SYNTEX CORP
SC 14D1/A, 1994-09-01
PHARMACEUTICAL PREPARATIONS
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                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D. C. 20549

                               AMENDMENT NO. 11
                                      TO
                                SCHEDULE 14D-1
                  Tender Offer Statement Pursuant to Section
                14(d)(1) of the Securities Exchange Act of 1934
                              Syntex Corporation
                           (Name of Subject Company)
                           Roche Capital Corporation
                                   (Bidder)
                    Common Stock, Par Value $1.00 Per Share
                        (Title of Class of Securities)
                                   87161610
                     (CUSIP Number of Class of Securities)
                               Dr. Felix Amrein
                             c/o Roche Holding Ltd
                             Grenzacherstrasse 124
                                 CH-4002 Basel
                                  Switzerland
                         Telephone: (41) (61) 688-1111
  (Name, Address and Telephone Number of Person Authorized to Receive Notices
                                      and

                      Communications on Behalf of Bidder)

                                  Copies to:
                               Peter R. Douglas
                             Davis Polk & Wardwell
                             450 Lexington Avenue
                           New York, New York  10017
                          Telephone:  (212) 450-4000
                                  May 6, 1994

     Date Tender Offer First Published, Sent or Given to Security Holders



 CUSIP No.  871 616 10


1   NAME OF REPORTING PERSON
    S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
        Roche Capital Corporation

2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                          (a)  [ ]
                                                          (b)  [ ]

3   SEC USE ONLY

4   SOURCE OF FUNDS*
        AF, BK

5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
    ITEMS 2 (e) OR 2 (f) [ ]

6   CITIZENSHIP OR PLACE OF ORGANIZATION
        Panama

7   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
        0

8   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (7) EXCLUDES CERTAIN SHARES*  [ ]

9   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (7)
        N/A

10  TYPE OF REPORTING PERSON*
        CO




     This Amendment No. 11 amends and supplements the Tender Offer Statement
on Schedule 14D-1 (the "Statement")  dated May 6, 1994 filed by Roche Capital
Corporation, a Panama corporation (the "Bidder") and a wholly owned subsidiary
of Sapac Corporation Limited, a non-resident Canadian corporation ("Holding"),
which, in turn, is a wholly owned subsidiary of Roche Holding Ltd, a
Switzerland corporation ("Parent"), as amended by Amendments Nos. 1, 2, 3, 4,
5, 6, 7, 8, 9 and 10 relating to the Bidder's offer to purchase all
outstanding shares of Common Stock, $1.00 par value (the "Shares") of Syntex
Corporation (the "Company"), at $24.00 per Share, net to the seller in cash,
upon the terms and subject to the conditions set forth in the Offer to
Purchase and the related Letter of Transmittal, copies of which are attached
as Exhibits (a)(1)  and (a)(2) to the Statement (which are herein referred to
as the "Offer"). Capitalized terms not separately defined herein shall have
the meanings specified in the Statement.

Item 10.  Additional Information.

     (f)  On September 1, 1994, the Bidder and the Company issued the joint
press release attached hereto as Exhibit (a)(13).  The information set forth
in the press release is incorporated herein by reference.

Item 11.  Material to be Filed as Exhibits.

     (a)(13)  Joint Press Release, dated September 1, 1994.

                                   SIGNATURE


     After due inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and
correct.


                                        ROCHE CAPITAL CORPORATION


                                    By: /s/ DR. HENRI B. MEIER
                                        ----------------------
                                        Dr. Henri B. Meier
                                        Vice-President


Dated: September 1, 1994



                             FOR IMMEDIATE RELEASE


     ROCHE HOLDING LTD TENDER OFFER FOR SYNTEX CORPORATION COMPLETED

     BASEL, SWITZERLAND AND PALO ALTO, CALIFORNIA -- SEPTEMBER 1, 1994 --
Roche Holding Ltd and Syntex Corporation (NYSE: SYN) announced today that the
offer by Roche Capital Corporation to purchase all outstanding shares of
common stock of Syntex for $24.00 per share in cash expired, as scheduled, at
midnight, New York City time on Wednesday, August 31, 1994.  Roche Capital
accepted for purchase all Syntex shares validly tendered and not withdrawn
prior to expiration of the offer.

     As of the expiration of offer, approximately 211.2 million shares
 (95.4 per cent of the 221.4 million shares outstanding) of Syntex common
 stock, including shares tendered pursuant to guaranties of delivery, had
 been validly tendered and not withdrawn.  Payment for shares validly
 tendered is expected to be made by First Chicago Trust Company of New
 York, acting as depositary for the tender offer, within approximately five
 business days; payment for shares delivered pursuant to guaranties of
 delivery is expected to be made within approximately five business days
 after the expiration of the deadline for delivery of share certificates
 pursuant to the guarantied delivery procedure.

                                      ###


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