<PAGE> 1
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
(RULE 13d-102)
(AMENDMENT NO. 12)(1)
INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
TO RULES 13d-1(b) AND (c) AND AMENDMENTS THERETO FILED
PURSUANT TO 13d-2(b)
ADVANCED MAGNETICS, INC.
- --------------------------------------------------------------------------------
(Name of Issuer)
COMMON STOCK
- --------------------------------------------------------------------------------
(Title of Class of Securities)
00753P 10 3
-------------------------------------
(CUSIP Number)
- --------
(1) The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
<PAGE> 2
- ------------------------- -------------------------
CUSIP NO. 00753P 10 3 13G Page 2 of 5 Pages
-----------
- ------------------------- -------------------------
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Jerome Goldstein
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
No Change
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
657,272
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY 42,000
OWNED BY
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON 657,272
WITH
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
42,000
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
699,272
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN [X]
SHARES*
See Item 4(a)
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
10.4%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
No Change
- --------------------------------------------------------------------------------
*SEE INSTRUCTION BEFORE FILLING OUT!
<PAGE> 3
ITEM 1(a). NAME OF ISSUER:
Advanced Magnetics, Inc.
ITEM 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
61 Mooney Street
Cambridge, MA 02138
ITEM 2(a). NAME OF PERSON FILING:
Jerome Goldstein
ITEM 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:
c/o Advanced Magnetics, Inc.
61 Mooney Street
Cambridge, MA 02138
ITEM 2(c). CITIZENSHIP:
United States
ITEM 2(d). TITLE OF CLASS OF SECURITIES:
Common Stock, $.01 Par Value
ITEM 2(e). CUSIP NUMBER
00753P 10 3
ITEM 3. STATUS IF FILED PURSUANT TO RULES 13d-1(b) OR 13d-2(b):
Inapplicable
ITEM 4. OWNERSHIP:
(a) Amount Beneficially Owned:
699,272. This amount does not include 662,937 shares
owned by spouse as to which shares beneficial ownership
is disclaimed. This amount includes 11,250 shares
issuable to Mr. Goldstein pursuant to options
exercisable or exercisable within 60 days from December
31, 1997.
Page 3 of 5 pages
<PAGE> 4
(b) Percent of Class: 10.4% (based on 6,733,276 shares of
Common Stock reported by the Company's transfer agent as
outstanding at the close of business on December 31,
1997 and 11,250 shares issuable to Mr. Goldstein
pursuant to options exercisable within 60 days from
December 31, 1997).
(c) Number of Shares as to which such person has:
(i) sole power to vote or direct the vote 657,272.
(ii) shared power to vote or to direct the vote
42,000.
(iii) sole power to dispose or to direct the
disposition of 657,272.
(iv) shared power to dispose or to direct the
disposition of 42,000.
ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:
Inapplicable.
ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:
Inapplicable.
ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT COMPANY:
Inapplicable.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:
Inapplicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP:
Inapplicable.
ITEM 10. CERTIFICATION:
Inapplicable.
Page 4 of 5 pages
<PAGE> 5
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
February 4, 1998
---------------------------------------
Date
/s/ Jerome Goldstein
---------------------------------------
Signature
Jerome Goldstein/
Chairman of the Board,
Chief Executive Officer and Treasurer
---------------------------------------
Name/Title
Page 5 of 5 pages