SYNTEX CORP
SC 14D1/A, 1994-05-16
PHARMACEUTICAL PREPARATIONS
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                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D. C. 20549

                                ---------------


                                AMENDMENT NO. 1
                                      TO
                                SCHEDULE 14D-1
                  Tender Offer Statement Pursuant to Section
                14(d)(1) of the Securities Exchange Act of 1934

                              Syntex Corporation
                           (Name of Subject Company)

                           Roche Capital Corporation
                                   (Bidder)

                    Common Stock, Par Value $1.00 Per Share
                        (Title of Class of Securities)

                                   87161610
                     (CUSIP Number of Class of Securities)

                               Dr. Felix Amrein
                             c/o Roche Holding Ltd
                            Grenzacherstrasse 124
                                 CH-4002 Basel
                                  Switzerland

                         Telephone: (41) (61) 688-1111
  (Name, Address and Telephone Number of Person Authorized to Receive Notices
                    and Communications on Behalf of Bidder)

                                ---------------

                                  Copies to:

                               Peter R. Douglas
                             Davis Polk & Wardwell
                             450 Lexington Avenue
                           New York, New York  10017
                          Telephone:  (212) 450-4000

                                  May 6, 1994

                                ---------------

     Date Tender Offer First Published, Sent or Given to Security Holders
==============================================================================


CUSIP No.  871 616 10


1   NAME OF REPORTING PERSON
    S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
        Roche Capital Corporation
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                          (a)  [ ]
                                                          (b)  [ ]
3   SEC USE ONLY
4   SOURCE OF FUNDS*
        AF
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
    TO ITEMS 2 (e) OR 2 (f) [ ]

6   CITIZENSHIP OR PLACE OF ORGANIZATION
        Panama
7   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
        0
8   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (7) EXCLUDES CERTAIN SHARES*  [ ]
9   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (7)
        N/A
10  TYPE OF REPORTING PERSON*
        CO


     This Amendment No. 1 amends and supplements the Tender Offer Statement
on Schedule 14D-1 (the "Statement")  dated May 6, 1994 filed by Roche Capital
Corporation, a Panama corporation (the "Bidder") and a wholly owned subsidiary
of Sapac Corporation Limited, a non-resident Canadian corporation ("Holding"),
which, in turn, is a wholly owned subsidiary of Roche Holding Ltd, a
Switzerland corporation ("Parent"), relating to the Bidder's offer to purchase
all outstanding shares of Common Stock, $1.00 par value (the "Shares") of
Syntex Corporation (the "Company"), at $24.00 per Share, net to the seller in
cash, upon the terms and subject to the conditions set forth in the Offer to
Purchase and the related Letter of Transmittal, copies of which are attached
as Exhibits (a)(1)  and (a)(2) to the Statement (which are herein referred to
as the "Offer"). Capitalized terms not separately defined herein shall have
the meanings specified in the Statement.

Item 9.  Financial Statements of Certain Bidders.


     The financial data relating to the Roche Group is hereby amended to
include certain financial information for the fiscal year ended December 31,
1993, released by Parent on May 10, 1994.

     The following selected financial data relating to the Roche Group has
been taken or derived from the financial statements contained in the English
translation of Parent's Annual Report to Stockholders for the year ended
December 31, 1993 ("Parent's 1993 Annual Report"), released on May 10, 1994.
More comprehensive financial information (including the notes to the Roche
Group's financial statements) is included in Parent's 1993 Annual Report and
the financial data set forth below is qualified in its entirety by reference
to such report including the financial statements and related notes contained
therein.  This document may be obtained from Parent at the address listed in
the Statement. The data contained in the consolidated statement of income and
consolidated balance sheet presented below was prepared in accordance with the
accounting principles formulated by the International Accounting Standards
Committee. A comparison of certain aspects of these principles with United
States generally accepted accounting principles is set forth in Exhibit (a)(1)
to the Statement at Item 8; the financial information set forth below should
be read in conjunction with that comparison.

     The consolidated financial statements of the Roche Group are published in
Swiss francs ("Sfr.").  The following table sets forth, for the period
indicated, certain information concerning the exchange rate for Swiss francs
into U.S. dollars based upon the noon buying rate in New York City for cable
transfers in foreign currencies as determined from publicly available sources:

<TABLE>
                                             (SFR. PER U.S. DOLLAR)

<CAPTION>
                 Period                       At December 31      Average Rate(1)        High             Low
                 ------                       --------------      ---------------     --- - ----      --- - ----
<S>                                             <C>                 <C>               <C>             <C>
     1993...................................... Sfr. 1.4850         Sfr. 1.4778       Sfr. 1.5470     Sfr. 1.3849

<FN>
- ------------------

  (1)The average of the exchange rates on the last day of each month during
    the year.

</TABLE>
<TABLE>
                                                  THE ROCHE GROUP


                                       SELECTED CONSOLIDATED FINANCIAL DATA

                                                   (in millions)


<CAPTION>
                                                                                                   Fiscal Year Ended
                                                                                                   December 31, 1993
                                                                                                   -----------------
<S>                                                                                                <C>
CONSOLIDATED STATEMENT OF INCOME
Sales..............................................................................................Sfr.  14,315
Cost of goods sold and delivered...................................................................      (5,483)
Gross profit.......................................................................................       8,832
Marketing and selling..............................................................................      (3,222)
Research and development...........................................................................      (2,163)
Administrative.....................................................................................        (821)
Other operating income (expense), net..............................................................        (278)
Financial income, net..............................................................................         786
Income before taxes................................................................................       3,134
Taxes..............................................................................................        (622)
Income before accounting change and minority interests.............................................       2,512
Accounting change for post-retirement benefits other than pensions.................................          --
Income applicable to minority interests............................................................         (34)
Net income.........................................................................................Sfr.   2,478
</TABLE>
<TABLE>
                                                  THE ROCHE GROUP


                                       SELECTED CONSOLIDATED FINANCIAL DATA

                                                   (in millions)


<CAPTION>
                                                                                                   Fiscal Year Ended
                                                                                                   December 31, 1993
                                                                                                   -----------------

<S>                                                                                                <C>
CONSOLIDATED BALANCE SHEET
ASSETS:
Long-term assets:
  Property, plant and equipment....................................................................Sfr.   6,789
  Intangible assets................................................................................       1,496
  Other long-term assets...........................................................................       1,345
                                                                                                         ------
    Total long-term assets.........................................................................       9,630
                                                                                                         ------
Current assets:
  Inventories......................................................................................       3,127
  Accounts, receivable-trade ......................................................................       2,664
  Other receivables and prepaid expenses...........................................................         917
  Marketable securities............................................................................      12,693
  Cash.............................................................................................       1,895
                                                                                                         ------
    Total current assets...........................................................................      21,296
                                                                                                         ------
     Total assets..................................................................................Sfr.  30,926
                                                                                                         ======

EQUITY AND LIABILITIES:
Equity:
  Share capital....................................................................................         160
  Retained earnings and reserves...................................................................      17,754
                                                                                                         ------
  Shareholders'equity per accompanying statement...................................................      17,914
  Minority interests...............................................................................         625
                                                                                                         ------
    Total stockholders' equity and minority interests..............................................      18,539
                                                                                                         ------
Long-term debt.....................................................................................       4,498
                                                                                                         ------
Noncurrent liabilities:
  Deferred income taxes............................................................................         888
  Pensions and similar obligations.................................................................         725
  Other............................................................................................       1,810
                                                                                                         ------
    Total noncurrent liabilities...................................................................       3,423
                                                                                                         ------
Current liabilities:
  Accounts payable - trade.........................................................................         662
  Other payables and accrued liabilities...........................................................       2,984
  Current portion of long-term debt................................................................         163
  Short-term debt..................................................................................         657
                                                                                                         ------
    Total current liabilities......................................................................       4,466
                                                                                                         ------
     Total equity and liabilites...................................................................Sfr.  30,926
                                                                                                         ======
</TABLE>
Item 10.  Additional Information.


     (b)  Pursuant to Section 721 of the Defense Production Act of 1950, as
amended ("Exon-Florio"), on May 16, 1994, Bidder and the Company jointly filed
with the Committee on Foreign Investment in the United States ("CFIUS") notice
of the transactions contemplated in the Merger Agreement.

                                   SIGNATURE


     After due inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and
correct.



                                        ROCHE CAPITAL CORPORATION


By:
                                        DR. HENRI B. MEIER
                                        Dr. Henri B. Meier
                                        Vice-President


Dated: May 16, 1994


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