NORTH AMERICAN SCIENTIFIC INC
DEF 14A, 1998-03-02
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
                            SCHEDULE 14A INFORMATION
 
                  Proxy Statement Pursuant to Section 14(a) of
            the Securities Exchange Act of 1934 (Amendment No.    )
 
    Filed by the Registrant /X/
    Filed by a party other than the Registrant / /
 
    Check the appropriate box:
    / /  Preliminary Proxy Statement
    / /  Confidential, for Use of the Commission Only (as permitted by Rule
         14a-6(e)(2))
    /X/  Definitive Proxy Statement
    / /  Definitive Additional Materials
    / /  Soliciting Material Pursuant to Section 240.14a-11(c) or Section 
         240.14a-12
 
                        NORTH AMERICAN SCIENTIFIC, INC.
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)
 
- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)
 
Payment of Filing Fee (Check the appropriate box):
 
/X/  No fee required

/ /  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) 
     and 0-11

    (1) Title of each class of securities to which transaction applies:

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    (2) Aggregate number of securities to which transaction applies:

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    (3) Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
        filing fee is calculated and state how it was determined):

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/ / Fee paid previously with preliminary materials.

/ / Check box if any part of the fee is offset as provided by Exchange Act Rule
    0-11(a)(2) and identify the filing for which the offsetting fee was paid
    previously. Identify the previous filing by registration statement number,
    or the Form or Schedule and the date of its filing.

    (1) Amount Previously Paid:

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    (4) Date Filed:

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<PAGE>


                           NORTH AMERICAN SCIENTIFIC, INC.
                                7435 GREENBUSH AVENUE
                              NORTH HOLLYWOOD, CA 91605

                                                                  March 6, 1998

Notice of Annual Stockholders Meeting:

You are hereby notified that the Annual Meeting of Stockholders of North 
American Scientific, Inc. (the "Company") will be held at the Holiday Inn 
located at 150 East Angeleno, Burbank, California at 10:00 a.m. local time, 
on Friday, April 3, 1998, for the following purposes:

1.   To elect 5 directors to hold office until the 1999 Annual Meeting. 

2.   To consider a proposal to amend the Company's Amended and Restated 1996 
Stock Option Plan.

3.   To consider a proposal to ratify the selection of Price Waterhouse LLP 
as independent auditors of the Company for the fiscal year ending October 31, 
1998.

4.   To transact such other business as may properly come before the Meeting 
or any adjournment thereof. 

The Board of Directors has fixed the close of business on February 16, 1998 
as the record date for the determination of stockholders entitled to notice 
of and to vote at the Meeting. 

You are urged to attend the Meeting in person.  Whether or not you expect to 
be present in person at the Meeting, please date, sign and return the 
enclosed proxy in the envelope provided.

                              By Order of the Board of Directors


                              /s/ L. Michael Cutrer
                              -----------------------------------------
                              L. Michael Cutrer
                              PRESIDENT

<PAGE>

                           NORTH AMERICAN SCIENTIFIC, INC.
                                ______________________

                                7435 GREENBUSH AVENUE
                              NORTH HOLLYWOOD, CA 91605

                         1998 ANNUAL MEETING OF STOCKHOLDERS
                                    APRIL 3, 1998
                                   PROXY STATEMENT

                                       GENERAL

This Proxy Statement and the accompanying proxy are furnished to stockholders 
of North American Scientific, Inc. (the "Company" ) in connection with the 
solicitation of proxies by the Company's Board of Directors for use at the 
1998 Annual Meeting of Stockholders (the "Meeting") to be held at the Holiday 
Inn located at 150 East Angeleno, Burbank, California at 10:00 a.m. local 
time, on Friday, April 3, 1998, for the purposes set forth in the 
accompanying Notice of Meeting. This Proxy Statement, the form of proxy 
included herewith and the Company's Annual Report for the fiscal year ended 
October 31, 1997, are being mailed to stockholders on or about March 6, 1998. 

Stockholders of record at the close of business on February 16, 1998 are 
entitled to notice of and to vote at the Meeting.  On such date, there were 
outstanding 4,266,201 shares of common stock, par value $0.01 per share, of 
the Company  (the "Common Stock").  The presence, in person or by proxy, of 
the holders of a majority of the shares of Common Stock outstanding and 
entitled to vote at the Meeting is necessary to constitute a quorum.  In 
deciding all questions, each holder of Common Stock shall be entitled to one 
vote, in person or by proxy, for each share held on the record date. 

Votes cast by proxy or in person at the Meeting will be tabulated by the 
election inspector appointed for the Meeting and will determine whether or 
not a quorum is present.  The election inspector will treat abstentions as 
shares that are present and entitled to vote but not as voted for purposes of 
determining the approval of any matter submitted to the stockholders for a 
vote. Abstentions will have the same effect as negative votes.  If a broker 
indicates on the proxy that it does not have discretionary authority as to 
certain shares to vote on a particular matter, those shares will not be 
considered as present and entitled to vote with respect to that matter. 

Properly executed proxies will be voted in the manner directed by the 
stockholders.  If no direction is made, such proxies will be voted FOR the 
election of all nominees named under the caption "Election of Directors" as 
set forth herein as directors of the Company, FOR approval of the amendment 
to the Company's Amended and Restated 1996 Stock Option Plan and FOR the 
ratification of the selection of Price Waterhouse LLP as independent auditors 
for the fiscal year ending October 31, 1998.  Any proxy may be revoked by the 
stockholder at any time prior to the voting thereof by notice in writing to 
the Secretary of the Company, either prior to the Meeting (at the above 
address) or at the Meeting if the stockholder attends in person.  A later 
dated proxy will revoke a prior dated proxy.  As of the date of this Proxy 
Statement, the Board of Directors knows of no other business which will be 
presented for consideration at the Meeting.  If other proper matters are 
presented to the Meeting, however, it is the intention of the proxy holders 
named in the enclosed form of proxy to take such actions as shall be in 
accordance with their best judgment. 

The information contained in this Proxy Statement relating to the occupations 
and securities holdings of directors and officers of the Company and their 
transactions with the Company is based upon information received from each 
individual as of January 12, 1998.

                                       1
<PAGE>

                                ELECTION OF DIRECTORS

The nominees for election as a director of the Company are as follows:

<TABLE>
<CAPTION>

     NAME                    AGE      DIRECTOR SINCE
     <S>                     <C>          <C>
     Irwin J. Gruverman       64           1989

     L. Michael Cutrer        42           1989

     Larry Berkin             61           1996

     Dr. Allan M. Green       53           1996

     Michael C. Lee           47           1996

</TABLE>

Irwin J. Gruverman has been the Chairman and a director of the Company since 
December 31, 1989.  Mr. Gruverman has been a partner in G&G Diagnostics 
Limited Partnership, a venture capital limited partnership, since 1990.  Mr. 
Gruverman founded and has been the Chief Executive Officer and a director of 
Microfluidics International Corporation, a company that manufactures process 
devices for pharmaceutical and other manufacturing uses and conducts drug 
delivery testing, since 1982.  Mr. Gruverman founded and served as the 
Executive Vice President of New England Nuclear, a radioactive materials 
business, from 1961 to 1981.  Mr. Gruverman also serves as a director of 
InVitro International, Inc., Fiberchem International, Inc. and Endogen, Inc.

L. Michael Cutrer has been the President and Chief Executive Officer and a 
director of the Company since November 27, 1989.  Prior thereto, Mr. Cutrer 
was a Manager of Isotope Products Laboratory, Inc., a radioisotope 
manufacturing company, where he was responsible for industrial product 
manufacturing research and development from 1982 to 1989. 

Larry Berkin has been a director of the Company since May 1996 and  has been 
a certified public accountant with Berkin Accountancy Corp., a company he 
founded, since 1968.  His practice focuses primarily on management and 
taxation, including providing advice on operations, finances, investments, 
negotiations, real estate and taxes.

Dr. Allan M. Green has been a director of the Company since May 1996 and has 
been Vice President, Pharmaceutical/Biomedical Products for ML Strategies, 
Inc. since 1990.  ML Strategies, Inc. is the consulting affiliate of the law 
firm of Mintz Levin Cohn Ferris Glovsky and Popeo PC, of which Dr. Green is 
of counsel. Dr. Green has formerly served as President of the Biotechnology 
Data Group in Cambridge, Massachusetts and as a consultant to many major 
pharmaceutical companies and investors in the pharmaceutical industry.  Dr. 
Green is the author of many scientific papers in biochemistry and drug 
development.  Dr. Green is a director Neurochem, Inc.

Michael C. Lee has been a director of the Company since May 1996 and has been 
the President and Chief Executive Officer of East Coast Food Products, Inc., 
a wholesale food distributor, since 1976.  Mr. Lee is a director of Prime 
Spot Media, Inc.

The Board of Directors knows of no reason why any of the foregoing nominees 
will be unavailable to serve, but, in the event of any such unavailability, 
the proxies received will be voted for such substitute nominees as the Board 
of Directors may recommend.

                                       2
<PAGE>

                         HOLDINGS OF STOCKHOLDERS, DIRECTORS
                                AND EXECUTIVE OFFICERS

The following table sets forth information regarding the beneficial ownership 
of the Company's Common Stock as of February 16, 1998 by (i) each person who 
is known by the Company to own more than 5% of the Company's outstanding 
Common Stock, (ii) each of the Company's directors and nominees; and (iii) 
all existing directors and executive officers of the Company as a group:

<TABLE>
<CAPTION>

                                                                                  APPROXIMATE
                                                AMOUNT AND NATURE OF               PERCENT OF
 NAME AND ADDRESS (1)                           BENEFICIAL OWNERSHIP               OWNERSHIP

<S>                                             <C>                                  <C>

 Irwin J. Gruverman                                    296,500(2)                     6.9%

 L. Michael Cutrer                                     330,000(3)                     7.6%


 Larry Berkin                                          217,800(4)                     5.1%


 Dr. Allan M. Green                                     25,000(4)                       *

 Michael C. Lee                                        104,300(4)                     2.4%


 Mentor Corporation                                    250,000                        5.9%
 5425 Mollister Avenue
 Santa Barbara, CA 93111

 Tudor Investment Corporation                          300,000(5)                     7.0%
 One Liberty Plaza (51st Floor)
 New York, NY 10006

 All existing directors and executive                  978,600(2)(3)(4)              21.9%
 officers as a group
  (5 persons)

</TABLE>

_________________________

*Denotes less than 1%

(1)  Except where indicated, the address of each five percent stockholder is c/o
     the Company, 7435 Greenbush Avenue, North Hollywood, California.  
(2)  Includes 19,000 shares held in a fund of which the reporting person is
     general partner, 50,000 shares subject to outstanding options which are
     immediately exercisable and 5,000 shares subject to outstanding options
     which are exercisable March 28, 1998.  Excludes 20,000 shares owned by
     reporting person's spouse, as to which reporting person disclaims
     beneficial ownership.
(3)  Includes 80,000 shares subject to outstanding options which are immediately
     exercisable; also excludes 12,500 shares  owned by the reporting person's
     spouse and 8,375 shares subject to  vested options owned by the reporting
     person's spouse over which the reporting person disclaims beneficial
     ownership.
(4)  Includes 25,000 shares subject to outstanding options which are deemed
     exercisable.
(5)  Includes 284,700 shares held in investment funds to which the reporting
     person provides investment advice.  Also includes 15,300 shares in an
     investment fund which is under common control with the reporting person.

                                       3
<PAGE>

COMPENSATION OF DIRECTORS

All directors and officers of the Company are elected annually to serve for a 
term of one year and until their successors are elected and qualified.  All 
directors may be reimbursed for certain expenses incurred in connection with 
attending Board meetings.  Mr. Gruverman does not receive a salary as 
Chairman. 

Upon their election in 1996, Messrs. Berkin, Green and Lee were granted stock 
options exercisable for 40,000 shares of Common Stock at an exercise price 
equal to the fair market value of the Common Stock on the date of their 
election. Fifty percent (50%) of such stock options vested on the first 
anniversary date of the grant, with the remaining options vesting on the 
second anniversary date of the grant.  

If elected as directors of the Company at each Annual Meeting of Stockholders 
of the Company, Messrs. Gruverman, Berkin, Green and Lee shall each receive 
stock options exercisable for 10,000 shares of Common Stock with an exercise 
price equal to the fair market value of the Common Stock on the business day 
prior to the date they are elected.  Fifty percent (50%) of such stock 
options will vest on the first anniversary date of the grant of the stock 
options with the remaining stock options vesting on the second anniversary 
date of the grant of such options.

COMMITTEES; BOARD MEETINGS

The Board of Directors of the Company held four meetings during the fiscal 
year ended October 31, 1997, and the Board acted twice by unanimous written 
consent. The Company has an audit committee comprised of Messrs. Berkin 
(Chairman), Lee and Green, and a compensation committee comprised of Messrs. 
Gruverman (Chairman), Berkin, Lee and Green.  Neither the audit committee nor 
the compensation committee met during the fiscal year ended October 31, 1997. 

                                       4
<PAGE>

                                EXECUTIVE COMPENSATION

The following table sets forth the compensation paid to the Company's Chief 
Executive Officer for the fiscal year ended October 31, 1997.  No other 
officer of the Company received total annual salary and bonus in excess of 
$100,000 for such period.

                             SUMMARY COMPENSATION TABLE

<TABLE>
<CAPTION>
                                                                       LONG TERM
                                                                      COMPENSATION
                                   ANNUAL COMPENSATION                   AWARDS
                                   -------------------                   ------

                                                                      SECURITIES
     NAME AND                                          OTHER ANNUAL   UNDERLYING      ALL OTHER
PRINCIPAL POSITION      YEAR      SALARY      BONUS    COMPENSATION   OPTIONS (#)    COMPENSATION
- ------------------      ----      ------      -----    ------------   ----------     ------------
<S>                     <C>       <C>        <C>       <C>            <C>            <C>
L. Michael Cutrer       1997      $95,000       $0       $6,942(1)       100,000           $0
Chief Executive         1996      $91,404     $2,500         $0             0              $0
Officer                 1995      $75,673     $4,000         $0             0              $0
</TABLE>
_________________

(1)  Represents payment for Mr. Cutrer's accrued, but unused, vacation days.


STOCK OPTIONS

The following table sets forth certain information concerning individual 
grants of stock options made during the fiscal year ended October 31, 1997 to 
the Company's Chief Executive Officer under the Company's Amended and 
Restated 1996 Stock Plan.

                        OPTION/SAR GRANTS IN LAST FISCAL YEAR
<TABLE>
<CAPTION>

                    NUMBER OF  INDIVIDUAL
                   SECURITIES   GRANTS AS
                   UNDERLYING  % OF TOTAL
                    OPTIONS/  OPTIONS/SARS
                      SARS     GRANTED TO   EXERCISE OR
                     GRANTED  EMPLOYEES IN   BASE PRICE  EXPIRATION
        NAME           (#)     FISCAL YEAR   PER SHARE      DATE
<S>                <C>         <C>           <C>          <C>
L. Michael Cutrer  100,000(1)     72.1%       $1.05(2)     11/1/06
</TABLE>
_____________

(1)  Sixty percent (60%) of such options vested immediately upon grant, with the
     remainder vesting fifty percent (50%) per year over two years.
(2)  Such options were granted at the fair market value on  the date of grant
     determined pursuant to the Amended and Restated 1996 Stock Option Plan.

The following table sets forth certain information concerning the exercise of 
stock options during the fiscal year ended October 31, 1997 by the Company's 
Chief Executive Officer and the fiscal  year-ended value of unexercised 
options under the Company's Amended and Restated 1996 Stock Option Plan.

                                       5
<PAGE>

                 AGGREGATE OPTION EXERCISES IN LAST FISCAL YEAR
                        AND FISCAL YEAR END OPTION VALUES
<TABLE>
<CAPTION>
                                                  NUMBER OF
                                                 SECURITIES         VALUE OF
                                                 UNDERLYING       UNEXERCISED
                                                 UNEXERCISED      IN-THE-MONEY
                       SHARES                    OPTIONS AT        OPTIONS AT
                      ACQUIRED                    10/31/97        10/31/97(1)
                         ON         VALUE       EXERCISABLE/      EXERCISABLE/
        NAME          EXERCISE    REALIZED      UNEXERCISABLE    UNEXERCISABLE
<S>                   <C>         <C>           <C>              <C>
 L. Michael Cutrer        0           0         80,000/20,000     $1,516,000/
                                                                    $379,000
</TABLE>
_________________________

(1)  Calculated upon the difference between the exercise price and the fair
     market value at fiscal year-end.


                                 CERTAIN TRANSACTIONS

     On February 6, 1998, the Company entered into agreements with PracSys 
Corp., a privately held Massachusetts corporation ("PracSys"), pursuant to 
which (i) PracSys will manufacture and sell to the Company two particle 
accelerators (the "Systems") to be used in the production of certain 
isotopes, which will be utilized by the Company in connection with its new 
brachytherapy product line, and (ii) PracSys will operate the Systems to 
produce required isotopes for an initial 2-year period.  Irwin J. Gruverman, 
the Company's Chairman and a director and significant stockholder of both the 
Company and PracSys, was instrumental in introducing the parties but was not 
involved in the negotiation or approval of the agreements.  The agreements 
were negotiated between the parties on an arms-length basis. 

     The agreements call for total payments to PracSys of approximately $2.7 
million, which payments are required to be made upon the achievement of 
certain milestones set forth therein.   In addition, PracSys will receive a 
service fee and also will be entitled to a "royalty" on the Company's sales 
of products which incorporate isotopes produced using the Systems.  The 
Company and PracSys have also entered into an Exclusivity and Purchase 
Agreement pursuant to which the Company has been granted certain exclusivity 
rights with regard to the PracSys technology.  Pursuant to the Exclusivity 
Agreement, PracSys also issued to the Company an aggregate of 140,150 shares 
of PracSys Common Stock, which is equal to approximately 5% of PracSys total 
outstanding shares on a fully-diluted basis.  In addition, PracSys granted 
the Company a pre-emptive right in the event of certain pre-initial public 
offering private financing and a three-year warrant to purchase PracSys 
Common Stock equal to 5% of the number of shares of Common Stock issued in an 
initial public offering.  

PROPOSAL TO AMEND THE AMENDED AND RESTATED 1996 STOCK OPTION PLAN

The Board of Directors recommends that the stockholders approve the amendment 
of the Amended and Restated 1996 Stock Option Plan of the Company (the 
"Plan")(i) to increase the number of shares that may be issued pursuant to 
the Plan from 1,000,000 shares to 1,500,000 shares and (ii) to add provisions 
necessary to ensure that options granted under the Plan are not subject to 
the $1,000,000 limitation on deductibility of executive compensation under 
Section 162(m) of the Internal Revenue Code (the "Code").

Increase Number of Shares Authorized for Issuance Under the Plan

The Board of Directors believes that an increase in the number of shares 
authorized for issuance is necessary and desirable in order to maintain the 
efficacy of the Plan by allowing further grants to be made thereunder at the 
discretion of the Board of Directors. More specifically, the Board 
believes that an increase in the number of potentially issuable shares will 
allow management of the Company to continue to provide incentives to 
employees, directors and consultants of the Company, thus enhancing the value 
of the Company for the benefit of stockholders.

Compliance with Section 162(m) of the Code

To ensure compliance with Section 162(m) of the Code with respect to future 
grants of options under the Plan, the Company proposes (i) to limit the 
number of shares to which options may be granted to each executive officer 
whose compensation is required to be reported in the Company's annual proxy 
statement (an "Executive Officer") to 300,000 during any fiscal year during 
which such person serves as an Executive Officer and (ii) to provide for the 
administration of the Plan by a committee of "outside directors" appointed by 
the Board of Directors to administer the Plan (the "Stock Option Committee").

     Section 162(m) of the Code limits the deductible compensation paid to 
Executive Officers of publicly held corporations to $1,000,000. Any taxable 
compensation which is recognized by an Executive Officer upon (i) the 
exercise of a nonstatutory option or (ii) a disqualifying disposition of 
stock acquired under an incentive stock option, is subject to the limit. 
However, the limit will not apply if the options are granted under a 
stockholder-approved plan document which specifies the maximum number of 
option shares that can be granted to an Executive Officer during the 
corporation's tax year, provided that each grant is determined by a 
directors' committee which is comprised solely of "outside directors."

     The amount of compensation that would be subject to the $1,000,000 
deduction limit depends in part on the fair market value of the Company's 
stock at an indeterminable future date, thus the Company cannot be certain 
that any one Executive Officer's compensation will never exceed $1,000,000 in 
a given year. Accordingly, in order to comply with the provisions of Section 
162(m) of the Code and to protect the Company's deduction for all 
compensation to Executive Officers that is otherwise deductible, the Company 
is proposing an amendment to the Plan for stockholder approval which 
specifies the number of option shares which may be granted to an Executive 
Officer. The amendment limits option grants to 300,000 shares during any 
fiscal year in which a person serves as an Executive Officer. Furthermore, 
the Company is proposing that the Plan be amended to provide for 
administration by the Stock Option Committee. Having the Plan administered by 
the Stock Option Committee, as proposed, together with the limitation on the 
number of shares granted to Executive Officers, would allow the Company to 
comply with Section 162(m) of the Code and Rule 16b-3(b)(3)(i) of the 
Securities Exchange Act of 1934, as amended.

     The amendments, if approved by the stockholders, will allow the Company 
to retain a full compensation deduction with respect to future option grants 
under the Plan. The Plan was originally approved by the Board of Directors on 
April 1, 1996, received stockholder approval at the Company's 1996 Annual 
Meeting held on May 14, 1996, and received stockholder approval of an 
amendment thereto at the Company's 1997 Annual Meeting. The following summary 
of certain provisions of the Plan (as proposed to be amended) is subject to 
the complete text of the Plan attached to this Proxy Statement as Exhibit A.

                                    6
<PAGE>


TYPES OF AWARDS  

The Plan permits the granting of stock options, including incentive stock 
options.

AUTHORITY OF THE BOARD OF DIRECTORS

The Plan is currently administered by the Board of Directors of the Company.  
The Board has the authority to make grants and determine their terms, subject 
to the provisions of the Plan, and has the authority to interpret the 
provisions of the Plan, to adopt any rules, procedures and forms necessary 
for the operation and administration of the Plan, and to determine all 
questions relating to the eligibility and other rights of all persons under 
the Plan.  All directors, key employees of the Company, and certain 
consultants to the Company and any subsidiaries and affiliates are eligible 
to be participants.

SHARES SUBJECT TO PLAN

An aggregate of 1,000,000 shares of Common Stock are currently authorized for 
issuance pursuant to the Plan, such number of shares being subject to 
adjustment in the event of a merger, consolidation, stock dividend, split-up, 
combination, or exchange of shares, recapitalization or change in 
capitalization with respect to the shares of Common Stock.  The shares of 
stock deliverable under the Plan may consist in whole or in part of unissued 
shares or reacquired shares.  If a grant expires or is canceled, any shares 
which were not issued or fully vested under the grant at the time of 
expiration or cancellation will again be available for grants. Of the 
1,000,000 shares currently authorized, options for 537,250 shares have been 
granted as of the date of this Proxy Statement. 

STOCK OPTIONS

Options which are issuable under the Plan may be either "Incentive Stock 
Options," as defined in section 422 of the Internal Revenue Code, or options 
not intended to be so qualified ("Nonstatutory Options").  The Board may 
grant more than one option to a participant during the life of the Plan, and 
such option may be  in addition to an option or options previously granted; 
provided, however, that the aggregate fair market value of stock with respect 
to which Incentive Stock Options are exercisable for the first time by such 
individual during any calendar year (under all stock option plans of the 
Company and any subsidiaries) may not exceed $100,000.  All options (both 
Incentive Stock Options and Nonstatutory Options) are exercisable at no less 
than 100% of the fair market value of the shares on the date of grant, 
subject to anti-dilution provisions; provided, however, that if any Incentive 
Stock Option is granted to an individual who owns more than 10% of the total 
combined voting power of all classes of stock of the Company, actually or 
constructively under Section 425(d) of the Internal Revenue Code, such option 
is exercisable at 110% of the fair market value of the stock subject to the 
option.

No option is exercisable following three months after termination of employment
with the Company (or such shorter or longer period as the option may provide)
unless such termination of employment occurs by reason

                                       7
<PAGE>

of disability or death. In the event of the disability or death of an 
optionee while an employee of the Company or any subsidiary of the Company, 
the options or unexercisable portions thereof, to the extent exercisable on 
the date of disability or death, are exercisable at any time for a period not 
to exceed the expiration of one year from the date of disability or death (or 
such shorter period as the option may provide).  In no event, however, may an 
option be exercisable after the expiration of ten years from the date such 
option was granted (five years in the case of Incentive Stock Options granted 
to an optionee owning more than 10% of the voting power of stock of the 
Company as contemplated by Section 425(d) of the Internal Revenue Code), or 
beyond the term for which it was granted.

Except as provided otherwise by Board of Director resolution, payment for 
shares of Common Stock purchased upon exercise of an option granted under the 
Plan must be made in full at the time of such exercise, whether in cash, 
shares of the Company's Common Stock (valued at fair market value), by a note 
payable to the Company, or in a combination of cash, notes, and shares of 
stock. 

ADJUSTMENTS

If there is a merger, consolidation, stock dividend, split-up, combination or 
exchange of shares, recapitalization or change in capitalization with respect 
to the shares of Common Stock, or any other corporate action with respect to 
the shares of Common Stock which, in the opinion of the Board of Directors, 
adversely affects the relative value of a grant, the number of shares and the 
exercise price (in the case of an option) of any grant which is outstanding 
at the time of that event will be adjusted to the extent necessary to remedy 
the adverse effect on the grant's value.

FEDERAL INCOME TAX CONSEQUENCES

With respect to Nonstatutory Options, the difference between the option 
price and the fair market value of the stock on the date the option is 
exercised is taxable as ordinary income to the optionee and is deductible by 
the Company as compensation on such date except as described in the next 
paragraph.  Any gain or loss on the subsequent sale of such stock is eligible 
for capital gain or loss treatment by the optionee and will have no federal 
income tax consequences to the Company.

With respect to Nonstatutory Options, the Internal Revenue Code provides 
that so long as the sale of the stock at a profit could subject a person to 
suit under Section 16(b) of the Securities Exchange Act of 1934, the stock 
will be subject to a substantial risk of forfeiture.  Accordingly, unless the 
election provided by Section 83(b) of the Internal Revenue Code is made, upon 
exercise of a Nonstatutory Option by an officer or director or 10% 
stockholder of the Company, no income will be recognized (assuming no sale is 
made by the optionee during the next six months), nor will the capital gain 
holding period begin to run or the Company be allowed a deduction, until the 
six month period prescribed by Section 16(b) has lapsed.  The income to the 
optionee and deduction to the Company will be determined on the basis of the 
fair market value of the stock on the date of lapse.

An exchange of Common Stock in payment of the option price in the case of a 
Nonstatutory Option is considered a tax-free exchange by the optionee to the 
extent of a like number of new shares, with the new shares retaining the 
basis and holding period of the old shares.  The fair market value of any 
additional shares transferred to the optionee (representing the excess of the 
fair market value of all of the new shares over the fair market value of all 
of the old shares) will constitute ordinary income to the optionee and be 
deductible by the Company.  This amount then becomes the optionee's basis in 
such shares.

                                       8
<PAGE>

With respect to Incentive Stock Options, if the optionee does not make a 
disqualifying disposition of stock acquired on exercise of such option, no 
income for federal income tax purposes will result to such optionee upon the 
granting or exercise of the option (except that the amount by which the fair 
market value of the stock at time of exercise exceeds the option price will 
be a tax preference item under the expanded alternative minimum tax), and in 
the event of any sale thereafter any amount realized in excess of his cost 
will be taxed as long term capital gain and any loss sustained will be long 
term capital loss.  In such case, the Company will not be entitled to a 
deduction for federal income tax purposes in connection with the issuance or 
exercise of the option. Generally, a disqualifying disposition will occur if 
the optionee makes a disposition of such shares within two years from the 
date of the granting of the option or within one year after the transfer of 
such shares to him.  If a disqualifying disposition is made, the difference 
between the option price and the lesser of (i) the fair market value of the 
stock at the time the option is exercised or (ii) the amount realized upon 
disposition of the stock, will be treated as ordinary income to the optionee 
at the time of disposition and will be allowed as a deduction to the Company.

An exchange of Common Stock in payment of the option price in the case of an 
Incentive Stock Option, if the exchange is not a disqualifying disposition of 
the stock exchanged, is considered to be tax-free.  Under Internal Revenue 
Service proposed regulations, a number of shares received upon exercise equal 
to the number of shares exchanged will have a basis equal to the basis of the 
shares exchanged and the remaining shares received will have a zero basis.

A portion of the excess of the amount deductible by the Company over the 
value of options when issued may be subject to the alternative minimum tax 
imposed on corporations.

The described tax consequences are based on current laws, regulations and 
interpretations thereof, all of which are subject to change.  In addition, 
the discussion is limited to federal income taxes and does not attempt to 
describe state and local tax effects which may accrue to participants or the 
Company.

The following table sets forth the number of stock options issued during the 
fiscal year.  Awards to the Company's Chief-Executive Officer and to 
non-executive officer employees remain at the discretion of the Board of 
Directors.

<TABLE>
<CAPTION>
                                                 NUMBER OF SHARES
          NAME OF POSITION                   UNDERLYING OPTIONS GRANTED
          <S>                                       <C>
          Chief Executive Officer                     100,000
          Executive Group                             100,000
          Non-Executive Director Group                100,000
          Non-Executive Officer Employee Group         50,500
</TABLE>
                                       9
<PAGE>

VOTE REQUIRED

The affirmative vote of a majority of outstanding shares of Common Stock at 
the Meeting at which a quorum is present, is necessary to approve this 
proposal to amend the Company's Amended and Restated 1996 Stock Option Plan.

THE BOARD RECOMMENDS THAT THE STOCKHOLDERS VOTE IN FAVOR OF THE PROPOSAL TO 
AMEND THE AMENDED AND RESTATED 1996 STOCK OPTION PLAN.


                     PROPOSAL TO RATIFY SELECTION OF INDEPENDENT
                             CERTIFIED PUBLIC ACCOUNTANTS

The firm of Price Waterhouse LLP has audited the books and records of the 
Company since October 1993 and the Board of Directors desires to continue the 
services of this firm for the current fiscal year ending October 31, 1998. 
Accordingly, the Board of Directors will recommend at the Meeting that the 
stockholders ratify the appointment of the firm of Price Waterhouse LLP to 
audit the accounts of the Company for the current fiscal year. 
Representatives of that firm are expected to be present at the Meeting with 
the opportunity to make a statement if they desire to do so and are expected 
to be available to respond to appropriate questions.

THE BOARD RECOMMENDS THAT STOCKHOLDERS VOTE IN FAVOR OF RATIFICATION OF THE 
SELECTION OF PRICE WATERHOUSE LLP.

                         COMPLIANCE WITH SECTION 16(a) OF THE
                           SECURITIES EXCHANGE ACT OF 1934

The Company is required to report to its stockholders those directors, 
officers and owners of more than 10% of any class of the Company's equity 
securities registered pursuant to Section 12 of the Securities Exchange Act 
of 1934, as amended (the "Exchange Act"), who fail to timely file reports of 
beneficial ownership and changes in beneficial ownership, as required by 
Section 16(a) of the Exchange Act.  Upon a review of these reports, the 
Company believes that all reports were filed on a timely basis.  

                                    MISCELLANEOUS

The Company's Annual Report for the fiscal year ended October 31, 1997 is 
being mailed to stockholders contemporaneously with this Proxy Statement.

COST OF SOLICITATION

All expenses incurred in the solicitation of proxies will be borne by the 
Company.  In addition to the use of the mails, proxies may be solicited on 
behalf of the Company by directors, officers and employees of the Company or 
by telephone or telecopy.  The Company will reimburse brokers and others 
holding Common Stock as nominees for their expenses in sending proxy material 
to the beneficial owners of such Common Stock and obtaining their proxies.

                                       10
<PAGE>

PROPOSALS OF SECURITY HOLDERS

Proposals of security holders intended to be presented at the 1999 Annual
Meeting must be received by the Company for inclusion in the Company's Proxy
Statement and form of proxy relating to that meeting no later than November 6,
1998.

                                        By order of the Board of Directors.


                                        L. Michael Cutrer
                                        PRESIDENT
Dated: March 6, 1998

                                       11
<PAGE>

                                     EXHIBIT A

                          NORTH AMERICAN SCIENTIFIC, INC.

                               AMENDED AND RESTATED 
                               1996 STOCK OPTION PLAN
                            (AS PROPOSED TO BE AMENDED)

1.   PURPOSE OF THE PLAN.  Under this 1996 Stock Option Plan (the "Plan") of 
     North American Scientific, Inc. (the "Company") options may be granted 
     to eligible employees, directors and consultants to purchase shares of 
     the Company's capital stock.  The Plan is designed to enable the Company 
     to attract, retain, and motivate its employees, directors and 
     consultants by providing for or increasing the proprietary interests of 
     such individuals in the Company.  The Plan provides for options which 
     qualify as incentive stock options ("Incentive Options") under Section 
     422 of the Internal Revenue Code of 1986, as amended (the "Code"), as 
     well as options which do not so qualify ("Nonstatutory Options").  Any 
     option granted under this Plan shall be clearly identified as either an 
     Incentive Option or a Nonstatutory Option.

2.   STOCK SUBJECT TO PLAN. The aggregate number of shares which may be 
     issued under options is 1,500,000 shares of the Company's Common Stock, 
     $0.01 par value ("Common Stock"), subject to the adjustments hereinafter 
     provided.  Such number of shares shall be reserved by the Company for 
     options granted under this Plan. The shares which may be issued or 
     delivered under the Plan may be either authorized but unissued shares or 
     treasury shares or partly each.  Shares of stock subject to the 
     unexercised portions of any options granted under this Plan which expire 
     or terminate or are canceled may again be subject to options under the 
     Plan. 

3.   ELIGIBILITY.  The employees eligible to be considered for the grant of 
     Incentive Options hereunder are all employees (including directors) 
     regularly employed by the Company.  All such employees and all 
     nonemployed directors or consultants to the Company shall also be 
     eligible to receive Nonstatutory Options hereunder.  The Committee 
     referred to in Section 13 will designate, from among the eligible 
     employees, those who will be granted Options and will specify: (i) the 
     number of shares of the Company's common stock each such employee will 
     be entitled to purchase pursuant to the option; and (ii) the nature of 
     an Option as an Incentive Option, a Nonstatutory Option or partly each 
     type of Option.  The Committee may make such grants at any time and in 
     any amounts that it, in its discretion, may designate, subject to the 
     other relevant limitations set out in this Plan.

          The number of Option shares granted in a fiscal year to each 
     executive officer whose compensation is subject to reporting on the 
     Company's annual proxy statement (an "Executive Officer") shall not exceed
     300,000 shares for any fiscal year during which he or she serves as an 
     Executive Officer.

4.   $100,000 INCENTIVE OPTION EXERCISE LIMITATION.  The aggregate fair 
     market value of the stock for which Incentive Options granted to any one 
     eligible employee under this Plan and under all incentive stock option 
     plans of the Company, its parent(s) and any subsidiaries, may by their 
     terms first become exercisable during any calendar year shall not exceed 
     $100,000, determining fair market value of the stock subject to any 
     option as of the time that option is granted. If the date on which one 
     or more Incentive Options could be first exercised would be accelerated 
     pursuant to any other provision of the Plan or any stock option 
     agreement referred to in Section 10, or an amendment thereto, and the 
     acceleration of such exercise date would result in a violation of the 
     restriction set forth in the preceding sentence, then notwithstanding 
     any such other provision the exercise date of such Incentive Options 
     shall be accelerated only to the extent, if any, that is permitted under 
     Section 422 of the Code and the exercise date of the Incentive Options 
     with the lowest option prices shall be accelerated first. Any exercise 
     date which cannot be accelerated without violating the $100,000

<PAGE>

     restriction of this section shall nevertheless be accelerated, and the 
     portion of the option becoming exercisable thereby shall be treated as a 
     nonstatutory option.

5.   OPTION PRICE.  The purchase price at which each stock option may be 
     exercised (the "Option Price") shall be such price as the Board of 
     Directors, in its discretion, shall determine, and, in the case of 
     Incentive Options, shall not be less than one hundred percent (100%) of 
     the fair market value per share of the Common Stock covered by the 
     Incentive Option on the date of grant, except that in the case of an 
     Incentive Option granted to an employee who, immediately prior to such 
     grant, owns stock possessing more than ten percent (10%) of the total 
     combined voting power of all classes of stock of the Company or any 
     subsidiary (a "Ten Percent Employee"), the Option Price shall not be 
     less than one hundred ten percent (110%) of such fair market value on 
     the date of grant.  For purposes of this Section 5, the fair market 
     value of the Common Stock shall be determined as provided in Section 11. 
     For purposes of this Section 5, an individual (a) shall be considered 
     as owning not only shares of the Common Stock owned individually but 
     also all shares that are at the time owned, directly or indirectly, by 
     or for the spouse, ancestors, lineal descendants and brothers and 
     sisters (whether by the whole or half blood) of such individual, and (b) 
     shall be considered as owning proportionately any shares owned, directly 
     or indirectly by or for any corporation, partnership, estate or trust in 
     which such individual shall be a shareholder, partner or beneficiary.

6.   EXERCISE OF OPTION.  The option agreement may provide for partial 
     exercise in installments.  Exercisable options may be exercisable in 
     full or in part.  The period of time in which an option may be exercised 
     shall be the period designated in the option.  In the case of an 
     Incentive Option such period shall not exceed ten (10) years from the 
     date the option is granted and with respect to a Ten Percent Employee, 
     such period of time shall not exceed five (5) years from the date the 
     Incentive Option is granted.  No Nonstatutory Option shall be 
     exercisable after the expiration of ten years from the date of grant.  
     An option to the extent exercisable at any time may be exercised in 
     whole or in part.

7.   PAYMENT OF OPTION PRICE.  Payment for stock purchased under any exercise 
     of an option granted under this Plan shall be made in full in cash 
     concurrently with such exercise.  Alternatively, such payment may be 
     made in whole or in part with shares of the same class of stock as that 
     then subject to the option, delivered in lieu of cash concurrently with 
     such exercise, the shares so delivered to be valued on the basis of the 
     fair market value of stock (determined in a manner provided in Section 
     11 hereof) provided that the Company is not then prohibited from 
     purchasing or acquiring shares of such stock.

          Notwithstanding the foregoing, the Company shall not be obligated to
     accept payment of the exercise price pursuant to this Section 7 unless the
     stock tendered as payment for the exercise price has been held by the
     optionee for at least six months.  The Company also has the discretion to
     refuse any other method of payment that would cause the Plan or the option
     agreements issued thereunder to be treated for accounting purposes as
     creating stock appreciation rights or other "variable stock plan"
     characteristics which would cause the Company to recognize a charge to
     earnings.

8.   NONTRANSFERABILITY.  Any option granted under this Plan shall by its 
     terms be nontransferable by the optionee other than by will or the laws 
     of descent and distribution and is exercisable during the optionee's 
     lifetime only by him or by his guardian or legal representative.

9.   TERMINATION OF OPTION.  In the case of Incentive Options:

<PAGE>

     a.  If the employment or other service to the Company or a subsidiary of 
         an optionee (whether employee, nonemployed director, or consultant) 
         who is not disabled within the meaning of Section 422(c)(6) of the 
         Code (a "Disabled Optionee") is terminated without cause, quits or 
         retires under any retirement plan of the Company or a subsidiary, 
         any then outstanding and exercisable stock option held by such an 
         optionee shall be exercisable, in  accordance with the provisions of 
         the stock option agreement referred to in Section 10, by such 
         optionee at any time prior to the expiration date of such stock 
         option or within three months after the date of termination of 
         employment or service, whichever is the shorter period;

     b.  If the employment of an optionee who is a Disabled Optionee is 
         terminated without cause or if the service of a nonemployed director 
         or consultant terminates because such individual becomes a Disabled 
         Optionee, any then outstanding and exercisable stock option held by 
         such an optionee shall be exercisable, in accordance with the 
         provisions of the stock option agreement referred to in Section 10, 
         by such an optionee at any time prior to the expiration date of such 
         stock option or within one year after the date of such termination 
         of employment or service, whichever is the shorter period;

     c.  Following the death of an optionee during employment or of a 
         nonemployed director or consultant while serving as a director or 
         consultant of the Company or a subsidiary, any outstanding and 
         exercisable stock option held by such an optionee at the time of 
         death shall be exercisable, in accordance with the provisions of the 
         stock option agreement referred to in Section 10, by the person or 
         persons entitled to do so under the will of the optionee, or, if the 
         optionee shall fail to make testamentary disposition of the stock 
         option or shall die intestate, by the legal representative of the 
         optionee at any time prior to the expiration date of such stock 
         option or within one year after the date of death, whichever is the 
         shorter period.

     With respect to Nonstatutory Options:

          The Committee may specify in the option agreement what restrictions
     will apply in the event of termination of employment. 

          For all options issued hereunder, if the Company terminates the
     employment of an optionee for cause, all outstanding stock options held by
     the optionee at the time of such termination shall automatically terminate
     unless the Board of Directors notifies the optionee that his options will
     not terminate.  A termination "for cause" shall be defined under each
     written option agreement issued pursuant to Section 10.

          Whether termination of employment or other service is a termination
     "for cause" and whether an optionee is disabled within the meaning of
     Section 422(c)(6) of the Code shall be determined in each case, in its
     discretion, by the Board of Directors and any such determination by the
     Board of Directors shall be final and binding.

10.  WRITTEN OPTION AGREEMENT.  All options granted pursuant to the Plan 
     shall be evidenced by written option agreements.  Such option agreements 
     shall comply with and be subject to all of the terms, conditions, and 
     limitations set forth in this Plan and such further provisions, not 
     inconsistent with this Plan, as the Board of Directors shall deem 
     appropriate.

11.  DETERMINATION OF FAIR MARKET VALUE.  Fair market value of the Common 
     Stock shall be the closing price of the Common Stock on the NASDAQ 

<PAGE>

     National Market (or such successor exchange or automated quotation 
     system upon which the Common Stock becomes listed) on the day prior to 
     the grant.

12.  ADJUSTMENTS.  If the outstanding shares of stock of the class then 
     subject to this Plan are increased or decreased, or are changed into or 
     exchanged for a different number or kind of shares or securities, as a 
     result of one or more reorganizations, recapitalization, stock splits, 
     reverse stock splits, stock dividends or the like, appropriate 
     adjustments shall be made in the number and/or kind of shares or 
     securities for which options may thereafter be granted under this Plan 
     and for which options then outstanding under this Plan may thereafter be 
     exercised.  The Board of Directors shall make such adjustments as it may 
     deem fair, just and equitable to prevent substantial dilution or 
     enlargement of the rights granted to or available for optionees.  No 
     adjustment provided for in this Section 12 shall require the Company to 
     issue or sell a fraction of a share or other security.

          If any such adjustment provided for in this Section 12 requires the
     approval of stockholders in order to enable the Company to grant Incentive
     Options, then no such adjustment shall be made without the required
     stockholder approval.  Notwithstanding the foregoing, in the case of
     Incentive Options, if the effect of any such adjustment would be to cause
     the stock option to fail to continue to qualify as an Incentive Option or
     to cause a modification, extension or renewal of such stock option within
     the meaning of Section 424 of the Code, the Board of Directors  may elect
     that such adjustment not be made but rather shall use reasonable efforts to
     effect such other adjustment of each then outstanding stock option as the
     Board of Directors, in its sole discretion, shall deem equitable and which
     will not result in any disqualification, modification, extension or renewal
     (within the meaning of Section 424 of the Code) of such Incentive Option.

13.  ADMINISTRATION. The Plan shall be administered by a committee appointed 
     by the Board of Directors of the Company (the "Committee") which shall 
     be comprised of not less than two members who are "Non-Employee Directors"
     as defined in Rule 16b-3(b)(3)(i), promulgated under the Securities 
     Exchange Act of 1934, as amended and who shall each also qualify as an 
     "outside director" for purposes of Section 162(m) of the Code.  An 
     individual shall not be a member of the Committee if he has received any 
     options under this Plan during the one year period preceding his proposed 
     appointment to the Committee.  Members of the Committee shall not be 
     eligible to receive options granted hereunder at any time.  Any vacancy on 
     the Committee shall be filled by appointment by the Board of Directors.

     The Committee may interpret the Plan, prescribe, amend and rescind any
     rules or regulations necessary or appropriate for the administration of the
     Plan, and make all  determinations, in its discretion, as to which eligible
     employees will receive options, the number of shares subject to the options
     and the exercise price.  The Committee may make such other determination
     and take such other action it deems necessary or advisable.  Without
     limiting the generality of the foregoing, the Committee may, in its
     discretion, treat all or any portion of any period during which a
     participant is on military or other approved leave of absence from the
     Company or a subsidiary as a period of employment of such participant by
     the Company or such subsidiary, as the case may be, for purposes of accrual
     of his rights under his awards; provided, however, that no Incentive Option
     may be awarded to an employee while he is on leave of absence.

14.  LIMITATIONS RESPECTING INCENTIVE OPTIONS.  It is the intent of the 
     Company to conform strictly to the requirements of Code Section 422 with 
     regard to Incentive Options granted pursuant to this Plan.  Therefore, 
     notwithstanding any other provision of this Plan, nothing herein with 
     regard to Incentive Options shall contravene any requirement set forth 

<PAGE>

     in Code Section 422 and if inconsistent provisions are otherwise found 
     herein, they shall be deemed void and unenforceable or automatically 
     amended to conform, as the case may be.

15.  RIGHTS AS A STOCKHOLDER.  An optionee, or his executor, administrator or 
     legatee if he be deceased, shall have no rights as a stockholder with 
     respect to any stock covered by his option under the date of issuance of 
     the stock certificate to him or such stock after receipt of the 
     consideration in full set forth in the option agreement or as may be 
     approved by the Board of Directors.  Except as provided in Section 12 
     hereof, no adjustments shall be made for dividends, whether ordinary or 
     extraordinary, whether in cash, securities, or other property, for 
     distributions in which the record date is prior to the date for which 
     the stock certificate is issued.

16.  MODIFICATION, EXTENSION AND RENEWAL.  Subject to the conditions of, and 
     within the limitations prescribed in, Section 14, hereof, the Board of 
     Directors may modify, extend or renew options which are outstanding as 
     granted under the Plan if otherwise consistent herewith.  
     Notwithstanding the foregoing, no modification shall, without the prior 
     written consent of the optionee, alter, impair or waive any rights or 
     obligations of any option theretofore granted under the Plan.

17.  INVESTMENT PURPOSES, ETC.  Prior to the issuance or delivery of any 
     shares of the common stock under the Plan, the person exercising the 
     stock option may be required to (a) represent and warrant that the 
     shares of the Common Stock to be acquired upon exercise of the stock 
     option are being acquired for investment for the account of such person 
     and not with a view to resale or other distribution thereof, (b) 
     represent and warrant that such person will not, directly or indirectly, 
     transfer, sell, assign, pledge, hypothecate or otherwise dispose of any 
     such shares unless the transfer, sale, assignment, pledge, hypothecation 
     or other disposition of the shares is pursuant to effective 
     registrations under the 1933 Act and applicable state or foreign 
     securities laws or pursuant to appropriate exemptions from any such 
     registrations, (c) execute such further documents as may be reasonably 
     required by the Board of Directors upon exercise of the option or any 
     part thereof, including but not limited to stock transfer restrictions.  
     The certificate or certificates representing the shares of the common 
     stock to be issued or delivered upon exercise of a stock option may bear 
     a legend evidencing the foregoing and other legends required by any 
     applicable securities laws.  Furthermore, nothing herein or any option 
     granted hereunder shall require the Company or any subsidiary to issue 
     any stock upon exercise of any option if the issuance would, in the 
     opinion of counsel for the Company, constitute a violation of the 
     Securities Act of 1933, as amended, the California securities laws, or 
     any other applicable rule or regulation then in effect.

18.  NO RIGHT TO CONTINUED EMPLOYMENT.  This Plan, and any option granted 
     under this Plan, shall not confer upon any optionee any right with 
     respect to continued employment by or service to the Company or any 
     subsidiary, nor shall they alter, modify, limit or interfere with any 
     right or privilege of the Company or any subsidiary under any employment 
     or service contract heretofore or hereinafter executed with any 
     optionee, including the right to terminate any optionee's employment, 
     directorship, or consultancy service, at any time for or without cause.

19.  DISPOSITION OF INCENTIVE OPTION SHARES.  Except (a) as provided in 
     options to the Company and other holders of the stock contained in stock 
     transfer restriction agreements to which the Company is a party, or (b) 
     in connection with reorganizations or other transactions described in 
     Section 12 hereof, no stock acquired by the exercise of an Incentive 
     Option granted under the Plan shall be transferable, otherwise than by 
     will or the laws of descent and distribution, within two (2) years after 
     the date the option was granted or within one (1) year after the 
     transfer of such share of stock to the optionee pursuant to the exercise 
     of the option.  Each certificate representing the acquired shares may 
     bear a legend to this effect.

<PAGE>

20.  COMPLIANCE WITH OTHER LAWS AND REGULATIONS.  The Plan, the options 
     granted hereunder and the obligation of the Company to sell and deliver 
     stock under such options, shall be subject to all applicable federal and 
     state laws, rules, regulations and to such approvals by any government 
     or regulatory authority or investigative agency as may be required.  The 
     Company shall not be required to issue or deliver any certificates for 
     shares of stock prior to (a) the listing of any such stock to be 
     acquired pursuant to the exercise of any option on any stock exchange on 
     which the stock may then be listed, and (b) the compliance with any 
     registration requirements or qualification of such shares under any 
     federal or state securities laws, or obtaining any ruling or waiver from 
     any government body which the Company or it subsidiaries shall, in their 
     sole discretion, determine to be necessary or advisable, or which, in 
     the opinion of counsel to the Company or its subsidiaries, is otherwise 
     required.

21.  CORPORATE REORGANIZATIONS.  Upon the dissolution or liquidation of the 
     Company, or upon a reorganization, merger or consolidation of the 
     Company as a result of which the outstanding securities of the class 
     then subject to options hereunder are changed into or exchanged for cash 
     or property or securities not of the Company's issue, or upon a sale of 
     substantially all the property of the Company to, or the acquisition of 
     stock representing more than eighty percent (80%) of the voting power of 
     the stock of  the Company then outstanding by another corporation or 
     person, the Plan shall terminate, and all options theretofore granted 
     hereunder shall terminate, unless provision be made in writing in 
     connection with such transaction for the continuance of the Plan and/or 
     for the assumption of options theretofore granted, or the substitution 
     for such options of options covering the stock of a successor employer 
     corporation, or a parent or a subsidiary thereof, with appropriate 
     adjustments as to the number and kind of shares and prices, in which 
     event the Plan and options theretofore granted shall continue in the 
     manner and under the terms so provided.  If the Plan and unexercised 
     options shall terminate pursuant to the foregoing sentence, all persons 
     entitled to exercise any unexercised portions of options then 
     outstanding shall have the right, at such time prior to the consummation 
     of the transaction causing such termination as the Company shall 
     designate, to exercise the unexercised portions of their options, 
     including the portions thereof which would, but for this Section 21, not 
     yet be exercisable.

22.  WITHHOLDING.  If, upon exercise of any Nonstatutory Option (or any 
     Incentive Option which is treated as a Nonstatutory Option because it 
     fails to meet the requirements set forth herein for Incentive Options), 
     the optionee fails to tender payment to the Company for any federal 
     income tax withholding, the Board of Directors shall withhold from the 
     optionee sufficient shares or fractional shares having a fair market 
     value (determined under Section 11) equal to any amount which the 
     Company is required to withhold under the Code. 

23.  AMENDMENT AND TERMINATION.  The Company may alter, amend, suspend or 
     terminate this Plan, provided that no such action shall deprive an 
     optionee, without his consent, of any option granted to the optionee 
     pursuant to this Plan or of any of such optionee's rights under such 
     option.  Except as herein provided no such action of the Company, unless 
     approved by the shareholders of the Company within twelve months prior 
     or twelve months after such action, may:

     a.  increase the maximum number of shares for which options granted 
         under this plan may be exercised;

     b.  reduce the minimum permissible exercise price;

     c.  extend the ten-year duration of this Plan set forth herein; or

<PAGE>

     d.  alter the class of employees eligible to receive options under the 
         Plan.

24.  PLAN DATE AND DURATION.  The Plan shall take effect on the date it is 
     adopted by the Board of Directors of the Company.  Options may not be 
     granted under this Plan more than ten years after the date of the 
     adoption of this Plan, or of shareholder approval thereof, whichever is 
     earlier.

25.  GOVERNING LAW.  All questions arising with respect to the provisions of 
     the Plan shall be determined by application of the laws of the state of 
     Delaware except to the extent that Delaware laws are preempted by any 
     federal statute, regulation, judgment or court order, including but not 
     limited to, the Code.

<PAGE>

                        NORTH AMERICAN SCIENTIFIC, INC.
                            7435 GREENBUSH AVENUE
                          NORTH HOLLYWOOD, CA 91605


              PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned hereby appoints L. Michael Cutrer and Irwin J. 
Gruverman, and each of them, attorney and proxy to represent the undersigned 
at the 1998 Annual Meeting of Stockholders of North American Scientific, Inc. 
(the "Company") to be held at the Holiday Inn located at 150 East Angeleno, 
Burbank, California at 10:00 a.m. local time, on Friday, April 3, 1998, or at 
any adjournment thereof, with all power which the undersigned would possess 
if personally present, and to vote all shares of stock of the Company which 
the undersigned may be entitled to vote at said Meeting as follows:


1. ELECTION OF DIRECTORS
   FOR all nominees listed below (unless name of    WITHHOLD AUTHORITY  /  /
   nominee is crossed out)  /  /

   Irwin J. Gruverman      L. Michael Cutrer      Larry Berkin  

   Dr. Allan M. Green     Michael C. Lee

2. PROPOSAL TO AMEND THE AMENDED AND RESTATED 1996 STOCK OPTION PLAN
   /  / FOR   /  / AGAINST   /  / ABSTAIN

3. PROPOSAL TO RATIFY THE SELECTION OF PRICE WATERHOUSE LLP AS INDEPENDENT
   AUDITORS
   /  / FOR   /  / AGAINST   /  / ABSTAIN

4. IN THEIR DISCRETION, ON SUCH OTHER MATTERS AS MAY PROPERLY COME BEFORE THE
   MEETING (which the Board of Directors does not know of prior to March 6, 
   1998)

   Management recommends your vote FOR all proposals.

<PAGE>

     THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED 
HEREIN BY THE UNDERSIGNED STOCKHOLDER.  IF NO DIRECTION IS MADE, THIS PROXY 
WILL BE VOTED FOR THE ELECTION OF ALL NOMINEES FOR DIRECTOR, FOR APPROVAL OF 
THE PROPOSED AMENDMENT TO THE AMENDED AND RESTATED 1996 STOCK OPTION PLAN AND 
FOR THE RATIFICATION OF THE SELECTION OF PRICE WATERHOUSE LLP AS INDEPENDENT 
AUDITORS, AND WILL CONFER THE AUTHORITY SET FORTH IN PARAGRAPH 4.

     Receipt is hereby acknowledged of the Notice of the Meeting and Proxy 
Statement dated March 6, 1998, as well as a copy of the Company's Annual 
Report for the fiscal year ended October 31, 1997.

Dated: _______, 1998.


                              ------------------------------------------

                              ------------------------------------------
                              (Signature of stockholder)

                              WHEN SIGNING AS ATTORNEY, EXECUTOR, 
                              ADMINISTRATOR, TRUSTEE OR GUARDIAN, PLEASE GIVE 
                              TITLE. EACH JOINT OWNER IS REQUESTED TO SIGN. 
                              IF A CORPORATION OR PARTNERSHIP, PLEASE SIGN BY 
                              AN AUTHORIZED OFFICER OR PARTNER. PLEASE SIGN 
                              IN THE SAME MANNER AS YOUR CERTIFICATE(S) IS 
                              (ARE) REGISTERED.

  PLEASE COMPLETE, DATE, SIGN AND RETURN this proxy in the envelope provided.



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