SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D
Under the Securities Exchange Act of 1934
(Amendment No. )*
MACROCHEM CORPORATION
________________________________________________________________________
(Name of Issuer)
Common Stock Par value $.01
________________________________________________________________________
(Title of Class of Securities)
555903103
________________________________________________________________________
(CUSIP Number)
Paul F. Byrne c/o Janssen-Meyers Associates, L.P. 17 State Street, NY, NY 10004
(212) 742-4200
________________________________________________________________________
(Name, Address and Telephone Number of Person Authorized to Receive Notices
and
Communications)
12/31/97
________________________________________________________________________
(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report
the acquisition
which is the subject of this Schedule 13D, and is filing this schedule because
of Rule
13d-1(b)(3) or (4), check the following box_____.
Check the following box if a fee is being paid with the statement _____.
(A fee is not required only if the reporting person: (1) has a previous
statement
on file reporting beneficial ownership of more than five percent of
the class of
securities described in Item1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of five percent of less of such class.)
(Sec Rule 13d-7.)
Note: Six copies of this statement, including all exhibits, should be filed
with the Commission. See Rule 13d-1(a) for other parties to whom copies
are to be sent.
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of
securities, and
for
any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the
Act but shall be subject to all other provisions of the Act (however,
see the Notes).
1. Name of Reporting Person
Bruce Meyers
_____________________________________________________
S.S. or I.R.S. Identification No. of Above Person
_____________________________________________________
2. Check the Appropriate Box if a Member of a Group
(See Instructions before filling out)
a.________ b_______
3. SEC USE ONLY
_____________________________________________________
4. Source of Funds (See instructions before filling out).
______________________________________________________
5. Check Box if Disclosure of Legal Proceedings is Required
Pursuant to Items
2(d) or 2(e).
__________________________________________________________________________
___
6. Citizenship or Place of Organization
USA
____________________________________________________
NUMBER OF SHARES BENEFICIALLY OWNED BY
EACH REPORTING PERSON
(Questions 7 - 10)
7. Sole Voting Power
1,049,416
____________________________________________________
8. Shared Voting Power
_____________________________________________________
9. Sole Dispositive Power
1,049,416
_____________________________________________________
10. Shared Dispositive Power
_____________________________________________________
11. Aggregate Amount Beneficially Owned by Each Reporting Person
1,049,416
_____________________________________________________
12. Check Box if the Aggregate Amount in Row (11)
Excludes Certain Shares (See instructions before filling out)
_____________________________________________________
13. Percent of Class Represented by Amount in Row (11)
4.77%
______________________________________________________
14. Type of Reporting Person (See instructions before filling out)
______________________________________________________
