T CELL SCIENCES INC
DEF 14A, 1997-04-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                             [LOGO] T CELL
                                    SCIENCES

                              T Cell Sciences, Inc.

                                ----------------

                    Notice of Annual Meeting of Stockholders

                                ----------------

     The Annual Meeting of Stockholders of T Cell Sciences, Inc. will be held at
State Street Bank and Trust Company, 225 Franklin Street, Boston, Massachusetts,
02110 on Tuesday, May 13, 1997 at 2:00 P.M., for the following purposes: 


     1. To elect seven directors to serve until the 1998 Annual Meeting of
        Stockholders and until their successors are duly elected and
        qualified. 

     2. To transact any other business which may properly come before the
        meeting. 

     Stockholders of record at the close of business on April 1, 1997 will be
entitled to notice of and to vote at the meeting. Stockholders who are unable to
attend the meeting in person are requested to complete, date and return the
enclosed form of proxy in the envelope provided. No postage is required if
mailed in the United States. 

     A copy of the Company's Annual Report to Stockholders for the fiscal year
ended December 31, 1996 is being mailed to you with this Notice and Proxy
Statement. 

                                          NORMAN W. GORIN 
                                          Secretary 


Needham, Massachusetts

April 15, 1997 

                             YOUR VOTE IS IMPORTANT.

     WHETHER OR NOT YOU PLAN TO ATTEND THE ANNUAL MEETING, YOU ARE URGED TO
     DATE, SIGN AND PROMPTLY RETURN YOUR PROXY SO THAT YOUR SHARES MAY BE VOTED
     IN ACCORDANCE WITH YOUR WISHES. 


<PAGE>


                              T CELL SCIENCES, INC.
                                119 Fourth Avenue
                          Needham, Massachusetts 02194

                                ----------------

                                 PROXY STATEMENT

                                ----------------

                                  INTRODUCTION

     This Proxy Statement is furnished to the holders of Common Stock, par value
$.001 per share, ("Common Stock") of T Cell Sciences, Inc. (the "Company") in
connection with the solicitation of proxies on behalf of the Board of Directors
of the Company for use at the 1997 Annual Meeting of Stockholders to be held on
May 13, 1997, or at any adjournment thereof, pursuant to the accompanying Notice
of Annual Meeting of Stockholders. A form of proxy for use at the meeting and a
return envelope for the proxy are enclosed. Stockholders may revoke the
authority granted by their execution of proxies at any time before the proxies
are voted by filing with the Secretary of the Company a written revocation or
duly executed proxy, bearing a later date, or by voting in person at the
meeting. 

     The purpose of the meeting is to (i) elect seven directors to serve until
the 1998 Annual Meeting of Stockholders and until their successors are duly
elected and qualified and (ii) transact any other business which may properly
come before the meeting. The Company is not currently aware of any other matters
which will come before the meeting. If any other matters properly come before
the meeting, the persons designated as proxies intend to vote in accordance with
their best judgment on such matters. Shares represented by executed and
unrevoked proxies will be voted FOR the proposal shown on the form of proxy
unless otherwise indicated on the form of proxy. 

     Stockholders of record at the close of business on April 1, 1997 (the
"Record Date") will be entitled to vote at the meeting. The Company had
outstanding on the Record Date, 24,948,383 shares of Common Stock, each of which
is entitled to one vote upon each of the matters to be presented at the meeting.
The presence of holders of a majority of shares of Common Stock, whether in
person or by proxy, will constitute a quorum at the meeting. Abstentions, votes
withheld for director nominees and "broker non-votes" (that is, shares
represented at the meeting which are held by a broker or nominee and as to which
(i) instructions have not been received from the beneficial owner or the person
entitled to vote and (ii) the broker or nominee does not have discretionary
voting power) shall be treated as shares that are present and entitled to vote
with respect to matters presented at the meeting for purposes of determining
whether a quorum is present. With respect to the election of directors, the
by-laws of the Company (the "By-Laws") provide that such election shall be
determined by a plurality of votes cast by stockholders and thus shares
represented by a proxy that withholds authority to vote for a particular nominee
or nominees and broker non-votes will have no effect on the outcome of voting
for the election of directors. 

     Proxies for use at the meeting are being solicited by the Board of
Directors of the Company. Forms of proxies will be mailed to stockholders with
this Proxy Statement on or about April 15, 1997. Proxies will be solicited
chiefly by mail, but additional solicitation may be made by telephone or
telecopy by the officers, regular employees or agents of the Company. All
solicitation expenses, including costs of preparing, assembling and mailing the
proxy material, will be borne by the Company. 


                                       1

<PAGE>

                      BENEFICIAL OWNERSHIP OF COMMON STOCK

     The following table sets forth information regarding Common Stock ownership
by (i) each person known by the Company to own beneficially more than 5% of the
Company's outstanding Common Stock as of December 31, 1996, and (ii) by each
director and nominee for director, by each named executive officer, and by all
directors and executive officers as a group as of the Record Date. 

<TABLE>
<CAPTION>
                                                                                       Amount and                          
                                                                                        Nature of                          
Name and Address of                                                                     Beneficial         Percentage of   
 Beneficial Owners                                                                     Ownership(1)        Common Stock(2) 
- -------------------                                                                    ------------        ---------------
<S>                                                                                    <C>                      <C> 
James D. Grant  .........................................................              201,555 (3)               *         
 860 Fifth Avenue                                                                                                          
 New York, New York 10021                                                                                                  
Patrick C. Kung, Ph.D.   ................................................              758,960 (4)              3.0%       
 T Cell Sciences, Inc.                                                                                                     
 119 Fourth Avenue                                                                                                         
 Needham, Massachusetts 02194                                                                                              
John P. Munson  .........................................................               40,000 (5)               *         
 1 Heathlands Drive                                                                                                        
 Maidenhead                                                                                                                
 Berkshire SL6 4NF                                                                                                         
 ENGLAND                                                                                                                   
Thomas R. Ostermueller   ................................................               15,000 (6)               *         
 V.I. Technologies, Inc.                                                                                                   
 155 Duryea Road                                                                                                           
 Melville, New York 11747                                                                                                  
Harry H. Penner, Jr.  ...................................................               10,000                   *         
 Neurogen Corporation                                                                                                      
 35 Northeast Industrial Road                                                                                              
 Branford, Connecticut 06405                                                                                               
John Simon   ............................................................              171,107 (7)               *         
 Allen & Company Incorporated                                                                                              
 711 Fifth Avenue                                                                                                          
 New York, New York 10022                                                                                                  
Una S. Ryan  ............................................................              137,673 (6)               *         
 T Cell Sciences, Inc.                                                                                                     
 119 Fourth Avenue                                                                                                         
 Needham, Massachusetts 02194                                                                                              
Norman W. Gorin    ......................................................               26,250 (6)               *         
 T Cell Sciences, Inc.                                                                                                     
 119 Fourth Avenue                                                                                                         
 Needham, Massachusetts 02194                                                                                              
James L. Levin, D.V.M.   ................................................               45,857 (8)               *         
 T Cell Sciences, Inc.                                                                                                     
 119 Fourth Avenue                                                                                                         
 Needham, Massachusetts 02194                                                                                              
All directors and officers as a group (consisting of 9 persons)       ...            1,406,402 (9)             5.5%        
</TABLE>

- ---------------- 
*  Less than 1%. 

(1) Unless otherwise indicated, the persons shown have sole voting and
    investment power over the shares listed. 

(2) Common Stock includes all outstanding Common Stock plus, as required for the
    purpose of determining beneficial ownership (in accordance with Rule
    13d-3(d)(1) of the Securities Exchange Act of 1934, as amended), all Common
    Stock subject to any right of acquisition, through exercise or conversion 
    of any security, within 60 days of the Record Date. 

(3) Includes 11,000 shares held by Mr. Grant's wife, as to which he disclaims
    beneficial ownership, and 135,000 shares of Common Stock issuable upon
    exercise of stock options, which are exercisable within 60 days of the 
    Record Date. 

                                        2

<PAGE>

(4) Includes 255,000 shares held by Dr. Kung's wife, as to which he disclaims
    beneficial ownership, and 192,626 shares of Common Stock issuable upon
    exercise of stock options which are exercisable within 60 days of the Record
    Date. Excludes shares held by a trust for his minor children which is
    administered by disinterested trustees, excludes shares held by a custodian
    for his mother and excludes shares held by a charitable trust established by
    Dr. Kung and his wife. 

(5) Includes 25,000 shares of Common Stock issuable upon exercise of stock
    options which are exercisable within 60 days of the Record Date. 

(6) Consists solely of shares of Common Stock issuable upon exercise of stock
    options which are exercisable within 60 days of the Record Date. 

(7) Includes 55,000 shares of Common Stock issuable upon exercise of stock
    options which are exercisable within 60 days of the Record Date. Excludes
    300,528 shares of Common Stock beneficially owned by Allen & Company
    Incorporated as of the Record Date, as to which Mr. Simon disclaims
    beneficial ownership. 

(8) Includes 45,357 shares of Common Stock issuable upon exercise of stock
    options which are exercisable within 60 days of the Record Date. 

(9) Includes 631,906 shares of Common Stock issuable upon exercise of stock
    options which are exercisable within 60 days of the Record Date. 

                        PROPOSAL 1--ELECTION OF DIRECTORS

     Seven directors, constituting the entire Board of Directors, are to be
elected at the meeting. Each of the nominees listed below has consented to be
nominated and to serve if elected. The directors are elected by a plurality of
the votes cast at the meeting. Unless otherwise specified, the enclosed proxy
will be voted in favor of the nominees named below, all of whom are now
directors of the Company. In the event that a vacancy may occur during the year,
such vacancy may be filled by the Board of Directors for the remainder of the
full term. All nominees will be elected to serve until the next Annual Meeting
of Stockholders and until their successors are duly elected and qualified. In
the event any of these nominees shall be unable to serve as a director, the
shares represented by the proxy will be voted for the person, if any, who is
designated by the Board of Directors to replace the nominee. 

     The nominees for the Board of Directors, their ages, the year in which each
first became a director and their principal occupations during the past five
years are: 

<TABLE>
<CAPTION>
                                           Year First                     Principal Occupation                  
 Nominee                         Age    Became Director                During the Past Five Years               
- ---------                       ------  ---------------                --------------------------               
<S>                               <C>         <C>          <C>                                                     
James D. Grant (1)                64          1986         Chairman of the Board from November 1986 to          
                                                           date and Chief Executive Officer of the Company      
                                                           from November 1986 to February 1992 and from         
                                                           May 1996 to August 1996. Vice President,             
                                                           Scientific Development of CPC International, Inc.    
                                                           from 1973 to October 1986. From 1969 to 1987,        
                                                           Mr. Grant served as Deputy Commissioner of the       
                                                           U.S. Food and Drug Administration and served as      
                                                           Vice Chairman of an FDA Advisory Committee,          
                                                           the "Edwards Commission." Director of Targeted       
                                                           Genetics Corp. (U.S.), International Biotechnology   
                                                           Trust (U.K.), and Biocompatibles, Ltd. (U.K.).       

Patrick C. Kung, Ph.D. (1)        49          1984         Vice Chairman of the Board of the Company from       
                                                           February 1989 to date and Director since February    
                                                           1984. Scientific Director from February 1984 to      
                                                           August 1992. Since June 1994, President of           
                                                           Global Pharma Ltd., a Bermuda limited liability      
                                                           company, of which the Company holds a minority       
                                                           interest. Vice President of Research for Centocor,   
                                                           Inc. from 1981 to January 1984. Director of Asian    
                                                           American Bank & Trust Co. and Microbix               
                                                           Biosystems.                                          

                                        3

<PAGE>

                                          Year First                     Principal Occupation                   
 Nominee                         Age    Became Director                During the Past Five Years               
- ---------                       ------  ---------------                --------------------------               
John P. Munson (3)                62          1992         Private investor since April 1992 retirement         
                                                           from positions as Senior Vice President of Syntex    
                                                           Corporation and President of Syntex Pharmaceuticals  
                                                           International Ltd. Served in various management      
                                                           capacities at Syntex since 1969.                     

Thomas R. Ostermueller (2)(3)     48          1994         President, Chief Executive Officer and Director,     
                                                           V.I. Technologies, Inc. (formerly Melville           
                                                           Biologics, Inc.) since February 1995; previously     
                                                           Chief Operating Officer, Executive Vice President    
                                                           and member of the Board of Trustees of the New       
                                                           York Blood Center since February 1993. Executive     
                                                           Vice President of the Mead Johnson Nutritional       
                                                           Group, Bristol-Myers Squibb from 1990 to 1993        
                                                           and Vice President of Bristol-Myers from July        
                                                           1988 until 1990.                                     

Harry H. Penner, Jr.              51          1997         President, Chief Executive Officer and Director      
                                                           of Neurogen Corporation since December 1993;         
                                                           previously Executive Vice President of Novo          
                                                           Nordisk A/S and President of Novo Nordisk of         
                                                           North America, Inc. from 1988 to 1993. Executive     
                                                           Vice President and General Counsel of Novo           
                                                           Nordisk A/S from 1985 to 1988. Chairman of the       
                                                           Board of Directors for the Connecticut Technology    
                                                           Council, Advisory Board Member of Connecticut        
                                                           United for Research Excellence, Director of the      
                                                           Connecticut Business and Industry Associates and     
                                                           serves on the Board of Anergen, Inc.                 

Una S. Ryan, Ph.D. (1)            55          1996         Chief Executive Officer of the Company since         
                                                           August 13, 1996 and President, Chief Operating       
                                                           Officer and Director of the Company since May 29,    
                                                           1996. Dr. Ryan joined the Company as Vice            
                                                           President, Research and Chief Scientific Officer     
                                                           in May 1993. She is also Research Professor of       
                                                           Medicine at the Whitaker Cardiovascular Institute of 
                                                           the Boston University School of Medicine. Dr. Ryan   
                                                           held the position of Director of Health Sciences at  
                                                           Monsanto Co. from January 1990 to November 1992      
                                                           and was Research Professor of Surgery, Medicine      
                                                           and Cell Biology at Washington University School     
                                                           of Medicine from 1990 to 1993. From 1967 to 1990,    
                                                           Dr. Ryan was employed by the University of Miami,    
                                                           including most recently as Chief, Division of        
                                                           Vascular Cell Biology and Professor of Medicine.     

John Simon (2)                    54          1985         Executive Vice President and a Managing Director     
                                                           of Allen & Company Incorporated, a registered        
                                                           broker-dealer and investment banking firm, for       
                                                           more than five years. Director of Immune             
                                                           Response Corporation, Lunn Industries, Inc.,         
                                                           Neurogen Corporation and Batteries Batteries, Inc.   
</TABLE>

- -------------- 
(1) Member of the Executive Committee.
(2) Member of the Compensation Committee.
(3) Member of the Audit Committee. 


     The Board of Directors has an Audit Committee, a Compensation Committee and
an Executive Committee. The Board of Directors has no nominating committee. The
primary function of the Audit Committee is to review the scope and results of
the Company's annual audit, the fee charged by the Company's independent
accountants and matters relating to internal control procedures and systems. The
primary function of the Compensation Committee is to assist the Board in the
establishment of compensation for the Chief Executive Officer and, upon her 


                                        4

<PAGE>

recommendation, to approve the compensation of other officers and senior
employees and to approve certain other personnel and employee benefit matters.
The Executive Committee has the power to act on behalf of the Board, except for
certain powers excluded by the Company's By-Laws and the Delaware General
Corporation Law. 

     During the year ended December 31, 1996, the Board of Directors held eleven
meetings, the Audit Committee held two meetings, and the Compensation Committee
held one meeting, and each director attended at least 75% of the meetings held
by the Board and the Board committee on which he or she served during the period
he or she was a director. There were no meetings held by the Executive Committee
during the year. 

Director Compensation 

     Directors who are not employees of the Company are each entitled to receive
a retainer fee of $5,000 each fiscal year, except the Chairman of the Board who
receives a total fee of $30,000. Each Board committee Chairman receives an
additional retainer fee of $5,000. In addition, each member is entitled to
receive $1,000 for attendance at each meeting of the Board of Directors and $500
for attendance at each meeting of a Board committee. The Company's Amended and
Restated 1991 Stock Compensation Plan provides for annual non-discretionary
grants to each non-employee director of a stock option to purchase 5,000 shares
of Common Stock with vesting after one year, a ten year term and an exercise
price equal to the fair market value of the Common Stock on the day of grant. As
of the Record Date, the current non-employee directors had the following stock
options outstanding: James D. Grant--185,000 (includes grants received when an
executive officer); Patrick Kung--192,626 (includes grants received when an
executive officer); John P. Munson--45,000; Thomas R. Ostermueller--35,000;
Harry H. Penner, Jr.--20,000; and John Simon--55,000. 

Certain Transactions with Directors 

     Mr. James Grant, an executive officer of the Company until November 1,
1992, was a consultant to the Company in the areas of government affairs and
regulation and special projects until November 1, 1995. Mr. Grant is now a
consultant to the Company under a three-year agreement dated May 28, 1996 for
which he is expected to be paid $30,000 annually. Dr. Patrick Kung, an employee
of the Company until December 31, 1995, was a consultant to the Company under a
one-year agreement dated January 1, 1996 for which he was paid $30,000 in 1996.
Dr. Kung is now a consultant to the Company under a one-year agreement dated
January 1, 1997 for which he is expected to be paid $30,000. 

     Management believes that the services provided by Mr. Grant and Dr. Kung
were or will be beneficial to the Company and on terms consistent with those
offered by nonaffiliated sources. 

                                   MANAGEMENT

Executive Officers 

     The following table lists the name, age, position and offices of all
current executive officers of the Company. Officers are elected annually by the
Board of Directors until their successors are duly elected and qualified. 

<TABLE>
<CAPTION>
       Name of Individual          Age            Position and Offices                        
       ------------------          ---            --------------------                        
 <S>                               <C>   <C>                                                  
 Una S. Ryan, Ph.D.    .........   55    President and Chief Executive Officer                
 Norman W. Gorin    ............   44    Vice President, Finance and Chief Financial Officer  
 James L. Levin, D.V.M.   ......   42    Vice President of Development                        
</TABLE>

     For a biographical summary of Dr. Ryan, see "Election of Directors." 

     Norman W. Gorin was appointed Vice President, Finance and Chief Financial
Officer by the Board of Directors on May 21, 1996. Mr. Gorin joined the Company
from USTrust of Boston, the commercial banking subsidiary of UST Corp., where he
served for more than nine years, most recently in the positions of Senior Vice
President, Corporate Planning, and Senior Vice President, Marketing. Prior to US
Trust, Mr. Gorin served as Senior Vice President, Finance, of Sotheby's Inc.,
the New York-based fine art auctioneer, and as a Vice President and Manager with
Citicorp's Financial and Information Services and Merchant Banking groups. Mr.
Gorin was awarded a Masters Degree 

                                        5

<PAGE>

in Business Administration from the Wharton School at the University of
Pennsylvania and received a B.A. with Honors from Harvard College. 

     James L. Levin, D.V.M. joined the Company as Director of Pharmaceutical
Evaluation in April 1992 and has been Vice President of Development since
December 1995. Prior to joining the Company, he was Vice President, Technical
Operations for TSI Mason Laboratories in Worcester. He received a D.V.M. from
Tufts University School of Veterinary Medicine and an MS in pharmacology from
Tulane University. Dr. Levin is also an Adjunct Assistant Professor in the
Department of Comparative Medicine at Tufts University School of Veterinary
Medicine, as well as member of the Massachusetts Society for Medical Research. 

Summary Compensation Table 

     The following table shows, for the fiscal years ended December 31, 1996
("1996"), December 31, 1995 ("1995") and December 31, 1994 ("1994"), the cash
compensation paid by the Company, as well as other compensation paid or accrued
for these fiscal years, to the Chief Executive Officer and each person who
served as executive officers in 1996. 


<TABLE>
<CAPTION>
                                                                            Long-Term                                
                                                                           Compensation                              
                                                                        -------------------                          
                                              Annual Compensation             Awards                                 
                                           ------------------------     -------------------                          
                                                                            Securities                               
                                                                            Underlying                               
                                                                              Stock                   All Other      
                                             Salary       Bonus (1)          Options                Compensation (2) 
 Name and Principal Position      Year         ($)           ($)               (#)                        ($)        
- ---------------------------------------------------------------------------------------------------------------------
 <S>                              <C>        <C>           <C>              <C>                        <C> 
 Alan W. Tuck (3)                 1996       102,062           --           100,000 (3)                287,502 (3)   
 President &                      1995       245,447           --           100,000 (3)                  1,471       
 Chief Executive Officer          1994       240,115           --           100,000 (3)                  1,989       
- ---------------------------------------------------------------------------------------------------------------------
 James D. Grant (4)               1996            --           --           105,000 (4)                     --       
 Chief Executive Officer                                                                                             
- ---------------------------------------------------------------------------------------------------------------------
 Una S. Ryan, Ph.D.               1996       212,347       21,521           100,000 (6)                 48,546 (5)   
 President and Chief              1995       204,996           --            50,000 (6)                  1,155       
 Executive Officer                1994       204,615           --            25,345 (6)                 69,291 (5)   
- ---------------------------------------------------------------------------------------------------------------------
 Duff Brace (6)                   1996       115,559           --                --                        935       
 President & Chief                1995       170,499           --            20,000 (7)                  1,108       
 Operating Officer,               1994       106,615           --           100,000 (7)                104,784 (5)(7)
 T Cell Diagnostics                                                                                                  
- ---------------------------------------------------------------------------------------------------------------------
 Norman W. Gorin                  1996       103,896        8,687           100,000 (8)                     --       
 Vice President, Finance                                                                                             
 and Chief Financial                                                                                                 
 Officer                                                                                                             
- ---------------------------------------------------------------------------------------------------------------------
 James L. Levin                   1996       143,456       10,199                --                      1,471       
 Vice President,                  1995       126,623           --            30,000 (9)                  1,170       
 Research and                     1994       115,749           --            26,357 (9)                  1,016       
 Development                                                                                                         
- ---------------------------------------------------------------------------------------------------------------------
</TABLE>

(1) The bonus amounts in each fiscal year represent payouts under the Company's
    Performance Plan which were accrued for that fiscal year. At the beginning
    of each fiscal year the Compensation Committee sets performance goals to be
    met during the fiscal year and at the end of the year determines the
    percentage of goals achieved upon which bonus payouts are made. See "Report
    of the Compensation Committee of the Board of Directors on Executive
    Compensation." During 1996, the Company achieved certain of the goals
    outlined at the beginning of the year resulting in a payout of one-third of
    the eligible bonus. Payout of the 1996 bonus occurred on February 7, 1997. 
    No payouts were made for the 1994 and 1995 fiscal years.

(2) Includes the Company's matching cash contribution to the 401(k) Savings Plan
    of each named executive officer. Premiums paid for life insurance under the
    Company's nondiscriminatory group plan are not included.

(3) Mr. Tuck was terminated from the positions of President and Chief Executive
    Officer of the Company effective May 28, 1996 and resigned from the Board of
    Directors of the Company on July 10, 1997. In connection with his

                                        6

<PAGE>


    termination, Mr. Tuck and the Company entered into a settlement agreement
    and general release (the "Agreement") which provided for payments to Mr. 
    Tuck amounting to $286,227. In addition to the payments to Mr. Tuck, the
    Agreement provided for the acceleration of all unvested stock options
    outstanding and for the right to exercise such options until July 22, 1997,
    at which time the right to exercise expires. On December 9, 1994, Mr. Tuck
    was granted an option to purchase 50,000 shares at an exercise price of
    $2.75 with vesting in one year and an option to purchase an additional
    50,000 shares at the same price with vesting after five years, with earlier
    vesting upon achievement of a specified performance goal at the end of 1995.
    Mr. Tuck was granted an option on January 1, 1995 to purchase 18,009 shares
    at an exercise price of $2.50 with vesting in one year as part of a special
    incentive grant to the Company's employees, and was granted an option on
    December 8, 1995 to purchase 81,991 shares at an exercise price of $2.938,
    vesting over 4 years. On January 2, 1996, Mr. Tuck was granted an option to
    purchase 100,000 shares of the Company's stock at $3.188 per share, vesting
    over four years.

(4) Mr. Grant assumed the position of Chief Executive Officer, in addition to
    retaining his position as Chairman of the Board of Directors, following the
    termination of Mr. Tuck, effective May 28, 1996. Mr. Grant held the position
    until August 13, 1996 during which time he did not receive cash compensation
    in addition to that which he received as Chairman of the Board of Directors
    and Consultant to the Company. On May 21, 1996, Mr. Grant was granted an
    option to purchase 5,000 shares of common stock at an exercise price of
    $3.00 per share pursuant to the Company's Amended and Restated 1991 Stock
    Compensation Plan and on August 12, 1996, Mr. Grant was granted an option to
    purchase 100,000 shares of common stock at an exercise price of $2.50 per
    share. Effective August 13, 1996, Dr. Ryan was named to the position of
    Chief Executive Officer in addition to her position as President of the
    Company.

(5) Amount represents payments made to Dr. Ryan and Mr. Brace, or on their
    behalf, for relocation as part of their employment by the Company.

(6) In connection with her employment, Dr. Ryan was granted an option on March
    31, 1993 to purchase 75,000 shares at an exercise price of $6.125. She was
    granted on December 31, 1993 an option to purchase 15,000 shares at an
    exercise price of $7.8125; on June 30, 1994 an option to purchase 10,000
    shares at an exercise price of $3.5625; and on December 30, 1994 an option
    to purchase 4,000 shares at an exercise price of $2.50, each with vesting
    over four years. She was granted an option on December 30, 1994 to purchase
    11,345 shares at an exercise price of $2.50 with vesting in one year as part
    of a special incentive grant to the Company's employees. On December 8,
    1995, Dr. Ryan was granted an option to purchase 50,000 shares at an
    exercise price of $2.938, vesting over four years. On August 12 , 1996, Dr.
    Ryan was granted an option to purchase 100,000 shares at an exercise price
    of $2.50 per share. Of the 100,000 shares, 65,000 shares vest over four
    years and 25,000 shares vest on May 28, 2001, subject to earlier vesting
    upon achievement of certain specified performance goals. The remaining
    10,000 shares were fully vested on December 31, 1996 due to the achievement
    of certain specified performance goals. All options have a ten year term.

(7) Mr. Brace resigned as President and COO of T Cell Diagnostics, Inc. and as
    Vice President of the Company effective March 1, 1996 in connection with the
    Company's sale of the research products business of T Cell Diagnostics, Inc.
    In connection with his initial employment, Mr. Brace was granted on May 31,
    1994 an option to purchase 60,000 shares at an exercise price of $3.9375
    with vesting over four years and an option to purchase 40,000 shares at the
    same exercise price with vesting after five years, subject to earlier
    vesting beginning in 1995 based on the achievement of certain specified
    quarterly performance goals. Mr. Brace also was granted an option to
    purchase 20,000 shares on January 1, 1995 at an exercise price of $2.50 with
    vesting after five years, subject to earlier vesting beginning in 1996 based
    on the achievement of certain specified quarterly performance goals. All of
    these options have a ten year term; however, due to the termination of Mr.
    Brace's employment, all outstanding options were canceled. Also, in
    connection with his employment, Mr. Brace was given a loan of $90,000 of
    which one-half the amount was forgivable on March 31, 1995 and the remainder
    on March 1, 1996.

(8) In connection with his employment, on May 21, 1996, Mr. Gorin was granted an
    option to purchase 100,000 shares at an exercise price of $3.00 per share.
    Of the 100,000 shares, 65,000 shares vest annually over four years and
    25,000 shares vest on May 21, 2001, subject to earlier vesting upon
    achievement of certain specified performance goals. The remaining 10,000
    shares were fully vested on December 31, 1996 due to the achievement of
    certain specified performance goals. All options have a ten year term.

(9) In connection with his employment, Dr. Levin was granted an option on April
    30, 1992 to purchase 15,000 shares at an exercise price of $6.625. He was
    granted on June 30, 1993 an option to purchase 10,000 shares

                                        7

<PAGE>


    at an exercise price of $6.375; on June 30, 1994 an option to purchase 8,000
    shares at an exercise price of $3.5625; on August 31, 1994 an option to
    purchase 10,000 at an exercise price of $3.5875; and on December 30, 1994 an
    option to purchase 4,000 shares at an exercise price of $2.50, each with
    vesting over four years. He was granted an option on December 30, 1994 to
    purchase 4,357 shares at an exercise price of $2.50 with vesting in one year
    as part of a special incentive grant to the Company's employees. On December
    8, 1995, Dr. Levin was granted an option to purchase 30,000 shares at an
    exercise price of $2.938, vesting over four years. All options have a ten
    year term.


Options Granted in Last Fiscal Year 

     The following table sets forth each grant of stock options made during the
1996 fiscal year to each of the executive officers named in the Summary
Compensation Table above: 


<TABLE>
<CAPTION>
                                                                                           Potential Realizable 
                                                                                             Value at Assumed   
                                                                                              Annual Rates of   
                                                                                            Price Appreciation  
                                    Individual Grants                                         for Option Term   
- ----------------------------------------------------------------------------------------------------------------
                         Number of         Percent of                                                           
                        Securities        Total Options        Exercise                                         
                        Underlying         Granted to          Per Share                                        
                          Options         Employees in          Price      Expiration                         
       Name             Granted (#)      Fiscal Year (1)       ($/Sh)         Date          5% ($)      10% ($)  
- ----------------------------------------------------------------------------------------------------------------
 <S>                       <C>                <C>                <C>         <C>           <C>         <C>      
 Alan Tuck                  52,000            11.9%              3.188       07/22/97        8,289      16,578 
                            48,000            11.0%              3.188       07/22/97        7,651      15,302 
- ----------------------------------------------------------------------------------------------------------------
 James D. Grant            100,000            22.9%              2.500       08/12/06      157,223     398,436 
                             5,000             1.1%              3.000       05/21/06        9,433      23,906 
- ----------------------------------------------------------------------------------------------------------------
 Una S. Ryan, Ph.D.        100,000            22.9%              2.500       08/12/06      157,223     398,436 
- ----------------------------------------------------------------------------------------------------------------
 Norman W. Gorin           100,000            22.9%              3.000       05/21/06      188,668     478,123 
- ----------------------------------------------------------------------------------------------------------------
</TABLE>



(1) During 1996, a total of 437,600 options were granted to the Company's
    employees. The percentages were calculated as if those options granted in
    1996 which were subsequently canceled remained outstanding as of the end of
    the 1996. For a description of each option grant, see "Summary Compensation
    Table," footnote (3) for Mr. Tuck, footnote (4) for Mr. Grant, footnote (6)
    for Dr. Ryan, and footnote (8) for Mr. Gorin.


Aggregated Option Exercises in Last Fiscal Year and Fiscal Year End Option
Values 

     The following table sets forth, for each of the executive officers named in
the Summary Compensation Table above, the shares acquired and the value realized
in each exercise of stock options during the 1996 fiscal year and the fiscal
year end number and value of unexercised options: 

<TABLE>
<CAPTION>
                                                               Number of Securities                 Value of Unexercised     
                            Shares                            Underlying Unexercised                In-the-Money Options     
                           Acquired          Value        Options at Fiscal Year End (#)         at Fiscal Year End (1) ($)  
                              on            Realized     -------------------------------     --------------------------------
        Name              Exercise (#)        ($)        Exercisable      Unexercisable       Exerciseable      Unexercisable
- -----------------------------------------------------------------------------------------------------------------------------
 <S>                          <C>              <C>          <C>              <C>                   <C>               <C>           
 Alan W. Tuck                 --               --           800,000               --               --                --           
- -----------------------------------------------------------------------------------------------------------------------------
 James D. Grant               --               --           105,000           80,000               --                --           
- -----------------------------------------------------------------------------------------------------------------------------
 Una S. Ryan, Ph.D.           --               --           121,423          143,922               --                --           
- -----------------------------------------------------------------------------------------------------------------------------
 Norman W. Gorin              --               --            10,000           90,000               --                --           
- -----------------------------------------------------------------------------------------------------------------------------
 James L. Levin, DVM          --               --            45,357           36,000               --                --          
- -----------------------------------------------------------------------------------------------------------------------------
</TABLE>

(1) Based on the $1.626 per share closing price of the Company's Common Stock on
    December 31, 1996. 

Employment Contracts, Termination of Employment and Change-of-Control
Arrangements

     Dr. Ryan entered into an agreement with the Company on May 28, 1996
providing for an annual base salary of at least $240,000 and under which she is
eligible for a severance payment of one year's base salary, continuation of
health insurance benefits and outplacement services in the event of her
termination for Good Reason or by the 

                                        8

<PAGE>

Company other than for Cause. "Good Reason" generally means a material change in
her authority, responsibilities (or compensation), within one year of a change
of control, which includes the acquisition or merger of a certain percentage of
the Company's stock. "Cause" generally means willful or gross misconduct. 

     Mr. Gorin entered into an agreement with the Company on May 28, 1996 under
which he is eligible for a severance payment of one year's base salary,
continuation of health insurance benefits and outplacement services in the event
of his termination for Good Reason or by the Company other than for Cause. "Good
Reason" generally means a material change in his authority, responsibilities (or
compensation), within one year of a change of control, which includes the
acquisition or merger of a certain percentage of the Company's stock. "Cause"
generally means willful or gross misconduct. 

     Dr. Levin has an agreement with the Company under which he is eligible for
a severance payment of one year's base salary, continuation of health insurance
benefits and 100% vesting of all stock option grants in the event of his
termination following a change of control. "Change of control", as defined in
the Company's Amended and Restated 1991 Stock Compensation Plan, is the
acquisition or merger of a certain percentage of the Company's stock or the
election of a certain percentage of directors not nominated by the Board,
provided the Board of Directors has adopted a resolution that such a change of
control has occurred. 

     Mr. Tuck and the Company entered into a Settlement Agreement and General
Release (the "Agreement") in connection with his termination from the positions
of President and Chief Executive Officer and resignation from the Board of
Directors, effective May 28, 1996. The Agreement provided for payments to Mr.
Tuck amounting to $286,227 and continuation of health and life insurance
benefits until the earlier of November 30, 1997 or the date on which Mr. Tuck
becomes eligible for comparable coverage. In addition to the payments to Mr.
Tuck, the Agreement provided for the acceleration of all unvested stock options
outstanding and for the right to exercise such options until July 22, 1997, at
which time the right to exercise expires. 

Compensation Committee Interlocks and Insider Participation 

     The Compensation Committee of the Board of Directors was composed of two
non-employee directors, Messrs. Thomas Ostermueller and John Simon, during the
year. Neither of these Compensation Committee members has been an officer or
employee of the Company. 

     No Compensation Committee interlocks between the Company and another entity
exist. 

Report of the Compensation Committee of the Board of Directors on Executive
Compensation

     The Compensation Committee of the Board of Directors of the Company (the
"Committee"), which is comprised of non-employee directors, is responsible for
establishing and administering the policies governing the compensation of the
Company's employees, including salary, bonus and stock option grants. The policy
of the Committee is to compensate the Company's employees with competitive
salaries based on their level of experience and job performance. All permanent
employees of the Company, including executive officers, are eligible for annual
bonus awards based on achievement of the Company's strategic corporate goals,
and participation in the Company's stock option program. The bonus awards and
stock option grants are made in accordance with the Company's Performance Plan
and Amended and Restated 1991 Stock Compensation Plan. The Committee is also
responsible for the administration of the Company's 1994 Employee Stock Purchase
Plan, in which employees participate on a voluntary basis. 

     In order to both attract and retain experienced and qualified executives to
manage the Company, the Committee's policy on executive compensation is to (i)
pay salaries which are competitive with the salaries of executives in comparable
positions in the biotechnology industry, and (ii) allow for additional
compensation upon achievement of corporate goals under the bonus Performance
Plan and through stock price appreciation of shares vested to them from stock
options granted at fair market value. This policy is designed to have a
significant portion of each executive's total compensation be at risk based upon
the Company's progress in order to incentivize the executive to fully dedicate
himself or herself to achievement of corporate goals, and to align the
executive's interest with those of the Company's stockholders through equity
incentive compensation. 

     Each executive officer (except the Chief Executive Officer whose
performance is reviewed by the Committee) has an annual formal performance
review with the Chief Executive Officer who then makes recommendations on 

                                        9

<PAGE>

salary increases, promotions and stock option grants to the Compensation
Committee. The recommended salary increases are based on the average salary
increases expected in the biotechnology industry in the Boston, Massachusetts
area, with the salaries in 1996 either at or slightly above the average of the
salaries paid to persons in comparable positions using an independently prepared
1996 employee compensation survey of approximately 292 biotechnology companies.
Due to financial constraints within the Company, no salary increases for
executive officers were made at the end of 1996. 

     The bonus award is based on the percentage of achievement of the Company's
strategic goals which are set at the beginning of each fiscal year and measured
against performance at the end of the year by the Committee in accordance with
the Company's Performance Plan. For 1996, two sets of goals were applicable to
all employees, including the executive officers: One set of overall corporate
goals and a second set of goals applicable to the therapeutic programs. Both
sets of goals were allocated between specific product and financial performance
targets. The Compensation Committee determined that the Company achieved certain
of the stated goals and that one-third of the eligible cash payout would be made
under the plan for 1996. In 1996, the stock option awards for the executive
officers other than the Chief Executive Officer consisted of grants made as part
of either commitments made at hiring or in conjunction with a review of the
executives' performance during the year. The Compensation Committee believes the
number of underlying shares are consistent with the stock option grant practices
of other companies in the biotechnology industry. 

     Dr. Una Ryan, the Company's President and Chief Executive Officer, received
a salary increase of approximately 12% effective May 28, 1996. The salary
increase was made in connection with her appointment to the position of
President and Chief Operating Officer and subsequent appointment to Chief
Executive Officer of the Company. Dr. Ryan's annualized base salary, reflecting
the salary increase, was within the range of base salaries paid to other Chief
Executive Officers in similar sized companies in the biotechnology industry,
based on the previously referenced 1996 employee compensation survey. Dr. Ryan
received no salary increase for 1997. As discussed above, the Compensation
Committee determined that a cash payout would be made under the performance plan
for 1996 for which Dr. Ryan received one-third of her eligible bonus of 30% of
base salary. 

     On August 12, 1996, Dr. Ryan was granted an option to purchase 100,000
shares of Common Stock at an exercise price of $2.50 per share. Of the 100,000
shares underlying the option, 65,000 shares vest equally over four years; 25,000
shares vest on May 28, 2001, subject to earlier vesting upon achievement of
certain specified performance goals; and 10,000 shares vest equally over four
years, subject to earlier vesting upon achievement of certain specified
performance goals. These 10,000 shares were fully vested on December 31, 1996
due to the achievement of the specified goals. 

                                          Compensation Committee 

                                          THOMAS OSTERMUELLER, Chairman
                                          JOHN SIMON 

                                       10

<PAGE>


Stock Performance Graph 

     The graph below represents a comparison of the cumulative shareholder
return on the Common Stock for the Company's last five fiscal years, including
the fiscal year ended December 31, 1996, with the cumulative total stockholder
return of the Nasdaq Stock Market (U.S.) Index and Nasdaq Pharmaceutical Stock
Index (which is made up of companies quoted on the Nasdaq National Market whose
Primary Industrial Classification Code is 283, Pharmaceutical Companies). The
graph assumes an investment of $100 on April 30, 1992 in the Company's Common
Stock and in the two indexes. 


[TABULAR REPRESENTATION OF LINE CHART]

<TABLE>
<CAPTION>
                                       4/30/92     12/31/92       12/31/93     12/30/94       12/29/95      12/31/96 
                                       -------     --------       --------     --------       --------      -------- 
<S>                                      <C>          <C>           <C>           <C>            <C>           <C>   
T Cell Sciences, Inc.                    $100         $107          $113           $36            $45           $24  
Nasdaq Stock Market (U.S.) Index         $100         $118          $135          $132           $187          $230  
Nasdaq Pharmaceutical Stock Index        $100         $115          $102          $ 77           $141          $141  
</TABLE>

                             INDEPENDENT ACCOUNTANTS

     On February 10, 1994, the Board of Directors of the Company approved the
engagement of the firm Price Waterhouse LLP as its independent accountants.
Price Waterhouse replaced KPMG Peat Marwick LLP effective February 10, 1994. The
Company expects that a representative from Price Waterhouse will be present at
the Annual Meeting to make a statement if they desire to do so and to respond to
appropriate questions. 

     In connection with the audits of the Company's financial statements in the
period of the fiscal year which ended December 31, 1994 prior to the termination
of the engagement of KPMG Peat Marwick, there were no disagreements with KPMG
Peat Marwick on any matter of accounting principles or practices, financial
statement disclosure or auditing scope or procedure which, if not resolved to
the satisfaction of KPMG Peat Marwick, would have caused KPMG Peat Marwick to
make reference to the matter in connection with its reports on the Company's
financial statements with respect to such periods. Also, in the interim period
prior to the engagement of Price Waterhouse, there were no "reportable events"
as defined in subparagraph (a)(1)(v) of Item 304 of Commission Regulation S-K.
Neither the Company nor anyone else on its behalf consulted Price Waterhouse
regarding either (i) application of accounting principles to a specified
transaction, either completed or proposed or (ii) the type of audit opinion that
might be rendered on the Company's financial statements. 


                                       11

<PAGE>

                  STOCKHOLDER PROPOSALS FOR 1998 ANNUAL MEETING

     Stockholder proposals intended to be presented at the Company's 1998 Annual
Meeting of Stockholders must be received by the Company no later than April 26,
1998 and no earlier than January 13, 1998 in order to be considered for
inclusion in the Company's proxy statement and form of proxy for that meeting.
The Company's By-Laws provide that any stockholder of record wishing to have a
stockholder proposal considered at an annual meeting (other than a stockholder
proposal included in the Company's proxy statement as described above) must
provide written notice of such proposal and appropriate supporting
documentation, as set forth in the By-Laws, to the Company at its principal
executive office not less than 75 days or more than 120 days prior to the first
anniversary of the date of the preceding year's annual meeting. In the event,
however, that the annual meeting is scheduled to be held more than 30 days
before such anniversary date or more than 60 days after such anniversary date,
notice must also be delivered on the later of (i) the 15th day after the date of
public announcement of the date of such meeting or (ii) the 75th day of the
scheduled date of such meeting. Any such proposal should be mailed to:
Secretary, T Cell Sciences, Inc., 119 Fourth Avenue, Needham, MA 02194. 

                                 OTHER BUSINESS

     The Board of Directors knows of no other business to be acted upon at the
meeting. However, if any other business properly comes before the meeting, it is
the intention of persons named in the enclosed proxy to vote on such matters in
accordance with their best judgment. 

     The prompt return of the proxy will be appreciated and helpful in obtaining
the necessary vote. Therefore, whether or not you expect to attend the meeting,
please sign the proxy and return it in the enclosed envelope. 

                                          By order of the Board of Directors 


                                          NORMAN W. GORIN
                                          Secretary 

Dated: April 15, 1997 

A COPY OF THE COMPANY'S ANNUAL REPORT ON FORM 10-K WILL BE SENT WITHOUT CHARGE
TO ANY STOCKHOLDER REQUESTING IT IN WRITING FROM T CELL SCIENCES, INC.,
ATTENTION: INVESTOR RELATIONS, 119 FOURTH AVENUE, NEEDHAM, MASSACHUSETTS 02194. 



                                       12


<PAGE>
                             T CELL SCIENCES, INC.

               Proxy Solicited by the Board of Directors for the
                         Annual Meeting of Stockholders
                                on May 13, 1997

The undersigned hereby appoints James D. Grant, Patrick C. Kung and Una S. Ryan,
and each of them, as the true and lawful attorneys, agents and proxies of the
undersigned, with full power of substitution, and hereby authorizes them to
represent and to vote, as designated on the reverse, all shares of Common Stock
held of record by the undersigned on April 1, 1997, at the Annual Meeting of
Stockholders (the "Meeting") to be held at 2:00 p.m. on May 13, 1997 at State
Street Bank and Trust Company, 225 Franklin Street, Boston, Massachusetts 02110,
or at any adjournment or postponement thereof. When properly executed, this
proxy will be voted in the manner directed herein by the undersigned
stockholder(s). If no direction is given, this proxy will be voted FOR the
election of the nominees for director listed in Proposal 1 and, in their
discretion, the proxies are each authorized to vote upon such other business as
may properly come before the Meeting and any adjournments or postponements
thereof. Any stockholders wishing to vote in accordance with the Board of
Directors' recommendations need only sign and date this proxy and return it in
the postage paid envelope provided.


- ------------------ PLEASE VOTE, DATE AND SIGN ON REVERSE AND--------------------
                   RETURN PROMPTLY IN THE ENCLOSED ENVELOPE.

Please sign exactly as your name(s) appear(s) on the books of the Corporation.
Joint owners are to each sign personally, Trustees and other fiduciaries are to
indicate the capacity in which they sign, and where more than one name appears,
a majority must sign. If a corporation, the signature must be that of an
authorized officer who should state his or her title.

- --------------------------------------------------------------------------------

HAS YOUR ADDRESS CHANGED?                    DO YOU HAVE ANY COMMENTS?

____________________________________         _________________________________

____________________________________         _________________________________

____________________________________         _________________________________



<PAGE>
[x]  PLEASE MARK VOTES 
     AS IN THIS EXAMPLE

     ----------------------        
     T CELL SCIENCES, INC.         
     ----------------------        

     1.   Election of Directors.

               James D. Grant, Patrick C. Kung,                          FOR ALL
          John P. Munson, Thomas R. Osturmueller,    FOR    WITHHELD    EXCEPT
        Harry H. Penner, Jr., Una S. Ryan, John Simon  [ ]      [ ]       [ ]

     NOTE: If you do not wish your shares voted "For" a particular nominee, 
     mark the "For ALL Except" box and strike a line through the nominee's(s')
     name(s). Your shares will be voted for the remaining nominee(s).

RECORD DATE SHARES:




Please be sure to sign and date this Proxy.       Date:


                              Mark box at right if an address change 
                              or comment has been noted on the reverse     [ ]
                              side of this card.


______________________        _________________
Stockholder sign here         Co-owner sign here




DETACH CARD                                                      DETACH CARD

                             T CELL SCIENCES, INC.

Dear Stockholder:

Please take note of the important information enclosed with this Proxy Ballot.

Your vote counts, and you are strongly encouraged to exercise your right to vote
your shares.

Please mark the boxes on this proxy card to indicate how your shares will be
voted. Then sign the card, detach it and return your proxy vote in the enclosed
postage paid envelope.

Your vote must be received prior to the Annual Meeting of Stockholders, May 13,
1997.

Thank you in advance for your prompt consideration of these matters.


Sincerely,


T Cell Sciences, Inc.











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