SONUS PHARMACEUTICALS INC
SC 13G/A, 1998-02-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  Schedule 13G

             INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2
                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                               (Amendment No. 1)*



                           Sonus Pharmaceuticals, Inc.
- --------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   0008356921
- --------------------------------------------------------------------------------
                                 (CUSIP Number)




*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                         (Continued on following pages)










                                Page 1 of 9 Pages



<PAGE>

<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 2 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Delphi Ventures III, L.P. ("DV III")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------------------------------- -------- -----------------------------------------------------------------------
                                    5        SOLE VOTING POWER
            NUMBER OF                        0 shares
              SHARES
           BENEFICIALLY
     OWNED BY EACH REPORTING
              PERSON
               WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER 
                                             0 shares.

- ----------------------------------- -------- -----------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       0
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>
*        SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>

<PAGE>

<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 3 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------

1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Delphi BioInvestments III, L.P. ("DBI III")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------- --------------------------------------------------------------------------------------------------------
                                    5        SOLE VOTING POWER
            NUMBER OF                        0 shares.
              SHARES
           BENEFICIALLY
     OWNED BY EACH REPORTING
              PERSON
               WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER 
                                             0 shares.

- ----------------------------------- -------- -----------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       0
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>



<PAGE>


<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 4 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Delphi Management Partners III, LLC ("DMP III")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
- ----------------------------------- -------- -----------------------------------------------------------------------
            NUMBER OF               5        SOLE VOTING POWER
              SHARES                         0 shares.
           BENEFICIALLY
     OWNED BY EACH REPORTING
              PERSON
               WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             0 shares.

- ----------------------------------- -------- -----------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       0
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*
                                                                                                   PN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>
*                 SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>

<PAGE>


<TABLE>
<CAPTION>
<S>                                                             <C>          <C>

- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 5 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     James R. Bochnowski ("Bochnowski")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
                                    5        SOLE VOTING POWER
            NUMBER OF                        16,103 shares.
              SHARES
           BENEFICIALLY
     OWNED BY EACH REPORTING
           PERSON WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE   DISPOSITIVE   POWER
                                             16,103 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER 
                                             0 shares.

- ----------------------------------- -------- -----------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       16,103
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.19%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*                                                              IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>
*                 SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>

<PAGE>


<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 6 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     David Douglass ("Douglass")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION
            U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
                                    5        SOLE VOTING POWER
            NUMBER OF                        0 shares.
              SHARES
           BENEFICIALLY
     OWNED BY EACH REPORTING
           PERSON WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER
                                             0 shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       0
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                                                   0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*                                                              IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>

<PAGE>



<TABLE>
<CAPTION>
<S>                                                             <C>          <C>
- --------------------------------------------------------                     ---------------------------------------
CUSIP NO. 0008356921                                            13 G                   Page 7 of 9 Pages
- --------------------------------------------------------                     ---------------------------------------

- ----------- --------------------------------------------------------------------------------------------------------
1           NAME OF REPORTING
            SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                     Donald J. Lothrop ("Lothrop")
                     Tax ID Number:
- ----------- --------------------------------------------------------------------------------------------------------
2           CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                                   (a) [ ]             (b) [X]
- ----------- --------------------------------------------------------------------------------------------------------
3           SEC USE ONLY
- ----------- --------------------------------------------------------------------------------------------------------
4           CITIZENSHIP OR PLACE OF ORGANIZATION                                                 U.S. Citizen
- ----------------------------------- -------- -----------------------------------------------------------------------
         NUMBER OF SHARES           5        SOLE VOTING POWER
           BENEFICIALLY                      0 shares.
     OWNED BY EACH REPORTING
           PERSON WITH
                                    -------- -----------------------------------------------------------------------
                                    6        SHARED VOTING POWER
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    7        SOLE DISPOSITIVE POWER 
                                             0 shares.

                                    -------- -----------------------------------------------------------------------
                                    8        SHARED DISPOSITIVE POWER 
                                             0 shares.

- ----------- --------------------------------------------------------------------------------------------------------
9           AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
            REPORTING PERSON                                                                       0
- ----------- --------------------------------------------------------------------------------------------------------
10          CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
            EXCLUDES CERTAIN SHARES*                                                                [ ]
- ----------- --------------------------------------------------------------------------------------------------------
11          PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9                                        0.00%
- ----------- --------------------------------------------------------------------------------------------------------
12          TYPE OF REPORTING PERSON*                                                              IN
- ----------- --------------------------------------------------------------------------------------------------------
<FN>

                           *   SEE INSTRUCTIONS BEFORE FILLING OUT!
</FN>
</TABLE>




<PAGE>




                                                               Page 8 of 9 Pages


                  This  Statement  amends the  Statement on Schedule  13(G) (the
"Original  Statement")  filed by Delphi  Ventures III, L.P., a Delaware  limited
partnership  ("DV III"),  Delphi  BioInvestments  III, L.P. ("DBI III"),  Delphi
Management  Partners III, LLC, a Delaware limited liability company ("DMP III"),
James R. Bochnowski ("Bochnowski"),  David Douglass ("Douglass"),  and Donald J.
Lothrop  ("Lothrop").  The foregoing  entities and individuals are  collectively
referred to as the  "Reporting  Persons." Only those items as to which there has
been a change are included in this Amendment.


ITEM 4.           OWNERSHIP

                  The following information with respect to the ownership of the
                  Common  Stock  of  the  issuer  by  the  persons  filing  this
                  Statement is provided as of December 31, 1997:

                    (a)      Amount beneficially owned:

                                   See Row 9 of cover  page  for each  Reporting
                                   Person.

                    (b)      Percent of Class:

                                   See Row 11 of cover  page for each  Reporting
                                   Person.

                    (c) Number of shares as to which such person has:

                              (i)  Sole power to vote or to direct the vote:

                                   See Row 5 of cover  page  for each  Reporting
                                   Person.

                             (ii)  Shared power to vote or to direct the vote:

                                   See Row 6 of cover  page  for each  Reporting
                                   Person.

                            (iii)  Sole power to dispose or to direct the
                                   disposition of:

                                   See Row 7 of cover  page  for each  Reporting
                                   Person.

                             (iv)  Shared power to dispose or to direct the 
                                   disposition of:

                                   See Row 8 of cover  page  for each  Reporting
                                   Person.


<PAGE>
                                                               Page 9 of 9 Pages

ITEM 5.           OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

                  If this statement is being filed to report the fact that as of
                  the date  hereof,  the  reporting  person has ceased to be the
                  beneficial  owner of more  than five  percent  of the class of
                  securities, check the following:     [X]

                                   SIGNATURES

                  After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  statement is true,
complete and correct.

Dated:  February 6, 1998



                                   /s/ James R. Bochnowski
                                   ---------------------------------------------
                                   James  R.  Bochnowski,  individually,  and on
                                   behalf of DV II, in his capacity as a general
                                   partner of DMP II, the general  partner of DV
                                   II, on behalf of DBI II, in his capacity as a
                                   general   partner  of  DMP  II,  the  general
                                   partner of DBI II, and on behalf of DMP II in
                                   his capacity as a general partner thereof.



                                   /s/ David Douglass
                                   ---------------------------------------------
                                   David Douglass



                                   /s/ Donald J. Lothrop
                                   ---------------------------------------------
                                   Donald J. Lothrop





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