Page 1 of 6 Pages
Exhibit Index Page 5
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. _______________)*
Human Genome Sciences, Inc.
______________________________________________________________________
(Name of Issuer)
Common Stock; $.01 Par Value
______________________________________________________________________
(Title of Class of Securities)
444903108
______________________________________________________________________
(CUSIP NUMBER)
Check the following box if a fee is being paid with this statement
( X ). (A fee is not required only if the filing person: (1) has a
previous statement on file reporting beneficial ownership of more than
five percent of the class of securities described in Item 1; and (2)
has filed no amendment subsequent thereto reporting beneficial
ownership of five percent or less of such class.) (See Rule 13d-7).
* The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject to the
liabilities of that section of the Act but shall be subject to all
other provisions of the Act (however, see the Notes).
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Page 2 of 6 Pages
CUSIP NO. 444903108 13G
1. NAME OF REPORTING PERSON
S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Aetna Life and Casualty Company
151 Farmington Avenue
Hartford, CT. 06156-3124 IRS Identification No. 06-0843808
______________________________________________________________________
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
(a)_________
N/A (b)_________
______________________________________________________________________
3. SEC USE ONLY
______________________________________________________________________
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Connecticut
______________________________________________________________________
5. SOLE VOTING POWER
847,500
_____________________________________
NUMBER OF SHARES BENEFICIALLY
OWNED BY EACH REPORTING
PERSON WITH
6. SHARED VOTING POWER
-0-
_____________________________________
7. SOLE DISPOSITIVE POWER
847,500
______________________________________
8. SHARED DISPOSITIVE POWER
-0-
______________________________________
_____________________________________________________________________
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
847,500
_____________________________________________________________________
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
N/A
_____________________________________________________________________
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.80%
_____________________________________________________________________
12. TYPE OF REPORTING PERSON*
HC
______________________________________________________________________
*SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE> Page 3 of 6 Pages
SCHEDULE 13G
Item 1(a). Name of Issuer:
Human Genome Sciences, Inc.
Item 1(b). Address of Issuer's Principal Executive Offices:
9620 Medical Center Drive
Suite 300
Rockville, MD. 20850-3338
Item 2(a). Name of Person Filing:
Aetna Life and Casualty Company
Item 2(b). Address of Principal Business Office or, if none,
Residence:
151 Farmington Avenue
Hartford, Connecticut 06156-3124
Item 2(c). Citizenship:
Connecticut
Item 2(d). Title of Class of Securities:
Common Stock; $.01 Par Value
Item 2(e). CUSIP Number:
444903108
Item 3. Statement filed pursuant to Rule 13d-1(b).
Parent Holding Company, in accordance with
Section 240.13d-1(b)(ii)(G).
Item 4. Ownership.
(a). Amount Beneficially Owned
847,500 shares of Common Stock, which includes
840,000 shares of Common Stock and 7,500 shares of
Common Stock issuable upon exercise of warrants.
(b). Percent of Class:
5.80%
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Page 4 of 6 Pages
(c). Number of shares as to which such person has:
(i) sole power to vote or to direct the vote -
847,500
(ii) shared power to vote or to direct the vote-
-0-
(iii) sole power to dispose or to direct the
disposition of - 847,500
(iv) shared power to dispose or to direct the
disposition of- -0-
Item 5. Ownership of Five Percent or Less of a Class.
N/A
Item 6. Ownership of More than Five Percent on Behalf of
Another Person.
N/A
Item 7. Identification and Classification of the Subsidiary
Which Acquired the Security Being Reported on By
the Parent Holding Company.
See attached Exhibit
Item 8. Identification and Classification of Members of the
Group.
N/A
Item 9. Notice of Dissolution of Group.
N/A
Item 10. Certification.
By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were acquired in the ordinary
course of business and were not acquired for the purpose of and do not
have the effect of changing or influencing the control of the issuer
of such securities and were not acquired in connection with or as a
participant in any transaction having such purposes or effect.
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true,
complete and correct.
February 8, 1994
__________________________ (For the year ended December 31, 1993)
Date
DANIEL P. KEARNEY
________________________________________
Signature
Daniel P. Kearney, Executive Vice President, Investments
Name/Title
Page 5 of 6 Pages
EXHIBIT INDEX
Page No. Identification and Classification of the Subsidiary
6 Which Acquired the Security Being Reported on by the
Parent Holding Company
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Page 6 of 6 Pages
EXHIBIT
Identification of the Relevant Subsidiary
The Aetna Casualty and Surety Company, an insurance company and
wholly-owned subsidiary of Aetna Life and Casualty Company.
847,500 shares of Common Stock; $.01 Par Value
