WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000746382
<NAME> PRUDENTIAL MUNICIPAL SERIES FUND:
<SERIES>
<NUMBER> 001
<NAME> CONNECTICUT MONEY MARKET SERIES
<S> <C>
<PERIOD-TYPE> YEAR
<FISCAL-YEAR-END> AUG-31-2000
<PERIOD-END> AUG-31-2000
<INVESTMENTS-AT-COST> 81,045,038
<INVESTMENTS-AT-VALUE> 81,045,038
<RECEIVABLES> 964,066
<ASSETS-OTHER> 36,089
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 0
<PAYABLE-FOR-SECURITIES> 678,140
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 142,400
<TOTAL-LIABILITIES> 0
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 81,224,653
<SHARES-COMMON-STOCK> 81,224,653
<SHARES-COMMON-PRIOR> 83,403,565
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> (164,628,218)
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 3,049,551
<OTHER-INCOME> 0
<EXPENSES-NET> 670,689
<NET-INVESTMENT-INCOME> 2,378,862
<REALIZED-GAINS-CURRENT> (94)
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 2,378,768
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 0
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 283,076,236
<NUMBER-OF-SHARES-REDEEMED> (287,264,699)
<SHARES-REINVESTED> 2,336,383
<NET-CHANGE-IN-ASSETS> 526,688
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 410,257
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 666,393
<AVERAGE-NET-ASSETS> 82,051,000
<PER-SHARE-NAV-BEGIN> 1.00
<PER-SHARE-NII> 0.03
<PER-SHARE-GAIN-APPREC> (0.03)
<PER-SHARE-DIVIDEND> 0.00
<PER-SHARE-DISTRIBUTIONS> 0.00
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 1.00
<EXPENSE-RATIO> 0.82
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] FLORIDA SERIES (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 92,909,045
[INVESTMENTS-AT-VALUE] 95,792,092
[RECEIVABLES] 2,799,648
[ASSETS-OTHER] 31,199
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 297,340
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 830,484
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 95,539,284
[SHARES-COMMON-STOCK] 9,533,527
[SHARES-COMMON-PRIOR] 9,978,818
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (955,996)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,911,827
[NET-ASSETS] (19,512,345)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 6,065,696
[OTHER-INCOME] 0
[EXPENSES-NET] 1,066,776
[NET-INVESTMENT-INCOME] 4,998,920
[REALIZED-GAINS-CURRENT] (854,986)
[APPREC-INCREASE-CURRENT] 1,063,077
[NET-CHANGE-FROM-OPS] 5,207,011
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (4,998,920)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 11,228,470
[NUMBER-OF-SHARES-REDEEMED] (25,414,666)
[SHARES-REINVESTED] 2,239,613
[NET-CHANGE-IN-ASSETS] (11,738,492)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (825,733)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 502,329
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,066,140
[AVERAGE-NET-ASSETS] 71,083,000
[PER-SHARE-NAV-BEGIN] 10.18
[PER-SHARE-NII] 0.51
[PER-SHARE-GAIN-APPREC] 0.05
[PER-SHARE-DIVIDEND] (0.51)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.23
[EXPENSE-RATIO] 0.98
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 002
[NAME] FLORIDA SERIES (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 92,909,045
[INVESTMENTS-AT-VALUE] 95,792,092
[RECEIVABLES] 2,799,648
[ASSETS-OTHER] 31,199
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 297,340
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 830,484
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 95,539,284
[SHARES-COMMON-STOCK] 9,533,527
[SHARES-COMMON-PRIOR] 9,978,818
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (955,996)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,911,827
[NET-ASSETS] (19,512,345)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 6,065,696
[OTHER-INCOME] 0
[EXPENSES-NET] 1,066,776
[NET-INVESTMENT-INCOME] 4,998,920
[REALIZED-GAINS-CURRENT] (854,986)
[APPREC-INCREASE-CURRENT] 1,063,077
[NET-CHANGE-FROM-OPS] 5,207,011
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (4,998,920)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 11,228,470
[NUMBER-OF-SHARES-REDEEMED] (25,414,666)
[SHARES-REINVESTED] 2,239,613
[NET-CHANGE-IN-ASSETS] (11,738,492)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (825,733)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 502,329
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,066,140
[AVERAGE-NET-ASSETS] 23,191,000
[PER-SHARE-NAV-BEGIN] 10.18
[PER-SHARE-NII] 0.48
[PER-SHARE-GAIN-APPREC] 0.05
[PER-SHARE-DIVIDEND] (0.48)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.23
[EXPENSE-RATIO] 1.23
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] FLORIDA SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 92,909,045
[INVESTMENTS-AT-VALUE] 95,792,092
[RECEIVABLES] 2,799,648
[ASSETS-OTHER] 31,199
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 297,340
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 830,484
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 95,539,284
[SHARES-COMMON-STOCK] 9,533,527
[SHARES-COMMON-PRIOR] 9,978,818
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (955,996)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,911,827
[NET-ASSETS] (19,512,345)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 6,065,696
[OTHER-INCOME] 0
[EXPENSES-NET] 1,066,776
[NET-INVESTMENT-INCOME] 4,998,920
[REALIZED-GAINS-CURRENT] (854,986)
[APPREC-INCREASE-CURRENT] 1,063,077
[NET-CHANGE-FROM-OPS] 5,207,011
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (4,998,920)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 11,228,470
[NUMBER-OF-SHARES-REDEEMED] (25,414,666)
[SHARES-REINVESTED] 2,239,613
[NET-CHANGE-IN-ASSETS] (11,738,492)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (825,733)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 502,329
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,066,140
[AVERAGE-NET-ASSETS] 5,885,000
[PER-SHARE-NAV-BEGIN] 10.18
[PER-SHARE-NII] 0.46
[PER-SHARE-GAIN-APPREC] 0.05
[PER-SHARE-DIVIDEND] (0.46)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.23
[EXPENSE-RATIO] 1.48
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 004
[NAME] FLORIDA SERIES (CLASS Z)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 92909045
[INVESTMENTS-AT-VALUE] 95792092
[RECEIVABLES] 2799648
[ASSETS-OTHER] 31199
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 297340
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 830484
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 95539284
[SHARES-COMMON-STOCK] 9533527
[SHARES-COMMON-PRIOR] 9978818
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] -955996
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2911827
[NET-ASSETS] -19512345
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 6065696
[OTHER-INCOME] 0
[EXPENSES-NET] 1066776
[NET-INVESTMENT-INCOME] 4998920
[REALIZED-GAINS-CURRENT] -854986
[APPREC-INCREASE-CURRENT] 1063077
[NET-CHANGE-FROM-OPS] 5207011
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] -4998920
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 11228470
[NUMBER-OF-SHARES-REDEEMED] -25414666
[SHARES-REINVESTED] 2239613
[NET-CHANGE-IN-ASSETS] -11738492
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] -825733
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 502329
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1066140
[AVERAGE-NET-ASSETS] 307,000
[PER-SHARE-NAV-BEGIN] 10.17
[PER-SHARE-NII] 0.53
[PER-SHARE-GAIN-APPREC] 0.05
[PER-SHARE-DIVIDEND] -0.53
[PER-SHARE-DISTRIBUTIONS] 0
[RETURNS-OF-CAPITAL] 0
[PER-SHARE-NAV-END] 9.85
[EXPENSE-RATIO] 0.73
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] MASSACHUSETTS SERIES (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 33,657,650
[INVESTMENTS-AT-VALUE] 35,497,991
[RECEIVABLES] 461,669
[ASSETS-OTHER] 57,792
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 0
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 247,141
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 34,383,889
[SHARES-COMMON-STOCK] 3,231,071
[SHARES-COMMON-PRIOR] 3,417,900
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (453,919)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,840,341
[NET-ASSETS] (6,648,971)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,277,530
[OTHER-INCOME] 0
[EXPENSES-NET] 499,150
[NET-INVESTMENT-INCOME] 1,778,380
[REALIZED-GAINS-CURRENT] (255,485)
[APPREC-INCREASE-CURRENT] 69,319
[NET-CHANGE-FROM-OPS] 1,592,214
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,778,380)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 1,277,060
[NUMBER-OF-SHARES-REDEEMED] (7,028,093)
[SHARES-REINVESTED] 991,084
[NET-CHANGE-IN-ASSETS] (4,946,115)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (198,434)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 185,314
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 498,811
[AVERAGE-NET-ASSETS] 26,551,000
[PER-SHARE-NAV-BEGIN] 11.09
[PER-SHARE-NII] 0.53
[PER-SHARE-GAIN-APPREC] (0.02)
[PER-SHARE-DIVIDEND] (0.53)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.07
[EXPENSE-RATIO] 1.28
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 002
[NAME] MASSACHUSETTS SERIES (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 33,657,650
[INVESTMENTS-AT-VALUE] 35,497,991
[RECEIVABLES] 461,669
[ASSETS-OTHER] 57,792
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 0
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 247,141
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 34,383,889
[SHARES-COMMON-STOCK] 3,231,071
[SHARES-COMMON-PRIOR] 3,417,900
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (453,919)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,840,341
[NET-ASSETS] (6,648,971)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,277,530
[OTHER-INCOME] 0
[EXPENSES-NET] 499,150
[NET-INVESTMENT-INCOME] 1,778,380
[REALIZED-GAINS-CURRENT] (255,485)
[APPREC-INCREASE-CURRENT] 69,319
[NET-CHANGE-FROM-OPS] 1,592,214
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,778,380)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 1,277,060
[NUMBER-OF-SHARES-REDEEMED] (7,028,093)
[SHARES-REINVESTED] 991,084
[NET-CHANGE-IN-ASSETS] (4,946,115)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (198,434)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 185,314
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 498,811
[AVERAGE-NET-ASSETS] 10,214,000
[PER-SHARE-NAV-BEGIN] 11.08
[PER-SHARE-NII] 0.50
[PER-SHARE-GAIN-APPREC] (0.01)
[PER-SHARE-DIVIDEND] (0.50)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.07
[EXPENSE-RATIO] 1.52
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] MASSACHUSETTS SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 33,657,650
[INVESTMENTS-AT-VALUE] 35,497,991
[RECEIVABLES] 461,669
[ASSETS-OTHER] 57,792
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 0
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 247,141
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 34,383,889
[SHARES-COMMON-STOCK] 3,231,071
[SHARES-COMMON-PRIOR] 3,417,900
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (453,919)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,840,341
[NET-ASSETS] (6,648,971)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,277,530
[OTHER-INCOME] 0
[EXPENSES-NET] 499,150
[NET-INVESTMENT-INCOME] 1,778,380
[REALIZED-GAINS-CURRENT] (255,485)
[APPREC-INCREASE-CURRENT] 69,319
[NET-CHANGE-FROM-OPS] 1,592,214
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,778,380)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 1,277,060
[NUMBER-OF-SHARES-REDEEMED] (7,028,093)
[SHARES-REINVESTED] 991,084
[NET-CHANGE-IN-ASSETS] (4,946,115)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (198,434)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 185,314
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 498,811
[AVERAGE-NET-ASSETS] 220,000
[PER-SHARE-NAV-BEGIN] 11.08
[PER-SHARE-NII] 0.48
[PER-SHARE-GAIN-APPREC] (0.01)
[PER-SHARE-DIVIDEND] (0.48)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.07
[EXPENSE-RATIO] 1.76
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] MASSACHUSETTS SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 33,657,650
[INVESTMENTS-AT-VALUE] 35,497,991
[RECEIVABLES] 461,669
[ASSETS-OTHER] 57,792
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 0
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 247,141
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 34,383,889
[SHARES-COMMON-STOCK] 3,231,071
[SHARES-COMMON-PRIOR] 3,417,900
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (453,919)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,840,341
[NET-ASSETS] (6,648,971)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,277,530
[OTHER-INCOME] 0
[EXPENSES-NET] 499,150
[NET-INVESTMENT-INCOME] 1,778,380
[REALIZED-GAINS-CURRENT] (255,485)
[APPREC-INCREASE-CURRENT] 69,319
[NET-CHANGE-FROM-OPS] 1,592,214
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,778,380)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 1,277,060
[NUMBER-OF-SHARES-REDEEMED] (7,028,093)
[SHARES-REINVESTED] 991,084
[NET-CHANGE-IN-ASSETS] (4,946,115)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (198,434)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 185,314
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 498,811
[AVERAGE-NET-ASSETS] 220,000
[PER-SHARE-NAV-BEGIN] 11.08
[PER-SHARE-NII] 0.48
[PER-SHARE-GAIN-APPREC] (0.01)
[PER-SHARE-DIVIDEND] (0.48)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.07
[EXPENSE-RATIO] 1.76
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] MASSACHUSETTS MONEY MARKET SERIES
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 87,991,037
[INVESTMENTS-AT-VALUE] 87,991,037
[RECEIVABLES] 3,055,166
[ASSETS-OTHER] 63,617
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 0
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 2,741,595
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 88,368,225
[SHARES-COMMON-STOCK] 88,368,225
[SHARES-COMMON-PRIOR] 67,615,069
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] 0
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 0
[NET-ASSETS] (155,983,294)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,643,490
[OTHER-INCOME] 0
[EXPENSES-NET] 571,439
[NET-INVESTMENT-INCOME] 2,072,051
[REALIZED-GAINS-CURRENT] 0
[APPREC-INCREASE-CURRENT] 0
[NET-CHANGE-FROM-OPS] 2,072,051
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] 0
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 224,336,862
[NUMBER-OF-SHARES-REDEEMED] (193,500,915)
[SHARES-REINVESTED] 2,028,747
[NET-CHANGE-IN-ASSETS] 34,936,745
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 0
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 339,393
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 571,077
[AVERAGE-NET-ASSETS] 67,879,000
[PER-SHARE-NAV-BEGIN] 1.00
[PER-SHARE-NII] 0.03
[PER-SHARE-GAIN-APPREC] 0.00
[PER-SHARE-DIVIDEND] (0.03)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 1.00
[EXPENSE-RATIO] 0.84
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] MUNI - NORTH CAROLINA
[SERIES]
[NUMBER] 001
[NAME] MUNI - NORTH CAROLINA (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 37,330,475
[INVESTMENTS-AT-VALUE] 39,048,910
[RECEIVABLES] 1,074,887
[ASSETS-OTHER] 36,567
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 63,259
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 111,614
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 38,731,689
[SHARES-COMMON-STOCK] 3,637,903
[SHARES-COMMON-PRIOR] 3,763,801
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (464,633)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,718,435
[NET-ASSETS] (7,401,704)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,451,879
[OTHER-INCOME] 0
[EXPENSES-NET] 505,517
[NET-INVESTMENT-INCOME] 1,946,362
[REALIZED-GAINS-CURRENT] (463,196)
[APPREC-INCREASE-CURRENT] 572,593
[NET-CHANGE-FROM-OPS] 2,055,759
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,946,362)
[DISTRIBUTIONS-OF-GAINS] (19,647)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 971,027
[NUMBER-OF-SHARES-REDEEMED] (8,068,943)
[SHARES-REINVESTED] 1,005,340
[NET-CHANGE-IN-ASSETS] (6,002,826)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (507,900)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 205,793
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 505,245
[AVERAGE-NET-ASSETS] 28,635,000
[PER-SHARE-NAV-BEGIN] 10.92
[PER-SHARE-NII] 0.52
[PER-SHARE-GAIN-APPREC] 0.08
[PER-SHARE-DIVIDEND] (0.52)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] (0.01)
[PER-SHARE-NAV-END] 10.99
[EXPENSE-RATIO] 1.15
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] MUNI - NORTH CAROLINA
[SERIES]
[NUMBER] 002
[NAME] MUNI - NORTH CAROLINA (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 37,330,475
[INVESTMENTS-AT-VALUE] 39,048,910
[RECEIVABLES] 1,074,887
[ASSETS-OTHER] 36,567
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 63,259
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 111,614
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 38,731,689
[SHARES-COMMON-STOCK] 3,637,903
[SHARES-COMMON-PRIOR] 3,763,801
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (464,633)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,718,435
[NET-ASSETS] (7,401,704)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,451,879
[OTHER-INCOME] 0
[EXPENSES-NET] 505,517
[NET-INVESTMENT-INCOME] 1,946,362
[REALIZED-GAINS-CURRENT] (463,196)
[APPREC-INCREASE-CURRENT] 572,593
[NET-CHANGE-FROM-OPS] 2,055,759
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,946,362)
[DISTRIBUTIONS-OF-GAINS] (19,647)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 971,027
[NUMBER-OF-SHARES-REDEEMED] (8,068,943)
[SHARES-REINVESTED] 1,005,340
[NET-CHANGE-IN-ASSETS] (6,002,826)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (507,900)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 205,793
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 505,245
[AVERAGE-NET-ASSETS] 12,495,000
[PER-SHARE-NAV-BEGIN] 10.93
[PER-SHARE-NII] 0.49
[PER-SHARE-GAIN-APPREC] 0.07
[PER-SHARE-DIVIDEND] (0.49)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] (0.01)
[PER-SHARE-NAV-END] 10.99
[EXPENSE-RATIO] 1.39
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] MUNI - NORTH CAROLINA
[SERIES]
[NUMBER] 003
[NAME] MUNI - NORTH CAROLINA (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 37,330,475
[INVESTMENTS-AT-VALUE] 39,048,910
[RECEIVABLES] 1,074,887
[ASSETS-OTHER] 36,567
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 63,259
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 111,614
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 38,731,689
[SHARES-COMMON-STOCK] 3,637,903
[SHARES-COMMON-PRIOR] 3,763,801
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (464,633)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 1,718,435
[NET-ASSETS] (7,401,704)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 2,451,879
[OTHER-INCOME] 0
[EXPENSES-NET] 505,517
[NET-INVESTMENT-INCOME] 1,946,362
[REALIZED-GAINS-CURRENT] (463,196)
[APPREC-INCREASE-CURRENT] 572,593
[NET-CHANGE-FROM-OPS] 2,055,759
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (1,946,362)
[DISTRIBUTIONS-OF-GAINS] (19,647)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 971,027
[NUMBER-OF-SHARES-REDEEMED] (8,068,943)
[SHARES-REINVESTED] 1,005,340
[NET-CHANGE-IN-ASSETS] (6,002,826)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (507,900)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 205,793
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 505,245
[AVERAGE-NET-ASSETS] 29,000
[PER-SHARE-NAV-BEGIN] 10.93
[PER-SHARE-NII] 0.47
[PER-SHARE-GAIN-APPREC] 0.07
[PER-SHARE-DIVIDEND] (0.47)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] (0.01)
[PER-SHARE-NAV-END] 10.99
[EXPENSE-RATIO] 1.64
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] NEW JERSEY SERIES (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 168,066,061
[INVESTMENTS-AT-VALUE] 173,522,374
[RECEIVABLES] 2,401,801
[ASSETS-OTHER] 36,558
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 502,594
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 303,612
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 169,886,969
[SHARES-COMMON-STOCK] 16,440,784
[SHARES-COMMON-PRIOR] 18,051,835
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (188,755)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 5,456,313
[NET-ASSETS] (34,492,619)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,931,727
[OTHER-INCOME] 0
[EXPENSES-NET] 1,882,803
[NET-INVESTMENT-INCOME] 9,048,924
[REALIZED-GAINS-CURRENT] (179,142)
[APPREC-INCREASE-CURRENT] (52,835)
[NET-CHANGE-FROM-OPS] 8,816,947
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,048,924)
[DISTRIBUTIONS-OF-GAINS] (901,505)
[DISTRIBUTIONS-OTHER] (4,726)
[NUMBER-OF-SHARES-SOLD] 9,732,263
[NUMBER-OF-SHARES-REDEEMED] (44,474,004)
[SHARES-REINVESTED] 5,857,005
[NET-CHANGE-IN-ASSETS] (30,022,944)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 891,892
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 931,841
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,879,547
[AVERAGE-NET-ASSETS] 122,573,000
[PER-SHARE-NAV-BEGIN] 10.67
[PER-SHARE-NII] 0.52
[PER-SHARE-GAIN-APPREC] 0.03
[PER-SHARE-DIVIDEND] (0.52)
[PER-SHARE-DISTRIBUTIONS] (0.05)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.65
[EXPENSE-RATIO] 0.92
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 002
[NAME] NEW JERSEY SERIES (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 168,066,061
[INVESTMENTS-AT-VALUE] 173,522,374
[RECEIVABLES] 2,401,801
[ASSETS-OTHER] 36,558
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 502,594
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 303,612
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 169,886,969
[SHARES-COMMON-STOCK] 16,440,784
[SHARES-COMMON-PRIOR] 18,051,835
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (188,755)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 5,456,313
[NET-ASSETS] (34,492,619)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,931,727
[OTHER-INCOME] 0
[EXPENSES-NET] 1,882,803
[NET-INVESTMENT-INCOME] 9,048,924
[REALIZED-GAINS-CURRENT] (179,142)
[APPREC-INCREASE-CURRENT] (52,835)
[NET-CHANGE-FROM-OPS] 8,816,947
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,048,924)
[DISTRIBUTIONS-OF-GAINS] (901,505)
[DISTRIBUTIONS-OTHER] (4,726)
[NUMBER-OF-SHARES-SOLD] 9,732,263
[NUMBER-OF-SHARES-REDEEMED] (44,474,004)
[SHARES-REINVESTED] 5,857,005
[NET-CHANGE-IN-ASSETS] (30,022,944)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 891,892
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 931,841
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,879,547
[AVERAGE-NET-ASSETS] 61,647,000
[PER-SHARE-NAV-BEGIN] 10.67
[PER-SHARE-NII] 0.49
[PER-SHARE-GAIN-APPREC] 0.04
[PER-SHARE-DIVIDEND] (0.49)
[PER-SHARE-DISTRIBUTIONS] (0.05)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.66
[EXPENSE-RATIO] 1.17
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] NEW JERSEY SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 168,066,061
[INVESTMENTS-AT-VALUE] 173,522,374
[RECEIVABLES] 2,401,801
[ASSETS-OTHER] 36,558
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 502,594
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 303,612
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 169,886,969
[SHARES-COMMON-STOCK] 16,440,784
[SHARES-COMMON-PRIOR] 18,051,835
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (188,755)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 5,456,313
[NET-ASSETS] (34,492,619)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,931,727
[OTHER-INCOME] 0
[EXPENSES-NET] 1,882,803
[NET-INVESTMENT-INCOME] 9,048,924
[REALIZED-GAINS-CURRENT] (179,142)
[APPREC-INCREASE-CURRENT] (52,835)
[NET-CHANGE-FROM-OPS] 8,816,947
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,048,924)
[DISTRIBUTIONS-OF-GAINS] (901,505)
[DISTRIBUTIONS-OTHER] (4,726)
[NUMBER-OF-SHARES-SOLD] 9,732,263
[NUMBER-OF-SHARES-REDEEMED] (44,474,004)
[SHARES-REINVESTED] 5,857,005
[NET-CHANGE-IN-ASSETS] (30,022,944)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 891,892
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 931,841
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,879,547
[AVERAGE-NET-ASSETS] 2,077,000
[PER-SHARE-NAV-BEGIN] 10.67
[PER-SHARE-NII] 0.47
[PER-SHARE-GAIN-APPREC] 0.04
[PER-SHARE-DIVIDEND] (0.47)
[PER-SHARE-DISTRIBUTIONS] (0.05)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.66
[EXPENSE-RATIO] 1.42
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 004
[NAME] NEW JERSEY SERIES (CLASS Z)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 168066061
[INVESTMENTS-AT-VALUE] 173522374
[RECEIVABLES] 2401801
[ASSETS-OTHER] 36558
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 502594
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 303612
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 169886969
[SHARES-COMMON-STOCK] 16440784
[SHARES-COMMON-PRIOR] 18051835
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] -188755
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 5456313
[NET-ASSETS] -34492619
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10931727
[OTHER-INCOME] 0
[EXPENSES-NET] 1882803
[NET-INVESTMENT-INCOME] 9048924
[REALIZED-GAINS-CURRENT] -179142
[APPREC-INCREASE-CURRENT] -52835
[NET-CHANGE-FROM-OPS] 8816947
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] -9048924
[DISTRIBUTIONS-OF-GAINS] -901505
[DISTRIBUTIONS-OTHER] -4726
[NUMBER-OF-SHARES-SOLD] 9732263
[NUMBER-OF-SHARES-REDEEMED] -44474004
[SHARES-REINVESTED] 5857005
[NET-CHANGE-IN-ASSETS] -30022944
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 891892
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 931841
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1879547
[AVERAGE-NET-ASSETS] 198
[PER-SHARE-NAV-BEGIN] 10.75
[PER-SHARE-NII] 0.55
[PER-SHARE-GAIN-APPREC] 0.03
[PER-SHARE-DIVIDEND] -0.55
[PER-SHARE-DISTRIBUTIONS] -0.05
[RETURNS-OF-CAPITAL] 0
[PER-SHARE-NAV-END] 10.73
[EXPENSE-RATIO] 0.67
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0
<**AMOUNTS ARE ACTUAL AND NOT ROUNDED TO THE NEAREST THOUSAND.>
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] NEW YORK MONEY MARKET SERIES
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 363,258,426
[INVESTMENTS-AT-VALUE] 363,258,426
[RECEIVABLES] 7,511,531
[ASSETS-OTHER] 82,119
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 8,601,533
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 375,797
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 361,874,746
[SHARES-COMMON-STOCK] 361,874,746
[SHARES-COMMON-PRIOR] 385,852,214
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] 0
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 0
[NET-ASSETS] (747,726,960)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 14,199,375
[OTHER-INCOME] 0
[EXPENSES-NET] 2,566,942
[NET-INVESTMENT-INCOME] 11,632,433
[REALIZED-GAINS-CURRENT] 0
[APPREC-INCREASE-CURRENT] 0
[NET-CHANGE-FROM-OPS] 11,632,433
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (11,632,433)
[DISTRIBUTIONS-OF-GAINS] 0
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 1,308,822,886
[NUMBER-OF-SHARES-REDEEMED] (1,316,846,351)
[SHARES-REINVESTED] 11,342,243
[NET-CHANGE-IN-ASSETS] 3,318,778
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] 0
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 1,845,085
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 2,559,444
[AVERAGE-NET-ASSETS] 369,017,000
[PER-SHARE-NAV-BEGIN] 1.00
[PER-SHARE-NII] 0.03
[PER-SHARE-GAIN-APPREC] 0.00
[PER-SHARE-DIVIDEND] (0.03)
[PER-SHARE-DISTRIBUTIONS] 0.00
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 1.00
[EXPENSE-RATIO] 0.70
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] OHIO SERIES (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 57,988,566
[INVESTMENTS-AT-VALUE] 60,564,961
[RECEIVABLES] 706,111
[ASSETS-OTHER] 100,084
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 622,274
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 155,330
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 58,138,264
[SHARES-COMMON-STOCK] 5,371,731
[SHARES-COMMON-PRIOR] 5,939,038
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (121,107)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,576,395
[NET-ASSETS] (11,310,769)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 3,948,930
[OTHER-INCOME] 0
[EXPENSES-NET] 790,853
[NET-INVESTMENT-INCOME] 3,158,077
[REALIZED-GAINS-CURRENT] (12,628)
[APPREC-INCREASE-CURRENT] (165,452)
[NET-CHANGE-FROM-OPS] 2,979,997
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (3,158,077)
[DISTRIBUTIONS-OF-GAINS] (378,204)
[DISTRIBUTIONS-OTHER] (31,000)
[NUMBER-OF-SHARES-SOLD] 1,352,379
[NUMBER-OF-SHARES-REDEEMED] (15,195,098)
[SHARES-REINVESTED] 2,139,011
[NET-CHANGE-IN-ASSETS] (12,290,992)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (174,527)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 329,819
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 789,482
[AVERAGE-NET-ASSETS] 45,671,000
[PER-SHARE-NAV-BEGIN] 11.33
[PER-SHARE-NII] 0.54
[PER-SHARE-GAIN-APPREC] 0.02
[PER-SHARE-DIVIDEND] (0.54)
[PER-SHARE-DISTRIBUTIONS] (0.07)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.28
[EXPENSE-RATIO] 1.12
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 002
[NAME] OHIO SERIES (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 57,988,566
[INVESTMENTS-AT-VALUE] 60,564,961
[RECEIVABLES] 706,111
[ASSETS-OTHER] 100,084
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 622,274
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 155,330
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 58,138,264
[SHARES-COMMON-STOCK] 5,371,731
[SHARES-COMMON-PRIOR] 5,939,038
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (121,107)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,576,395
[NET-ASSETS] (11,310,769)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 3,948,930
[OTHER-INCOME] 0
[EXPENSES-NET] 790,853
[NET-INVESTMENT-INCOME] 3,158,077
[REALIZED-GAINS-CURRENT] (12,628)
[APPREC-INCREASE-CURRENT] (165,452)
[NET-CHANGE-FROM-OPS] 2,979,997
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (3,158,077)
[DISTRIBUTIONS-OF-GAINS] (378,204)
[DISTRIBUTIONS-OTHER] (31,000)
[NUMBER-OF-SHARES-SOLD] 1,352,379
[NUMBER-OF-SHARES-REDEEMED] (15,195,098)
[SHARES-REINVESTED] 2,139,011
[NET-CHANGE-IN-ASSETS] (12,290,992)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (174,527)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 329,819
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 789,482
[AVERAGE-NET-ASSETS] 20,094,000
[PER-SHARE-NAV-BEGIN] 11.34
[PER-SHARE-NII] 0.51
[PER-SHARE-GAIN-APPREC] 0.02
[PER-SHARE-DIVIDEND] (0.51)
[PER-SHARE-DISTRIBUTIONS] (0.07)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.29
[EXPENSE-RATIO] 1.36
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] OHIO SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 57,988,566
[INVESTMENTS-AT-VALUE] 60,564,961
[RECEIVABLES] 706,111
[ASSETS-OTHER] 100,084
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 622,274
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 155,330
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 58,138,264
[SHARES-COMMON-STOCK] 5,371,731
[SHARES-COMMON-PRIOR] 5,939,038
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (121,107)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 2,576,395
[NET-ASSETS] (11,310,769)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 3,948,930
[OTHER-INCOME] 0
[EXPENSES-NET] 790,853
[NET-INVESTMENT-INCOME] 3,158,077
[REALIZED-GAINS-CURRENT] (12,628)
[APPREC-INCREASE-CURRENT] (165,452)
[NET-CHANGE-FROM-OPS] 2,979,997
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (3,158,077)
[DISTRIBUTIONS-OF-GAINS] (378,204)
[DISTRIBUTIONS-OTHER] (31,000)
[NUMBER-OF-SHARES-SOLD] 1,352,379
[NUMBER-OF-SHARES-REDEEMED] (15,195,098)
[SHARES-REINVESTED] 2,139,011
[NET-CHANGE-IN-ASSETS] (12,290,992)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (174,527)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 329,819
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 789,482
[AVERAGE-NET-ASSETS] 198,000
[PER-SHARE-NAV-BEGIN] 11.34
[PER-SHARE-NII] 0.48
[PER-SHARE-GAIN-APPREC] 0.02
[PER-SHARE-DIVIDEND] (0.48)
[PER-SHARE-DISTRIBUTIONS] (0.07)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 11.29
[EXPENSE-RATIO] 1.61
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 001
[NAME] PENNSYLVANIA SERIES (CLASS A)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 159,773,326
[INVESTMENTS-AT-VALUE] 163,136,361
[RECEIVABLES] 2,343,264
[ASSETS-OTHER] 74,056
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 1,052,790
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 287,816
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 161,204,613
[SHARES-COMMON-STOCK] 16,334,494
[SHARES-COMMON-PRIOR] 17,788,253
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (397,742)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 3,406,204
[NET-ASSETS] (34,122,747)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,885,210
[OTHER-INCOME] 0
[EXPENSES-NET] 1,757,189
[NET-INVESTMENT-INCOME] 9,128,021
[REALIZED-GAINS-CURRENT] (346,914)
[APPREC-INCREASE-CURRENT] (1,287,612)
[NET-CHANGE-FROM-OPS] 7,493,495
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,128,021)
[DISTRIBUTIONS-OF-GAINS] (586,935)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 5,600,166
[NUMBER-OF-SHARES-REDEEMED] (38,181,577)
[SHARES-REINVESTED] 5,405,137
[NET-CHANGE-IN-ASSETS] (29,397,735)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (805,023)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 875,729
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,749,740
[AVERAGE-NET-ASSETS] 106,181,000
[PER-SHARE-NAV-BEGIN] 10.13
[PER-SHARE-NII] 0.53
[PER-SHARE-GAIN-APPREC] (0.05)
[PER-SHARE-DIVIDEND] (0.53)
[PER-SHARE-DISTRIBUTIONS] (0.03)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.05
[EXPENSE-RATIO] 0.90
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 002
[NAME] PENNSYLVANIA SERIES (CLASS B)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 159,773,326
[INVESTMENTS-AT-VALUE] 163,136,361
[RECEIVABLES] 2,343,264
[ASSETS-OTHER] 74,056
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 1,052,790
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 287,816
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 161,204,613
[SHARES-COMMON-STOCK] 16,334,494
[SHARES-COMMON-PRIOR] 17,788,253
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (397,742)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 3,406,204
[NET-ASSETS] (34,122,747)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,885,210
[OTHER-INCOME] 0
[EXPENSES-NET] 1,757,189
[NET-INVESTMENT-INCOME] 9,128,021
[REALIZED-GAINS-CURRENT] (346,914)
[APPREC-INCREASE-CURRENT] (1,287,612)
[NET-CHANGE-FROM-OPS] 7,493,495
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,128,021)
[DISTRIBUTIONS-OF-GAINS] (586,935)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 5,600,166
[NUMBER-OF-SHARES-REDEEMED] (38,181,577)
[SHARES-REINVESTED] 5,405,137
[NET-CHANGE-IN-ASSETS] (29,397,735)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (805,023)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 875,729
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,749,740
[AVERAGE-NET-ASSETS] 68,309,000
[PER-SHARE-NAV-BEGIN] 10.13
[PER-SHARE-NII] 0.50
[PER-SHARE-GAIN-APPREC] (0.05)
[PER-SHARE-DIVIDEND] (0.50)
[PER-SHARE-DISTRIBUTIONS] (0.03)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.05
[EXPENSE-RATIO] 1.15
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
[ARTICLE] 6
[CIK] 0000746382
[NAME] PRUDENTIAL MUNICIPAL SERIES FUND:
[SERIES]
[NUMBER] 003
[NAME] PENNSYLVANIA SERIES (CLASS C)
<S> <C>
[PERIOD-TYPE] YEAR
[FISCAL-YEAR-END] AUG-31-2000
[PERIOD-END] AUG-31-2000
[INVESTMENTS-AT-COST] 159,773,326
[INVESTMENTS-AT-VALUE] 163,136,361
[RECEIVABLES] 2,343,264
[ASSETS-OTHER] 74,056
[OTHER-ITEMS-ASSETS] 0
[TOTAL-ASSETS] 0
[PAYABLE-FOR-SECURITIES] 1,052,790
[SENIOR-LONG-TERM-DEBT] 0
[OTHER-ITEMS-LIABILITIES] 287,816
[TOTAL-LIABILITIES] 0
[SENIOR-EQUITY] 0
[PAID-IN-CAPITAL-COMMON] 161,204,613
[SHARES-COMMON-STOCK] 16,334,494
[SHARES-COMMON-PRIOR] 17,788,253
[ACCUMULATED-NII-CURRENT] 0
[OVERDISTRIBUTION-NII] 0
[ACCUMULATED-NET-GAINS] (397,742)
[OVERDISTRIBUTION-GAINS] 0
[ACCUM-APPREC-OR-DEPREC] 3,406,204
[NET-ASSETS] (34,122,747)
[DIVIDEND-INCOME] 0
[INTEREST-INCOME] 10,885,210
[OTHER-INCOME] 0
[EXPENSES-NET] 1,757,189
[NET-INVESTMENT-INCOME] 9,128,021
[REALIZED-GAINS-CURRENT] (346,914)
[APPREC-INCREASE-CURRENT] (1,287,612)
[NET-CHANGE-FROM-OPS] 7,493,495
[EQUALIZATION] 0
[DISTRIBUTIONS-OF-INCOME] (9,128,021)
[DISTRIBUTIONS-OF-GAINS] (586,935)
[DISTRIBUTIONS-OTHER] 0
[NUMBER-OF-SHARES-SOLD] 5,600,166
[NUMBER-OF-SHARES-REDEEMED] (38,181,577)
[SHARES-REINVESTED] 5,405,137
[NET-CHANGE-IN-ASSETS] (29,397,735)
[ACCUMULATED-NII-PRIOR] 0
[ACCUMULATED-GAINS-PRIOR] (805,023)
[OVERDISTRIB-NII-PRIOR] 0
[OVERDIST-NET-GAINS-PRIOR] 0
[GROSS-ADVISORY-FEES] 875,729
[INTEREST-EXPENSE] 0
[GROSS-EXPENSE] 1,749,740
[AVERAGE-NET-ASSETS] 655,000
[PER-SHARE-NAV-BEGIN] 10.13
[PER-SHARE-NII] 0.48
[PER-SHARE-GAIN-APPREC] (0.05)
[PER-SHARE-DIVIDEND] (0.48)
[PER-SHARE-DISTRIBUTIONS] (0.03)
[RETURNS-OF-CAPITAL] 0.00
[PER-SHARE-NAV-END] 10.05
[EXPENSE-RATIO] 1.40
[AVG-DEBT-OUTSTANDING] 0
[AVG-DEBT-PER-SHARE] 0.00
</TABLE>
