<PAGE> 1
SCHEDULE 14A
(RULE 14a-101)
INFORMATION REQUIRED IN PROXY STATEMENT
SCHEDULE 14A INFORMATION
PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES
EXCHANGE ACT OF 1934 (AMENDMENT NO. )
Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[ ] Preliminary Proxy Statement [ ] Confidential, for Use by the
Commission Only (as permitted by
Rule 14a-6(e)(2))
[X] Definitive Proxy Statement
[ ] Definitive Additional Materials
[ ] Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12
ARQULE, INC.
----------------------------------------------------------------
(Name of Registrant as Specified in Its Charter)
----------------------------------------------------------------
(Name of Person(s) Filing Proxy Statement,
if other than the Registrant)
Payment of Filing Fee (Check the appropriate box):
[X] No fee required.
[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.
(1) Title of each class of securities to which transaction applies:
(2) Aggregate number of securities to which transaction applies:
(3) Per unit price or other underlying value of transaction
computed pursuant to Exchange Act Rule 0-11 (Set forth the
amount on which the filing fee is calculated and state how it
was determined):
(4) Proposed maximum aggregate value of transaction:
(5) Total fee paid:
[ ] Fee paid previously with preliminary materials.
[ ] Check box if any part of the fee is offset as provided by Exchange
Act Rule 0-11(a)(2) and identify the filing for which the offsetting
fee was paid previously. Identify the previous filing by registration
statement number, or the form or schedule and the date of its filing.
(1) Amount Previously Paid:
(2) Form, Schedule or Registration Statement No.:
(3) Filing Party:
(4) Date Filed:
<PAGE> 2
Dear ArQule Shareholder,
We are pleased to report that during the past year, ArQule has successfully
established a world leadership position in the development and application of
high-throughput chemistry technologies for accelerating the discovery and
development of compounds for multiple markets.
By any measure, ArQule is now the leading dedicated chemistry company in drug
discovery, having partnered with seven world-class pharmaceutical and
agrochemical companies to generate and optimize compounds. To date, we have also
signed a total of 18 biotechnology company partnerships, while retaining shared
ownership of resulting clinical candidates.
To support our efforts, ArQule has built one of the most sophisticated centers
of chemistry technology and discovery in the world. We have amassed an in-house
team of 51 Ph.D. scientists and 12 technical professionals with advanced
degrees. We have a Scientific Advisory Board comprised of 13 academic
scientists, representing structural biology, synthetic organic chemistry,
mechanistic biology, structure guided design, analytical chemistry, engineering,
theoretical chemistry and catalysis. These individuals open the door to the
newest and most innovative chemistry technologies, giving ArQule a "first view"
of the future.
In order to attract and retain employees of the highest caliber, ArQule offers
its employees competitive compensation packages that provide stock option-based
incentives. Our belief is that by granting options, we can give everyone at
ArQule a direct economic stake in our shareholders' success. To this end, we are
requesting your approval for an increase to the number of shares available for
option grants of 1.5 million shares. We firmly believe that there is enormous
value to be realized from the application of our chemistry based technologies in
the life sciences and other markets. As a result, we are taking this important
step to attract the necessary talent and motivate everyone at ArQule to continue
to create value for all our shareholders.
If you have any questions about this issue, or any of the issues outlined in the
proxy, please don't hesitate to call. In the meantime, we will keep you informed
of our continued progress.
Sincerely,
/s/ Eric B. Gordon
Eric B. Gordon
President and CEO
<PAGE> 3
ARQULE, INC.
NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
The 1998 Annual Meeting of Stockholders of ArQule, Inc., a Delaware
corporation (the "Company"), will be held at The DoubleTree Guest Suites Hotel,
400 Soldiers Field Road, Boston, Massachusetts 02134 at 8:30 a.m. on Thursday,
May 14, 1998 for the following purposes:
1. To elect two directors to hold office for a term of three
years and until their respective successors are elected and
qualified.
2. To approve an amendment to the Company's Amended and Restated
1994 Equity Incentive Plan to increase the aggregate number of
shares of the Company's common stock as to which awards may be
granted under such plan by 1,500,000 shares.
3. To transact such other business as may be in furtherance of or
incidental to the foregoing or as may otherwise properly come
before the meeting.
Only stockholders of record at the close of business on April 2, 1998
will be entitled to vote at the meeting or any adjournment thereof. A list of
such stockholders will be open for examination by any stockholder for any
purpose germane to the meeting for ten days before the meeting during ordinary
business hours at the offices of Palmer & Dodge LLP, One Beacon Street, Boston,
Massachusetts 02108.
IT IS IMPORTANT THAT YOUR SHARES BE REPRESENTED AT THE MEETING.
THEREFORE, WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE COMPLETE YOUR
PROXY AND RETURN IT IN THE ENCLOSED ENVELOPE, WHICH REQUIRES NO POSTAGE IF
MAILED IN THE UNITED STATES. IF YOU ATTEND THE MEETING AND WISH TO VOTE IN
PERSON, YOUR PROXY WILL NOT BE USED.
By order of the Board of Directors,
MICHAEL LYTTON, Secretary
Dated: April 15, 1998
<PAGE> 4
ARQULE, INC.
200 Boston Avenue
Medford, Massachusetts 02155
Telephone: (781) 395-4100
---------------
Proxy Statement
---------------
The enclosed proxy is solicited on behalf of the Board of Directors of
ArQule, Inc. (the "Company") for use at the 1998 Annual Meeting of Stockholders
to be held on Thursday, May 14, 1998, and at any adjournments thereof. The
approximate date on which this proxy statement and accompanying proxy are first
being sent or given to security holders is April 15, 1998.
The principal business expected to be transacted at the meeting, as
more fully described below, will be the election of two directors and an
amendment to the Company's Amended and Restated 1994 Equity Incentive Plan (the
"Equity Plan").
The authority granted by an executed proxy may be revoked at any time
before its exercise by filing with the Secretary of the Company a written
revocation or a duly executed proxy bearing a later date or by voting in person
at the meeting.
The Company will bear the cost of the solicitation of proxies,
including the charges and expenses of brokerage firms and others for forwarding
solicitation material to beneficial owners of stock. In addition to the use of
mails, proxies may be solicited by officers and employees of the Company in
person or by telephone.
VOTING SECURITIES AND VOTES REQUIRED
Only stockholders of record at the close of business on April 2, 1998
will be entitled to vote at the meeting. On that date, the Company had
outstanding 11,942,882 shares of Common Stock, $0.01 par value (the "Common
Stock"), each of which is entitled to one vote. A majority in interest of the
outstanding Common Stock, represented at the meeting in person or by proxy,
constitutes a quorum for the transaction of business. A plurality of the votes
cast is required to elect the nominees for director. A majority of the votes
cast is required to approve the proposed amendment to the Equity Plan. Broker
non-votes will not be counted in determining the shares entitled to vote nor
treated as votes cast. A "broker non-vote" occurs when a registered broker
holding a customer's shares in the name of the broker has not received voting
instructions on the matter from the customer, is barred by applicable rules from
exercising discretionary voting authority in the matter, and so indicates on the
proxy. Abstentions will not be treated as votes cast in the election of
directors or the amendment to the Equity Plan.
- 1 -
<PAGE> 5
ELECTION OF DIRECTORS
The number of directors is fixed at seven for the coming year and is
divided into three classes. At the meeting, two directors will be elected to
hold office for three years and until their successors are elected and
qualified. Allan R. Ferguson and Joseph C. Hogan, Jr., Ph.D., who are presently
serving as directors, have been nominated for re-election by the Board of
Directors. Unless the enclosed proxy withholds authority to vote for one or more
of the nominees or is a broker non-vote, the shares represented by such proxy
will be voted for the election of the directors as the Board's nominees. If
either nominee is unable to serve, which is not expected, the shares represented
by the enclosed proxy will be voted for such other candidate as may be nominated
by the Board of Directors.
The following table contains certain information about the nominees for
director and each other person whose term of office as a director will continue
after the meeting.
<TABLE>
<CAPTION>
PRESENT
DIRECTOR TERM
NAME AND AGE BUSINESS EXPERIENCE AND OTHER DIRECTORSHIPS SINCE EXPIRES
------------ ------------------------------------------- -------- -------
<S> <C> <C> <C>
Stephen M. Dow Stephen M. Dow has been a director of the Company 1993 2000
Age: 42 since its inception in December 1993. Since 1983, he
has been a general partner of Sevin Rosen Funds, a
venture capital investment firm. Mr. Dow serves as a
director of Citrix Systems, Inc., Corsair
Communications, Inc. and several privately held
companies.
Allan R. Ferguson* Allan R. Ferguson has been a director of the 1993 1998
Age: 55 Company since its inception in December 1993. He has
been a general partner of Atlas Venture since 1993
and managing partner of Aspen Ventures since 1991,
both venture capital firms. From 1986 through 1991,
Mr. Ferguson was the President of 3i Ventures, a
venture capital firm. Prior to his venture capital
experience, Mr. Ferguson held senior level
positions in operations at Johnson & Johnson and
Damon Biotech. Mr. Ferguson serves as a director of
AutoImmune Inc. and several privately held
companies.
L. Patrick Gage, L. Patrick Gage, Ph.D. has been a director of the 1998 1999
Ph.D. Company since January 1998. Since March 1998, Dr.
Age: 55 Gage has been the President of Wyeth-Ayerst
Pharmaceuticals, a division of American Home
Products Corporation, a pharmaceutical company.
Prior to that, Dr. Gage had been employed by
Genetics Institute, Inc., a biopharmaceutical
company since 1989 in a variety of positions, most
recently as President.
</TABLE>
- 2 -
<PAGE> 6
<TABLE>
<CAPTION>
PRESENT
DIRECTOR TERM
NAME AND AGE BUSINESS EXPERIENCE AND OTHER DIRECTORSHIPS SINCE EXPIRES
------------ ------------------------------------------- -------- -------
<S> <C> <C> <C>
Eric B. Gordon Eric B. Gordon has been the President, Chief 1996 2000
Age: 50 Executive Officer and a director of the Company
since January 1996. From 1987 until he joined the
Company, Mr. Gordon served in various capacities in
the United States and Europe with Pasteur Merieux
Connaught, a pharmaceutical company, most recently
as Vice President and Chief Financial Officer. In
addition, since 1 93 he held the additional
position of Chief Executive Officer of Virogenetics
Corporation, a partially owned joint venture
company and since 1994 Corporate Vice President and
Treasurer of Pasteur Merieux.
Joseph C. Hogan, Joseph C. Hogan, Jr., Ph.D. is a founder of the 1993 1998
Jr., Ph.D.* Com any and has served as the Chief Scientific Officer
Age: 56 and Senior Vice President of Research and Development
since its inception in December 1993. Dr. Hogan has
served as the Chairman of the Board since January
1996. From 1990 until he founded the Company, Dr.
Hogan was the founder and president of Applied
Modular Chemistries, Inc., a chemistry company.
Adrian de Jonge, Adrian de Jonge, Ph.D. has been a director of the 1995 1999
Ph.D. Company since November 1995. Since October 1997,
Age: 42 Dr. de Jonge has been a member of the Executive Board
of Campina Melkunie B.V., a dairy products company.
From 1987 until October 1997, Dr. de Jonge was
employed by Solvay Duphar B.V., a pharmaceutical
company, in a variety of positions, most recently
as the Vice President of Research of Solvay Duphar
B.V.'s Pharmaceuticals Division.
</TABLE>
- 3 -
<PAGE> 7
<TABLE>
<CAPTION>
PRESENT
DIRECTOR TERM
NAME AND AGE BUSINESS EXPERIENCE AND OTHER DIRECTORSHIPS SINCE EXPIRES
------------ ------------------------------------------- -------- -------
<S> <C> <C> <C>
Michael Rosenblatt, Michael Rosenblatt, M.D. has been a director of the 1998 1999
M.D. Company since April 9, 1998. Since 1992, Dr.
Age: 50 Rosenblatt has been the Robert H. Ebert Professor of
Molecular Medicine at the Harvard Medical School,
Chief of the Division of Bone and Mineral
Metabolism at Beth Israel Hospital, and the
director of the Harvard-MIT Division of Health
Sciences and Technology. Since 1993, he has also
been a faculty member in the department of
Biological Chemistry and Molecular Pharmacology,
Biological and Biomedical Sciences Program of the
Division of Medical Sciences at Harvard University.
Since 1996, he has been the executive director of
the Harvard/Beth Israel Deaconess Mount Auburn
Institute for Education and Research and a Harvard
faculty dean for academic programs at the Beth
Israel Deaconess Medical Center. Prior to 1992, Dr.
Rosenblatt was the Senior Vice President for
Research at Merck Sharp & Dohme Research
Laboratories, a pharmaceutical company. Dr.
Rosenblatt serves as a director of Creative
Biomolecules, Inc.
</TABLE>
* Nominee for election as director
COMMITTEES OF THE BOARD
The Audit Committee, which in 1997 consisted of Messrs. Ferguson and de
Jonge, is responsible for providing the Board of Directors with an independent
review of the financial health of the Company and its financial controls and
reporting. Its primary functions are to recommend independent auditors to the
Board of Directors, review the results of the annual audit and the auditors'
reports, and ensure the adequacy of the Company's financial controls and
procedures. The Audit Committee met six times in 1997. The Compensation
Committee, which in 1997 consisted of Messrs. Ferguson and Dow, acts for the
Board of Directors with respect to the Company's compensation practices and
their implementation. It sets and implements the compensation of the Company's
officers and administers the Equity Plan and the 1996 Employee Stock Purchase
Plan. The Compensation Committee held ten meetings in 1997. Since his election
to the Board of Directors in January 1998, Dr. Gage has served on the
Compensation Committee. The entire Board of Directors functions as a nominating
committee, considering nominations submitted to the Chairman of the Board. The
Board of Directors held eight meetings during 1997, and each director attended
at least 75% of all meetings of the Board and of all committees of the Board on
which he served, except Dr. de Jonge, who attended 62.5% of the aggregate of
such meetings.
- 4 -
<PAGE> 8
DIRECTOR COMPENSATION
The directors of the Company do not receive additional compensation for
their services as directors. However, all directors who are not employees of the
Company are currently eligible to participate in the Amended and Restated 1996
Director Stock Option Plan (the "Director Plan").
The Director Plan provides that each director who is not an employee of
the Company and is serving as a director prior to and immediately after any
annual meeting of stockholders (whether or not a director is being re-elected)
receives an automatic grant of an option to purchase 3,500 shares of Common
Stock. This option is fully exercisable on the date of grant. In addition, upon
the initial election of a director, that is not an employee of the Company, such
director receives an automatic grant of an option to purchase 7,500 shares of
Common Stock. This option becomes exercisable with respect to 2,500 shares on
the date of the Company's next annual meeting of stockholder from the date of
grant and each of the next two annual meetings of stockholders following such
annual meeting, so long as the director remains in office. The options have a
term of ten years and an exercise price equal to the closing price of the Common
Stock as reported by the Nasdaq National Market on the last trading day prior to
the date of grant. The Director Plan authorizes the grant of stock options to
purchase up to a maximum of 125,000 shares of Common Stock (subject to
adjustments for stock splits and similar capital changes).
Messrs. Ferguson, Dow, and de Jonge each received grants of options to
purchase 3,500 shares in May 1997. Drs. Gage and Rosenblatt each received an
option to purchase 7,500 shares on his election to the Board in January and
April 1998, respectively.
- 5 -
<PAGE> 9
STOCK PERFORMANCE GRAPH
The following graph shows the cumulative total stockholder return on
the Company's Common Stock over the period from October 16, 1996 (the first
trading day of the Company's Common Stock) to December 31, 1997, as compared
with that of the Nasdaq Stock Market Index and the Nasdaq Pharmaceuticals Index,
based on an initial investment of $100 in each on October 16, 1996. Total
stockholder return is measured by dividing share price change plus dividends, if
any, for each period by the share price at the beginning of the respective
period, and assumes reinvestment of dividends.
COMPARISON OF CUMULATIVE TOTAL RETURN OF
ARQULE, INC., NASDAQ STOCK MARKET (U.S. COMPANIES) INDEX AND
AND NASDAQ PHARMACEUTICALS INDEX
[GRAPH OMITTED]
<TABLE>
<CAPTION>
Nasdaq Stock
Market (U.S. Nasdaq
Measurement Period Companies) Pharmaceuticals
(Fiscal Year Covered) ArQule, Inc. Index Index
<S> <C> <C> <C>
10/16/96 100 100 100
12/31/96 118.868 102.905 100.244
12/31/97 173.117 126.316 103.535
</TABLE>
- 6 -
<PAGE> 10
COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION
The Compensation Committee Report set forth below describes the
compensation policies applicable to executive officers of the Company, including
Mr. Gordon, the Company's Chief Executive Officer.
Overall Policy. The Company's executive compensation program is
designed to be closely linked to corporate performance and returns to
stockholders. To this end, the Company has developed an overall compensation
strategy and specific compensation plan that tie a portion of executive
compensation to the Company's success in meeting specified performance goals. In
addition, through the use of stock options, the Company ensures that a part of
the executives' compensation is closely tied to appreciation in the Company's
stock price. The overall objectives of this strategy are to attract and retain
the best possible executive talent, to motivate these executives to achieve the
goals inherent in the Company's business strategy, to link executive and
stockholder interests through equity based plans and, finally, to provide a
compensation package that recognizes individual contributions as well as overall
business results.
The Compensation Committee determines the compensation of all corporate
officers, including the three most highly compensated corporate executives named
in the Summary Compensation Table. The Compensation Committee takes into account
the views of Mr. Gordon, the Company's Chief Executive Officer and reviews a
number of compensation surveys to insure the competitiveness of the compensation
offered by the Company for the purposes of recruiting and retaining key
management.
The key elements of the Company's executive compensation consist of
base salary and stock options. The Compensation Committee's policies with
respect to each of these elements, including the bases for the compensation
awarded to Mr. Gordon, are discussed below. In addition, while the elements of
compensation described below are considered separately, the Compensation
Committee takes into account the full compensation package afforded by the
Company to the individual, including insurance and other employee benefits.
Base Salaries. Base salaries for new executive officers are initially
determined by evaluating the responsibilities of the position held and the
experience of the individual. In making determinations regarding base salaries,
the Compensation Committee considers generally available information regarding
salaries prevailing in the industry, but does not utilize any particular indices
or peer groups.
Annual salary adjustments are determined by evaluating the financial
performance of the Company and of particular aspects of the business under the
control of the particular executive officer. The Compensation Committee, where
appropriate, also considers non-financial performance measures. These
non-financial performance measures may include such factors as efficiency gains,
new responsibilities assumed by the executive, quality improvements and
improvements in relations with collaborators and employees. No particular weight
is given to any of these non-financial factors.
The base salary for 1997 for each of the executive officers, including
Mr. Gordon, was based on the performance of the individual as well as a review
of compensation paid to persons holding comparable positions in other
biotechnology companies. Mr. Gordon was paid a base salary of $246,694 for 1997,
an increase of 12% over his paid $219,808 base salary for 1996.
Stock Options. Under the Company's Equity Plan, stock options are
granted to the Company's executive officers. Stock options are designed to align
the interests of executives with those of the stockholders. Stock options are
granted with an exercise price equal to the fair market value of the Common
Stock on the date of grant and vest over various periods of time, normally four
years or upon
- 7 -
<PAGE> 11
the achievement of specified milestones. Stock option grants are designed to
encourage the creation of stockholder value over the long term since the full
benefit of the compensation package cannot be realized unless stock price
appreciation is achieved, and, once achieved, is maintained and improved upon.
In determining the amount of such grants, the Compensation Committee evaluates
the job level of the executive, responsibilities to be assumed in the upcoming
year, and responsibilities in prior years, and also takes into account the size
of the officer's awards in the past.
Conclusion. As described above, a very significant portion of the
Company's executive compensation is linked directly to individual and corporate
performance and stock appreciation. The Compensation Committee intends to
continue the policy of linking executive compensation to Company performance and
returns to stockholders, recognizing that the ups and downs of the business
cycle from time to time may result in an imbalance for a particular period.
By the Compensation Committee,
Stephen M. Dow
Allan R. Ferguson
- 8 -
<PAGE> 12
EXECUTIVE COMPENSATION
SUMMARY COMPENSATION TABLE
The following table provides summary information on the cash
compensation and certain other compensation paid, awarded, or accrued by the
Company and its subsidiaries to or for the Chief Executive Officer of the
Company and each of the Company's other executive officers whose total salary
and bonus exceeded $100,000 during the fiscal year ended December 31, 1997
(collectively, the "Named Executive Officers").
<TABLE>
<CAPTION>
ANNUAL COMPENSATION LONG-TERM
----------------------------------------------- COMPENSATION
AWARDS
------------
OTHER ANNUAL SECURITIES
COMPENSATION UNDERLYING ALL OTHER
NAME AND PRINCIPAL POSITION YEAR SALARY($) BONUS ($) OPTIONS(#) COMPENSATION($)
- --------------------------- ---- --------- ----- ------------ ------------ ---------------
<S> <C> <C> <C> <C> <C> <C>
Eric B. Gordon (1) .................... 1997 $246,694 -- -- $88,336(2)
President and Chief Executive 1996 219,808 -- $143,113(3) 464,920 --
Officer 1995 -- -- -- -- --
Joseph C. Hogan, Jr., Ph.D ............ 1997 203,892 35,200 30,000(4)
Chairman of the Board, Senior 1996 171,308 -- 435(5) -- 30,000(4)
Vice President of Research and 1995 150,000 -- -- -- --
Development and Chief Scientific
Officer
James R. Fitzgerald, Jr.(6) ........... 1997 154,376 11,880
Vice President, Chief Financial 1996 51,346 -- -- 50,000 --
Officer and Treasurer 1995 -- -- -- --
</TABLE>
- ---------------------
(1) Mr. Gordon commenced employment with the Company in January 1996. Terms
of his employment are described under "Executive Employment
Agreements."
(2) Consists of amount of indebtedness owed by Mr. Gordon on February 15,
1998 to the Company that was forgiven by the Company upon the
achievement of certain milestones by Mr. Gordon in the fiscal year
ended December 31, 1997.
(3) Consists of reimbursement of relocation expenses incurred by Mr. Gordon
during the fiscal year ended December 31, 1996 in connection with
his becoming an employee of the Company.
(4) Consists of amount of indebtedness owed by Dr. Hogan to the Company
that was forgiven by the Company during the fiscal year ended December
31, 1996 and December 31, 1997, respectively.
(5) Consists of Medicare taxes owed by Dr. Hogan that were paid by the
Company.
(6) Mr. Fitzgerald commenced employment with the Company in July 1996.
Terms of his employment are described under "Executive Employment
Agreements."
- 9 -
<PAGE> 13
STOCK OPTION GRANTS IN LAST FISCAL YEAR
The following table sets forth certain information regarding options
granted during the fiscal year ended December 31, 1997 by the Company to the
Named Executive Officers:
<TABLE>
<CAPTION>
POTENTIAL REALIZABLE
VALUE OF ASSUMED
NUMBER OF PERCENT OF ANNUAL RATES OF STOCK
SECURITIES TOTAL OPTIONS PRICE APPRECIATION FOR
UNDERLYING GRANTED EXERCISE OR OPTION TERM(1)
OPTIONS EMPLOYEES IN BASE PRICE EXPIRATION ----------------------
GRANTED(#) FISCAL YEAR ($/SHARE)(2) DATE 5%($) 10%($)
---------- ------------- ------------ ---------- --------- ---------
<S> <C> <C> <C> <C> <C> <C>
Eric B. Gordon................... -- -- -- -- -- --
Joseph C. Hogan, Jr., Ph.D....... 35,200(3) 3.76% $14.125 4/3/07 $312,686 $675,136
James R. Fitzgerald, Jr.......... 11,880(3) 1.27% $14.125 4/3/07 $105,530 $227,858
</TABLE>
- ---------------------
(1) The dollar amounts under these columns are the result of calculations
at the 5% and 10% rates set by the Securities and Exchange Commission
and, therefore, are not intended to forecast possible future
appreciation, if any, in the price of the underlying Common Stock. No
gain to the optionees is possible without an increase in price of the
underlying Common Stock, which will benefit all stockholders
proportionately.
(2) The exercise price of these options is equal to the fair market value
of the Company's Common Stock on the date of grant, as determined by
the Company's Compensation Committee.
(3) Options granted under the Equity Plan. These options become exercisable
as to 34% of the shares on April 3, 1997, 33% of the shares on
January 1, 1998, and the remaining 33% to vest on January 1, 1999.
AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND FISCAL YEAR-END OPTION
VALUES
The following table sets forth certain information concerning
exercisable and unexercisable stock options held by the Named Executive Officers
as of December 31, 1997. No options were exercised during the fiscal year ended
December 31, 1997 by any Named Executive Officer, except Mr. Gordon.
<TABLE>
<CAPTION>
SHARES NUMBER OF SECURITIES
ACQUIRED UNDERLYING VALUE OF UNEXERCISED
ON VALUE UNEXERCISED OPTIONS IN-THE-MONEY OPTIONS
EXERCISE(#) REALIZED($)(1) AT FISCAL YEAR-END(#)(1) AT FISCAL YEAR-END($)(2)
----------- -------------- ------------------------ ------------------------
Exercisable Unexercisable Exercisable Unexercisable
----------- ------------- ----------- -------------
<S> <C> <C> <C> <C> <C> <C>
Eric B. Gordon ................. 25,000 $389,375 138,244 290,576 $3,060,446 $6,432,771
11,100 $165,495
Joseph C. Hogan, Jr., Ph.D. .... 0 -- 11,968 23,232 $ 105,474 $ 204,744
James R. Fitzgerald, Jr. ....... 0 -- 16,539 45,341 $ 247,321 $ 704,278
</TABLE>
- ---------------------
(1) Based on the difference between the option exercise price of such
options and the closing price of the underlying Common Stock on the
date of exercise.
(2) Based on the difference between the option exercise price of such
options and the closing price of the underlying shares of Common Stock
on December 31, 1997 as reported by the Nasdaq National Market
($22.938).
- 10 -
<PAGE> 14
EXECUTIVE EMPLOYMENT AGREEMENTS
The Company has entered into employment agreements with Mr. Gordon and
Mr. Fitzgerald. The Company agreed to employ Mr. Gordon as President and Chief
Executive Officer of the Company, effective January 2, 1996, at an annual salary
of not less than $225,000. In connection with this agreement, Mr. Gordon was
granted options to acquire 387,434 shares of Common Stock at $0.80 per share,
which vest over four years, and options to acquire 77,486 shares of Common Stock
at $0.80 per share, which vested upon the achievement of certain milestones. Mr.
Gordon was also provided with moving and relocation allowances. The agreement
provides for continued employment until termination by either party. If Mr.
Gordon is terminated by the Company without cause, the agreement provides that
he will be entitled to receive his base salary, plus any benefits to which he is
entitled and any options granted to Mr. Gordon which would have otherwise
vested, for a period of up to six months following such termination of
employment. In July 1996, the Company also made a loan in the principal amount
of $250,000 to Mr. Gordon. In July 1997, the terms of the loan were amended to
extend the due dates for the payments of principal and interest. Prior to the
amendment, the principal amount of the loan were to be repaid in three equal
annual installments beginning in October 1997. Under the amended terms, the
principal amount and the accrued interest will be repaid in three equal
installments beginning in February 1998. The loan bears interest at the lowest
applicable federal rate of interest as published by the Internal Revenue
Service. In light of the achievement of certain milestones by Mr. Gordon, the
Company has forgiven the principal of $83,333 and interest thereon of $5,003 of
the first payment installment of approximately $106,004 which was due in
February 1998. The remaining principal of $166,667 and interest thereon is
currently outstanding.
Under Mr. Fitzgerald's Agreement, the Company agreed to employ Mr.
Fitzgerald as Vice President and Chief Financial Officer of the Company,
effective July 9, 1996, at an annual salary of not less than $150,000. In
connection with the agreement, Mr. Fitzgerald was granted options, which vest
over four years, to acquire 50,000 shares of Common Stock at $6.00 per share.
The agreement provides for continued employment until termination by either
party.
PROPOSAL TO AMEND THE EQUITY INCENTIVE PLAN
GENERAL
The Company's Amended and Restated 1994 Equity Incentive Plan (the
"Equity Plan") was readopted by the Board of Directors on October 17, 1994 and
amended June 25, 1996 and was readopted by the stockholders on August 15, 1996.
The Equity Plan was further amended by action of the Board of Directors on
September 9, 1996, which amendment was approved by the stockholders on September
11, 1996. On April 8, 1998, the Board of Directors amended and restated the
Equity Plan, subject to stockholder approval, to, among other things,
incorporate the amendment discussed below.
The purpose of the Equity Plan is to attract and retain key employees
and consultants of the Company and its affiliates. The Equity Plan provides for
the grant of incentive and nonstatutory stock options (the "Options") to
employees and consultants of the Company and its affiliates ("Eligible
Persons").
Currently, Options may be made under the Equity Plan for up to a total
of 3,200,000 shares of Common Stock, subject to adjustment for stock splits and
similar capital changes, to employees of the Company and, in the case of
nonstatutory options, to consultants of the Company or any Affiliate (as defined
in the Equity Plan) capable of contributing to the Company's performance.
As of April 2, 1998, 166 employees were eligible to participate in the
Equity Plan and Options to purchase an aggregate of 2,771,788 shares of Common
Stock had been granted. Pursuant to the Equity Plan, 520,922 restricted shares
of Common Stock have been issued, of which 53,969 restricted shares have been
cancelled. Options to purchase 146,081 shares had been cancelled, Options to
purchase 177,597 shares had been exercised, and Options to purchase 2,448,110
shares remained outstanding, leaving 107,340 shares available for new Options
under the Equity Plan. The closing price of the Company's Common Stock as
reported by the Nasdaq National Market on April 2, 1998 was $20.625.
- 11 -
<PAGE> 15
ADMINISTRATION AND ELIGIBILITY
Awards are made by the Compensation Committee which has been designated
by the Board of Directors to administer the Equity Plan. The Compensation
Committee may delegate to one or more officers the power to make awards under
the Equity Plan to persons other than officers of the Company who are subject to
the reporting requirements of Section 16 of the Securities Exchange Act of 1934
(the "Exchange Act").
Options under the Equity Plan are granted at the discretion of the
Compensation Committee, which determines the recipients and establishes the
terms and conditions of each award, including the exercise price, the form of
payment of the exercise price, the number of shares subject to Option and the
time at which such Options become exercisable. However, the exercise price of
any incentive stock option granted under the Equity Plan may not be less than
the fair market value of the Common Stock on the date of grant. The exercise
price of any nonstatutory stock option is determined by the Compensation
Committee.
FEDERAL INCOME TAX CONSEQUENCES RELATING TO STOCK OPTIONS
Incentive Stock Options. An optionee does not realize taxable income
upon the grant or exercise of an incentive stock option ("ISO") under the Equity
Plan. If the optionee does not dispose of shares issued upon exercise of an ISO
within two years from the date of grant or within one year from the date of
exercise, then, upon the sale of such shares, any amount realized in excess of
the exercise price is taxed to the optionee as mid-term or long-term capital
gain, and any loss sustained will be a mid-term or long-term capital loss. No
deduction would be allowed to the Company for Federal income tax purposes. The
exercise of ISOs gives rise to an adjustment in computing alternative minimum
taxable income that may result in alternative minimum tax liability for the
optionee. If shares of Common Stock acquired upon the exercise of an ISO are
disposed of before the expiration of the two-year and one-year holding periods
described above (a "disqualifying disposition"), the optionee would realize
ordinary income in the year of disposition in an amount equal to the excess (if
any) of the fair market value of the shares at exercise (or, if less, the amount
realized on a sale of such shares) over the exercise price thereof, and the
Company would be entitled to deduct such amount. Any further gain realized would
be taxed as a short-term, mid-term or long-term capital gain and would not
result in any deduction to the Company. A disqualifying disposition in the year
of exercise will generally avoid the alternative minimum tax consequences of the
exercise of an ISO.
Nonstatutory Stock Options. No income is realized by the optionee upon
the grant of a nonstatutory option. Upon exercise, the optionee realizes
ordinary income in an amount equal to the difference between the exercise price
and the fair market value of the shares on the date of exercise, and the Company
is entitled to a tax deduction for the same amount. Upon disposition of the
shares, appreciation or depreciation after the date of exercise is treated as a
short-term, mid-term or long-term capital gain or loss and will not result in
any deduction for the Company.
PROPOSED AMENDMENT TO THE EQUITY PLAN
The Board of Directors has voted, subject to approval of the
stockholders, to increase the number of shares of Common Stock that may be
subject to Awards under the Equity Plan by 1,500,000 shares to an aggregate of
4,700,000 shares, subject to adjustment for stock splits and similar capital
changes. This proposed amendment is intended to ensure that a sufficient number
of shares of Common Stock are available to be issued to Eligible Persons in the
future.
VOTED REQUIRED
The affirmative vote by the holders of a majority of the shares
present, or represented by proxy, and entitled to vote at the meeting is
required to approve the amendment to the Equity Plan. Broker non-votes will not
be counted as present or represented for this purpose. Abstentions will be
counted as present and entitled to vote and, accordingly, will have the effect
of a negative vote.
THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THIS PROPOSAL.
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<PAGE> 16
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
During the fiscal year ended December 31, 1997, the Company's
Compensation Committee consisted of Messrs. Dow and Ferguson. None of the
members of the Compensation Committee has been an officer or employee of the
Company.
Mr. Dow is a general partner of SRB Associates IV L.P., which is the
general partner of Sevin Rosen Fund IV L.P., a venture capital firm and a
principal stockholder of the Company. Mr. Ferguson is a general partner of Atlas
Venture Associates II, L.P., which is the general partner of Atlas Venture Fund
II, L.P., a venture capital firm and a principal stockholder of the Company. See
"Share Ownership."
On March 5, 1998, L. Patrick Gage, Ph.D., a director of the Company,
was appointed the President of Wyeth-Ayerst Pharmaceuticals ("Wyeth-Ayerst"), a
division of American Home Products Corporation ("American Home Products") after
the merger of American Home Products and Genetics Institute, Inc., of which Mr.
Gage was President. Wyeth-Ayerst and the Company entered into a collaborative
agreement in July 1997, pursuant to which Wyeth-Ayerst subscribed to the
Company's Mapping Array Program and has committed to a minimum number of
Directed Array Programs. Under the collaborative agreement, Wyeth-Ayerst will
pay ArQule up to approximately $28 million, which includes a $2 million equity
investment in ArQule to be paid in 1998 and further payments to ArQule
throughout the five year collaboration as development milestones are reached. In
addition, ArQule will be entitled to royalties from sales of any products
emanating from this collaboration.
Loan to Mr. Gordon. The Company, in July 1996, made a loan in the
amount of $250,000 to Eric B. Gordon, the President, Chief Executive Officer and
a director of the Company, which loan is secured by shares of Common Stock
issuable to Mr. Gordon upon the exercise of stock options. The payment terms of
the loan were amended in July 1997 to extend the due dates of the payments of
principal and interest. The loan is represented by a promissory note which is
now due and payable in three equal annual installments beginning in February
1998 and bears interest at the lowest applicable federal rate of interest as
published by the Internal Revenue Service. In light of the achievement of
certain milestones by Mr. Gordon, the Company has forgiven the principal of
$83,333 and interest of $5,003 of the first installment payment of approximately
$106,004, which was due in February 1998. The remaining principal of $166,667
and interest thereon is currently outstanding.
Loan to Dr. Hogan. The Company, in November 1995, made a loan in the
amount of $120,000 to Dr. Hogan. The loan is represented by a promissory note
and is secured by shares of Common Stock issuable to Dr. Hogan. The loan bears
interest at the lowest applicable federal rate of interest as published by the
Internal Revenue Service. The original principal amount of the loan is forgiven
at a rate of 25% per year on each anniversary date of the note as long as Dr.
Hogan is employed by the Company. As of April 2, 1998, $60,000 of the principal
amount of the loan has been forgiven by the Company. The remaining principal and
accrued interest is currently outstanding.
- 13 -
<PAGE> 17
SHARE OWNERSHIP
The following table and footnotes set forth certain information
regarding the beneficial ownership of the Company's Common Stock as of April 2,
1998, by (i) persons known by the Company to be beneficial owners of more than
5% of the Common Stock, (ii) the Named Executive Officers, (iii) the directors
and nominees for election as directors of the Company, and (iv) all current
executive officers and directors as a group.
<TABLE>
<CAPTION>
SHARES BENEFICIALLY OWNED (1)
----------------------------------------
5% STOCKHOLDERS NUMBER PERCENT
- --------------- --------- -------
<S> <C> <C>
Atlas Venture (2)..................................... 1,154,480 9.67%
222 Berkeley Street
Boston, MA 02116
Physica B.V. (3)...................................... 907,734 7.60%
C.J. van Houtenlaan, 36
1381 CD Weiss
The Netherlands
Sevin Rosen Fund IV L.P. (4).......................... 658,113 5.51%
13455 Noel Road, Suite 1670
Dallas, TX 75240
The Kaufman Fund, Inc. (5)............................ 700,000 5.86%
140 E. 45 Street, 43rd Floor
New York, NY 10017
DIRECTORS AND EXECUTIVE OFFICERS
- --------------------------------
Stephen M. Dow (6).................................... 728,427 5.94%
Allan R. Ferguson (7)................................. 682,137 5.56%
L. Patrick Gage, Ph.D. (8)............................ 6,000 *
Adrian de Jonge, Ph.D. (9)............................ 22,000 *
Michael Rosenblatt, M.D. (10)......................... 6,000 *
Eric B. Gordon (11)................................... 247,939 2.02%
Joseph C. Hogan, Jr., Ph.D. (12)...................... 599,955 4.89%
James R. Fitzgerald, Jr. (13)......................... 22,443 *
All current directors and executive officers
as a group (8 persons) (14)......................... 2,314,901 18.87%
</TABLE>
- ---------------------
* Indicates less than 1%
(1) The persons and entities named in the table have sole voting and
investment power with respect to the shares beneficially owned by them,
except as noted below. Share numbers include shares of Common Stock
issuable pursuant to the outstanding options that may be exercised
within sixty (60) days after April 2, 1998.
(2) Consists of (i) 664,310 shares owned by Atlas Venture Fund II, L.P.
("Atlas Venture Fund"), (ii) 375,311 shares owned by Atlas Venture
Europe Fund B.V. ("Atlas Europe"), and (iii) 114,859 shares owned by
Atlas InvesteringsGroep ("AIG," collectively, with Atlas Venture Fund
and Atlas Europe, "Atlas Venture"). The voting and investment
discretion over the shares owned by Atlas Venture Fund is exercised by
the general partners of Atlas Venture Associates II, L.P., its general
partner. The general partners of Atlas Venture Associates II, L.P. are
Allan R. Ferguson, Barry J. Fidelman, Jean-Francois Formela and
Christopher J. Spray. Because of this relationship, Allan R. Ferguson,
a director of the Company, shares voting and investment discretion over
such shares. Atlas Europe is a corporation wholly-owned by AIG. The
voting and investment discretion over the shares owned by Atlas Europe
is exercised by the managing director of AIG, Michiel A. de Haan. Three
officers of AIG, Gerard H. Montanus, Hans Bosman, and Jaap van
Hellemond, share voting and investment discretion with the managing
director over the shares held by Atlas Europe. AIG is also a limited
partner of Atlas Venture Fund.
- 14 -
<PAGE> 18
(3) The voting and investment discretion over the shares owned by Physica
B.V. is exercised by the sole director of Physica B.V., J.W.F. van
Ingen.
(4) The voting and investment discretion over the shares owned by Sevin
Rosen Fund IV L.P. ("Sevin Rosen") is exercised by the general partner
of SRB Associates IV L.P., its general partner. The general partners of
SRB Associates L.P. are Stephen M. Dow, Jon W. Bayless, Charles H.
Phipps, Dennis J. Gorman, and John V. Jaggers. Because of this
relationship, Stephen M. Dow, a director of the Company, shares voting
and investment discretion over such shares.
(5) Information regarding the shares of Common Stock owned by The Kaufman
Fund, Inc. is as of January 7, 1998 based on its Schedule 13G filed
with the Company.
(6) Consists of (i) 12,000 shares of Common Stock subject to options that
will become exercisable within sixty (60) days of April 2, 1998, (ii)
58,314 shares of Common Stock held in a family trust for the benefit of
Mr. Dow and his wife and (iii) 658,113 shares owned by or attributed to
Sevin Rosen. Mr. Dow is a general partner of SRB Associates IV L.P.
which is the general partner of Sevin Rosen. Mr. Dow disclaims
beneficial ownership of the shares owned by or attributed to Sevin
Rosen, except to the extent of his pecuniary interest therein. See
footnote (4).
(7) Includes (i) 12,000 shares of Common Stock subject to options that will
become exercisable within sixty (60) days of April 2, 1998 (assuming
Mr. Ferguson is re-elected as director of the Company at the 1998
Annual Meeting of Stockholders) and (ii) 664,310 shares owned by Atlas
Venture Fund. Mr. Ferguson is a general partner of Atlas Venture
Associates II, L.P., which is the general partner of Atlas Venture
Fund. Mr. Ferguson disclaims beneficial ownership of the shares owned
by Atlas Venture Fund, except to the extent of his pecuniary interest
therein. See footnote (2).
(8) Consists of 6,000 shares of Common Stock subject to options that will
become exercisable within sixty (60) days of April 2, 1998.
(9) Consists of (i) 12,000 shares of Common Stock subject to options that
will become exercisable within sixty (60) days of April 2, 1998 and
(ii) 10,000 shares of Common Stock owned by Dr. de Jonge's wife.
(10) Consists of 6,000 shares of Common Stock subject to options that will
become exercisable within sixty (60) days of April 2, 1998. Dr.
Rosenblatt was elected as a director of the Company on April 9, 1998.
(11) Includes (i) 235,103 shares of Common Stock subject to options that are
presently exercisable and (ii) 1,500 shares of Common Stock held in
trust for the benefit of his children.
(12) Consists of (i) 23,584 shares of Common Stock subject to options that
are presently exercisable, (ii) 458,973 shares held by The Hogan Family
Limited Partnership, of which Dr. Hogan and his wife are the general
partners, and (iii) 117,398 shares that represent Dr. Hogan's pro rata
ownership interest in the shares currently owned by Legomer
Technologies, Inc.
(13) Includes 20,460 shares of Common Stock subject to options that are
presently exercisable.
(14) Includes 327,147 shares of Common Stock subject to options that are
presently exercisable or will become exercisable within sixty (60) days
of April 2, 1998. See footnotes (6), (7), (8), (9), (10), (11), (12),
and (13).
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<PAGE> 19
SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
The Company's executive officers and directors are required under
Section 16(a) of the Exchange Act to file reports of ownership of Company
securities and changes in ownership with the Securities and Exchange Commission.
Copies of those reports must also be furnished to the Company.
Based solely on a review of the copies of reports furnished to the
Company and written representations that no other reports were required, the
Company believes that during 1997 the executive officers and directors of the
Company complied with all applicable Section 16(a) filing requirements, except
that Dr. de Jonge a director of the Company, reported in a Form 5 filed on
February 11, 1998 the purchase by his spouse of 10,000 shares of Common Stock,
for which a Form 4 was due on December 10, 1996.
INFORMATION CONCERNING AUDITORS
The firm of Price Waterhouse LLP, independent accountants, has audited
the Company's accounts since the inception of the Company and will do so for
1998. Representatives of Price Waterhouse LLP have been invited to attend the
Annual Meeting.
STOCKHOLDER PROPOSALS
The Company's Bylaws require a stockholder who wishes to bring business
before or propose director nominations at an annual meeting to give written
notice to the Secretary of the Company not less than 45 days nor more than 60
days before the meeting, unless less than 60 days' notice or public disclosure
of the meeting is given, in which case the stockholder's notice must be received
within 15 days after such notice or disclosure is given. The notice must contain
specified information about the proposed business or nominee and the stockholder
making the proposal or nomination. If any stockholder intends to present a
proposal at the 1999 Annual Meeting of Stockholders and desires that it be
considered for inclusion in the Company's proxy statement and form of proxy, it
must be received by the Company at 200 Boston Avenue, Medford, Massachusetts,
02155, attention: James R. Fitzgerald, Jr., no later than December 16, 1998.
OTHER MATTERS
The Board of Directors does not know of any business to come before the
meeting other than the matters described in the notice. If other business is
properly presented for consideration at the meeting, the enclosed proxy
authorizes the persons named therein to vote the shares in their discretion.
IN ADDITION TO THE COMPANY'S ANNUAL REPORT, WHICH HAS BEEN MAILED TO
STOCKHOLDERS, ANY HOLDER OR BENEFICIAL OWNER OF THE COMPANY'S COMMON STOCK MAY
OBTAIN A COPY OF THE COMPANY'S FORM 10-K FOR THE FISCAL YEAR ENDING DECEMBER 31,
1997, AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION. WRITTEN REQUESTS FOR
COPIES OF THE COMPANY'S FORM 10-K SHOULD BE ADDRESSED TO JAMES R. FITZGERALD,
JR., CHIEF FINANCIAL OFFICER, 200 BOSTON AVENUE, MEDFORD, MASSACHUSETTS, 02155.
- 16 -
<PAGE> 20
ARQULE, INC.
AMENDED AND RESTATED
1994 EQUITY INCENTIVE PLAN
As amended by the Board of Directors on April 8, 1998,
Subject to Stockholder Approval
Section 1. PURPOSE
This ArQule, Inc. Amended and Restated 1994 Equity Incentive Plan (the
"Plan") amends and restates the ArQule, Inc. Amended and Restated 1994 Equity
Incentive Plan by providing for the grant of equity incentives of various forms
in the Company. The purpose of the Plan is to attract and retain key employees
and consultants of the Company and its Affiliates, to provide an incentive for
them to achieve long-range performance goals, and to enable them to participate
in the long-term growth of the Company.
Section 2. DEFINITIONS
"Affiliate" means any business entity that directly, or indirectly
through one or more intermediaries, controls, is controlled by or is under
common control with the Company. For purposes hereof, "Control" (and with
correlative meanings, the terms "controlled by" and "under common control with")
shall mean the possession of the power to direct or cause the direction of the
management and policies of the Company, whether through the ownership of voting
stock, by contract or otherwise. In the case of a corporation "control" shall
mean, among other things, the direct or indirect ownership of more than fifty
percent (50%) of its outstanding voting stock.
"Award" means any Option, Stock Appreciation Right, Performance Share,
Restricted Stock, Stock Unit or Other Stock-Based Award awarded under the Plan
or any Award previously granted under the 1994 Equity Incentive Plan of the
Company or the Amended and Restated 1994 Equity Incentive Plan of the Company as
in effect prior to date this Plan was adopted by the Board of Directors.
"Board" means the Board of Directors of the Company.
"Code" means the Internal Revenue Code of 1986, as amended from time to
time, and any successor to such Code.
"Committee" means a committee of not less than two members of the Board
appointed by the Board to administer the Plan. If a Committee is authorized to
grant Options to a Reporting Person or a "covered employee" within the meaning
of Section 162(m) of the Code, each member shall be a "non-employee director" or
the equivalent within the meaning of Rule 16b-3 under the Securities Exchange
Act of 1934 and an "outside director" or the equivalent
<PAGE> 21
within the meaning of Section 162(m) of the Code, respectively. Until such
committee is appointed, "Committee" means the Board.
"Common Stock" or "Stock" means the Common Stock, $0.01 par value, of
the Company.
"Company" means ArQule, Inc.
"Designated Beneficiary" means the beneficiary designated by a
Participant, in a manner determined by the Committee, to receive amounts due or
exercise rights of the Participant in the event of the Participant's death. In
the absence of an effective designation by a Participant, "Designated
Beneficiary" shall mean the Participant's estate.
"Effective Date" means October 28, 1994.
"Fair Market Value" means, with respect to Common Stock or any other
property, the fair market value of such property as determined by the Committee
in good faith or in the manner established by the Committee from time to time.
"Incentive Stock Option" means an option to purchase shares of Common
Stock awarded to a Participant under Section 6 that is intended to meet the
requirements of Section 422 of the Code or any successor provision.
"Nonstatutory Stock Option" means an option to purchase shares of
Common Stock awarded to a Participant under Section 6 that is not intended to be
an Incentive Stock Option.
"Option" means an Incentive Stock Option or a Nonstatutory Stock
Option.
"Other Stock-Based Award" means an Award, other than an Option, Stock
Appreciation Right, Performance Share, Restricted Stock or Stock Unit, having a
Common Stock element and awarded to a Participant under Section 11.
"Participant" means a person selected by the Committee to receive an
Award under the Plan.
"Performance Cycle" or "Cycle" means the period of time selected by the
Committee during which performance is measured for the purpose of determining
the extent to which an award of Performance Shares has been earned.
"Performance Shares" mean shares of Common Stock, which may be earned
by the achievement of performance goals, awarded to a Participant under
Section 8.
"Reporting Person" means a person subject to Section 16 of the
Securities Exchange Act of 1934 or any successor provision.
"Restricted Period" means the period of time selected by the Committee
during which an Award may be forfeited to the Company pursuant to the terms and
conditions of such Award.
- 2 -
<PAGE> 22
"Restricted Stock" means shares of Common Stock subject to forfeiture
awarded to a Participant under Section 9.
"Stock Appreciation Right" or "SAR" means a right to receive any excess
in value of shares of Common Stock over the exercise price awarded to a
Participant under Section 7.
"Stock Unit" means an award of Common Stock or units that are valued in
whole or in part by reference to, or otherwise based on, the value of Common
Stock, awarded to a Participant under Section 10.
Section 3. ADMINISTRATION
The Plan shall be administered by the Committee. The Committee shall
have authority to adopt, alter and repeal such administrative rules, guidelines
and practices governing the operation of the Plan as it shall from time to time
consider advisable, and to interpret the provisions of the Plan. The Committee's
decisions shall be final and binding. To the extent permitted by applicable law,
the Committee may delegate to one or more executive officers of the Company the
power to make Awards to Participants who are not Reporting Persons or covered
employees and all determinations under the Plan with respect thereto, provided
that the Committee shall fix the maximum amount of such Awards for all such
Participants and a maximum for any one Participant.
Section 4. ELIGIBILITY
All employees and, in the case of Awards other than Incentive Stock
Options, and consultants of the Company or any Affiliate, capable of
contributing significantly to the successful performance of the Company, other
than a person who has irrevocably elected not to be eligible, are eligible to be
Participants in the Plan.
Section 5. STOCK AVAILABLE FOR AWARDS
(a) Subject to adjustment under subsection (b), Awards may be made
under the Plan for up to 4,700,000 shares of Common Stock. If any Award in
respect of shares of Common Stock expires or is terminated unexercised or is
forfeited without the Participant having had the benefits of ownership (other
than voting rights), the shares subject to such Award, to the extent of such
expiration, termination or forfeiture, shall again be available for award under
the Plan. Common Stock issued through the assumption or substitution of
outstanding grants from an acquired company shall not reduce the shares
available for Awards under the Plan. Shares issued under the Plan may consist in
whole or in part of authorized but unissued shares or treasury shares.
(b) In the event that the Committee determines that any stock
dividend, extraordinary cash dividend, creation of a class of equity securities,
recapitalization, reorganization, merger, consolidation, split-up, spin-off,
combination, exchange of shares, warrants or rights offering to purchase Common
Stock at a price substantially below fair market value, or other similar
transaction affects the Common Stock such that an adjustment is required in
order to preserve the benefits or potential benefits intended to be made
available under the Plan, then the
- 3 -
<PAGE> 23
Committee (subject, in the case of Incentive Stock Options, to any limitation
required under the Code) shall equitably adjust any or all of (i) the number and
kind of shares in respect of which Awards may be made under the Plan, (ii) the
number and kind of shares subject to outstanding Awards, and (iii) the award,
exercise or conversion price with respect to any of the foregoing, and if
considered appropriate, the Committee may make provision for a cash payment with
respect to an outstanding Award, provided that the number of shares subject to
any Award shall always be a whole number.
Section 6. STOCK OPTIONS
(a) Subject to the provisions of the Plan, the Committee may award
Incentive Stock Options and Nonstatutory Stock Options and determine the number
of shares to be covered by each Option, the option price therefor and the
conditions and limitations applicable to the exercise of the Option. The terms
and conditions of Incentive Stock Options shall be subject to and comply with
Section 422 of the Code or any successor provision and any regulations
thereunder, and no Incentive Stock Option may be granted hereunder more than ten
years after the Effective Date.
(b) The Committee shall establish the option price at the time each
Option is awarded, which price shall not be less than 100% of the Fair Market
Value of the Common Stock on the date of award with respect to Incentive Stock
Options. Nonstatutory Stock Options may be granted at such prices as the
Committee may determine.
(c) Each Option shall be exercisable at such times and subject to
such terms and conditions as the Committee may specify in the applicable Award
or thereafter. The Committee may impose such conditions with respect to the
exercise of Options, including conditions relating to applicable federal or
state securities laws, as it considers necessary or advisable.
(d) No shares shall be delivered pursuant to any exercise of an
Option until payment in full of the option price therefor is received by the
Company. Such payment may be made in whole or in part in cash or, to the extent
permitted by the Committee at or after the award of the Option, by delivery of a
note or shares of Common Stock owned by the optionee, including Restricted
Stock, or by retaining shares otherwise issuable pursuant to the Option, in each
case valued at their Fair Market Value on the date of delivery or retention, or
such other lawful consideration as the Committee may determine.
(e) The Committee may provide that, subject to such conditions as it
considers appropriate, upon the delivery or retention of shares to the Company
in payment of an Option, the Participant automatically be awarded an Option for
up to the number of shares so delivered.
Section 7. STOCK APPRECIATION RIGHTS
(a) Subject to the provisions of the Plan, the Committee may award
SARs in tandem with an Option (at or after the award of the Option), or alone
and unrelated to an Option. SARs
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<PAGE> 24
in tandem with an Option shall terminate to the extent that the related Option
is exercised, and the related Option shall terminate to the extent that the
tandem SARs are exercised. SARs granted in tandem with Options shall have an
exercise price not less than the exercise price of the related Option. SARs
granted alone and unrelated to an Option may be granted at such exercise prices
as the Committee may determine.
(b) An SAR related to an Option, which SAR can only be exercised upon
or during limited periods following a change in control of the Company, may
entitle the Participant to receive an amount based upon the highest price paid
or offered for Common Stock in any transaction relating to the change in control
or paid during the thirty-day period immediately preceding the occurrence of the
change in control in any transaction reported in the stock market in which the
Common Stock is normally traded.
Section 8. PERFORMANCE SHARES
(a) Subject to the provisions of the Plan, the Committee may award
Performance Shares and determine the number of such shares for each Performance
Cycle and the duration of each Performance Cycle. There may be more than one
Performance Cycle in existence at any one time, and the duration of Performance
Cycles may differ from each other. The payment value of Performance Shares shall
be equal to the Fair Market Value of the Common Stock on the date the
Performance Shares are earned or, in the discretion of the Committee, on the
date the Committee determines that the Performance Shares have been earned.
(b) The Committee shall establish performance goals for each Cycle,
for the purpose of determining the extent to which Performance Shares awarded
for such Cycle are earned, on the basis of such criteria and to accomplish such
objectives as the Committee may from time to time select. During any Cycle, the
Committee may adjust the performance goals for such Cycle as it deems equitable
in recognition of unusual or non-recurring events affecting the Company, changes
in applicable tax laws or accounting principles, or such other factors as the
Committee may determine.
(c) As soon as practicable after the end of a Performance Cycle, the
Committee shall determine the number of Performance Shares that have been earned
on the basis of performance in relation to the established performance goals.
The payment values of earned Performance Shares shall be distributed to the
Participant or, if the Participant has died, to the Participant's Designated
Beneficiary, as soon as practicable thereafter. The Committee shall determine,
at or after the time of award, whether payment values will be settled in whole
or in part in cash or other property, including Common Stock or Awards.
Section 9. RESTRICTED STOCK
(a) Subject to the provisions of the Plan, the Committee may award
shares of Restricted Stock and determine the duration of the Restricted Period
during which, and the conditions under which, the shares may be forfeited to the
Company and the other terms and conditions of such Awards. Shares of Restricted
Stock may be issued for no cash consideration or such minimum consideration as
may be required by applicable law.
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(b) Shares of Restricted Stock may not be sold, assigned,
transferred, pledged or otherwise encumbered, except as permitted by the
Committee, during the Restricted Period. Shares of Restricted Stock shall be
evidenced in such manner as the Committee may determine. Any certificates issued
in respect of shares of Restricted Stock shall be registered in the name of the
Participant and unless otherwise determined by the Committee, deposited by the
Participant, together with a stock power endorsed in blank, with the Company. At
the expiration of the Restricted Period, the Company shall deliver such
certificates to the Participant or if the Participant has died, to the
Participant's Designated Beneficiary.
Section 10. STOCK UNITS
(a) Subject to the provisions of the Plan, the Committee may award
Stock Units subject to such terms, restrictions, conditions, performance
criteria, vesting requirements and payment rules as the Committee shall
determine.
(b) Shares of Common Stock awarded in connection with a Stock Unit
Award shall be issued for no cash consideration or such minimum consideration as
may be required by applicable law.
Section 11. OTHER STOCK-BASED AWARDS
(a) Subject to the provisions of the Plan, the Committee may make
other awards of Common Stock and other awards that are valued in whole or in
part by reference to, or are otherwise based on, Common Stock, including without
limitation convertible preferred stock, convertible debentures, exchangeable
securities and Common Stock awards or options. Other Stock-Based Awards may be
granted either alone or in tandem with other Awards granted under the Plan
and/or cash awards made outside of the Plan.
(b) The Committee may establish performance goals, which may be based
on performance goals related to book value, subsidiary performance or such other
criteria as the Committee may determine, Restricted Periods, Performance Cycles,
conversion prices, maturities and security, if any, for any Other Stock-Based
Award. Other Stock-Based Awards may be sold to Participants at the face value
thereof or any discount therefrom or awarded for no consideration or such
minimum consideration as may be required by applicable law.
Section 12. GENERAL PROVISIONS APPLICABLE TO AWARDS
(a) Documentation. Each Award under the Plan shall be evidenced by a
writing delivered to the Participant specifying the terms and conditions thereof
and containing such other terms and conditions not inconsistent with the
provisions of the Plan as the Committee considers necessary or advisable to
achieve the purposes of the Plan or to comply with applicable tax and regulatory
laws and accounting principles.
(b) Committee Discretion. Each type of Award may be made alone, in
addition to or in relation to any other type of Award. The terms of each type of
Award need not be identical, and the Committee need not treat Participants
uniformly. Except as otherwise
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provided by the Plan or a particular Award, any determination with respect to an
Award may be made by the Committee at the time of award or at any time
thereafter.
(c) Settlement. The Committee shall determine whether Awards are
settled in whole or in part in cash, Common Stock, other securities of the
Company, Awards or other property. The Committee may permit a Participant to
defer all or any portion of a payment under the Plan, including the crediting of
interest on deferred amounts denominated in cash and dividend equivalents on
amounts denominated in Common Stock.
(d) Dividends and Cash Awards. In the discretion of the Committee,
any Award under the Plan may provide the Participant with (i) dividends or
dividend equivalents payable currently or deferred with or without interest, and
(ii) cash payments in lieu of or in addition to an Award.
(e) Termination of Employment. The Committee shall determine the
effect on an Award of the disability, death, retirement or other termination of
employment of a Participant and the extent to which, and the period during
which, the Participant's legal representative, guardian or Designated
Beneficiary may receive payment of an Award or exercise rights thereunder.
(f) Change in Control. In order to preserve a Participant's rights
under an Award in the event of a change in control of the Company, the Committee
in its discretion may, at the time an Award is made or at any time thereafter,
take one or more of the following actions: (i) provide for the acceleration of
any time period relating to the exercise or realization of the Award, (ii)
provide for the purchase of the Award upon the Participant's request for an
amount of cash or other property that could have been received upon the exercise
or realization of the Award had the Award been currently exercisable or payable,
(iii) adjust the terms of the Award in a manner determined by the Committee to
reflect the change in control, (iv) cause the Award to be assumed, or new rights
substituted therefor, by another entity, or (v) make such other provision as the
Committee may consider equitable and in the best interests of the Company.
(g) Loans. The Committee may authorize the making of loans or cash
payments to Participants in connection with any Award under the Plan, which
loans may be secured by any security, including Common Stock, underlying or
related to such Award (provided that such Loan shall not exceed the Fair Market
Value of the security subject to such Award), and which may be forgiven upon
such terms and conditions as the Committee may establish at the time of such
loan or at any time thereafter.
(h) Withholding Taxes. The Participant shall pay to the Company, or
make provision satisfactory to the Committee for payment of, any taxes required
by law to be withheld in respect of Awards under the Plan no later than the date
of the event creating the tax liability. In the Committee's discretion, such tax
obligations may be paid in whole or in part in shares of Common Stock, including
shares retained from the Award creating the tax obligation, valued at their Fair
Market Value on the date of delivery. The Company and its Affiliates may, to the
extent permitted by law, deduct any such tax obligations from any payment of any
kind otherwise due to the Participant.
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<PAGE> 27
(i) Foreign Nationals. Awards may be made to Participants who are
foreign nationals or employed outside the United States on such terms and
conditions different from those specified in the Plan as the Committee considers
necessary or advisable to achieve the purposes of the Plan or to comply with
applicable laws.
(j) Amendment of Award. The Committee may amend, modify or terminate
any outstanding Award, including substituting therefor another Award of the same
or a different type, changing the date of exercise or realization and converting
an Incentive Stock Option to a Nonstatutory Stock Option, provided that the
Participant's consent to such action shall be required unless the Committee
determines that the action, taking into account any related action, would not
materially and adversely affect the Participant.
(k) Transferability. In the discretion of the Committee, any Award
may be made transferable upon such terms and conditions and to such extent as
the Committee determines, provided that Incentive Stock Options may be
transferable only to the extent permitted by the Code. The Committee may in its
discretion waive any restriction on transferability.
Section 13. MISCELLANEOUS
(a) No Right To Employment. No person shall have any claim or right
to be granted an Award, and the grant of an Award shall not be construed as
giving a Participant the right to continued employment. The Company expressly
reserves the right at any time to dismiss a Participant free from any liability
or claim under the Plan, except as expressly provided in the applicable Award.
(b) No Rights As Stockholder. Subject to the provisions of the
applicable Award, no Participant or Designated Beneficiary shall have any rights
as a stockholder with respect to any shares of Common Stock to be distributed
under the Plan until he or she becomes the holder thereof. A Participant to whom
Common Stock is awarded shall be considered the holder of the Stock at the time
of the Award except as otherwise provided in the applicable Award.
(c) Effective Date. Subject to the approval of the stockholders of
the Company, the Plan shall be effective on the Effective Date. Before such
approval, Awards may be made under the Plan expressly subject to such approval.
(d) Amendment of Plan. The Board may amend, suspend or terminate the
Plan or any portion thereof at any time, subject to any stockholder approval
that the Board determines to be necessary or advisable.
(e) Governing Law. The provisions of the Plan shall be governed by
and interpreted in accordance with the laws of Delaware.
-----------------------------------------
This Plan was approved by the Board of Directors on April 8, 1998.
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This Plan shall be voted on by the stockholders at the Annual Meeting of
Stockholders scheduled for May 14, 1998.
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THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
ARQULE, INC.
PROXY FOR THE ANNUAL MEETING OF STOCKHOLDERS MAY 14, 1998
The undersigned stockholder of ArQule, Inc. (the "Company") hereby appoints
James R. Fitzgerald, Michael Lytton, and Lynnette C. Fallon, and each of them
acting singly, the attorneys and proxies of the undersigned, with full power of
substitution, to vote on behalf of the undersigned all the shares of capital
stock of the Company entitled to vote at the Annual Meeting of Stockholders of
the Company to be held on May 14, 1998, and at all adjournments thereof, hereby
revoking any proxy heretofore given with respect to such shares.
(Continued and to signed on the reverse side)
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SEE REVERSE
SIDE
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<PAGE> 30
Please date, sign and mail your
proxy card back as soon as possible!
Annual Meeting of Stockholders
ARQULE, INC.
May 14, 1998
Please Detach and Mail in the Envelope Provided
/X/ PLEASE MARK YOUR
VOTES AS IN THIS
EXAMPLE.
WITHHELD
FOR from both
both nominees nominees
1. Proposal / / / / Nominees: Allan R. Ferguson
to elect Joseph C. Hogan, Jr., Ph.D.
directors
FOR, except vote withheld from the following
nominees:
____________________________________________.
Signature______________________________________ Date_____________________, 1998
FOR AGAINST ABSTAIN
2. To approve an amendment to the Company's / / / / / /
Amended and Restated 1994 Equity Incentive
Plan to increase the aggregate number of
shares of the Company's common stock as to
which awards may be granted under such plan
by 1,500,000 shares.
This Proxy when properly executed will be voted in the manner directed herein
by the undersigned stockholders. If no specification is made, this proxy will
be voted for proposals 1 and 2. In their discretion, the proxies are also
authorized to vote upon such matters as may properly came before the meeting.
Signature______________________________________ Date_____________________, 1998
(IF HELD JOINTLY)
Note: Please sign exactly as name appears on stock certificate. When shares
are held by joint tenants, both should sign. When signing as attorney,
executor, administrator, trustee or guardian, please give full title as
such. If a corporation, please sign in full corporate name by President
or other authorized officer. If a partner, please sign in partnership
name by authorized person.
