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<PAGE> 1 Exhibit 23.1 CONSENT OF INDEPENDENT ACCOUNTANTS We hereby consent to the incorporation by reference in the Registration Statements on Form S-3 (No. 333-33786) and Form S-8 (Nos. 333-30026, 333-98514, 333-21551, and 333-52881) of Pharmacyclics, Inc. of our report dated August 14, 2000 relating to the financial statements, which appears in this Form 10-K. PricewaterhouseCoopers LLP San Jose, CA September 22, 2000
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