otherwise,  the Registrant has been  advised that in the  opinion of the
Securities and  Exchange Commission such indemnification  is against public
policy as expressed in the Securities Act and is, therefore, unenforceable.
In  the event  that a  claim for  indemnification against  such liabilities
(other than the payment by the Registrant of expenses incurred or paid by a
director, officer or controlling person of the Registrant in the successful
defense of any action,  suit or proceeding) is  asserted by such  director,
officer  or  controlling person  in  connection with  the  securities being
registered, the Registrant will, unless  in the opinion of its counsel  the
matter  has been  settled by controlling  precedent, submit  to a  court of
appropriate jurisdiction the question whether such indemnification by it is
against  public policy  as expressed  in  the Securities  Act  and will  be
governed by the final adjudication of such issue.

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                                 SIGNATURES

            Pursuant to the requirements of the Securities Act of 1933, the
Registrant  certifies that  it has  reasonable grounds  to believe  that it
meets all of the  requirements for filing on  Form S-8 and has duly  caused
this Registration  Statement to be signed on its behalf by the undersigned,
thereunto duly  authorized, in the City of London, England, on this 2nd day
of November, 1995.

                                          PHARMACIA & UPJOHN, INC.



                                    By:     /s/ Robert C. Salisbury     
                                          Robert C. Salisbury
                                          Chief Executive Officer


            Pursuant  to the requirements of the Securities Act of 1933, as
amended,  this  Registration Statement  has  been signed  by  the following
persons in the indicated capacities on November 2, 1995.


                Signature                       Title



           /s/ Mats Pettersson                  Chairman of the Board
               Mats Pettersson


           /s/ Robert C. Salisbury              Chief Executive Officer and
               Robert C. Salisbury              Director


           /s/ Mats Lidgard                     Chief Accounting Officer and
               Mats Lidgard                     Director


           /s/ Kenneth M. Cyrus                 Chief Financial Officer and
               Kenneth M. Cyrus                 Director


           /s/ Goran Ando                       Director
               Goran Ando

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           /s/ Philip Carra                     Director
               Philip Carra


           /s/ Don W. Schmitz                   Director
               Don W. Schmitz


           /s/ Anna Rogmark                     Director
               Anna Rogmark



<PAGE> 1
 
                                                              Exhibit 4.2

                             AMENDMENT TO THE
                UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1992


            Effective immediately prior to the consummation of the merger

contemplated by the Combination Agreement, dated August 20, 1995, among the

Company, Pharmacia Aktiebolag, Pharmacia & Upjohn, Inc. and Pharmacia &

Upjohn Subsidiary, Inc., Section 7.09(c) of The Upjohn Management Incentive

Program of 1992 is hereby amended by the addition of the paragraph below

immediately following the end of the first sentence thereof:

            Notwithstanding anything in the foregoing to the
      contrary, for purposes of Sections 6.04(k), 6.05(d) and 7.09(a)
      and (b), no change in control shall be deemed to have occurred
      by virtue of the occurrence of any of the following events: 
      (i) the consummation of the merger contemplated by the
      Combination Agreement, dated August 20, 1995, among the
      Company, Pharmacia Aktiebolag ("Pharmacia"), Pharmacia &
      Upjohn, Inc. and Pharmacia & Upjohn Subsidiary, Inc., or any
      other related transaction with Pharmacia (the "Transaction"),
      (ii) any report filed on Form 8-K as a result of the
      Transaction or (iii) any change in the Board of Directors of
      the Company as a result of the Transaction; provided, however,
      that each outstanding Option shall vest and be exercisable
      immediately prior to the effective date of the Transaction
      (other than Options held by officers of the Company subject to
      Section 16 of the Exchange Act, which shall vest and become
      exercisable if the employment of any such officer terminates
      other than for cause, prior to the date the Option becomes
      exercisable in full).



<PAGE> 1
     
                                                               Exhibit 4.3















              THE UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1987

<PAGE>
<PAGE> 2

              THE UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1987



            1.    Purposes.  The purposes of this Program are (a) to

provide additional incentive and reward to executives and key personnel who

contribute to the success of the Company and its subsidiaries by their

invention, ability, industry, loyalty or exceptional service, through

making them participants in that success; (b) to attract to and retain in

the employ of the Company and its subsidiaries, individuals of outstanding

competence; and (c) to encourage the ownership by such individuals of stock

of the Company or otherwise further the identity of their interests with

those of the Company's stockholders generally.  The Program is composed of

the Incentive Compensation Plan of 1987, the 1987 Stock Option Plan and the

1987 Performance Share Plan.

            2.    Definitions.  Unless otherwise required by the context,

the terms used in this Program shall have the meanings set forth in this

Section 2.  

            2.01  ADJUSTED EARNINGS BEFORE TAX:  The Net Earnings of the

Company for a Compensation Year (a) before deduction of or allowance for

any of the following:

            (i)   federal taxes of the United States and foreign go-
      vernments (including, but without limitation thereto, excess profits
      taxes) based upon or measured, in whole or in part, by income of the
      Company and its Subsidiaries but exclusive of state and territorial
      taxes and taxes imposed by political subdivisions thereof;

            (ii)  incentive compensation awards under the Program for such
      Compensation Year and for any prior Compensation Years;

            (iii) all items of capital or non-recurring loss or other
      extraordinary charge which, by reason of size, character or other
      factors, do not arise in the ordinary and usual course of business of
      the Company or its Subsidiaries, including, without limitation,
      losses due to fluctuations in foreign currency or currencies; except
      that, when computing Adjusted Earnings Before Tax of the Company for
      purposes of this section for any Compensation Year, the Board of
      Directors in its discretion shall have 

<PAGE>
<PAGE> 3

power, on or before December 31 of such Compensation Year, to direct that
any such item of loss or charge shall be deducted, in whole or in part, in
determining Adjusted Earnings Before Tax of the Company for such
Compensation Year;

and (b) after deduction of and allowance for all of the following if and to

the extent not theretofore fully deducted or allowed for in computing Net

Earnings of the Company;

            (i)   all items of capital gain, non-recurring profit or other
      extraordinary credit which, by reason of size, character or other
      factors, do not arise in the ordinary and usual course of the
      business of the Company or its Subsidiaries including, without
      limitation, profits due to fluctuations in foreign currency or
      currencies; except that, when computing adjusted before-tax profits
      of the Company for purposes of this section for any Compensation
      Year, if the Board of Directors finds in its discretion that the
      Incentive Compensation Group has been instrumental in producing any
      such item of gain, profit or credit, the Board shall have power, on
      or before December 31 of such Compensation Year, to direct that such
      item shall be included, in whole or in part, in determining Adjusted
      Earnings Before-Tax of the Company for such Compensation Year;

            (ii)  such special write-offs and reserves as the independent
      accounting firm employed by the Company as its auditors may recommend
      or the Board of Directors may, in its discretion, deem advisable, so
      that the Board may exercise the fullest degree of conservative
      prudent judgment in making write-offs and in setting up reserves
      against contingencies and for all other purposes, including (but
      without limitation thereto) write-offs of inventory and special
      reserves against unremitted foreign earnings based on currency
      restrictions, devaluation or other similar or dissimilar factors;
      provided, however, that, for the purpose of computing Aggregate
      Incentive Compensation for any Compensation Year, the Board of
      Directors in its discretion shall have power, on or before December
      31 of such Compensation Year, to direct that any such write-off or
      reserve shall be excluded, in whole or in part, in determining
      Adjusted Earnings Before-Tax of the Company for such Compensation
      Year;

            (iii) unearned portions or installments of incentive
      compensation awards credited to income of the Company.

            2.02  AGGREGATE INCENTIVE COMPENSATION:  The aggregate amount

available for incentive compensation awards for a particular Compensation

Year, composed of the Aggregate Target Fund, as adjusted, and the

Supplemental Fund, as determined by the Board of Directors on

recommendation of the Incentive Committee, which shall in no event 

<PAGE>
<PAGE> 4



exceed for any Compensation Year, five percent (5%) of the amount, if any,

by which the Adjusted Earnings Before Tax of the Company exceeds an amount

which is 15% of Shareholders' Equity (consolidated total assets less

consolidated total liabilities) as reported in the audited consolidated

balance sheets of the Company as of December 31 of the preceding

Compensation Year.

            2.03  AGGREGATE TARGET FUND:  The sum of the Target Awards for

each participant in the Incentive Compensation Group.

            2.04  BENEFICIARY:  As applied to a Participant, a person or

entity (including a trust or the estate of the Participant) designated

pursuant to rules of general application of the Incentive Committee, in a

written document executed by the Participant in such form as shall be

approved by the Incentive Committee, to receive, in the event of the death

of the Participant, the unpaid balance of an award of incentive

compensation, Options, Stock Appreciation Rights or of a Performance Share

Award.  If, at the time when an unpaid balance of an Incentive Compensation

Award or Performance Share Award shall be or become payable or an Option or

Stock Appreciation Right shall be exercisable, at or after the death of the

Participant, there shall not be any living person or any entity in

existence so designated, the term "Beneficiary" shall mean the executors or

administrators of the Participant's estate.



            2.05  BOARD or BOARD OF DIRECTORS:  The Board of Directors of

the Company.

<PAGE>
<PAGE> 5



            2.06  COMMON STOCK:  The common stock of the Company, par value

$1.00 per share, or such other class of shares or other securities as may

be applicable pursuant to the provisions of Section 4 below.

            2.07  COMPANY:  The Upjohn Company, a Delaware corporation.

            2.08  COMPENSATION YEAR:  A calendar year for which the Program

is in effect.

            2.09  DIVIDEND EQUIVALENT:  As applied to a Participant who has

elected to receive payment of the unpaid portion of an award in or measured

by the value of shares of Common Stock, an amount equal to each dividend,

other than a dividend in Common Stock, which would have been received by

the Participant in respect of shares of the Common Stock (giving effect to

any adjustments under Section 4 below) in which such unpaid portion of his

award shall at the time be payable or by the value of which payment of such

unpaid portion shall be measured, if such shares of Common Stock had been

transferred to such Participant on the date on which the award was made and

had been retained by him up to and including the record date for payment of

such dividend.

            2.10  ELIGIBLE EMPLOYEE:  An officer of the Company or other

salaried Employee including a director who is such an officer or salaried

Employee.

            2.11  EMPLOYEE:  An individual employed by the Company or a

Subsidiary.

            2.12  FAIR MARKET VALUE:  As applied to a specific date, the

average of the highest and lowest quoted selling prices of Common Stock on

sales, regular way, reported for such date for New York Stock Exchange

issues on the consolidated stock exchange 

<PAGE>
<PAGE> 6



network or, if Common Stock was not traded on such date, on the next

preceding day on which the Common Stock was so traded.

            2.13  INCENTIVE COMMITTEE:  The Incentive Committee to

administer the Program appointed pursuant to Section 3 below.

            2.14  (a) INCENTIVE COMPENSATION GROUP:  As applied to a

Compensation Year, the Employees selected by the Incentive Committee for

such Compensation Year pursuant to 6.02 below.

            (b)   INCENTIVE STOCK OPTION:  A form of Option which meets all

of the requirements set forth under Section 422A(b) of the Internal Revenue

Code of 1954, as amended.

            2.15  INTEREST EQUIVALENT RATE:  As applied to a calendar year,

the arithmetic average of annualized rates payable on six month money

market certificates as reported in the consumer savings rates table in the

Wall Street Journal on the date nearest the last business day of each

calendar month during such calendar year.

            2.16  NET EARNINGS OF THE COMPANY:  The net earnings of the

Company and its Subsidiaries for a Compensation Year, as determined for the

purpose of the annual statement of consolidated earnings for such

Compensation Year by the independent accounting firm employed by the

Company as its auditors, and in any event (a) after provision for federal

taxes of the United States and foreign governments (including, but without

limitation thereto, excess profits taxes) based upon, or measured, in whole

or in part, by income of the Company and its subsidiaries; (b) after

provision for incentive compensation 

<PAGE>
<PAGE> 7



awards for such Compensation Year; and (c) after provision for any pension,

excess benefit, profit-sharing or thrift plan for Employees.

            2.17  OPTIONS:  The options granted from time to time under the

Program.

            2.18  PARTICIPANT:  An Employee to whom an incentive compen-

sation award has been made or to whom Options, Stock Appreciation Rights or

Performance Share Awards have been granted under the Program.

            2.19  PROGRAM:  The Upjohn Management Incentive Program of 1987

set forth in these pages, as it may be amended from time to time.

            2.20  (a) RESTRICTED SHARES:  Shares of Common Stock

transferred subject to restrictions precluding a sale or other disposition

for a period of time and requiring, as a condition to retention, compliance

with any other terms and conditions imposed by the Incentive Committee.

            (b)   RETIREMENT:  Termination of employment at or after

attainment of age 65.

            2.21  SALARY:  The total compensation currently paid to an

Employee by the Company and its Subsidiaries and designated "salary" and in

any event exclusive of any Christmas bonus, of incentive compensation

awards under the Program, of any payments to or for the account of the

Employee under any pension, excess benefit, profit-sharing or thrift or

savings plan, and of fringe benefits.



            2.22  SERVICE:  Employment as a regular Employee of the Company

(including any Subsidiary of the Company).  Service shall not be considered

to have been 

<PAGE>
<PAGE> 8



terminated by disability, whether temporary or permanent, during any period

that the Participant shall be entitled to receive at least one-half the

salary paid to him immediately prior to his disability.  A Participant who

is rendering advisory services at a salary of less than one-half of the

salary that he was being paid as a full-time Employee of the Company or a

Subsidiary shall be considered to have terminated his service.

            2.23   STOCK APPRECIATION RIGHT:  A right to receive a number

of shares of Common Stock, or cash in lieu thereof, based upon the increase

in value of Common Stock, as more particularly set forth in 7.08 below.

            2.24  SUBSIDIARY:  A corporation the financial results of which

for the Compensation Year are consolidated with those of the Company for

purposes of the financial statement of consolidated earnings for such

Compensation Year included in the Company's annual report to stockholders.

            2.25  SUPPLEMENTAL FUND:  An amount equal to a percentage

determined by the Incentive Committee, of the Aggregate Target Fund, as

such fund may be adjusted pursuant to Section 6.01(a).

            2.26  TARGET AWARD:  An amount established by the Incentive

Committee for each participant in the Incentive Compensation Group.

            2.27  TREASURY STOCK:  All shares of capital stock of the

Company and of any Subsidiary issued but held in the treasury of such

corporation including, without limitation, any shares held by the Company

for the purpose of the Program.

            2.28  UNUSED LIMIT CARRYOVER:  The unused limit carryover as

defined under Section 422A(c)(4) of the Internal Revenue Code of 1954, as

amended.

<PAGE>
<PAGE> 9



            4.    Adjustments Upon Changes in Capitalization.  In the event

of a reorganization, recapitalization, stock split, stock dividend,

combination of shares, merger, consolidation, rights offering or any other

change in the corporate structure of the Company affecting shares of its

Common Stock, the Incentive Committee shall recommend and the Board of

Directors shall make appropriate adjustment (a) in respect of the unpaid

balance of any award of incentive compensation payable in or measured by

the value of shares of Common Stock, (b) in respect of any Restricted

Shares or Performance Share Awards authorized, transferred or granted under

the Program and (c) in the number and kind of shares authorized by the 1987

Stock Option Plan, in the aggregate and to any individual Employee or group

of Employees, in the number and kind of shares subject to unexercised

Options and Stock Appreciation Rights theretofore granted and in the price

of such shares.

            5.    Term of the Program.  Grants of Performance Share Awards

or incentive compensation awards may be made under the Program for each of

the five (5) calendar years 1987 to 1991, both inclusive, or any portion

thereof, and Options may be granted under the Program at any time or from

time to time during each of such five years.  Unless the Program shall be

readopted by the stockholders of the Company, no awards of incentive

compensation shall be made under the Program for any calendar year

subsequent to 1991 and no Options or Stock Appreciation Rights or

Performance Share Awards shall be granted after December 31, 1991;

provided, however, that the Incentive Committee may establish, with respect

to Performance Share Awards, an Award Period, as defined in Section 8.01,

which includes Compensation Years beginning after December 31, 1991 if the

earliest Compensation Year in such Award Period ends no later than December

31, 1991.


<PAGE>
<PAGE> 10



            7.    The 1987 Stock Option Plan

            7.01  Stock Subject to Stock Option Plan.  The shares for which

Options and Stock Appreciation Rights may be granted under the 1987 Stock

Option Plan shall be shares of the Common Stock of the Company.  Subject to

Section 8.01, the number of shares which may be purchased upon exercise of

Options that may from time to time be granted under the Program or which

may be transferred in respect of Stock Appreciation Rights shall not

exceed, in the aggregate, 1,250,000 shares of such Common Stock, a number

which shall be subject to adjustment as provided in Section 4 above.  If an

Option, or a Stock Appreciation Right, after having been granted under this

Program, shall for any reason expire or terminate without having been

exercised in full and shares shall not have been transferred nor cash paid

in respect of a Stock Appreciation Right relating to an Option so granted,

the shares theretofore subject to such Option or Stock Appreciation Right,

as the case may be, and not purchased or transferred shall be added to the

shares otherwise available for Options and Stock Appreciation Rights which

may thereafter be granted, and such shares not so purchased or transferred

shall not be deemed to increase the aggregate number of shares for which

Options and Stock Appreciation Rights may be granted.  The shares to be

transferred upon exercise of Options granted under the Program or in

respect of Stock Appreciation Rights may be made available, at the

discretion of the Board of Directors, from authorized but unissued shares

of the Company, from stock at any time held in the treasury of the Company

or from shares acquired by the Company for the purpose of the Program,

including shares purchased at any time or from time to time in the open

market.  Subject to the limitations set forth under Section 7.02 below, all

Options granted under the Program may be Incentive Stock Options.

<PAGE>
<PAGE> 11



            7.02  Number of Shares Subject to Individual Incentive Stock

Options.  There shall be no limit on the number of shares of the Common

Stock which may be purchased upon exercise of an Option or Options or which

may be transferred upon exercise of Stock Appreciation Rights granted under

the Program to any individual Employee.  The aggregate fair market value

(determined as of the time such Option is granted) of, as applicable, (i)

Common Stock for which any Employee may be granted Incentive Stock Options

in any calendar year, or (ii) Common Stock with respect to which Incentive

Stock Options granted to any Employee become, in accordance with procedures

to be established by the Committee, exercisable for the first time by such

Employee during any calendar year, (in the case of both (i) and (ii) under

the Program and all other plans, if any, which provide for the granting of

Incentive Stock Options and which are maintained by the Company, a

Subsidiary or any other affiliated corporation) shall not exceed the

maximum amount permitted by the Internal Revenue Code as it may be amended

from time to time.

            7.03  Factors to be Considered in Granting Options.  An Option

and a Stock Appreciation Right shall be granted only to an Eligible

Employee and only for a reason or reasons connected with employment.  An

Eligible Employee may be granted more than one Option and Stock

Appreciation Right subject, however, to the provisions of 7.02 above, but

only during the term of the Program.  In making any determination as to

Employees to whom Options shall be granted and as to the number of shares

for which any Option or Stock Appreciation Right shall be granted, the

Incentive Committee shall in each case take into account the duties of the

Employee, his present and potential contributions to the success of 

<PAGE>
<PAGE> 12



the Company, his compensation, and such other factors as the Incentive

Committee shall deem relevant to the accomplishment of one or more purposes

of the Program.

            7.04  Option Price.  The purchase price of the shares of the

Common Stock upon exercise of an Option granted under the Program shall be

not less than the Fair Market Value of such shares on the date the Option

is granted and in no event less than the par value thereof.

            7.05  Exercise of Options.  (a) An Option shall not be

exercisable until the optionee has completed one year of employment with

the Company or a Subsidiary from the date of grant of the Option, and shall

be exercisable after the completion of that year of employment as may be

determined by the Incentive Committee; provided, that an Incentive Stock

Option shall be subject to the sequential exercise limitation applicable to

Incentive Stock Options as set forth under 7.05(f) below.  After an Option

shall have become exercisable, all or any part of the shares subject to the

Option may be purchased at any time or from time to time thereafter during

the remainder of the term of the Option; provided, however, that except as

otherwise set forth in 7.07 below, an Option may not be exercised unless

the holder thereof shall at the time of such exercise be an Employee.

            (b)   The purchase price of the shares as to which an Option

shall be exercised shall be paid in full in cash at the time of exercise. 

Alternatively, in lieu of cash, an optionee may exercise his option by

tendering to the Company shares of the Common Stock of the Company, owned

by him, and having a Fair Market Value equal to the cash exercise price

applicable to his Option, with the Fair Market Value of such stock to be

determined in such appropriate manner as may be provided for by the

Incentive Committee or as may be required 

<PAGE>
<PAGE> 13



in order to comply with or to conform to the requirements of any applicable

or relevant laws or regulations; provided, that the Incentive Committee may

determine that an Option shall provide that the optionee may not tender

shares of the Common Stock of the Company unless such shares have been held

by the optionee for a minimum period of time specified by the Incentive

Committee.

            (c)   The holder of an Option shall not have any of the rights

of a stockholder with respect to any share subject to such Option unless

and until he shall become the holder of record of such share.

            (d)   No Option granted under the Program shall in any event,

and notwithstanding any provision of 7.05(a) above or 7.07 and 9.06 below,

be exercisable after the expiration of ten (10) years from the date on

which the Option shall have been granted.

            (e)   Each Option granted under the Program may be made

exercisable upon such other terms and conditions consistent with the

Program as shall be determined by the Incentive Committee, including

provisions to the effect that the shares subject to the Option shall be

Restricted Shares.

            (f)   Notwithstanding any other provision of the Program,

including without limitation Section 7.05(a) and Section 7.07, an Incentive

Stock Option granted to an Employee on or prior to December 31, 1986 shall

not be exercisable at any time while there is outstanding any Incentive

Stock Option previously granted to such Employee (1) to purchase Common

Stock, (2) to purchase stock of any corporation which, at the time of

granting such option, was a parent or Subsidiary of the Company or (3) to

purchase stock of a predecessor of any such corporations or of the Company. 

For these purposes an Incentive Stock Option 

<PAGE>
<PAGE> 14



shall be treated as outstanding until it is exercised in full or expires by

lapse of time as such events are determined under the applicable provisions

of the Internal Revenue Code of 1954, as amended, and any regulations,

rulings or other official pronouncements promulgated thereunder.

            7.06  Non-Transferability and Other Matters Pertaining to

Options and Stock Appreciation Rights.  An Option and any Stock

Appreciation Rights granted under the Program shall not be transferable

otherwise than by will or the laws of descent and distribution and shall be

exercisable, during the lifetime of the Employee, only by him or by his

guardian or legal representative; provided, however, that nothing in this

Program shall prevent the designation of a Beneficiary or prevent the grant

of an option or options with a readily ascertainable fair market value at

the time of grant and to that end, without limiting the generality of the

foregoing, such an option or options may be made transferable or may be

made exercisable by a person or persons other than the Employee, upon such

terms and conditions as the Incentive Committee may approve, but no option

that is so transferable or exercisable shall be deemed to have been granted

under this Program.

            7.07  Termination of Employment.  In case the employment of an

Employee to whom an Option shall have been granted shall be terminated

otherwise than as a result of death, the Option may be exercised (but,

except as otherwise provided in 7.07(b), only to the extent that the

Employee shall have been entitled to exercise the Option on the termination

of his employment) during such period after the date on which he shall have

ceased to be an Employee as shall be prescribed in the option grant. 

Subject to 7.05(d) above, such period shall be three (3) years following

termination of employment by Retirement and three (3) 

<PAGE>
<PAGE> 15



months following other termination of employment unless, prior to the

expiration of such three (3) months' period, the Incentive Committee in the

case of an officer or director of the Company, or an appropriate officer of

the Company authorized by the Chief Executive Officer of the Company in the

case of other Employees, shall have determined that such other termination

of employment is not adverse to the interests of the Company and shall have

authorized in writing a three (3) year period following such termination

for exercise of the Option; provided, however, that a lesser period or

periods for exercise following Retirement or other termination of

employment may be prescribed by the Incentive Committee upon or prior to

the option grant.  Subject to 7.05(d) above, if an Employee to whom an

Option shall have been granted shall die while he shall be employed by the

Company or one of its Subsidiaries or during the period after the

termination of his employment within which the Option shall be exercisable

pursuant to this 7.07 (a), the Option may be exercised (but only to the

extent that the Employee shall have been entitled to exercise the Option

immediately prior to his death) within one (1) year from the date of the

Employee's death, unless a lesser period for such exercise shall have been

prescribed in the option grant.

            7.08  Stock Appreciation Rights.  (a) Stock Appreciation Rights

may be granted in connection with any Option granted under the Program,

either at the time of the grant of such Option or at any time thereafter

during the term of the Option, or may be granted independently of the grant

of an Option.  Stock Appreciation Rights may also be granted in connection

with any option heretofore or hereafter granted under any prior stock

option plans of the Company, or as an addition to or substitution for

options or stock appreciation rights granted under such plans or under the

Program.

<PAGE>
<PAGE> 16



            (b)   If granted in connection with an Option, Stock

Appreciation Rights shall entitle the holder of the related Option, upon

exercise of such Stock Appreciation Rights, to surrender the Option, or any

portion thereof, to the extent unexercised, and to receive a number of

shares of Common Stock, or cash, determined pursuant to clause (c)(iii) of

this paragraph 7.08.  Such Option shall, to the extent so surrendered,

thereupon cease to be exercisable.  If granted independently of an Option,

Stock Appreciation Rights shall entitle the holder of the Stock

Appreciation Rights to receive a number of shares of Common Stock, or cash,

determined pursuant to clause (c)(iii) of this paragraph 7.08.

            (c)   Stock Appreciation Rights shall be subject to the

following terms and conditions and to such other terms and conditions not

inconsistent with the Program as shall from time to time be approved by the

Incentive Committee:

            (i)   If granted in connection with an Option, Stock
      Appreciation Rights shall be exercisable at such time or times and to
      the extent, but only to the extent, that the Option to which they
      relate shall be exercisable.  If granted independently of an Option,
      Stock Appreciation Rights shall be exercisable at such time or times
      as shall be determined by the Incentive Committee at the time of the
      grant of the Stock Appreciation Rights but in no event later than the
      period provided in 7.07(a) for exercise of an Option.

            (ii)  Stock Appreciation, Rights shall in no event be
      exercisable unless and until the holder of the Stock Appreciation
      Rights shall have completed at least twelve months of continuous
      Service with the Company or a Subsidiary, or both, immediately
      following the date upon which the Stock Appreciation Rights shall
      have been granted.  Whether authorized leaves of absence or absence
      for military or government service shall constitute termination of
      employment or interruption of continuous employment for purposes of
      the Program shall be determined by the Incentive Committee.

            (iii) Upon exercise of Stock Appreciation Rights, the holder
      thereof shall be entitled to receive a number of shares equal in Fair
      Market Value to the amount by which the Fair Market Value of one
      share of Common Stock on the date of such exercise shall exceed the
      Fair Market Value of a share of Common Stock on the date of grant of
      the related Option if such Stock Appreciation Rights were granted in
      connection with an Option or on the date of grant of such Stock
      Appreciation Rights if 

<PAGE>
<PAGE> 17

      such Stock Appreciation Rights were granted independently of an
      Option, multiplied by the number of shares in respect of which the
      Stock Appreciation Rights shall have been exercised.  The Incentive
      Committee may authorize settlement of all or any part of the
      Company's obligation arising out of an exercise of Stock Appreciation
      Rights by the payment of cash equal to the aggregate value of shares
      of Common Stock (or a fraction of a share) that the Company would
      otherwise be obligated to deliver under the preceding sentence of
      this Section 7.08(c)(iii).

            (d)   To the extent that Stock Appreciation Rights shall be

exercised, an option in connection with which such Stock Appreciation

Rights shall have been granted shall be deemed to have been exercised for

the purpose of the maximum limitations set forth in the Program.  In the

case of Stock Appreciation Rights granted independently of an option, the

number of shares of Common Stock in respect of which such Stock

Appreciation Rights shall be exercised shall be charged against such

maximum limitations.

            (e)   If so directed by the Incentive Committee, the grant of

Stock Appreciation Rights may provide for payment from time to time to the

holder of the Stock Appreciation Rights, either in cash or in shares of

Common Stock, of amounts not exceeding the cash dividends, as and when

declared or paid, which would have been paid in respect of a number of

shares of Common Stock equal to the number of shares subject to the Stock

Appreciation Rights if such shares have been issued or transferred to the

holder of the Stock Appreciation Rights from the time the Stock

Appreciation Rights were granted to such holder to the time when they shall

be exercised or shall lapse or otherwise terminate.

            (f)   An Employee and, in the event of his death, his

Beneficiary or the person or persons to whom the related Option or Stock

Appreciation Rights shall have been transferred by will or the laws of

descent and distribution, shall have no rights as a 

<PAGE>
<PAGE> 18



shareholder with respect to any shares subject to Stock Appreciation Rights

until the date of issuance to him of a stock certificate for such shares.

            7.09  Cash Payment for options upon Change in Control.  (a)

Notwithstanding any other provision of the program or of any outstanding

Option, in the event of a change in control the Company shall pay to each

optionee with respect to each Option held by the optionee, excluding (1)

Incentive Stock Options outstanding on June 21, 1988 and (2) options held

by officers of the Company elected by the Board of Directors which are not

exercisable on the date of such change in control, an amount in cash, which

shall be payable within ten days after the change in control, equal to the

difference between (i) the result of multiplying (A) the number of shares

of Common Stock subject to each Option which have not been exercised by (B)

the market value of the Common Stock and (ii) the aggregate purchase price

for such shares.  Upon such payment, all Options for which such cash

payment is made (and any related Stock Appreciation Rights) shall be

cancelled. 

            (b)   If an officer of the Company elected by the Board of

Directors holds an Option (other than an Incentive Stock Option outstanding

on June 21, 1988) which is not exercisable in full on the date of a change

in control and such officer remains in employment with the Company or a

Subsidiary until the date such Option becomes exercisable, then,

notwithstanding any other provision of the Program or of the Option, the

Company shall pay to such officer on each date on which all or a portion of

such Option becomes exercisable an amount equal to the difference between

(1) the result of multiplying (i) the number of shares of Common Stock

subject to such Option that first become exercisable on that date by (ii)

the market value of the Common Stock and (2) the aggregate purchase price

for such shares.  If 

<PAGE>
<PAGE> 19



the employment of such officer terminates other than for cause, prior to

the date all shares of Common Stock subject to such option becomes

exercisable, the Company shall pay to such officer (or, in the event of the

officer's death, to the estate of the officer) within ten days following

termination of employment an amount equal to the difference between (A) the

result of multiplying (x) the number of shares of Common Stock subject to

such Option that were not exercisable upon termination of employment by (v)

the market value of the Common Stock and (B) the aggregate purchase price

for such shares.  Upon payment, pursuant to this paragraph, all options for

which such cash payment is made (and any related Stock Appreciation Rights)

shall be cancelled.

            (c)   The Incentive Committee may, in its discretion, amend the

terms of Incentive Stock Options outstanding on June 21, 1988 to include

provisions for cash payments similar to the provisions of 7.09(a) and (b)

above.

            (d)   For purposes of this Section, a "change in control" shall

mean a change in control of a nature that would be required to be reported

in response to Item 1(a) of the Current Report on Form 8-K, as in effect on

June 21, 1988, pursuant to Section 13 or 15 (d) of the Securities Exchange

Act of 1934 (the "Exchange Act"), provided that, without limitation, such a

change in control shall be deemed to have occurred at such time as (1) any

"person", within the meaning of Section 14(d) of the Exchange Act, other

than the Company or any employee benefit plan(s) sponsored by the Company,

is or becomes the "beneficial owner" (as defined in Rule 13d-3 under the

Exchange Act), directly or indirectly, of 25% or more of the Common Stock,

or (2) individuals who constitute the Board of Directors of the Company on

June 21, 1988 (the "Incumbent Board") cease for any reason to constitute at

least

<PAGE>
<PAGE> 20



a majority thereof, provided that any person becoming a director subsequent

to such date whose election, or nomination for election by the Company's

stockholders, was approved by a vote of at least three-quarters of the

directors comprising the Incumbent Board (either by a specific vote or by

approval of the proxy statement of the Company in which such person is

named as a nominee for director, without objection to such nomination)

shall be, for purposes of this clause (d), considered as though such person

were a member of the Incumbent Board.  In addition, for purposes of this

Section, "market value" shall mean (i) in the event the change in control

is the result of a cash tender offer for all of the Common Stock, the cash

paid to shareholders in such tender offer or (ii) otherwise, the highest

Fair Market Value of the Common Stock during the ten trading day period

preceding the change in control.  For purposes of this Section, "cause"

means (a) the willful and continued failure by an officer of the Company

elected by the Board of Directors to substantially perform his duties for

the Company (other than such failure resulting from incapacity due to

physical or mental illness) after a written demand for substantial

performance is delivered to the officer by the Chairman of the Board of

Directors or President of the Company which specifically identifies the

manner in which such executive believes that the officer has not

substantially performed his duties, or (b) the willful engaging by the

officer in illegal conduct which is materially and demonstrably injurious

to the Company.

<PAGE>
<PAGE> 21



            9.    General Provisions

            9.01  Neither the adoption of the Program nor its operation,

nor any booklet or other document describing or referring to the Program,

or any part thereof, shall confer upon any Employee any right to continue

in the employ of the Company or any Subsidiary, or shall in any way affect

the right and power of the Company or any Subsidiary to dismiss or

otherwise terminate the employment of any Employee at any time for any

reason with or without cause.  If the Company shall terminate the

employment of a Participant for any reason, whether or not for cause, the

Company shall incur no liability to the Participant due to the inability of

the Participant by reason of such termination to exercise thereafter any

Option or Stock Appreciation Right theretofore granted to the Participant

by the Company or to receive payment of any award under the Program or to

be eligible thereafter for any award or grant of an Option or Stock

Appreciation Right under the Program.

            9.02  By accepting participation in or any benefits under the

Program, each member of the Incentive Compensation Group, each Participant,

and each person claiming under or through him, shall be conclusively deemed

to have indicated his acceptance and ratification of, and consent to, any

action or decision taken or made or to be taken or made under the Program

by the Company, the Board of Directors and the Incentive Committee.

            9.03  Appropriate provision shall be made for all taxes

required to be withheld from incentive compensation awards, and in

connection with Options and Stock Appreciation Rights and the exercise

thereof and in connection with payment of Performance Share Awards, under

the applicable laws or other regulations of any governmental authority,

whether Federal, state or local and whether domestic or foreign, including,

but not limited to, the withholding 

<PAGE>
<PAGE> 22



of payment of all or any portion of such award or the transfer of shares

pursuant to exercise of an Option or a Stock Appreciation Right until the

Participant reimburses the Company for the amount the Company believes to

be required to be withheld with respect to such taxes, or cancelling any

portion of an award in an amount sufficient to reimburse itself for the

amount it believes to be required to be so withheld, or selling any

property contingently credited by the Company for the purpose of paying

such award, in order to withhold or reimburse itself for the amount it

believes to be required to be so withheld.

            9.04  The place of administration of the Program shall be

conclusively deemed to be within the State of Delaware and the validity,

construction, interpretation and administration of the Program and of any

rules and regulations or determinations or decisions made thereunder, and

the rights of any and all persons having or claiming to have any interest

therein or thereunder shall be governed by, and determined exclusively and

solely in accordance with, the laws of the State of Delaware.  Without

limiting the generality of the foregoing, the period within which any

action arising under or in connection with the Program, or any payment or

award made or purportedly made under or in connection therewith, must be

commenced shall be governed by the laws of the State of Delaware,

irrespective of the place where the act or omission complained of took

place and of the residence of any party to such action and irrespective of

the place where the action may be brought.

            9.05  Any communication under the Program to the Board of

Directors shall be deemed to have been delivered to the Board when

delivered to the Secretary of the Company for transmission to the Board,

irrespective of whether the Board shall then be in 

<PAGE>
<PAGE> 23



session.  Any communication under the Program to the Incentive Committee

shall be deemed to have been delivered to the Incentive Committee when

delivered to the Secretary of the Incentive Committee for transmission to

the Incentive Committee, irrespective of whether the Incentive Committee

shall then be in session.

            9.06   If any day on or before which action under the Program

must be taken falls on a Saturday, Sunday or legal holiday, such action may

be taken on the next succeeding day not a Saturday, Sunday or legal

holiday.

            10.   Amendment or Repeal.  The Program, subject to the

provisions of 10.01 and 10.02 below, may be amended or repealed by the

stockholders of the Company or, if, as and when the Inventive Committee

shall recommend, but not otherwise, by the Board of Directors.

            10.01 Only the stockholders of the Company may amend the

provisions of the Program

            (a)   so as to increase Aggregate Incentive Compensation for

any Compensation Year above that authorized by the provisions of the

Program, but amendment of the Program so as to change the form or terms of

payment of incentive compensation awards from those provided in the Program

shall not be deemed to increase Aggregate Incentive Compensation provided

the Fair Market Value of all property transferred in payment of Incentive

Compensation Awards shall not exceed Aggregate Incentive Compensation, nor

shall Aggregate Incentive Compensation be deemed increased as the result of

an increase in value of capital stock or other property in which an award

under the Program shall be payable or by 

<PAGE>
<PAGE> 24



which payment of an award shall be measured or of any dividends, Dividend

Equivalents, interest, interest equivalents or similar increment paid or

payable in respect of any award;

            (b)   so as to increase the maximum number of shares which may

be purchased upon exercise of Options granted under the Program,

transferred in respect of Stock Appreciation Rights or transferred or paid

in respect of Performance Share Awards, except as authorized by Section 4

above, or so as to decrease the minimum option price provided for in 7.04

above, except as so authorized;

            (c)    so as materially to increase the benefits accruing to

Participants under the Program or materially to modify the requirements as

to the eligibility for Participants in the Program;

            (d)   so as to extend the term of the Program or the period

during which options may be exercised;

            (e)   so as to change the provisions of 3.01 above relating to

the Incentive Committee; or

            (f)   so as to change the provisions of this Section 10.

            10.02 The provisions of the Program, as in effect on November

15 of any Compensation Year, shall in all respects remain in effect with

respect to any incentive compensation award, or installment thereof, made

or to be made or payable for such Compensation Year, notwithstanding the

amendment or repeal of the Program subsequent to November 15 of such

Compensation Year by either the Board of Directors or the stockholders. 

Neither the termination of the Program by expiration or otherwise, nor any

amendment thereof shall, without the consent of the Participant, adversely

affect his rights under an unexpired 

<PAGE>
<PAGE> 25



Option, Stock Appreciation Right or Performance Share Award granted to him,

or under an incentive compensation award made to him, prior to such

termination or amendment.
<PAGE>
<PAGE> 1

                              AMENDMENT TO THE
                UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1987


            Effective immediately prior to the consummation of the merger

contemplated by the Combination Agreement, dated August 20, 1995, among the

Company, Pharmacia Aktiebolag, Pharmacia & Upjohn, Inc. and Pharmacia &

Upjohn Subsidiary, Inc., Section 7.09(d) of The Upjohn Management Incentive

Program of 1987 is hereby amended by the addition of the paragraph below

immediately following the end of the first sentence thereof:

            Notwithstanding anything in the foregoing to the
      contrary, for purposes of 7.09(a) and (b), no change in control
      shall be deemed to have occurred by virtue of the occurrence of
      any of the following events:  (i) the consummation of the
      merger contemplated by the Combination Agreement, dated
      August 20, 1995, among the Company, Pharmacia Aktiebolag
      ("Pharmacia"), Pharmacia & Upjohn, Inc. and Pharmacia & Upjohn
      Subsidiary, Inc., or any other related transaction with
      Pharmacia (the "Transaction"), (ii) any report filed on Form 8-
      K as a result of the Transaction or (iii) any change in the
      Board of Directors of the Company as a result of the
      Transaction.





<PAGE> 1
                                                      Exhibit 4.4

















              THE UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1982




<PAGE>
<PAGE> 2



              THE UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1982

      1.        Purposes

                The purposes of this Program are (a) to provide additional

incentive and reward to executives and key personnel who contribute to the

success of the Company and its subsidiaries by their invention, ability,

industry, loyalty or exceptional service, through making them participants

in that success; (b) to attract to and retain in the employ of the Company

and its subsidiaries, individuals of outstanding competence; and (c) to

encourage the ownership by such individuals of stock of the Company or

otherwise further the identity of their interests with those of the

Company's stockholders generally. The Program is composed of the Incentive

Compensation Plan of 1982 and the 1982 Stock Option Plan.

      2.        Definitions

                Unless otherwise required by the context, the terms used in

this Program shall have the meanings set forth in this Section 2.

      2.01      AGGREGATE INCENTIVE COMPENSATION:  The aggregate amount

available for incentive compensation awards for a particular Compensation

Year computed as set forth in 6.01 below.

      2.02      BENEFICIARY:  As applied to a Participant, a person or

entity (including a trust or the estate of the Participant) designated

pursuant to rules of general application of the Incentive Committee, in a

written document executed by the Participant in such form as shall be

approved by the Incentive 

<PAGE>
<PAGE> 3



Committee, to receive, in the event of the death of the Participant, the

unpaid balance of an award of incentive compensation or an Option or Stock

Appreciation Rights.  If at the time when an unpaid balance of an award

shall be or become payable or an Option or Stock Appreciation Rights shall

be exercisable, at or after the death of the Participant, there shall not

be any living person or any entity in existence so designated, the term

"Beneficiary" shall mean the executors or administrators of the

Participant's estate.

      2.03      BOARD or BOARD OF DIRECTORS:  The Board of Directors of the

Company.

      2.04      COMMON STOCK:  The common stock of the Company, par value

$1.00 per share, or such other class of shares or other securities as may

be applicable pursuant to the provisions of Section 4 below.

      2.05      COMPANY:  The Upjohn Company, a Delaware corporation.

      2.06      COMPENSATION YEAR:  A calendar year for which the Program

is in effect.

      2.07      DIVIDEND EQUIVALENT:  As applied to a Participant who has

elected to receive payment of the unpaid portion of an award in or measured

by the value of shares of Common Stock, an amount equal to each dividend,

other than a dividend in Common Stock, which would have been received by

the Participant in respect of shares of the Common Stock (giving effect to

any adjustments under Section 4 below) in which such unpaid portion 

<PAGE>
<PAGE> 4



of his award shall at the time be payable or by the value of which payment

of such unpaid portion shall be measured, if such shares of Common Stock

had been transferred to such Participant on the date on which the award was

made and had been retained by him up to and including the record date for

payment of such dividend.

      2.08      ELIGIBLE EMPLOYEE:  An officer of the Company or other

salaried Employee including a director who is such an officer or salaried

Employee.

      2.09      EMPLOYEE:  An individual employed by the Company or a

Subsidiary.

      2.10      FAIR MARKET VALUE:  As applied to a specific date, the

average of the highest and lowest quoted selling prices of Common Stock on

sales, regular way, reported for such date for New York Stock Exchange

issues on the consolidated stock exchange network or, if Common Stock was

not traded on such date, on the next preceding day on which the Common

Stock was so traded.

      2.11      INCENTIVE EASE:  The amount by which the total consolidated

assets of the Company and its Subsidiaries (including net assets of foreign

Subsidiaries) other than Treasury Stock exceed the total liabilities of the

Company and its Subsidiaries other than capital stock, as computed by the

independent accounting firm employed by the Company as its auditors

pursuant to the provisions of 6.01(c) below.

      2.12      INCENTIVE COMMITTEE:  The Incentive Committee to administer

the Program appointed pursuant to Section 3 below.

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<PAGE> 5



      2.13      (a)    INCENTIVE COMPENSATION GROUP:  As applied to a

Compensation Year, the Employees selected by the Incentive Committee for

such Compensation Year pursuant to 6.02 below.

                (b)    INCENTIVE STOCK OPTION:  A form of Option which

meets all of the requirements set forth under Section 422A(b) of the

Internal Revenue Code of 1954, as amended.

      2.14      (a)    INCREASE IN INCENTIVE BASE:  The amount by which the

Incentive Base at the close of business on December 31 of the calendar year

next preceding the Compensation Year for which incentive compensation

awards are to be made shall exceed the Incentive Base at the close of

business on December 31, 1980.

                (b)    INTEREST EQUIVALENT RATE:  As applied to a calendar

year, the higher of (a) the highest annual rate that mutual savings banks

shall have been permitted to pay, under the Regulations of the Federal

Deposit Insurance Corporation, on regular savings accounts at any time

during such calendar year, or (b) the arithmetic average of annualized

rates payable on six month money market certificates as reported in the

Wall Street Journal for the last business day of each calendar month during

such calendar year.

      2.15      NET BEFORE-TAX PROFITS OF THE COMPANY:  The Net Earnings of

the Company for a Compensation Year (a) before deduction of or allowance

for any of the following:

                (i)     federal taxes of the United States and foreign
      governments (including, but without limitation thereto, excess
      profits taxes) based upon or measured, in whole or in part, by income
      of the Company and its 

<PAGE>
<PAGE> 6

      Subsidiaries but exclusive of state and territorial taxes and taxes
      imposed by political subdivisions thereof;

               (ii)     incentive compensation awards under the Program for
      such Compensation Year and for any prior Compensation Years;

              (iii)     all items of capital or non-recurring loss or other
      extraordinary charge which, by reason of size, character or other
      factors, do not arise in the ordinary and usual course of business of
      the Company or its Subsidiaries, including, without limitation,
      losses due to fluctuations in foreign currency or currencies; except
      that, for the purpose of computing Aggregate Incentive Compensation
      for any Compensation Year, the Board of Directors in its discretion
      shall have power, on or before December 31 of such Compensation Year,
      to direct that any such item of loss or charge shall be deducted, in
      whole or in part, in determining Net Before-Tax Profits of the
      Company for such Compensation Year;

and (b) after deduction of and allowance for all of the following if and to

the extent not theretofore fully deducted or allowed for in computing Net

Earnings of the Company;

                (i)     all items of capital gain, non-recurring profit or
      other extraordinary credit which, by reason of size, character or
      other factors, do not arise in the ordinary and usual course of the
      business of the Company or its Subsidiaries including, without
      limitation, profits due to fluctuations in foreign currency or
      currencies; except that, for the purpose of computing Aggregate
      Incentive Compensation for any Compensation Year, if the Board of
      Directors finds in its discretion that the Incentive Compensation
      Group has been instrumental in producing any such item of gain,
      profit or credit, the Board shall have power, on or before December
      31 of such Compensation Year, to direct that such item shall be
      included, in whole or in part, in determining Net Before-Tax Profits
      of the Company for such Compensation Year;

               (ii)     such special write-offs and reserves as the
      independent accounting firm employed by the Company as its auditors
      may recommend or the Board of Directors may, in its discretion, deem
      advisable, so that the Board may exercise the fullest degree of
      conservative prudent judgment in making write-offs and in setting up
      reserves against contingencies and for all other purposes, including
      (but without limitation thereto) write-offs of inventory and 

<PAGE>
<PAGE> 7

      special reserves against unremitted foreign earnings based on
      currency restrictions, devaluation or other similar or dissimilar
      factors; provided, however, that, for the purpose of computing
      Aggregate Incentive Compensation for any Compensation Year, the Board
      of Directors in its discretion shall have power, on or before
      December 31 of such Compensation Year, to direct that any such write-
      off or reserve shall be excluded, in whole or in part, in determining
      Net Before-Tax Profits of the Company for such Compensation Year;

              (iii)     unearned portions or installments of incentive
      compensation awards credited to income of the Company.

      2.16      NET EARNINGS OF THE COMPANY:  The net earnings of the

Company and its Subsidiaries for a Compensation Year, as determined for the

purpose of the annual statement of consolidated earnings for such

Compensation Year by the independent accounting firm employed by the

Company as its auditors, and in any event (a) after provision for federal

taxes of the United States and foreign governments (including, but without

limitation thereto, excess profits taxes) based upon or measured, in whole

or in part, by income of the Company and its Subsidiaries; (b) after

provision for incentive compensation awards for such Compensation Year; and

(c) after provision for any pension, excess benefit, profit-sharing or

thrift plan for Employees.

      2.17      OPTIONS:  The options granted from time to time under the

Program.

      2.18      PARTICIPANT:  An Employee to whom an incentive compensation

award has been made or to whom an Option has been granted under the

Program.

<PAGE>
<PAGE> 8



      2.19      PROGRAM:  The Upjohn Management Incentive Program of 1982

set forth in these pages, as it may be amended from time to time.

      2.20      (a)    RESTRICTED SHARES:  Shares of Common Stock

transferred subject to restrictions precluding a sale or other disposition

for a period of time and requiring as a condition to retention compliance

with any other terms and conditions imposed by the Incentive Committee.

                (b)    RETIREMENT:  Termination of employment at or after

attainment of age 65.

      2.21      SALARY:  The total compensation currently paid to an

Employee by the Company and its Subsidiaries and designated "salary" and in

any event exclusive of any Christmas bonus, of incentive compensation

awards under the Program, of any payments to or for the account of the

Employee under any pension, excess benefit, profit-sharing or thrift or

savings plan, and of fringe benefits.

      2.22      SERVICE:  Employment as a regular Employee of the Company

(including any Subsidiary of the Company).  Service shall not be considered

to have been terminated by disability, whether temporary or permanent,

during any period that the Participant shall be entitled to receive at

least one-half the salary paid to him immediately prior to his disability. 

A Participant who is rendering advisory services at a salary of less than

one-half of the salary that he was being paid as a full-time Employee of

the 

<PAGE>
<PAGE> 9



Company or a Subsidiary shall be considered to have terminated his service.

      2.23      STOCK APPRECIATION RIGHT:  A right to receive a number of

shares of Common Stock, or cash in lieu thereof, based upon the increase in

value of Common Stock, as more particularly set forth in 7.08 below.

      2.24      SUBSIDIARY:  A corporation the financial results of which

for the Compensation Year are consolidated with those of the Company for

purposes of the financial statement of consolidated earnings for such

Compensation Year included in the Company's annual report to stockholders.

      2.25      TREASURY STOCK:  All shares of capital stock of the Company

and of any Subsidiary issued but held in the treasury of such corporation

including, without limitation, any shares held by the Company for the

purpose of the Program.

      2.26      UNUSED LIMIT CARRYOVER:  The unused limit carryover as

defined under Section 422A(c)(4) of the Internal Revenue Code of 1954, as

amended

<PAGE>
<PAGE> 10



Page 12

      4.        Adjustments Upon Changes in Capitalization

                In the event of a reorganization, recapitalization, stock

split, stock dividend, combination of shares, merger, consolidation, rights

offering or any other change in the corporate structure of the Company

affecting shares of its Common Stock, the Incentive Committee shall

recommend and the Board of Directors shall make appropriate adjustment (a)

in respect of the unpaid balance of any award of incentive compensation

payable in or measured by the value of shares of Common Stock, (b) in

respect of any Restricted Shares transferred under the Program and (c) in

the number and kind of shares authorized by the 1982 Stock Option Plan, in

the aggregate and to any individual Employee or group of Employees, in the

number and kind of shares subject to unexercised Options and Stock

Appreciation Rights theretofore granted and in the price of such shares.

<PAGE>
<PAGE> 11



Page 28

      7.        The 1982 Stock Option Plan

      7.01      Stock Subject to Stock Option Plan

                The shares for which Options and Stock Appreciation Rights

may be granted under the 1982 Stock Option Plan shall be shares of the

Common Stock of the Company.  The number of shares which may be purchased

upon exercise of Options that may from time to time be granted under the

Program or which may be transferred in respect of Stock Appreciation Rights

shall not exceed, in the aggregate, 800,000 shares of such Common Stock, a

number which shall be subject to adjustment as provided in Section 4 above. 

If an Option, or a Stock Appreciation Right, after having been granted

under this Program, shall for any reason expire or terminate without having

been exercised in full and shares shall not have

<PAGE>
<PAGE> 12



Pages 29-

been transferred nor cash paid in respect of a Stock Appreciation Right

relating to an Option so granted, the shares theretofore subject to such

Option or Stock Appreciation Right, as the case may be, and not purchased

or transferred shall be added to the shares otherwise available for

(options and Stock Appreciation Rights which may thereafter be granted, and

such shares not so purchased or transferred shall not be deemed to increase

the aggregate number of shares for which options and Stock Appreciation

Rights may be granted.  The shares to be transferred upon exercise of

Options granted under the Program or in respect of Stock Appreciation

Rights may be made available, at the discretion of the Board of Directors,

from authorized but unissued shares of the Company, from stock at any time

held in the treasury of the Company or from shares acquired by the Company

for the purpose of the Program, including shares purchased at any time or

from time to time in the open market.  Subject to the limitations set forth

under Section 7.02 below, all Options granted under the Program may be

Incentive Stock Options, and Incentive Stock Options may be substituted for

or converted from outstanding but unexercised stock options theretofore

granted by the Company under the Program, the 1977 Stock Option Plan or the

1972 Stock Option Plan, with the consent of the holders of such options;

shares purchased under such substituted or converted Incentive Stock

Options shall be charged only against the number of shares authorized by

the stock option 

<PAGE>
<PAGE> 13



plan under which such outstanding but unexercised stock options were

granted.

      7.02      Number of Shares Subject to Individual Options

                The number of shares of the Common Stock which may be

purchased upon exercise of an Option or Options or which may be transferred

upon exercise of Stock Appreciation Rights granted under the Program to any

individual Employee shall not exceed in the aggregate 20,000, a number

which shall be subject to adjustment as provided in Section 4 above.  With

respect to any Incentive Stock Option granted after December 31, 1980, the

aggregate fair market value (determined as of the time such Option is

granted) of Common Stock for which any Employee may be granted Incentive

Stock Options in any calendar year under the Program (and under all other

plans, if any, which provide for the granting of Incentive Stock Options

and which are maintained by the Company, a Subsidiary or any other

affiliated corporation) shall not exceed $100,000 plus any Unused Limit

Carryover to such year.

      7.03      Factors to be Considered in Granting Options

                An Option and a Stock Appreciation Right shall be granted

only to an Eligible Employee and only for a reason or reasons connected

with employment.  An Eligible Employee may be granted more than one Option

and Stock Appreciation Right subject, however, to the provisions of 7.02

above, but only during the term of the Program.  In making any

determination as to Employees to whom Options shall be granted and as to

the 

<PAGE>
<PAGE> 14



number of shares for which any Option or Stock Appreciation Right shall be

granted, the Incentive Committee shall in each case take into account the

duties of the Employee, his present and potential contributions to the

success of the Company, his compensation, and such other factors as the

Incentive Committee shall deem relevant to the accomplishment of one or

more purposes of the Program.

      7.04      Option Price

                The purchase price of the shares of the Common Stock upon

exercise of an option granted under the Program shall be not less than the

Fair Market Value of such shares on the date the Option is granted and in

no event less than the par value thereof.

      7.05      Exercise of Options

                (a)    An Option shall not be exercisable until the

optionee has completed one year of employment with the Company or a

Subsidiary from the date of grant of the Option, and shall be exercisable

in full after the completion of that year of employment; provided, that an

Incentive Stock Option shall be subject to the sequential exercise

limitation applicable to Incentive Stock Options as set forth under 7.05(f)

below.  After an Option shall have become exercisable, all or any part of

the shares subject to the Option may be purchased at any time or from time

to time thereafter during the remainder of the term of the Option;

provided, however, that except as otherwise set forth in 

<PAGE>
<PAGE> 15



7.07 below, an Option may not be exercised unless the holder thereof shall

at the time of such exercise be an Employee.

                (b)    The purchase price of the shares as to which an

Option shall be exercised shall be paid in full in cash at the time of

exercise.  Alternatively, in lieu of cash, an optionee may exercise his

option by tendering to the Company shares of the Common Stock of the

Company, owned by him, and having a Fair Market Value equal to the cash

exercise price applicable to his Option, with the Fair Market Value of such

stock to be determined in such appropriate manner as may be provided for by

the Incentive Committee or as may be required in order to comply with or to

conform to the requirements of any applicable or relevant laws or

regulations; provided, that the Incentive Committee may determine that an

Option shall provide that the optionee may not tender shares of the Common

Stock of the Company unless such shares have been held by the optionee for

a minimum period of time specified by the Incentive Committee.

                (c)    The holder of an Option shall not have any of the

rights of a stockholder with respect to any share subject to such Option

unless and until he shall become the holder of record of such share.

                (d)    No Option granted under the Program shall in any

event, and notwithstanding any provision of 7.05(a) above or 7.07 and 8.06

below, be exercisable after the expiration of ten (10) years from the date

on which the Option shall have been granted.

<PAGE>
<PAGE> 16



                (e)    Each Option granted under the Program may be made

exercisable upon such other terms and conditions consistent with the

Program as shall h)e determined by the Incentive Committee, including

provisions to the effect that the shares subject to the Option shall be

Restricted Shares.

                (f)    Notwithstanding any other provision of the Program,

including without limitation Section 7.05(a) and Section 7.07, an Incentive

Stock option granted to an Employee shall not be exercisable at any time

while there is outstanding any Incentive Stock Option previously granted to

such Employee (1) to purchase Common Stock, (2) to purchase stock of any

corporation which at the time of granting such option, was a parent or

Subsidiary of the Company or (3) to purchase stock of a predecessor of any

such corporations or of the Company.  For these purposes an Incentive Stock

Option shall be treated as outstanding until it is exercised in full or

expires by lapse of time as such events are determined under the applicable

provisions of the Internal Revenue Code of 1954, as amended, and any

regulations, rulings or other official pronouncements promulgated

thereunder.

      7.06      Non-Transferability and Other Matters Pertaining to Options
                and Stock Appreciation Rights

                An Option and any Stock Appreciation Rights granted under

the Program shall not be transferable otherwise than by will or the laws of

descent and distribution and shall be exercisable, during the lifetime of

the Employee, only by him or 

<PAGE>
<PAGE> 17



by his guardian or legal representative; provided, however, that nothing in

this Program shall prevent the designation of a Beneficiary or prevent the

grant of an option or options with a readily ascertainable fair market

value at the time of grant and to that end, and, without limiting the

generality of the foregoing, such an option or options may be made

transferable or may be made exercisable by a person or persons other than

the Employee, upon such terms and conditions as the Incentive Committee may

approve, but no option that is so transferable or exercisable shall be

deemed to have been granted under this Program.

      7.07      Termination of Employment

                (a)    In case the employment of an Employee to whom an

Options shall have been granted shall be terminated otherwise than as a

result of death, the Option may be exercised [but, except as otherwise

provided in 7.07(b), only to the extent that the Employee shall have been

entitled to exercise the Option on the termination of his employment]

during such period after the date on which he shall have ceased to be an

Employee as shall be prescribed in the option grant.  Subject to 7.05(d)

above, such period shall be three (3) years following termination of

employment by Retirement and three (3) months following other termination

of employment unless, prior to the expiration of such three (3) months'

period, the Incentive Committee in the case of an officer or director of

the Company, or an appropriate officer of the Company authorized by the

Chief Executive Officer of the 

<PAGE>
<PAGE> 18



Company in the case of other Employees, shall have determined that such

other termination of employment is not adverse to the interests of the

Company and shall have authorized in writing a three (3) year period

following such termination for exercise of the Option; provided, however,

that a lesser period or periods for exercise following Retirement or other

termination of employment may be prescribed by the Incentive Committee upon

or prior to the option grant.  Subject to 7.05(d) above, if an Employee to

whom an Option shall have been granted shall die while he shall be employed

by the Company or one of its Subsidiaries or during the period after the

termination of his employment within which the Option shall be exercisable

pursuant to this 7.07(a), the Option may be exercised (but only to the

extent that the Employee shall have been entitled to exercise the Option

immediately prior to his death) within one (1) year from the date of the

Employee's death, unless a lesser period for such exercise shall have been

prescribed in the option grant.

                (b)    Notwithstanding the provisions of 7.05(a) to the

extent prescribed by the Incentive Committee upon or prior to the option

grant, an Option held by a Participant, to the extent unexercised and

outstanding, may be accelerated, so that during the period provided in

7.07(a) it shall be exercisable as to all installments and in its entirety,

following Retirement of the Participant and, if and to the extent

authorized in writing:

                (i)     by the Incentive Committee in the case of an
      officer or director of the Company, or

<PAGE>
<PAGE> 19

               (ii)     by an appropriate officer of the Company authorized
      by the Chief Executive Officer of the Company in the case of other
      Employees, following other termination of employment of the
      Participant, provided that the Incentive Committee or such officer,
      as the case may be, shall have determined such termination of
      employment not to be adverse to the interests of the Company.

      7.08      Stock Appreciation Rights

                (a)    Stock Appreciation Rights may be granted in

connection with any Option granted under the Program, either at the time of

the grant of such Option or at any time thereafter during the term of the

Option, or may be granted independently of the grant of an Option.  Stock

Appreciation Rights may also be granted under any prior stock option plans

of the Company, or as an addition to or substitution for options or stock

appreciation rights granted under such plans or under the Program.

                (b)    If granted in connection with an Option, Stock

Appreciation Rights shall entitle the holder of the related Option, upon

exercise of such Stock Appreciation Rights, to surrender the Option, or any

portion thereof, to the extent unexercised, and to receive a number of

shares of Common Stock, or cash, determined pursuant to clause (c)(iii) of

this para- graph 7.08.  Such Option shall, to the extent so surrendered,

thereupon cease to be exercisable.  If granted independently of an Option,

Stock Appreciation Rights shall entitle the holder of the Stock

Appreciation Rights to receive a number of shares of Common Stock, or cash,

determined pursuant to clause (c)(iii) of this paragraph 7.08.

<PAGE>
<PAGE> 20



                (c)    Stock Appreciation Rights shall be subject to the

following terms and conditions and to such other terms and conditions not

inconsistent with the Program as shall from time to time be approved by the

Incentive Committee:

                (i)     If granted in connection with an Option, Stock
      Appreciation Rights shall be exercisable at such time or times and to
      the extent, but only to the extent, that the Option to which they
      relate shall be exercisable.  If granted independently of an Option,
      Stock Appreciation Rights shall be exercisable at such time or times
      as shall be determined by the Incentive Committee at the time of the
      grant of the Stock Appreciation Rights but in no event later than the
      period provided in 7.07(a) for exercise of an Option.

               (ii)     Stock Appreciation Rights shall in no event be
      exercisable unless and until the holder of the Stock Appreciation
      Rights shall have completed at least twelve months of continuous
      Service with the Company or a Subsidiary, or both, immediately
      following the date upon which the Stock Appreciation Rights shall
      have been granted.  Whether authorized leaves of absence or absence
      for military or government service shall constitute termination of
      employment or interruption of continuous employment for purposes of
      the Program shall be determined by the Incentive Committee.

              (iii)     Upon exercise of Stock Appreciation Rights, the
      holder thereof shall be entitled to receive a number of shares equal
      in Fair Market Value to the amount by which the Fair Market Value of
      one share of Common Stock on the date of such exercise shall exceed
      the Fair Market Value of a share of Common Stock on the date of grant
      of the related Option if such Stock Appreciation Rights were granted
      in connection with an Option or on the date of grant of such Stock
      Appreciation Rights if such Stock Appreciation Rights were granted
      independently of an Option, multiplied by the number of shares in
      respect of which the Stock Appreciation Rights shall have been
      exercised.  The Incentive Committee may authorize settlement of all
      or any part of the Company's obligation arising out of an exercise of
      Stock Appreciation Rights by the payment of cash equal to the
      aggregate value of shares of Common Stock (or a fraction of a share)
      that the Company would otherwise be obligated to deliver under the
      preceding sentence of this Section 7.08(c)(iii).

<PAGE>
<PAGE> 21



                (d)    To the extent that Stock Appreciation Rights shall

be exercised, an option in connection with which such Stock Appreciation

Rights shall have been granted shall be deemed to have been exercised for

the purpose of the maximum limitations set forth in the Program.  In the

case of Stock Appreciation Rights granted independently of an Option, the

number of shares of Common Stock in respect of which such Stock

Appreciation Rights shall be exercised shall be charged against such

maximum limitations.

                (e)    If so directed by the Incentive Committee, the grant

of Stock Appreciation Rights may provide for payment from time to time to

the holder of the Stock Appreciation Rights, either in cash or in shares of

Common Stock, of amounts not exceeding the cash dividends, as and when

declared or paid, which would have been paid in respect of a number of

shares of Common Stock equal to the number of shares subject to the Stock

Appreciation Rights if such shares have been issued or transferred to the

holder of the Stock Appreciation Rights from the time the Stock

Appreciation Rights were granted to such holder to the time when they shall

be exercised or shall lapse or otherwise terminate.

                (f)    An Employee and, in the event of his death, his

Beneficiary or the person or persons to whom the related Option or Stock

Appreciation Rights shall have been transferred by will or the laws of

descent and distribution, shall have no rights as a shareholder with

respect to any shares subject to 

<PAGE>
<PAGE> 22



Stock Appreciation Rights until the date of issuance to him of a stock

certificate for such shares.

      7.09      Cash Payment for Options Upon Change in Control

                (a)    Notwithstanding any other provision of the program

or of any outstanding Option, in the event of a change in control the

Company shall pay to each optionee with respect to each Option held by the

optionee, excluding (1) Incentive Stock Options outstanding on June 21,

1988 and (2) Options held by officers of the Company elected by the Board

of Directors which are not exercisable on the date of such change in

control, an amount in cash, which shall be payable within ten days after

the changed in control, equal to the difference between (i) the result of

multiplying (A) the number of shares of Common Stock subject to each Option

which have not been exercised by (B) the market value of the Common Stock

and (ii) the aggregate purchase price for such shares.  Upon such payment,

all Options for which such cash payment is made (and any related Stock

Appreciation Rights) shall be cancelled

                (b)    If an officer of the Company elected by the Board of

Directors holds an Option (other than an Incentive Stock Option outstanding

on June 21, 1988) which is not exercisable in full on the date of a change

in control and such officer remains in employment with the Company or a

Subsidiary until the date such Option becomes exercisable, then,

notwithstanding any other provision of the Program or of the Option, the

Company shall pay to such officer on each date of which all or portion of

such 

<PAGE>
<PAGE> 23



Option becomes exercisable an amount equal to the difference between (1)

the result of multiplying (i) the number of shares of Common Stock subject

to such Option that first become exercisable on that date by (ii) the

market value of the Common Stock and (2) the aggregate purchase price for

such shares.  If the employment of such officer terminates other than for

cause, prior to the date all shares of Common Stock subject to such Option

becomes exercisable, the Company shall pay to such officer (or, in the

event of the officer's death, to the estate of the officer) within ten days

following termination of employment an amount equal to the difference

between (A) the result of multiplying (x) the number of shares of Common

Stock subject to such Option that were not exercisable upon termination of

employment by (v) the market value of the Common Stock and (B) the

aggregate purchase price for such shares.  Upon payment, pursuant to this

paragraph, all Options for which such cash payment is made (and any related

Stock Appreciation Rights) shall be cancelled.

                (c)    The Incentive Committee may, in its discretion,

amend the terms of Incentive Stock Options outstanding on June 21, 1988 to

include provisions for cash payments similar to the provisions of 7.09(a)

and (b) above.

                (d)    For purposes of this Section, a "change in control"

shall mean a change of control of a nature that would be required to be

reported in response to Item 1(a) of the Current Report on Form 8-K, as in

effect on June 31, 1988, pursuant to Section 13 or 15(d) of the Securities

Exchange Act of 1934 (the 

<PAGE>
<PAGE> 24



"Exchange Act"), provided that, without limitation, such a change in

control shall be deemed to have occurred at such time as (1) any "person",

within the meaning of Section 14(d) of the Exchange Act, other than the

Company or any employee benefit plan(s) sponsored by the Company, is or

becomes the "beneficial owner" (as defined in Rule 13d-3 under the Exchange

Act), directly or indirectly, of 25% or more of the Common Stock, or

(2) individuals who constitute the Board of Directors of the Company on

June 21, 1988 (the "Incumbent Board") cease for any reason to constitute at

least a majority thereof, provided that any person becoming a director

subsequent to such date whose election, or nomination for election by the

Company's stockholders, was approved by a vote of at least three-quarters

of the directors comprising the Incumbent Board (either by a specific vote

or by approval of the proxy statement of the Company in which such person

is named as a nominee for director, without objection to such nomination)

shall be, for purposes of this clause (d), considered as though such person

were a member of the Incumbent Board.  In addition, for purposes of this

Section, "market value" shall mean (i) in the event the change in control

is the result of a cash tender offer for all of the Common Stock, the cash

paid to shareholders in such tender offer or (ii) otherwise, the highest

Fair Market Value of the Common Stock during the ten trading day period

preceding the change in control.  For purposes of this Section, "cause"

means (a) the willful and continued failure by an officer of the Company 

<PAGE>
<PAGE> 25



elected by the Board of Directors to substantially perform his duties for

the Company (other than such failure resulting from incapacity due to

physical or mental illness) after a written demand for substantial

performance is delivered to the officer by the Chairman of the Board of

Directors or President of the Company which specifically identifies the

manner in which such executive believes that the officer has not

substantially performed his duties, or (b) the willful engaging by the

officer in illegal conduct which is materially and demonstrably injurious

to the Company.

      8.        General Provisions

      8.01      Neither the adoption of the Program nor its operation, nor

any booklet or other document describing or referring to the Program, or

any part thereof, shall confer upon any Employee any right to continue in

the employ of the Company or any Subsidiary, or shall in any way affect the

right and power of the Company or any Subsidiary to dismiss or otherwise

terminate the employment of any Employee at any time for any reason with or

without cause.  If the Company shall terminate the employment of a

Participant for any reason, whether or not for cause, the Company shall

incur no liability to the Participant due to the inability of the

Participant by reason of such termination to exercise thereafter any Option

or Stock Appreciation Right theretofore granted to the Participant by the

Company or to receive payment of any award under the Program or 

<PAGE>
<PAGE> 26



to be eligible thereafter payment of any award or grant of an Option or

Stock Appreciation Right under the Program.

      8.02      By accepting participation in or any benefits under the

Program, each member of the Incentive Compensation Group, each Participant,

and each person claiming under or through him, shall be conclusively deemed

to have indicated his acceptance and ratification of, and consent to, any

action or decision taken or made or to be taken or made under the Program

by the Company, the Board of Directors and the Incentive Committee.

      8.03      Appropriate provision shall be made for all taxes required

to be withheld from incentive compensation awards, and in connection with

Options and Stock Appreciation Rights and the exercise thereof, under the

applicable laws or other regulations of any governmental authority, whether

Federal, state or local and whether domesticor foreign, including, but not

limited to, the withholding of payment of all or any portion of such award

or the transfer of shares pursuant to exercise of an Option or a Stock

Appreciation Right until the Participant reimburses the Company for the

amount the Company believes to be required to be withheld with respect to

such taxes, or cancelling any portion of an award in an amount sufficient

to reimburse itself for the amount it believes to be required to be so

withheld, or selling any property contingently credited by the Company for

the purpose of paying such award, in order to withhold or reimburse itself

for the amount it believes to be required to be so withheld.

<PAGE>
<PAGE> 27



      8.04      The place of administration of the Program shall be

conclusively deemed to be within the State of Delaware and the validity,

construction, interpretation and administration of the Program and of any

rules and regulations or determinations or decisions made thereunder, and

the rights of any and all persons having or claiming to have any interest

therein or thereunder shall be governed by, and determined exclusively and

solely in accordance with, the laws of the State of Delaware.  Without

limiting the generality of the foregoing, the period within any action

arising under or in connection with the Program, or any payment or award

made or purportedly made under or in connection therewith, must be

commenced shall be governed by the laws of the State of Delaware,

irrespective of the place where the act or omission complained of took

place and of the residence of any party to such action and irrespective of

the place where the action may be brought.

      8.05      Any communication under the Program to the Board of

Directors shall be deemed to have been delivered to the Board when

delivered to the Secretary of the Company for transmission to the Board,

irrespective of whether the Board shall then be in session.  Any

communication under the Program to the Incentive Committee shall be deemed

to have been delivered to the Incentive Committee when delivered to the

Secretary of the Incentive Committee for transmission to the Incentive

Committee, irrespective of whether the Incentive Committee shall then be in

session.

<PAGE>
<PAGE> 28



      8.06      If any day on or before which action under the Program must

be taken falls on a Saturday, Sunday or legal holiday, such action may be

taken on the next succeeding day not a Saturday, Sunday or legal holiday.

      8.07      Headings are given to the sections of the Program solely as

a convenience to facilitate reference; neither such headings nor numbering

or paragraphing shall be deemed in any way material or relevant to the

construction of the Program or any provisions thereof.

      8.08      The use of the masculine gender shall also include within

its meaning the feminine.  The use of the singular shall also include

within its meaning the plural, and vice versa.

      9.        Conforming Amendments to Prior Stock Option Plans

                The 1972 Stock Option Plan and the 1977 Stock Option Plan

of the Company may be amended by the Board of Directors to authorize the

amendment of options heretofore granted under such Plans, and, in the case

of the 1977 Stock Option Plan of any options hereafter granted, to conform

to the provisions set forth in 2.02, 7.06, 7.07 and, to the extent

applicable, 7.08(f).

      10.       Amendment or Repeal

                The Program, subject to the provisions of 10.01 and 10.02

below, may be amended or repealed by the stockholders of the Company or,

if, as and when the Incentive Committee shall recommend, but not otherwise,

by the Board of Directors.

      10.01     Only the stockholders of the Company may amend the

provisions of the Program (a) so as to increase Aggregate 

<PAGE>
<PAGE> 29



Incentive Compensation for any Compensation Year above that authorized by

the provisions of the Program, but amendment to the Program so as to change

the form or terms of payment of incentive compensation awards from those

provided in the Program shall not be deemed to increase Aggregate Incentive

Compensation provided the Fair Market Value of all property transferred in

payment of awards shall not exceed Aggregate Incentive Compensation, nor

shall Aggregate Incentive Compensation be deemed increased as the result of

an increase in value of capital stock or other property in which an award

under the Program shall be payable or by which payment of an award shall be

measured or of any dividends, Dividend Equivalents, interest, interest

equivalents or similar increment paid or payable in respect of any award;

                (b)    so as to increase the maximum number of shares which

may be purchased upon exercise of Options granted under the Program or

which may be transferred in respect of Stock Appreciation Rights either in

the aggregate or to any individual Employee, except as authorized by

Section 4 above, or so as to decrease the minimum option price provided for

in 7.04 above, except as so authorized;

                (c)    so as materially to increase the benefits accruing

to Participants under the Program or materially to modify the requirements

as to the eligibility for Participants in the Program, provided that

amendment of the Program in any respect required to authorize the grant of

Incentive Stock Options, whether in substitution for options theretofore or

<PAGE>
<PAGE> 30



thereafter granted or otherwise, shall not be deemed materially to increase

the benefits accruing to the holders of such options;

                (d)    so as to extend the term of the Program or the

period during which Options may be exercised;

                (e)    so as to change the provisions of 3.01 above

relating to the Incentive Committee; or

                (f)    so as to change the provisions of this Section 10.

      10.02     The provisions of the Program, as in effect on November 15

of any Compensation Year, shall in all respects remain in effect with

respect to any incentive compensation award, or installment thereof, made

or to be made or payable for such Compensation Year, notwithstanding the

amendment or repeal of the Program subsequent to November 15 of such

Compensation Year be either the Board of Directors or the stockholders. 

Neither the termination of the Program by expiration or otherwise, nor any

amendment thereof shall, without the consent of the Participant, adversely

affect his right under an unexpired Option or Stock Appreciation Right

granted to him, or under an incentive compensation award made to him, prior

to such termination or amendment.

                                    ****
<PAGE>
<PAGE> 1

                              AMENDMENT TO THE
                UPJOHN MANAGEMENT INCENTIVE PROGRAM OF 1982


            Effective immediately prior to the consummation of the merger

contemplated by the Combination Agreement, dated August 20, 1995, among the

Company, Pharmacia Aktiebolag, Pharmacia & Upjohn, Inc. and Pharmacia &

Upjohn Subsidiary, Inc., Section 7.09(d) of The Upjohn Management Incentive

Program of 1982 is hereby amended by the addition of the paragraph below

immediately following the end of the first sentence thereof:

            Notwithstanding anything in the foregoing to the
      contrary, for purposes of Sections 7.09(a) and (b), no change
      in control shall be deemed to have occurred by virtue of the
      occurrence of any of the following events:  (i) the
      consummation of the merger contemplated by the Combination
      Agreement, dated August 20, 1995, among the Company, Pharmacia
      Aktiebolag ("Pharmacia"), Pharmacia & Upjohn, Inc. and
      Pharmacia & Upjohn Subsidiary, Inc. or any other related
      transaction with Pharmacia (the "Transaction"), (ii) any report
      filed on Form 8-K as a result of the Transaction or (iii) any
      change in the Board of Directors of the Company as a result of
      the Transaction.



<PAGE> 1

                                                 Exhibit 5(a)
















                                                      November 2, 1995




Pharmacia & Upjohn, Inc.,
   Fleming Way,
      Crawley, Sussex RH10 2LZ,
          England.


Dear Sirs:

            In connection with the registration under the Securities Act of

1933 (the "Act") of 15,757,512 shares (the "Securities") of Common Stock,

par value $.01 per share, of Pharmacia & Upjohn, Inc. (the "Company"), a

Delaware corporation, to be offered to employees under certain incentive

plans which have been assumed by the Company from The Upjohn Company

("Upjohn"), a Delaware corporation, pursuant to the merger of Pharmacia &

Upjohn Subsidiary, Inc., a Delaware corporation wholly owned by the

Company, with and into Upjohn, we, as your special counsel, have examined

such corporate records, certificates and other documents, and such

questions of law, as we have considered necessary or appropriate for the

purposes of this opinion.  Upon the basis of such examination, we advise

you that, in 

<PAGE>
<PAGE> 2



our opinion, when the Registration Statement on Form S-8 (the "Registration

Statement") has become effective under the Act, the issue and sale of the

Securities to be sold by the Company has been duly authorized by the

Company's board of directors and the Securities have been duly issued and

sold upon the exercise of options by the employees as contemplated by the

Registration Statement, the Securities being sold by the Company will be

validly issued, fully paid and nonassessable.

            The foregoing opinion is limited to the Federal laws of the

United States, the laws of the State of New York and the General

Corporation Law of the State of Delaware, and we are expressing no opinion

as to the effect of the laws of any other jurisdiction.

            Also, we have relied as to certain matters on information

obtained from public officials, officers of the Company and other sources

believed by us to be responsible.

<PAGE>
<PAGE> 3



            We hereby consent to the filing of this opinion as an exhibit

to the Registration Statement.  In giving such consent, we do not thereby

admit that we are in the category of persons whose consent is required

under Section 7 of the Act.

                                                Very truly yours,



                                                /s/ SULLIVAN & CROMWELL


<PAGE> 1
                                                       Exhibit 5(b)

                              November 2, 1995


Pharmacia & Upjohn, Inc.
Fleming Way
Crawley, Sussex RH10 2LZ
England

Ladies and Gentlemen:

      We have acted as counsel for Pharmacia & Upjohn, Inc., a Delaware
corporation (the "Company"), and Pharmacia Aktiebolag, a corporation
organized under the laws of the Kingdom of Sweden ("Pharmacia"), in
connection with the filing by the Company with the United States Securities
and Exchange Commission of a Registration Statement on Form S-8 to which
this opinion is attached as an exhibit (the "Registration Statement")
covering the registration under the Securities Act of 1933, as amended (the
"Act"), of 15,757,512 shares (the "Shares") of the Company's common stock,
par value $.01 per share. The Shares are to be issued by the Company
pursuant to certain outstanding options to purchase common stock par value
$1.00 per share, of The Upjohn Company ("Upjohn") issued pursuant to stock
option plans of Upjohn which have been assumed by the Company pursuant to
Section 2.04(b) of the Combination Agreement dated, as of August 20, 1995,
among the Company, Pharmacia, Upjohn and Pharmacia & Upjohn Subsidiary,
Inc. (such assumed options, the "Assumed Options").

      In connection with the foregoing, we have examined originals, or
copies certified or otherwise identified to our satisfaction, of such
documents and corporate and public records as we have deemed necessary as a
basis for the opinion hereinafter expressed. In our examination, we have
assumed the genuineness of all signatures, the authenticity of all
documents presented to us as originals, the conformity to the originals of
all documents presented to us as copies, and the authenticity of the
originals of such documents. In rendering our opinion, we have relied as to
factual matters upon certificates of public officials and certificates and
representations of officers of the Company.

      Our opinion expressed herein is limited to the General Corporation
Law of the State of Delaware.

      Based on the foregoing and having regard for such legal
considerations as we deem relevant, we are of the opinion that when the
Shares have been duly issued and delivered in accordance with the terms of
the Assumed Options, the Shares will be validly issued, fully paid and non-
assessable.

      We hereby consent to the use of this opinion as Exhibit 5(b) to the
Registration Statement. In giving such consent, we do not thereby admit
that we are in the category of persons whose consent is required under
Section 7 of the Securities Act of 1933, as amended.

                                          Very truly yours,



                                          /s/  SHEARMAN & STERLING



<PAGE> 1

                                                              Exhibit 23.3

                     CONSENT OF INDEPENDENT ACCOUNTANTS


      We consent to the incorporation by reference in this registration
statement of Form S-8 of our report dated January 26, 1995, on our audits of
the consolidated financial statements of The UpJohn Company and of our report
dated August 21, 1995, on our audit of the consolidated balance sheet of 
Pharmacia & Upjohn, Inc. which reports appear in the registration statement 
on Form S-4 of Pharmacia & Upjohn, Inc.


/s/  COOPERS & LYBRAND L.L.P.

Chicago, Illinois
October 27, 1995


<PAGE> 1

                                                      Exhibit 23.4

                  CONSENT OF JOINT INDEPENDENT ACCOUNTANTS


The Board of Directors
Pharmacia AB

      We consent to the incorporation by reference in the registration 
statement of Pharmacia & Upjohn, Inc. on Form S-8 of our report dated 
March 20, 1995, on our audits of the consolidated balance sheets of 
Pharmacia AB and subsidiaries as of December 31, 1994 and 1993 and 
the related consolidated statements of income and cash flows for each 
of the three years in the period ended December 31, 1994 which report 
appears in the December 31, 1994, annual report on Form 20-F of 
Pharmacia AB.



/s/  HANS KARLSSON                        /s/  GORAN TIDSTROM
Hans Karlsson                             Goran Tidstrom
Authorized Public Accountant              Authorized Public Accountant
KPMG Bohlins AB                           Ohrlings Coopers & Lybrand AB
Member of KPMG International              Member of Coopers & Lybrand
                                            International




Stockholm, Sweden
October 27, 1995



<PAGE> 1

                                                               Exhibit 23.5

                  INDEPENDENT AUDITOR'S CONSENT


To the Board of Directors of
  Pharmacia & Upjohn, Inc.:

      We consent to the incorporation by reference in the Registration
Statement on Form S-8 of Pharmacia & Upjohn, Inc. of our report dated
August 21, 1995 relating to the consolidated balance sheet of Pharmacia &
Upjohn, Inc. as of August 21, 1995 which report appears in the Registration
Statement on Form S-4 of Pharmacia & Upjohn, Inc.



                                          /s/ KPMG Peat Marwick LLP      


Short Hills, New Jersey
October 27, 1995




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