CONNETICS CORP
DEF 14A, 1998-04-03
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1

 
                                  SCHEDULE 14A
                                 (RULE 14A-101)
 
                    INFORMATION REQUIRED IN PROXY STATEMENT
 
                            SCHEDULE 14A INFORMATION
          PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES
                    EXCHANGE ACT OF 1934 (AMENDMENT NO.   )
 
Filed by the Registrant [X]
 
Filed by a Party other than the Registrant [ ]
 
Check the appropriate box:
 
<TABLE>
<S>                                             <C>
[ ]  Preliminary Proxy Statement                [ ]  Confidential, for Use of the Commission
                                                     Only (as permitted by Rule 14a-6(e)(2))
[X]  Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12
</TABLE>
 
                             Connetics Corporation
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)
 
- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)
 
Payment of Filing Fee (Check the appropriate box):
 
[X]  No fee required.
 
[ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.
 
     (1)  Title of each class of securities to which transaction applies:
 
     (2)  Aggregate number of securities to which transaction applies:
 
     (3)  Per unit price or other underlying value of transaction computed
          pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
          filing fee is calculated and state how it was determined):
 
     (4)  Proposed maximum aggregate value of transaction:
 
     (5)  Total fee paid:
 
[ ]  Fee paid previously with preliminary materials:
 
[ ]  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the filing for which the offsetting fee was paid
     previously. Identify the previous filing by registration statement number,
     or the Form or Schedule and the date of its filing.
 
     (1)  Amount Previously Paid:
 
     (2)  Form, Schedule or Registration Statement No.:
 
     (3)  Filing Party:
 
     (4)  Date Filed:

<PAGE>   2
 
                             CONNETICS CORPORATION
                            3400 WEST BAYSHORE ROAD
                          PALO ALTO, CALIFORNIA 94303
 
Dear Fellow Stockholders:
 
     You are cordially invited to attend the 1998 Annual Meeting of Stockholders
(the "Annual Meeting") of Connetics Corporation ("Connetics" or the "Company"),
which will be held on Friday, May 22, 1998, at 9:00 a.m., local time, at the
Company's principal executive offices in Palo Alto, California.
 
     At the Annual Meeting, you will be asked to consider and vote upon the
following proposals: (i) the election of nine directors of the Company, (ii) an
amendment to the Company's 1994 Stock Plan to increase the number of shares of
Common Stock issuable thereunder by 600,000 shares, (iii) an amendment to the
Company's 1995 Directors' Stock Plan to increase the number of shares of Common
Stock issuable thereunder by 100,000 shares, (iv) an amendment to the Company's
1995 Employee Stock Purchase Plan to increase the number of shares of Common
Stock issuable thereunder by 400,000 shares, and (v) the ratification of Ernst &
Young LLP as independent auditors of the Company for the year ended December 31,
1998.
 
     The enclosed Proxy Statement more fully describes the details of the
business to be conducted at the Annual Meeting.
 
     After careful consideration, the Company's Board of Directors has
unanimously approved the proposals and recommends that you vote IN FAVOR OF each
such proposal.
 
     After reading the Proxy Statement, please mark, date, sign and return (if
possible, by no later than May 8, 1998) the enclosed proxy card in the
accompanying reply envelope. If you decide to attend the Annual Meeting and wish
to vote in person, please notify the Secretary of the Company and your proxy
will not be voted. YOUR SHARES CANNOT BE VOTED UNLESS YOU SIGN, DATE AND RETURN
THE ENCLOSED PROXY, OR ATTEND THE ANNUAL MEETING IN PERSON.
 
     A copy of the Company's 1997 Annual Report is also enclosed.
 
     We look forward to seeing you at the Annual Meeting.
 
Sincerely yours,
 
Thomas G. Wiggans
President and Chief Executive Officer
 
Palo Alto, California
March 31, 1998
 
                                   IMPORTANT
PLEASE MARK, DATE AND SIGN THE ENCLOSED PROXY AND RETURN IT AT YOUR EARLIEST
CONVENIENCE IN THE ENCLOSED POSTAGE-PREPAID RETURN ENVELOPE SO THAT IF YOU ARE
UNABLE TO ATTEND THE ANNUAL MEETING, YOUR SHARES MAY BE VOTED.
<PAGE>   3
 
                             CONNETICS CORPORATION
                            ------------------------
 
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                            TO BE HELD MAY 22, 1998
                            ------------------------
 
     The Annual Meeting of Stockholders (the "Annual Meeting") of Connetics
Corporation ("Connetics" or the "Company") will be held at the Company's
principal executive offices at 3400 West Bayshore Road, Palo Alto, California
94303, on Friday, May 22, 1998, at 9:00 a.m., for the following purposes:
 
     1. To elect nine (9) directors to hold office until the next Annual Meeting
        of Stockholders or until their respective successors are duly elected
        and qualified.
 
     2. To approve an amendment to the Company's 1994 Stock Plan to increase the
        number of shares of Common Stock reserved for issuance thereunder by
        600,000 shares to an aggregate of 2,600,000 shares.
 
     3. To approve an amendment to the Company's 1995 Directors' Stock Plan to
        increase the number of shares of Common Stock reserved for issuance
        thereunder by 100,000 shares to an aggregate of 250,000 shares.
 
     4. To approve an amendment to the Company's 1995 Employee Stock Purchase
        Plan to increase the number of shares of Common Stock reserved for
        issuance thereunder by 400,000 shares to an aggregate of 500,000 shares.
 
     5. To ratify the appointment of Ernst & Young LLP as independent auditors
        of the Company for the year ending December 31, 1998.
 
     6. To transact such other business as may properly come before the Annual
        Meeting or any adjournment thereof.
 
     The foregoing items of business are more fully described in the Proxy
Statement accompanying this Notice.
 
     The record date for determining those stockholders entitled to notice of,
and to vote at, the Annual Meeting and any adjournment thereof is March 30,
1998. A complete list of the stockholders entitled to vote at the Annual Meeting
will be available for inspection at the offices of the Company for at least ten
days prior to the Annual Meeting.
 
     All stockholders are cordially invited to attend the Annual Meeting.
However, to assure your representation at the meeting, please carefully read the
accompanying Proxy Statement which describes the matters to be voted upon at the
Annual Meeting and sign, date and return the enclosed proxy card in the reply
envelope provided. Should you receive more than one proxy because your shares
are registered in different names and addresses, each proxy should be returned
to assure that all your shares will be voted. If you attend the Annual Meeting
and vote by ballot, your proxy vote will be revoked automatically and only your
vote at the Annual Meeting will be counted. The prompt return of your proxy card
will assist us in preparing for the Annual Meeting.
 
                                          By Order of the Board of Directors,
 
                                          Joshua L. Green,
                                          Secretary
 
                                          Palo Alto, California
                                          March 31, 1998
<PAGE>   4
 
                             CONNETICS CORPORATION
                            ------------------------
 
                                PROXY STATEMENT
                            ------------------------
 
     This Proxy Statement is furnished in connection with the solicitation of
proxies on behalf of the Board of Directors of Connetics Corporation, a Delaware
corporation, with principal executive offices at 3400 West Bayshore Road, Palo
Alto, California 94303 ("Connetics" or the "Company"), to be voted upon at the
Annual Meeting of Stockholders on Friday, May 22, 1998 (the "Annual Meeting")
and at any adjournment or adjournments thereof.
 
     These proxy materials were first mailed to stockholders on or about April
6, 1998.
 
                               PURPOSE OF MEETING
 
     The specific proposals to be considered and acted upon at the Annual
Meeting are summarized in the accompanying Notice of Annual Meeting of
Stockholders. Each proposal is described in more detail in this Proxy Statement.
 
                            REVOCABILITY OF PROXIES
 
     Any stockholder giving a proxy pursuant to this solicitation may revoke it
at any time prior to exercise of such proxy by providing written notice of such
revocation to the Secretary of the Company at its offices at 3400 West Bayshore
Road, Palo Alto, California 94303, or by providing a duly executed proxy bearing
a later date, or by attending the meeting and voting in person.
 
                            VOTING AND SOLICITATION
 
     Stockholders of record at the close of business on March 30, 1998 are
entitled to notice of and to vote at the Annual Meeting. As of the close of
business on such date, the Company had 13,518,150 shares of Common Stock
outstanding and entitled to vote and approximately 182 stockholders of record,
including several holders who are nominees for an undetermined number of
beneficial owners. Each holder of Common Stock is entitled to one vote for each
share held as of the record date.
 
     All votes will be tabulated by the inspector of election appointed for the
meeting, who will separately tabulate affirmative and negative votes,
abstentions and broker non-votes. Abstentions will be counted towards the
tabulation of votes cast on proposals presented to the stockholders and will
have the same effect as negative votes, whereas broker non-votes will not be
counted for purposes of determining whether a proposal has been approved or not.
 
     The cost of soliciting these proxies, consisting of the printing, handling
and mailing of the proxy card and related material, and the actual expense
incurred by brokerage houses, custodians, nominees and fiduciaries in forwarding
proxy material to the beneficial owners of stock, will be paid by the Company.
In order to assure a majority vote will be present in person or by proxy at the
Annual Meeting, it may be necessary for certain officers, directors, regular
employees and other representatives of the Company to solicit proxies by
telephone, facsimile, telegraph or in person. These persons will receive no
extra compensation for their services. The Company also reserves the right to
have an outside solicitor conduct the solicitation of proxies and to pay such
solicitor for its services.
 
     The Annual Report of the Company for the year ended December 31, 1997 has
been mailed to all stockholders entitled to notice of and to vote at the Annual
Meeting. The Annual Report is not incorporated into this Proxy Statement and is
not considered proxy soliciting material.
<PAGE>   5
 
          ------------------------------------------------------------
 
                                 PROPOSAL NO. 1
 
                             ELECTION OF DIRECTORS
 
          ------------------------------------------------------------
 
     At the Annual Meeting, nine (9) directors will be elected by the
stockholders to serve until the next Annual Meeting or until their successors
are elected and qualified, or until their death, resignation or removal. The
Board of Directors will vote all proxies received by them IN FAVOR OF the nine
(9) nominees listed below unless otherwise instructed in writing on such proxy.
In the event any nominee is unable to or declines to serve as a director at the
time of the Annual Meeting, the proxies will be voted for an additional nominee
who will be designated by the current Board of Directors to fill the vacancy. As
of the date of this Proxy Statement, the Board of Directors is not aware of any
nominee who is unable or will decline to serve as director.
 
INFORMATION WITH RESPECT TO NOMINEES
 
     Set forth below is information regarding the nominees, including
information furnished by them as to their principal occupation at present and
for the last five years, certain other directorships held by them, the year in
which each became a director of the Company and their ages as of December 31,
1997:
 
<TABLE>
<CAPTION>
               NOMINEE                 AGE            POSITION(S) WITH THE COMPANY
               -------                 ---            ----------------------------
<S>                                    <C>   <C>
G. Kirk Raab(1)......................  62    Chairman of the Board
Thomas G. Wiggans....................  46    President, Chief Executive Officer and Director
Alexander E. Barkas, Ph.D.(1)........  50    Director
Eugene A. Bauer, M.D. ...............  55    Director
Brian H. Dovey.......................  56    Director
John C. Kane(2)......................  58    Director
Thomas D. Kiley(1)...................  54    Director
Kenneth B. Plumlee(1)................  37    Director
Joseph J. Ruvane, Jr.(2).............  72    Director
</TABLE>
 
- ---------------
 
(1) Member of the Audit Committee.
 
(2) Member of the Compensation Committee.
 
     G. Kirk Raab has served as the Chairman of the Board of Directors of the
Company since October 1995. From 1985 to January 1990, Mr. Raab served as
President and Chief Operating Officer of Genentech, Inc., a biotechnology
company, and from January 1990 to July 1995, he served as Genentech's President
and Chief Executive Officer. Prior to joining Genentech, Inc. in 1985, Mr. Raab
was President, Chief Operating Officer, and a Director of Abbott Laboratories,
and before that, held executive positions with Beecham Group, A.H. Robins and
Pfizer, Inc. He is also Chairman of Shaman Pharmaceuticals, Inc., and a director
of Applied Imaging Inc., and LXR Biotechnology Inc., as well as five private
biotechnology companies.
 
     Thomas G. Wiggans has served as President, Chief Executive Officer and as a
director of the Company since July 1994. From February 1992 to April 1994, Mr.
Wiggans served as President and Chief Operating Officer of CytoTherapeutics, a
biotechnology company. From 1980 to February 1992, Mr. Wiggans served at various
positions at Ares-Serono Group, a pharmaceutical company, including President of
its U.S. pharmaceutical operations and Managing Director of its U.K.
pharmaceutical operations. From 1976 to 1980 he held various sales and marketing
positions with Eli Lilly & Co., a pharmaceutical company. He is currently a
director of the Biotechnology Industry Organization, and a member of the
governing body of its emerging company section. He was also President of the
Board of Directors of the Association of Biotechnology Companies.
 
                                        2
<PAGE>   6
 
     Alexander E. Barkas, Ph.D., has served as a director of the Company since
November 1993. Dr. Barkas served as Acting Chairman of the Board of Directors of
the Company from January 1994 to August 1994 and as Chairman of the Board of
Directors of the Company from August 1994 to October 1995. Dr. Barkas has been a
Managing Partner of Prospect Venture Partners, a venture capital investment
firm, since June 1997. He was previously a partner with Kleiner Perkins Caufield
& Byers, a venture capital investment firm from September 1991 to June 1997. Dr.
Barkas also serves as Chairman of the Board of Directors of Geron Corporation
and as a director of several privately-held medical technology companies.
 
     Eugene A. Bauer, M.D., has served as a director of the Company since
January 1996 and also served as a director from the Company's inception in
February 1993 to September 1995. Dr. Bauer has been Dean of the Stanford
University School of Medicine since 1995, Professor, Department of Dermatology,
Stanford University School of Medicine since 1988, and Chief of the Dermatology
Service at Stanford University Hospital from 1988 to 1995. Previously, he was a
professor at Washington University School of Medicine from 1982 to 1988. He has
served as chairman of two National Institutes of Health study sections of the
National Institute of Arthritis and Musculoskeletal and Skin Diseases and has
served on a board of scientific counselors for the National Cancer Institute.
Dr. Bauer is currently a director of Reconstructive Technologies, Inc.
 
     Brian H. Dovey has served as a director of the Company since February 1995.
Mr. Dovey has been a general partner of Domain Associates, a venture capital
investment firm since 1988. From 1986 to 1988, Mr. Dovey was President of Rorer
Group, Inc., a pharmaceutical company. Mr. Dovey also serves on the board of
directors of Creative BioMolecules, Inc., Geron Corporation, NABI, Inc.,
Trimeris, Inc. and Vivus, Inc., all publicly-held companies and as a director of
several privately-held companies.
 
     John C. Kane has served as a director of the Company since March 1997. Mr.
Kane joined Cardinal Health, Inc., a healthcare services provider, as President
and Chief Operating Officer in March 1993. Prior to joining Cardinal, Mr. Kane
served in various operational and management positions at Abbott Laboratories
for 19 years, most recently as President of Ross Laboratories Division. Mr. Kane
is a director of Cardinal Health, Inc. and serves on several medical advisory
councils and educational foundations.
 
     Thomas D. Kiley has served as a director of the Company since February
1993. He has been self-employed since 1988 as an attorney, consultant and
investor. From 1980 to 1988, he was an officer of Genentech, serving variously
as Vice President and General Counsel, Vice President for Legal Affairs and Vice
President for Corporate Development. From 1969 to 1980, he was with the Los
Angeles law firm of Lyon & Lyon and was a partner in such firm from 1975 to
1980. Mr. Kiley is also a director of Cardiogensis, Inc., Geron Corporation,
Pharmacyclics, Inc. and certain private biotechnology and other companies.
 
     Kenneth B. Plumlee has served as a director of the Company since January
1997. Mr. Plumlee is currently a principal of Waterpath Investments, an
investment company focusing on health care information technology and consumer
health information services, which he founded in 1996. Mr. Plumlee also founded
Access Health Inc., a healthcare information company, in October 1988 and served
as its President from the Company's founding until June 1996. Mr. Plumlee also
served as Chief Executive Officer of Access Health Inc. through September 1996
and as Chairman until April 1997 and continues to serve as a director. From 1986
to 1988, Mr. Plumlee was responsible for the development of Ask-A-Nurse at
Adventist Health System, a healthcare company, which was later acquired by
Access Health Inc.
 
     Joseph J. Ruvane, Jr. has served as a director of the Company since
November 1995. From 1981 to 1988, Mr. Ruvane was President, Chief Executive
Officer, and Chairman of Glaxo, Inc., a pharmaceutical company. Mr. Ruvane has
also served as the executive director of Glaxo Holdings PLC. Mr. Ruvane
currently serves on the board of Intercardia, a public company and serves on the
board of Pozen Inc., a private company. He serves on the Thelonious Monk
Institute of Jazz National Advisory Board and on the University of Virginia Art
and Sciences Alumni Council.
 
     The Company currently has authorized nine directors. Each director is
elected for a period of one year at the Company's annual meeting of stockholders
and serves until the next annual meeting or until his successor is duly elected
and qualified. The executive officers serve at the discretion of the Board of
Directors. There are no family relationships among any of the directors or
executive officers of the Company.
 
                                        3
<PAGE>   7
 
BOARD OF DIRECTORS COMMITTEES, COMPENSATION OF DIRECTORS AND OTHER INFORMATION
 
     All directors hold office until the next annual meeting of stockholders of
the Company or until their successors have been elected and qualified. The
officers of the Company are appointed annually and serve at the discretion of
the Board of Directors.
 
     The Board of Directors held a total of five (5) regular meetings during the
year ended December 31, 1997 and three (3) special meetings. Each incumbent
director attended at least 75% of the aggregate number of meetings of the Board
of Directors and of the Committees on which such directors served and that were
held during the period that such individual was a member of the Board of
Directors, except that Dr. Bauer was able to attend only three (3) of the
regular meetings during the year and two (2) of the special meetings.
 
     The Company's Compensation Committee was formed in June 1994 to review and
approve the compensation and benefits for the Company's executive officers,
administer the Company's stock purchase and stock option plans and make
recommendations to the Board of Directors regarding such matters. The committee
is currently composed of Mr. Kane and Mr. Ruvane. In addition, although no
longer a member, Mr. Dovey served on the Compensation Committee during 1997. The
Compensation Committee held four (4) meetings during the year ended December 31,
1997.
 
     The Board of Directors also has an Audit Committee (consisting of Mr.
Barkas, Mr. Kiley, Mr. Plumlee and Mr. Raab), which reviews the results and
scope of the audit and other services provided by the Company's independent
accountants. The Audit Committee held four (4) meetings in 1997.
 
     Non-employee directors currently receive $1,000 per quarter and $1,000 per
meeting for services provided in that capacity and are reimbursed for
out-of-pocket expenses incurred in connection with attendance at meetings of the
Board of Directors.
 
     In October 1995, the Company entered into a Consulting Agreement with G.
Kirk Raab under which Mr. Raab serves as a director, consultant and the Chairman
of the Company's Board of Directors. Pursuant to such agreement, the Company
pays Mr. Raab a base annual director's fee of $150,000. In February 1998, the
Compensation Committee approved an increase in the annual fee to $180,000. Under
his Consulting Agreement, Mr. Raab was also granted an option to purchase 67,450
shares of the Company's Common Stock at an exercise price of $0.45 per share.
Such shares vest at the rate of 8,431 shares on April 1, 1996 and 1,405 shares
each month thereafter. In January 1996, Mr. Raab was granted an additional
option to purchase 50,000 shares of the Company's Common Stock at an exercise of
$11.00 per share. Such shares vest at the rate of 6,250 shares on July 29, 1996
and 1,041 shares each month thereafter. In January 1997, Mr. Raab was granted an
additional option to purchase 25,000 shares of the Company's Common Stock at an
exercise price of $7.125 per share. Such shares vest at the rate of 6,250 on
January 28, 1998, and 1,562 shares each quarter thereafter. Additionally, Mr.
Raab was granted an additional option to purchase 5,000 shares of the Company's
Common Stock in July 1997 at an exercise price of $7.75. Such shares vest at the
rate of 1,250 on January 28, 1998 and 312 shares each quarter thereafter,
provided Mr. Raab continues his service as a director or consultant to the
Company. Mr. Raab is reimbursed for out-of-pocket expenses incurred in
connection with attendance at meetings of the Board of Directors.
 
     Non-employee directors of the Company are automatically granted options to
purchase shares of the Company's Common Stock pursuant to the terms of the
Company's 1995 Directors' Stock Option Plan. The Directors' Plan provides that
each person who first becomes a non-employee director of the Company after the
date of the Company's initial public offering, shall be granted a non-statutory
stock option to purchase 30,000 shares of Common Stock (the "First Option") on
the date on which the optionee first becomes a non-employee director of the
Company. The First Option was not granted to individuals serving as non-employee
directors as of the date of the initial public offering. Thereafter, on the date
of each annual meeting of the Company's stockholders at which a non-employee
director is elected, such non-employee director (including any director who was
not granted a First Option prior to the date of such annual meeting) shall be
granted an option to purchase 7,500 shares of Common Stock (a "Subsequent
Option") if, on such date, he or she has served on the Company's Board of
Directors for at least six months. The Directors' Plan provides that the First
Option shall become exercisable in installments as to 25% of the total number of
shares subject to the First
 
                                        4
<PAGE>   8
 
Option on each of the first, second, third and fourth anniversaries of the date
of grant of the First Option; each Subsequent Option shall become exercisable in
full on the first anniversary of the date of grant of that Subsequent Option.
The exercise price of all stock options granted under the Directors' Plan shall
be equal to the fair market value of a share of the Company's Common Stock on
the date of grant of the option.
 
REQUIRED VOTE
 
     The nine nominees receiving the highest number of affirmative votes of the
Company's Common Stock present at the Annual Meeting in person or by proxy and
entitled to vote shall be elected as directors.
          ------------------------------------------------------------
 
                                 PROPOSAL NO. 2
 
                   APPROVAL OF AMENDMENTS TO 1994 STOCK PLAN
 
          ------------------------------------------------------------
 
     At the Annual Meeting, the Company's stockholders are being asked to
approve an amendment to the Company's 1994 Stock Plan (the "1994 Plan") to
increase the number of shares of Common Stock reserved for issuance thereunder
by 600,000 shares to an aggregate of 2,600,000 shares.
 
GENERAL
 
     The 1994 Plan was adopted by the Board of Directors in August 1994. The
Board of Directors initially reserved 337,253 shares of Common Stock for
issuance pursuant to stock options and stock purchase rights under the 1994
Plan. The 1994 Plan was approved by the Company's stockholders in August 1994.
An additional 1,011,759 shares were approved for issuance under the 1994 Plan in
September 1995, with an additional 150,988 shares in January 1996 and an
additional 500,000 in January 1997. In February 1998, the Board of Directors
amended the 1994 Plan to increase the number of shares reserved for issuance
thereunder by 600,000 shares to an aggregate of 2,600,000, for which stockholder
approval is requested.
 
     The Board of Directors believes that, in order to attract qualified
employees to the Company and to provide incentive to its current employees and
consultants, it is necessary to increase the number of shares available for
granting options or rights to purchase Common Stock to such employees pursuant
to the 1994 Plan. Accordingly, stockholders are being asked to approve the
amendment to the 1994 Plan at the Annual Meeting.
 
     Options granted under the 1994 Plan may be either "incentive stock options"
within the meaning of Section 422 of the Internal Revenue Code of 1986, as
amended (the "Code"), or nonstatutory stock options at the discretion of the
Board of Directors and as reflected in the terms of the written option
agreement. The Board of Directors, at its discretion, may also grant rights to
purchase Common Stock directly, rather than pursuant to stock options, subject
to certain restrictions discussed below.
 
     The 1994 Plan is not a qualified deferred compensation plan under Section
401(a) of the Code, and is not subject to the provisions of the Employee
Retirement Income Security Act of 1974, as amended.
 
     As of February 27, 1998 options for 1,584,413 shares were outstanding under
the 1994 Plan, 307,852 shares had been issued pursuant to the exercise of
options granted under such plan and 107,735 shares remained available for future
grants. No stock purchase rights have been granted under the 1994 Plan. Shares
not exercised or purchased under an option prior to its expiration will be
available for future option grants under the 1994 Plan. As of February 27, 1998,
the aggregate fair market value of shares subject to outstanding options under
the 1994 Plan was $6,535,703.63, based upon the closing price of the Common
Stock as reported on The Nasdaq Stock Market on such date. The actual benefits,
if any, to the holders of stock options issued under the 1994 Plan are not
determinable as grants under the 1994 Plan are discretionary and, prior to
exercise, the value, if any, of such stock options to their holders is
represented by the difference between the market price of a share of the
Company's Common Stock on the date of exercise and the exercise price of a
holder's stock option.
 
                                        5
<PAGE>   9
 
     As of February 27, 1998, since the adoption of the 1994 Plan, 775,769
options shares have been granted to executive officers, 678,010 option shares
have been granted to other employees and 216,174 option shares have been granted
to non-employee directors. Options to purchase 298,000 shares of Common Stock
were granted to the Company's executive officers during the fiscal year ended
December 31, 1997 under the Company's 1994 Stock Plan.
 
PURPOSE
 
     The purposes of the 1994 Plan are to attract and retain the best available
personnel for positions of substantial responsibility, to provide additional
incentive to employees and consultants of the Company and to promote the success
of the Company's business.
 
ADMINISTRATION
 
     The 1994 Plan may be administered by the Board of Directors or by a
committee (or committees) of the Board of Directors. The 1994 Plan is currently
being administered by the Compensation Committee of the Board of Directors.
Members of the Compensation Committee receive no additional compensation for
their services in connection with the administration of the 1994 Plan. All
questions of interpretation of the 1994 Plan are determined by the Compensation
Committee and its decisions are final and binding upon all participants.
 
ELIGIBILITY
 
     The 1994 Plan provides that either incentive stock options or nonstatutory
stock options may be granted to employees (including officers and directors who
are also employees) of the Company or any of its subsidiaries. In addition, the
1994 Plan provides that nonstatutory stock options and stock purchase rights may
be granted to consultants or non-employee directors of the Company or any of its
subsidiaries.
 
     The Board of Directors or its committee selects participants to be issued
stock options or stock purchase rights under the 1994 Plan and determines the
number of shares to be subject to each option or purchase right. In making such
determination, certain factors are taken into account, including the duties and
responsibilities of the participant, the value of the participant's services,
the participant's present and potential contribution to the success of the
Company, and other relevant factors.
 
     The 1994 Plan provides that the maximum number of shares of Common Stock
which may be granted under options or purchase rights to any one employee or
consultant during any fiscal year shall be 150,000, subject to adjustment as
provided in the 1994 Plan. There is also a limit on the aggregate market value
of shares subject to all incentive stock options that may be granted to an
optionee during any calendar year.
 
TERMS OF OPTIONS
 
     Each option is evidenced by a stock option agreement between the Company
and the optionee. Each option is subject to the following additional terms and
conditions:
 
          (a) Exercise of the Option.  The Board of Directors or its committee
     determines when options may be exercised. An option is exercised by giving
     written notice of exercise to the Company specifying the number of full
     shares of Common Stock to be purchased and by tendering payment of the
     purchase price. The purchase price of the shares purchased upon exercise of
     an option shall be paid in consideration of such form as is determined by
     the Board of Directors or its committee and specified in the option
     agreement, and such form of consideration may vary for each option.
 
          (b) Exercise Price.  The exercise price under the 1994 Plan is
     determined by the Board of Directors or its committee and may not be less
     than 100 percent of the fair market value of the Common Stock on the date
     the option is granted for both incentive and nonstatutory stock options.
     The fair market value per share is equal to the closing price on The Nasdaq
     Stock Market on the date of grant. In the case of an incentive stock option
     granted to an optionee who owns more than ten percent of the total combined
 
                                        6
<PAGE>   10
 
     voting power of all classes of stock of the Company or any of its
     subsidiaries (a "10% Stockholder"), the exercise price must not be less
     than 110 percent of the fair market value on the date of grant.
 
          (c) Termination of Service.  If the optionee's employment or
     consulting relationship terminates for any reason other than disability or
     death, options under the 1994 Plan may be exercised not later than the
     period of time after such termination determined by the Board or its
     committee (such period of time not to exceed three months in the case of
     incentive stock options, with such determination made at the time of grant)
     and may be exercised only to the extent the option was exercisable on the
     date of termination. In no event may an option be exercised by any person
     after the expiration of its term.
 
          (d) Disability.  If an optionee is unable to continue his or her
     employment or consulting relationship with the Company as a result of his
     total and permanent disability, options may be exercised within six months
     (or such other period of time not exceeding twelve months as is determined
     by the Board of Directors or its committee at the time of grant) of
     termination and may be exercised only to the extent the option was
     exercisable on the date of termination, but in no event may the option be
     exercised after the expiration of its term. In the event that the
     disability is total and permanent, options may be exercised within twelve
     months of termination (but in no event later than the expiration date).
 
          (e) Death.  Under the 1994 Plan, if an optionee should die during the
     term of the option, options may be exercised within twelve months after the
     date of death to the extent the options were exercisable on the date of
     death. In no event, however, may the option be exercised after expiration
     of its term.
 
          (f) Termination of Options.  The 1994 Plan provides that options
     granted under the 1994 Plan have the term provided in the option agreement.
     In general, these agreements currently provide for a term of ten years.
     Incentive stock options granted to an optionee who, immediately before the
     grant of such option, is a 10% Stockholder, may not in any case have a term
     of more than five years. No option may be exercised by any person after its
     expiration.
 
          (g) Option Not Transferable.  An option is nontransferable by the
     optionee other than by will or the laws of descent and distribution, and is
     exercisable only by the optionee during his or her lifetime or, in the
     event of the optionee's death, by a person who acquires the right to
     exercise the option by bequest or inheritance or by reason of the death.
 
          (h) Change of Control.  In the event of a merger or consolidation in
     which the Company is not the surviving entity, the Board of Directors may
     in its discretion provide that options not assumed or substituted by the
     successor corporation are to become exercisable in full (even as to
     unvested portions) prior to the consummation of the transaction.
 
RESTRICTED STOCK PURCHASE RIGHTS
 
     The 1994 Plan permits the granting of rights to purchase Common Stock of
the Company either alone, in addition to, or in tandem with other awards made by
the Company. Upon the granting of a stock purchase right under the 1994 Plan,
the offeree is advised in writing of the terms, conditions and restrictions
related to the offer, including the number of shares of Common Stock that such
person is entitled to purchase, the price to be paid and the time in which such
person must accept such offer. The purchase price for stock purchased pursuant
to such rights shall not be less than 85 percent of the fair market value of
such shares on the date of grant (or 100 percent of the fair market value if the
person is a Named Executive Officer or a 10% Stockholder). Stock purchase rights
granted to persons subject to Section 16 of the Securities Exchange Act of 1934,
as amended (the "Exchange Act"), will be subject to any restrictions necessary
to comply with Rule 16b-3.
 
     Unless the Administrator of the 1994 Plan determines otherwise, the
underlying stock purchase agreement for stock purchased pursuant to a stock
purchase right granted under the 1994 Plan will grant the Company a repurchase
option with respect to the unvested portion of the purchase right, which
repurchase option is exercisable upon the voluntary or involuntary termination
of the purchaser's employment with the Company for any reason (including death
or disability). The purchase price for shares repurchased shall be the original
purchase price paid by the purchaser.
                                        7
<PAGE>   11
 
ADJUSTMENTS UPON CHANGES IN CAPITALIZATION
 
     In the event any change, such as a stock split or dividend, is made in the
Company's capitalization that results in an increase or decrease in the number
of outstanding shares of Common Stock without receipt of consideration by the
Company, appropriate adjustment shall be made in the exercise price of each
outstanding stock option or stock purchase right, the number of shares subject
to each option or purchase right, the annual limitation on grants to employees,
as well as the number of shares available for issuance under the 1994 Plan. In
the event of the proposed dissolution or liquidation of the Company, each
outstanding option or purchase right will terminate unless otherwise provided by
the Board of Directors or its committee.
 
AMENDMENT AND TERMINATION
 
     The Board of Directors may amend the 1994 Plan at any time or from time to
time or may terminate it without approval of the stockholders; provided,
however, that stockholder approval is required for any amendment to the 1994
Plan that increases the number of shares that may be issued under the 1994 Plan,
changes the class of persons eligible to receive options, modifies the
limitation on grants to employees described in the 1994 Plan, results in other
changes which would require stockholder approval to qualify options granted
under the 1994 Plan as performance-based compensation under Section 162(m) of
the Code, or, would require stockholder approval in order to preserve
qualification of the 1994 Plan under SEC Rule 16b-3. However, no action by the
Board of Directors or stockholders may alter or impair any option previously
granted under the 1994 Plan. The 1994 Plan shall terminate in August 2004,
provided that any options then outstanding under the 1994 Plan shall remain
outstanding until they expire by their terms.
 
UNITED STATES FEDERAL INCOME TAX INFORMATION
 
     The following is a brief summary of the U.S. federal income tax
consequences of transactions under the 1994 Plan based on federal income tax
laws in effect on the date of this Proxy Statement. This summary is not intended
to be exhaustive and does not address all matters which may be relevant to a
particular optionee based on his or her specific circumstances. The summary
addresses only current U.S. federal income tax law and expressly does not
discuss the income tax laws of any state, municipality, non-U.S. taxing
jurisdiction or gift, estate or other tax laws other than federal income tax
law. The Company advises all optionees to consult their own tax advisors
concerning tax implications of option grants and exercises, the disposition of
stock acquired upon such exercises, and purchases and dispositions of stock
under stock purchase rights, under the 1994 Plan.
 
     Stock Options.  Options granted under the 1994 Plan may be either incentive
stock options, which are intended to qualify for the special tax treatment
provided by Section 422 of the Code, or nonstatutory stock options, which will
not so qualify. If an option granted under the 1994 Plan is an incentive stock
option, the optionee will recognize no income upon grant of the incentive stock
option and will incur no tax liability due to the exercise except to the extent
that such exercise causes the optionee to incur alternative minimum tax. (See
discussion below). The Company will not be allowed a deduction for federal
income tax purposes as a result of the exercise of an incentive stock option
regardless of the applicability of the alternative minimum tax. Upon the sale or
exchange of the shares more than two years after grant of the incentive stock
option and one year after exercise of the option by the optionee, any gain will
be treated as a long-term capital gain. If both of these holding periods are not
satisfied, the optionee will recognize ordinary income equal to the difference
between the exercise price and the lower of the fair market value of the Common
Stock at the date of the option exercise or the sale price of the Common Stock.
The Company will be entitled to a deduction in the same amount as the ordinary
income recognized by the optionee. Any gain or loss recognized on a disposition
of the shares prior to completion of both of the above holding periods in excess
of the amount treated as ordinary income will be characterized as long-term
capital gain if the sale occurs more than one year after exercise of the option
or as short-term capital gain if the sale is made earlier. For individual
taxpayers, the current U.S. federal income tax rate on long-term capital gains
is alternatively 28% (in the case of shares held more than one year but less
than 18 months after exercise), and 20% (in the case of shares held more than 18
months after exercise), whereas the maximum rate on other income is 39.6%.
Capital losses for individual taxpayers are allowed in full against capital
gains plus $3,000 of other income.
                                        8
<PAGE>   12
 
     All other options that do not qualify as incentive stock options are
referred to as nonstatutory stock options. An optionee will not recognize any
taxable income at the time he or she is granted a nonstatutory stock option.
However, upon its exercise, the optionee will recognize ordinary income for tax
purposes measured by the excess of the fair market value of the shares over the
exercise price. The income recognized by an optionee who is also an employee of
the Company will be subject to income and employment tax withholding by the
Company by payment in cash by the optionee or out of the optionee's current
earnings. Upon the sale of such shares by the optionee, any difference between
the sale price and the fair market value of the shares as of the date of
exercise of the option will be treated as capital gain or loss, and will qualify
for long-term capital gain or loss treatment if the shares have been held for
more than one year.
 
     Alternative Minimum Tax.  The exercise of an incentive stock option may
subject the optionee to the alternative minimum tax under Section 55 of the
Code. The alternative minimum tax is calculated by applying a tax rate of 26% to
alternative minimum taxable income of joint filers up to $175,000 ($87,500 for
married taxpayers filing separately) and 28% to alternative minimum taxable
income above that amount. Alternative minimum taxable income is equal to (i)
taxable income adjusted for certain items, plus (ii) items of tax preference
less (iii) an exemption amount of $45,000 for joint returns, $33,750 for
unmarried individual returns and $22,500 in the case of married taxpayers filing
separately (which exemption amounts are phased out for upper income taxpayers).
Alternative minimum tax will be due if the tax determined under the foregoing
formula exceeds the regular tax of the taxpayer for the year.
 
     In computing alternative minimum taxable income, shares purchased upon
exercise of an incentive stock option are treated as if they had been acquired
by the optionee pursuant to the exercise of a nonstatutory stock option. As a
result, the optionee recognizes alternative minimum taxable income equal to the
excess of the fair market value of the Common Stock on the date of exercise over
the option exercise price. Because the alternative minimum tax calculation may
be complex, optionees should consult their own tax advisors prior to exercising
incentive stock options.
 
     If an optionee pays alternative minimum tax as a result of the ISO
exercise, the amount of such tax may be carried forward as a credit against any
subsequent year's regular tax in excess of the alternative minimum tax for such
year.
 
     Stock Purchase Rights.  Stock purchases under the 1994 Plan will generally
be taxed in the same manner as the exercise of a nonstatutory stock option,
except that the recipient may elect to take into current income, and be taxed at
the time of purchase on, the difference (if any) between the purchase price and
the value of the shares.
 
REQUIRED VOTE
 
     The approval of the amendment to the 1994 Stock Plan to increase the number
of shares reserved for issuance thereunder by 600,000 shares requires the
affirmative vote of the holders of a majority of the shares of the Company's
Common Stock present at the Annual Meeting in person or by proxy and entitled to
vote.
 
RECOMMENDATION OF THE BOARD OF DIRECTORS
 
     The Board of Directors recommends a vote FOR the approval of the amendment
to the 1994 Plan and the reservation of shares for issuance thereunder. The
effect of an abstention is the same as that of a vote against the approval of
the adoption of the amendment to the 1994 Plan.
 
                                        9
<PAGE>   13
 
          ------------------------------------------------------------
 
                                 PROPOSAL NO. 3
 
                    APPROVAL OF AMENDMENT TO 1995 DIRECTORS'
                                   STOCK PLAN
 
          ------------------------------------------------------------
 
     At the Annual Meeting, the Company's stockholders are being asked to
approve an amendment to the Company's 1995 Directors' Stock Plan (the
"Directors' Plan") to increase the number of shares of Common Stock reserved for
issuance thereunder by 100,000 shares to an aggregate of 250,000 shares.
 
     The 1995 Directors' Plan was adopted by the Board of Directors in December
1995 and approved by the Company's stockholders in January 1996. A total of
150,000 shares of Common Stock have been reserved for issuance under the
Directors' Plan. In February 1998, the Company's Board of Directors approved an
amendment to the Directors' Plan to increase the number of shares of Common
Stock reserved for issuance thereunder by 100,000 shares to an aggregate of
250,000 shares, for which stockholder approval is requested.
 
GENERAL
 
     The Directors' Plan provides for the grant of nonstatutory stock options to
non-employee directors of the Company.
 
     As of February 27, 1998 options for 105,000 shares were outstanding under
the Directors' Plan, no shares had been issued pursuant to the exercise of
options granted under such plan and 45,000 shares remained available for future
grants. Shares not purchased under an option prior to its expiration will be
available for future option grants under the Directors' Plan. As of February 27,
1998, the aggregate fair market value of shares subject to outstanding options
under the Directors' Plan was $433,125.00, based upon the closing price of the
Common Stock as reported on The Nasdaq Stock Market on such date. The actual
benefits, if any, to the holders of stock options issued under the Directors'
Plan are not determinable prior to exercise as the value, if any, of such stock
options to their holders is represented by the difference between the market
price of a share of the Company's Common Stock on the date of exercise and the
exercise price of a holder's stock option, as set forth below.
 
     The Directors' Plan is not a qualified deferred compensation plan under
Section 401(a) of the Code, and is not subject to the provisions of the Employee
Retirement Income Security Act of 1974, as amended.
 
PURPOSE
 
     The purposes of this Directors' Stock Option Plan are to attract and retain
the best available personnel for service as Directors of the Company, to provide
additional incentive to the non-employee Directors of the Company to serve as
Directors, and to encourage their continued service on the Board.
 
ADMINISTRATION
 
     The Directors' Plan is designed to work automatically and not to require
administration; however, to the extent administration is necessary, it will be
provided by the Board of Directors.
 
ELIGIBILITY
 
     Options may be granted only to non-employee Directors of the Company
("Outside Directors"). An Outside Director who has been granted an Option may,
if he or she is otherwise eligible, be granted an additional Option or Options
under the 1994 Plan.
 
GRANT AND EXERCISE OF OPTION
 
     The Directors' Plan provides that each person who first becomes a
non-employee director of the Company after the effective date of the Directors'
Plan, will be granted a nonstatutory stock option to
 
                                       10
<PAGE>   14
 
purchase 30,000 shares of Common Stock (the "First Option") on the date on which
the optionee first becomes a non-employee director of the Company. Thereafter,
on the date of each Annual Meeting of the Company's shareholders at which
non-employee directors are elected to the Board, each person so elected
(including directors who were not eligible for a First Option) shall be granted
an additional option to purchase 7,500 shares of Common Stock (a "Subsequent
Option") if he or she shall have served on the Company's Board of Directors for
at least six months prior to the date of such Annual Meeting. The Directors'
Plan provides that the maximum number of shares for which options may be granted
under the Directors' Plan is 150,000 (the "Pool"). However, the Directors' Plan
does not specify a maximum or minimum number of shares for which options may be
granted to any one non-employee director so long as the total number of shares
so granted does not exceed the Pool. No option granted under the Directors' Plan
is transferable by the optionee other than by will or the laws of descent or
distribution or pursuant to a qualified domestic relations order, and each
option is exercisable, during the lifetime of the optionee, only by such
optionee or permitted transferee.
 
     The Directors' Plan provides that the First Option granted thereunder shall
become exercisable in installments as to 25% of the total number of shares
subject to the First Option on each of the first, second, third and fourth
anniversaries of the date of grant of the First Option; and each Subsequent
Option shall become exercisable in full on the first anniversary of the date of
grant of that Subsequent Option. The options will remain exercisable for up to
ninety (90) days following the optionee's termination of service as a director
of the Company, unless such termination is a result of death, in which case the
options will remain exercisable for a six-month period, or disability, in which
case the options will remain exercisable for a six-month period (or such other
period not exceeding twelve months as is determined by the Board).
 
EXERCISE PRICE AND TERM
 
     The exercise price of all stock options granted under the Directors' Plan
shall be equal to 100% of the fair market value of a share of the Company's
Common Stock on the date of grant of the option. Fair market value shall be
determined by the Company's Board; provided, however, that where there is a
public market for the Common Stock, the fair market value per share shall be the
mean of the bid and asked prices of the Common Stock in the over-the-counter
market on the date of grant, as reported in The Wall Street Journal or, in the
event the Common Stock is traded on the Nasdaq Stock Market or listed on a stock
exchange, the fair market value per share shall be the closing price on such
system or exchange on the date of grant of the Option, as reported in The Wall
Street Journal. Options granted under the Directors' Plan have a term of ten
years.
 
MERGER OR SALE OF ASSETS
 
     The Directors' Plan provides that, in the event of the dissolution or
liquidation of the Company, a merger of the Company with or into another
corporation in which the Company is not the surviving corporation, a sale of all
or substantially all of the Company's assets, or any other capital
reorganization in which more than 50% of the shares of the Company entitled to
vote are exchanged, the Company shall give to each non-employee director either
(i) a reasonable time within which to exercise the option in its entirety
(including as to shares which would not otherwise be exercisable) prior to the
effectiveness of any such transaction at the end of which time the option shall
terminate, or (ii) the right to exercise the option in its entirety (or receive
a substitute option with comparable terms) as to an equivalent number of shares
of stock of the corporation succeeding the Company or acquiring its business by
reason of any such transaction.
 
AMENDMENT AND TERMINATION OF THE DIRECTORS' OPTION PLAN
 
     The Board of Directors may amend or terminate the Directors' Plan, provided
that, to the extent necessary and desirable to comply with Rule 16b-3 under the
Exchange Act (or any other applicable law or regulation) the Company shall
obtain approval of the stockholders to such amendments to the extent required by
such law or regulation. The provisions regarding the grant of options under the
Directors' Plan may be amended only once in any six month period, other than to
comport with changes in the Code, the Employee Retirement Income Security Act of
1974, as amended, or the rules thereunder.
 
     If not terminated earlier, the Directors' Plan will terminate in December
2005.
 
                                       11
<PAGE>   15
 
TAX
 
     The federal income tax consequences of participation in the Directors' Plan
are the same as apply to optionee's who receive nonstatutory stock options under
the Company's 1994 Stock Plan, as described above under Proposal No. 2.
 
REQUIRED VOTE
 
     The approval of the amendment to the Directors' Plan to increase the number
of shares reserved for issuance thereunder by 100,000 shares requires the
affirmative vote of the holders of a majority of the shares of the Company's
Common Stock present at the Annual Meeting in person or by proxy and entitled to
vote.
 
RECOMMENDATION OF THE BOARD OF DIRECTORS
 
     The Board of Directors recommends a vote FOR the approval of the amendment
to the Directors' Plan and the reservation of shares for issuance thereunder.
The effect of an abstention is the same as that of a vote against the approval
of the adoption of the amendment to the Directors' Plan.
 
                                       12
<PAGE>   16
 
          ------------------------------------------------------------
 
                                 PROPOSAL NO. 4
 
                     APPROVAL OF AMENDMENT TO 1995 EMPLOYEE
                              STOCK PURCHASE PLAN
 
          ------------------------------------------------------------
 
     At the Annual Meeting, the Company's stockholders are being asked to
approve an amendment to the Company's 1995 Employee Stock Purchase Plan (the
"Purchase Plan") to increase the number of shares of Common Stock reserved for
issuance thereunder by 400,000 shares to an aggregate of 500,000 shares. GENERAL
 
     The Purchase Plan was adopted by the Board of Directors in December 1995
and approved by the stockholders in January 1996. The Purchase Plan is designed
to allow eligible employees (including officers and employee directors) of the
Company and participating subsidiaries to purchase shares of Common Stock, at
semi-annual intervals, through their periodic payroll deductions under the
Purchase Plan. A total of 100,000 shares of Common Stock have been reserved for
this purpose. In February 1998, the Board of Directors approved an amendment to
the Purchase Plan to increase the number of shares of Common Stock reserved for
issuance thereunder by 400,000 shares to an aggregate of 500,000 shares, for
which stockholder approval is requested.
 
     The Purchase Plan is implemented through a series of successive offering
periods, each with a maximum duration of 24 months. Each offering period is
comprised of four purchase periods, each with a maximum duration of six months.
The current offering period began December 1, 1997 and will end on November 30,
1999.
 
     The Purchase Plan is intended to qualify as an "Employee Stock Purchase
Plan" under Section 423 of the Code. The Purchase Plan is not a qualified
deferred compensation plan under Section 401(a) of the Code, and is not subject
to the provisions of the Employee Retirement Income Security Act of 1974, as
amended. The provisions of the Purchase Plan shall, accordingly, be construed so
as to extend and limit participation in a manner consistent with the
requirements of that section of the Code.
 
     As of February 27, 1998, 53,853 shares had been issued pursuant to the
purchase of shares issued under such plan and 46,147 shares remained available
for future purchases. As of February 27, 1998, the aggregate fair market value
of shares subject to outstanding options under the Purchase Plan was
$190,356.38, based upon the closing price of the Common Stock as reported on The
Nasdaq Stock Market on such date. Since the inception of the Purchase Plan, the
Company's executive officers have purchased 15,653 shares under the Purchase
Plan and other employees of the Company have purchased 38,200 shares under the
Purchase Plan.
 
PURPOSE
 
     The purpose of the Purchase Plan is to provide employees of the Company and
its Designated Subsidiaries with an opportunity to purchase Common Stock of the
Company.
 
ADMINISTRATION
 
     The Purchase Plan is administered by the Compensation Committee of the
Board of Directors. All questions of interpretation or application of the
Purchase Plan are determined by the committee.
 
ELIGIBILITY
 
     Employees (including officers and employee directors) who are employed for
at least 20 hours per week and more than five months per calendar year with the
Company (including subsidiaries of the Company approved by the Board) are
eligible to participate in an offering under the Purchase Plan, subject to
certain limitations imposed by Section 423(b) of the Internal Revenue Code and
limitations on stock ownership as set
 
                                       13
<PAGE>   17
 
forth in the Purchase Plan. Eligible employees become participants in the
Purchase Plan by filing with the payroll office of the Company a stock purchase
agreement and a payroll deduction authorization form prior to the date an
eligible employee first commences participation in the offering period in
effect.
 
GRANT AND EXERCISE OF PURCHASE RIGHT
 
     At the beginning of an offering period, each participant is granted a right
to purchase up to that number of shares determined by dividing such employee's
payroll deductions accumulated prior to a purchase period in the offering period
and retained in the participant's account as of the end of the purchase period
by eighty-five percent (85%) of the lower of (i) the fair market value of a
share of the Company's Common Stock at the date an eligible employee first
commences participation in the offering period in effect (on the start date of
the offering period) or (ii) the fair market value of a share of the Company's
Common Stock at the end of the purchase period; provided that the maximum number
of shares an Employee may purchase during each Offering Period may not exceed
$12,500 divided by the fair market value of a share of the Company's Common
Stock on the date such employee commences participation in the offering period;
and provided further that such purchases are subject to the limitations set
forth below. No employee may be granted a purchase right under the Purchase Plan
(i) if, immediately after the grant, such employee (or any other person whose
stock would be attributed to such employee pursuant to Section 424(d) of the
Code) would own stock and/or hold outstanding options to purchase stock
possessing five percent or more of the total combined voting power or value of
all classes of stock of the Company or of any subsidiary of the Company, or (ii)
if such purchase right, when aggregated with his or her rights to purchase stock
under any other purchase right granted under all employee stock purchase plans
(within the meaning of Section 423 of the Code) of the Company and its
subsidiaries, would otherwise permit such employee to purchase more than $25,000
worth of stock of the Company (determined at the time such rights are granted)
for each calendar year in which such rights are outstanding at any time.
 
     The Company may make a pro rata reduction in the number of shares subject
to purchase rights if the total number of shares that would otherwise be subject
to purchase rights exceeds the number of remaining available shares in the
Purchase Plan. Unless an employee withdraws his or her participation in the
Purchase Plan by giving written notice to the Company of his or her election to
withdraw all accumulated payroll deductions prior to the end of a purchase
period, the employee's purchase right for the purchase of shares will be
exercised automatically at the end of the purchase period, and the maximum
number of full shares subject to purchase right that are purchasable with the
accumulated payroll deductions in his or her account will be purchased at the
applicable purchase price determined as provided below.
 
     During his or her lifetime, a participant's option to purchase shares under
the Purchase Plan is exercisable only by him or her. However, a participant may
file a written designation of a beneficiary who is (i) to receive any shares and
cash, if any, from the participant's account under the Purchase Plan in the
event of such participant's death subsequent to the end of an Offering Period
but prior to delivery to him or her of such shares and cash, and (ii) to receive
any cash from the participant's account under the Purchase Plan in the event of
such participant's death prior to the Purchase Date of the Offering Period. If a
participant is married and the designated beneficiary is not the spouse, spousal
consent shall be required for such designation to be effective.
 
PURCHASE PRICE
 
     The purchase price per share at which shares are sold to participating
employees under the Purchase Plan is eighty-five percent of the lower of (i) the
fair market value of a share of the Company's Common Stock at the date an
eligible employee first commences participation in the offering period in effect
(generally the start date of the offering period) or (ii) the fair market value
of a share of the Company's Common Stock at the end of the purchase period. The
fair market value of the Common Stock on a given date shall be the closing
selling price if the Common Stock is listed on a stock exchange or on the Nasdaq
Stock Market.
 
                                       14
<PAGE>   18
 
PAYROLL DEDUCTIONS
 
     The purchase price of the shares to be acquired under the Purchase Plan is
accumulated by payroll deductions over the offering period. The deductions may
not be less than one percent (1%) of a participant's aggregate compensation
during the offering period, nor more than maximum of fifteen percent (15%). A
participant may discontinue his or her participation in the Purchase Plan or, on
one occasion only during the purchase period, may increase or reduce his or her
rate of payroll deductions. Payroll deductions for a participant shall commence
on the first payroll following the date an eligible employee first commences
participation in the offering period in effect and shall (unless sooner
terminated by the participant) continue through the pay day ending with or
immediately prior to the last day of the offering period.
 
TERMINATION OF EMPLOYMENT
 
     Termination of a participant's employment for any reason, including
retirement or death, or the failure of the participant to remain in the
continuous employ of the Company for at least 20 hours per week during the
applicable offering period, terminates his or her purchase right and his or her
participation in the Purchase Plan immediately. In such event, the payroll
deductions credited to the participant's account will be immediately refunded.
 
CAPITAL CHANGES
 
     In the event any change is made in the Company's capitalization, such as a
stock split or stock dividend, that results in an increase or decrease in the
number of shares of Common Stock outstanding without receipt of consideration by
the Company, appropriate adjustment will be made to the number of shares of
Common Stock covered by each unexercised purchase right, the number of shares of
Common Stock that have been authorized for issuance under the Purchase Plan but
have not yet been placed under a purchase right, and the price per share of
Common Stock covered by each unexercised purchase right.
 
     In the event of a proposed dissolution or liquidation of the Company, the
offering period will terminate immediately prior to the consummation of such
proposed action, unless otherwise provided by the Board. In the event of a
proposed sale of all or substantially all of the assets of the Company, or the
merger of the Company with or into another corporation, each option under the
Purchase Plan will be assumed or an equivalent option will be substituted by
such successor corporation, unless the Company's Board determines to shorten the
offering period then in progress by setting a new purchase date.
 
AMENDMENT AND TERMINATION OF THE PLAN
 
     The Board of Directors may at any time terminate or amend the Purchase
Plan. No such termination may affect options previously granted, nor may an
amendment make any change in any option theretofore granted which adversely
affects the rights of any participant. In addition, to the extent necessary to
comply with Rule 16b-3 under the Exchange Act, or under Section 423 of the Code,
the Company must obtain stockholder approval in such a manner and to such a
degree as required under such laws.
 
     The Purchase Plan will continue in effect until January 2015 unless sooner
terminated by the Board.
 
TAX INFORMATION
 
     The Purchase Plan, and the right of participants to make purchases
thereunder, are intended to qualify under the provisions of Sections 421 and 423
of the Code. Under these provisions, no taxable income will be recognized by a
participant until the shares purchased under the Plan are sold or otherwise
disposed of. Upon sale or other disposition of the shares, the participant will
generally be subject to tax and the amount of the taxable income will depend
upon the holding period. If the shares are sold or otherwise disposed of more
than two years from the first day of the offering period and one year after the
purchase date, the participant will recognize ordinary income measured as the
lesser of (a) the excess of the fair market value of the shares at the time of
such sale or disposition over the purchase price, or (b) an amount equal to 15%
of the fair market value of the shares as of the first day of the offering
period. Any additional gain or loss will be treated as
 
                                       15
<PAGE>   19
 
long-term capital gain or loss. For individual taxpayers, the current U.S.
federal income tax rate on long-term capital gains is alternatively 28% (in the
case of shares held more than one year but less than 18 months after exercise),
and 20% (in the case of shares held more than 18 months after exercise), whereas
the maximum rate on other income is 39.6%. If the shares are sold or otherwise
disposed of before the expiration of these holding periods, the participant will
recognize ordinary income generally measured as the excess, if any, of the fair
market value of the shares on the date the shares are purchased over the
purchase price. Any additional gain or loss on such sale or disposition will be
long-term or short-term capital gain or loss, depending on the holding period.
The Company is not entitled to a deduction for amounts taxed as ordinary income
or capital gain to a participant except to the extent of ordinary income
recognized by participants upon a sale or disposition of shares prior to the
expiration of the holding periods described above.
 
     The foregoing is only a brief summary of the effect of federal income
taxation upon the participant and the Company with respect to the shares
purchased under the Purchase Plan. Reference should be made to the applicable
provisions of the Internal Revenue Code. In addition, the summary does not
discuss the tax consequences of a participant's death or the income tax laws of
any state or foreign country in which the participant may reside. Holders of
purchase rights should consult their own tax advisors with respect to the tax
consequences of participation in the Purchase Plan for their particular
situations.
 
REQUIRED VOTE
 
     The approval of the amendment to the Purchase Plan to increase the number
of shares reserved for issuance thereunder by 400,000 shares requires the
affirmative vote of the holders of a majority of the shares of the Company's
Common Stock present at the Annual Meeting in person or by proxy and entitled to
vote. RECOMMENDATION OF THE BOARD OF DIRECTORS
 
     The Board of Directors recommends a vote FOR the approval of the amendment
to the Purchase Plan and the reservation of shares for issuance thereunder. The
effect of an abstention is the same as that of a vote against the approval of
the adoption of the amendment to the Purchase Plan.
          ------------------------------------------------------------
 
                                 PROPOSAL NO. 5
 
                          RATIFICATION OF SELECTION OF
                              INDEPENDENT AUDITORS
 
          ------------------------------------------------------------
 
     The firm of Ernst & Young LLP served as independent auditors for the
Company for the year ended December 31, 1997. The Board of Directors has
selected that firm to continue in this capacity for the current fiscal year. The
Company is asking the stockholders to ratify the selection by the Board of
Directors of Ernst & Young LLP, as independent auditors, to audit the accounts
and records of the Company for the year ending December 31, 1998, and to perform
other appropriate services. A representative of Ernst & Young LLP is expected to
be present at the Annual Meeting to respond to stockholders' questions, and if
he or she so desires, will be given an opportunity to make a brief statement.
 
     The Board of Directors recommends a vote IN FAVOR OF the ratification of
the selection of Ernst & Young LLP. In the event that a majority of the shares
voted at the Annual Meeting do not vote for the ratification, the Board of
Directors will reconsider such selection. Under all circumstances, the Board of
Directors retains the corporate authority to change the auditors at a later
date.
 
                                       16
<PAGE>   20
 
                 EXECUTIVE COMPENSATION AND RELATED INFORMATION
 
REPORT OF THE COMPENSATION COMMITTEE
 
     The Compensation Committee of the Board of Directors has general
responsibility for establishing the compensation payable to the Company's
executive officers and has the sole and exclusive authority to administer the
Company's 1994 Stock Plan under which grants may be made to such individuals.
 
  General Compensation Policy
 
     Under the supervision of the Compensation Committee, the Company's
compensation policy is designed to attract and retain qualified key executives
critical to the Company's growth and long-term success. It is the objective of
the Compensation Committee to have a portion of each executive's compensation
contingent upon the Company's performance as well as upon the individual's
personal performance. Accordingly, each executive officer's compensation package
is comprised of three elements: (i) base salary which reflects individual
performance and expertise, (ii) variable bonus awards payable in cash and tied
to the achievement of certain performance goals which the Compensation Committee
establishes from time to time for the Company or the individual and (iii)
long-term stock-based incentive awards which are designed to strengthen the
mutuality of interests between the executive officers and the Company's
stockholders.
 
     The summary below describes in more detail the factors which the
Compensation Committee considers in establishing each of the three primary
components of the compensation package provided the executive officers.
 
    Base Salary
 
     The level of base salary is established primarily on the basis of the
individual's qualifications and relevant experience, the strategic goals for
which he or she has responsibility, the compensation levels at companies that
compete with the Company for business and executive talent, and the incentives
necessary to attract and retain qualified management. Base salary is adjusted in
January of each year to take into account the individual's performance and to
maintain a competitive salary structure. Company performance does not play a
significant role in the determination of base salary.
 
    Cash-Based Incentive Compensation
 
     Cash bonuses are awarded to executive officers on the basis of their
success in achieving designated individual goals and the Company's success in
achieving specific company-wide goals, such as product development milestones
and stock price appreciation.
 
    Long-Term Incentive Compensation
 
     The Company has utilized its stock option plans to provide executives and
other key employees with incentives to maximize long-term stockholder values.
Awards under the Company's option plan by the Compensation Committee take the
form of stock options designed to give the recipient a significant equity stake
in the Company and thereby closely align his or her interests with those of the
Company's stockholders. Factors considered in making such awards include the
individual's position in the Company, his or her performance and
responsibilities, and internal comparability considerations. In addition, the
Compensation Committee has established certain general guidelines in making
option grants to the executive officers in an attempt to target a fixed number
of unvested option shares based upon each individual's position with the Company
and his or her existing holdings of unvested options. However, the Compensation
Committee does not adhere strictly to these guidelines and will vary the size of
the option grant made to each executive officer as it believes the circumstances
warrant.
 
     Each option grant allows the officer to acquire shares of Common Stock at a
fixed price per share (the fair market value on the date of grant) over a
specified period of time (up to 10 years). The options typically vest in
periodic installments over a four-year period, contingent upon the executive
officer's continued
 
                                       17
<PAGE>   21
 
employment with the Company. Accordingly, the option will provide a return to
the executive officer only if he or she remains in the Company's service, and
then only if the market price of the Common Stock appreciates over the option
term.
 
     CEO Compensation
 
     In setting the compensation payable during fiscal 1997 to the Company's
Chief Executive Officer, Thomas G. Wiggans, the Committee used the same factors
as described above for the executive officers. The Compensation Committee
reviewed Mr. Wiggans' compensation relative to industry comparables and his
performance over the last twelve (12) months in achieving the Company goals. As
a result of this review, in January 1997, Mr. Wiggans received a stock option
grant of 100,000 shares, as part of a number of grants made to the Company's
employees. There were no bonuses given to the Company's executive officers or
other employees during fiscal 1997. Mr. Wiggans annual base salary was set in
March 1996 at $280,000 with no change in salary made for 1997.
 
                            Compensation Committee:
                                  John C. Kane
                             Joseph J. Ruvane, Jr.
 
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
 
     The members of the Compensation Committee are John C. Kane and Joseph J.
Ruvane, Jr. In addition, Brian Dovey served on the Committee during 1997. None
of these individuals was at any time during the year ended December 31, 1997 or
at any other time an officer or employee of the Company.
 
     No executive officer of the Company serves as a member of the board of
directors or compensation committee of any entity that has one or more executive
officers serving as a member of the Company's Board of Directors or Compensation
Committee.
 
                                       18
<PAGE>   22
 
STOCK PERFORMANCE GRAPH
 
     The following graph shows a comparison of cumulative total stockholder
returns for the Company, the NASDAQ Composite Index, and the Nasdaq
Pharmaceutical Index for the period commencing January 31, 1996, the date of the
Company's initial public offering, to the last day of the Company's fiscal year
ended December 31, 1997.
 
<TABLE>
<CAPTION>
        Measurement Period                                                   Pharmaceutical
      (Fiscal Year Covered)            Connective            Nasdaq               Index
<S>                                 <C>                 <C>                 <C>
2/1/96                                     100                 100                 100
3/29/96                                     71                 103                  95
6/28/96                                     89                 112                  92
9/30/96                                     78                 116                  94
12/31/96                                    73                 121                  91
3/31/97                                     66                 115                  87
6/30/97                                     62                 136                  94
9/30/97                                     32                 159                 105
12/31/97                                    27                 149                  94
</TABLE>
 
     Notwithstanding anything to the contrary set forth in any of the Company's
previous filings under the Securities Act of 1933, as amended, or the Securities
Exchange Act of 1934, as amended, which might incorporate future filings made by
the Company under those statutes, the preceding Compensation Committee Report on
Executive Compensation and Performance Graph are not to be incorporated by
reference into any of those previous filings; nor is such report or graph to be
incorporated by reference into any future filings which the Company may make
under those statutes.
 
                                       19
<PAGE>   23
 
                 SUMMARY OF CASH AND CERTAIN OTHER COMPENSATION
 
EXECUTIVE COMPENSATION
 
     The following table sets forth certain compensation paid by the Company
during the fiscal years ended December 31, 1997, December 31, 1996 and December
31, 1995 to the Company's Chief Executive Officer and the Company's four other
most highly compensated executive officers during fiscal 1997 and a former
executive officer of the Company (collectively, the "Named Executive Officers"):
 
                           SUMMARY COMPENSATION TABLE
 
<TABLE>
<CAPTION>
                                                                            LONG-TERM
                                                                           COMPENSATION
                                     FISCAL YEAR    ANNUAL COMPENSATION     SECURITIES
                                        ENDED       --------------------    UNDERLYING       ALL OTHER
    NAME AND PRINCIPAL POSITION      DECEMBER 31,   SALARY($)   BONUS($)    OPTIONS(#)    COMPENSATION($)
    ---------------------------      ------------   ---------   --------   ------------   ---------------
<S>                                  <C>            <C>         <C>        <C>            <C>
Thomas G. Wiggans..................    1997         $280,000    $      0     100,000         $ 43,751(1)
  President and Chief                  1996         $270,833    $120,000           0         $ 79,972(2)
     Executive Officer                 1995         $225,000    $ 20,000      78,161         $ 27,199(3)
W. Scott Harkonen..................    1997         $219,000    $      0      25,000         $  1,350(4)
  Senior Vice President, Product       1996         $210,000    $ 26,000           0         $  1,288(4)
     Development and Operations        1995         $ 70,000    $ 40,782      84,312         $ 20,262(5)
Richard J. Hammel..................    1997         $181,000    $      0      20,000         $  1,797(4)
  Vice President, Commercial           1996         $165,000    $ 17,500           0         $  1,613(4)
     Development                       1995         $ 55,000    $ 10,000      62,953         $      0
David A. Lowin.....................    1997         $181,000    $      0      18,000         $    636(4)
  Vice President,                      1996         $172,500    $ 30,000           0         $    598(4)
     Intellectual Property and         1995         $148,542    $ 25,000      31,476         $      0
     Chief Patent Counsel
Ernst Rinderknecht.................    1997         $172,115    $      0      13,000         $  3,049(6)
  Vice President, Process Science      1996         $159,000    $ 12,000           0         $  2,858(7)
     and Manufacturing                 1995         $152,798    $ 26,314      28,104         $  1,314(8)
Cynthia M. Butitta(9)..............    1997         $139,610    $      0      12,000         $143,796(10)
  Formerly, Vice President,            1996         $175,000    $ 20,000           0         $    612(4)
     Finance and Administration        1995         $ 14,133    $      0      55,319         $ 25,000(11)
     and Chief Financial Officer
</TABLE>
 
- ---------------
 
(1)  Represents term life insurance premiums of $3,275 paid by the Company for
     such officer's benefit, airfare for spouse of $2,232 and debt forgiveness
     on a loan of $38,244. See "Certain Relationships and Related Transactions."
 
(2)  Represents term life insurance premiums of $3,163 paid by the Company for
     such officer's benefit and debt forgiveness on a loan of $76,809. See
     "Certain Relationships and Related Transactions."
 
(3)  Represents term life insurance premiums of $1,240 paid by the Company for
     such officer's benefit, $253 for taxes paid in conjunction with a bonus and
     $25,706 for relocation expenses.
 
(4)  Represents term life insurance premiums paid by the Company for such
     officer's benefit.
 
(5)  Represents term life insurance premiums of $1,350 paid by the Company for
     such officer's benefit and relocation and moving expenses of $20,262.
 
(6)  Represents term life insurance premiums of $1,735 paid by the Company for
     such officer's benefit and reimbursement for disability insurance paid by
     the executive of $1,314.
 
(7)  Represents term life insurance premiums of $1,544 paid by the Company for
     such officer's benefit and reimbursement for disability insurance paid by
     the executive of $1,314.
 
(8)  Represents reimbursement for disability insurance paid by the executive.
 
                                       20
<PAGE>   24
 
(9)  Resigned from the Company in September 1997, but has been retained as a
     consultant through March 1998. See "Certain Relationships and Related
     Transactions."
 
(10) Represents term life insurance premiums of $504 paid by the Company for
     such officer's benefit, a lump sum severance payment of $90,500 and
     consulting fees of $52,792.
 
(11) Represents bonus upon hire.
 
                       OPTION GRANTS IN LAST FISCAL YEAR
 
     The following table provides certain information with respect to stock
options granted to the Named Executive Officers in the last fiscal year. In
addition, as required by Securities and Exchange Commission rules, the table
sets forth the hypothetical gains that would exist for the options based on
assumed rates of annual compound stock price appreciation during the option
term.
 
<TABLE>
<CAPTION>
                                                                                        POTENTIAL REALIZABLE VALUE
                           NUMBER OF                                                    AT ASSUMED ANNUAL RATES OF
                             SHARES     PERCENTAGE OF                                  STOCK PRICE APPRECIATION FOR
                           UNDERLYING   TOTAL OPTIONS                                         OPTION TERM(2)
                            OPTIONS      GRANTED TO     EXERCISE PRICE   EXPIRATION   ------------------------------
          NAME             GRANTED(1)     EMPLOYEES       PER SHARE         DATE       0%       5%           10%
          ----             ----------   -------------   --------------   ----------   ----   ---------   -----------
<S>                        <C>          <C>             <C>              <C>          <C>    <C>         <C>
Thomas G. Wiggans........   100,000         14.3%           $7.125        1/28/07     $ 0    $448,087    $1,135,541
Richard J. Hammel........    20,000          2.9%           $7.125        1/28/07     $ 0    $ 89,618    $  227,108
W. Scott Harkonen........    25,000          3.6%           $7.125        1/28/07     $ 0    $112,022    $  283,885
David A. Lowin...........    18,000          2.6%           $7.125        1/28/07     $ 0    $ 80,656    $  204,397
Ernst Rinderknecht.......    13,000          1.7%           $7.125        1/28/07     $ 0    $ 58,251    $  147,620
Cynthia M. Butitta(3)....    12,000          1.7%           $7.125        1/28/07     $ 0    $ 53,770    $  136,265
</TABLE>
 
- ---------------
 
(1) These stock options, which were granted under the 1994 Stock Plan, generally
    become exercisable at a rate of 1/4 of the shares of Common Stock subject to
    the option at the end of the first twelve month period after the date of
    grant and 1/16 of the shares of Common Stock subject to the option at the
    end of each quarter thereafter, as long as the optionee remains an employee
    with, consultant to, or director of the Company.
 
(2) The 5% and 10% assumed annual rates of compounded stock price appreciation
    are mandated by the Securities and Exchange Commission. There is no
    assurance provided to any executive officer or any other holder of the
    Company's securities that the actual stock price appreciation over the
    10-year option term will be at the assumed 5% and 10% levels or at any other
    defined level. Unless the market price of the Common Stock appreciates over
    the option term, no value will be realized from the option grants made to
    the executive officers.
 
(3) Resigned as an executive officer of the Company in September 1997. See
    "Certain Relationships and Related Transactions."
 
                                       21
<PAGE>   25
 
                AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR
                       AND FISCAL YEAR-END OPTION VALUES
 
     The following table sets forth information for the Named Executive Officers
with respect to exercises of options to purchase common stock in the fiscal year
ended December 31, 1997.
 
<TABLE>
<CAPTION>
                                                                  NUMBER OF SHARES            VALUE OF UNEXERCISED
                                                               UNDERLYING UNEXERCISED         IN-THE-MONEY OPTIONS
                                                             OPTIONS AT FISCAL YEAR END       AT FISCAL YEAR END(2)
                       SHARES ACQUIRED                       ---------------------------   ---------------------------
        NAME           ON EXERCISE(1)    VALUE REALIZED(1)   EXERCISABLE   UNEXERCISABLE   EXERCISABLE   UNEXERCISABLE
        ----           ---------------   -----------------   -----------   -------------   -----------   -------------
<S>                    <C>               <C>                 <C>           <C>             <C>           <C>
Thomas G. Wiggans....      67,981            $327,040          11,179         166,982       $ 29,268       $175,372
W. Scott Harkonen....           0            $      0          46,840          62,472       $122,636       $ 98,109
Richard J. Hammel....           0            $      0          34,942          48,011       $ 91,485       $ 73,338
David A. Lowin.......           0            $      0          17,049          32,427       $ 44,638       $ 37,773
Ernst Rinderknecht...           0            $      0          15,223          25,881       $ 39,857       $ 33,725
Cynthia M.
  Butitta(3).........      10,000            $  3,386          29,228          48,091       $ 24,525       $ 30,284
</TABLE>
 
- ---------------
(1) Shares acquired at exercise were not necessarily sold. The value realized
    upon exercise is based upon the closing fair market value of the Company's
    Common Stock on the date of exercise.
 
(2) Based on the closing price of the Company's Common Stock on December 31,
    1997 as reported on the NASDAQ National Market ($3.06 per share), minus the
    per share exercise price, multiplied by the number of shares underlying the
    option.
 
(3) Resigned from the Company in September 1997 but has been retained as a
    consultant through March 1998.
 
                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
 
     In June 1994, the Company entered into an employment agreement with Thomas
G. Wiggans, the President and Chief Executive Officer of the Company. Pursuant
to such agreement, Mr. Wiggans receives an annual base salary of $225,000, which
subject to annual review, was raised in March 1996 to $280,000. In consideration
of Mr. Wiggans' attainment of corporate goals and achievement of key milestones,
the Compensation Committee awarded him a cash bonus of $80,000 in February 1996,
upon the successful completion of the Company's initial public offering and a
cash bonus of $40,000 in January 1997 for the achievement of the Company's
corporate goals for 1996. In addition, Mr. Wiggans acquired 146,142 shares of
Common Stock pursuant to a restricted stock purchase agreement in June 1994.
1/10(th) of the shares were released from the Company's repurchase option in
December 1994 and 1/60(th) are released each month thereafter. The employment
agreement also entitles Mr. Wiggans to receive continuation of salary and
benefits and continuation of vesting with respect to all of the Common Stock
held by Mr. Wiggans for nine months following the termination of his employment
from the Company other than for cause, and to the payment of premiums on a life
insurance policy in the amount of $1,000,000. The employment agreement also
provided for reimbursement by the Company of up to $110,000 for combined actual
relocation and housing expenses.
 
     Additionally, the Company and Mr. Wiggans have entered into two
interest-bearing loan agreements for up to $108,000 and for $225,000,
respectively, both of which are secured by shares of Common Stock held by Mr.
Wiggans. Amounts drawn on the $108,000 loan are due on the third anniversary of
the date of each draw. The principal balance owed to the Company under the
$108,000 loan was $72,000, which was also the largest aggregate amount that was
outstanding, payable under two $36,000 promissory notes with interest at 5.63%
and 5.73% per annum, respectively. These two loans were forgiven in 1996 for a
total of $76,809, which includes principal plus interest. The remaining $36,000
related to the original loan of $108,000, payable under a promissory note with
interest at 6.15% per annum, was loaned in July 1996 and forgiven in July 1997
for a total forgiveness of principal and accrued interest of $38,244. The
$225,000 loan was amended and restated in July 1996; the new principal amount of
the loan is $256,401.10, and the loan bears interest at a rate of 6.74% per
annum. Under the restated terms, a $50,000 principal payment plus interest
accrued to date was and is due and payable on each of July 31, 1997, July 31,
1998, July 31, 1999, July 31, 2000 and July 31, 2001. The current balance owed
to the Company under this loan at December 31, 1997 was $211,215. The balance of
the
                                       22
<PAGE>   26
 
principal amount outstanding plus all accrued interest is due and payable on
July 31, 2001. The largest amount outstanding under this note in 1997 was
$311,926.20.
 
     In December 1995, the Company entered into a Master Bridge Loan Agreement
with certain stockholders of the Company (the "Bridge Investors"), pursuant to
which such Bridge Investors severally and unconditionally agreed to lend up to a
maximum aggregate total of $5 million to the Company. No loans were made under
this Agreement, and the Company's ability to call for any loans expired upon the
closing of the Company's initial public offering in February 1996. In
consideration for this commitment, in February 1996, the Company delivered to
each such Bridge Investor a five-year warrant to purchase a number of shares of
Common Stock equal to (a) the original face principal amount of such Bridge
Investor's commitment times (b) 5%, divided by (c) $11.00, the price per share
of the initial public offering. The exercise price of the warrants is $11.00 per
share. The following five percent stockholders of the Company were Bridge
Investors: Sierra Ventures IV, L.P., Sprout Capital VII, L.P., and Domain
Partners III, L.P. See "Principal Stockholders." Brian H. Dovey, a general
partner of the general partner of Domain Partners III, L.P., is a director of
the Company.
 
     In October 1995, the Company entered into a consulting agreement with G.
Kirk Raab, the Chairman of the Company's Board of Directors. See "Proposal No.
1: Election of Directors -- Board of Directors Committees; Compensation of
Directors and Other Information."
 
     In March 1996, the Board authorized the Company to enter into individual
agreements with each of the Company's directors and executive officers to
provide in the event of a merger or acquisition of the Company and another
entity, all stock options held by such person will automatically vest in full
(i) unless the Company is the surviving entity after such transaction and the
Company's stockholders immediately prior to such transaction own a majority of
the outstanding securities of the surviving entity or (ii) if, as the result of
such transaction, the officer or director's position with the Company is
terminated or his or her responsibilities are adversely changed or reduced
without his or her written consent. Subsequent to March 1996, each new director
and executive officer has entered into the same agreement.
 
     In December 1996, the Company acquired the exclusive U.S. and Canadian
rights to Ridaura(R) (auranofin), a disease modifying antirheumatic drug, from
SmithKline Beecham Corporation and related entities ("SmithKline"). As
consideration to SmithKline, the Company provided a $3 million upfront cash
payment, which was paid in January 1997, a non-interest bearing $11.0 million
promissory note, payable in two installments in January 1998 and January 1999
(of $6.0 million and $5.0 million, respectively) and secured by the intellectual
property acquired from SmithKline, 637,733 shares of the Company's common stock
with a guaranteed value of $9.0 million on December 31, 1997, and an obligation
to pay up to $6.0 million in sales-based royalty payments, for an aggregate
purchase price of up to $29.0 million. The $11.0 million promissory note was
discounted at inception using an imputed interest rate of 11% and future imputed
interest expense attributable to these payments is $1.6 million. In November
1997, this note was amended to defer the initial $6.0 million payment,
originally due in January 1998, to April 1998 ($1.0 million), October 1998 ($1.5
million) and January 1999 ($3.5 million). The amendment also provides that
Connetics will pay interest on the unpaid principal from January 1998 to January
1999 at a rate of prime plus two percent (2%). Under a related Transitional
Services Agreement, customer orders and distribution for the product were
managed by SmithKline through 1997 with no additional consideration for
performing such services. The parties also entered into a Supply Agreement,
under which SmithKline will manufacture and supply Ridaura (in final finished
package form) to the Company for an initial term of five years. As a result of
the share issuance, SmithKline became the beneficial owner of more than five
percent (5%) of the Company's Common Stock. See "Common Stock Ownership of
Certain Beneficial Owners and Management."
 
     In December 1997, the Company entered into an Omnibus Amendment with
SmithKline, pursuant to which several changes were made to the Company's payment
obligations to SmithKline. First, the amendment revised the original requirement
that the 637,733 shares of Common Stock issued to SmithKline in December 1996
would be guaranteed to have a minimum value of $9.0 million on December 31,
1997; the shares are now guaranteed to have a minimum value of $8.0 million on
April 1, 1998. Second, if the Company is unable to issue the full number of
shares otherwise issuable to SmithKline on April 1, 1998, the cash value of the
 
                                       23
<PAGE>   27
 
unissuable shares will be added to the Company's obligation to pay up to $6.0
million in sales-based royalty payments owed to SmithKline, and the royalty rate
for Ridaura sales will increase. Third, the promissory note issued to SmithKline
was amended to reduce the October 1998 principal payment to $1,000,000 and to
increase the January 1999 principal payment to $4,000,000. Fourth, in
consideration of the foregoing changes, the Company paid SmithKline $1,000,000
December 31, 1997. See "Common Stock Ownership of Certain Beneficial Owners and
Management."
 
     In May 1997, the Company and a selling stockholder sold an aggregate of
1,936,357 shares of the Company's Common Stock at a price of $6.05 per share to
certain accredited investors in a private placement. The investors also received
warrants to purchase shares of the Company's common stock at an exercise price
of $9.08 per share. As part of this financing, certain directors and five
percent stockholders of the Company purchased shares of Common Stock from the
Company and received warrants as follows: Sprout Capital VII, L.P. and
affiliated entities (1,239,670 shares for an aggregate price of $7,500,004 and
warrants for an additional 619,835 shares), Domain Partners III, L.P. and
affiliated entities (124,651 shares for an aggregate price of $754,138 and
warrants for an additional 62,325 shares), and Alexander E. Barkas, with his
wife Linda Wijcik, (23,710 shares for an aggregate price of $143,446 and
warrants for an additional 11,855 shares). Brian H. Dovey, a general partner of
the general partner of Domain Partners III, L.P., is a director of the Company.
See "Common Stock Ownership of Certain Beneficial Owners and Management."
 
     In September 1997, the Company and Cynthia M. Butitta, former Vice
President of Finance and Administration and Chief Financial Officer, entered
into a separation agreement, pursuant to which the Company accepted Ms.
Butitta's resignation as an employee and officer of the Company and agreed to
pay Ms. Butitta all accrued salary, accrued and unused vacation earned, and six
(6) months of base salary ($90,500) as a severance benefit. Under the agreement,
Ms. Butitta will serve as a consultant to the Company from the date of the
agreement through March 1998 and will receive $15,000 per month as consulting
fees.
 
     In October 1997, the Company and W. Scott Harkonen, the Company's Senior
Vice President of Product Development and Operations, entered into a Secured
Loan Agreement and Security Agreement providing for a loan to Dr. Harkonen of
$100,000, which is secured by 25,000 shares of Common Stock issuable upon the
exercise of vested options held by Dr. Harkonen. The loan bears interest at 8.5%
per annum, compounded annually and at December 31, 1997, $101,462.36 was owed
under the loan (the largest amount outstanding in 1997). All principal and
accrued interest is due and payable on the earliest of (a) October 30, 2000 or
(b) the termination of Dr. Harkonen's employment or consulting relationship with
the Company for any reason.
 
     In December 1997, the Company completed a public offering of 1,750,000
shares of its Common Stock at a purchase price of $3.00 for aggregate gross
proceeds of $5,250,000. In connection with this financing, certain directors and
five percent stockholders of the Company purchased shares of Common Stock from
the Company as follows: Domain Partners III, L.P. and an affiliated entity
(450,000 shares), Alexander E. Barkas, a director of the Company, (70,000
shares), Thomas D. Kiley, a director of the Company, (30,000 shares), and
Amerindo Investment Advisors (1,200,000 shares), who became a five percent
stockholder upon purchasing such shares. See "Common Stock Ownership of Certain
Beneficial Owners and Management." Brian H. Dovey, a general partner of the
general partner of Domain Partners III, L.P., is a director of the Company.
 
     The Company and CORD Logistics, Inc. ("CORD") are currently finalizing a
Distribution Services Agreement, pursuant to which CORD will be appointed the
primary distribution agent in and for the United States, the District of
Columbia and Puerto Rico for the distribution of Ridaura to the Company's direct
customers. Under the agreement, which is expected to have an initial term of
three years, the Company would pay CORD an initial start-up fee of $45,000 for
implementation and will pay monthly fixed fees of $10,500 for system access,
customer service and financial services, in addition to other per order and
fixed fees for distribution, customer services and financial services. CORD is a
subsidiary of Cardinal Health, Inc., of which Mr. Kane (a director of the
company) is President, Chief Operating Officer and a director.
 
     The Company has entered into indemnification agreements with its officers
and directors containing provisions which may require the Company, among other
things, to indemnify its officers and directors against certain liabilities that
may arise by reason of their status or service as officers or directors (other
than liabilities
                                       24
<PAGE>   28
 
arising from willful misconduct of a culpable nature) and to advance their
expenses incurred as a result of any proceeding against them as to which they
could be indemnified.
 
     The Company believes that all of the transactions set forth above were made
on terms no less favorable to the Company than could have been obtained from
unaffiliated third parties. All future transactions, including loans, between
the Company and its officers, directors, principal stockholders and their
affiliates will be approved by a majority of the Board of Directors, including a
majority of the independent and disinterested directors, and will continue to be
on terms no less favorable to the Company than could be obtained from
unaffiliated third parties.
 
                                       25
<PAGE>   29
 
            SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
 
     The members of the Board of Directors, the executive officers of the
Company and persons who hold more than ten percent (10%) of the Company's
outstanding Common Stock are subject to the reporting requirements of Section
16(a) of the Securities Exchange Act of 1934, which requires such individuals to
file reports with respect to their ownership of and transactions in the
Company's securities. Officers, directors and greater than ten percent (10%)
stockholders are required to furnish the Company with copies of all such reports
they file.
 
     Based upon the copies of those reports furnished to the Company and written
representations by persons subject to Section 16(a) that no other reports were
required to be filed, the Company believes that all reporting requirements under
Section 16(a) for the year ended December 31, 1997 were met in a timely manner
by executive officers, Board members and greater than ten percent (10%)
stockholders.
 
                                       26
<PAGE>   30
 
       COMMON STOCK OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT
 
     The following table sets forth certain information known to the Company
with respect to the beneficial ownership of the Company's Common Stock as of
February 27, 1998 by (i) all persons who are beneficial owners of five percent
or more of the Company's Common Stock, (ii) each director and nominee, (iii)
each executive officer of the Company, and (iv) all current directors and
executive officers as a group. Except as otherwise indicated, the Company
believes that the beneficial owners of the Common Stock listed below, and the
information furnished by such owners, have sole investment and voting power with
respect to such shares, subject to community property laws where applicable.
 
   
<TABLE>
<CAPTION>
                                                              NUMBER OF
                            NAME                              SHARES(1)    PERCENTAGE
                            ----                              ---------    ----------
<S>                                                           <C>          <C>
Sprout Capital VII, L.P.(2).................................  2,768,671       20.5%
  3000 Sand Hill Road
  Building 3 Suite 170
  Menlo Park, CA 94025
Domain Partners III, L.P.(3)................................  1,266,859        9.4
  One Palmer Square, Suite 515
  Princeton, NJ 08542
Amerindo Investment Advisors Inc.(4)........................  1,220,000        9.0
  One Embarcadero Center, Suite 2300
  San Francisco, CA 94111
Sierra Ventures IV, L.P.(5).................................    825,820        6.1
  3000 Sand Hill Road
  Building Four, Suite 210
  Menlo Park, CA 94025
New York Life Insurance Company(6)..........................    715,432        5.3
  51 Madison Ave
  New York, NY 10010
State of Wisconsin Investment Board(4)......................    695,000        5.1
  P.O. Box 7842
  Madison, WI 53707
SmithKline Beecham Properties, Ltd.(7)......................    637,733        7.0
  1403 Foulk Road #102
  Wilmington, DE 19803-2775
Thomas G. Wiggans(8)........................................    248,998        1.8
Alexander E. Barkas, Ph.D.(9)...............................    167,978        1.2
Eugene A. Bauer, M.D........................................    145,467        1.1
Brian H. Dovey(3)(10).......................................  1,277,398        9.4
G. Kirk Raab(11)............................................    101,422       *
Thomas D. Kiley(12).........................................     88,732       *
W. Scott Harkonen(13).......................................     64,803       *
Ernst H. Rinderknecht, Ph.D.(14)............................     58,075       *
Cynthia M. Butitta(15)......................................     50,039       *
David A. Lowin, Esq.(16)....................................     48,507       *
Richard J. Hammel(17).......................................     47,871       *
Kenneth B. Plumlee(18)......................................     30,500       *
Joseph J. Ruvane, Jr.(19)...................................     29,496       *
John L. Higgins, Vice President and Chief Financial
  Officer(20)...............................................     19,042       *
John C. Kane(21)............................................     12,500       *
All directors and officers as a group (14
  persons)(8)-(20)..........................................  2,340,789       17.7%
</TABLE>
    
 
- ---------------
  *  Less than 1%.
 
 (1) Beneficial ownership is determined in accordance with the rules of the
     Securities and Exchange Commission. The number of shares beneficially owned
     by a person includes shares of Common Stock
 
                                       27
<PAGE>   31
 
     subject to options or warrants held by that person that are currently
     exercisable or exercisable within 60 days of February 27, 1998. Such
     exercisable options or warrants are shown in the footnotes to this table
     for each such person. Such shares, however, are not deemed outstanding for
     the purposes of computing the percentage ownership of each other person.
 
 (2) Includes 1,146,200 shares held by Sprout Capital VII, L.P., 267,119 shares
     held by Sprout Capital VI, L.P., 68,823 shares held by DLJ Capital
     Corporation, 7,412 shares held by The Sprout CEO Fund L.P., 521,618 shares
     held by Sprout Growth II, L.P., 132,621 shares held by DLJ First ESC LLC,
     243,790 shares held by Sprout Growth II, 301,335 shares issuable upon
     exercise of warrants held by Sprout Capital VII, L.P., exercisable within
     60 days of February 27, 1998, 1,648 shares issuable upon exercise of
     warrants held by Sprout Capital VI, L.P., exercisable within 60 days of
     February 27, 1998, 12,657 shares issuable upon exercise of warrants held by
     DLJ Capital Corporation, exercisable within 60 days of February 27, 1998,
     3,464 shares issuable upon exercise of warrants held by The Sprout CEO Fund
     L.P., exercisable within 60 days of February 27, 1998 and 61,984 shares
     issuable upon exercise of warrants held by DLJ First ESC LLC, exercisable
     within 60 days of February 27, 1998.
 
 (3) Includes 1,156,301 shares held by Domain Partners III, L.P., 40,236 shares
     held by DP III Associates, L.P., 4,215 shares held by Domain Associates,
     63,898 shares issuable upon exercise of warrants held by Domain Partners
     III, L.P., exercisable within 60 days of February 27, 1998 and 2,209 shares
     issuable upon exercise of warrants held by DP III Associates L.P.,
     exercisable within 60 days of February 27, 1998. Brian H. Dovey, a general
     partner of the general partner of Domain Partners III, L.P. and DP III
     Associates, L.P., is a director of the Company. Mr. Dovey is also a general
     partner of Domain Associates. Mr. Dovey disclaims beneficial ownership of
     such shares except to the extent of his pecuniary interest in such shares.
 
 (4) All of such shares are owned by clients of Amerindo Investment Advisors
     Inc. ("Amerindo"), an investment advisory firm. Alberto W. Vilar and Gary
     A. Tanaka are the sole shareholders and directors of Amerindo, and together
     with Amerindo, have shared voting and dispositive powers with respect to
     such shares. Amerindo, Mr. Vilar, and Mr. Tanaka have all disclaimed
     beneficial ownership over the shares. Such information has been obtained
     from a filing on Form 13-G by Amerindo, Mr. Vilar and Mr. Tanaka.
 
   
 (5) Includes 789,382 shares held by Sierra Ventures IV, L.P., 31,605 shares
     held by Sierra Ventures IV International, L.P., 4,647 shares issuable upon
     exercise of warrants held by Sierra Ventures IV, L.P., exercisable within
     60 days of February 27, 1998 and 186 shares issuable upon exercise of
     warrants held by Sierra Ventures IV International, L.P., exercisable within
     60 days of February 27, 1998.
    
 
 (6) Includes 124,651 shares issuable upon exercise of outstanding warrants
     exercisable within 60 days of February 27, 1998.
 
 (7) The Company may be obligated to issue additional shares to SmithKline
     Beecham Properties, Ltd. on April 1, 1998 to bring the total value of the
     shares owned by such stockholder to $8.0 million. See "Certain
     Relationships and Related Transactions."
 
 (8) Includes 48,357 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
 (9) Includes 14,754 shares issuable upon exercise of outstanding options
     exercisable within 60 days of February 27, 1998, 11,855 shares issuable
     upon exercise of warrants held by Alexander E. Barkas and Lynda L. Wijcik,
     exercisable within 60 days for February 27, 1998. Also includes 17,985
     shares of Common Stock owned by Lynda L. Wijcik, spouse of Dr. Barkas.
 
(10) Includes 10,539 shares issuable upon exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(11) Includes 95,802 shares issuable upon exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(12) Includes 62,482 shares held in the Thomas D. and Nancy L.M. Kiley Revocable
     Trust under Agreement dated August 7, 1981. Also includes 26,250 shares
     issuable upon exercise of outstanding options exercisable within 60 days of
     February 27, 1998.
 
                                       28
<PAGE>   32
 
(13) Includes 61,678 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(14) Includes 21,628 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(15) Includes 29,255 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(16) Includes 25,297 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(17) Includes 46,439 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(18) Includes 7,500 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(19) Represents 29,496 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
(20) Includes 250 shares of Common Stock held by Amy K. Higgins, spouse of Mr.
     Higgins. Also includes 16,042 shares issuable upon the exercise of
     outstanding options exercisable within 60 days of February 27, 1998.
 
(21) Includes 7,500 shares issuable upon the exercise of outstanding options
     exercisable within 60 days of February 27, 1998.
 
                                 OTHER BUSINESS
 
     The Board of Directors is not aware of any other matter which may be
presented for action at the Annual Meeting other than the matters set forth in
this Proxy Statement. Should any other matter requiring a vote of the
stockholders arise, it is intended that the persons named as proxy holders on
the enclosed proxy card will vote the shares represented thereby in accordance
with their best judgment in the interest of the Company. Discretionary authority
with respect to such other matters is granted by the execution of the enclosed
proxy.
 
                             STOCKHOLDER PROPOSALS
 
     Under the present rules of the Commission, the deadline for stockholders to
submit proposals to be considered for inclusion in the Company's Proxy Statement
and form of proxy for the next year's Annual Meeting of Stockholders is expected
to be December 2, 1998. Such proposals may be included in next year's Proxy
Statement and form of proxy if they comply with certain rules and regulations
promulgated by the Commission.
 
                           INCORPORATION BY REFERENCE
 
     According to the provisions of Schedule 14A under the Securities Exchange
Act of 1934, the following document or portion thereof is incorporated by
reference:
 
     "Executive Officers of the Company" from Part I of the Company's Annual
Report on Form 10-K for the year ended December 31, 1997.
 
                                       29
<PAGE>   33
 
                        ADDITIONAL INFORMATION AVAILABLE
 
     THE COMPANY WILL PROVIDE WITHOUT CHARGE, UPON WRITTEN REQUEST, A COPY OF
THE COMPANY'S ANNUAL REPORT ON FORM 10-K, INCLUDING FINANCIAL STATEMENTS,
SCHEDULES AND A LIST OF EXHIBITS. REQUEST SHOULD BE SENT TO THE ATTENTION OF
JOHN L. HIGGINS, VICE PRESIDENT, FINANCE AND ADMINISTRATION, AND CHIEF FINANCIAL
OFFICER AT CONNETICS CORPORATION, 3400 WEST BAYSHORE ROAD, PALO ALTO, CALIFORNIA
94303, OR TELEPHONED TO 650-843-2800.
 
                                          By Order of the Board of Directors,
 
                                          Joshua L. Green,
                                          Secretary
Dated: March 31, 1998
 
                                       30
<PAGE>   34
 
PROXY                         CONNETICS CORPORATION                        PROXY
                  ANNUAL MEETING OF STOCKHOLDERS, MAY 22, 1998
    THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS OF CONNETICS
                                  CORPORATION
 
    The undersigned revokes all previous proxies, acknowledges receipt of the
Notice of the Annual Meeting of Stockholders to be held on May 22, 1998 and the
Proxy Statement and appoints Thomas G. Wiggans and John L. Higgins, and each of
them, as the Proxy of the undersigned, with full power of substitution, to vote
all shares of Common Stock of Connetics Corporation (the "Company") which the
undersigned is entitled to vote, either on his or her own behalf or on behalf of
any entity or entities, at the Annual Meeting of Stockholders of the Company to
be held at the Company's facilities located at 3400 West Bayshore Road, Palo
Alto, California 94303, on Friday, May 22, 1998 at 9:00 a.m. (the "Annual
Meeting"), and at any adjournment or postponement thereof, with the same force
and effect as the undersigned might or could do if personally present thereat.
The shares represented by this Proxy shall be voted in the following manner:
[X] Please mark your choices like this
 
1.  To elect the following directors to serve until the next annual meeting of
    stockholders or until their successors are elected and qualified:
 
                 [ ] FOR          [ ] WITHHOLD AUTHORITY TO VOTE
NOMINEES:
 
    G. Kirk Raab; Thomas G. Wiggans; Eugene A. Bauer, M.D.; Alexander E. Barkas,
    Ph.D.; Brian H. Dovey; John C. Kane; Thomas D. Kiley; Kenneth B. Plumlec;
    Joseph J. Ruvane, Jr.
 
2.  To approve an amendment to the 1994 Stock Plan to increase the number of
    shares of Common Stock reserved for issuance thereunder by 600,000 shares to
    an aggregate of 2,600,000 shares;    [ ] FOR          [ ] AGAINST          [
    ] ABSTAIN
 
3.  To approve an amendment to the 1995 Directors' Stock Plan to increase the
    number of shares of Common Stock reserved for issuance thereunder by 100,000
    shares to an aggregate of 250,000 shares;                 [ ] FOR          [
    ] AGAINST          [ ] ABSTAIN
 
4.  To approve an amendment to the 1995 Employee Stock Purchase Plan to increase
    the number of shares of Common Stock reserved for issuance thereunder by
    400,000 shares to an aggregate of 500,000 shares          [ ] FOR          [
    ] AGAINST          [ ] ABSTAIN
 
                                                                See reverse side
<PAGE>   35
 
5.  To ratify the Board of Director's selection of Ernst & Young LLP to serve as
    the Company's independent auditors for the fiscal year ending December 31,
    1998; and                  [ ] FOR          [ ] AGAINST          [ ] ABSTAIN
 
6.  To transact such other business as may properly come before the Annual
    Meeting or any adjournment or postponement thereof.       [ ] FOR          [
    ] AGAINST          [ ] ABSTAIN
 
    The Board of Directors recommends a vote FOR each of the directors listed
above and a vote FOR the other proposals. This Proxy, when properly executed,
will be voted as specified above. THIS PROXY WILL BE VOTED FOR THE ELECTION OF
THE DIRECTORS LISTED ABOVE AND FOR THE OTHER PROPOSALS IF NO SPECIFICATION IS
MADE.
 
                                                     Date:
 
                                                     ---------------------------
                                                     (Please print the name(s)
                                                     appearing on each share
                                                     certificate(s) over which
                                                     you have voting authority.)
 
                                                     ---------------------------
                                                     Please sign your name:
                                                     (Authorized Signature(s))
 
                                                     ---------------------------
                                                             Please sign
 
                                                     ---------------------------
                                                             Please sign


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