MACROCHEM CORP
SC 13D, 1998-03-30
PHARMACEUTICAL PREPARATIONS
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SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934
(Amendment No.    )*

MACROCHEM CORPORATION
________________________________________________________________________
(Name of Issuer)

Common Stock  Par value $.01
________________________________________________________________________
(Title of Class of Securities)

555903103
________________________________________________________________________
(CUSIP Number)

Paul F. Byrne c/o Janssen-Meyers Associates, L.P. 17 State Street, 
NY, NY 10004 	 (212) 742-4200
________________________________________________________________________
(Name, Address  and Telephone Number of Person Authorized to 
Receive Notices and Communications)

12/31/97
________________________________________________________________________
(Date of Event which Requires Filing of this Statement)


If the filing person has previously filed a statement on Schedule 13G to
 report the acquisition which is the subject of this Schedule 13D, and
 is filing this schedule because of Rule 13d-1(b)(3) or (4), check the
 following box_____.

Check the following box if a fee is being paid with the statement _____. 
(A fee is not required only if the reporting person: (1) has a previous 
statement on file reporting beneficial ownership of more than five percent of
 the class of securities described in Item1; and (2)  has filed no amendment
 subsequent thereto reporting beneficial ownership of five percent of less 
of such class.)   (Sec Rule 13d-7.)

Note:  Six copies of this statement, including all exhibits, should be filed 
with the Commission.  See Rule 13d-1(a) for other parties to whom copies 
are to be sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities,
 and for 
any subsequent amendment containing information which would alter disclosures
 provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
 to be "filed" for the purpose of Section 18 of the Securities Exchange Act
 of 1934 
("Act") or otherwise subject to the liabilities of that section of the Act
 but shall be
subject to all other provisions of the Act (however, see the Notes).


1. Name of Reporting Person
Peter Janssen
_____________________________________________________
S.S. or I.R.S. Identification No. of Above Person

				SS # ###-##-####
	_____________________________________________________


2. Check the Appropriate Box if a Member of a Group 
(See Instructions before filling out)

a.________	b_______

	

3. SEC USE ONLY

_____________________________________________________

4. Source of Funds (See instructions before filling out).

______________________________________________________

5. Check Box if Disclosure of Legal Proceedings is Required 
Pursuant to Items           
     2(d) or 2(e).		

	_____________________________________________________________________________

6. Citizenship or Place of Organization

USA     
____________________________________________________

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH
REPORTING PERSON
(Questions 7 - 10)

7.  Sole Voting Power
1,585,667
____________________________________________________

8. Shared Voting Power

 
_____________________________________________________


9. Sole Dispositive Power

 1,585,667
_____________________________________________________

10. Shared Dispositive Power
 
_____________________________________________________

11.  Aggregate Amount Beneficially Owned by Each Reporting Person

 1,585,667
_____________________________________________________

12.  Check Box if the Aggregate Amount in Row (11) 
Excludes Certain Shares (See instructions before filling out)

_____________________________________________________



13. Percent of Class Represented by Amount in Row (11)

7.2%
______________________________________________________

14. Type of Reporting Person (See instructions before filling out)

 
______________________________________________________



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