SENETEK PLC /ENG/
NT 10-K, 1999-03-31
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549
                                        
                                  FORM 12b-25

                                           Commission File Number  33-8072

                          NOTIFICATION OF LATE FILING

   (Check One):  [X] Form 10-K   [ ] Form 11-K  [ ] Form 20-F  [ ] Form 10-Q

[ ] Form N-SAR

    For Period Ended:  December 31, 1998
                      --------------------------------------------------------

[ ] Transition Report on Form 10-K       [ ] Transition Report on Form 10-Q

[ ] Transition Report on Form 20-F       [ ] Transition Report on Form N-SAR

[ ] Transition Report on Form 11-K

    For the Transition Period Ended:
                                     -----------------------------------------

     Read attached instruction sheet before preparing form. Please print or 
type.

     Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.

     If the notification relates to a portion of the filing checked above,
identify the item(s) to which the notification relates:

- ------------------------------------------------------------------------------

- ------------------------------------------------------------------------------

                                     PART I
                             REGISTRANT INFORMATION


Full Name of Registrant  Senetek PLC
                        ------------------------------------------------------
          
Former Name if Applicable

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Address of Principal Executive Office (Street and Number)

  23 Palace Street
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City, State and Zip Code  London, SW1E 5HW United Kingdom
                         -----------------------------------------------------


                                    PART II
                             RULE 12b-25(b) AND (c)

     If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rules 12b-25(b), the
following should be completed.  (Check box if appropriate)

        (a)    The reasons described in reasonable detail in Part III of this
               form could not be eliminated without unreasonable effort or
               expense;
              
[X]     (b)    The subject annual report, semi-annual report, transition report
               on Form 10-K, Form 20-F, 11-K or Form N-SAR, or portion thereof
               will be filed on or before the 15th calendar day following the
               prescribed due date, or the subject quarterly report of
               transition report on Form 10-Q, or portion thereof will be filed
               on or before the fifth calendar day following the prescribed due
               date; and
              
        (c)    The accountant's statement or other exhibit required by Rule
               12b-25(c) has been attached if applicable.


                                    PART III
                                   NARRATIVE

     State below in reasonable detail the reasons why the Form 10-K, 11-K, 20-F,
10-Q, N-SAR, or the transition report portion thereof could not be filed
within the prescribed time period.  (Attach extra sheets if needed.)

     The Registrant is unable to file its Form 10-K for the fiscal year ended 
December 31, 1998 within the prescribed time period. On February 23, 1999, the 
Registrant engaged a new auditing firm, BDO Stoy Hayward and thus, Registrant 
will require additional time to complete the preparation of its financial 
statements for the fiscal year.
<PAGE>   2

                                    PART IV
                               OTHER INFORMATION

     (1)  Name and telephone number of person to contact in regard
to this notification.

      Frank J. Massino                      (707)             226-3900         
- --------------------------------------------------------------------------------
            (Name)                         (Area Code)      (Telephone Number)

     (2) Have all other periodic reports required under Section 13 or 15(d) of
the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act
of 1940 during the preceding 12 months or for such shorter period that the
registrant was required to file such report(s) been filed?  If answer is no,
identify report(s).

                                                                 [X] Yes [ ] No
                                                                  

     (3) Is it anticipated that any significant change in results of operations
from the corresponding period for the last fiscal year will be reflected by the
earnings statements to be included in the subject report of portion thereof?

                                                                 [ ] Yes [X] No

     If so, attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results cannot be made.

- ------------------------------------------------------------------------------

                                  Senetek PLC
- ------------------------------------------------------------------------------
                  (Name of Registrant as Specified in Charter)

Has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.

Date    March 30, 1999                  By /s/ Frank J. Massino   
     ---------------------------         -------------------------------------
                                         Frank J. Massino
                                         President and Chief Executive Officer
                                         


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