PHYSICIANS INFORMATION EXCHANGE INC
424B3, 1996-10-07
COMPUTER INTEGRATED SYSTEMS DESIGN
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                                                 Filing pursuant to Rule 424(c)
                                                 and 424(b)(3) of the Securities
                                                        Act of 1933, as amended.
                                              Registration Statement on Form S-1
                                                                  (No. 333-3618)


                    15,000,000 Shares of Class A Common Stock
                       1,885 Units of Class B Common Stock
          (each Unit representing 9,550 Shares of Class B Common Stock)

                      PHYSICIANS INFORMATION EXCHANGE, INC.


FIRST SUPPLEMENT DATED OCTOBER 7, 1996
TO PROSPECTUS DATED JULY 16, 1996


                 Terms used in this Supplement and not otherwise
                  defined are used as defined in the Prospectus

     On September 24, 1996, the Company  entered into a strategic  alliance with
ATAC CPA Healthcare Network ("ATAC"), a Texas non-profit corporation.  ATAC is a
nationwide  consortium  of certified  public  accountant  firms that provides to
physicians  healthcare cost  accounting,  clinic  re-engineering  and healthcare
consulting.  ATAC will market  PIE's  products  and  services to  physicians  in
conjunction  with ATAC's own  services.  PIE has agreed to  provide,  at its own
expense, CRIS to physicians using ATAC services;  provided, that such physicians
agree to provide  clinical  data to PIE in exchange  for CRIS.  PIE will receive
one-third of all revenues  received by ATAC pursuant to the alliance;  provided,
however,  that revenues received from a physician will be held by ATAC in escrow
for the benefit of PIE until PIE has made CRIS available to the specialty  group
of such physician.  Depending upon the success of this alliance, the Company may
determine  to  suspend  the sale of  Common  Stock,  pursuant  to its  effective
registration statement.

     On August 10, 1996,  the Board of Directors  elected  Clarke  Williams as a
director of the Company. Since 1968, Mr. Williams has been Chairman of the Board
of Century Telephone Enterprises,  Inc. ("CTE"). From 1968 to 1992, Mr. Williams
also served as either President or Chief Executive Officer of CTE.

     On August 19,  1996,  the Board of  Directors  agreed to accept  promissory
notes under certain circumstances in consideration for the sale of Common Stock.




CORPDAL:55741.1  29375-00002

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