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<TABLE> <S> <C>
<ARTICLE> 9
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
SEPTEMBER 2000 FORM 10-Q FOR COMERICA INCORPORATED AND SUBSIDIARIES AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<S> <C>
<PERIOD-TYPE> 9-MOS
<FISCAL-YEAR-END> DEC-31-2000
<PERIOD-START> JAN-01-2000
<PERIOD-END> SEP-30-2000
<CASH> 1,519,051
<INT-BEARING-DEPOSITS> 28,898
<FED-FUNDS-SOLD> 103,758
<TRADING-ASSETS> 23,521
<INVESTMENTS-HELD-FOR-SALE> 2,692,595
<INVESTMENTS-CARRYING> 0
<INVESTMENTS-MARKET> 0
<LOANS> 35,035,419
<ALLOWANCE> 523,575
<TOTAL-ASSETS> 40,885,390
<DEPOSITS> 25,519,938
<SHORT-TERM> 3,285,429
<LIABILITIES-OTHER> 583,792
<LONG-TERM> 7,650,541
0
250,000
<COMMON> 786,166
<OTHER-SE> 2,809,524
<TOTAL-LIABILITIES-AND-EQUITY> 40,885,390
<INTEREST-LOAN> 2,231,971
<INTEREST-INVEST> 140,065
<INTEREST-OTHER> 28,082
<INTEREST-TOTAL> 2,400,118
<INTEREST-DEPOSIT> 572,154
<INTEREST-EXPENSE> 1,163,875
<INTEREST-INCOME-NET> 1,236,243
<LOAN-LOSSES> 113,000
<SECURITIES-GAINS> 621
<EXPENSE-OTHER> 893,425
<INCOME-PRETAX> 852,669
<INCOME-PRE-EXTRAORDINARY> 555,108
<EXTRAORDINARY> 0
<CHANGES> 0
<NET-INCOME> 555,108
<EPS-BASIC> 3.47
<EPS-DILUTED> 3.43
<YIELD-ACTUAL> 4.46
<LOANS-NON> 236,021
<LOANS-PAST> 53,338
<LOANS-TROUBLED> 299
<LOANS-PROBLEM> 0
<ALLOWANCE-OPEN> 476,470
<CHARGE-OFFS> 77,516
<RECOVERIES> 11,679
<ALLOWANCE-CLOSE> 523,575
<ALLOWANCE-DOMESTIC> 279,362
<ALLOWANCE-FOREIGN> 48,277
<ALLOWANCE-UNALLOCATED> 195,936
</TABLE>
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