ADVANCED VIRAL RESEARCH CORP
8-K, 1997-03-04
PHARMACEUTICAL PREPARATIONS
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                                                                     Page 1 of 4

                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549

                                    FORM 8-K

                                 CURRENT REPORT


                       PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934


    Date of Report (Date of earliest event reported) - February 21, 1997


                          ADVANCED VIRAL RESEARCH CORP.
             (Exact name of registrant as specified in its charter)


    DELAWARE                         33-2262-A                59-2646820
(State or other juris-           (Commission File           (IRS Employer
diction of incorporation)             Number)            Identification No.)


                  1250 East Hallandale Beach Blvd.
                  Suite 501
                  HALLANDALE, FLORIDA                         33009
                  (Address or principal executive offices        (zip code)


          Registrant's telephone number, including area code:  (954) 458-7636




                                      NONE
           (Former name or former address, if changed since last report)


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<PAGE>


                                                                  Page 2 of 4

ITEM 1.           CHANGES IN CONTROL OF REGISTRANT

                  Not Applicable

ITEM 2.           ACQUISITION OR DISPOSITION OF ASSETS

                  Not Applicable

ITEM 3.           BANKRUPTCY OR RECEIVERSHIP

                  Not Applicable

ITEM 4.           CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT

                  Not Applicable

ITEM 5.           OTHER EVENTS

                  A. _______ On February 21, 1997 Advanced  Viral Research Corp.
                  ("ADVR")  sold  $1,000,000  face  amount  of its  ten-year  7%
                  Convertible  Debenture  to RBB Bank AG ("RBB") in an  offshore
                  transaction  pursuant to Regulation S under the Securities Act
                  of 1933.  The Debenture is  convertible  into common shares of
                  the Company pursuant to a formula more particularly  described
                  in the  Debenture,  a copy of  which  is  attached  hereto  as
                  Exhibit 3. In connection with the aforesaid  transaction,  the
                  Company  issued to RBB three  Warrants to purchase  its common
                  stock,  each such  Warrant  entitling  the holder to  purchase
                  178,378  shares of the Company's  common  stock.  The exercise
                  prices of the three Warrants are $0.288, $0.576 and $0.864 per
                  Warrant   share,    respectively.    Each   Warrant   contains
                  anti-dilution  provisions  which provide for the adjustment of
                  Warrant  price and  Warrant  shares as more  particularly  set
                  forth  therein.  A copy of the first of the three  Warrants is
                  attached  hereto as Exhibit 4 with the second and third  being
                  identical in all respects except as set forth above.

                  B.  _______ On  February  24,  1997 the  Company  received  an
                  executed  lease  dated  February  7, 1997 from  Robert  Martin
                  Company,   LLC,  as  landlord,  to  the  Company,  as  tenant,
                  concerning  approximately  6,100 square feet of rentable space
                  at 200 Corporate Boulevard South,  Yonkers, New York. The term
                  of the  lease is five  years  at a base  rent of  $85,400  per
                  annum.  The Company  intends to use the demised  premises as a
                  general office and laboratory and for medical research.

                  C.  _______ On  February  24, 1997  Robert C.  Kolodny,  M.D.,
                  accepted the Company's  invitation to serve as a member of its
                  Board  of   Directors   until  the  next  annual   meeting  of
                  shareholders  and until a successor shall be elected and shall
                  qualify.

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<PAGE>


                                                                    Page 3 of 4

                  A copy of Dr. Kolodny's  professional and business  experience
                  is attached hereto as Exhibit 5.


ITEM 6.           RESIGNATION OF REGISTRANT'S DIRECTORS

                  Not Applicable

ITEM 7.           FINANCIAL STATEMENTS AND EXHIBITS

                  (a)      Financial statements of business acquired

                           None

                  (b)      Pro forma financial information

                           None

                  (c)      Exhibits

        (1)      ______ Copy of Purchase  and Sale  agreement
                 dated  February 21, 1997 between the Company
                 and RBB Bank AG.

        (2)      Copy of Agency Agreement dated December 16, 1996 between the
                 Company and Interfi Capital Group.

        (3)      The Company's 7% Convertible Debenture

        (4)      The Company's Warrant to Purchase Common Stock

        (5)      Curriculum Vitae of Robert C. Kolodny, M.D.

ITEM 8.           CHANGE IN FISCAL YEAR

                  Not Applicable



                      [This Space Intentionally Left Blank]

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<PAGE>


                                                                    Page 4 of 4


                                   SIGNATURES

                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.


                                              ADVANCED VIRAL RESEARCH CORP.
                                              (Registrant)


                                              By: /S/ WILLIAM BREGMAN
                                                       William Bregman,
                                                       Secretary-Treasurer


Date:  February 27, 1997


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<PAGE>




                                LIST OF EXHIBITS

(1)     Copy of Purchase and Sale Agreement dated February 21, 1997 between the
        Company and RBB Bank AG

(2)     Copy of Agency Agreement dated December 16, 1996 between the Company and
        Interfi Capital Group Inc.

(3)     The Company's 7% Convertible Debenture

(4)     The Company's Warrant to Purchase Common Stock

(5)     Curriculum Vitae of Robert C. Kolodny, M.D.

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<PAGE>

EXHIBIT 1                                                     February 21, 1997


Agreement  dated this 21st day of February,  1997 by and between  ADVANCED VIRAL
RESEARCH  CORP., a Delaware  corporation  (the  "Company"),  with offices at 200
Corporate  Boulevard,  Yonkers,  New York 10701 and RBB Bank  Aktiengesellschaft
(the "Purchaser" or "you") with offices at Burgring 16, 8010 Graz, Austria.


                                    ARTICLE I

                         AUTHORIZATION OF THE SECURITIES

                  The Company  represents that it has taken all corporate action
necessary to authorize the issuance and sale of (a) its 7% Convertible Debenture
due February 28, 2007 in the principal  amount of $1,000,000  (the  "Debenture")
and (b) warrants to purchase an aggregate of 535,134 shares of Common Stock, par
value $.00001 per share ("Common Stock"),  of the Company (the "Warrants").  The
Debenture  and the  Warrants  (collectively,  the  "Securities")  are to be sold
pursuant to this  Agreement to you.  Interest on the Debenture is payable at the
rate of 7% per annum,  as more  particularly  specified in the form of Debenture
attached  hereto as Exhibit A. The  Debenture is  convertible  from time to time
into shares of Common Stock as provided therein.  For purposes of this Agreement
the term "Shares" shall mean the shares of Common Stock which may be issued upon
conversion of all or a portion of the principal  amount of the Debenture and the
shares of Common  Stock  that may be issued  from time to time  pursuant  to the
exercise of the Warrants.


                                   ARTICLE II

                  SALE AND PURCHASE OF THE SECURITIES; CLOSING

                  2.1. _____ SALE AND PURCHASE OF THE SECURITIES. Subject to the
terms  and  conditions  hereof  and  in  reliance  on  the  representations  and
warranties contained herein, or made pursuant hereto, the Company will issue and
sell  to the  Purchaser  for  its  own  account  and  for  the  accounts  of its
participants  as more  particularly  referred to below,  and the Purchaser  will
purchase  from the Company,  on the Closing  Date  specified in Section 2.2, the
Securities for the aggregate purchase price contemplated hereby.

                   2.2. CLOSING. (a) The closing of the purchase and sale of the
Securities (the "Closing") shall be deemed to occur when this Agreement has been
executed  by both the  Company and the  Purchaser  and the Company has  received
payment for the Securities. Such date is herein called the "Closing Date."


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<PAGE>



                  (b) ______ On the Closing  Date there will be delivered to the
Purchaser (i) a Debenture  dated the Closing  Date, in the principal  amount set
forth opposite the Purchaser's  name on Exhibit B and (ii) warrant  certificates
in the forms of Exhibits  D-1, D-2 and D-3  registered in the  Purchaser's  name
representing  the right to  purchase  the  number of shares of Common  Stock set
forth opposite the Purchaser's name on Exhibit B. The foregoing Securities shall
be delivered by the Company, against delivery by the Purchaser to the Company of
an  unendorsed  certified or official  bank check drawn upon or issued by a bank
which is a member of the New York Clearinghouse for banks (or wire transfer) for
$1,000,000 payable to the order of the Company.


                                   ARTICLE III

                 REPRESENTATIONS AND WARRANTIES OF THE PURCHASER

                  3.1. _____ OFFSHORE TRANSACTION.  The Purchaser represents and
warrants to the Company that (a) the  Purchaser  is not a "U.S.  person" as that
term is defined in Rule 902(o) of Regulation S promulgated  by the United States
Securities and Exchange  Commission (the "Commission")  under the Securities Act
of  1933,  as  amended  (the  "Securities  Act");  (b) the  Purchaser  is not an
affiliate  of the  Company;  (c) at the  time of  execution  of this  Agreement,
Purchaser was outside the United States and no offer to purchase the  Securities
was made in the United  States;  (d) the  Purchaser  agrees  that all offers and
sales of the Securities  prior to the  expiration of a period  commencing on the
Closing Date and ending forty (40) days  thereafter  (the  "Restricted  Period")
shall not be made to U.S.  persons or for the account or benefit of U.S. persons
and shall  otherwise be made in compliance  with the provisions of Regulation S;
(e)  the  Purchaser  is  not a  distributor  or  dealer;  (f)  the  transactions
contemplated  hereby  (i) have not  been  and  will not be  pre-arranged  by the
Purchaser with a purchaser  located in the United States or a purchaser which is
a U.S. Person,  and (ii) are not and will not be part of a plan or scheme by the
Purchaser to evade the  registration  provisions of the Securities  Act; (g) the
Purchaser  shall  take  all  reasonable  steps to  ensure  its  compliance  with
Regulation  S and  shall  promptly  send to  each  purchaser  (x) who  acts as a
distributor,  underwriter,  dealer or other person  participating  pursuant to a
contractual  arrangement  in the  distribution  of the Securities or receiving a
selling  concession,  fee  or  other  remuneration  in  respect  of  any  of the
Securities,  or (y) who  purchases  prior to the  expiration  of the  Restricted
Period,  a  confirmation  or other  notice  to the  purchaser  stating  that the
purchaser  is  subject  to the same  restrictions  on  offers  and  sales as the
Purchaser pursuant to Section 903(c)(2)(iv) of Regulation S; and (h) none of the
Purchaser,  its  affiliates or persons acting on their behalf have conducted and
shall not conduct any "directed selling efforts" as that term is defined in Rule
902(b) of Regulation S; nor has the Purchaser,  its affiliates or persons acting
on their behalf conducted any general  solicitation to the offer and sale of any
of the Securities in the United States or elsewhere.

                   3.2.  BENEFICIAL  OWNER.  The  Purchaser  is  purchasing  the
Securities for its own account or for the account of beneficiaries  with respect
to the  Securities  and whom the Purchaser  has full  authority to bind, so that

28877_4
                                                         2

<PAGE>



each  such  beneficiary  is bound  hereby as if such  beneficiary  were a direct
purchaser  hereunder and all  representations,  warranties and agreements herein
were made  directly by such  beneficiary.  Neither the Purchaser nor any of such
beneficiaries own, or upon completion of this transaction, or upon conversion of
all or any part of the Debentures,  will beneficially own, more than 4.5% of the
Common Stock of the Company.

                  3.3. _____ DIRECTED  SELLING  EFFORTS.  The Purchaser will not
engage in any activity for the purpose of, or that could  reasonably be expected
to have the effect of,  conditioning  the market in the United States for any of
the Securities sold hereunder.  To the best knowledge of the Purchaser,  neither
the Company nor any person  acting for the Company has  conducted  any "directed
selling efforts" as that term is defined in Rule 902 of Regulation S.

                   3.4.  SHORT  POSITION.  Neither the  Purchaser nor any of its
affiliates  will  directly  or  indirectly  maintain  any short  position in any
securities of the Company until after the end of the Restricted Period.

                  3.5.  _____  INDEPENDENT   INVESTIGATION.   The  Purchaser  in
electing  to  purchase  the  Securities  hereunder,  has relied  solely upon the
representations and warranties of the Company set forth in this Agreement and on
independent  investigation made by it and its  representatives,  if any, and the
Purchaser has been given no oral or written  representations  or assurance  from
the Company or any representation of the Company other than as set forth in this
Agreement or in a document  executed by a duly authorized  representative of the
Company making reference to this Agreement.

                  Prior to the commencement of the negotiations  concerning this
transaction,  the Purchaser had been a shareholder of the Company. In connection
therewith the Purchaser had conducted  such due diligence  investigations  as it
deemed prudent in connection with its investment decision.

                   3.6. NO GOVERNMENT  RECOMMENDATION OR APPROVAL. The Purchaser
understands that no United States federal or state agency,  or similar agency of
any other country,  has passed upon or made any recommendation or endorsement of
the Company, this transaction or the purchase of the Securities.

                   3.7. FURTHER  LIMITATIONS ON DISPOSITION.  Without in any way
limiting the  representations  set forth above, the Purchaser further agrees not
to make any  disposition  of all or any portion of the Securities (or the Common
Stock issuable upon the conversion or exercise thereof) unless and until:

                            (a) There is then in effect a Registration Statement
under the Securities Act covering such proposed disposition and such disposition
is made in accordance with such  Registration  Statement,  or the disposition is
made in compliance with Regulation S; or

                            (b) (1) The Purchaser,  through RBB Bank, shall have
notified the Company of the proposed  disposition  and shall have  furnished the

28877_4
                                                         3

<PAGE>



Company with a statement that it does not  beneficially  own more than 5% of the
Common  Stock of the Company and is not an officer or director of the Company or
(2) if,  the  Purchaser  shall have  furnished  the  Company  with an opinion of
counsel,  reasonably satisfactory to the Company, that such disposition will not
require registration of such Securities under the Securities Act.

                   3.8. LEGAL REPRESENTATION.  The Purchaser has the opportunity
to be represented in this  transaction by counsel of its own choice and has been
so advised by counsel for the Company.


                                   ARTICLE IV

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

                  Other than as provided in the Schedule of Exceptions  attached
hereto as Exhibit C, the Company represents and warrants to you as follows:

                  4.1. _____  ORGANIZATION AND EXISTENCE,  ETC. The Company is a
corporation  duly organized and validly  existing and in good standing under the
laws of its jurisdiction of incorporation, and has all requisite corporate power
and  authority  to carry on its  business as now  conducted  and  proposed to be
conducted;  the Company has all requisite corporate power and authority to enter
into this Agreement, to issue the Securities as contemplated herein and to carry
out  and  perform  its  obligations  under  the  terms  and  conditions  of this
Agreement.  The  Company  does not own or lease  any  property  or engage in any
activity in any jurisdiction which might require qualification to do business as
a foreign  corporation in such  jurisdiction and where the failure to so qualify
would have a material  adverse effect on the financial  condition of the Company
or subject  the Company to a material  liability.  To the extent the Company has
not  qualified  to do  business  in such  jurisdictions,  it has, as of the date
hereof,  prepared the necessary  applications  or documents to be filed with the
appropriate authorities in such jurisdictions to obtain such qualifications. The
Company  has  furnished  you with  true,  correct  and  complete  copies  of its
Certificate of Incorporation, By-laws and all amendments thereto to date.

                   4.2. SUBSIDIARIES AND AFFILIATES.  Except as set forth in the
Schedule of Exceptions,  the Company has no subsidiaries  and does not, and upon
the Closing will not, own of record or beneficially  any capital stock or equity
interest or investment in any corporation, association or business entity.

                  4.3.     CAPITALIZATION.

(a) As of the date hereof,  the Company's  authorized  capital stock consists of
1,000,000,000  shares of Common  Stock,  par value  $.00001 per share,  of which
267,031,058  are  outstanding,  34,365,733 of which are reserved for issuance to
certain  persons  for  the  purposes  stated  in  the  Schedule  of  Exceptions,
15,000,000  of which have been  reserved for  issuance  upon  conversion  of the
Debenture  and 535,134 of which have been reserved for issuance upon exercise of
the Warrants. As of the date hereof, the Company does not hold any shares of its
capital stock in its treasury.

28877_4
                                                         4

<PAGE>



                   (b) All the issued and outstanding shares of capital stock of
the Company shall, as of the Closing,  (i) have been duly authorized and validly
issued,  (ii) be fully  paid and  nonassessable,  and (iii)  have been  offered,
issued,  sold and delivered by the Company in compliance with applicable federal
and state securities laws. Other than as set forth in Section 4.3(a),  there are
no outstanding preemptive, conversion or other rights, options, warrants, calls,
agreements or commitments granted or issued by or binding upon the Company,  for
the purchase or acquisition of any shares of its capital stock.

                   4.4.  AUTHORIZATION.  All corporate action on the part of the
Company and the  directors  and  stockholders  of the Company  necessary for the
authorization,  execution,  delivery  and  performance  by the  Company  of this
Agreement and the transactions  contemplated  herein, and for the authorization,
issuance and delivery of the Securities,  has been taken or will have been taken
prior to the Closing.

                   4.5. BINDING OBLIGATIONS; NO MATERIAL ADVERSE CONTRACTS, ETC.
This Agreement is a valid and binding  obligation of the Company  enforceable in
accordance  with its terms.  The  execution,  delivery  and  performance  by the
Company  of this  Agreement  and  compliance  herewith  will not  result  in any
violation  of and will not  conflict  with,  or result in a breach of any of the
terms of, or constitute a default  under,  any provision of state or Federal law
to which the Company is subject,  the Certificate of Incorporation,  as amended,
or the  By-laws,  as  amended,  of the  Company,  or  any  mortgage,  indenture,
agreement,  instrument,  judgment,  decree,  order,  rule or regulation or other
restriction to which the Company is a party or by which it is bound,  or, result
in the creation of any mortgage, pledge, lien, encumbrance or charge upon any of
the properties or assets of the Company pursuant to any such term. Except as set
forth  herein no  stockholder  of the  Company  has or will have any  preemptive
rights or rights of first refusal by reason of the issuance of the Securities.

                   4.6. FINANCIAL INFORMATION.  The Company has delivered to the
Purchaser true and complete copies of the financial  information  concerning the
Company  identified  in the Schedule of  Exceptions.  Except as may be indicated
thereon,  all  financial  statements  included in the  information  given to the
Purchaser fairly present the financial position and results of operations of the
Company  as at their  respective  dates  and for  their  respective  periods  in
conformity with generally accepted accounting  principles  consistently  applied
throughout the periods covered thereby. As of their respective dates the Company
had no liabilities or obligations of any nature (absolute,  accrued,  contingent
or otherwise) which would normally be reflected on a balance sheet and which are
not reflected on any balance sheet contained in the financial  information given
to the Purchaser or disclosed in accordance  with  generally  accepted  auditing
standards.

                   4.7. COMPLIANCE WITH INSTRUMENTS, ETC. The Company is not (a)
in default past any grace, notice or cure period under any indenture,  agreement

28877_4
                                                         5

<PAGE>



or instrument  to which it is a party or by which it is bound,  (b) in violation
of its  Certificate of  Incorporation,  By-laws or of any applicable law, (c) in
default  with  respect to any order,  writ,  injunction  or decree of any court,
administrative agency or arbitrator, or (d) in default under any order, license,
regulation or demand of any government agency,  which default or violation would
materially and adversely affect the business,  properties,  condition (financial
or otherwise) or business prospects of the Company.

                   4.8.  LITIGATION.  Except  as set  forth in the  Schedule  of
Exceptions, there is no action, suit or proceeding pending, or, to the knowledge
of the Company, threatened, against the Company before any court, administrative
agency or  arbitrator  or any action,  suit or  proceeding  pending,  or, to the
knowledge  of the  Company,  threatened,  which  challenges  the validity of any
action taken or to be taken pursuant to or in connection  with this Agreement or
the issuance of the Securities.

                   4.9.  OFFERING.  Subject in part to the truth and accuracy of
the  Purchaser's  representations  and the  compliance by the Purchaser with its
covenants  set forth in this  Agreement,  the offer,  sale and  issuance  of the
Securities as contemplated by this Agreement are not subject to the registration
requirements of the Securities Act of 1933, as amended (the  "Securities  Act"),
and the  Company,  or anyone  acting  on its  behalf,  will not take any  action
hereafter that would cause such registration requirements to be applicable.

                  4.10. PERMITS;  GOVERNMENTAL AND OTHER APPROVALS.  The Company
possesses  such  franchises,  licenses,  permits  and  other  authority  as  are
necessary for the conduct of its business as now being conducted and proposed to
be conducted by the Company and the Company is not in default  under any of such
franchises,   licenses,  permits  or  other  authority.  No  approval,  consent,
authorization  or other  order of,  and no  designation,  filing,  registration,
qualification or recording with, any governmental  authority or any other person
or entity is required in connection with the Company's valid execution, delivery
and  performance  of this  Agreement  or the  offer,  issuance  and  sale of the
Securities  by the Company to the  Purchaser  or the  consummation  of any other
transaction contemplated on the part of the Company hereby.

                  4.11.  REPORTING  COMPANY STATUS.  The Company is a "Reporting
Issuer"  as  defined  by Rule 902 of  Regulation  S. The  Company  has filed all
material  required  to be filed  pursuant  to all  reporting  obligations  under
Section 15(d) of the Securities Exchange Act of 1934, as amended for a period of
at least  twelve  (12)  months  immediately  preceding  the offer or sale of the
Securities.

                   4.12.  OFFSHORE  TRANSACTION.  The Company has not offered or
sold  the  Securities  to any  person  in the  United  States,  or,  to the best
knowledge of the Company,  any identifiable  groups of U.S.  citizens abroad, or
any U.S.  person as that term is  defined in  Regulation  S. At the time the buy
order of the Securities was originated the Company and/or its agents  reasonably
believed Purchaser was outside the United States and was not a U.S. Person.


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                                                         6

<PAGE>



                   4.13. PREARRANGED SALE. The Company and/or its agents believe
that the transaction  contemplated hereby has not been pre-arranged with a buyer
in the United States.

                   4.14. NO  DIRECTED  SELLING  EFFORTS.  The  Company  has not
conducted any "directed  selling efforts" as that term is defined in Rule 902 of
Regulation S nor has Company conducted any general solicitation  relating to the
offer and sale of the Securities to persons resident within the United States or
any other U.S. person as that term is defined in Rule 902 of Regulation S.

                   4.15. COPYRIGHTS,  TRADEMARKS AND PATENTS.  Set forth in the
Schedule of Exceptions is a list of all the copyrights,  trademark registrations
and patents and applications therefor owned by the Company.

                   4.16. NO RELATIONSHIP  BETWEEN PARTIES. The Company is not an
owner of any  shares of the stock of or equity  interest  in the  Purchaser.  No
officer,  director  or owner of any  shares of the stock of the  Company  or its
subsidiaries  or his close  relatives  is an officer or  director of or owns any
shares of the stock of or equity interest in the Purchaser.

                   4.17. OTHER MATERIAL CONTRACTS.  Set forth in the Schedule of
Exceptions is a list of contracts  material to the  operations of the Company to
which reference is not made elsewhere in this Article IV.

                  4.18.  DISCLOSURE.  The information heretofore provided and to
be provided  pursuant to this  Agreement,  including the Schedules of Exceptions
and the Exhibits hereto, and each of the agreements, documents, certificates and
writings previously  delivered to the Purchaser or its  representatives,  do not
and will not contain any untrue statement of a material fact and do not and will
not omit to state a material  fact  required  to be stated  herein or therein or
necessary  in order to make the  statements  and writings  contained  herein and
therein not false or  misleading in the light of the  circumstances  under which
they  were  made.  To the  knowledge  of the  Company,  there  is no fact  which
materially adversely affects the business,  prospects or condition (financial or
otherwise) of the Company which has not been set forth herein.


                                    ARTICLE V

                     CONDITIONS TO CLOSING OF THE PURCHASER

                  The  obligation of the Purchaser to purchase the Securities at
the Closing is subject to the fulfillment to the Purchaser's  satisfaction on or
prior to the Closing Date of each of the following conditions,  any of which may
be waived by the Purchaser:

                   5.1.  REPRESENTATIONS   AND   WARRANTIES    CORRECT.      The
representations and warranties in Article IV hereof shall be true and correct in

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                                                         7

<PAGE>



all material  respects when made,  and shall be true and correct in all material
respects on the Closing  Date with the same force and effect as if they had been
made on and as of the Closing Date.

                   5.2.  PERFORMANCE.  All covenants,  agreements and conditions
contained in this  Agreement to be performed or complied  with by the Company on
or prior to the Closing Date shall have been  performed or complied  with by the
Company in all material respects.

                   5.3. NO  IMPEDIMENTS.  Neither the Company nor the  Purchaser
shall be subject to any order, decree or injunction of a court or administrative
agency of competent  jurisdiction which would impose any material  limitation on
the  ability of the  Purchaser  to  exercise  full  rights of  ownership  of the
Securities.

                   5.4. OTHER  AGREEMENTS.  The Company shall have issued to the
Purchaser all of the Securities (including the Warrants in the forms of Exhibits
D-1, D-2 and D-3 attached hereto).

                   5.5.  LEGAL  INVESTMENT.  At the  time  of the  Closing,  the
purchase of the Securities to be purchased by the Purchaser  hereunder  shall be
legally  permitted by all laws and  regulations  to which the  Purchaser and the
Company are subject.

                   5.6. DUE DILIGENCE  INVESTIGATION.  The  Purchaser  shall not
have  discovered  any  fact,  whether  or  not  reflected  in  the  Schedule  of
Exceptions,  which in the Purchaser's  determination would make the consummation
of the  transactions  contemplated by this Agreement not in the Purchaser's best
interests.

                   5.7. PROCEEDINGS AND OTHER DOCUMENTS. All corporate and other
proceedings in connection with the  transactions  contemplated by this Agreement
shall  have  been  taken  and the  Purchaser  shall  have  received  such  other
documents,  in form and substance  reasonably  satisfactory to the Purchaser and
the Purchaser's  counsel,  as to such other matters  incident to the transaction
contemplated hereby as the Purchaser may reasonably request.


                                   ARTICLE VI

                      CONDITIONS TO CLOSING OF THE COMPANY

                  The Company's obligation to sell the Securities at the Closing
is subject to the  fulfillment  to its  satisfaction  on or prior to the Closing
Date of each of the following conditions:

                   6.1.  REPRESENTATIONS.    The  representations  made  by  the
Purchaser in Article III hereof shall be true and correct when made and shall be
true and correct on the Closing Date.


28877_4
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<PAGE>



                   6.2.  LEGAL  INVESTMENT.  At the  time  of the  Closing,  the
purchase  of  the  Securities  shall  be  legally  permitted  by  all  laws  and
regulations to which the Purchaser and the Company are subject.

                   6.3.  PAYMENT  OF  PURCHASE  PRICE.  The  Company  shall have
received payment in full of the purchase price for the Securities.


                                   ARTICLE VII

                              OPTIONAL PREPAYMENTS

                   7.1. OPTIONAL PREPAYMENTS. The Company may, at its option, at
any time prior to maturity,  prepay the  Debenture,  in whole or in part without
premium or penalty at a price equal to the principal amount thereof plus accrued
interest thereon to the date fixed for prepayment. Any prepayments made pursuant
to this  Section  7.1 shall be applied  first to the  payment of interest on and
then to principal of the Debenture at the time outstanding.

                   7.2.  NOTICE OF PREPAYMENT.The right of the Company to prepay
the  Debenture  pursuant  to Section  7.1 shall be  conditioned  upon its giving
notice  of  prepayment,  signed  by its  President  and by its  Treasurer  or an
Assistant  Treasurer,  to the holder of the  Debenture not less than thirty (30)
days prior to the date upon which the prepayment is to be made (the  "Prepayment
Notice"),  specifying (a) the aggregate  principal amount of the Debenture to be
prepaid,  (b) the  date of such  prepayment,  and  (c) the  accrued  and  unpaid
interest (to and  including  the date upon which the  prepayment is to be made).
The Prepayment  Notice having been so given,  the aggregate  principal amount of
the Debenture so specified in such Prepayment Notice, and all accrued and unpaid
interest thereon, shall become due and payable on the specified prepayment date.

                   7.3.  EXERCISE  OF  CONVERSION   PRIVILEGE  UPON  RECEIPT  OF
PREPAYMENT  NOTICE.  Upon  receipt  of a  Prepayment  Notice,  the holder of the
Debenture may at any time up to the third day preceding the specified prepayment
date elect to convert all or a portion of the  outstanding  principal  amount of
the Debenture in accordance with the terms of the Debenture.


                                  ARTICLE VIII

                              AFFIRMATIVE COVENANTS

                  The  Company  hereby  covenants  and  agrees,  so  long as any
Securities remain outstanding, as follows:



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<PAGE>



                   8.1.   MAINTENANCE  OF CORPORATE  EXISTENCE,  PROPERTIES  AND
                          LEASES; TAXES; INSURANCE.

                   (a)  The   Company   shall  and  shall   cause  each  of  its
subsidiaries  to,  maintain  in full force and effect its  corporate  existence,
rights and franchises and all material terms of licenses and other rights to use
licenses,  trademarks,  trade  names,  service  marks,  copyrights,  patents  or
processes owned or possessed by it and necessary to the conduct of its business.

                   (b)  The   Company   shall  and  shall   cause  each  of  its
subsidiaries  to keep each of its  properties  necessary  to the  conduct of its
business in good repair,  working order and condition,  reasonable wear and tear
excepted,  and from time to time make all needful and proper repairs,  renewals,
replacements,  additions  and  improvements  thereto;  and the Company shall and
shall cause its subsidiaries to at all times comply with each material provision
of all leases to which it is a party or under which it occupies property.

                   (c)  The   Company   shall  and  shall   cause  each  of  its
subsidiaries  to promptly pay and discharge,  or cause to be paid and discharged
when due and payable, all lawful taxes,  assessments and governmental charges or
levies  imposed upon the income,  profits,  assets,  property or business of the
Company and its subsidiaries, and all claims or indebtedness (including, without
limitation,  claims or  demands of  workmen,  materialmen,  vendors,  suppliers,
mechanics, carriers, warehousemen and landlords) which, if unpaid might become a
lien  upon the  assets or  property  of the  Company  or  subsidiary;  PROVIDED,
HOWEVER,  that any such tax, assessment,  charge or levy need not be paid if the
validity  thereof  shall be  contested  timely and in good faith by  appropriate
proceedings,  if the  Company  or  subsidiary  shall have set aside on its books
adequate  reserves  with  respect  thereto,  and the failure to pay shall not be
prejudicial  in any  material  respect  to the  holders of the  Securities,  and
PROVIDED,  FURTHER,  that the Company or subsidiary will pay or cause to be paid
any such tax,  assessment,  charge or levy  forthwith upon the  commencement  of
proceedings to foreclose any lien which may have attached as security  therefor.
The Company  shall and shall cause its  subsidiaries  to pay or cause to be paid
all  other   indebtedness   incident  to  the   operations  of  the  Company  or
subsidiaries.

                   (d)  The   Company   shall  and  shall   cause  each  of  its
subsidiaries to keep its assets which are of an insurable  character  insured by
financially sound and reputable  insurers against loss or damage by theft, fire,
explosion and other risks  customarily  insured against by companies in the line
of business of the Company or its subsidiaries, in amounts sufficient to prevent
the Company or its  subsidiaries  from  becoming a  co-insurer  of the  property
insured;  and the Company  shall and shall cause its  subsidiaries  to maintain,
with financially sound and reputable  insurers,  insurance against other hazards
and risks and  liability to persons and property to the extent and in the manner
customary for companies in similar  businesses  similarly  situated or as may be
required by law,  including,  without  limitation,  general liability,  fire and
product liability insurance as may be required pursuant to any license agreement
to which the Company or its subsidiaries is a party or by which it is bound.


28877_4
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<PAGE>



                   8.2. BASIC FINANCIAL  INFORMATION.  The Company shall furnish
the following reports to the Purchaser (or any transferee of any Securities), so
long as the Purchaser is a holder of any Securities:

                   (a) within  forty-five (45) days after the end of each of the
quarterly  accounting  periods  in  each  fiscal  year,  unaudited  consolidated
statements of income and retained earnings and cash flows of the Company and its
subsidiaries  for such quarterly period and for the period from the beginning of
such fiscal year to the end of such quarterly period, together with consolidated
balance  sheets  of the  Company  and  its  subsidiaries  as at the  end of each
quarterly  period,  setting  forth in each  case  comparisons  to  corresponding
periods in the  preceding  fiscal  year,  which  statements  will be prepared in
accordance with generally accepted accounting principles, consistently applied;

                   (b)  within  ninety  (90) days  after the end of each  fiscal
year,  consolidated statements of income and retained earnings and cash flows of
the  Company and its  subsidiaries  for the period  from the  beginning  of each
fiscal year to the end of such fiscal year, and  consolidated  balance sheets as
at the end of such fiscal year,  setting forth in each case in comparative  form
corresponding  figures for the preceding  fiscal year,  which statements will be
prepared  in  accordance   with  generally   accepted   accounting   principles,
consistently  applied  (except as approved by the accounting firm examining such
statements  and disclosed by the Company),  and will be  accompanied by a report
thereon of certified public accountants.

                   (c) promptly as legally permitted,  any additional reports or
other detailed information  concerning significant aspects of the operations and
condition, financial or otherwise, of the Company and its subsidiaries, given to
the Company by its independent accountants;

                   (d)  within  ten (10)  days  after  transmission  or  receipt
thereof, copies of all financial statements,  proxy statements and reports which
the  Company  sends  to  its  stockholders  or  directors,  and  copies  of  all
registration statements and all regular, special or periodic reports which it or
any of its  officers  or  directors  files  with  the  Commission  or  with  any
securities  exchange  on which any of the  securities  of the  Company  are then
listed  or  proposed  to be  listed,  copies  of all  press  releases  and other
statements  made  generally  available  by the Company to the public  concerning
material  developments in the business of the Company and its  subsidiaries  and
copies  of  material  communications  sent  to or  received  from  stockholders,
directors or  committees  of the Board of Directors of the Company or any of its
subsidiaries and copies of all material communications sent to and received from
any lender to the Company; and

                   (e) with  reasonable  promptness  such other  information and
financial  data  concerning  the  Company  as any  person  entitled  to  receive
materials under this Section 8.2 may reasonably request.

                   8.3.  NOTICE OF ADVERSE  CHANGE.  The Company shall  promptly
give notice to all holders of any Securities  (but in any event within seven (7)
days) after  becoming  aware of the  existence  of any  condition or event which
constitutes, or the occurrence of, any of the following:

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<PAGE>




                   (a) any Event of Default;

                   (b) the institution of an action,  suit or proceeding against
the Company before any court,  administrative  agency or arbitrator,  including,
without  limitation,  any  action of a foreign  government  or  instrumentality,
which, if adversely  decided,  could  materially  adversely affect the business,
prospects,  properties,  financial  condition  or results of  operations  of the
Company, whether or not arising in the ordinary course of business; or

                   (c) any  information  relating  to the  Company  which  could
reasonably be expected to materially and adversely affect the assets,  property,
business or condition  (financial or otherwise) of the Company or its ability to
perform the terms of this  Agreement.  Any notice  given under this  Section 8.3
shall  specify  the nature  and period of  existence  of the  condition,  event,
information,  development or  circumstance,  the anticipated  effect thereof and
what actions the Company has taken and/or proposes to take with respect thereto.

                   8.4.  COMPLIANCE WITH  AGREEMENTS;  COMPLIANCE WITH LAWS. The
Company and its subsidiaries shall comply with the material terms and conditions
of all material  agreements,  commitments or instruments to which the Company or
any of its  subsidiaries  is a party or by which  it or they may be  bound.  The
Company  shall and shall  cause each of its  subsidiaries  to duly comply in all
material respects with any material laws,  ordinances,  rules and regulations of
any foreign,  federal,  state or local government or any agency thereof,  or any
writ,  order or decree,  and conform to all valid  requirements  of governmental
authorities relating to the conduct of their respective  businesses,  properties
or assets,  including,  but not  limited  to,  the  requirements  of ERISA,  the
Environmental  Protection  Act,  the  Occupational  Safety and Health  Act,  the
Foreign  Corrupt  Practices  Act and the  rules and  regulations  of each of the
agencies administering such acts.

                   8.5. PROTECTION OF LICENSES, ETC. The Company shall maintain,
defend and protect to the best of its ability  licenses and sublicenses  (and to
the  extent  the  Company  is a licensee  or  sublicensee  under any  license or
sublicense,  as permitted by the license or sublicense  agreement),  trademarks,
trade  names,  service  marks,  patents  and  applications  therefor  and  other
proprietary  information  owned or used by it and shall keep duplicate copies of
any licenses,  trademarks, service marks or patents owned or used by it, if any,
at a secure place selected by the Company.

                  8.6.   ACCOUNTS AND RECORDS; INSPECTIONS.

                  (a)  The  Company  shall keep true  records and books of
account in which full,  true and correct entries will be made of all dealings or
transactions  in  relation  to the  business  and affairs of the Company and its
subsidiaries in accordance with generally accepted accounting principles applied
on a consistent basis.

                   (b) The Company shall permit each holder of any Securities or
any of such  holder's  officers,  employees or  representatives  during  regular
business  hours of the  Company,  upon  reasonable  notice  and as often as such
holder may reasonably  request,  to visit and inspect the offices and properties

28877_4
                                                        12

<PAGE>



of the Company and its  subsidiaries  and (i) to make  extracts or copies of the
books,  accounts  and  records of the Company or its  subsidiaries,  and (ii) to
discuss the affairs,  finances and accounts of the Company and its subsidiaries,
with the Company's (or  subsidiary's)  directors and officers,  its  independent
public accountants, consultants and attorneys.

                   (c) Nothing  contained in this Section 8.6 shall be construed
to limit any rights which a holder of any  Securities (a "Holder") may have with
respect to the books and records of the Company and its subsidiaries, to inspect
its properties or to discuss its affairs, finances and accounts.

                   8.7. NASDAQ OR AMERICAN STOCK EXCHANGE  LISTING.  The Company
will use its best efforts to list its Common Stock on either the NASDAQ SmallCap
Market or American Stock Exchange.

                   8.8. FURTHER ASSURANCES.  From time to time the Company shall
execute and deliver to the Purchaser and the Purchaser shall execute and deliver
to the Company such other  instruments,  certificates,  agreements and documents
and  take  such  other  action  and do all  other  things  as may be  reasonably
requested by the other party in order to implement or  effectuate  the terms and
provisions of this Agreement and any of the Securities.


                                   ARTICLE IX

                               EVENTS OF DEFAULTS

                   9.1.  EVENTS  OF  DEFAULT.  If any of  the  following  events
(herein called an "Event of Default") shall occur and be continuing:

                   (a) if the  Company  shall  default in the payment of (i) any
part of the  principal  of any  Debenture,  when the same  shall  become due and
payable,  whether  at  maturity  or  at  a  date  fixed  for  prepayment  or  by
acceleration or otherwise; or (ii) the interest on any Debenture;  when the same
shall become due and payable,  and such default in the payment of interest shall
have  continued  for ten (10)  days;  and in each case such  default  shall have
continued  without  cure for ten (10) days  after  written  notice  (a  "Default
Notice") is given to the Company of such default; or

                   (b) If the Company shall default in the performance of any of
the covenants  contained in Article VIII and such default  shall have  continued
without  cure (i) for twenty  (20) days  after a Default  Notice is given to the
Company  with  respect to a covenant  relating to any payment of monies under an
agreement  providing  for payments of at least  $50,000 in the aggregate or (ii)
twenty (20) days after a Default  Notice is given to the Company with respect to
default in the case of a covenant  not related to the payment of monies,  by any
holder or holders of the Securities  (the Company to give forthwith to all other
holders of the Securities at the time outstanding  written notice of the receipt
of such Default Notice, specifying the default referred to therein).


28877_4
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<PAGE>



                  Notwithstanding  the  foregoing,   if  any  such  non-monetary
default shall, by its nature,  be reasonably  incapable of being cured within 20
days,  the period  within  which the  Company  shall have the right to cure such
default  shall be extended  for such  period of time as shall  enable it to cure
such default upon the exercise of due diligence.

                  (c) ______ If the Company shall default in the  performance of
any other  material  agreement or covenant  contained in this Agreement and such
default  shall not have  been  remedied  to the  satisfaction  of the  holder or
holders of at least a majority in aggregate  principal  amount of the Debentures
then outstanding, within thirty (30) days after a Default Notice shall have been
given to the Company  (the  Company to give  forthwith  to all other  holders of
Debentures and Shares at the time  outstanding  written notice of the receipt of
such Default Notice, specifying the default referred to therein); or

                  Notwithstanding  the  foregoing,   if  any  such  non-monetary
default shall, by its nature,  be reasonably  incapable of being cured within 20
days,  the period  within  which the  Company  shall have the right to cure such
default  shall be extended  for such  period of time as shall  enable it to cure
such default upon the exercise of due diligence.

                   (d) If any  representation or warranty made in this Agreement
or in or any  certificate  delivered  pursuant  hereto  shall prove to have been
incorrect in any material respect when made; or

                   (e) If any default shall occur under any indenture, mortgage,
agreement,  instrument or  commitment  evidencing or under which there is at the
time outstanding any indebtedness of the Company (or a Material  Subsidiary,  as
hereinafter   defined),   in  excess  of  $50,000,  or  which  results  in  such
indebtedness,  in an aggregate  amount (with other  defaulted  indebtedness)  in
excess of $50,000  becoming  due and  payable  prior to its due date and if such
indenture or instrument so requires, the holder or holders thereof (or a trustee
on their behalf) shall have declared such indebtedness due and payable; or

                   (f) If any of the Company or its  subsidiaries  shall default
in the observance or performance of any material term or provision of a material
agreement  to which it is a party or by which it is bound,  and such  default is
not waived or cured within the applicable grace period; or

                   (g) If a final judgment which,  either alone or together with
other  outstanding  final  judgments  against the Company and its  subsidiaries,
exceeds an  aggregate of $50,000  shall be rendered  against the Company (or any
Material  Subsidiary)  and such judgment  shall have continued  undischarged  or
unstayed for thirty (30) days after entry thereof; or

                   (h) If the Company (or any Material Subsidiary) shall make an
assignment for the benefit of creditors, or shall admit in writing its inability
to pay its debts; or if the Company (or any Material  Subsidiary) shall suffer a
receiver or trustee for it or  substantially  all of its assets to be appointed,
and, if appointed  without its consent,  not to be  discharged  or stayed within
ninety (90) days;  or if the Company (or any Material  Subsidiary)  shall suffer
proceedings   under  any  law  relating  to   bankruptcy,   insolvency   or  the

28877_4
                                                        14

<PAGE>



reorganization  or relief of debtors to be  instituted by or against it, and, if
contested by it, not to be dismissed or stayed  within  ninety (90) days;  or if
the Company (or any Material  Subsidiary) shall suffer any writ of attachment or
execution  or any  similar  process  to be issued or  levied  against  it or any
significant  part of its  property  which is not  released,  stayed,  bonded  or
vacated  within  ninety (90) days after its issue or levy; or if the Company (or
any Material  Subsidiary)  takes  corporate  action in furtherance of any of the
aforesaid purposes or conditions.

                  For purposes of this Section 9.1, "Material  Subsidiary" means
any  subsidiary  with  respect to which the Company has  directly or  indirectly
invested, loaned, advanced or guaranteed the obligations of, an aggregate amount
exceeding  fifteen percent (15%) of the Company's gross assets, or the Company's
proportionate  share  of the  assets  or  net  income  of  which  (based  on the
subsidiary's most recent financial  statements)  exceed fifteen percent (15%) of
the Company's gross assets or net income, respectively, or the gross revenues of
which exceed  fifteen  percent (15%) of the gross  revenues of the Company based
upon the most recent financial statements of such subsidiary and the Company.

                  9.2.     REMEDIES.

                   (a) Upon the occurrence of an Event of Default, any holder or
holders of a majority in aggregate  principal  amount of the  Debentures  at the
time  outstanding  may at any time (unless all defaults shall  theretofore  have
been  remedied)  at its or their  option,  by  written  notice or notices to the
Company (i) declare all the Debentures to be due and payable, whereupon the same
shall  forthwith  mature and  become due and  payable,  together  with  interest
accrued thereon,  without presentment,  demand,  protest or notice, all of which
are hereby waived;  and (ii) declare any other amounts  payable to the Purchaser
under this Agreement or as contemplated hereby due and payable.

                   (b) Notwithstanding  anything contained in Section 9.2(a), in
the event that at any time after the principal of the Debentures shall so become
due and payable and prior to the date of maturity  stated in the  Debentures all
arrears of  principal of and interest on the  Debentures  (with  interest at the
rate  specified in the  Debentures on any overdue  principal  and, to the extent
legally  enforceable,  on any  interest  overdue)  shall  be  paid by or for the
account of the  Company,  then the  holder or holders of at least a majority  in
aggregate principal amount of the Debentures then outstanding, by written notice
or notices to the Company,  may (but shall not be obligated to) waive such Event
of Default and its  consequences and rescind or annul such  declaration,  but no
such waiver shall extend to or affect any subsequent  Event of Default or impair
any right  resulting  therefrom.  If any  holder of a  Debenture  shall give any
notice or take any other action with respect to a claimed default,  the Company,
forthwith  upon  receipt of such  notice or  obtaining  knowledge  of such other
action will give written  notice  thereof to all other holders of the Debentures
then  outstanding,  describing such notice or other action and the nature of the
claimed default.

                   9.3.  ENFORCEMENT.  In case any one or more Events of Default
shall occur and be continuing,  the holder of a Debenture then  outstanding  may
proceed to protect  and  enforce  the rights of such holder by an action at law,
suit in  equity  or  other  appropriate  proceeding,  whether  for the  specific

28877_4
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<PAGE>



performance  of any agreement  contained  herein or in such  Debenture or for an
injunction against a violation of any of the terms hereof or thereof,  or in aid
of the exercise of any power  granted  hereby or thereby or by law.  Each holder
agrees  that  it  will  give  written  notice  to the  other  holders  prior  to
instituting  any  such  action.  In  case of a  default  in the  payment  of any
principal  of or interest on any  Debenture,  the Company will pay to the holder
thereof such  further  amount as shall be  sufficient  to cover the cost and the
expenses of collection,  including,  without limitation,  reasonable  attorney's
fees, expenses and disbursements.  No course of dealing and no delay on the part
of any holder of any  Debenture  in  exercising  any rights  shall  operate as a
waiver thereof or otherwise  prejudice such holder's rights.  No right conferred
hereby or by any  Debenture  upon any holder  thereof  shall be exclusive of any
other right referred to herein or therein or now available at law in equity,  by
statute or otherwise.


                                    ARTICLE X

                              AMENDMENT AND WAIVER

                  This  Agreement  may not be amended,  discharged or terminated
(or any provision  hereof waived) without the written consent of the Company and
the  Purchaser.  Provided  that such  written  consent  of the  Company  and the
Purchaser is given:

                   (a)  Holders of at least a majority  in  aggregate  principal
amount of the Debentures  then  outstanding may by written  instrument  amend or
waive  any  term or  condition  of this  Agreement  relating  to the  rights  or
obligations of holders of Debentures, which amendment or waiver operates for the
benefit of such  holders,  except  that no such  amendment  or waiver  shall (i)
change the fixed  maturity of any  Debenture,  the rate or the time of mandatory
prepayment of principal  thereof or payment of interest  thereon,  the principal
amount thereof,  or the terms of  subordination,  if any, without the consent of
the holder of the Debenture so affected, (ii) change the aforesaid percentage of
Debentures,  the holders of which are required to consent to any such  amendment
or waiver,  without  the  consent  of the  holders  of all the  Debentures  then
outstanding or (iii) change the percentage of the amount of the Debentures,  the
holders of which may declare the  Debentures to be due and payable under Article
IX.

                   (b) The  Company  and  each  holder  of a  Debenture  then or
thereafter  outstanding  shall be bound by any  amendment or waiver  effected in
accordance  with the provisions of this Article X, whether or not such Debenture
shall have been marked to indicate such  modification,  but any Debenture issued
thereafter  shall bear a notation as to any such  modification.  Promptly  after
obtaining the written consent of the holders herein provided,  the Company shall
transmit a copy of such  modification  to all of the  holders of the  Debentures
then outstanding.


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<PAGE>



                                   ARTICLE XI

                     EXCHANGE AND REPLACEMENT OF DEBENTURES

                  11.1.  Subject to Section  12.2, at any time at the request of
any holder of one or more of the  Debentures  to the Company at its office,  the
Company at its expense (except for any transfer tax or any other tax arising out
of the  exchange)  will  issue in  exchange  therefor  new  Debentures,  in such
denomination or denominations ($100,000 or any larger multiple of $100,000, plus
one Debenture in a lesser denomination, if required) as such holder may request,
in  aggregate  principal  amount  equal to the  unpaid  principal  amount of the
Debenture or Debentures surrendered and substantially in the form thereof, dated
as of the date to which  interest has been paid on the  Debenture or  Debentures
surrendered  (or, if no interest  has yet been so paid  thereon,  then dated the
date of the Debenture or Debentures so  surrendered)  and payable to such person
or persons or order as may be designated by such holder.

                  11.2. Upon receipt of evidence  satisfactory to the Company of
the loss, theft,  destruction or mutilation of any Debenture and, in the case of
any such loss,  theft,  or  destruction,  upon  delivery of a bond of  indemnity
satisfactory  to the Company  (provided  that if the holder is a Purchaser  or a
financial institution,  its own agreement will be satisfactory),  or in the case
of any such mutilation,  upon surrender and cancellation of such Debenture,  the
Company  will  issue a new  Debenture  of like  tenor  as if the  lost,  stolen,
destroyed or mutilated  Debenture were then  surrendered for exchange in lieu of
such lost, stolen, destroyed or mutilated Debenture.


                                   ARTICLE XII

                      TRANSFER OF AND PAYMENT OF DEBENTURES

                  12.1.  NOTIFICATION OF PROPOSED SALE.

                   (a) Subject to Section 12.1(b), each holder of a Debenture by
acceptance  thereof  agrees that it will give the Company ten (10) days  written
notice prior to selling or otherwise  disposing of such  Debenture  during which
time the  Company  may  prepay  the  Debenture  in full.  No such  sale or other
disposition  shall be made  unless (i) the holder  shall  have  supplied  to the
Company  an  opinion of counsel  for the  holder  reasonably  acceptable  to the
Company to the effect that no registration  under the Securities Act is required
with  respect  to  such  sale or  other  disposition,  or  (ii)  an  appropriate
registration statement with respect to such sale or other disposition shall have
been filed by the Company and declared effective by the Commission.

                   (b) If the holder of  Debentures  has  obtained an opinion of
counsel reasonably  acceptable to the Company to the effect that the sale of its
Debentures may be made without registration under the Securities Act pursuant to
compliance  with Rule 144 (or any successor rule under the Securities  Act), the
holder need not provide the Company with the notice required in Section 12.1(a).

28877_4
                                                        17

<PAGE>




                   (c) The Company may endorse on all  Debentures an appropriate
legend restricting their transfer except upon compliance with this Section 12.1;
PROVIDED, HOWEVER, that no such legend shall be endorsed on any Debenture which,
when issued,  is no longer subject to the restrictions of this Section 12.1, and
PROVIDED,  FURTHER,  that if an opinion of counsel  satisfactory  to the Company
concludes that the legend is no longer necessary,  the Company will deliver upon
transfer Debentures without such legends.

                   12.2.  PAYMENT.  So long as the Purchaser shall be the holder
of any  Debenture,  the Company will make  payments of principal and interest to
the  Purchaser no later than 11 a.m.  Eastern Time on the date when such payment
is due.  Payments shall be made by delivery to the Purchaser at the  Purchaser's
address  furnished  to the  Company  in  accordance  with  this  Agreement  of a
certified  or  official  bank  check  drawn  upon or issued by a bank which is a
member  of the New York  Clearinghouse  for  banks or by wire  transfer  to such
Purchaser's (or such Purchaser's nominee's) account at any bank or trust company
in the United States of America.  The Purchaser  further agrees that, before the
Debenture is assigned or  transferred,  the  Purchaser  will make or cause to be
made a notation thereon of principal payments previously made thereof and of the
date to which interest  thereon has been paid and will notify the Company of the
name and address of the  transferee  of such  Debenture if such name and address
are known to the Purchaser.


                                  ARTICLE XIII

                             RIGHT OF FIRST REFUSAL


                  13.1.  RIGHT OF FIRST REFUSAL.

                   (a) The  Company  hereby  agrees that if at any time prior to
one year after the Closing Date the Company is considering making an offering of
securities  in a  transaction  which  would not require  registration  under the
Securities Act by virtue of an exemption  therefrom  afforded by Regulation D or
Regulation  S  thereunder,  the  Company  shall  prepare  a term  sheet for such
offering in reasonable detail (the "Term Sheet") and transmit such Term Sheet to
the Purchaser.

                   (b) The  Purchaser  shall  have the right to accept or reject
the terms set forth in the Term Sheet,  which such right must be exercised as to
all (but not less than all) of the securities being offered therein.  Such right
shall be exercisable by the Purchaser  within 20 days after receipt by it of the
Term  Sheet and,  if not  exercised  within  such 20 day time  period,  it shall
expire,  except as elsewhere provided in this Article XIII. If the Term Sheet is
accepted by the  Purchaser,  the Purchaser and the Company as shall be deemed to
have agreed to use their bona fide best efforts to consummate the transaction on
the terms set forth in the Term Sheet as promptly as possible. If the Term Sheet
is rejected  by the  Purchaser,  or if the  Purchaser  does not serve  notice of
acceptance of the Term Sheet within the aforesaid  20-day  period,  the Company,
without further obligation of any kind, including any requirement to give notice
to  the  Purchaser,  may  make  one  or  more  offerings  to  third  parties  on

28877_4
                                                        18

<PAGE>



substantially  the  same  terms  as those  set  forth  in the  Term  Sheet or on
different  terms  which in the  reasonable  opinion  of the  Company  are in the
aggregate  more  favorable  to the Company  than the terms set forth in the Term
Sheet,  and if such offer is accepted by any such third party, the Company shall
be free to consummate such offering in accordance with its terms.

                   (c) If the Company  shall have  followed the  procedures  set
forth in subparagraphs  (a) and (b) hereof,  but no transaction  shall have been
consummated  within 120 days with the  Purchaser or any third party  pursuant to
the terms of the Term Sheet which shall have been  distributed,  such Term Sheet
shall be withdrawn by the Company from  circulation  and the  provisions of this
Article XIII shall be applicable AB INITIO to any new Term Sheet.

                   (d) If the Company  shall receive an offer from a third party
prospective investor with respect to the Term Sheet referred to in subparagraphs
(a) and (b) hereof,  which is modified in any material  business  respect to the
benefit of such  investor and the  detriment of the Company,  such modified Term
Sheet  shall  not be  accepted  by the  Company  until it shall  have  given the
Purchaser  the right to accept the terms as so  modified,  which  right shall be
exercisable  by the  Purchaser  for 15 days after  receipt of the modified  Term
Sheet.  Failure to accept the  modified  Term Sheet  within the  aforesaid  time
period shall conclusively be deemed to be a rejection thereof.

                   (e) If the Company  shall  comply with the  provision of this
Article XIII,  and  consummate  Regulation D or Regulation S transaction  with a
third party  investor upon the terms and  conditions  contemplated  hereby,  the
right of First  Refusal  granted to the  Purchaser  in this  Article  XIII shall
terminate  and  be  of  no  further  force  and  effect   immediately  upon  the
consummation of such transaction.


                                   ARTICLE XIV

                                  MISCELLANEOUS

                   14.1.  GOVERNING  LAW.  This  Agreement and the rights of the
parties  hereunder shall be governed in all respects by the laws of the State of
New York.

                   14.2. SURVIVAL.  The representations,  warranties,  covenants
and  agreements  made herein  shall  survive (a) any  investigation  made by the
Purchaser and (b) the Closing.

                   14.3.  SUCCESSORS AND ASSIGNS.  Except as otherwise expressly
provided  herein,  the  provisions  hereof shall inure to the benefit of, and be
binding upon and  enforceable by and against,  the successors,  assigns,  heirs,
executors and administrators of the parties hereto; PROVIDED,  HOWEVER, that the
Company may not assign its rights hereunder.

                   14.4.  ENTIRE  AGREEMENT.   This  Agreement   (including  the
Exhibits  hereto)  and  the  other  documents   delivered  pursuant  hereto  and
simultaneously  herewith  constitute  the  full  and  entire  understanding  and
agreement  between the parties  with  regard to the  subject  matter  hereof and
thereof.

28877_4
                                                        19

<PAGE>



                   14.5.   NOTICES,   ETC.   All   notices,   demands  or  other
communications  given  hereunder  shall be in writing and shall be  sufficiently
given if  delivered  either  personally  or by a nationally  recognized  courier
service  marked for next  business day delivery or sent in a sealed  envelope by
first class mail, postage prepaid and either registered or certified,  addressed
as follows:

                (a)     if to the Company:

                          Advanced Viral Research Corp.
                             200 Corporate Boulevard
                             Yonkers, New York 10701
                           Attention:  Shalom Z. Hirschman, M.D., President and
                                         Chief Executive Officer

                (b)     if to the  Purchaser,  to the  address  set forth on the
                        first page of this Agreement.

or to such other address with respect to any party hereto as such party may from
time to time  notify (as  provided  above) the other  parties  hereto.  Any such
notice,  demand or  communication  shall be deemed to have been given (i) on the
date of delivery, if delivered personally,  (ii) one business day after delivery
to a nationally  recognized  overnight  courier service,  if marked for next day
delivery or (iii) five business days after the date of mailing, if mailed.

                   Copies of any notice,  demand or  communication  given to the
Company,  shall be delivered to Lowenthal,  Landau,  Fischer & Bring,  P.C., 250
Park Avenue, New York, New York, 10177, Attn.: Robert E. Fischer,  Esq., or such
other address as may be directed.

                   14.6.  DELAYS OR OMISSIONS.  No delay or omission to exercise
any right,  power or remedy  accruing to any holder of any  Securities  upon any
breach or default of the  Company  under this  Agreement  shall  impair any such
right,  power or remedy of such holder nor shall it be  construed to be a waiver
of any such  breach  or  default,  or an  acquiescence,therein,  or of or in any
similar  breach or  default  thereafter  occurring;  nor shall any waiver of any
single  breach or  default  be deemed a waiver  of any other  breach or  default
theretofore or thereafter occurring.  Any waiver, permit, consent or approval of
any kind or character  on the part of any holder of any breach or default  under
this  Agreement,  or any waiver on the part of any holder of any  provisions  or
conditions  of this  Agreement  must be, made in writing and shall be  effective
only to the extent specifically set forth in such writing. All remedies,  either
under this  Agreement  or by law or otherwise  afforded to any holder,  shall be
cumulative and not alternative.

                   14.7.  RIGHTS;   SEVERABILITY.   Unless  otherwise  expressly
provided  herein,  each  Purchaser's  rights  hereunder are several rights,  not
rights  jointly  held  with any  other  person.  In case any  provision  of this
Agreement shall be invalid, illegal or unenforceable, the validity, legality and
enforceability  of the remaining  provisions shall not in any way be affected or
impaired thereby.


28877_4
                                                        20

<PAGE>



                  14.8.     AGENT'S FEES.

                   (a) The  Company  hereby (i)  represents  and  warrants  that
except for Interfi  Group,  Inc.  ("Interfi"),  the  Company has not  retained a
finder  or broker  in  connection  with the  transactions  contemplated  by this
Agreement and (ii) agrees to indemnify and to hold the Purchaser harmless of and
from any liability for  commission or  compensation  in the nature of an agent's
fee to any  broker,  person  or firm  (including  Interfi),  and the  costs  and
expenses of defending against such liability or asserted  liability,  including,
without  limitation,  reasonable  attorney's  fees,  arising from any act by the
Company or any of the Company's employees or representatives; PROVIDED, HOWEVER,
that the  Company  will have the  right to  defend  against  such  liability  by
representative(s) of its own choosing,  and PROVIDED,  FURTHER, that the Company
will not settle or compromise any claim or lawsuit  without prior written notice
to the  Purchaser  of the terms and  provisions  thereof.  In the event that the
Company shall fail to undertake  the defense  within ten (10) days of any notice
of such claim,  the  Purchaser  shall have the right to  undertake  the defense,
compromise  or  settlement  of such claim upon written  notice to the Company by
holders of a majority in principal amount of the Debentures and the Company will
be  responsible  for and  shall pay all costs and  expenses  of  defending  such
liability or asserted liability and any amounts paid in settlement.

                   (b) The  Purchaser  (i)  represents  and warrants that it has
retained no finder or broker in connection with the transactions contemplated by
this  Agreement  and (ii) hereby  severally  agrees to indemnify and to hold the
Company  harmless from any liability for any commission or  compensation  in the
nature of an agent's or finder's  fee to any broker or other person or firm (and
the costs,  including  reasonable legal fees, and expenses of defending  against
such liability or asserted  liability) for which such  Purchaser,  or any of its
employees or representatives, are responsible.

                   14.9.  EXPENSES.  Each  of the  parties  shall  bear  its own
expenses and legal fees incurred on its behalf with respect to the  negotiation,
execution and consummation of the transactions contemplated by this Agreement.

                  14.10. LITIGATION. The parties each hereby waive trial by jury
in any  action  or  proceeding  of any kind or  nature  in any court in which an
action may be commenced  arising out of this Agreement or by reason of any other
cause or dispute  whatsoever  between  them.  The parties  hereto agree that the
State and  Federal  Courts  which sit in the State of New York and the County of
New York shall have exclusive  jurisdiction  to hear and determine any claims or
disputes between the Company and such holders, pertaining directly or indirectly
to this Agreement or to any matter arising therefrom. The parties each expressly
submit and consent in advance to such  jurisdiction  in any action or proceeding
commenced in such courts  provided that such consent shall not be deemed to be a
waiver of personal  service of the summons and  complaint,  or other  process or
papers issued therein. The choice of forum set forth in this Section 14.10 shall
not be deemed to preclude the enforcement of any judgment obtained in such forum
or the  taking  of any  action  under  this  Agreement  to  enforce  same in any
appropriate jurisdiction.  The parties each waive any objection based upon forum
non conveniens and any objection to venue of any action instituted hereunder.


28877_4
                                                        21

<PAGE>



                   14.11.  TITLES AND  SUBTITLES.  The  titles of the  articles,
sections and subsections of this Agreement are for convenience of reference only
and are not to be considered in construing this Agreement.

                   14.12.  COUNTERPARTS.  This  Agreement may be executed in any
number of  counterparts,  each of which shall be an  original,  but all of which
together shall constitute one instrument.

                  If the  Purchaser  is in  agreement  with  the  foregoing  the
Purchaser  shall sign where  indicated  below and  thereupon  this letter  shall
become a binding agreement between the Purchaser and the Company.

                          Very truly yours,
                          ADVANCED VIRAL RESEARCH CORP.

                          By:
                                   Shalom Z. Hirschman, M.D., President and
                                   Chief Executive Officer


AGREED:

RBB BANK AKTIENGESELLSCHAFT


By:


28877_4
                                                        22

<PAGE>





                                    EXHIBIT A

             FORM OF 7% CONVERTIBLE DEBENTURE DUE FEBRUARY 28, 2007


               $                                                          , 1997
 ----------------                                                      
                                                              New York, New York

                  FOR VALUE RECEIVED,  ADVANCED VIRAL RESEARCH CORP., a Delaware
corporation (the "undersigned" or the "Company"),  hereby promises to pay to the
order   of   ____________________________   ,  at   its   offices   located   at
________________________________________  or at such  other  place as the holder
hereof shall  designate to the  undersigned  in writing,  in lawful money of the
United  States of America or in New York  Clearing  House Funds,  the  principal
amount of Dollars,  and to pay interest (computed on the basis of a 360-day year
and the actual number of days elapsed) on the unpaid  principal amount hereof at
the rate of seven (7%) percent per annum.  The  undersigned  promises to pay the
said principal sum and interest as follows:

                  Until this  Debenture is  completely  retired the  undersigned
shall make  payments of accrued  interest on this  Debenture on the first day of
January and July in each year  (commencing  with July 1, 1997),  computed at the
rate of 7% per annum on the unpaid  principal  balance of this Debenture for the
period from the date of this Debenture until the date of such interest  payment.
On February 28, 2007 the undersigned  shall pay the holder all unpaid  principal
and interest on this Debenture.

                  Interest on the indebtedness evidenced by this Debenture after
default or maturity  accelerated  or  otherwise  shall be due and payable at the
rate of ten (10%) percent per annum,  subject to the  limitations  of applicable
law.

                  If this  Debenture or any  installment  hereof becomes due and
payable on a Saturday,  Sunday or public  holiday under the laws of the State of
New York, the due date hereof shall be extended to the next succeeding  business
day and  interest  shall be payable at the rate of seven (7%)  percent per annum
during such  extension.  All  payments  received by the holder  shall be applied
first to the payment of all accrued interest payable hereunder.

                  Subject to and in compliance with the provisions  hereof,  the
holder  shall  have the right to  convert  all or a portion  of the  outstanding
principal  amount of this  Debenture into such number of shares of Common Stock,
par value  $.00001 per share,  of the Company  ("Common  Stock")  (the shares of
Common Stock issuable upon conversion of this Debenture are hereinafter referred
to as the "Conversion  Shares") as shall equal the quotient obtained by dividing
(x) the principal amount of this Debenture to be converted by (y) the Applicable
Conversion  Price (as  hereinafter  defined) and by surrender of this Debenture,
such surrender to be made in the manner provided herein; PROVIDED, HOWEVER, that

28877_4

<PAGE>



the right to convert outstanding  principal of this Debenture shall terminate at
the close of business on the third  calendar  day  preceding  the date fixed for
prepayment unless the Company shall default in making such prepayment.

         For purposes hereof the term "Applicable  Conversion  Price" shall mean
the lesser of (q) $ and (r) the product  obtained by multiplying (i) the Average
Closing Price (as hereinafter defined) by (iii) .70.

         For  purposes  hereof the "Average  Closing  Price" with respect to any
conversion  elected to be made by the holder  shall be the  average of the daily
closing  prices for the five  consecutive  trading days ended on the trading day
immediately  preceding  the date on which the holder gives the Company a written
notice  of the  holder's  election  to  convert  outstanding  principal  of this
Debenture. The closing price on any trading day shall be (a) if the Common Stock
is then listed or quoted on either the NASD Bulletin Board,  the NASDAQ SmallCap
Market or the NASDAQ  National  Market,  the reported  closing bid price for the
Common  Stock on such day or (b) if the  Common  Stock is listed  on either  the
American  Stock  Exchange or New York Stock  Exchange,  the last reported  sales
price for the Common Stock on such exchange on such day.

         On the date notice is  delivered  in order to exercise  its  conversion
right,  the holder shall  surrender this Debenture to the Company at its office,
accompanied  by written  notice to the Company that the holder  hereof elects to
convert  all  or a  specified  portion  of the  outstanding  principal  of  this
Debenture (the "Conversion Notice"). Within five (5) business days after receipt
of this Debenture and the Conversion  Notice, the Company will pay to the holder
all interest  accrued on the principal  amount of this Debenture to be converted
to the effective date of conversion or, at the sole option of the Company, issue
to the holder in lieu thereof such  additional  number of shares of Common Stock
as shall equal the  quotient  obtained by dividing  the total  amount of accrued
interest  on the  principal  amount of this  Debenture  to be  converted  by the
Applicable  Conversion Price.  Within five (5) business days after the surrender
of this  Debenture as aforesaid,  the Company shall cause its transfer  agent to
issue and deliver to such holder,  or on its written  order,  a  certificate  or
certificates  without any restrictive legend thereon for the number of shares of
Common  Stock  issuable  upon  the  conversion  hereof  in  accordance  with the
provisions of this Debenture,  and any fractional interest in respect of a share
of Common Stock  arising upon such  conversion  shall be settled as  hereinafter
provided.  If the  Company  fails to  deliver  to the  holder a  certificate  or
certificates  for shares of Common Stock as aforesaid prior to the expiration of
five (5) business days after receipt of the  Conversion  Notice and surrender to
the Company of the Debenture, the Company shall pay to the holder a penalty. The
penalty shall be $1,000 if the  certificate  or  certificates  are not delivered
until the sixth business day after the delivery of the Conversion Notice and the
penalty shall double every business day until the  certificate  or  certificates
are so  delivered,  but in no event  shall such  penalty  exceed  $100,000.  For
example,  if the  certificates  are  delivered on the eighth  business day after
delivery of the  Conversion  Notice and  surrender of the  Debenture the penalty
shall be $4,000.

         If the entire  outstanding  principal  amount of this  Debenture is not
converted,  the  Company  shall  also  issue and  deliver  to such  holder a new
Debenture of like tenor in the principal amount equal to the principal which was
not converted and dated the effective date of conversion.  Each conversion shall
be deemed to have been  effected  immediately  prior to the close of business on
the date on which this  Debenture  shall have been  surrendered  and such notice
received by the Company as aforesaid, and the person or persons in whose name or

28877_4
                                                         2

<PAGE>



names any  certificate  of  certificates  for  shares of Common  Stock  shall be
issuable  upon such  conversion  shall be deemed to have  become  the  holder or
holders of record of the shares  represented  thereby at such time on such date.
All shares of Common Stock  delivered upon  conversion of this  Debenture  will,
upon  delivery,   be  duly  authorized,   validly  issued  and  fully  paid  and
nonassessable.  No  fractional  shares of  Common  Stock  shall be  issued  upon
conversion of this  Debenture.  Instead of any fractional  share of Common Stock
which would otherwise be deliverable  upon the conversion of a principal of this
Debenture the Company shall pay to the holder an amount in cash (computed to the
nearest cent) equal to the Average Closing Price multiplied by the fraction of a
share of Common Stock represented by such fractional interest.

         Notwithstanding anything to the contrary contained herein, (x) until 45
days after the Closing  Date (as defined in the  Securities  Purchase  Agreement
dated  February  21, 1997  between the  Company and  _____________________  (the
"Purchase  Agreement"))  the holder may not elect to convert  any portion of the
principal of this Debenture, (y) until 60 days after the Closing Date the holder
may not elect to  convert  more than  33-1/3%  of the  principal  amount of this
Debenture  and (z) until 90 days after the Closing Date the holder may not elect
to convert more than 66- 2/3% of the principal amount of this Debenture.

                  The issuance of  certificates  for shares of Common Stock upon
any  conversion  of this  Debenture  shall be made  without  charge to the payee
hereof  for  any  tax or  other  expense  in  respect  to the  issuance  of such
certificates,  all of which taxes and expenses shall be paid by the Company, and
such  certificates  shall be issued only in the name of the registered holder of
this Debenture.

                  This  Debenture  has  been  issued  pursuant  to and  shall be
subject  to all of the  provisions  of the  Purchase  Agreement.  The  payee  is
entitled to the benefits of the Purchase  Agreement,  and this  Debenture may be
prepaid as provided in the Purchase Agreement. Reference is made to Sections 7.2
and 7.3 of the Purchase  Agreement  with respect to certain rights of the holder
to  convert  this  Debenture  into  Common  Stock  upon  receipt  of a notice of
prepayment.

                  Upon  the  occurrence  of any  one or more  of the  events  of
default  specified  or referred  to in the  Purchase  Agreement  or in the other
documents or  instruments  executed in  connection  therewith,  all amounts then
remaining  unpaid on this  Debenture may be declared to be  immediately  due and
payable as provided in the Purchase Agreement.

                  In the event that this Debenture  shall be placed in the hands
of an attorney for collection by reason of any event of default  hereunder,  the
undersigned agrees to pay reasonable attorney's fees and disbursements and other
reasonable  expenses  incurred by the payee in connection with the collection of
this Debenture.

                  The rights,  powers and remedies given to the payee under this
Debenture shall be in addition to all rights, powers and remedies given to it by
virtue of the  Purchase  Agreement,  any  document  or  instrument  executed  in
connection therewith, or any statute or rule of law.

                  Any  forbearance,  failure or delay by the payee in exercising
any right,  power or remedy under this Debenture,  the Purchase  Agreement,  any

28877_4
                                                         3

<PAGE>



documents or instruments executed in connection therewith or otherwise available
to the payee shall not be deemed to be a waiver of such right,  power or remedy,
nor shall any single or partial exercise of any right,  power or remedy preclude
the further exercise thereof.

                  No  modification or waiver of any provision of this Debenture,
the Purchase  Agreement or any documents or  instruments  executed in connection
therewith  shall be  effective  unless it shall be in writing  and signed by the
payee,  and any such  modification  or waiver  shall apply only in the  specific
instance for which given.

                  This  Debenture and the rights and  obligations of the parties
hereto,  shall be governed,  construed and interpreted  according to the laws of
the State of New York,  and the  undersigned  consents and agrees that the State
and Federal Courts which sit in the State of New York,  County of New York shall
have exclusive jurisdiction of all controversies and disputes arising hereunder.

                  The term "payee" as used herein shall be deemed to include the
payee and its successors, endorsees and assigns.

                  The undersigned hereby waives presentment, demand for payment,
protest, notice of protest and notice of non-payment hereof.


                                    By:
                                       Shalom Z. Hirschman, M.D., President and
                                            Chief Executive Officer



28877_4
                                                         4

<PAGE>



                                    EXHIBIT B



<TABLE>
<CAPTION>
NAME AND ADDRESS OF                                     SECURITY PURCHASED              PURCHASE PRICE
PURCHASER

<S>                        <C>                                                          <C>
                           $1,000,000 principal amount
                           of 7% Convertible Debenture
                                             due February 28, 2007                      $____________

                           Warrant to purchase 178,378
                           shares of Common Stock, par
                           value $.00001 per share in
                                             the form of Exhibit D-1                    $_____________

                           Warrant to purchase 178,378
                           shares of Common Stock, par
                           value $.00001 per share in
                                             the form of Exhibit D-2                    $_____________

                           Warrant to purchase 178,378
                           shares of Common Stock, par
                           value $.00001 per share in
                                             the form of Exhibit D-3                    $_____________

</TABLE>


28877_4

<PAGE>


EXHIBIT 2
                                            INTERFI CAPITAL GROUP,INC.
                                             3867 Holcomb Bridge Road
                                                     Suite 800
                                             Norcross, Georgia  30092

                                                 December 16, 1997



Advanced Viral Research Corp.
5240 Blackstone Avenue
Riverdale, NY  10471

Attn:  Shalom Z. Hirschman, M.D.
       President and CEO

                Re: Advanced Viral Research Corp. (the "Company")

Dear Dr. Hirschman:

                  This  letter  will set forth the terms and  conditions  of our
agreement  to serve as a "finder" in  connection  with the capital  needs of the
Company as follows:

                   1.  Interfi  Capital  Group,  Inc.  ("ICG")  shall act as the
Company's "finder" from the date hereof through February 17, 1997.

                   2. ICG will use its best  efforts in good  faith to  identify
possible  sources of capital in the amount of from  $8,0000,000 to  $10,000,000.
You  acknowledge  that our role is primarily one of introducing to you investors
having a legitimate  interest in meeting the capital needs of companies  such as
yours and that the precise terms and  conditions  of any such capital  infusion,
including whether it takes the form of debt or equity and any conversion rights,
warrants or the like are matters of negotiation between the Company and any such
investor. ICG shall act as a finder rather than as an agent or broker.

                  3. In  consideration  of ICG  providing  its  services  to the
Company, the Company agrees to pay to ICG a fee equal to seven percent (7.0%) of
any funds raised by the Company from any sources  introduced  by ICG through the
public  or  private  sale of  equity  or debt  securities,  whether  or not such
financing is completed  during the term of this agreement or for a period of one
year  subsequent to the date that this agreement has otherwise  terminated.  Our
fee is due and payable on the day upon which the closing of any such transaction
occurs.  The Company shall also issue to ICG, warrants to purchase  one-third of
one percent of the then outstanding shares of the Company exercisable at 150% of
the bid price of the Company's  common stock on the day of closing,  exercisable
for a period of 30 months after closing.  During the term of this agreement,  if
the Company receives a capital infusion from any other source, the Company shall
pay to ICG a fee of three and one-half percent (3.5%) of such funds.


32629_1

<PAGE>



                  4. Company  shall  reimburse ICG for all  reasonable  expenses
incurred by ICG in connection  with its services  performed in  accordance  with
this  agreement,  including  but not limited  to,  attorneys'  fees,  travel and
lodging expenses,  printing  expenses,  overnight courier or delivery  services,
postage and other shipping  expenses,  on-line computer charges payable to third
parties, and photocopying  expenses,  provided such expenses are approved (which
approval shall not be unreasonably  withheld) by the Company.  Reimbursement  of
such expenses shall be due and payable 30 days after Company's  receipt of ICG's
invoice(s)  and which  payment  shall  survive  the  termination  of this letter
agreement and not be conditioned upon closing of the  transactions  contemplated
hereby.  The Company shall be  responsible  for the fees and expenses of its own
counsel.

                  5. For  purposes  of this  agreement,  closing  shall mean the
receipt  by  Company  of a  capital  infusion  either  during  the  term of this
agreement or from sources  identified by ICG or introduced to the Company by ICG
within a period of one year after termination of this agreement.

                  6. Company  shall retain  counsel to review and  negotiate all
documents  and to  determine  whether  any  securities  sold or  issued by it in
connection with the  transactions  contemplated  hereby need to be registered or
qualified in accordance  with federal and various states' blue sky laws, and, if
advised by counsel to do so,  effect at its own  expense  such  registration  or
qualification.

                  7. Upon Closing,  ICG shall be entitled to place a "tombstone"
advertisement  in various  publications  subject to  Company's  approval  of the
contents of such advertisement.

                  8. This  agreement  shall be governed  by,  and  construed  in
accordance with, the laws of the State of New York.

                  9. The person  signing  this  letter on behalf of the  Company
represents  and warrants that he is authorized to do so and that this  agreement
constitutes the valid and binding obligation of the Company.

                  10. It is expressly  understood that the Company  reserves the
right, in the exercise of its sole discretion,  to accept or reject any proposal
for investment derived from a source initiated by ICG.

                  11.  Within  twenty-four  hours  of  delivery  of a  facsimile
executed copy of this agreement to ICG, ICG shall disclose to the Company and/or
its  counsel  the  names of  prospective  investors.  If,  for any  reason,  the
disclosure  is not made  within  that  time  period,  or the  investors  are not
acceptable to the Company in the exercise of its discretion,  the Company may by
written  notice  delivered  on or  before  December  28,  1996,  terminate  this
agreement ab initio. In such event, the Company will not engage in any financial
transaction  with any  prospective  investor  whose  name was  disclosed  to the
Company for a period of five years or disclose the names of such investors, this
clause surviving any termination of this agreement.

                   12.  ICG   represents  and  warrants  that  (a)  neither  its
officers,  directors or shareholders nor any person associated with ICG has been

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<PAGE>


sanctioned by the Securities  Exchange Commission within the last five years and
(b) that none of the foregoing have unsavory backgrounds.

                  If the foregoing is acceptable  to you,  please  indicate your
acceptance  thereof by signing the enclosed  copy of this letter  agreement  and
returning it to me at your earliest convenience.

                  We look forward to working with you.

                                         Sincerely,

                                         INTERFI CAPITAL GROUP, INC.

                                         /s/ Alex H. C. Pannell

                                         Alex H.C. Pannell
                                         Managing Director


ACCEPTED, this 17th day of December, 1996.

ADVANCED VIRAL RESEARCH CORP.

By:  /S/ SHALOM Z. HIRSCHMAN
    Shalom Z. Hirschman, M.D.
    President and CEO



cc:  Robert E. Fischer, Esq. (via telefax)


32629_1

<PAGE>

EXHIBIT 3
                          ADVANCED VIRAL RESEARCH CORP.
                 7% CONVERTIBLE DEBENTURE DUE FEBRUARY 28, 2007


  $1,000,000                                                   February 21, 1997
                                                              New York, New York

                           FOR VALUE RECEIVED, ADVANCED VIRAL RESEARCH CORP.,
a Delaware corporation (the "undersigned" or the "Company"),  hereby promises to
pay to the  order of RBB Bank AG at its  offices  located  at c/o ABN AMRO  Bank
N.V.,  New York,  New York or at such  other  place as the holder  hereof  shall
designate to the undersigned in writing, in lawful money of the United States of
America or in New York Clearing House Funds, the principal amount of One Million
Dollars,  and to pay  interest  (computed on the basis of a 360-day year and the
actual number of days elapsed) on the unpaid principal amount hereof at the rate
of seven  (7%)  percent  per annum.  The  undersigned  promises  to pay the said
principal sum and interest as follows:

                          Until  this   Debenture  is  completely   retired  the
undersigned  shall make  payments of accrued  interest on this  Debenture on the
first day of  January  and July in each  year  (commencing  with July 1,  1997),
computed  at the rate of 7% per annum on the  unpaid  principal  balance of this
Debenture for the period from the date of this Debenture  until the date of such
interest payment.  On February 28, 2007 the undersigned shall pay the holder all
unpaid principal and interest on this Debenture.

                          Interest  on  the   indebtedness   evidenced  by  this
Debenture  after default or maturity  accelerated or otherwise  shall be due and
payable at the rate of ten (10%) percent per annum,  subject to the  limitations
of applicable law.

                          If this  Debenture or any  installment  hereof becomes
due and payable on a Saturday,  Sunday or public  holiday  under the laws of the
State of New York, the due date hereof shall be extended to the next  succeeding
business day and interest shall be payable at the rate of seven (7%) percent per
annum  during such  extension.  All  payments  received  by the holder  shall be
applied first to the payment of all accrued interest payable hereunder.

                          Subject  to  and in  compliance  with  the  provisions
hereof,  the  holder  shall  have the right to  convert  all or a portion of the
outstanding  principal  amount of this  Debenture  into such number of shares of
Common Stock,  par value $.00001 per share, of the Company ("Common Stock") (the
shares  of  Common  Stock  issuable  upon   conversion  of  this  Debenture  are
hereinafter  referred to as the "Conversion Shares") as shall equal the quotient
obtained by dividing (x) the principal  amount of this Debenture to be converted
by (y) the Applicable Conversion Price (as hereinafter defined) and by surrender
of this  Debenture,  such  surrender to be made in the manner  provided  herein;
PROVIDED,  HOWEVER,  that the right to  convert  outstanding  principal  of this
Debenture  shall  terminate  at the close of business on the third  calendar day
preceding  the date fixed for  prepayment  unless the Company  shall  default in
making such prepayment.


31570_1
                                                         1

<PAGE>



                  For purposes  hereof the term  "Applicable  Conversion  Price"
shall mean the lesser of (q) $0.3432 and (r) the product obtained by multiplying
(i) the Average Closing Price (as hereinafter defined) by (iii) .70.

                  For purposes  hereof the "Average  Closing Price" with respect
to any  conversion  elected to be made by the holder shall be the average of the
daily closing prices for the five consecutive  trading days ended on the trading
day  immediately  preceding  the date on which the  holder  gives the  Company a
written notice of the holder's election to convert outstanding principal of this
Debenture. The closing price on any trading day shall be (a) if the Common Stock
is then listed or quoted on either the NASD Bulletin Board,  the NASDAQ SmallCap
Market or the NASDAQ  National  Market,  the reported  closing bid price for the
Common  Stock on such day or (b) if the  Common  Stock is listed  on either  the
American  Stock  Exchange or New York Stock  Exchange,  the last reported  sales
price for the Common Stock on such exchange on such day.

                  On the date  notice  is  delivered  in order to  exercise  its
conversion  right,  the holder shall  surrender this Debenture to the Company at
its office,  accompanied by written notice to the Company that the holder hereof
elects to convert all or a specified  portion of the  outstanding  principal  of
this Debenture (the  "Conversion  Notice").  Within five (5) business days after
receipt of this Debenture and the Conversion Notice, the Company will pay to the
holder all  interest  accrued on the  principal  amount of this  Debenture to be
converted  to the  effective  date of  conversion  or, at the sole option of the
Company, issue to the holder in lieu thereof such additional number of shares of
Common Stock as shall equal the  quotient  obtained by dividing the total amount
of accrued interest on the principal amount of this Debenture to be converted by
the  Applicable  Conversion  Price.  Within  five (5)  business  days  after the
surrender of this  Debenture as aforesaid,  the Company shall cause its transfer
agent  to  issue  and  deliver  to  such  holder,  or on its  written  order,  a
certificate or certificates  without any  restrictive  legend thereon (except if
the Company  reasonably  believes  the holder to be an affiliate of the Company)
for the number of shares of Common Stock issuable upon the conversion  hereof in
accordance with the provisions of this Debenture, and any fractional interest in
respect of a share of Common Stock arising upon such conversion shall be settled
as  hereinafter  provided.  If the  Company  fails to  deliver  to the  holder a
certificate or certificates for shares of Common Stock as aforesaid prior to the
expiration of five (5) business days after receipt of the Conversion  Notice and
surrender to the Company of the Debenture, the Company shall pay to the holder a
penalty.  The penalty shall be $1,000 if the certificate or certificates are not
delivered  until the sixth  business  day after the  delivery of the  Conversion
Notice and the penalty shall double every business day until the  certificate or
certificates  are so  delivered,  but in no  event  shall  such  penalty  exceed
$100,000.  For example, if the certificates are delivered on the eighth business
day after delivery of the  Conversion  Notice and surrender of the Debenture the
penalty shall be $4,000.

                  If the entire  outstanding  principal amount of this Debenture
is not converted,  the Company shall also issue and deliver to such holder a new
Debenture of like tenor in the principal amount equal to the principal which was
not converted and dated the effective date of conversion.  Each conversion shall
be deemed to have been  effected  immediately  prior to the close of business on
the date on which this  Debenture  shall have been  surrendered  and such notice
received by the Company as aforesaid, and the person or persons in whose name or
names any  certificate  of  certificates  for  shares of Common  Stock  shall be

31570_1
                                                         2

<PAGE>



issuable  upon such  conversion  shall be deemed to have  become  the  holder or
holders of record of the shares  represented  thereby at such time on such date.
All shares of Common Stock  delivered upon  conversion of this  Debenture  will,
upon  delivery,   be  duly  authorized,   validly  issued  and  fully  paid  and
nonassessable.  No  fractional  shares of  Common  Stock  shall be  issued  upon
conversion of this  Debenture.  Instead of any fractional  share of Common Stock
which would otherwise be deliverable  upon the conversion of a principal of this
Debenture the Company shall pay to the holder an amount in cash (computed to the
nearest cent) equal to the Average Closing Price multiplied by the fraction of a
share of Common Stock represented by such fractional interest.

                  Notwithstanding anything to the contrary contained herein, (x)
until 45 days after the  Closing  Date (as  defined in the  Securities  Purchase
Agreement  dated  February  21,  1997  between  the Company and RBB Bank AG (the
"Purchase  Agreement"))  the holder may not elect to convert  any portion of the
principal of this Debenture, (y) until 60 days after the Closing Date the holder
may not elect to  convert  more than  33-1/3%  of the  principal  amount of this
Debenture  and (z) until 90 days after the Closing Date the holder may not elect
to convert more than 66- 2/3% of the principal amount of this Debenture.

                          The  issuance  of  certificates  for  shares of Common
Stock upon any conversion of this Debenture  shall be made without charge to the
payee  hereof for any tax or other  expense in respect to the  issuance  of such
certificates,  all of which taxes and expenses shall be paid by the Company, and
such  certificates  shall be issued only in the name of the registered holder of
this Debenture.

                          This  Debenture has been issued  pursuant to and shall
be subject to all of the  provisions  of the  Purchase  Agreement.  The payee is
entitled to the benefits of the Purchase  Agreement,  and this  Debenture may be
prepaid as provided in the Purchase Agreement. Reference is made to Sections 7.2
and 7.3 of the Purchase  Agreement  with respect to certain rights of the holder
to  convert  this  Debenture  into  Common  Stock  upon  receipt  of a notice of
prepayment.

                          Upon the  occurrence  of any one or more of the events
of default  specified or referred to in the  Purchase  Agreement or in the other
documents or  instruments  executed in  connection  therewith,  all amounts then
remaining  unpaid on this  Debenture may be declared to be  immediately  due and
payable as provided in the Purchase Agreement.

                          In the event  that this  Debenture  shall be placed in
the hands of an  attorney  for  collection  by  reason  of any event of  default
hereunder,  the  undersigned  agrees  to  pay  reasonable  attorney's  fees  and
disbursements and other reasonable  expenses incurred by the payee in connection
with the collection of this Debenture.

                          The  rights,  powers and  remedies  given to the payee
under this  Debenture  shall be in addition to all rights,  powers and  remedies
given to it by virtue of the  Purchase  Agreement,  any  document or  instrument
executed in connection therewith, or any statute or rule of law.

                          Any  forbearance,  failure  or delay  by the  payee in
exercising  any  right,  power or remedy  under  this  Debenture,  the  Purchase
Agreement,  any documents or  instruments  executed in  connection  therewith or

31570_1
                                                         3

<PAGE>


otherwise  available  to the  payee  shall  not be deemed to be a waiver of such
right,  power or remedy,  nor shall any single or partial exercise of any right,
power or remedy preclude the further exercise thereof.

                          No  modification  or waiver of any  provision  of this
Debenture,  the Purchase  Agreement or any documents or instruments  executed in
connection therewith shall be effective unless it shall be in writing and signed
by the  payee,  and any such  modification  or waiver  shall  apply  only in the
specific instance for which given.

                          This  Debenture and the rights and  obligations of the
parties hereto,  shall be governed,  construed and interpreted  according to the
laws of the State of New York, and the undersigned  consents and agrees that the
State and Federal Courts which sit in the State of New York,  County of New York
shall have exclusive  jurisdiction  of all  controversies  and disputes  arising
hereunder.

                          The term  "payee"  as used  herein  shall be deemed to
include the payee and its successors, endorsees and assigns.

                          The undersigned hereby waives presentment,  demand for
payment, protest, notice of protest and notice of non-payment hereof.

                          ADVANCED VIRAL RESEARCH CORP.



By:
Shalom Z. Hirschman, M.D.,
President and
Chief Executive Officer


31570_1
                              4

<PAGE>

EXHIBIT 4
                                WARRANT TO PURCHASE
                     COMMON STOCK, PAR VALUE $.00001 PER SHARE
                                        OF
                           ADVANCED VIRAL RESEARCH CORP.

      -----------------------------------------------------------------------


          This Warrant has not been registered under the Securities Act
          of 1933, as amended (the "Act"), because the issuance thereof
            is believed to be exempt from registration under various
                     regulations promulgated under such Act.

                  This  certifies  that,  for  value  received,  RBB Bank AG, or
registered  assigns  ("Warrantholder"),  is entitled to purchase  from  ADVANCED
VIRAL RESEARCH CORP. (the "Company"), subject to the provisions of this Warrant,
at any time and from time to time  until  5:00  p.m.  Eastern  Standard  Time on
February  21, 2007  178,378  shares of the  Company's  Common  Stock,  par value
$.00001 per share  ("Warrant  Shares").  The  purchase  price  payable  upon the
exercise of this Warrant  shall be $0.288 per Warrant  Share.  The Warrant Price
and the number of Warrant Shares which the Warrantholder is entitled to purchase
is subject to adjustment upon the occurrence of the  contingencies  set forth in
Section 3 of this  Warrant,  and as adjusted  from time to time,  such  purchase
price is hereinafter referred to as the "Warrant Price."

                  This Warrant is subject to the following terms and conditions:

                  1.       EXERCISE OF WARRANT.

                          (a) This  Warrant may be exercised in whole or in part
but not for a fractional  share. Upon delivery of this Warrant at the offices of
the Company or at such other  address as the Company may  designate by notice in
writing to the  registered  holder  hereof with the  Subscription  Form  annexed
hereto duly executed, accompanied by payment of the Warrant Price for the number
of Warrant  Shares  purchased (in cash,  by certified,  cashier's or other check
acceptable to the Company,  by Common Stock of the Company having a Market Value
(as  hereinafter  defined) equal to the aggregate  Warrant Price for the Warrant
Shares to be purchased,  or any  combination of the  foregoing),  the registered
holder  of  this  Warrant  shall  be  entitled  to  receive  a  certificate   or
certificates   for  the  Warrant  Shares  so  purchased.   Such  certificate  or
certificates shall be promptly delivered to the Warrantholder.  Upon any partial
exercise of this Warrant, the Company shall execute and deliver a new Warrant of
like tenor for the balance of the Warrant Shares purchasable hereunder.

                          (b) In lieu of  exercising  this  Warrant  pursuant to
Section  1(a),  the holder may elect to receive  shares of Common Stock equal to
the value of this  Warrant  determined  in the  manner  described  below (or any
portion  thereof  remaining  unexercised)  upon  delivery of this Warrant at the
offices of the Company or at such other  address as the Company may designate by
notice in writing to the  registered  holder  hereof with the Notice of Cashless
Exercise  Form annexed  hereto duly  executed.  In such event the Company  shall


31575_1

<PAGE>



issue to the holder a number of shares of the  Company's  Common Stock  computed
using the following formula:

                            X = Y (A-B)
                                 A

Where X = the number of shares of Common Stock to be issued to the holder.

          Y       = the number of shares of Common Stock  purchasable under this
                  Warrant (at the date of such calculation).

          A       = the  Market  Value  of the  Company's  Common  Stock  on the
                  business day immediately preceding the day on which the Notice
                  of Cashless Exercise is received by the Company.

          B = Warrant Price (as adjusted to the date of such calculation).

                            (c) The Warrant Shares deliverable  hereunder shall,
upon issuance,  be fully paid and  non-assessable and the Company agrees that at
all times  during the term of this  Warrant it shall  cause to be  reserved  for
issuance  such  number of shares of its Common  Stock as shall be  required  for
issuance and delivery upon exercise of this Warrant.

                            (d) For purposes of this  Warrant,  the Market Value
of a share of Common  Stock on any date shall be equal to (i) the  closing  sale
price per share as published by a national  securities  exchange on which shares
of Common Stock (or other units of the security) are traded (an  "Exchange")  on
such date or, if there is no sale of Common  Stock on such date,  the average of
the bid and asked  prices on such  exchange at the close of trading on such date
or,  (ii) if shares of Common  Stock  are not  listed on a  national  securities
exchange on such date,  the closing price per share as published on the National
Association of Securities Dealers Automatic Quotation System ("NASDAQ") National
Market System if the shares are quoted on such system on such date, or (iii) the
average of the bid and asked prices in the over-the-counter  market at the close
of trading on such date if the shares are not traded on an exchange or listed on
the NASDAQ National Market System,  or (iv) if the Common Stock is not traded on
a national  securities  exchange  or in the  over-the-counter  market,  the fair
market value of a share of Common Stock on such date as determined in good faith
by the Board of Directors. If the holder disagrees with the determination of the
Market  Value  of any  securities  of the  Company  determined  by the  Board of
Directors under Section  1(d)(iv) the Market Value of such  securities  shall be
determined by an independent  appraiser acceptable to the Company and the holder
(or, if they cannot  agree on such an  appraiser,  by an  independent  appraiser
selected by each of them, and Market Value shall be the median of the appraisals
made by such appraisers).  If there is one appraiser,  the cost of the appraisal
shall be shared  equally  between the  Company and the holder.  If there are two
appraisers,  each of the Company and the holder shall pay for its own appraisal.
2. TRANSFER OR ASSIGNMENT OF WARRANT.

                            (a) Any assignment or transfer of this Warrant shall
be made by  surrender  of this  Warrant at the offices of the Company or at such

31575_1
                                                         2

<PAGE>



other address as the Company may designate in writing to the  registered  holder
hereof with the Assignment  Form annexed hereto duly executed and accompanied by
payment of any requisite transfer taxes, and the Company shall,  without charge,
execute and deliver a new Warrant of like tenor in the name of the  assignee for
the portion so assigned in case of only a partial assignment, with a new Warrant
of like tenor to the assignor for the balance of the Warrant Shares purchasable.

                            (b)  Prior to any  assignment  or  transfer  of this
Warrant,  the holder  thereof shall deliver an opinion of counsel to the Company
to the effect that the proposed  transfer may be effected  without  registration
under the Act.

    3.       ADJUSTMENT OF WARRANT PRICE AND WARRANT SHARES -- ANTI-DILUTION
             PROVISIONS.

                       A.  (1)  Except  as  hereinafter  provided,  in case  the
              Company  shall at any time after the date hereof  issue any shares
              of Common Stock (including shares held in the Company's  treasury)
              without consideration, then, and thereafter successively upon each
              issuance,  the Warrant Price in effect  immediately  prior to each
              such issuance shall forthwith be reduced to a price  determined by
              multiplying the Warrant Price in effect  immediately prior to such
              issuance by a fraction:

              (a)      the  numerator  of which  shall be the  total  number  of
                       shares of Common Stock  outstanding  immediately prior to
                       such issuance, and

              (b)      the  denominator  of which  shall be the total  number of
                       shares of Common Stock outstanding immediately after such
                       issuance.

                  For the purposes of any  computation  to be made in accordance
with the  provisions  of this  clause (1),  the  following  provisions  shall be
applicable:

                       (i)         Shares of  Common  Stock  issuable  by way of
                                   dividend or other  distribution  on any stock
                                   of the  Company  shall be deemed to have been
                                   issued and to be  outstanding at the close of
                                   business  on the  record  date  fixed for the
                                   determination  of  stockholders  entitled  to
                                   receive such  dividend or other  distribution
                                   and  shall  be  deemed  to have  been  issued
                                   without consideration. Shares of Common Stock
                                   issued otherwise than as a dividend, shall be
                                   deemed  to  have  been   issued   and  to  be
                                   outstanding  at the close of  business on the
                                   date of issue.

                       (ii)        The  number of shares of Common  Stock at any
                                   time outstanding shall not include any shares
                                   then  owned or held by or for the  account of
                                   the Company.

31575_1
                                                         3

<PAGE>



     (2)      In case the  Company  shall at any time  subdivide  or combine the
              outstanding  shares of  Common  Stock,  the  Warrant  Price  shall
              forthwith  be  proportionately   decreased  in  the  case  of  the
              subdivision   or   proportionately   increased   in  the  case  of
              combination  to the nearest one cent.  Any such  adjustment  shall
              become  effective  at the close of  business on the date that such
              subdivision or combination shall become effective.

                       B. In the event that the number of outstanding  shares of
              Common Stock is increased by a stock dividend payable in shares of
              Common  Stock or by a  subdivision  of the  outstanding  shares of
              Common Stock, which may include a stock split, then from and after
              the time at which the adjusted  Warrant  Price  becomes  effective
              pursuant to the  foregoing  Subsection A of this Section by reason
              of such  dividend or  subdivision,  the number of shares  issuable
              upon the exercise of this Warrant shall be increased in proportion
              to such  increase  in  outstanding  shares.  In the event that the
              number of  outstanding  shares of Common  Stock is  decreased by a
              combination of the outstanding  shares of Common Stock, then, from
              and after the time at which the  adjusted  Warrant  Price  becomes
              effective  pursuant to such Subsection A of this Section by reason
              of such  combination,  the  number  of  shares  issuable  upon the
              exercise of this Warrant  shall be decreased in proportion to such
              decrease in outstanding shares.

                       C. In the event of an  adjustment  of the Warrant  Price,
              the  number  of shares of  Common  Stock (or  reclassified  stock)
              issuable upon exercise of this Warrant after such adjustment shall
              be equal to the number determined by dividing:

                           (1)     an  amount  equal to the  product  of (i) the
                                   number of shares  of  Common  Stock  issuable
                                   upon  exercise  of this  Warrant  immediately
                                   prior  to  such  adjustment,   and  (ii)  the
                                   Warrant  Price   immediately  prior  to  such
                                   adjustment, by

                           (2)     the  Warrant  Price  immediately  after  such
                                   adjustment.

                       D. In the case of any reorganization or  reclassification
              of the outstanding  shares of Common Stock (other than a change in
              par value, or from par value to no par value, or from no par value
              to par value,  or as a result of a subdivision or  combination) or
              in the case of any consolidation of the Company with, or merger of
              the Company with, another corporation, or in the case of any sale,
              lease or conveyance of all, or substantially all, of the property,
              assets,  business  and  goodwill of the Company as an entity,  the
              holder  of this  Warrant  shall  thereafter  have the  right  upon

31575_1
                                                         4

<PAGE>

              exercise  to  purchase  the kind and amount of shares of stock and
              other securities and property receivable upon such reorganization,
              reclassification, consolidation, merger or sale by a holder of the
              number of shares of Common  Stock which the holder of this Warrant
              would have received had all Warrant Shares  issuable upon exercise
              of  this   Warrant   been   issued   immediately   prior  to  such
              reorganization,  reclassification,  consolidation, merger or sale,
              at a price equal to the Warrant Price then in effect pertaining to
              this Warrant  (the kind,  amount and price of such stock and other
              securities to be subject to adjustment as herein provided).

                       E. In case the  Company  shall,  at any time prior to the
              expiration  of this  Warrant  and prior to the  exercise  thereof,
              dissolve,  liquidate  or wind up its  affairs,  the  Warrantholder
              shall be entitled,  upon the exercise thereof, to receive, in lieu
              of the  Warrant  Shares of the  Company  which it would  have been
              entitled to  receive,  the same kind and amount of assets as would
              have been  issued,  distributed  or paid to it upon  such  Warrant
              Shares of the Company,  had it been the holder of record of shares
              of Common  Stock  receivable  upon the exercise of this Warrant on
              the record date for the determination of those entitled to receive
              any such  liquidating  distribution.  After any such  dissolution,
              liquidation  or winding up which shall result in any  distribution
              in excess of the Warrant Price  provided for by this Warrant,  the
              Warrantholder  may at its option  exercise the same without making
              payment  of the  aggregate  Warrant  Price  and in such  case  the
              Company shall upon the distribution to said Warrantholder consider
              that the  aggregate  Warrant Price has been paid in full to it and
              in making settlement to said Warrantholder,  shall deduct from the
              amount  payable  to such  Warrantholder  an  amount  equal  to the
              aggregate Warrant Price.

                       F. In case the  Company  shall,  at any time prior to the
              expiration of this Warrant and prior to the exercise  thereof make
              a  distribution  of assets  (other than cash) or securities of the
              Company to its stockholders (the "Distribution") the Warrantholder
              shall be  entitled,  upon the  exercise  thereof,  to receive,  in
              addition to the Warrant Shares it is entitled to receive, the same
              kind and  amount  of  assets  or  securities  as would  have  been
              distributed  to it in the  Distribution  had it been the holder of
              record of shares of Common Stock  receivable upon exercise of this
              Warrant on the record date for  determination of those entitled to
              receive the Distribution.

                       G.  Irrespective  of any  adjustments  in the  number  of
              Warrant  Shares  and the  Warrant  Price or the  number or kind of
              shares purchasable upon exercise of this Warrant, this Warrant may
              continue  to express  the same price and number and kind of shares
              as originally issued.

                   4.  OFFICER'S  CERTIFICATE.  Whenever  the  number of Warrant
Shares and the  Warrant  Price  shall be  adjusted  pursuant  to the  provisions
hereof,  the Company shall forthwith file, at its principal  executive  office a
statement,  signed by the Chairman of the Board,  President,  or one of the Vice
Presidents  of the  Company  and by its Chief  Financial  Officer  or one of its

31575_1
                                                         5

<PAGE>



Treasurers  or  Assistant  Treasurers,  stating the  adjusted  number of Warrant
Shares and the new Warrant  Price  calculated  to the nearest one  hundredth and
setting  forth in  reasonable  detail  the method of  calculation  and the facts
requiring  such  adjustment  and upon  which  such  calculation  is based.  Each
adjustment  shall remain in effect until a  subsequent  adjustment  hereunder is
required. A copy of such statement shall be mailed to the Warrantholder.

                  5. CHARGES,  TAXES AND EXPENSES.  The issuance of certificates
for Warrant  Shares  upon any  exercise of this  Warrant  shall be made  without
charge to the  Warrantholder  for any tax or other  expense  in  respect  to the
issuance of such certificates,  all of which taxes and expenses shall be paid by
the  Company,  and such  certificates  shall be  issued  only in the name of the
Warrantholder.

                  6.       MISCELLANEOUS.

                            (a) The terms of this Warrant  shall be binding upon
and shall inure to the benefit of any  successors  or assigns of the Company and
of the holder or holders  hereof  and of the  shares of Common  Stock  issued or
issuable upon the exercise hereof.

                            (b) No holder  of this  Warrant,  as such,  shall be
entitled to vote or receive  dividends or be deemed to be a  stockholder  of the
Company  for any  purpose,  nor shall  anything  contained  in this  Warrant  be
construed to confer upon the holder of this  Warrant,  as such,  any rights of a
stockholder of the Company or any right to vote, give or withhold consent to any
corporate action, receive notice of meetings,  receive dividends or subscription
rights, or otherwise.

                            (c)  Receipt of this  Warrant  by the holder  hereof
shall  constitute  acceptance  of  an  agreement  to  the  foregoing  terms  and
conditions.

                            (d) The Warrant and the  performance  of the parties
hereunder  shall be construed and interpreted in accordance with the laws of the
State of New York and the parties hereunder consent and agree that the State and
Federal  Courts  which sit in the  State of New York and the  County of New York
shall have exclusive jurisdiction with respect to all controversies and disputes
arising hereunder.

                            (e) Shares  issued  upon  exercise  of this  Warrant
shall be legended substantially as follows:

                  "The  shares  evidenced  by this  certificate  have  not  been
                  registered  under the Securities Act of 1933, as amended,  and
                  must be held indefinitely unless they are transferred pursuant
                  to an effective registration statement under that Act or after
                  receipt of an opinion of counsel  satisfactory  to the Company
                  that registration is not required."


31575_1
                                                6

<PAGE>




                  IN WITNESS WHEREOF,  the Company has caused this Warrant to be
signed by its duly  authorized  officer  and its  corporate  seal to be  affixed
hereto.

Dated: February 21, 1997

                                     ADVANCED VIRAL RESEARCH CORP.



                                 BY:
                                          Shalom Hirschman, M.D.
                                          President

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                                                         7

<PAGE>



                                                 SUBSCRIPTION FORM


                                     (TO BE EXECUTED BY THE REGISTERED HOLDER
                                      IF HE DESIRES TO EXERCISE THE WARRANT)


         To:      ADVANCED VIRAL RESEARCH CORP.


                  The  undersigned   hereby  exercises  the  right  to  purchase
_________  shares of Common Stock,  par value $.00001 per share,  covered by the
attached  Warrant  in  accordance  with the terms and  conditions  thereof,  and
herewith makes payment of the Warrant Price for such shares in full.



                                                     SIGNATURE



                                                     ADDRESS







DATED:


31575_1

<PAGE>



                    NOTICE OF EXERCISE OF COMMON STOCK WARRANT
              PURSUANT TO NET ISSUE ("CASHLESS") EXERCISE PROVISIONS


                                                                         , 199



Advanced Viral Research Corp.         Aggregate Price of            $
a Delaware corporation                of Warrant
[address]
                                      Aggregate Price Being
                                      Exercised:                    $
Attention:
                                      Warrant Price
                                      (per share):                  $
                                      Number of Shares of
                                      Common Stock to be
                                      Issued Under this
                                      Notice:






                                                 CASHLESS EXERCISE


Gentlemen:

                  The undersigned,  registered holder of the Warrant to Purchase
Common Stock delivered herewith  ("Warrant")  hereby irrevocably  exercises such
Warrant for, and  purchases  thereunder,  shares of the Common Stock of ADVANCED
VIRAL RESEARCH CORP., a Delaware  corporation,  as provided  below.  Capitalized
terms used herein,  unless  otherwise  defined  herein,  shall have the meanings
given in the  Warrant.  The  portion  of the  Aggregate  Price  (as  hereinafter
defined)  to be applied  toward the  purchase of Common  Stock  pursuant to this
Notice of Exercise is $ , thereby  leaving a remainder  Aggregate Price (if any)
equal  to $ .  Such  exercise  shall  be  pursuant  to the  net  issue  exercise
provisions  of Section  1(b) of the  Warrant;  therefore,  the  holder  makes no
payment with this Notice of Exercise. The number of shares to be issued pursuant
to this exercise shall be determined by reference to the formula in Section 1(b)
of the Warrant which requires the use of the Market Value (as defined in Section
1(d)  of the  Warrant)  of the  Company's  Common  Stock  on  the  business  day
immediately  preceding  the day on which this Notice is received by the Company.
To the extent the foregoing  exercise is for less than the full Aggregate  Price
of the Warrant,  the  remainder of the Warrant  representing  a number of Shares
equal to the quotient  obtained by dividing the remainder of the Aggregate Price
by the  Warrant  Price (and  otherwise  of like form,  tenor and  effect) may be
exercised under Section 1(a) of the Warrant. For purposes of this

31575_1

<PAGE>



Notice the term "Aggregate  Price" means the product obtained by multiplying the
number of shares of Common Stock for which the Warrant is exercisable  times the
Warrant Price.




                                                     SIGNATURE



DATE:
                                                     ADDRESS



31575_1
                                                         2

<PAGE>


                                                    ASSIGNMENT


                                     (To be Executed by the Registered Holder
                                      if he Desires to Transfer the Warrant)


                  FOR VALUE RECEIVED,  the undersigned hereby sells, assigns and
transfers  unto the right to purchase  shares of Common Stock of ADVANCED  VIRAL
RESEARCH  CORP.,  evidenced by the within Warrant,  and does hereby  irrevocably
constitute and appoint Attorney to transfer the said Warrant on the books of the
Company, with full power of substitution.


                                                     SIGNATURE




                                                     ADDRESS

DATED:

IN THE PRESENCE OF:




31575_1
                                                         3

<PAGE>

EXHIBIT 5
                                     ROBERT C. KOLODNY, M.D.: CURRICULUM VITAE

OFFICE ADDRESS:

         Behavioral Medicine Institute
         885 Oenoke Ridge Road
         New Canaan, CT 06840

OFFICE TELEPHONE:                  (203) 966-8060

OFFICE FAX:                        (203) 966-9807

SOCIAL SECURITY NUMBER:            ###-##-####

DATE OF BIRTH:                     7/7/44

CITIZENSHIP:                       US

EDUCATION:

         Columbia University, NY, NY, B.A., Major in Zoology, 1961-65
         Washington University School of Medicine, St. Louis, MO, M.D. 1965-1969

PROFESSIONAL EXPERIENCE:

          Medical  Director  and  Chairman  of the  Board,  Behavioral  Medicine
                   Institute, New Canaan, CT 1983-present

         Consultant - Masters & Johnson Institute, St. Louis, MO, 1983-present

          Associate Director and Director of Training, Masters & Johnson
                   Institute, St. Louis, MO, 1977-1983

          Lecturer, Department of Psychiatry, Washington University School of
                   Medicine, St. Louis, MO, 1981-1983

          Assistant Director, Masters & Johnson Institute, St. Louis, MO.,
                   1975-1976

          Head of Endocrine Research Section; Head of Continuing Medical
                   Education, Masters & Johnson Institute, St. Louis, MO.,
                   1973-1983

          Head of Infertility Program, Masters & Johnson Institute, St.
                   Louis, MO., 1973-1977

          Attending Physician, Department of Medicine, The Jewish Hospital of
                   St. Louis, St. Louis, MO, 1973-1983

          Clinical and Research Associate, Masters & Johnson Institute, St.
                   Louis, MO., 1972-1974

          Instructor, Department of Medicine, Washington University School of
                   Medicine, St. Louis, MO, 1971-1983


32632_1

<PAGE>


ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 2




          Fellow,  Metabolism Division, Washington University School of
                   Medicine, St. Louis, MO, 1971-1972

          Assistant Resident, Department of Medicine, New England Deaconess
                   Hospital (Harvard Medical School), Boston, MA 1970-1971

          Intern,  Department of Medicine, New England Deaconess Hospital
                   (Harvard Medical School), Boston, MA 1969-1970

BUSINESS EXPERIENCE:

         Founder and Managing General Partner of six investment partnerships
with aggregate assets of approximately $34 million:

                  KBS Partnership (begun in 1981)
                  KBS II Investment Partnership, L.P. (begun in 1983)
                  KBS III Investment Partnership, L.P. (begun in 1984)
                  KBS IV Limited Partnership (begun in 1990)
                  KBS New Dimensions, L.P. (begun in 1994)
                  KBS Global Opportunities, L.P. (begun in 1995)

Board of Directors, Gabelli-O'Connor Treasurer's Fund, Greenwich, CT,
1987-present

Board of Directors, Lynch Corporation (an Amex-listed company), Greenwich, CT,
1988-1994

Board of Directors, Tremont Partners (a financial consulting/pension plan search
firm that went public in 1993), New Canaan, CT 1988-1993

Board of Directors, Steri-Pharm, Scarsale, NY, 1983-1987

Venture capital consultant to numerous start-up operations in fields including
medical technology (for Cornell University Medical School), computer services,
and publishing, 1983-present

MILITARY SERVICE:

Major (Retired), Medical Corps., United States Army Reserves (service terminated
May 1977)

MEDICAL LICENSURE:

Permanent License, Missouri, No. 32200 (issued June 21, 1969)
Permanent License, New York, No. 136207 (issued October 20, 1978)
Permanent License, Connecticut, No. 24157 (issued November 2, 1982)



32632_1

<PAGE>


ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 3




CERTIFICATION:

Certified Sex Therapist and Sex Educator, American Association of Sex Educators,
Counselors, and Therapists, 1976

Diplomate, American Board of Family Practice, 1978-1985

Diplomate, American Board of Sexology, 1988

AWARDS:

Society  for the Scientific Study of Sex, National Award, 1983 (for research
         excellence and contributions to the field of sexology)
American Medical Association Physicians Recognition Award: 1972, 1977, 1980
Elected as a Charter Member, International Academy of Sex Research, 1973
Recipient of Award from LIBRARY JOURNAL for one of the Best Books on Science and
          Technology, 1986, for ON SEX AND HUMAN LOVING, co-authored with
          William H. Masters and Virginia E. Johnson
Recipient of Award from the New York Public Library for one of the Best Books
for Teenagers for 1986, for SMART CHOICES, co-authored with Nancy J. Kolodny and
Thomas E. Bratter, 1987

SOCIETIES:

American Association for the Advancement of Science - Member
American Association of Marriage and Family Therapy - Clinical Member
American Association of Sex Educators, Counselors, and Therapists
         Member; Founding Chairperson, Ethics Committee; Chairperson,
         1982 Annual Meeting; Board of Directors 1983-1985
American Diabetes Association - Member
American Fertility Society - Member
American Geriatrics Society - Member
American Medical Association - Member
Endocrine Society - Member
International Academy of Sex Research - Charter Member
New York Academy of Sciences - Member
Sex Information and Education Council of the United States - Member
Society for Sex Therapy and Research - Member; Executive Committee, 1983-1985
Society for the Scientific Study of Sexuality - Fellow

JOURNAL AFFILIATIONS:

JOURNAL OF HOMOSEXUALITY - Editorial Board (1975-1977) SEXUALITY AND DISABILITY
- - Consulting Editor (1977-1981) JOURNAL OF SEX EDUCATION & THERAPY - Consulting
Editor (1978-1988) ANDROLOGY - Referee ANNALS OF INTERNAL MEDICINE - Referee

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<PAGE>


ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 4




DIABETES - Referee
JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION - Referee
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM - Referee
LIFE SCIENCES - Referee
SCIENCE - Referee

MISCELLANEOUS:

National Science Foundation - Reviewer
National Institute of Arthritis and Metabolic Diseases - Reviewer
National Institute of Mental Health - Reviewer
ENCYCLOPEDIA OF BIOETHICS - Reviewer
Washington Post - Book reviewer
Committee for Medical School Course in Human Sexuality, Washington University
          School of Medicine, 1978-1983
Board of Directors, Masters & Johnson Institute, 1981-1988 Board of Directors,
Missouri Clinical & Biochemical Laboratory, 1979-1983 Board of Directors,
Steri-Pharm, Scarsdale, NY, 1983-1987 Board of Directors, Gabelli-O'Connor
Treasurer's Fund, Greenwich, CT, 1987- National Board of Advocates, Planned
Parenthood, 1990- Board of Directors, Lynch Corporation, Greenwich, CT 1988-1994
Advisory Board, Americans for a Sound AIDS Policy, 1991

PUBLICATIONS:

1.        Kolodny, Robert C. Herpes gestationis: A new assessment of incidence,
diagnosis, and fetal prognosis. American Journal of Obstetrics and Gynecology
10:39-45, May 1, 1969.

2.        Kolodny, Robert C. Observations on the new Masters and Johnson report.
Medical Aspects of Human Sexuality 4:46-60, July 1970.

3.        Kolodny, Robert C. Sexual dysfunction in diabetic females. Diabetes
20:557-559, August 1971.

4.        Kolodny, Robert C. Koehler, Barbara C., Toro, Gelson, and Masters, 
William H. Sperm- agglutinating antibodies and infertility. Obstetrics and
Gynecology 38:576-582, October 1971.

5.        Kolodny, Robert C., Masters, William. Hendryx, Julie, and Toro, 
Gelson. Plasma testosterone and semen analysis in male homosexuals. New England
Journal of Medicine 285:1170-1174, November 1971.

6.        Kolodny, Robert C., Jacobs, Laurence S. Masters, William H. Toro, 
Gelson, and Daughaday, William H. Plasma gonadotropins and prolactin in male
homosexuals. Lancet II: 18-20, July 1, 1972.

7.        Kolodny, Robert C., Jacobs, Laurence S., and Daughaday, William H. 
Mammary stimulation causes prolactin release in women, Nature 238:284, August 4,
1972.

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ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 5





8.        Toro, Golson, Kolodny, Robert C., Masters, William H. Jacobs, Laurence
S., and Daughaday, William H. Failure of alcohol to alter pituitary and target
organ hormone levels (abst.) Clinical Research 21:205, 1973.

9.        Kolodny, Robert C. and Masters, William H. Hormones and homosexuality.
Annals of Internal Medicine 79:397, December 1973.

10.      Kolodny, Robert C. Masters, William H., Kolodner, Robert M. and Toro, 
Gelson. Depression of plasma testosterone levels after chronic intensive
marihuana use. New England Journal of Medicine 290:872-874, 1974.

11.      Kolodny, Robert C., Kahn, Charles B., Goldstein, Howard H. and Barnett,
Donald M. Sexual dysfunction in diabetic men. Diabetes 23:306-310, April 1974

12.      Kolodny, Robert C.  Testimony concerning research in reproduction and 
marihuana. Internal Security Subcommittee, U.S. Senate. Marihuana-Hashish
Epidemic and Its Impact on United States Security. Washington, D.C., U.S.
Government Printing Office, 117-126, 1974.

13.      Kolodny, Robert C. Diabetis and sexual function.  Ortho Panel Vol. 21, 
Ortho Pharmaceuticals, Raritan, New Jersey, 1974.

14.      Kolodny, Robert C. Research issues in the study of marihuana and male 
reproductive physiology in humas. In Marihuana and Health, Tinklenberg, J.R.
(ed.). New York: Academic Press, 1975, pp. 71-81.

15.      Kolodny, Robert C., Lessin, Phyllis J., Toro, Gelson, Masters, William 
H. and Cohen, Sidney. Depression of plasma testosterone with acute marihuana
administration. In Pharmacology of Marihuana, Braude, M.C., and Szara S. (eds.)
Vol. 1 New York: Raven Press, 1976, pp. 217-225.

16.      Kolodny, Robert C. Ethical requirements for sex research in humans: 
Informed consent and general issues. In Ethical Issues in Sex Therapy and
Research, Masters, W.H., Johnson, V.E. and Kolodny, R.C. (eds). Boston: Little,
Brown, 1977, pp. 52-69.

17.      Masters, Wiliam H., Johnson, Virginia E., and Kolodny, Robert C. (eds).
Ethical Issues in Sex Therapy and Research. Boston: Little, Brown, 1977.

18.      Kolodny, Robert C.  Ethical issues in the prevention of sexual 
problems. In Qualls, B. (ed), Prevention of Sexual Problems. New York: Plenum
Press. 1978, pp.183-196.

19.      Seto, T., Tricomi, S., Goodwin, D., Kolodny, R.C., and Sullivan, M. 
Biochemical correlatos of ethanol induced flushing. Journal of Studies on
Alcohol 39:1-11, 1978.

20.      Frank, D., Dornbush, R.L., Webster, S.K., and Kolodny, R.C. Mastectomy 
and sexual behavior: a pilot study. Sexuality and Disability 1: 16-26, 1978.


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<PAGE>


ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 6


21.      Kolodny, R.C. Effects of alpha-methyldopa on male sexual function. 
Sexuality and Disability 1:22-228, 1978.

22.      Kolodny, R.C. Conference report: Ethical guidelines for research and 
clinical perspectives on human sexuality. Newsletter on Science, Technology, and
Human Values, No.24, pp. 17-22, June 1978.

23.      Masters, W.H., Johnson, V.E., Kolodny, R.C., and Tullman, G.D.  IN VIVO
Evaluation of an effervescent intravaginal contraceptive insert by simulated
coital activity. Fertility and Sterility 32:161- 165, 1979.

24.      Kolodny, R.C., Masters, W.H., and Johnson, V.E. Textbook of Sexual 
Medicine. Boston: Little, Brown, 1979. (Subsequently published in a Spanish
edition).

25.      Kolodny, R.C., Masters, W.H., Johnson, V.E., and Biggs, M.A. Textbook 
of Human Sexuality for Nurses. Boston: Little, Brown, 1979.

26.      Kolodny, R.C., and Bauman, J.E. Female sexual activity at ovulation. 
New England Journal of Medicine 300: 626, 1979.

27.      Masters, W.H., Kolodny, R.C., and Johnson-Masters, V.E. IN VIVO testing
of intravaginal contraceptives. In Vaginal Contraceptions: New Developments,
G.I. Zatuchni, A.J. Sobrero, J.J. Speidel, and J.J. Sciarra (eds.). Hagerstown,
MD: Harper & Row, 1979. pp.256-262.

28.      Schwartz, M.F., Kolodny, R.C., and Masters, W.H.  Plasma testosterone 
levels of sexually functional and dysfunctional men. Archives of Sexual Behavior
9:355-366, 1980.

29.      Masters, W.H., Johnson, V.E. Kolodny, R.C., and Weems, S. (eds.) 
Ethical Issues in Sex Therapy and Research: Volume II. boston : Little, Brown,
1980.

30. Tullman, G.M., Gilner, F.H., Kolodny, R.C., Dornbush, R.L., and Tullman, G.
The pre- and post-therapy measurement of communication skills of couples
undergoing sex therapy at the Masters and Johnson Institute. Archives of Sexual
Behavior 10:95-109, 1981.

31.      Kolodny, R.C.  Evaluating sex therapy: Process and outcome at the 
Masters & Johnson Institute. Journal of Sex Research 17:301-318, 1981.

32.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. Human Sexuality.  
Boston: Little, Brown, 1982. (Subsequently published in Spanish edition.)

33.      Bauman, J.E., Kolodny, R.C., and Webster, S.K.  Vaginal organic acids 
and hormonal changes in the menstrual cycle. Fertility and Sterility 38:
572-579, 1982.

34.      Clifford, R.E., and Kolodny, R.C. Sex therapy for couples. In B.B. 
Wolman (ed.), Handbook of Family and Marital Therapy. New York: Plenum Press,
1983, pp. 421-449.


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ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 7




35.      Kolodny, R.C., and Kolodny, N.J., Bratter, T.E., and Deep, C.A.  How To
Survive Your Adolescent's Adolescence. Boston: Little, Brown, 1984 (Subsequently
published in Spanish edition; published in trade paperback, 1985.)

36.      Kolodny, R.C.  The clinical management of sexual problems in substance 
abusers. In T.E. Bratter and G. Forrest (eds.), Current Management of Alcoholism
and Substance Abuse. New York; Free Press, 1985, pp. 594-622.

37.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. Human Sexuality (2nd 
edition.) Boston: Little, Brown, 1985.

38.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. Masters and Johnson on 
Sex and Human Loving. Boston: Little, Brown, 1986 (Book of the Month Club
Featured Alternate Selection; Subsequently published in Spanish, French,
Italian, German, Portuguese, Hebrew, Danish, Japanese, Russian and Dutch
editions; published in trade paperback, 1987.)

39.      Kolodny, N.J., Kolodny, R.C., and Bratter, T.E. Smart Choices.  Boston:
Little, Brown, 1986. (Subsequently published in German and Spanish editions.)

40.      Kolodny, R.C.  Medical and psychiatric perspectives on a "healthy 
sexuality." In E.E. Shelp (ed.), Sexuality and Medicine, Volume I. Dordrecht,
Holland: D. Reidel Publishing Co., 1987, pp.3-16.

41.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. Human Sexuality (3rd 
edition). Boston: Scott-Foresmann/Little, Brown, 1988.

42.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. CRISIS:Heterosexual 
Behavior in the Age of AIDS. New York: Grove Press, 1988. (Book of the Month
Club Alternate Selection; excerpted in a Newsweek cover story; subsequently
published in French, German, Spanish, Dutch, Japanese, and Italian editions.)

43.      Kolodny, R.C., Masters, W.H., and Johnson, V.E.  New directions in the 
AIDS crisis: the heterosexual community. Medical Aspects of Human Sexuality 22
(4): 78-89, 1988.

44.      Masters, W.H. Johnson, V.E., and Kolodny, R.C. Human Sexuality (4th 
edition) New York: HarperCollins, 1992.

45.      Kolodny, R.C. "Foreword" to The Practical Encyclopedia of Sex and 
Health, by Stefan Bechtel. PA: Rodale Press, 1993.

46.      Masters, W.H., Johnson, V.E., and Kolodny, R.C. Biological Foundations 
of Human Sexuality. New York: HaperCollins, 1993.

47.      Masters, W.h. Johnson, V.E., and Kolodny, R.C. Heterosexuality. New 
York: HarperCollins, 1994. (Subsequently published in trade paperback, 1995;
also published in French, Italian, German, Spanish and Japanese editions.)

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ROBERT C. KOLODNY, M.D. CURRICULUM VITAE
Page 8




48.      Masters, W.H., Johnson, V.E. and Kolodny, R.C. Human Sexuality (5th 
edition). New York: HarperCollins, 1995.


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