MERRILL LYNCH SERIES FUNDS INC
497, 2001-01-19
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                         MERRILL LYNCH SERIES FUND, INC.

                    Supplement dated January 19, 2001 to the
             Statement of Additional Information dated April 4, 2000

         The  following   information   supersedes  and  replaces  any  contrary
information  contained in the  Statement  of  Additional  Information  under the
caption "Portfolio Strategies--Transactions in Options, Futures and Currency."

         Effective  today,  each of the  Portfolios  (except  the Money  Reserve
Portfolio)  may engage in  options,  futures  and  options on futures to enhance
total return as well as for hedging purposes.



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