EPITOPE INC/OR/
8-A12G, 1997-12-24
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                -----------------

                                    FORM 8-A

           FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT
         TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934

                                  EPITOPE, INC.

             (Exact name of registrant as specified in its charter)



              Oregon                                      93-0779127

(State of incorporation or organization)    (I.R.S. Employer Identification No.)


 8505 S.W. Creekside, Beaverton, Oregon                     97008

(Address of principal executive offices)                 (Zip Code)



If this Form relates to the  registration  of a class of debt  securities and is
effective upon filing pursuant to General Instruction A(c)(1),  please check the
following box [ ]

If this Form relates to the registration of a class of debt securities and is to
become effective of a concurrent registration statement under the Securities Act
of 1933 pursuant to General Instruction A(c)(2),  please check the following box
[ ]


Securities to be registered pursuant to Section 12(b) of the Act:


     Title of each class                       Name of each exchange on which
     to be so registered                       each class is to be registered

            None                                            None

Securities to be registered pursuant to Section 12(g) of the Act:

                         Preferred Stock Purchase Rights

                                (Title of class)



<PAGE>



Item 1.        Description of Registrant's Securities to be Registered.

               Pursuant  to  resolutions  adopted by the Board of  Directors  of
Epitope, Inc. ("the Company"), the Company issued a dividend distribution of one
Right for each  outstanding  share of common  stock,  no par value (the  "Common
Stock"),  of the Company to the  shareholders of record at the close of business
on December 26, 1997 (the "Record  Date").  Each Right  entitles the  registered
holder  to  purchase  from the  Company  1/1,000  of a share of  Series A Junior
Participating  Cumulative  Preferred  Stock,  without par value (the  "Preferred
Shares"),  at a price  of $60 per  share  (the  "Purchase  Price"),  subject  to
adjustment.  The  description  and terms of the Rights are set forth in a Rights
Agreement dated December 15, 1997 (the "Rights Agreement"),  between the Company
and  ChaseMellon  Shareholder  Services,  L.L.C.,  as Rights  Agent (the "Rights
Agent").

               Initially,  the  Rights  will be  attached  to all  Common  Stock
certificates representing shares then outstanding,  and no separate certificates
evidencing Rights ("Right Certificates") will be distributed.  Until the earlier
of the close of business on (i) the tenth day after a public announcement that a
person or group of affiliated or associated  persons  (other than the Company or
its employee benefit plans) (an "Acquiring Person"),  acquired,  or obtained the
right to acquire,  beneficial ownership of 15 percent or more of the outstanding
shares of Common  Stock and (ii) the tenth  business  day (or such later date as
may be determined by the Board of Directors)  after the  commencement of (or the
announcement  of an  intention  to make) a tender  offer or  exchange  offer the
consummation  of which would result in the  beneficial  ownership by a person or
group of 15  percent  or more of the  outstanding  shares of Common  Stock,  the
Rights will be evidenced,  with respect to any of the Common Stock  certificates
outstanding  as of the Record  Date,  by such  Common  Stock  certificates.  The
earlier of the dates  described  in clauses (i) and (ii) above is referred to as
the "Distribution Date."

               Until the Distribution  Date, the Rights will be transferred with
and only with the Common Stock. As long as the Rights are attached to the Common
Stock,  the  Company  will issue one Right with each share of Common  Stock that
becomes  outstanding so that all outstanding  shares will have attached  Rights.
Until the  Distribution  Date (or the earlier  redemption  or  expiration of the
Rights),  (i)  Common  Stock  certificates  issued  after the  Record  Date upon
transfer or new issuance of Common Stock will contain a legend incorporating the
Rights  Agreement  by  reference  and (ii) the  surrender  for  transfer  of any
certificates  evidencing  Common Stock will also  constitute the transfer of the
Rights associated with the Common Stock represented by such certificate. As soon
as practicable  following the  Distribution  Date,  Right  Certificates  will be
mailed to holders of record of the Common  Stock as of the close of  business on
the Distribution Date and such separate Right  Certificates  alone will evidence
the Rights.

               The Rights are not exercisable  until the Distribution  Date. The
Rights will expire (i) at the close of business on December 26, 2007,  (ii) upon
exchange by the



                                      - 2 -

<PAGE>



Company for Common Stock as described  below,  or (iii) upon  redemption  by the
Company as described below, whichever is earliest.

               In the event that any person becomes an Acquiring Person,  proper
provision  shall be made so that each  holder  of a Right  (except  as  provided
below) will  thereafter  have the right to receive upon  exercise that number of
shares of Common  Stock of the  Company  having a market  value of two times the
exercise  price of the Right.  No such  adjustment  to the Rights  will be made,
however,  if a person  becomes  an  Acquiring  Person  pursuant  to a tender  or
exchange offer for all outstanding Common Stock at a price and on terms that are
fair to and otherwise in the best interests of the Company and its shareholders,
as determined by a majority of the Board of Directors in the manner described in
the Rights Agreement (a "Qualifying Offer").

               In the event  that,  at any time  after  any  person  becomes  an
Acquiring  Person,  the  Company  is  acquired  in a merger  or  other  business
combination  transaction (other than a transaction made pursuant to a Qualifying
Offer and meeting certain other requirements described in the Rights Agreement),
or more than 50 percent of its assets or earning power is sold, proper provision
shall be made so that each  holder of a Right  (except as  provided  below) will
thereafter  have the right to receive,  upon the  exercise  at the then  current
exercise  price of the  Right,  that  number of  shares  of common  stock of the
acquiring or surviving  company  having a market value of two times the exercise
price of the Right.

               Following the  occurrence  of any of the events  described in the
preceding  two  paragraphs  (other  than those  events  relating  to  Qualifying
Offers),  any Rights that are or (under certain  circumstances  specified in the
Rights  Agreement)  were,  beneficially  owned  by any  Acquiring  Person  shall
immediately become null and void.

               The Purchase Price payable, and the number of Preferred Shares or
other securities or property  issuable,  upon exercise of the Rights are subject
to adjustment from time to time to prevent dilution.

               The Company is not required to issue fractional  Preferred Shares
other than  fractions in multiples of 1/1,000 of a share.  In lieu of fractional
Preferred Shares, an adjustment in cash may be made based on the market price of
the Preferred Shares on the last trading date prior to the date of exercise.

               At any time  prior to the tenth day  following  the first  public
announcement of the existence of an Acquiring Person, the Company may redeem the
Rights in whole,  but not in part, at a price of $.01 per Right (the "Redemption
Price").  Immediately  upon the action of the Board of  Directors  ordering  the
redemption  of the Rights (or at such time and date  thereafter  as the Board of
Directors may specify),  the right to exercise the Rights will terminate and the
only right of the holders of Rights will be to receive the Redemption Price.



                                      - 3 -

<PAGE>



               At any time after a person becomes an Acquiring  Person and prior
to the  acquisition  by  such  Acquiring  Person  of 50  percent  or more of the
outstanding  shares of Common Stock,  the Company may exchange the Rights (other
than Rights  beneficially  owned by such Acquiring  Person which became null and
void), in whole or in part, for Common Stock at the rate of one share per Right,
subject to adjustment.

               Until a Right is exercised,  the holder  thereof,  as such,  will
have no rights as a shareholder of the Company,  including,  without limitation,
the right to vote or to receive dividends.

               Prior to the time a  person  becomes  an  Acquiring  Person,  the
provisions  of the Rights  Agreement  may be amended in any manner.  Thereafter,
with certain  exceptions,  the provisions of the Rights Agreement may be amended
in order to cure any ambiguity,  defect or inconsistency,  to make changes which
do not  adversely  affect the  interests  of holders  of Rights  (excluding  the
interest of any  Acquiring  Person),  or to shorten or lengthen  any time period
under the Rights Agreement;  provided,  however, that no amendment to adjust the
time period  governing  redemption  shall be made at such time as the Rights are
not redeemable.

               The Rights have certain  anti-takeover  effects.  The Rights will
cause  substantial  dilution  to a person or group of persons  that  attempts to
acquire  the  Company,  other  than in a  transaction  approved  by the Board of
Directors  of the Company at a time when the Rights are  redeemable.  The Rights
should not interfere with any acquisition,  merger or other business combination
approved by the Board of Directors at a time when the Rights are redeemable.

               The Rights Agreement and the Restated  Articles of Incorporation,
as  amended,  setting  forth  the  terms of the  Preferred  Shares  are filed as
exhibits to this report and are incorporated herein by reference.  The foregoing
description  of the Rights does not purport to be complete  and is  qualified in
its entirety by reference to the Rights  Agreement and the Restated  Articles of
Incorporation, as amended.



                                      - 4 -

<PAGE>



Item 2.        EXHIBITS.

               The  exhibits  filed  herewith  are listed in the  exhibit  index
following the signature page of this registration.



                                      - 5 -

<PAGE>



                                   SIGNATURES


               Pursuant  to the  requirements  of Section  12 of the  Securities
Exchange Act of 1934,  the registrant  has duly caused this  registration  to be
signed on its behalf by the undersigned, thereto duly authorized.

                                             EPITOPE, INC.



Dated:  December 23, 1997                    By:  /s/ Charles E. Bergeron
                                                  Charles E. Bergeron
                                                  Vice President of Operations



<PAGE>


                                  EXHIBIT INDEX


3.             Restated Articles of Incorporation, as amended, of Epitope, Inc.


4.1            Rights Agreement dated as of December 15, 1997,  between Epitope,
               Inc., and ChaseMellon Shareholder Services, L.L.C.

4.2            Specimen of certificate for the Common Stock of Epitope, Inc., to
               be used to evidence  shares of such stock issued after the Record
               Date and until the  Distribution  Date (as such dates are defined
               in Item 1 above).



                       RESTATED ARTICLES OF INCORPORATION
                                       OF
                                  EPITOPE, INC.


                                    ARTICLE I

         The name of this  corporation is Epitope,  Inc., and its duration shall
be perpetual.

                                   ARTICLE II

         The purposes for which this corporation is organized:

         1. To own,  conduct,  operate,  maintain and carry on the business of a
clinical,  research and testing  medical  laboratory  engaging in  immunological
monitoring  procedures,  procedures  relating  to  the  definition  of  specific
genetically inherited factors, consulting work, and related activities.

         2. To buy, sell, distribute,  exchange,  manufacture,  design, develop,
promote,  license,  franchise,  repair,  remodel,  recondition,  import, export,
lease, mortgage,  pledge and otherwise deal in and with all kinds and classes of
merchandise,  equipment  and  products,  and in  connection  therewith to act as
distributors,  wholesalers,  retailers,  commission merchants, jobbers, factors,
agents and factory representatives.

         3. To own, buy, sell, lease, mortgage, pledge and otherwise deal in and
with personal property and real property of every kind, nature and description.

         4. To enter into  partnerships,  joint ventures or any  arrangement for
the sharing of profits with any person,  firm or  corporation,  and to engage in
any business or  transaction  in which this  corporation  would be authorized to
engage in alone.

         5. To borrow  money in any amounts and on any terms  authorized  by its
Board of Directors.

         6. To endorse,  guarantee  and secure the payment and  satisfaction  of
contracts,  negotiable  instruments,  obligations or evidence of indebtedness of
other persons, firms or corporations.

         7. To lend money to parties having dealings with this corporation,  and
to assist in support  financially or otherwise with any other business,  firm or
corporation.

         8. To engage in  business  in the  state of  Oregon  and in such  other
states and foreign countries as may be authorized by its Board of Directors.



                                      - 1 -

<PAGE>



         9. To engage in any  lawful  activity  for  which  corporations  may be
organized under Chapter 60 of the Oregon Revised Statutes.

                                   ARTICLE III

         The corporation may indemnify any director,  officer, employee or agent
or former director, officer, employee or agent of the corporation, or any person
who may have served at its request as a director,  officer, employee or agent of
another corporation in which it owns shares of capital stock or of which it is a
creditor,  against expenses and liability  actually and necessarily  incurred by
him in  connection  with any action,  suit or  proceeding  in which he is made a
party by reason of being or having  been such  director,  officer,  employee  or
agent,  except in relation to matters as to which  indemnification is prohibited
by the Oregon Business  Corporation Act; but such  indemnification  shall not be
deemed exclusive of any other rights to which such director,  officer,  employee
or agent may be entitled, under any bylaw, agreement, general or specific action
of the Board of Directors, vote of shareholders or otherwise.

                                   ARTICLE IV

         No  director  of the  corporation  shall be  personally  liable  to the
corporation or its shareholders for monetary damages by reason of his conduct as
director  except to the extent that such  elimination of liability is prohibited
by the Oregon  Business  Corporation  Act. No amendment  to the Oregon  Business
Corporation Act that further limits the acts or omissions for which  elimination
of liability is permitted  shall affect the  liability of a director for any act
or omission which occurs prior to the effective date of such amendment.

                                    ARTICLE V

                  A. The aggregate number of shares of authorized  capital stock
         which the  corporation  shall have  authority to issue shall be in such
         amounts and divided into classes as follows:

            Title of Class                              No. of Shares

            Preferred Stock, no par                      1,000,000
                     value

            Common Stock, no par                        30,000,000
                     value

                  B. The  preferences,  limitations,  and relative rights of the
         shares of each class shall be as follows:



                                      - 2 -

<PAGE>



                           1.  Preferred Stock.

                                    a.  Division  into  Series.   The  Board  of
                           Directors   shall  have   authority   to  divide  the
                           Preferred  Stock into as many  series as the Board of
                           Directors shall from time to time  determine,  and to
                           issue the Preferred  Stock in such series.  The Board
                           of  Directors  shall  determine  the number of shares
                           comprising  each  series,  which  number may,  unless
                           otherwise  provided  by the  Board  of  Directors  in
                           creating such series,  be increased or decreased from
                           time to time by  action  of the  Board of  Directors.
                           Each series shall be so designated as to  distinguish
                           the  shares  thereof  from the  shares  of all  other
                           series.

                                    b.   Authority  of  Board  of  Directors  to
                           Determine  Preferences,   Limitations,  and  Relative
                           Rights.  The Board of Directors  shall have authority
                           to determine,  except as otherwise prescribed in this
                           Article V or by law,  the  preferences,  limitations,
                           and relative rights,  including voting rights, of the
                           shares of Preferred  Stock before the issuance of any
                           shares of such class or the preferences, limitations,
                           and relative rights,  including voting rights, of the
                           shares of any series of  Preferred  Stock  before the
                           issuance of any shares of such series.  All shares of
                           any such series shall have preferences,  limitations,
                           and  relative   rights,   including   voting  rights,
                           identical  with  those  of other  shares  of the same
                           series and, except to the extent  otherwise  provided
                           in the description of such series,  of those of other
                           series of the Preferred Stock.

                           2.  Common Stock.

                           Subject to the preferences, limitations, and relative
                  rights of the  Preferred  Stock,  or any series  thereof,  the
                  holders of Common Stock shall have all rights of shareholders,
                  including,  without limitation, (i) unlimited voting rights on
                  all  corporate  matters  on the  basis of one vote per  share,
                  except as such voting  rights may be limited or required to be
                  shared  together  with another  class or series as provided by
                  law,  and (ii) the  right to  receive  the net  assets  of the
                  corporation upon dissolution.

                           3.  Denial of Preemptive Rights.

                           No  shareholder  shall have any  preemptive  right to
                  acquire  additional  shares of this  corporation,  whether  of
                  shares  originally   authorized  or  other  shares  which  may
                  subsequently be authorized.



                                      - 3 -

<PAGE>



                  C. A series of the Preferred Stock hereby is created,  and the
         designation  and amount thereof and the  preferences,  limitations  and
         relative rights thereof are determined to be as follows:

                           1.  Designation and Amount.

                           The  shares of such  series  shall be  designated  as
                  Series A Junior  Participating  Cumulative Preferred Stock, no
                  par value, and the number of shares  constituting  such series
                  shall be 30,000. Such series is hereinafter referred to as the
                  "Series A Preferred Stock."

                           2.  Dividends and Distributions.

                                    a.  The   holders  of  shares  of  Series  A
                           Preferred  Stock,  in  preference  to the  holders of
                           Common Stock, no par value (the "Common  Stock"),  of
                           the  Corporation  and of any other junior stock which
                           may be  outstanding,  shall be  entitled  to receive,
                           when,  as and if declared  by the Board of  Directors
                           out of funds legally  available for the purpose,  (i)
                           quarterly  dividends payable in cash on the first day
                           of March,  June,  September and December in each year
                           (each  such  date  being  referred  to  herein  as  a
                           "Quarterly Dividend Payment Date"), commencing on the
                           first Quarterly Dividend Payment Date after the first
                           issuance  of a share or fraction of a share of Series
                           A Preferred Stock, in an amount per share (rounded to
                           the  nearest  cent) equal to the greater of (a) $1.00
                           per  share,  or  (b)  subject  to the  provision  for
                           adjustment  hereinafter  set forth,  1,000  times the
                           aggregate  per  share  amount  of all cash  dividends
                           declared on the Common  Stock  since the  immediately
                           preceding  Quarterly  Dividend  Payment Date or, with
                           respect to the first Quarterly Dividend Payment Date,
                           since the first  issuance of any share or fraction of
                           a share of Series A Preferred Stock, and (ii) subject
                           to  the  provision  for  adjustment  hereinafter  set
                           forth,  quarterly  distributions (payable in kind) on
                           each Quarterly Dividend Payment Date in an amount per
                           share  equal to 1,000 times the  aggregate  per share
                           amount   of   all   noncash    dividends   or   other
                           distributions  (other  than  a  dividend  payable  in
                           shares  of  Common  Stock  or a  subdivision  of  the
                           outstanding    shares    of    Common    Stock,    by
                           reclassification  or  otherwise),   declared  on  the
                           Common   Stock   since  the   immediately   preceding
                           Quarterly  Dividend  Payment Date, or with respect to
                           the first Quarterly  Dividend  Payment Date since the
                           first issuance of any share or fraction of a share of
                           Series  A   Preferred   Stock.   In  the   event  the
                           Corporation  shall at any time after October 21, 1997
                           (the "Rights Declaration  Date"),  declare or pay any
                           dividend on Common Stock  payable in shares of Common
                           Stock, or effect a subdivision or



                                      - 4 -

<PAGE>



                           combination  or   consolidation  of  the  outstanding
                           shares  of  Common  Stock  (by   reclassification  or
                           otherwise)  into a greater or lesser number of shares
                           of Common Stock, then in each such case the amount to
                           which  holders of shares of Series A Preferred  Stock
                           are  entitled  under  clauses  (i)(b)  or (ii) of the
                           preceding  sentence  shall be adjusted by multiplying
                           such amount by a fraction  the  numerator of which is
                           the  number of shares  of  Common  Stock  outstanding
                           immediately  after such event and the  denominator of
                           which is the  number of shares of Common  Stock  that
                           were outstanding immediately prior to such event.

                                    b. The Corporation shall declare a mandatory
                           dividend  or  distribution  on the Series A Preferred
                           Stock as provided in Section 2.a immediately after it
                           declares a  dividend  or  distribution  on the Common
                           Stock  (other  than a  dividend  payable in shares of
                           Common  Stock);   provided  that,  in  the  event  no
                           dividend or distribution  shall have been declared on
                           the  Common  Stock  during  the  period  between  any
                           Quarterly   Dividend   Payment   Date  and  the  next
                           subsequent   Quarterly   Dividend   Payment  Date,  a
                           mandatory dividend of $1.00 per share on the Series A
                           Preferred Stock shall nevertheless be payable on such
                           subsequent Quarterly Dividend Payment Date.

                                    c.  Dividends  shall  begin to accrue and be
                           cumulative   on   outstanding   shares  of  Series  A
                           Preferred Stock from the Quarterly  Dividend  Payment
                           Date next  preceding the date of issue of such shares
                           of Series A Preferred Stock, unless the date of issue
                           of such  shares is prior to the  record  date for the
                           first Quarterly  Dividend Payment Date, in which case
                           dividends  on such shares  shall begin to accrue from
                           the date of issue of such shares,  or unless the date
                           of issue is a Quarterly Dividend Payment Date or is a
                           date after the record date for the  determination  of
                           holders  of  shares  of  Series  A  Preferred   Stock
                           entitled to receive a quarterly  dividend  and before
                           such  Quarterly  Dividend  Payment Date, in either of
                           which events such dividends shall begin to accrue and
                           be cumulative  from such Quarterly  Dividend  Payment
                           Date. Accrued but unpaid dividends shall cumulate but
                           shall not bear interest. Dividends paid on the shares
                           of Series A  Preferred  Stock in an amount  less than
                           the  total  amount  of  such  dividends  at the  time
                           accrued and payable on such shares shall be allocated
                           pro rata on a  share-by-share  basis  among  all such
                           shares  at  the  time   outstanding.   The  Board  of
                           Directors may fix a record date for the determination
                           of  holders  of shares of  Series A  Preferred  Stock
                           entitled   to  receive   payment  of  a  dividend  or
                           distribution declared thereon, which



                                      - 5 -

<PAGE>



                           record  date  shall be not more than 45 days prior to
                           the date fixed for the payment thereof.

                           3.  Voting Rights.

                           The  holders  of shares of Series A  Preferred  Stock
                  shall have the following voting rights:

                                    a. Subject to the provision  for  adjustment
                           hereinafter  set  forth,   each  share  of  Series  A
                           Preferred  Stock shall entitle the holder  thereof to
                           1,000 votes (and each  1/1,000 of a share of Series A
                           Preferred  Stock shall entitle the holder  thereof to
                           one vote) on all matters  submitted  to a vote of the
                           shareholders  of the  Corporation.  In the  event the
                           Corporation  shall  at  any  time  after  the  Rights
                           Declaration  Date  declare  or pay  any  dividend  on
                           Common Stock  payable in shares of Common  Stock,  or
                           effect a subdivision or combination or  consolidation
                           of  the  outstanding   shares  of  Common  Stock  (by
                           reclassification  or  otherwise)  into a  greater  or
                           lesser number of shares of Common Stock, then in each
                           such  case the  number  of votes  per  share to which
                           holders  of shares of Series A  Preferred  Stock were
                           entitled  immediately  prior to such  event  shall be
                           adjusted  by  multiplying  such number by a fraction,
                           the  numerator  of which is the  number  of shares of
                           Common Stock outstanding immediately after such event
                           and the  denominator of which is the number of shares
                           of Common  Stock  that were  outstanding  immediately
                           prior to such event.

                                    b.  Except  as  otherwise  provided  in  the
                           Articles of  Incorporation  or herein or by law,  the
                           holders of shares of Series A Preferred Stock and the
                           holders of shares of Common Stock shall vote together
                           as one class on all  matters  submitted  to a vote of
                           the shareholders of the Corporation.

                                    c.  Except as set forth  herein,  holders of
                           Series A Preferred Stock shall have no special voting
                           rights  and  their  consent  shall  not  be  required
                           (except to the extent  they are  entitled  to vote as
                           set forth in the Articles of  Incorporation or herein
                           or by law) for taking any corporate action.

                           4.  Certain Restrictions.

                                    a.  Whenever  quarterly  dividends  or other
                           dividends  or  distributions  payable on the Series A
                           Preferred  Stock  as  provided  in  Section  2 are in
                           arrears,  thereafter and until all accrued and unpaid
                           dividends and distributions, whether or not declared,
                           on



                                      - 6 -

<PAGE>



                           shares of Series A Preferred Stock  outstanding shall
                           have been paid in full, the Corporation shall not:

                                            (i) declare or pay  dividends  on or
                                    make any other  distributions  on any shares
                                    of  stock  ranking   junior  (either  as  to
                                    dividends or upon  liquidation,  dissolution
                                    or  winding  up) to the  Series A  Preferred
                                    Stock;

                                            (ii) declare or pay  dividends on or
                                    make any other  distributions  on any shares
                                    of stock  ranking on a parity  (either as to
                                    dividends or upon  liquidation,  dissolution
                                    or winding  up) with the Series A  Preferred
                                    Stock,  except dividends paid ratably on the
                                    Series A Preferred Stock and all such parity
                                    stock on which  dividends  are payable or in
                                    arrears in  proportion  to the total amounts
                                    to which the  holders of all such shares are
                                    then entitled;

                                            (iii)    redeem   or   purchase   or
                                    otherwise acquire for  consideration  shares
                                    of any stock  ranking  junior  (either as to
                                    dividends or upon  liquidation,  dissolution
                                    or  winding  up) to the  Series A  Preferred
                                    Stock,  provided that the Corporation may at
                                    any  time  redeem,   purchase  or  otherwise
                                    acquire  shares of any such junior  stock in
                                    exchange  for  shares  of any  stock  of the
                                    Corporation  ranking  junior  (either  as to
                                    dividends or upon  dissolution,  liquidation
                                    or  winding  up) to the  Series A  Preferred
                                    Stock; or

                                            (iv)  purchase or otherwise  acquire
                                    for  consideration  any  shares  of Series A
                                    Preferred  Stock,  or  any  share  of  stock
                                    ranking  on  a  parity  with  the  Series  A
                                    Preferred Stock, except in accordance with a
                                    purchase   offer   made  in  writing  or  by
                                    publication  (as  determined by the Board of
                                    Directors)  to all  holders  of such  shares
                                    upon such  terms as the Board of  Directors,
                                    after consideration of the respective annual
                                    dividend rates and other relative rights and
                                    preferences  of the  respective  series  and
                                    classes,  shall determine in good faith will
                                    result in fair and equitable treatment among
                                    the respective series or classes.

                                    b. The  Corporation  shall  not  permit  any
                           subsidiary   of  the   Corporation   to  purchase  or
                           otherwise  acquire  for  consideration  any shares of
                           stock  of  the  Corporation  unless  the  Corporation
                           could,



                                      - 7 -

<PAGE>



                           under Section 4.a, purchase or otherwise acquire such
                           shares at such time and in such manner.

                           5.  Reacquired Shares.

                           Any shares of Series A Preferred  Stock  purchased or
                  otherwise acquired by the Corporation in any manner whatsoever
                  shall be retired and canceled  promptly after the  acquisition
                  thereof.  The  Corporation  shall  take all such  action as is
                  necessary   so  that  all  such   shares   shall  after  their
                  cancellation   become   authorized  but  unissued   shares  of
                  Preferred Stock,  without designation as to series, and may be
                  reissued  as part of a new  series  of  Preferred  Stock to be
                  created  by  resolution  or   resolutions   of  the  Board  of
                  Directors,  subject  to the  conditions  and  restrictions  on
                  issuance set forth herein.

                           6.  Liquidation, Dissolution or Winding Up.

                           Upon any  liquidation,  dissolution  or winding up of
                  the  Corporation,  no  distribution  shall  be made (A) to the
                  holders  of  shares  of stock  ranking  junior  (either  as to
                  dividends or upon  liquidation,  dissolution or winding up) to
                  the  Series A  Preferred  Stock  unless,  prior  thereto,  the
                  holders  of shares  of Series A  Preferred  Stock  shall  have
                  received  the  higher of (i) $1.00 per  share,  plus an amount
                  equal  to  accrued  and  unpaid  dividends  and  distributions
                  thereon, whether or not declared, to the date of such payment,
                  or  (ii)  an  aggregate  amount  per  share,  subject  to  the
                  provision for adjustment hereinafter set forth, equal to 1,000
                  times  the  aggregate  amount to be  distributed  per share to
                  holders of Common Stock;  nor shall any  distribution  be made
                  (B) to the holders of stock ranking on a parity  (either as to
                  dividends or upon liquidation, dissolution or winding up) with
                  the  Series  A  Preferred  Stock,  except  distributions  made
                  ratably  on the  Series A  Preferred  Stock and all other such
                  parity stock in  proportion  to the total amounts to which the
                  holders of all such shares are entitled upon such liquidation,
                  dissolution or winding up. In the event the Corporation  shall
                  at any  time  declare  or pay any  dividend  on  Common  Stock
                  payable in shares of Common Stock,  or effect a subdivision or
                  combination  or  consolidation  of the  outstanding  shares of
                  Common Stock (by reclassification or otherwise) into a greater
                  or lesser number of shares of Common Stock,  then in each such
                  case the aggregate amount to which holders of shares of Series
                  A Preferred  Stock are entitled  under  clause  (A)(ii) of the
                  preceding  sentence  shall be  adjusted  by  multiplying  such
                  amount by a fraction  the  numerator of which is the number of
                  shares of Common  Stock  outstanding  immediately  after  such
                  event and the  denominator of which is the number of shares of
                  Common Stock that were outstanding  immediately  prior to such
                  event.



                                      - 8 -

<PAGE>



                           7.  Consolidation, Merger, etc.

                           In  case  the   Corporation   shall  enter  into  any
                  consolidation, merger, statutory plan of exchange, combination
                  or other  transaction  in which the shares of Common Stock are
                  exchanged for or changed into other stock or securities,  cash
                  and/or any other property,  or otherwise changed,  then in any
                  such case the shares of Series A Preferred  Stock shall at the
                  same time be  similarly  exchanged or changed in an amount per
                  share (subject to the provision for adjustment hereinafter set
                  forth)  equal to 1,000  times the  aggregate  amount of stock,
                  securities,  cash and/or any other property (payable in kind),
                  as the case may be,  into  which or for  which  each  share of
                  Common  Stock  is  changed  or  exchanged.  In the  event  the
                  Corporation  shall at any time  declare or pay any dividend on
                  Common Stock  payable in shares of Common  Stock,  or effect a
                  subdivision or combination or consolidation of the outstanding
                  shares of Common Stock (by reclassification or otherwise) into
                  a greater or lesser number of shares of Common Stock,  then in
                  each such case the amount set forth in the preceding  sentence
                  with  respect to the  exchange or change of shares of Series A
                  Preferred  Stock shall be adjusted by multiplying  such amount
                  by a fraction  the  numerator of which is the number of shares
                  of Common Stock  outstanding  immediately after such event and
                  the  denominator  of which is the  number  of shares of Common
                  Stock that were outstanding immediately prior to such event.

                           8.  No Redemption.

                           The shares of Series A  Preferred  Stock shall not be
                  redeemable. Notwithstanding the foregoing, the Corporation may
                  acquire shares of Series A Preferred Stock in any other manner
                  permitted  by  law,  the  Articles  of  Incorporation  or this
                  amendment thereof.

                           9.  Rank.

                           Unless   otherwise   provided  in  the   Articles  of
                  Incorporation or an amendment thereof relating to a subsequent
                  series of  Preferred  Stock of the  Corporation,  the Series A
                  Preferred  Stock shall rank junior to all other  series of the
                  Corporation's  Preferred  Stock as to the payment of dividends
                  and the distribution of assets on liquidation,  dissolution or
                  winding up, and senior to the Common Stock of the Corporation.

                           10.  Amendment.

                           The Articles of Incorporation shall not be amended in
                  any manner which would  materially alter or change the powers,
                  preferences or special rights of the Series A Preferred  Stock
                  so as to affect them adversely



                                      - 9 -

<PAGE>



                  without  the  affirmative  vote of the  holders  of at least a
                  majority  of the  outstanding  shares  of  Series A  Preferred
                  Stock, voting separately as a class.

                           11.  Fractional Shares.

                           Series A Preferred Stock may be issued in 1/1,000s of
                  a share or other  fractions of a share which shall entitle the
                  holder, in proportion to such holder's  fractional  shares, to
                  exercise  voting  rights,  receive  dividends,  participate in
                  distributions  and to have the benefit of all other  rights of
                  holders of Series A Preferred Stock.

                                   ARTICLE VI

                  A. The number of  directors  of the  corporation  shall be not
         less than six nor more than  nine,  and  within  such  limits the exact
         number shall be fixed and  increased or decreased  from time to time by
         resolution  of the Board of Directors.  The directors  shall be divided
         into three  classes  designated  Class I, Class II and Class III,  each
         class to be as nearly equal in number as  possible.  At the 1991 annual
         meeting  of  shareholders,  directors  of all  three  classes  shall be
         elected and the term of office of Class III  directors  shall expire at
         the 1992 annual  meeting of  shareholders,  that of Class II  directors
         shall expire at the 1993 annual  meeting of  shareholders,  and that of
         Class  I  directors   shall  expire  at  the  1994  annual  meeting  of
         shareholders.  At  each  annual  meeting  of  shareholders  thereafter,
         directors  elected to succeed those  directors whose terms expire shall
         be elected to serve for three-year terms and until their successors are
         elected and qualified,  so that the term of one class of directors will
         expire each year.  When the number of directors  is changed  within the
         limits  provided  herein,  any  newly  created  directorships,  or  any
         decrease in directorships, shall be so apportioned among the classes as
         to make all  classes  as nearly  equal as  possible,  provided  that no
         decrease in the number of directors constituting the Board of Directors
         shall shorten the term of any incumbent directors.

                  B. All or any number of the directors of the  corporation  may
         be removed,  with or without cause,  only at a meeting of  shareholders
         called  expressly  for that  purpose,  by the vote of 90 percent of the
         votes then  entitled to be cast for the election of  directors.  At any
         meeting of shareholders  at which one or more directors are removed,  a
         majority  of  votes  then  entitled  to be  cast  for the  election  of
         directors may fill any vacancy created by such removal.  If any vacancy
         created by removal of a director is not filled by the  shareholders  at
         the  meeting at which the  removal is  effected,  such  vacancy  may be
         filled by a majority vote of the remaining directors.

                  C.  The  provisions  of this  Article  VI may not be  amended,
         altered,  changed,  or repealed  in any  respect  unless such action is
         approved by the



                                     - 10 -

<PAGE>


         affirmative vote of not less than 90 percent of the votes then entitled
         to be cast for election of directors.



                                     - 11 -

================================================================================


                                  EPITOPE, INC.


                                       AND


                    CHASEMELLON SHAREHOLDER SERVICES, L.L.C.
                                  RIGHTS AGENT




                                RIGHTS AGREEMENT




================================================================================



                         Dated as of December 15, 1997



<PAGE>



                                TABLE OF CONTENTS

Section                                                                     Page

1.       Certain Definitions.................................................  1

2.       Appointment of Rights Agent.........................................  4

3.       Issuance of Right Certificates......................................  4

4.       Form of Right Certificates..........................................  6

5.       Countersignature and Registration...................................  6

6.       Transfer,   Split   Up,   Combination   and   Exchange   of  Right
         Certificates;   Mutilated,   Destroyed,   Lost  or  Stolen   Right
         Certificate.........................................................  7

7.       Exercise of Rights; Purchase Price; Expiration Date of Rights.......  8

8.       Cancellation and Destruction of Right Certificates.................. 10

9.       Reservation and Availability of Capital Shares...................... 10

10.      Preferred Shares Record Date........................................ 11

11.      Adjustment of Purchase Price, Number of Shares or Number of Rights.. 11

12.      Certificate of Adjusted Purchase Price or Number of Shares.......... 19

13.      Consolidation,  Merger,  Statutory  Plan  of  Exchange  or Sale or
         Transfer of Assets or Earning Power................................. 20

14.      Fractional Rights and Fractional Shares............................. 23

15.      Rights of Action.................................................... 24

16.      Agreement of Right Holders.......................................... 25

17.      Right  Holders  and  Right   Certificate   Holders  Not  Deemed  a
         Shareholder......................................................... 25

18.      Concerning the Rights Agent......................................... 25

19.      Merger or Consolidation or Change of Name of Rights Agent........... 26

20.      Duties of Rights Agent.............................................. 27



                                   - i -

<PAGE>



21.      Change of Rights Agent.............................................. 29

22.      Issuance of New Right Certificates.................................. 30

23.      Redemption.......................................................... 31

24.      Exchange............................................................ 31

25.      Notice of Certain Events............................................ 32

26.      Notices............................................................. 33

27.      Supplements and Amendments.......................................... 34

28.      Certain Covenants................................................... 34

29.      Successors.......................................................... 35

30.      Benefits of This Agreement.......................................... 35

31.      Severability........................................................ 35

32.      Determinations and Actions by the Board of Directors, etc........... 35

33.      Governing Law....................................................... 36

34.      Counterparts........................................................ 36

35.      Descriptive Headings................................................ 36


     Exhibit A -- Form of Articles of Amendment

     Exhibit B -- Form of Right Certificate




                                   - ii -

<PAGE>



                           TABLE OF DEFINED TERMS

Term Defined                                                          Section

Acquiring Person                                                      1

Adjustment Shares                                                     11(a)(ii)

Affiliate                                                             1

Agreement                                                             Intro

Articles of Amendment                                                 Intro

Associate                                                             1

Beneficial Owner; beneficially own                                    1

Board of Directors                                                    Intro

Business Day                                                          1

close of business                                                     1

Common Shares                                                         1

common stock equivalents                                              11(a)(iii)

Company (Epitope, Inc.)                                               Intro

Company (Following a Section 13(a) event)                             13(a)

current per share market price of the
Common Shares                                                         11(d)(i)

current per share market price of the
Preferred Shares                                                      11(d)(ii)

Distribution Date                                                     3(a)

equivalent preferred shares                                           11(b)

Exchange Act                                                          1(b)

Exchange Date                                                         7(b)



                                  - iii -

<PAGE>



Term Defined                                                          Section

Exchange Ratio                                                        24(a)

Final Expiration Date                                                 7(b)

Nasdaq                                                                11(d)(i)

Person                                                                1

Plan (Employee benefit plan)                                          1(a)

Preferred Shares                                                      1

Principal Party                                                       13(b)

Purchase Price                                                        1

Qualifying Offer                                                      11(a)(ii)

Record Date                                                           Intro

Redemption Date                                                       7(b)

Redemption Price                                                      23(a)

Registered Common Shares                                              13(b)

Right                                                                 Intro

Right Certificate                                                     3(a)

Rights Agent                                                          Intro

Section 11(a)(ii) event                                               11(a)(ii)

Section 13 event                                                      13(a)

Securities Act                                                        7(d)

Shares Acquisition Date                                               1

Shareholder Rights Plan                                               1 (end)

Subsidiary                                                            1

Trading Day                                                           11(d)(i)



                                   - iv -

<PAGE>



                              RIGHTS AGREEMENT


               This Rights Agreement (the "Agreement") dated as of  December 15,
1997,  between  EPITOPE,  INC.,  an  Oregon  corporation  (the  "Company"),  and
CHASEMELLON  SHAREHOLDER  SERVICES,  L.L.C.,  a limited  liability  company (the
"Rights Agent");

                           W I T N E S S E T H :

               WHEREAS  the Board of  Directors  of the  Company  (the "Board of
Directors") has authorized the issuance of, and declared a dividend  payable in,
one right (a "Right") for each Common  Share (as defined  herein) of the Company
outstanding  on the record date to be  established  for the dividend  payable in
shares of Agritope, Inc., common stock that is to be declared in connection with
the spin-off of that corporation (the "Record Date"), upon the terms and subject
to the conditions herein set forth;

               WHEREAS  each such Right  shall  represent  the right to purchase
1/1,000 of a share of Series A Junior Participating  Cumulative Preferred Stock,
no par value,  of the  Company,  and shall have the rights and  preferences  set
forth in the form of Articles of Amendment  ("Articles of  Amendment")  attached
hereto as Exhibit A; and

               WHEREAS  the  Board  of  Directors  has  further  authorized  the
issuance  of one Right with  respect  to each  Common  Share  that shall  become
outstanding  between the Record Date and the earliest of the Distribution  Date,
the Redemption Date and the Final  Expiration Date (as such terms are defined in
Sections 3 and 7 hereof).

               NOW,  THEREFORE,  in consideration of the premises and the mutual
agreements herein set forth, the parties hereby agree as follows:

               Section 1. Certain  Definitions.  For purposes of this Agreement,
the following terms have the meanings indicated:

               (a)  "Acquiring  Person"  shall mean any Person (as  defined
         herein) who or which,  together with all Affiliates and Associates
         (as defined herein) of such Person,  shall be the Beneficial Owner
         (as defined  herein) of 15 percent or more of the Common Shares of
         the Company then outstanding, provided, however, that an Acquiring
         Person shall not include the Company,  any wholly owned Subsidiary
         (as defined  herein) of the  Company,  any  employee  benefit plan
         ("Plan") of the Company or of a Subsidiary of the Company,  or any
         Person holding Common Shares of the Company for or pursuant to the
         terms of any such  Plan.  Notwithstanding  the  foregoing:  (i) no
         Person  shall  become an  'Acquiring  Person'  as the result of an
         acquisition  of Common Shares of the Company by the Company which,
         by   reducing   the  number  of  Common   Shares  of  the  Company
         outstanding,  increases the proportionate  number of Common Shares
         of the Company beneficially owned



                                   - 1 -

<PAGE>



         by such  Person to 15 percent or more of the Common  Shares of the
         Company  then  outstanding,  provided,  however,  that if a Person
         shall  become  the  Beneficial  Owner of 15 percent or more of the
         Common  Shares of the Company then  outstanding  by reason of such
         share  acquisitions by the Company and shall thereafter become the
         Beneficial  Owner of any additional  Common Shares of the Company,
         then  such  Person  shall be deemed  to be an  'Acquiring  Person'
         unless upon the consummation of the acquisition of such additional
         Common  Shares of the Company  such Person does not own 15 percent
         or more of the Common Shares of the Company then outstanding;  and
         (ii) if the Board of  Directors  determines  in good  faith that a
         Person who would  otherwise be an 'Acquiring  Person'  became such
         inadvertently  (including,  without  limitation,  because (A) such
         Person was unaware that it beneficially  owned a percentage of the
         Common  Shares of the  Company  that  would  otherwise  cause such
         Person to be an 'Acquiring Person' or (B) such Person was aware of
         the extent of its  Beneficial  Ownership  of Common  Shares of the
         Company but had no actual  knowledge of the  consequences  of such
         Beneficial   Ownership  under  this  Agreement)  and  without  any
         intention of changing or influencing  control of the Company,  and
         if such  Person as  promptly  as  practicable  divested or divests
         itself of  Beneficial  Ownership of a sufficient  number of Common
         Shares of the  Company so that such  Person  would no longer be an
         'Acquiring Person',  then such Person shall not be deemed to be or
         to have  become an  'Acquiring  Person'  for any  purposes of this
         Agreement. For purposes of this subsection (a), in determining the
         percentage  of the  outstanding  shares  of  Common  Shares of the
         Company with respect to which a Person is the Beneficial Owner (i)
         all shares as to which such Person is deemed the Beneficial  Owner
         shall be deemed  outstanding  and (ii) shares which are subject to
         issuance upon the exercise or conversion of outstanding conversion
         rights, rights,  warrants and options other than those referred to
         in clause (i) of this  sentence  shall not be deemed  outstanding.
         Any determination made by the Board of Directors as to whether any
         Person is or is not an 'Acquiring  Person' shall be conclusive and
         binding upon all holders of Rights.

               (b) "Affiliate"  and  "Associate"  shall have the respective
         meanings ascribed to such terms in Rule 12b-2 of the General Rules
         and  Regulations  under the  Securities  Exchange Act of 1934,  as
         amended (the "Exchange Act"), as in effect on the date hereof.

               (c) A Person shall be deemed the  "Beneficial  Owner" of and
         shall be deemed to "beneficially own" any securities:

                    (i)  which  such   Person  or  any  of  such   Person's
         Affiliates   or   Associates   beneficially   owns,   directly  or
         indirectly,  for purposes of Section 13(d) of the Exchange Act and
         Regulation 13D-G thereunder (or



                                   - 2 -

<PAGE>



         any comparable or successor law or regulation), in each case as in
         effect on the date hereof; or

                    (ii)  which  such  Person  or  any  of  such   Person's
         Affiliates  or  Associates  has (A) the right to acquire  (whether
         such right is exercisable immediately or only after the passage of
         time or the  fulfillment  of a condition or both)  pursuant to any
         agreement,  arrangement  or  understanding  (other than  customary
         arrangements with and among underwriters and selling group members
         with  respect to a bona fide public  offering of  securities),  or
         upon the exercise of conversion  rights,  exchange rights,  rights
         (other than these  Rights),  warrants or  options,  or  otherwise;
         provided,   however,  that  a  Person  shall  not  be  deemed  the
         Beneficial Owner of, or to beneficially own,  securities  tendered
         pursuant  to a tender or  exchange  offer  made by or on behalf of
         such Person or any of such Person's Affiliates or Associates until
         such tendered securities are accepted for purchase or exchange; or
         (B) the right to vote,  alone or in concert with others,  pursuant
         to any agreement, arrangement or understanding; provided, however,
         that a Person shall not be deemed the  Beneficial  Owner of, or to
         beneficially  own, any security if the  agreement,  arrangement or
         understanding  to vote such  security  (1)  arises  solely  from a
         revocable  proxy  given  to such  Person  or any of such  Person's
         Affiliates   or   Associates   in  response  to  a  public   proxy
         solicitation  made  pursuant  to,  and  in  accordance  with,  the
         applicable  rules and  regulations  of the Exchange Act and (2) is
         not also then  reportable  on Schedule  13D under the Exchange Act
         (or any comparable or successor report); or

                    (iii)  which  are  beneficially   owned,   directly  or
         indirectly,  by any other  Person with which such Person or any of
         such  Person's   Affiliates  or  Associates   has  any  agreement,
         arrangement or  understanding  (other than customary  arrangements
         with and among underwriters and selling group members with respect
         to a bona fide public  offering of securities)  for the purpose of
         acquiring,  holding,  voting  (other  than  voting  pursuant  to a
         revocable   proxy  as   described   in  the   proviso  to  Section
         1(c)(ii)(B)) or disposing of any securities of the Company.

               (d) "Business Day" shall mean any day other than a Saturday,
         Sunday or a day on which banking  institutions in the state of New
         York are  authorized  or obligated  by law or  executive  order to
         close.

               (e) "Close of business" on any given date shall mean 5 p.m.,
         New York City time, on such date; provided,  however, that if such
         date is not a  Business  Day it shall  mean 5 p.m.,  New York City
         time, on the next succeeding Business Day.



                                   - 3 -

<PAGE>



               (f) "Common  Shares" when used with reference to the Company
         shall mean shares of common stock,  no par value,  of the Company.
         "Common  Shares" when used with reference to any Person other than
         the Company  shall mean shares of the common  stock of such Person
         (or other class of equity  securities or equity  interests) having
         power to control or direct the  management  of such  Person or, if
         such Person is a Subsidiary of another Person, of the Person which
         ultimately  controls  such  first-mentioned  Person  and which has
         issued and  outstanding  such common stock (or such other class of
         equity securities or equity interests).

               (g) "Person" shall mean any individual,  firm,  partnership,
         corporation,  association,  group  (as  such  term is used in Rule
         13d-5 under the Exchange Act) or other  entity,  and shall include
         any successor (by merger or otherwise) of such entity.

               (h) "Preferred  Shares" shall mean shares of Series A Junior
         Participating  Cumulative  Preferred  Stock,  no par value, of the
         Company.

               (i)  "Purchase  Price"  shall  mean the price to be paid for
         each  1/1,000 of a Preferred  Share  pursuant to the exercise of a
         Right,  which  price  is, as of the date  hereof,  as set forth in
         Section 7(c).  The Purchase  Price is subject to  adjustment  from
         time to time as set forth in Sections 11 and 13.

               (j) "Shares  Acquisition  Date" shall mean the first date of
         public  announcement  (which, for the purposes of this definition,
         shall  include,  without  limitation,  a report filed  pursuant to
         Section  13(d)  under  the  Exchange  Act)  by the  Company  or an
         Acquiring Person that an Acquiring Person has become such.

               (k) "Subsidiary" of any Person shall mean any corporation or
         other entity of which a majority of the voting  equity  securities
         or equity  interests  is owned,  directly or  indirectly,  by such
         Person.

               The terms and conditions  embodied in this Rights  Agreement,  as
from time to time amended,  may be referred to as the "Shareholder  Rights Plan"
of the Company.

               Section  2.  Appointment  of Rights  Agent.  The  Company  hereby
appoints the Rights Agent to act as agent for the Company in accordance with the
terms  and  conditions   hereof,  and  the  Rights  Agent  hereby  accepts  such
appointment.  The Company may from time to time appoint such co-Rights Agents as
it may deem necessary or desirable.

               Section 3. Issuance of Right Certificates.

               (a) Until the  earlier of the close of  business  on (i) the 10th
day after the Shares  Acquisition  Date or (ii) the 10th  Business  Day (or such
later date as may be determined by the



                                      - 4 -

<PAGE>



Board of  Directors of the Company  prior to such time as any Person  becomes an
Acquiring  Person) after the date of the  commencement by any Person (other than
the Company, any wholly owned Subsidiary of the Company, any Plan of the Company
or of any Subsidiary of the Company,  or any entity holding Common Shares of the
Company  for or  pursuant  to the terms of any such  Plan)  of, or first  public
announcement of the intent of any such Person to commence,  a tender or exchange
offer,  the  consummation  of which would  result in  beneficial  ownership by a
Person,  together with its Affiliates and  Associates,  of 15 percent or more of
the outstanding  Common Shares of the Company,  including any such date which is
after the date of this  Agreement  and prior to the  issuance of the Rights (the
earlier of (i) and (ii) being herein  referred to as the  "Distribution  Date"),
then the following shall apply: (x) the Rights will be evidenced by certificates
for Common Shares of the Company (which  certificates shall also be deemed to be
Right  Certificates) or, as the case may be,  certificates  issued subsequent to
the Record Date and bearing the legend set forth in Section 3(b) hereof (and, in
neither case, by separate  Right  Certificates)  and the record  holders of such
certificates  for  Common  Shares  shall be the  record  holders  of the  Rights
represented  thereby  and  (y)  the  Rights  and  the  right  to  receive  Right
Certificates will be transferable only simultaneously with and together with the
transfer of Common Shares of the Company.  Until the  Distribution  Date (or the
earlier of the Redemption Date or the Final Expiration  Date), the surrender for
transfer  of such  certificates  for Common  Shares  shall also  constitute  the
surrender  for  transfer  of  the  Rights  associated  with  the  Common  Shares
represented  thereby.  As soon as practicable after the Distribution Date, after
notification  by the  Company,  the  Rights  Agent will  send,  by  first-class,
postage-prepaid  mail,  to each record holder of Common Shares of the Company as
of the close of business on the Distribution Date, at the address of such holder
shown on the records of the Company, a Right  Certificate,  in substantially the
form of Exhibit B hereto,  evidencing  one Right for each Common  Share so held,
subject to adjustment  as provided  herein.  As of the  Distribution  Date,  the
Rights  will  be  evidenced  solely  by  such  Right  Certificates  and  may  be
transferred  by the  transfer of the Right  Certificates  as  permitted  hereby,
separately  and apart from any transfer of one or more shares of Common  Shares,
and the  holders  of such  Right  Certificates  as listed in the  records of the
Company or any transfer  agent or  registrar  for the Rights shall be the record
holders thereof.

               (b) Rights shall be issued in respect of all Common Shares of the
Company  issued  after  the  Record  Date,  but  prior  to the  earliest  of the
Distribution  Date,  the  Redemption  Date,  the  Exchange  Date,  or the  Final
Expiration Date.  Certificates for such Common Shares shall also be deemed to be
certificates  for Rights and shall have  impressed on, printed on, written on or
otherwise affixed to them the following legend:

         This  certificate also evidences and entitles the holder hereof to
         certain  Rights as set  forth in the  Shareholder  Rights  Plan of
         Epitope,  Inc. (the "Plan"),  until separate certificates for such
         Rights are issued.  Under certain  circumstances,  as set forth in
         the Plan,  such Rights will be evidenced by separate  certificates
         and will no longer be evidenced by this certificate.  The terms of
         the Plan,  a copy of which is on file at the  principal  executive
         offices  of  Epitope,  Inc.,  are  hereby  incorporated  herein by
         reference.  Epitope, Inc., shall mail or cause to be mailed to the
         holder of this certificate a copy of the Plan without



                                   - 5 -

<PAGE>



         charge promptly  following  receipt of a written request therefor.
         Under  certain   circumstances  set  forth  in  the  Plan,  Rights
         beneficially  owned  by any  Person  who  is,  was or  becomes  an
         Acquiring  Person or any  Affiliate or Associate  thereof (as such
         terms are defined in the Plan) and any  subsequent  holder of such
         Rights, may become null and void.

               (c)  Certificates  for Common  Shares,  if any,  issued after the
Distribution  Date but prior to the earlier of the Redemption  Date or the Final
Expiration  Date shall have  impressed on,  printed on,  written on or otherwise
affixed to them the following legend:

         This  certificate  does not evidence any Right issued  pursuant to
         the terms of the Shareholder Rights Plan of Epitope, Inc.

               Section  4. Form of Right  Certificates.  The Right  Certificates
(and the forms of election to purchase, assignment and certificate to be printed
on the reverse thereof), when, as and if issued, shall be substantially the same
as Exhibit B hereto and may have such marks of identification or designation and
such legends,  summaries or endorsements printed thereon as the Company may deem
appropriate and as are not  inconsistent  with the provisions of this Agreement,
or as may be  required  to comply  with any  applicable  law or with any rule or
regulation  made  pursuant  thereto or with any rule or  regulation of any stock
exchange  on which the Common  Shares of the Company or the Rights may from time
to time be listed, or to conform to usage.  Subject to the provisions of Section
11 and Section 22 hereof,  the Right  Certificates,  whenever issued,  which are
issued in respect of Common Shares which were issued and  outstanding  as of the
close of business on the  Distribution  Date,  shall be dated as of the close of
business on the  Distribution  Date, and on their face shall entitle the holders
thereof to purchase such number of Preferred Shares (including fractional shares
which  are  integral  multiples  of  1/1,000  of a share)  as shall be set forth
therein at the price per 1/1,000 of a Preferred Share set forth therein, but the
number of such  Preferred  Shares and fractions  thereof and the Purchase  Price
shall be subject to adjustment as provided herein.

               Section 5. Countersignature and Registration.

               (a) The Right  Certificates  shall be  executed  on behalf of the
Company by its  Chairman  of the Board,  its  President  or any Vice  President,
either  manually  or by  facsimile  signature,  and  have  affixed  thereto  the
Company's seal or a facsimile  thereof which shall be attested by the Secretary,
or an  Assistant  Secretary,  of the  Company,  either  manually or by facsimile
signature.  The Right  Certificates  shall be countersigned by the Rights Agent,
either  manually or by facsimile,  and shall not be valid for any purpose unless
so  countersigned.  In case any officer of the Company who shall have signed any
of the Right  Certificates  shall cease to be such officer of the Company before
countersignature  by the Rights  Agent and issuance and delivery by the Company,
such Right Certificates, nevertheless, may be countersigned by the Rights Agent,
and issued and delivered by the Company with the same force and effect as though
the person who signed such Right  Certificates had not ceased to be such officer
of the Company; and any Right Certificate may be signed on behalf of the Company
by  any  person  who,  at the  actual  date  of  the  execution  of  such  Right
Certificate, shall be a proper officer of



                                      - 6 -

<PAGE>



the  Company  to  sign  such  Right  Certificate,  although  at the  date of the
execution of this Agreement any such person was not such an officer.

               (b) Following the  Distribution  Date, the Rights Agent will keep
or cause to be kept, at its shareholder  services office, books for registration
and transfer of the Right Certificates  issued hereunder.  Such books shall show
the names and addresses of the respective holders of the Right Certificates, the
number of Rights evidenced on its face by each of the Right Certificates and the
date of each of the Right Certificates.

               Section 6. Transfer,  Split Up, Combination and Exchange of Right
Certificates; Mutilated, Destroyed, Lost or Stolen Right Certificate.

               (a) Subject to the provisions of Sections 7(f) and 14 hereof,  at
any time after the close of business on the  Distribution  Date, and at or prior
to the close of business on the earliest of the  Redemption  Date,  the Exchange
Date, or the Final Expiration Date, any Right Certificate or Right  Certificates
may  be  transferred,   split  up,  combined  or  exchanged  for  another  Right
Certificate or Right Certificates, entitling the registered holder to purchase a
like number of Preferred Shares as the Right  Certificate or Right  Certificates
surrendered  then  entitled  such  holder to  purchase.  Any  registered  holder
desiring to transfer,  split up, combine or exchange any Right Certificate shall
make such request in writing  delivered to the Rights Agent, and shall surrender
the  Right  Certificate  or Right  Certificates  to be  transferred,  split  up,
combined  or  exchanged  at the  office  of the  Rights  Agent  with the form of
assignment on the reverse side thereof (or with a written instrument of transfer
in form  satisfactory  to the Company and the Rights  Agent  enclosed  with such
Right  Certificate),  executed by the registered  holder thereof or his attorney
authorized in writing,  and with such signature  guaranteed.  Neither the Rights
Agent nor the Company  shall be  obligated  to take any action  whatsoever  with
respect to the  transfer of any such  surrendered  Right  Certificate  until the
certificate  set forth in the form of  assignment  on the  reverse  side of such
Right  Certificate  shall have been  completed  and  executed by the  registered
holder  thereof or his attorney  authorized in writing,  and with such signature
guaranteed, and the Company shall have been provided such additional evidence of
the identity of the Beneficial Owner (or former  Beneficial Owner) of the Rights
represented  by such Right  Certificate  or the Affiliates or Associates of such
Beneficial  Owner (or former  Beneficial  Owner) as the Company shall reasonably
request. Upon receipt of such executed form of assignment and certificate and of
such additional evidence,  if requested,  the Rights Agent shall countersign and
deliver  to  the  person   entitled   thereto  a  Right   Certificate  or  Right
Certificates,  as the case may be, as so  requested.  The  Company  may  require
payment of a sum sufficient to cover any tax or governmental  charge that may be
imposed in connection  with any transfer,  split up,  combination or exchange of
Right Certificates.

               (b) Upon  receipt by the Company and the Rights Agent of evidence
reasonably satisfactory to them of the loss, theft, destruction or mutilation of
a Right Certificate, and, in case of loss, theft or destruction, of indemnity or
security  reasonably  satisfactory  to  them,  and,  at the  Company's  request,
reimbursement  to the Company and the Rights  Agent of all  reasonable  expenses
incidental  thereto,  and upon surrender to the Rights Agent and cancellation of
the Right  Certificate  if mutilated,  the Company shall issue and deliver a new
Right Certificate of like tenor



                                      - 7 -

<PAGE>



to the Rights  Agent for delivery to the  registered  owner in lieu of the Right
Certificate so lost, stolen, destroyed or mutilated.

               Section 7. Exercise of Rights; Purchase Price; Expiration Date of
Rights.

               (a) Until the Distribution Date, no Right may be exercised.

               (b) The registered  holder of any Right  Certificate may exercise
the Rights evidenced  thereby (except as otherwise  provided herein) in whole or
in part at any time  after the  Distribution  Date upon  surrender  of the Right
Certificate,  with the form of election to purchase on the reverse  side thereof
and certificate thereon duly executed (with signatures duly guaranteed),  to the
Rights Agent at the  shareholder  services  office or agency of the Rights Agent
designated  for such purpose,  together with payment of the Purchase  Price with
respect to each Right exercised, at or prior to the earliest of (i) the close of
business on the tenth  anniversary  of the Record  Date (the  "Final  Expiration
Date"), (ii) the time at which the Rights are exchanged (the "Exchange Date") as
provided in Section 24, or (iii) the time at which the Rights are redeemed  (the
"Redemption Date"), as provided in Section 23 hereof.

               (c) The  Purchase  Price for each  1/1,000 of a  Preferred  Share
pursuant to the exercise of a Right shall initially be $60, and shall be payable
in lawful money of the United States of America in accordance  with Section 7(d)
hereof.  The Purchase  Price and the number or type of securities to be acquired
upon  exercise  of a Right shall be subject to  adjustment  from time to time as
provided in Sections 11 and 13 hereof.

               (d) Upon receipt of a Right Certificate  representing exercisable
Rights,  with the form of election to purchase and form of  certificate  thereon
duly executed, accompanied by payment of the Purchase Price for the shares to be
purchased and an amount equal to any applicable transfer tax required to be paid
by the holder of such Right  Certificate  in  accordance  with Section 9 by bank
certified check or cashier's check payable to the order of the Company, and such
additional  evidence  of  the  identity  of  the  Beneficial  Owner  (or  former
Beneficial  Owner) of the Rights  represented  by such Right  Certificate or the
Affiliates  or Associates  thereof as the Company may  reasonably  request,  the
Rights Agent shall thereupon promptly (i) requisition from any transfer agent of
the  Preferred  Shares  certificates  for the number of  Preferred  Shares to be
purchased and the Company  hereby  irrevocably  authorizes its transfer agent to
comply  with all such  requests,  and/or,  as  provided  in  Section  14 hereof,
requisition  from the depositary  agent depositary  receipts  representing  such
number of 1/1,000s of a Preferred  Share as are to be  purchased  (in which case
certificates  for the Preferred  Shares  represented  by such receipts  shall be
deposited  by the  transfer  agent with the  depositary  agent) and the  Company
hereby  directs  the  depositary  agent to comply with such  request,  (ii) when
appropriate,  requisition from the Company the amount of cash to be paid in lieu
of issuance of fractional  shares in accordance  with Section 14, (iii) promptly
after receipt of such certificates or depositary receipts,  cause the same to be
delivered  to or  upon  the  order  of  the  registered  holder  of  such  Right
Certificate,  registered  in such  name or  names as may be  designated  by such
holder and (iv) when appropriate,  after receipt,  promptly deliver such cash to
or  upon  the  order  of  the  registered  holder  of  such  Right  Certificate.
Notwithstanding the foregoing provisions of



                                      - 8 -

<PAGE>



this Section 7(d), the Company may suspend the issuance of Preferred Shares upon
exercise of Rights for a  reasonable  period,  not in excess of 90 days,  during
which the Company seeks to register under the Securities Act of 1933, as amended
(the "Securities  Act"), and any applicable  securities law of any jurisdiction,
the Preferred  Shares to be issued  pursuant to the Rights;  provided,  however,
that nothing  contained  in this  Section 7(d) shall  relieve the Company of its
obligations under Section 9(c) hereof.

               (e) In case the registered  holder of any Right Certificate shall
exercise less than all the Rights  evidenced  thereby,  a new Right  Certificate
evidencing Rights equivalent to the Rights remaining unexercised shall be issued
by the Rights Agent to the registered holder of such Right Certificate or to his
duly authorized assigns, subject to the provisions of Section 14 hereof.

               (f)  Notwithstanding  anything in this Agreement to the contrary,
upon the occurrence of a Section 11(a)(ii) event or Section 13 event, any Rights
beneficially  owned by (i) an Acquiring  Person or any Affiliate or Associate of
an  Acquiring  Person,  (ii)  a  transferee  of an  Acquiring  Person  or of any
Affiliate or Associate of such Acquiring  Person who becomes a transferee  after
the  Acquiring  Person  becomes  such,  or (iii) a transferee  who acquired such
Rights from an  Acquiring  Person or an  Affiliate  or Associate of an Acquiring
Person prior to or concurrently  with the Acquiring Person becoming such and who
receives  such  Rights  pursuant  to either (A) a transfer  (whether  or not for
consideration)  from an Acquiring  Person or any  Affiliate or Associate of such
Acquiring  Person to  holders  of equity  interests  in such  Acquiring  Person,
Affiliate or Associate or to any Person with whom such  Acquiring  Person or any
such  Associate  or  Affiliate  has any  continuing  agreement,  arrangement  or
understanding regarding the transferred Rights or (B) a transfer which the Board
of Directors has determined  (whether  before or after such transfer) to be part
of an arrangement which has as a primary purpose or effect the avoidance of this
Section 7(f), shall become null and void, and any holder of such Rights (whether
or not such holder is an  Acquiring  Person or an  Affiliate  or Associate of an
Acquiring  Person) shall  thereafter have no right to exercise such Rights under
any  provision of this  Agreement or  otherwise.  Any Right  Certificate  issued
pursuant to Section 3 that represents Rights  beneficially owned by an Acquiring
Person or any Affiliate or Associate thereof and any Right Certificate issued at
any time upon the transfer of any Rights to an Acquiring Person or any Affiliate
or Associate  thereof or to any nominee of such Acquiring  Person,  Affiliate or
Associate,  and any Right  Certificate  issued pursuant to Sections 6 or 11 upon
transfer,  exchange,  replacement  or adjustment of any other Right  Certificate
referred to in this sentence,  shall or shall be deemed to contain the following
legend:

         The  Rights  represented  by this  Right  Certificate  are or were
         beneficially  owned by a Person  who was or  became  an  Acquiring
         Person or Affiliate  or Associate of an Acquiring  Person (as such
         terms are  defined in the  Shareholder  Rights  Plan).  This Right
         Certificate  and the  Rights  represented  hereby  are void in the
         circumstances specified in the Shareholder Rights Plan.




                                                     - 9 -

<PAGE>



The Company shall use all  reasonable  efforts to ensure that the  provisions of
this Section 7(f) are complied  with,  but shall have no liability to any holder
of  Rights  or  any  other  Person  as a  result  of its  failure  to  make  any
determination under this Section 7(f) with respect to an Acquiring Person or its
Affiliates, Associates or transferees.

               Section 8.  Cancellation  and Destruction of Right  Certificates.
All Right Certificates surrendered for the purpose of exercise,  transfer, split
up,  combination or exchange  shall,  if surrendered to the Company or to any of
its agents,  be delivered to the Rights  Agent for  cancellation  or in canceled
form, or, if  surrendered  to the Rights Agent,  shall be canceled by it, and no
Right Certificates shall be issued in lieu thereof except as expressly permitted
by any of the  provisions  of this  Agreement.  The Company shall deliver to the
Rights  Agent for  cancellation  and  retirement,  and the Rights Agent shall so
cancel and retire,  any other  Right  Certificate  purchased  or acquired by the
Company otherwise than upon the exercise thereof. The Rights Agent shall deliver
all canceled Right Certificates to the Company, or shall, at the written request
of the Company, destroy such canceled Right Certificates, and in such case shall
deliver a certificate of destruction thereof to the Company.

               Section 9. Reservation and Availability of Capital Shares.

               (a) The  Company  covenants  and agrees  that it will cause to be
reserved and kept available out of its authorized and unissued  Preferred Shares
(and, will use its best efforts, following the occurrence of a Section 11(a)(ii)
event,  to cause to be reserved and kept  available  out of its  authorized  and
unissued  Common Shares and/or other  securities  or out of its  authorized  and
issued  shares  held in its  treasury),  the number of  Preferred  Shares  (and,
following the  occurrence  of a Section  11(a)(ii)  event,  the number of Common
Shares  and/or  other  securities)  as will from time to time be  sufficient  to
permit the exercise in full of all outstanding Rights.

               (b) If and so long as the  Preferred  Shares (and,  following the
occurrence of a Section 11(a)(ii) event,  Common Shares and/or other securities)
issuable  upon the exercise of Rights may be listed on any  national  securities
exchange,  the Company shall use its best efforts to cause,  from and after such
time as the Rights  become  exercisable,  all shares issued or reserved for such
issuance to be listed on such  exchange  upon  official  notice of issuance upon
such exercise.

               (c) If necessary  to permit the  issuance of shares  and/or other
securities  pursuant  to  the  Rights,  the  Company  will  prepare  and  file a
registration  statement  under the  Securities  Act with  respect to such shares
and/or other  securities on an  appropriate  form, use its best efforts to cause
such  registration  statement to become  effective as soon as practicable  after
such filing and use its best  efforts to cause such  registration  statement  to
remain effective (with a prospectus at all times meeting the requirements of the
Securities  Act) until the Final  Expiration  Date,  and  similarly  comply with
applicable state securities laws.

               (d) The Company  covenants  and agrees that it will take all such
action as may be necessary to ensure that all 1/1,000s of Preferred Shares (and,
following the  occurrence  of a Section  11(a)(ii)  event,  Common Shares and/or
other securities) delivered upon exercise of



                                     - 10 -

<PAGE>



Rights  shall,  at the time of delivery of the  certificates  for such shares or
other securities (subject to payment of the Purchase Price), be duly and validly
authorized and issued and fully paid and nonassessable.

               (e) The  Company  further  covenants  and agrees that it will pay
when due and payable any and all  federal and state  transfer  taxes and charges
which may be  payable  in  respect  of the  issuance  or  delivery  of the Right
Certificates  or  of  any  Preferred  Shares  (or  Common  Shares  and/or  other
securities  as the case may be) upon the exercise of Rights.  The Company  shall
not,  however,  be  required  to pay any  transfer  tax which may be  payable in
respect of any  transfer  or delivery of Right  Certificates  to a Person  other
than, or the issuance or delivery of certificates  for the Preferred  Shares (or
Common Shares and/or other securities,  as the case may be) in a name other than
that of,  the  registered  holder of the  Right  Certificate  evidencing  Rights
surrendered for exercise or to issue or deliver any  certificates  for Preferred
Shares (or Common Shares and/or other  securities,  as the case may be) upon the
exercise  of any  Rights  until any such tax shall  have been paid (any such tax
being payable by the holder of such Right  Certificate at the time of surrender)
or until it has been established to the Company's  satisfaction that no such tax
is due.

               Section 10.  Preferred  Shares Record Date.  Each Person in whose
name any  certificate  for  Preferred  Shares (or  Common  Shares  and/or  other
securities,  as the case may be) is issued upon the exercise of Rights shall for
all  purposes  be deemed to have  become the  holder of record of the  Preferred
Shares  (or  Common  Shares  and/or  other  securities,  as  the  case  may  be)
represented thereby on, and such certificate shall be dated, the date upon which
the Right Certificate evidencing such Rights was duly surrendered and payment of
the  Purchase  Price (and any  applicable  transfer  taxes) was made;  provided,
however, that if the date of such surrender and payment is a date upon which the
transfer  books  for  the  Preferred  Shares  (or  Common  Shares  and/or  other
securities,  as the case may be) are closed, such Person shall be deemed to have
become the record holder of such shares on, and such certificate shall be dated,
the next succeeding Business Day on which such transfer books are open.

               Section 11.  Adjustment  of Purchase  Price,  Number of Shares or
Number of Rights. The Purchase Price, the number and kind of shares which may be
purchased  upon  exercise  of a Right and the number of Rights  outstanding  are
subject to adjustment from time to time as provided in this Section 11.

               (a) (i) In the event the Company shall at any time after the
     date of this  Agreement  and  prior to the  close of  business  on the
     earliest of the Redemption  Date,  Exchange Date, or Final  Expiration
     Date (A) declare or pay any dividend on the Preferred  Shares  payable
     in Preferred Shares,  (B) subdivide the outstanding  Preferred Shares,
     (C) combine the outstanding  Preferred Shares into a smaller number of
     Preferred  Shares or (D) issue any  shares of its  capital  stock in a
     reclassification   of  the  Preferred   Shares   (including  any  such
     reclassification in connection with a consolidation or merger in which
     the Company is the continuing or surviving  corporation),  then and in
     each such event, the Purchase Price in effect at the time of the



                                                     - 11 -

<PAGE>



     record  date  for  such  dividend  or on the  effective  date  of such
     subdivision, combination or reclassification,  and the number and kind
     of Preferred  Shares or capital stock, as the case may be, issuable on
     such date, shall be proportionately adjusted so that the holder of any
     Right  exercised  after such time  shall be  entitled  to receive  the
     aggregate number and kind of Preferred Shares or capital stock, as the
     case may be, which, if such Right had been exercised immediately prior
     to such  date and at a time when the  Right  was  exercisable  and the
     transfer books of the Company were open, he would have owned upon such
     exercise  and been  entitled  to receive  by virtue of such  dividend,
     subdivision, combination or reclassification. If an event occurs which
     would  require an  adjustment  under both this  Section  11(a)(i)  and
     Section 11(a)(ii) hereof, the adjustment  provided for in this Section
     11(a)(i)  shall be in  addition  to,  and shall be made  prior to, any
     adjustment required pursuant to Section 11(a)(ii) hereof.

                    (ii)  Subject to Section 24, in the event that,  at any
     time after the date of this  Agreement  any Person,  alone or together
     with its Affiliates and Associates,  shall become an Acquiring Person,
     other  than by an  acquisition  of  Common  Shares  pursuant  to (A) a
     transaction to which the provisions of Section 13(a) hereof apply,  or
     (B) a tender  offer or an exchange  offer for all  outstanding  Common
     Shares at a price and on terms  determined  by at least a majority  of
     the  members of the Board of  Directors  who are not  officers  of the
     Company  and who  are not  representatives,  nominees,  Affiliates  or
     Associates of an Acquiring Person,  after receiving advice from one or
     more investment banking firms, to be fair to the holders of the Common
     Shares (taking into account all factors that such members of the Board
     deem  relevant  including,  without  limitation,   prices  that  could
     reasonably  be  achieved  if the Company or its assets were sold on an
     orderly basis designed to realize  maximum value) and otherwise in the
     best  interests  of the Company and its  shareholders  (a  "Qualifying
     Offer"),  then,  immediately  upon  the  occurrence  of such  event (a
     "Section  11(a)(ii)  event"),  proper  provision shall be made so that
     each holder of a Right,  except as provided  in Section  7(f)  hereof,
     shall thereafter have a right to receive for each Right, upon exercise
     thereof in accordance  with the terms of this Agreement and payment of
     the  then-current  Purchase  Price,  in lieu of 1/1,000 of a Preferred
     Share,  such number of Common Shares of the Company as shall equal the
     result obtained by multiplying the then-current  Purchase Price by the
     then number of  1/1,000s  of a  Preferred  Share for which a Right was
     exercisable  immediately  prior to the first  occurrence  of a Section
     11(a)(ii)  event,  and  dividing  that  product  by 50  percent of the
     current per share market price  (determined  pursuant to Section 11(d)
     hereof) for Common Shares on the date of such first  occurrence  (such
     number of shares  being  hereinafter  referred  to as the  "Adjustment
     Shares");  provided that such provision  shall not be effective  until
     such time as the Rights are no longer  subject to redemption  pursuant
     to Section 23(a) hereof.



                                   - 12 -

<PAGE>




                    (iii) In lieu of issuing  Common  Shares in  accordance
     with  Section  11(a)(ii)  hereof,  the  Company  may,  if the Board of
     Directors  determines that such action is necessary or appropriate and
     not contrary to the  interest of holders of Rights,  and, in the event
     that the number of Common Shares which are authorized by the Company's
     Articles of Incorporation but not outstanding or reserved for issuance
     for purposes  other than upon exercise of the Rights is not sufficient
     to  permit  the  exercise  in full of the  Rights in  accordance  with
     Section  11(a)(ii)  hereof,  the Company  shall,  with respect to each
     Right,  make adequate  provision to substitute for all or a portion of
     the Adjustment  Shares upon payment of the  applicable  Purchase Price
     (A) cash,  (B) other  equity  securities  of the  Company  (including,
     without  limitation,  shares of preferred  stock or units of preferred
     stock having the same value as Common  Shares (such shares or units of
     preferred stock, "common stock equivalents")),  (C) debt securities of
     the Company, (D) other assets or (E) any combination of the foregoing,
     having an aggregate  value equal to the amount obtained by multiplying
     the current per share  market  price for Common  Shares on the date of
     the  substitution  by  the  number  of  Adjustment  Shares  for  which
     substitution  is made. To the extent that the Company  determines that
     some action is to be taken  pursuant to this Section  11(a)(iii),  the
     Company  shall  provide,  subject to Section  7(f)  hereof,  that such
     action shall apply uniformly to all outstanding Rights.

               (b) In the event  that the  Company  shall at any time after
     the close of  business  on the  Record  Date and prior to the close of
     business on the earliest of the  Redemption  Date,  Exchange  Date, or
     Final  Expiration Date fix a record date prior to the Redemption Date,
     Exchange  Date, or Final  Expiration  Date for the issuance of rights,
     options or warrants to all holders of Preferred  Shares entitling them
     (for a period expiring within 45 calendar days after such record date)
     to subscribe  for or purchase  Preferred  Shares (or shares having the
     same  rights,  privileges  and  preferences  as the  Preferred  Shares
     ("equivalent   preferred  shares"))  or  securities  convertible  into
     Preferred  Shares  or  equivalent  preferred  shares,  at a price  per
     Preferred  Share or per  equivalent  preferred  share  (or  having  an
     effective  price  per  share  on a  converted  basis  in the case of a
     security  convertible  into Preferred  Shares or equivalent  preferred
     shares) less than the current per share market price of the  Preferred
     Shares (as determined in accordance with Section 11(d) hereof) on such
     record date, then the Purchase Price to be in effect after such record
     date shall be determined by  multiplying  the Purchase Price in effect
     immediately prior to such record date by a fraction,  the numerator of
     which  shall be the number of  Preferred  Shares  outstanding  on such
     record date plus the number of Preferred  Shares  which the  aggregate
     offering  price  of  the  total  number  of  Preferred  Shares  and/or
     equivalent  preferred  shares so to be offered  (and/or the  aggregate
     price of the  convertible  securities so to be offered) would purchase
     at such current  market price,  and the  denominator of which shall be
     the number of Preferred Shares outstanding on such record



                                   - 13 -

<PAGE>



     date plus the number of additional  Preferred Shares and/or equivalent
     preferred  shares to be offered for  subscription or purchase (or into
     which  the  convertible  securities  so to be  offered  are  initially
     convertible).  In case such subscription price may be paid by delivery
     of  consideration  part or all of which  may be in a form  other  than
     cash, the value of such  consideration  shall be as determined in good
     faith by the  Board of  Directors,  whose  determination  shall be set
     forth in a statement  filed with the Rights Agent and shall be binding
     on the Rights  Agent and the holders of the Rights.  Preferred  Shares
     owned by or held for the  account of the  Company  shall not be deemed
     outstanding for the purpose of any such  computation.  Such adjustment
     shall be made  successively  whenever such a record date is fixed; and
     in the event that such rights,  options or warrants are not so issued,
     the Purchase  Price shall be adjusted to be the  Purchase  Price which
     would then be in effect if such record date had not been fixed.

               (c) In the event  that the  Company  shall at any time after
     the close of  business  on the  Record  Date and prior to the close of
     business on the earliest of the  Redemption  Date,  Exchange  Date, or
     Final  Expiration  Date  fix  a  record  date  for  the  making  of  a
     distribution  to all holders of the Preferred  Shares  (including  any
     such distribution made in connection with a consolidation or merger in
     which the  Company is the  continuing  corporation)  of  evidences  of
     indebtedness  or assets (other than a regular  quarterly cash dividend
     or a dividend payable in Preferred  Shares) or subscription  rights or
     warrants  (excluding those referred to in Section 11(b)), the Purchase
     Price to be in effect  after such record date shall be  determined  by
     multiplying  the Purchase  Price in effect  immediately  prior to such
     record date by a fraction, the numerator of which shall be the current
     per share  market  price per one  Preferred  Share (as  determined  in
     accordance  with Section 11(d)  hereof) on such record date,  less the
     fair  market  value of the  portion  of the  assets  or  evidences  of
     indebtedness  so to be distributed or of such  subscription  rights or
     warrants  applicable to one Preferred  Share,  and the  denominator of
     which shall be such current per share  market price per one  Preferred
     Share.  Such adjustments  shall be made  successively  whenever such a
     record date is fixed;  and in the event that such  distribution is not
     so made, the Purchase Price shall again be adjusted to be the Purchase
     Price  which  would then be in effect if such record date had not been
     fixed.

               (d) (i) For the purpose of any  computation  hereunder,  the
     "current  per share  market  price" of the  Common  Shares on any date
     shall be deemed to be the  average  of the daily  closing  prices  per
     share of such Common Shares on each of the 20 consecutive Trading Days
     (as such  term is  hereinafter  defined)  through  and  including  the
     Trading Day immediately  preceding such date; provided,  however, that
     in the event the current per share market  price of the Common  Shares
     is determined during a period following the announcement by the issuer
     of such Common Shares of (A) a



                                   - 14 -

<PAGE>



     dividend or  distribution on such Common Shares payable in such Common
     Shares or securities  convertible into such Common Shares,  or (B) any
     subdivision,  combination,  or reclassification of such Common Shares,
     and prior to the  expiration of 20 Trading Days after the  ex-dividend
     date for such dividend,  distribution,  subdivision,  combination,  or
     reclassification,  then,  and in each such case the  current per share
     market price shall be appropriately adjusted to take into account such
     event.  The  closing  price for each day shall be the last sale price,
     regular  way,  or, in case no such sale takes  place on such day,  the
     average of the closing bid and asked  prices,  regular  way, in either
     case as reported in the principal  consolidated  transaction reporting
     system with respect to securities listed or admitted to trading on the
     principal national  securities exchange on which the Common Shares are
     listed or admitted to trading or, if the Common  Shares are not listed
     or admitted to trading on any national securities  exchange,  the last
     sale price as reported by The Nasdaq  Stock Market  ("Nasdaq")  or, if
     the  Common  Shares  are not  listed or  admitted  to  trading  on any
     national securities exchange and sale prices for Common Shares are not
     reported by Nasdaq,  the last quoted  price or, if not so quoted,  the
     average of the high bid and low asked  prices in the  over-the-counter
     market as reported by Nasdaq or such other  system then in use, or, if
     on any  such  date  the  Common  Shares  are not  quoted  by any  such
     organization,  the  average  of the  closing  bid and asked  prices as
     furnished by a professional market maker making a market in the Common
     Shares  selected by the Board of  Directors.  The term  "Trading  Day"
     shall mean a day on which the principal national  securities  exchange
     on which the Common  Shares are listed or  admitted to trading is open
     for the  transaction  of  business  or, if the  Common  Shares are not
     listed or admitted to trading on any national securities  exchange,  a
     Business Day.

                    (ii) For the purpose of any computation hereunder,  the
     "current  per share  market  price" of the  Preferred  Shares shall be
     determined  in the same manner as set forth above for Common Shares in
     Section  11(d)(i).  If the  current  per  share  market  price  of the
     Preferred  Shares cannot be determined in the manner  provided  above,
     the "current per share market price" of the Preferred  Shares shall be
     conclusively  deemed to be the current per share  market  price of the
     Common  Shares  (appropriately  adjusted to reflect  any stock  split,
     stock dividend, subdivision, combination, reclassification, or similar
     transaction occurring after the date hereof) multiplied by 1,000.

                    (iii) If neither  the Common  Shares nor the  Preferred
     Shares are  publicly  held or so listed or traded,  "current per share
     market  price"  shall mean the fair value per share as  determined  in
     good faith by the Board of  Directors  based upon such  appraisals  or
     valuation  reports  of  such  independent  experts  as  the  Board  of
     Directors shall in good faith determine appropriate.



                                   - 15 -

<PAGE>



     Any such  determination  of "current per share market  price" shall be
     described in a statement filed with the Rights Agent.

               (e) No  adjustment  in the Purchase  Price shall be required
     unless  such  adjustment  would  require an increase or decrease of at
     least 1 percent in the Purchase  Price;  provided,  however,  that any
     adjustments  which by reason of this Section 11(e) are not required to
     be made  shall be  carried  forward  and  taken  into  account  in any
     subsequent adjustment. All calculations under this Section 11 shall be
     made to the nearest cent or to the nearest 1/100,000 of a Common Share
     or other share or  1/100,000,000  of a Preferred Share as the case may
     be.

               (f) If,  as a  result  of an  adjustment  made  pursuant  to
     Section  11(a) or Section  13(a),  the holder of any Right  thereafter
     exercised shall become entitled to receive any shares of capital stock
     of the Company other than Preferred  Shares,  the number of such other
     shares so  receivable  upon  exercise of any Right shall be subject to
     adjustment  from  time to time in a  manner  and on  terms  as  nearly
     equivalent  as  practicable  to the  provisions  with  respect  to the
     Preferred  Shares  contained in this Section 11 and the  provisions of
     Sections  7, 9, 10, 13 and 14 hereof  with  respect  to the  Preferred
     Shares shall apply on like terms to any such other shares.

               (g) All Rights originally  issued by the Company  subsequent
     to any adjustment  made to the Purchase Price hereunder shall evidence
     the right to purchase,  at the adjusted  Purchase Price, the number of
     1/1,000s of a Preferred Share  purchasable from time to time hereunder
     upon  exercise of the Rights,  all  subject to further  adjustment  as
     provided herein.

               (h) Unless the Company shall have  exercised its election as
     provided in Section 11(i) below,  upon each adjustment of the Purchase
     Price as a result of the calculations  made in Sections 11(b) and (c),
     each  Right  outstanding  immediately  prior  to the  making  of  such
     adjustment  shall  thereafter  evidence the right to purchase,  at the
     adjusted  Purchase Price, that number of 1/1,000s of a Preferred Share
     (calculated  to  the  nearest  1/100,000,000  of  a  Preferred  Share)
     obtained by (i)  multiplying (x) the number of 1/1,000s of a Preferred
     Share covered by a Right  immediately  prior to such adjustment by (y)
     the Purchase Price in effect  immediately  prior to such adjustment of
     the  Purchase  Price and (ii)  dividing the product so obtained by the
     Purchase  Price in effect  immediately  after such  adjustment  of the
     Purchase Price.

               (i) The  Company  may  elect,  on or  after  the date of any
     adjustment  of the  Purchase  Price,  to adjust  the  number of Rights
     instead of making any  adjustment  in the number of  Preferred  Shares
     purchasable  upon  the  exercise  of  a  Right.  Each  of  the  Rights
     outstanding after such adjustment



                                   - 16 -

<PAGE>



     of the  number  of  Rights  shall be  exercisable  for the  number  of
     1/1,000s  of a  Preferred  Share  for  which a Right  was  exercisable
     immediately prior to such adjustment.  Each Right held of record prior
     to such adjustment of the number of Rights shall become that number of
     Rights (calculated to the nearest 1/100,000)  obtained by dividing the
     Purchase Price in effect  immediately  prior to such adjustment of the
     Purchase Price by the Purchase Price in effect  immediately after such
     adjustment  of the  Purchase  Price.  The Company  shall make a public
     announcement   of  its  election  to  adjust  the  number  of  Rights,
     indicating  the record date for the  adjustment,  and, if known at the
     time, the amount of the adjustment to be made. This record date may be
     the  date  on  which  the  Purchase  Price  is  adjusted  or  any  day
     thereafter,  but, if the Right Certificates have been issued, shall be
     at least ten days after the date of the public announcement.  If Right
     Certificates  have been issued,  upon each adjustment of the number of
     Rights pursuant to this Section 11(i),  the Company shall, as promptly
     as practicable,  cause to be distributed to holders of record of Right
     Certificates  on  such  record  date  Right  Certificates  evidencing,
     subject  to Section 14  hereof,  the  additional  Rights to which such
     holders shall be entitled as a result of such  adjustment,  or, at the
     option of the Company,  shall cause to be  distributed to such holders
     of record in substitution  and replacement for the Right  Certificates
     held  by such  holders  prior  to the  date of  adjustment,  and  upon
     surrender thereof, if required by the Company,  new Right Certificates
     evidencing  all the Rights to which  such  holders  shall be  entitled
     after such adjustment.  Right  Certificates so to be distributed shall
     be issued,  executed  and  countersigned  in the manner  provided  for
     herein  (and may bear,  at the  option of the  Company,  the  adjusted
     Purchase Price) and shall be registered in the names of the holders of
     record of Right  Certificates  on the  record  date  specified  in the
     public announcement.

               (j) Irrespective of any adjustment or change in the Purchase
     Price or the number of 1/1,000s of a Preferred Share issuable upon the
     exercise  of  the  Rights,  as  applicable,   the  Right  Certificates
     theretofore and thereafter issued may continue to express the Purchase
     Price per 1/1,000 of a Preferred  Share and the number of shares which
     were expressed in the initial Right Certificates issued hereunder.

               (k) Before  taking any action that would cause an adjustment
     reducing the Purchase  Price below  1/1,000 of the then par value,  if
     any, of the Preferred Shares issuable upon exercise of the Rights, the
     Company  shall take any  corporate  action which may, in the advice or
     opinion of its  counsel,  be  necessary  in order that the Company may
     validly and legally issue fully paid and  nonassessable  1/1,000s of a
     Preferred Share at such adjusted Purchase Price.




                                   - 17 -

<PAGE>



               (l) In any case in which this Section 11 shall  require that
     an adjustment in the Purchase  Price be made  effective as of a record
     date for a specified event, the Company may elect to defer,  until the
     occurrence  of such  event,  the  issuance  to the holder of any Right
     exercised after such record date the number of 1/1,000s of a Preferred
     Share and other capital  stock or  securities of the Company,  if any,
     issuable upon such exercise over and above the number of 1/1,000s of a
     Preferred  Share and other capital stock or securities of the Company,
     if any, issuable upon such exercise on the basis of the Purchase Price
     in  effect  prior  to such  adjustment;  provided,  however,  that the
     Company shall  deliver to such holder a due bill or other  appropriate
     instrument  evidencing  such holder's right to receive such additional
     shares upon the occurrence of the event requiring such adjustment.

               (m)   Anything   in  this   Section   11  to  the   contrary
     notwithstanding,  the Company  shall be entitled to make such  further
     adjustments  in the number of 1/1,000s of a Preferred  Share which may
     be acquired upon exercise of the Rights,  and such  adjustments in the
     Purchase Price, in addition to those adjustments expressly required by
     this  Section 11, as and to the extent that the Board of  Directors in
     their sole  discretion  shall  determine to be advisable in order that
     any (i)  consolidation  or subdivision of the Preferred  Shares,  (ii)
     issuance  wholly  for cash of any  Preferred  Shares  at less than the
     current  market  price,  (iii)  issuance  wholly for cash of Preferred
     Shares or  securities  which by their  terms are  convertible  into or
     exchangeable for Preferred Shares,  (iv) dividends on Preferred Shares
     payable in  Preferred  Shares or (v)  issuance  of rights,  options or
     warrants  referred to in Section 11(b),  hereafter made by the Company
     to  holders  of its  Preferred  Shares  shall not be  taxable  to such
     holders or shall reduce the taxes payable by such holders.

               (n)  The   Company   shall  not,   at  any  time  after  the
     Distribution Date, (i) consolidate with any other Person (other than a
     Subsidiary of the Company in a transaction which complies with Section
     11(o) hereof),  (ii) merge with or into any other Person (other than a
     Subsidiary of the Company in a transaction which complies with Section
     11(o) hereof),  (iii) consummate a statutory plan of exchange with any
     other Person  (other than a Subsidiary of the Company in a transaction
     which  complies with Section 11(o)  hereof),  or (iv) sell or transfer
     (or permit any Subsidiary to sell or transfer), in one transaction, or
     a series of  transactions,  assets or earning power  aggregating  more
     than 50 percent of the assets or earning  power of the Company and its
     Subsidiaries  (taken as a whole) to any other Person or Persons (other
     than  the  Company  and/or  any of  its  Subsidiaries  in one or  more
     transactions each of which complies with Section 11(o) hereof), if (A)
     at the  time  of or  immediately  after  such  consolidation,  merger,
     consummation  or  sale  there  are  any  rights,   warrants  or  other
     instruments  or securities  outstanding  or agreements in effect which
     would substantially



                                   - 18 -

<PAGE>



     diminish or otherwise  eliminate the benefits  intended to be afforded
     by the  Rights  or (B) prior to,  simultaneously  with or  immediately
     after such  consolidation,  merger,  consummation  or sale, the Person
     which  constitutes,  or would  constitute,  the "Principal  Party" for
     purposes of Section 13(a) hereof shall have  distributed  or otherwise
     transferred to its  shareholders,  or other Persons  holding an equity
     interest in such Person, Rights previously owned by such Person or any
     of its Affiliates or Associates; provided, however, this Section 11(n)
     shall not  affect  the  ability of any  Subsidiary  of the  Company to
     consolidate  with, merge with or into,  consummate a statutory plan of
     exchange  with,  or sell or transfer  assets or earning  power to, any
     other Subsidiary of the Company.

               (o) After the  Distribution  Date,  the  Company  shall not,
     except as permitted  by Sections 23 or 24 hereof,  take (or permit any
     Subsidiary  to take) any action if at the time such action is taken it
     is reasonably foreseeable that such action will diminish substantially
     or otherwise  eliminate  the  benefits  intended to be afforded by the
     Rights,  including,  without limiting the generality of the foregoing,
     any  consolidation,  merger,  statutory  plan of  exchange  or sale or
     transfer of assets or earning power.

               (p)   Anything   in   this   Agreement   to   the   contrary
     notwithstanding, in the event that the Company shall at any time after
     the date of this  Agreement  and  prior to the  Distribution  Date (i)
     declare or pay a dividend on the outstanding  Common Shares payable in
     Common Shares,  (ii) subdivide the  outstanding  Common Shares,  (iii)
     combine the outstanding Common Shares into a smaller number of shares,
     or (iv) issue any shares of its capital stock in a reclassification of
     the outstanding  Common Shares,  the number of Rights  associated with
     each Common Share then outstanding,  or issued or delivered thereafter
     but prior to the Distribution Date, shall be proportionately  adjusted
     so that the number of Rights  thereafter  associated  with each Common
     Share following any such event  (including  other Common Shares issued
     after  the date of such  event,  but prior to the  Distribution  Date)
     shall equal the result  obtained by  multiplying  the number of Rights
     associated with each Common Share immediately prior to such event by a
     fraction  the  numerator  of which shall be the total number of Common
     Shares  outstanding  immediately  prior to the occurrence of the event
     and the  denominator  of which  shall be the  total  number  of Common
     Shares outstanding immediately following the occurrence of such event.

               Section 12.  Certificate of Adjusted  Purchase Price or Number of
Shares. Whenever an adjustment is made as provided in Sections 11 and 13 hereof,
the  Company  shall  (a)  promptly  prepare a  certificate  setting  forth  such
adjustment,  and a brief statement of the facts giving rise to such  adjustment,
(b)  promptly  file with the Rights Agent and with each  transfer  agent for the
Preferred Shares and the Common Shares a copy of such certificate and (c) mail a
brief summary thereof to each holder of a Right Certificate (or, if prior to the
Distribution



                                     - 19 -

<PAGE>



Date, to each holder of a certificate  representing Common Shares, provided that
no such summary need be mailed to such holders with respect to adjustments  made
pursuant to Section 11(p) prior to the  Distribution  Date) in  accordance  with
Section 25 hereof.  Notwithstanding the foregoing  sentence,  the failure of the
Company  to make such  certification  or give such  notice  shall not affect the
validity of or the force or effect of the requirement for such  adjustment.  Any
adjustment  to be made  pursuant to Sections 11 and 13 of this Rights  Agreement
shall be effective  as of the date of the event giving rise to such  adjustment.
The Rights Agent shall be fully protected in relying on any such certificate and
on any adjustment therein contained.

               Section 13. Consolidation,  Merger, Statutory Plan of Exchange or
Sale or Transfer of Assets or Earning Power.

               (a) In the event that, directly or indirectly,  after there is an
Acquiring  Person,  (i) the Company  shall  consolidate  with, or merge with and
into,  any other Person (other than a Subsidiary of the Company in a transaction
that  complies  with Section  11(o)  hereof),  and the Company  shall not be the
continuing or surviving  corporation of such  consolidation or merger,  (ii) any
Person (other than a Subsidiary of the Company in a transaction  which  complies
with Section 11(o) hereof) shall consolidate with the Company, or merge with and
into  the  Company  and  the  Company  shall  be  the  continuing  or  surviving
corporation of such merger and, in connection with such consolidation or merger,
all or part of the Common Shares shall be changed into or exchanged for stock or
other  securities  of the  Company  or of any other  Person or cash or any other
property,  (iii)  any  Person  (other  than a  Subsidiary  of the  Company  in a
transaction  that  complies  with Section  11(o)  hereof) shall acquire all or a
majority  of the Common  Shares of the Company  pursuant to a statutory  plan of
exchange,  or (iv) the Company shall sell or otherwise  transfer (or one or more
of  its  Subsidiaries  shall  sell  or  otherwise  transfer),  in  one  or  more
transactions  to any Person or  Persons  (other  than the  Company or any of its
wholly owned  Subsidiaries  in one or more  transactions  each of which complies
with Section 11(o)  hereof),  assets or earning power  aggregating  more than 50
percent of the  assets or  earning  power of the  Company  and its  Subsidiaries
(taken as a whole) (any event  described in clauses (i), (ii),  (iii) or (iv) of
this  Section  13(a) being a "Section 13 event"),  then,  and in each such case,
proper  provision  shall be made so that (A) each  holder of a Right,  except as
provided in Section 7(f)  hereof,  shall  thereafter  have the right to receive,
upon the exercise thereof at the then-current  Purchase Price in accordance with
the terms of this Agreement, such number of validly authorized and issued, fully
paid and  nonassessable  Common  Shares of the Principal  Party (as  hereinafter
defined)  which Common  Shares shall not be subject to any liens,  encumbrances,
rights of first refusal, transfer restrictions or other adverse claims, as shall
be equal to the result  obtained by (1) multiplying  the  then-current  Purchase
Price by the  number  of  1/1,000s  of a  Preferred  Share for which a Right was
exercisable immediately prior to the first occurrence of a Section 13 event (or,
if a  Section  11(a)(ii)  event  has  occurred  prior to the  Section  13 event,
multiplying  the  number  of such  1/1,000s  of a share  for  which a Right  was
exercisable  immediately prior to the first occurrence of such Section 11(a)(ii)
event  by  the  Purchase  Price  in  effect  immediately  prior  to  such  first
occurrence),  and  dividing  that  product by (2) 50 percent of the  current per
share market price  (determined in accordance  with Section 11(d) hereof) of the
Common  Shares  of such  Principal  Party  on the date of  consummation  of such
Section 13 event; (B) such Principal Party shall thereafter be liable for,



                                     - 20 -

<PAGE>



and shall assume,  by virtue of such  consolidation,  merger,  statutory plan of
exchange,  sale or  transfer,  all the  obligations  and  duties of the  Company
pursuant to this Agreement; (C) the term "Company" shall thereafter be deemed to
refer  to  such  Principal  Party,  it  being  specifically  intended  that  the
provisions of Section 11 hereof shall apply only to such  Principal  Party after
the first  occurrence of a Section 13 event; (D) such Principal Party shall take
such steps  (including,  but not limited  to, the  reservation  of a  sufficient
number of shares  of its  Common  Shares  in  accordance  with  Section 9 hereof
applicable  to the  reservation  of  capital  shares)  in  connection  with such
consummation  as may be  necessary  to assure that the  provisions  hereof shall
thereafter be  applicable,  as nearly as  reasonably  may be, in relation to the
shares of its Common  Shares  thereafter  deliverable  upon the  exercise of the
Rights;  and (E) the  provisions  of  Section  11(a)(ii)  hereof  shall be of no
further effect following the first occurrence of any Section 13 event.

               (b) "Principal Party" shall mean:

               (i) in the case of any transaction  described in clause (i),
     (ii) or (iii) of Section  13(a)  hereof,  (A) the  Person  that is the
     issuer of any  securities  into which Common Shares of the Company are
     converted  in such  consolidation  or  merger  or for  which  they are
     exchanged in such  statutory  plan of  exchange,  or, if there is more
     than one such issuer, the issuer of Common Shares that has the highest
     aggregate  current market price (determined in accordance with Section
     11(d) hereof) and (B) if no securities are so issued,  the Person that
     is the other party to such consolidation,  merger or statutory plan of
     exchange,  or, if there is more than one such  Person,  the Person the
     Common Shares of which has the highest  aggregate current market price
     (determined in accordance with Section 11(d) hereof); and

               (ii) in the case of any transaction described in clause (iv)
     of Section  13(a) hereof,  the Person that is the party  receiving the
     largest portion of the assets or earning power transferred pursuant to
     such transaction or  transactions,  or, if each Person that is a party
     to such  transaction or transactions  receives the same portion of the
     assets or earning power  transferred  pursuant to such  transaction or
     transactions  or if the Person  receiving  the largest  portion of the
     assets or earning  power cannot be  determined,  whichever  Person the
     Common Shares of which has the highest  aggregate current market price
     (determined in accordance with Section 11(d) hereof);

provided,  however,  that in any such  case:  (A) if the  Common  Shares of such
Person are not at such time and have not been  continuously  over the  preceding
twelve-month period registered under Section 12 of the Exchange Act ("Registered
Common  Shares"),  or such  Person is not a  corporation,  and such  Person is a
direct or  indirect  Subsidiary  of another  Person that has  Registered  Common
Shares  outstanding,  "Principal Party" shall refer to such other Person; (B) if
the Common Shares of such Person are not Registered Common Shares or such Person
is not a corporation, and such Person is a direct or indirect Subsidiary of



                                   - 21 -

<PAGE>



another  Person but is not a direct or  indirect  Subsidiary  of another  Person
which has Registered Common Shares outstanding, "Principal Party" shall refer to
the ultimate  parent entity of such  first-mentioned  Person;  (C) if the Common
Shares of such Person are not  Registered  Common Shares or such Person is not a
corporation,  and such Person is directly or indirectly  controlled by more than
one Person,  and one or more of such other Persons has Registered  Common Shares
outstanding, "Principal Party" shall refer to whichever of such other Persons is
the issuer of the Registered  Common Shares having the highest aggregate current
market price  (determined in accordance  with Section 11(d) hereof);  and (D) if
the Common Shares of such Person are not Registered Common Shares or such Person
is not a  corporation,  and such Person is directly or indirectly  controlled by
more than one Person,  and none of such other  Persons  have  Registered  Common
Shares  outstanding,  "Principal Party" shall refer to whichever ultimate parent
entity is the corporation having the greatest shareholders' equity or, if no
such ultimate parent entity is a corporation,  shall refer to whichever ultimate
parent entity is the entity having the greatest net assets.

               (c) The  Company  shall not  consummate  any such  consolidation,
merger,  statutory plan of exchange,  sale or transfer  unless prior thereto the
Company and  Principal  Party shall have  executed  and  delivered to the Rights
Agent a supplemental  agreement  confirming that (i) such Principal Party shall,
upon consummation of such consolidation,  merger,  statutory plan of exchange or
sale or transfer of assets or earning power, assume this Agreement in accordance
with  Sections  13(a)  and (b)  hereof,  (ii) all  rights  of first  refusal  or
preemptive  rights in respect of the issuance of Common Shares of such Principal
Party upon exercise of outstanding Rights have been waived,  (iii) any provision
of the authorized  securities of such Principal Party or of its charter,  bylaws
or other  instruments  governing its corporate affairs which would obligate such
Principal  Party  to issue in  connection  with,  or as a  consequence  of,  the
consummation of a transaction referred to in Section 13(a) hereof, Common Shares
of such  Principal  Party at less than the  then-current  per share market price
(determined in accordance  with Section 11(d) hereof) or securities  exercisable
for, or convertible  into, such Common Shares at less than such then-current per
share market price (other than to the holders of Rights pursuant to this Section
13) have been waived or canceled,  and (iv) such transaction shall not result in
a default by such  Principal  Party under this  Agreement and further  providing
that,  as soon as  practicable  after  the  date of any  consolidation,  merger,
statutory  plan of  exchange  or sale or  transfer  of assets or  earning  power
referred to in Section 13(a) hereof, such Principal Party will:

               (A)  prepare  and file a  registration  statement  under the
     Securities   Act  with  respect  to  the  Rights  and  the  securities
     purchasable  upon exercise of the Rights on an  appropriate  form, use
     its best  efforts  to cause  such  registration  statement  to  become
     effective  as soon as  practicable  after such filing and use its best
     efforts to cause such registration statement to remain effective (with
     a prospectus at all times meeting the  requirements  of the Securities
     Act) until the Final  Expiration  Date of the  Rights,  and  similarly
     comply with applicable state securities laws;




                                   - 22 -

<PAGE>



               (B) use its best  efforts to list (or  continue  the listing
     of) the Rights and the  securities  purchasable  upon  exercise of the
     Rights on a national  securities  exchange or to meet the  eligibility
     requirements for quotation on Nasdaq or such other system then in use;
     and

               (C)  deliver to holders of the Rights  historical  financial
     statements for such Principal  Party which comply in all respects with
     the  requirements  for registration on Form 10 (or any successor form)
     under the Exchange Act.

In the event that at any time after the occurrence of a Section  11(a)(ii) event
hereof some or all of the Rights shall not have been  exercised at the time of a
Section 13 event,  the Rights which have not  theretofore  been exercised  shall
thereafter be  exercisable  in the manner  described in Section  13(a)  (without
taking into account any prior adjustment required by Section 11(a)(ii)).

               (d) The  provisions of this Section 13 shall  similarly  apply to
successive  consolidations,  mergers  or  plans  of  exchange  or sales or other
transfers.

               (e)  Notwithstanding  anything in this Agreement to the contrary,
Section 13 shall not be  applicable  to a  transaction  described in clause (i),
(ii) or (iii) of Section  13(a) hereof if (i) such  transaction  is  consummated
with a Person or Persons who acquired Common Shares of the Company pursuant to a
Qualifying  Offer (or a wholly owned  subsidiary of any such Person or Persons),
(ii) the price per Common Share offered in such transaction is not less than the
price per Common  Share paid to all holders of Common  Shares  whose shares were
purchased pursuant to such Qualifying Offer, and (iii) the form of consideration
being  offered  to the  remaining  holders  of Common  Shares  pursuant  to such
transaction  is the  same as the form of  consideration  paid  pursuant  to such
Qualifying Offer. Upon consummation of any such transaction contemplated by this
Section 13(e), all Rights hereunder shall expire.

               Section 14. Fractional Rights and Fractional Shares.

               (a) The  Company  shall not be  required  to issue  fractions  of
Rights or to distribute  Right  Certificates  which evidence  fractional  Rights
(i.e., Rights to acquire less than 1/1,000 of a Preferred Share). If the Company
shall determine not to issue such fractional Rights,  there shall be paid to the
registered  holders  of  the  Right  Certificates  with  regard  to  which  such
fractional  Rights would  otherwise be issuable,  an amount in cash equal to the
same fraction of the current market value of a whole Right.  For the purposes of
this  Section  14(a),  the  current  market  value of a whole Right shall be the
closing price of the Rights for the Trading Day immediately prior to the date on
which such  fractional  Rights would have been otherwise  issuable.  The closing
price for any day shall be the last sale price, regular way, or, in case no such
sale takes place on such day,  the average of the closing bid and asked  prices,
regular  way,  in  either  case  as  reported  in  the  principal   consolidated
transaction  reporting system with respect to securities listed on the principal
national  securities  exchange  on which the Rights are  listed or  admitted  to
trading or, if the Rights are not listed or admitted to trading on any  national
securities exchange, the last sale price as reported by Nasdaq or, if the Rights
are not listed or admitted to trading on any  national  securities  exchange and
sale prices for the Rights are not



                                     - 23 -

<PAGE>



reported by Nasdaq,  the last quoted price, or, if not so quoted, the average of
the high bid and low asked prices in the over-the-counter  market as reported by
Nasdaq or such other  system  then in use or, if on any such date the Rights are
not quoted by any such  organization,  the  average of the closing bid and asked
prices as furnished by a professional market maker making a market in the Rights
selected by the Board of Directors.  If on any such date no such market maker is
making a market in the Rights, the fair value of the Rights on such date will be
as  determined  in good  faith  by the  Board  of  Directors,  based  upon  such
appraisals  or  valuation  reports of such  independent  experts as the Board of
Directors shall in good faith determine appropriate.

               (b) The  Company  shall not be  required  to issue  fractions  of
Preferred  Shares (other than fractions which are integral  multiples of 1/1,000
of a Preferred Share) upon exercise of the Rights, or to distribute certificates
which  evidence  fractional  Preferred  Shares (other than  fractions  which are
integral  multiples  of 1/1,000 of a Preferred  Share).  Fractions  of Preferred
Shares in  integral  multiples  of 1/1,000  of a  Preferred  Share  may,  at the
election of the Company,  be evidenced by  depositary  receipts,  pursuant to an
appropriate  agreement  between  the Company  and a  depositary  selected by it,
provided that such agreement  shall provide that the holders of such  depositary
receipts shall have all the rights, privileges and preferences to which they are
entitled  as  beneficial  owners  of  the  Preferred  Shares.  With  respect  to
fractional  Preferred  Shares that are not  integral  multiples  of 1/1,000 of a
Preferred Share, if the Company does not issue  fractional  shares or depositary
receipts in lieu  thereof,  the Company shall pay to the  registered  holders of
Right  Certificates  at the time such Rights are exercised as herein provided an
amount in cash equal to the same  fraction  of the current  market  value of one
Preferred Share. For purposes of this Section 14(b), the current market value of
1/1,000  of a  Preferred  Share  shall  be  1/1,000  of the  closing  price of a
Preferred  Share (as determined in accordance with Section 11(d) hereof) for the
Trading Day immediately prior to the date of such exercise.

               (c) The  holder  of a Right,  by the  acceptance  of the  Rights,
expressly  waives his right to receive any  fractional  Rights or any fractional
shares upon exercise of a Right except as permitted by this Section 14.

               Section 15. Rights of Action.  All rights of action in respect of
this  Agreement,  excepting the rights of action given to the Rights Agent under
Section 18 hereof, are vested in the respective  registered holders of the Right
Certificates (and, prior to the Distribution Date, the registered holders of the
Common Shares); and any registered holder of any Right Certificate (or, prior to
the Distribution Date, of the Common Shares),  without the consent of the Rights
Agent  or of the  holder  of any  other  Right  Certificate  (or,  prior  to the
Distribution Date, of the Common Shares),  may in his own behalf and for his own
benefit,  enforce, and may institute and maintain any suit, action or proceeding
against  the Company to enforce,  or  otherwise  act in respect of, his right to
exercise the Rights  evidenced by such Right  Certificate in the manner provided
in such Right Certificate and in this Agreement.  Without limiting the foregoing
or  any  remedies  available  to  the  holders  of  Rights,  it is  specifically
acknowledged that the holders of Rights would not have an adequate remedy at law
for any breach of this Agreement and will be entitled to specific performance of
the  obligations  under,  and  injunctive  relief  against  actual or threatened
violations of, the obligations of any Person subject to this Agreement.



                                     - 24 -

<PAGE>




               Section 16. Agreement of Right Holders.  Every holder of a Right,
by accepting the same, consents and agrees with the Company and the Rights Agent
and with every other holder of a Right that:

               (a) prior to the  Distribution  Date,  the  Rights  shall be
     evidenced by the certificates for Common Shares registered in the name
     of the holders of the Common  Shares  (which  certificates  for Common
     Shares shall also constitute  certificates  for Rights) and each Right
     will be  transferable  only in  connection  with the  transfer  of the
     Common Shares;

               (b) after the Distribution  Date, the Right Certificates are
     transferable  only  on the  registry  books  of the  Rights  Agent  if
     surrendered at the principal office of the Rights Agent, duly endorsed
     or  accompanied  by a  proper  instrument  of  transfer  and  with the
     appropriate forms and certificates duly executed; and

               (c) subject to Sections  6(a) and 7(f)  hereof,  the Company
     and the  Rights  Agent may deem and treat the person in whose name the
     Right Certificate (or, prior to the Distribution  Date, the associated
     Common Shares certificate) is registered as the absolute owner thereof
     and of the Rights evidenced thereby  (notwithstanding any notations of
     ownership  or  writing  on the Right  Certificates  or the  associated
     Common Shares certificate made by anyone other than the Company or the
     Rights Agent) for all purposes whatsoever, and neither the Company nor
     the Rights Agent shall be affected by any notice to the contrary.

               Section  17.  Right  Holders  and Right  Certificate  Holders Not
Deemed a  Shareholder.  No holder,  as such,  of any Right or Right  Certificate
shall be entitled to vote,  receive  dividends  or be deemed for any purpose the
holder of the number of 1/1,000s of a Preferred Share or any other securities of
the  Company  which may at any time be  issuable  on the  exercise of the Rights
represented  thereby,  nor  shall  anything  contained  herein  or in any  Right
Certificate  be  construed  to  confer  upon the  holder  of any  Right or Right
Certificate,  as such,  any of the rights of a shareholder of the Company or any
right to vote for the  election of  directors  or upon any matter  submitted  to
shareholders  at any  meeting  thereof,  or to give or  withhold  consent to any
corporate  action,  or to receive notice of meetings or other actions  affecting
shareholders  (except as provided in Section  25),  or to receive  dividends  or
subscription  rights, or otherwise,  until the Right or Rights evidenced by such
Right  Certificate  shall have been exercised in accordance  with the provisions
hereof.

               Section 18. Concerning the Rights Agent.

               (a) The  Company  agrees to pay to the  Rights  Agent  reasonable
compensation  for all services  rendered by it hereunder and, from time to time,
on demand of the Rights  Agent,  its  reasonable  expenses  and counsel fees and
other  disbursements  incurred  in the  administration  and  execution  of  this
Agreement and the exercise and performance of its duties hereunder. The



                                     - 25 -

<PAGE>



Company also agrees to  indemnify  the Rights Agent for, and to hold it harmless
against, any loss, liability, or expense, incurred without negligence, bad faith
or willful  misconduct  on the part of the Rights  Agent,  for anything  done or
omitted by the Rights Agent in connection with the acceptance and administration
of this  Agreement,  including  the costs and expenses of defending  against any
claim of liability. Anything to the contrary notwithstanding,  in no event shall
the Rights Agent be liable for special,  indirect,  consequential  or incidental
loss or  damage  of any  kind  whatsoever  (including  but not  limited  to lost
profits),  even if the Rights Agent has been advised of the  likelihood  of such
loss or damage.

               (b) The  Rights  Agent  shall be  protected  and  shall  incur no
liability  for or in respect of any action  taken,  suffered or omitted by it in
connection with its  administration of this Agreement in reliance upon any Right
Certificate  or  certificate  for the  Preferred  Shares or Common Shares or for
other securities of the Company,  instrument of assignment or transfer, power of
attorney,   endorsement,   affidavit,   letter,  notice,   direction,   consent,
certificate,  statement, or other paper or document believed by it to be genuine
and to be signed,  executed and, where necessary,  verified or acknowledged,  by
the proper person or persons, or otherwise upon the advice of its counsel as set
forth in Section 20 hereof.

               Section 19. Merger or  Consolidation  or Change of Name of Rights
Agent.

               (a) Any  corporation or entity into which the Rights Agent or any
successor  Rights Agent may be merged or with which it may be  consolidated,  or
any corporation or entity  resulting from any merger or  consolidation  to which
the  Rights  Agent or any  successor  Rights  Agent  shall  be a  party,  or any
corporation  or  entity  succeeding  to the  corporate  trust or stock  transfer
business  of the  Rights  Agent  or any  successor  Rights  Agent,  shall be the
successor  to the Rights  Agent under this  Agreement  without the  execution or
filing of any paper or any further act on the part of any of the parties hereto,
provided that such  corporation or entity would be eligible for appointment as a
successor  Rights Agent under the  provisions  of Section 21 hereof.  If, at the
time such  successor  Rights Agent shall  succeed to the agency  created by this
Agreement,  any of the Right  Certificates shall have been countersigned but not
delivered, any such successor Rights Agent may adopt the countersignature of the
predecessor  Rights Agent and deliver such Right  Certificates so countersigned;
and  if at  that  time  any  of the  Right  Certificates  shall  not  have  been
countersigned,   any  successor   Rights  Agent  may   countersign   such  Right
Certificates  either in the name of the predecessor  Rights Agent or in the name
of the  successor  Rights Agent;  and in all such cases such Right  Certificates
shall  have  the full  force  provided  in the  Right  Certificates  and in this
Agreement.

               (b) If at any time the name of the Rights  Agent shall be changed
and at such time any of the Right Certificates shall have been countersigned but
not delivered,  the Rights Agent may adopt the countersignature  under its prior
name and deliver Right Certificates so countersigned; and if at that time any of
the Right Certificates shall not have been  countersigned,  the Rights Agent may
countersign such Right  Certificates  either in its prior name or in its changed
name;  and in all such cases such Right  Certificates  shall have the full force
provided in the Right Certificates and in this Agreement.




                                     - 26 -

<PAGE>



               Section 20. Duties of Rights Agent.  The Rights Agent  undertakes
the duties and  obligations  imposed by this Agreement upon the following  terms
and  conditions,  by  all  of  which  the  Company  and  the  holders  of  Right
Certificates, by their acceptance thereof, shall be bound:

               (a) The Rights Agent may consult with legal counsel (who may
     be legal counsel for the  Company),  and the advice or opinion of such
     counsel shall be full and complete authorization and protection to the
     Rights Agent as to any action taken or omitted by it in good faith and
     in accordance with such advice or opinion.

               (b)  Whenever in the  performance  of its duties  under this
     Agreement  the Rights Agent shall deem it necessary or desirable  that
     any fact or matter be proved or  established  by the Company  prior to
     taking or suffering any action hereunder,  such fact or matter (unless
     other evidence in respect thereof be herein  specifically  prescribed)
     may  be  deemed  to  be  conclusively  proved  and  established  by  a
     certificate  signed  by any  one of the  Chairman  of the  Board,  the
     President,  any Vice President,  the Treasurer or the Secretary of the
     Company and delivered to the Rights Agent; provided,  however, that so
     long as any Person is an Acquiring Person hereunder,  such certificate
     shall  be  signed  by a  majority  of  the  members  of the  Board  of
     Directors;  and such  certificate  shall be full  authorization to the
     Rights  Agent for any  action  taken or  suffered  in good faith by it
     under  the   provisions  of  this  Agreement  in  reliance  upon  such
     certificate.

               (c) The  Rights  Agent  shall  be  liable  hereunder  to the
     Company and any other  Person only for its own gross  negligence,  bad
     faith or willful misconduct.

               (d) The Rights Agent shall not be liable for or by reason of
     any of the statements of fact or recitals  contained in this Agreement
     or in the Right Certificates (except its countersignature  thereof) or
     be required to verify the same,  but all such  statements and recitals
     are and shall be deemed to have been made by the Company only.

               (e) The Rights Agent shall not be responsible in any respect
     for the  validity of this  Agreement  or the  execution  and  delivery
     hereof (except the due authorization, execution and delivery hereof by
     the Rights  Agent) or in respect for the  validity or execution of any
     Right Certificate (except its countersignature  thereof); nor shall it
     be  responsible  for any  breach by the  Company  of any  covenant  or
     condition contained in this Agreement or in any Right Certificate; nor
     shall it be responsible  for any change in the  exercisability  of the
     Rights  (including  the  Rights  becoming  null and void  pursuant  to
     Section 7(f) hereof) or any  adjustment  required under the provisions
     of Sections 11 or 13 hereof (including the manner, method or



                                   - 27 -

<PAGE>



     amount  thereof) or the  ascertaining  of the  existence of facts that
     would  require any such change or  adjustment  (except with respect to
     the exercise of Rights evidenced by Right  Certificates  after receipt
     by the Rights Agent of the certificate  describing any such adjustment
     as  contemplated  by  Section  12  hereof);  nor  shall  it by any act
     hereunder be deemed to make any  representation  or warranty as to the
     authorization  or  reservation  of any  Preferred  Shares to be issued
     pursuant to this  Agreement or any Right  Certificate or as to whether
     any Preferred  Shares will,  when issued,  be validly  authorized  and
     issued, fully paid and nonassessable.

               (f)  The  Company  agrees  that it  will  perform,  execute,
     acknowledge   and  deliver  or  cause  to  be   performed,   executed,
     acknowledged   and   delivered   all  such  further  and  other  acts,
     instruments and assurances as may reasonably be required by the Rights
     Agent for the  carrying out or  performing  by the Rights Agent of the
     provisions of this Agreement.

               (g) The Rights  Agent is hereby  authorized  and directed to
     accept  instructions  with  respect to the  performance  of its duties
     hereunder  from any one of the Chairman of the Board,  the  President,
     any Vice  President,  the  Secretary,  any Assistant  Secretary or the
     Treasurer of the Company,  and to apply to such officers for advice or
     instructions in connection with its duties, and it shall not be liable
     for any action  taken or  suffered  to be taken by it in good faith in
     accordance with instructions of any such officer;  provided,  however,
     that so long as any  Person  is an  Acquiring  Person  hereunder,  the
     Rights Agent shall accept such  instructions  and advice only from the
     Board of  Directors  and shall not be liable for any  action  taken or
     suffered  to be taken  by it in good  faith in  accordance  with  such
     instructions.   Any  application  by  the  Rights  Agent  for  written
     instructions  from the Company may, at the option of the Rights Agent,
     set forth in writing any action proposed to be taken or omitted by the
     Rights Agent under this  Agreement  and the date on and/or after which
     such action shall be taken or such omission  shall be  effective.  The
     Rights  Agent shall not be liable for any action taken by, or omission
     of, the Rights  Agent in  accordance  with a proposal  included in any
     such  application on or after the date  specified in such  application
     (which date shall not be less than five  Business  Days after the date
     any such  officer of the Company or, if there is an  Acquiring  Person
     hereunder,  a  majority  of the  members  of the  Board of  Directors,
     actually  receives  such  application,  unless  any such  officer or a
     majority of the members of the Board of Directors shall have consented
     in writing to an earlier date) unless, prior to taking any such action
     (or the effective  date in the case of an omission),  the Rights Agent
     shall  have  received   written   instructions  in  response  to  such
     application specifying the action to be taken or omitted.




                                   - 28 -

<PAGE>



               (h) The Rights Agent and any shareholder,  director, officer
     or  employee of the Rights  Agent may buy,  sell or deal in any of the
     Rights  or other  securities  of the  Company  or  become  pecuniarily
     interested in any  transaction in which the Company may be interested,
     or  contract  with or lend money to the  Company or  otherwise  act as
     fully and  freely as though it were not the  Rights  Agent  under this
     Agreement.  Nothing herein shall preclude the Rights Agent from acting
     in any other capacity for the Company or for any other legal entity.

               (i) The Rights  Agent may  execute and  exercise  any of the
     rights or powers  hereby  vested in it or perform  any duty  hereunder
     either itself or by or through its attorneys or agents, and the Rights
     Agent shall not be answerable  or  accountable  for any act,  default,
     neglect or misconduct of any such  attorneys or agents or for any loss
     to the  Company  resulting  from any such  act,  default,  neglect  or
     misconduct,  provided  that  reasonable  care  was  exercised  in  the
     selection and continued employment thereof.

               (j) No provision of this Agreement  shall require the Rights
     Agent to expend or risk its own funds or otherwise incur any financial
     liability in the  performance  of any of its duties or in the exercise
     of its rights  hereunder  if the Rights  Agent  shall have  reasonable
     grounds  for  believing  that  repayment  of such  funds  or  adequate
     indemnification  against  such  risk or  liability  is not  reasonably
     assured to it.

               (k) If, with respect to any Right Certificate surrendered to
     the Rights Agent for exercise or transfer,  the  certificate  included
     with the form of  assignment  or form of election to purchase,  as the
     case may be, has either not been completed, not signed or indicates an
     affirmative  response to clause 1 and/or 2 thereof,  the Rights  Agent
     shall not take any  further  action  with  respect  to such  requested
     exercise or transfer  without first  consulting  with the Company.  If
     such  certificate has been completed and signed,  the Rights Agent may
     assume without further inquiry that the Right Certificate is not owned
     by a person  described in Section 7(f) hereof and shall not be charged
     with any knowledge to the contrary.

               Section  21.  Change of Rights  Agent.  The  Rights  Agent or any
successor  Rights Agent may resign and be discharged  from its duties under this
Agreement  upon 30 days'  notice in writing  mailed to the  Company  and to each
transfer  agent of the  Common  Shares and  Preferred  Shares by  registered  or
certified  mail,  and to the  registered  holders of the Right  Certificates  by
first-class  mail.  The  Company  may remove the Rights  Agent or any  successor
Rights  Agent upon 30 days'  notice in  writing,  mailed to the Rights  Agent or
successor  Rights Agent,  as the case may be, and to each transfer  agent of the
Common Shares and Preferred  Shares by registered or certified  mail, and to the
registered  holders of the Right Certificates by first-class mail. If the Rights
Agent shall resign or be removed or shall otherwise  become incapable of acting,
the Company shall appoint a successor to the Rights Agent. If the Company



                                     - 29 -

<PAGE>



shall  fail to make such  appointment  within a period of 30 days  after  giving
notice  of such  removal  or after  it has  been  notified  in  writing  of such
resignation or incapacity by the resigning or  incapacitated  Rights Agent or by
the holder of a Right Certificate (who shall, with such notice, submit his Right
Certificate  for  inspection by the Company),  then the Company shall become the
Rights Agent and the registered holder of any Right Certificate may apply to any
court of competent  jurisdiction  for the appointment of a new Rights Agent. Any
successor  Rights  Agent,  whether  appointed by the Company or by such a court,
shall be either (A) a corporation  or other entity  organized and doing business
under the laws of the United States or any state,  in good  standing,  having an
office in the state of New York which is authorized to exercise  corporate trust
or stock transfer powers and is subject to supervision or examination by federal
or state  authority and which has at the time of its appointment as Rights Agent
a combined  capital and surplus of at least $50 million or (B) an  Affiliate  of
such a  corporation.  After  appointment,  the  successor  Rights Agent shall be
vested with the same powers,  rights,  duties and  responsibilities as if it had
been  originally  named as Rights  Agent  without  further act or deed;  but the
predecessor  Rights  Agent shall  deliver and transfer to the  successor  Rights
Agent any property at the time held by it hereunder, and execute and deliver any
further assurance,  conveyance, act or deed necessary for the purpose. Not later
than the effective date of any such  appointment,  the Company shall file notice
thereof in writing with the predecessor  Rights Agent and each transfer agent of
the Common Shares and Preferred Shares,  and mail a notice thereof in writing to
the  registered  holders of the Right  Certificates.  Failure to give any notice
provided  for in this  Section 21,  however,  or any defect  therein,  shall not
affect the  legality  or validity  of the  resignation  or removal of the Rights
Agent or the appointment of the successor Rights Agent, as the case may be.

               Section 22. Issuance of New Right  Certificates.  Notwithstanding
any of the  provisions of this  Agreement or of the Rights to the contrary,  the
Company may, at its option,  issue new Right  Certificates  evidencing Rights in
such form as may be approved by the Board of Directors to reflect any adjustment
or change  in the  Purchase  Price per share and the  number or kind or class of
shares or other securities or property  purchasable under the Right Certificates
made in  accordance  with the  provisions  of this  Agreement.  In addition,  in
connection  with the issuance or sale of Common Shares of the Company  following
the  Distribution  Date and prior to the close of business on the earlier of the
Redemption  Date or the Final  Expiration  Date,  the  Company  (a) shall,  with
respect  to Common  Shares of the  Company  so  issued or sold  pursuant  to the
exercise of stock options or under any Plan, or upon the exercise, conversion or
exchange of securities  hereinafter  issued by the Company,  and (b) may, in any
other case, if deemed necessary or appropriate by the Board of Directors,  issue
Right  Certificates  representing the appropriate number of Rights in connection
with  such  issuance  or  sale;  provided,  however,  that  (i)  no  such  Right
Certificate  shall be issued if, and to the extent  that,  the Company  shall be
advised  by  counsel  that such  issuance  would  create a  significant  risk of
material  adverse  tax  consequences  to the  Company or the Person to whom such
Right Certificate  would be issued,  and (ii) no such Right Certificate shall be
issued if, and to the extent that,  appropriate  adjustment shall otherwise have
been made in lieu of the issuance thereof.




                                     - 30 -

<PAGE>



               Section 23. Redemption.

               (a) The Company  may,  at its  option,  by action of the Board of
Directors  at any time prior to the earlier of (i) the 10th day after the Shares
Acquisition  Date or (ii) the close of  business on the Final  Expiration  Date,
redeem all, but not less than all, the then  outstanding  Rights at a redemption
price of $.01 per Right, as such amount may be appropriately adjusted to reflect
any stock split, stock dividend or similar transaction  occurring after the date
of this Agreement (such  redemption price being  hereinafter  referred to as the
"Redemption Price"). The Company may, at its option, pay the Redemption Price in
cash,  Common Shares of the Company (each share valued at the "current per share
market  price"  of a  common  share on the  Redemption  Date,  as such  price is
calculated  under Section 11(d)(i)  hereof),  or any other form of consideration
the Board of Directors deems appropriate.

               (b)  Immediately  upon  the  action  of the  Board  of  Directors
ordering the  redemption of the Rights,  or at such time and date  thereafter as
the Board of Directors may specify,  and without any further  action and without
any notice,  the right to exercise the Rights will  terminate and the only right
thereafter  of the holders of Rights shall be to receive the  Redemption  Price.
Promptly  after the action of the Board of Directors  ordering the redemption of
the Rights,  the Company shall give notice of such  redemption to the holders of
the then outstanding  Rights by mailing such notice to all such holders at their
last  addresses as they appear upon the  registry  books of the Rights Agent or,
prior to the Distribution  Date, on the registry books of the transfer agent for
the Common  Shares.  Any notice  which is mailed in the manner  herein  provided
shall be deemed given,  whether or not the holder receives the notice. Each such
notice  of  redemption  will  state  the  method  by which  the  payment  of the
Redemption Price will be made.  Neither the Company nor any of its Affiliates or
Associates  may redeem,  acquire or purchase  for value any Rights in any manner
other than that  specifically  set forth in this  Section  23, and other than in
connection with the purchase of Common Shares prior to the Distribution Date.

               Section 24. Exchange.

               (a) The Company  may,  at its  option,  by action of the Board of
Directors,  at any time after any Person becomes an Acquiring  Person,  exchange
all or part of the  then-outstanding  and  exercisable  Rights  (which shall not
include  Rights that have become void pursuant to the provisions of Section 7(f)
hereof) for Common  Shares at an exchange  ratio of one Common  Share per Right,
appropriately  adjusted to reflect any stock  split,  stock  dividend or similar
transaction  occurring  after the date hereof (such  exchange ratio being herein
referred to as the "Exchange Ratio").  Notwithstanding the foregoing,  the Board
of Directors  shall not be  empowered to effect such  exchange at any time after
any Person (other than the Company,  any Subsidiary of the Company,  any Plan of
the Company or of a Subsidiary  of the  Company,  or any Person  holding  Common
Shares  for or  pursuant  to the  terms of any  such  Plan),  together  with all
Affiliates  and Associates of such Person,  becomes the  Beneficial  Owner of 50
percent or more of the Common Shares then outstanding.




                                     - 31 -

<PAGE>



               (b)  Immediately  upon  the  action  of the  Board  of  Directors
ordering  the exchange of any Rights  pursuant to Section  24(a) and without any
further  action and without any notice,  the right to exercise such Rights shall
terminate  and the only right  thereafter of a holder of such Rights shall be to
receive that number of Common  Shares equal to the number of such Rights held by
such holder  multiplied by the Exchange  Ratio.  The Company shall promptly give
public notice of any such exchange; provided, however, that the failure to give,
or any defect in, such notice  shall not affect the  validity of such  exchange.
The  Company  promptly  shall mail a notice of any such  exchange  to all of the
holders of such Rights at their last  addresses as they appear upon the registry
books of the  Rights  Agent.  Any notice  which is mailed in the  manner  herein
provided shall be deemed given,  whether or not the holder  receives the notice.
Each such notice of exchange  will state the method by which the exchange of the
Common  Shares for Rights  will be  effected  and,  in the event of any  partial
exchange,  the number of Rights which will be  exchanged.  Any partial  exchange
shall be  effected  pro rata based on the number of Rights  (other  than  Rights
which have become void  pursuant to the  provisions of Section 7(f) hereof) held
by each holder of Rights.

               (c) In any exchange pursuant to this Section 24, the Company may,
at its option,  substitute  Preferred Shares (or equivalent preferred shares, as
such term is defined in Section 11(b) hereof) for Common Shares exchangeable for
Rights,  at the initial rate (as of the date of this  Agreement) of 1/1,000 of a
Preferred  Share (or  equivalent  preferred  share) for each  Common  Share,  as
appropriately  adjusted to reflect  subsequent  adjustments in the rights of the
Preferred  Shares  pursuant  to the terms  thereof,  so that the  fraction  of a
Preferred  Share  delivered  in lieu of each  Common  Share  shall have the same
rights to vote on the affairs of the Company, as does one Common Share.

               (d) The  Company  shall not be  required  to issue  fractions  of
Common Shares or to distribute  certificates  which evidence  fractional  Common
Shares.  In  lieu  of such  fractional  shares,  the  Company  shall  pay to the
registered  holders  of  the  Right  Certificates  with  regard  to  which  such
fractional  shares  would  otherwise  be issuable an amount in cash equal to the
same  fraction of the current  market  value of a whole  Common  Share.  For the
purposes of this Section 24(d),  the current market value of a whole share shall
be the closing  price of a Common  Share  determined  in the manner set forth in
Section 11(d) hereof.

               Section 25. Notice of Certain Events.

               (a) In case the  Company  shall  propose,  at any time  after the
Distribution  Date,  (i) to declare or pay any dividend  payable in stock of any
class to the holders of its Preferred  Shares or to make any other  distribution
to the holders of its  Preferred  Shares  (other than a regular  quarterly  cash
dividend),  or (ii) to offer to the  holders of its  Preferred  Shares  options,
rights or warrants to  subscribe  for or to purchase  any  additional  Preferred
Shares  or  shares  of stock of any  class or any  other  securities,  rights or
options, or (iii) to effect any  reclassification of its Preferred Shares (other
than a reclassification  involving only the subdivision of outstanding Preferred
Shares),  or (iv) to effect  any  consolidation  or merger  into or with,  or to
effect any exchange of the Common Shares of the Company  pursuant to a statutory
plan of exchange with, or to effect any sale or other transfer (or to permit one
or more of its Subsidiaries to effect any



                                     - 32 -

<PAGE>



sale or other transfer), in one or more transactions, of more than 50 percent of
the assets or earning  power of the  Company  and its  Subsidiaries  (taken as a
whole) to, any other Person or Persons (other than the Company and/or any of its
Subsidiaries  in one or more  transactions  each of which  complies with Section
11(o) hereof),  or (v) to effect the  liquidation,  dissolution or winding up of
the Company, then, in each such case, the Company shall give to each holder of a
Right  Certificate,  in  accordance  with  Section 26  hereof,  a notice of such
proposed  action,  which shall  specify the record date for the purposes of such
stock dividend, or distribution of rights or warrants, or the date on which such
reclassification,  consolidation, merger, exchange, sale, transfer, liquidation,
dissolution or winding up is to take place and the date of participation therein
by the  holders  of record of the  Preferred  Shares,  if any such date is to be
fixed,  and such notice  shall be so given in the case of any action  covered by
clause  (i) or (ii)  above  at  least  20 days  prior  to the  record  date  for
determining  holders of the Preferred Shares for purposes of such action, and in
the case of any such  other  action,  at least 20 days  prior to the date of the
taking of such  proposed  action  or the date of  participation  therein  by the
holders of the Preferred Shares,  whichever shall be the earlier. The failure to
give notice  required by this Section 25 or any defect  therein shall not affect
the legality or validity of the action taken by the Company or the vote upon any
such action.

               (b) In case any Section 11(a)(ii) event shall occur, then (i) the
Company shall as soon as practicable  thereafter  give to each holder of a Right
Certificate, in accordance with Section 26 hereof, a notice of the occurrence of
such event,  which shall specify the event and the  consequences of the event to
holders of Rights under Section  11(a)(ii)  hereof,  and (ii) all  references in
Section 25(a) to Preferred Shares shall be deemed  thereafter to refer to Common
Shares and/or, if appropriate, other securities.

               Section  26.  Notices.  Notices  or  demands  authorized  by this
Agreement  to be given or made by the Rights Agent or by the holder of any Right
Certificate to or on the Company shall be sufficiently  given or made if sent by
first-class mail, postage prepaid,  addressed (until another address is filed in
writing with the Rights Agent) as follows:

                           Epitope, Inc.
                           8505 S.W. Creekside Place
                           Beaverton, Oregon  97008
                           Attention:  Corporate Secretary

Subject to the provisions of Section 21 hereof,  any notice or demand authorized
by this  Agreement  to be given or made by the  Company  or by the holder of any
Right Certificate to or on the Rights Agent shall be sufficiently  given or made
if sent by first-class mail,  postage prepaid,  addressed (until another address
is filed in writing  with the  Company)  to the  principal  office of the Rights
Agent as follows:

                           ChaseMellon Shareholder Services, L.L.C.
                           520 Pike Street, Suite 1220
                           Seattle, Washington 98101
                           Attn:  Dennis Treibel



                                     - 33 -

<PAGE>




Notices  or  demands  authorized  by this  Agreement  to be given or made by the
Company or the Rights Agent to the holder of any Right Certificate (or, if prior
to the  Distribution  Date, to the holder of  certificates  representing  Common
Shares  of the  Company)  shall  be  sufficiently  given  or  made  if  sent  by
first-class  mail,  postage prepaid,  addressed to such holder at the address of
such holder as shown on the registry books of the Company.

               Section 27. Supplements and Amendments.

               (a) Prior to the  occurrence of a Section  11(a)(ii)  event,  the
Company may by action of the Board of  Directors,  and the Rights Agent shall if
the Company so directs,  supplement or amend any provision of this  Agreement in
any manner without the approval of any holders of Common Shares.  From and after
the occurrence of a Section  11(a)(ii)  event,  the Company may by action of the
Board of Directors,  and the Rights Agent shall if directed by the Company, from
time to time,  supplement  or amend this  Agreement  without the approval of any
holders  of Right  Certificates  in order  (i) to cure  any  ambiguity,  (ii) to
correct or supplement any provision  contained  herein which may be defective or
inconsistent with any other provisions herein,  (iii) to shorten or lengthen any
time  period  herein  or (iv) to  change  or  supplement  any  other  provisions
hereunder  in any manner  which the Board of  Directors  may deem  necessary  or
desirable  so long as the  interests  of the  holders  of the  Rights  or  Right
Certificates (other than an Acquiring Person or any Affiliate or Associate of an
Acquiring  Person)  shall not be  materially  and  adversely  affected  thereby;
provided,  however,  this  Agreement  may  not be  supplemented  or  amended  to
lengthen, pursuant to clause (iii) of this sentence, (A) a time period governing
redemption of the Rights if the Rights are not then redeemable, or (B) any other
time period unless such lengthening is for the purpose of protecting,  enhancing
or  clarifying  the rights of,  and/or the  benefits  to, the  holders of Rights
(other than an  Acquiring  Person or any  Affiliate or Associate of an Acquiring
Person).  Upon the delivery of a certificate from an appropriate  officer of the
Company or, so long as any Person is an  Acquiring  Person  hereunder,  from the
Board of Directors, which states that the proposed supplement or amendment is in
compliance with the terms of this Section 27(a),  the Rights Agent shall execute
such supplement or amendment.  Prior to the Distribution  Date, the interests of
the  holders of Rights  shall be deemed  coincident  with the  interests  of the
holders of the Common Shares of the Company.

               (b) After the Distribution  Date and prior to the earliest of the
Redemption Date,  Exchange Date, or Final Expiration Date, the Company shall not
effect any amendment to the Articles of  Incorporation  respecting the Preferred
Shares which would  materially  and adversely  affect the rights,  privileges or
powers of the  Preferred  Shares,  without the prior  approval of the holders of
two-thirds or more of the then outstanding Rights.

               Section  28.  Certain  Covenants.  Subject  to Section 27 and the
other provisions of this Agreement:

               (a) no  adjustment  to the  Purchase  Price,  the  number of
     Preferred Shares or Common Shares or other securities, as the case may
     be (or fractions of a share),  for which a Right is exercisable or the
     number of Rights  outstanding  shall be made or be  effective  if such
     adjustment would



                                   - 34 -

<PAGE>



     have the effect of reducing or limiting  the  benefits  the holders of
     the Rights would have had absent such adjustment,  including,  without
     limitation,  the  benefits  under  Section  11(a)(ii)  and Section 13,
     unless the terms of this  Agreement are amended so as to preserve such
     benefits; and

               (b) the Company shall not, during any time when there exists
     an Acquiring  Person (i) sell or issue,  or permit any  Subsidiary  to
     sell or issue, to an Acquiring  Person,  or any Affiliate or Associate
     thereof, any rights,  options,  warrants or convertible  securities on
     terms similar to, or which  materially  adversely affect the value of,
     the  Rights,  or (ii)  sell or issue to an  Acquiring  Person,  or any
     Affiliate or Associate  thereof,  Preferred  Shares,  Common Shares or
     shares of any other  class of  capital  stock if such sale or issue is
     intended  to or would  materially  adversely  affect  the value of the
     Rights.

               Section 29. Successors.  All the covenants and provisions of this
Agreement  by or for the benefit of the  Company or the Rights  Agent shall bind
and inure to the benefit of their respective successors and assigns hereunder.

               Section 30. Benefits of This Agreement. Nothing in this Agreement
shall be  construed  to give to any Person  other than the  Company,  the Rights
Agent and the registered  holders of the Right  Certificates  (and, prior to the
Distribution  Date,  the Common  Shares of the  Company)  any legal or equitable
right, remedy or claim under this Agreement; but this Agreement shall be for the
sole and exclusive  benefit of the Company,  the Rights Agent and the registered
holders of the Right  Certificates  (and,  prior to the  Distribution  Date, the
Common Shares of the Company).

               Section 31.  Severability.  If any term,  provision,  covenant or
restriction  of this Agreement is held by a court of competent  jurisdiction  or
other  authority  to be invalid,  void or  unenforceable,  the  remainder of the
terms, provisions,  covenants and restrictions of this Agreement shall remain in
full force and effect and shall in no way be affected,  impaired or invalidated;
provided,  however,  that  notwithstanding  anything  in this  Agreement  to the
contrary, if any such term,  provision,  covenant or restriction is held by such
court  or  authority  to be  invalid,  void or  unenforceable  and the  Board of
Directors  determines  in its good faith  judgment  that  severing  the  invalid
language from this  Agreement  would  adversely  affect the purpose or effect of
this  Agreement  and the  Rights  shall  not then be  redeemable,  the  right of
redemption  set forth in Section  23 hereof  shall be  reinstated  and shall not
expire until the close of business on the tenth  Business Day following the date
of such determination by the Board of Directors.

               Section 32. Determinations and Actions by the Board of Directors,
etc. For all purposes of this Agreement, any calculation of the number of Common
Shares of the Company outstanding at any particular time, including for purposes
of determining the particular percentage of such outstanding shares of which any
Person  is the  Beneficial  Owner,  shall  be made in  accordance  with the last
sentence of Rule  13d-3(d)(1)(i) of the Exchange Act regulations as in effect on
the date hereof. Except as otherwise specifically provided herein, the Board of



                                     - 35 -

<PAGE>



Directors  shall have the  exclusive  power and  authority  to  administer  this
Agreement  and to  exercise  all rights and powers  specifically  granted to the
Board of Directors or to the Company, or as may be necessary or advisable in the
administration of this Agreement,  including,  without limitation, the right and
power (a) to interpret  the  provisions  of this  Agreement  and (b) to make all
determinations  deemed  necessary or advisable  for the  administration  of this
Agreement.  All such actions,  calculations,  interpretations and determinations
(including, for purposes of clause (ii) below, all omissions with respect to the
foregoing)  which are done or made by the Board of Directors in good faith shall
(i) be final,  conclusive  and binding on the  Company,  the Rights  Agent,  the
holders of the Rights and all other  parties,  and (ii) not subject the Board of
Directors or any member thereof to any liability to the holders of the Rights.

               Section  33.   Governing  Law.  This  Agreement  and  each  Right
Certificate  issued  hereunder  shall be deemed to be a contract  made under the
laws of the  state of  Oregon  and for all  purposes  shall be  governed  by and
construed in accordance  with the laws of such state  applicable to contracts to
be made and performed entirely within such state;  provided,  however,  that the
rights and  obligations of the Rights Agent  hereunder  shall be governed by the
laws of the state of New Jersey (or state of  incorporation  or  organization of
any successor Rights Agent).

               Section 34.  Counterparts.  This Agreement may be executed in any
number of counterparts and each of such  counterparts  shall for all purposes be
deemed to be an original,  and all such counterparts  shall together  constitute
but one and the same instrument.

               Section 35.  Descriptive  Headings.  Descriptive  headings of the
several  sections of this Agreement are inserted for convenience  only and shall
not  control or affect  the  meaning or  construction  of any of the  provisions
hereof.

               IN WITNESS WHEREOF, the parties hereto have caused this Agreement
to be duly executed as of the day and year first above written.

                          EPITOPE, INC.


                          By       /s/ John W. Morgan
                                   John W. Morgan, President and Chief Executive
                                   Officer



                         CHASEMELLON SHAREHOLDER SERVICES,
                         L.L.C.


                         By       /s/ Dennis Treibel
                                  Name:  DENNIS TREIBEL
                                  Title: ASSISTANT VICE PRESIDENT



                                     - 36 -

<PAGE>



                                    EXHIBIT A


                            ARTICLES OF AMENDMENT OF
                                       OF
                                  EPITOPE, INC.



               Pursuant to ORS 60.134, Epitope, Inc., an Oregon corporation (the
"Corporation"),  adopts the  following  Articles of Amendment for the purpose of
determining  the  terms of a series of shares  of its  Preferred  Stock,  no par
value:

               1. The name of the Corporation is: Epitope, Inc.

               2. The text of the amendment determining the terms of a series of
shares of Preferred  Stock,  no par value, of the Corporation is attached hereto
as Appendix I.

               3. The  amendment  was duly  adopted by the Board of Directors of
the Corporation on October 21, 1997.


Execution:                                           ---------------------------
                                                     Name:
                                                     Title:


Dated:  December --, 1997


Person to contact about this filing:                 Erich W. Merrill, Jr.
         (Telephone Number):                         (503) 224-5858



                                     A - 1

<PAGE>



                                   APPENDIX I



                     DESIGNATION OF TERMS OF SERIES A JUNIOR
                    PARTICIPATING CUMULATIVE PREFERRED STOCK,
                                  NO PAR VALUE,

                                       OF

                                  EPITOPE, INC.
                          ----------------------------


               RESOLVED that  pursuant to the  authority  vested in the Board of
Directors  of  Epitope,  Inc.  (the  "Corporation"),   in  accordance  with  the
provisions  of its  Articles of  Incorporation,  as amended  (the  "Articles  of
Incorporation"),  a series of the Preferred  Stock, no par value (the "Preferred
Stock"),  of the  Corporation  be,  and it  hereby  is,  created,  and  that the
designation  and amount thereof and the  preferences,  limitations  and relative
rights thereof are determined to be as follows:

               Section 1.  Designation  and  Amount.  The shares of such  series
shall be designated as Series A Junior Participating Cumulative Preferred Stock,
no par value, and the number of shares constituting such series shall be 30,000.
Such series is hereinafter referred to as the "Series A Preferred Stock."

               Section 2. Dividends and Distributions.

               (A) The  holders  of  shares  of  Series A  Preferred  Stock,  in
preference to the holders of Common Stock, no par value (the "Common Stock"), of
the Corporation and of any other junior stock which may be outstanding, shall be
entitled to receive,  when,  as and if declared by the Board of Directors out of
funds legally available for the purpose, (i) quarterly dividends payable in cash
on the first day of March, June,  September and December in each year (each such
date  being  referred  to  herein  as  a  "Quarterly  Dividend  Payment  Date"),
commencing on the first Quarterly Dividend Payment Date after the first issuance
of a share or fraction of a share of Series A Preferred  Stock, in an amount per
share (rounded to the nearest cent) equal to the greater of (a) $1.00 per share,
or (b) subject to the  provision for  adjustment  hereinafter  set forth,  1,000
times the  aggregate  per share  amount of all cash  dividends  declared  on the
Common Stock since the immediately preceding Quarterly Dividend Payment Date or,
with  respect to the first  Quarterly  Dividend  Payment  Date,  since the first
issuance of any share or fraction  of a share of Series A Preferred  Stock,  and
(ii) subject to the provision for adjustment  hereinafter  set forth,  quarterly
distributions  (payable in kind) on each Quarterly  Dividend  Payment Date in an
amount per share  equal to 1,000  times the  aggregate  per share  amount of all
noncash  dividends  or other  distributions  (other  than a dividend  payable in
shares of Common  Stock or a  subdivision  of the  outstanding  shares of Common
Stock, by


                                     A - 2

<PAGE>



reclassification  or  otherwise),   declared  on  the  Common  Stock  since  the
immediately  preceding  Quarterly  Dividend Payment Date, or with respect to the
first Quarterly  Dividend  Payment Date since the first issuance of any share or
fraction of a share of Series A Preferred  Stock.  In the event the  Corporation
shall at any time  after  October  21,  1997 (the  "Rights  Declaration  Date"),
declare or pay any dividend on Common Stock  payable in shares of Common  Stock,
or effect a subdivision  or  combination  or  consolidation  of the  outstanding
shares of Common  Stock (by  reclassification  or  otherwise)  into a greater or
lesser  number of shares of Common  Stock,  then in each such case the amount to
which holders of shares of Series A Preferred  Stock are entitled  under clauses
(i)(b) or (ii) of the preceding  sentence shall be adjusted by multiplying  such
amount by a fraction  the  numerator  of which is the number of shares of Common
Stock  outstanding  immediately after such event and the denominator of which is
the number of shares of Common Stock that were outstanding  immediately prior to
such event.

               (B)  The  Corporation  shall  declare  a  mandatory  dividend  or
distribution  on the  Series A  Preferred  Stock as  provided  in  Section  2(A)
immediately  after it declares a dividend or  distribution  on the Common  Stock
(other than a dividend payable in shares of Common Stock); provided that, in the
event no dividend or  distribution  shall have been declared on the Common Stock
during the period  between  any  Quarterly  Dividend  Payment  Date and the next
subsequent  Quarterly  Dividend Payment Date, a mandatory  dividend of $1.00 per
share on the Series A  Preferred  Stock  shall  nevertheless  be payable on such
subsequent Quarterly Dividend Payment Date.

               (C)  Dividends  shall  begin  to  accrue  and  be  cumulative  on
outstanding  shares of Series A  Preferred  Stock  from the  Quarterly  Dividend
Payment  Date  next  preceding  the  date of issue of such  shares  of  Series A
Preferred Stock,  unless the date of issue of such shares is prior to the record
date for the first Quarterly  Dividend  Payment Date, in which case dividends on
such  shares  shall begin to accrue  from the date of issue of such  shares,  or
unless the date of issue is a Quarterly Dividend Payment Date or is a date after
the record date for the determination of holders of shares of Series A Preferred
Stock  entitled  to  receive a  quarterly  dividend  and before  such  Quarterly
Dividend  Payment Date, in either of which events such dividends  shall begin to
accrue and be cumulative from such Quarterly  Dividend Payment Date. Accrued but
unpaid  dividends shall cumulate but shall not bear interest.  Dividends paid on
the shares of Series A Preferred  Stock in an amount less than the total  amount
of such  dividends  at the time  accrued  and  payable on such  shares  shall be
allocated pro rata on a  share-by-share  basis among all such shares at the time
outstanding.  The Board of Directors may fix a record date for the determination
of holders of shares of Series A Preferred  Stock entitled to receive payment of
a dividend or distribution declared thereon, which record date shall be not more
than 45 days prior to the date fixed for the payment thereof.

               Section  3.  Voting  Rights.  The  holders  of shares of Series A
Preferred Stock shall have the following voting rights:

               (A)  Subject to the  provision  for  adjustment  hereinafter  set
forth,  each share of Series A Preferred  Stock shall entitle the holder thereof
to 1,000 votes (and each  1/1,000 of a share of Series A  Preferred  Stock shall
entitle the holder  thereof to one vote) on all matters


                                     A - 3

<PAGE>



submitted to a vote of the  shareholders  of the  Corporation.  In the event the
Corporation  shall at any time after the Rights  Declaration Date declare or pay
any  dividend on Common  Stock  payable in shares of Common  Stock,  or effect a
subdivision or combination or consolidation of the outstanding  shares of Common
Stock (by  reclassification  or  otherwise)  into a greater or lesser  number of
shares of Common Stock,  then in each such case the number of votes per share to
which holders of shares of Series A Preferred  Stock were  entitled  immediately
prior to such event shall be adjusted by multiplying  such number by a fraction,
the  numerator  of which is the  number of shares  of Common  Stock  outstanding
immediately  after  such  event and the  denominator  of which is the  number of
shares of Common Stock that were outstanding immediately prior to such event.

               (B) Except as otherwise provided in the Articles of Incorporation
or herein or by law,  the holders of shares of Series A Preferred  Stock and the
holders  of shares of  Common  Stock  shall  vote  together  as one class on all
matters submitted to a vote of the shareholders of the Corporation.

               (C) Except as set forth  herein,  holders  of Series A  Preferred
Stock  shall  have no  special  voting  rights  and their  consent  shall not be
required  (except to the extent  they are  entitled  to vote as set forth in the
Articles of Incorporation or herein or by law) for taking any corporate action.

               Section 4. Certain Restrictions.

               (A)  Whenever   quarterly   dividends   or  other   dividends  or
distributions  payable on the Series A Preferred  Stock as provided in Section 2
are in  arrears,  thereafter  and until all  accrued  and unpaid  dividends  and
distributions,  whether or not declared,  on shares of Series A Preferred  Stock
outstanding shall have been paid in full, the Corporation shall not:

               (i)  declare  or  pay   dividends   on  or  make  any  other
     distributions  on any  shares of stock  ranking  junior  (either as to
     dividends  or upon  liquidation,  dissolution  or  winding  up) to the
     Series A Preferred Stock;

               (ii)  declare  or  pay   dividends  on  or  make  any  other
     distributions on any shares of stock ranking on a parity (either as to
     dividends  or upon  liquidation,  dissolution  or winding up) with the
     Series A Preferred Stock,  except dividends paid ratably on the Series
     A Preferred  Stock and all such parity  stock on which  dividends  are
     payable or in arrears in  proportion to the total amounts to which the
     holders of all such shares are then entitled;

               (iii)   redeem  or   purchase  or   otherwise   acquire  for
     consideration  shares  of  any  stock  ranking  junior  (either  as to
     dividends  or upon  liquidation,  dissolution  or  winding  up) to the
     Series A Preferred  Stock,  provided that the  Corporation  may at any
     time redeem,  purchase or otherwise  acquire shares of any such junior
     stock in exchange for shares of any stock of the



                                     A - 4

<PAGE>



     Corporation   ranking   junior   (either  as  to   dividends  or  upon
     dissolution,  liquidation  or winding  up) to the  Series A  Preferred
     Stock; or

               (iv)  purchase or otherwise  acquire for  consideration  any
     shares of Series A Preferred Stock, or any share of stock ranking on a
     parity with the Series A Preferred Stock,  except in accordance with a
     purchase offer made in writing or by publication (as determined by the
     Board of  Directors)  to all holders of such shares upon such terms as
     the Board of Directors,  after  consideration of the respective annual
     dividend  rates and  other  relative  rights  and  preferences  of the
     respective  series and  classes,  shall  determine  in good faith will
     result in fair and equitable  treatment among the respective series or
     classes.

                  (B) The  Corporation  shall not permit any  subsidiary  of the
Corporation  to purchase or otherwise  acquire for  consideration  any shares of
stock of the  Corporation  unless the  Corporation  could,  under  Section 4(A),
purchase or otherwise acquire such shares at such time and in such manner.

                  Section 5. Reacquired Shares. Any shares of Series A Preferred
Stock  purchased  or  otherwise  acquired  by  the  Corporation  in  any  manner
whatsoever shall be retired and canceled promptly after the acquisition thereof.
The  Corporation  shall take all such  action as is  necessary  so that all such
shares shall after their  cancellation  become authorized but unissued shares of
Preferred Stock,  without  designation as to series, and may be reissued as part
of a new series of Preferred Stock to be created by resolution or resolutions of
the Board of Directors,  subject to the conditions and  restrictions on issuance
set forth herein.

                  Section 6.  Liquidation,  Dissolution  or Winding Up. Upon any
liquidation, dissolution or winding up of the Corporation, no distribution shall
be made (A) to the  holders  of shares of stock  ranking  junior  (either  as to
dividends  or upon  liquidation,  dissolution  or  winding  up) to the  Series A
Preferred  Stock  unless,  prior  thereto,  the  holders  of  shares of Series A
Preferred  Stock shall have received the higher of (i) $1.00 per share,  plus an
amount equal to accrued and unpaid dividends and distributions thereon,  whether
or not declared,  to the date of such payment,  or (ii) an aggregate  amount per
share,  subject to the provision for adjustment  hereinafter set forth, equal to
1,000  times the  aggregate  amount to be  distributed  per share to  holders of
Common  Stock;  nor shall any  distribution  be made (B) to the holders of stock
ranking on a parity (either as to dividends or upon liquidation,  dissolution or
winding up) with the Series A Preferred Stock, except distributions made ratably
on the Series A Preferred Stock and all other such parity stock in proportion to
the total amounts to which the holders of all such shares are entitled upon such
liquidation,  dissolution or winding up. In the event the  Corporation  shall at
any time declare or pay any dividend on Common Stock payable in shares of Common
Stock,  or  effect  a  subdivision  or  combination  or   consolidation  of  the
outstanding  shares of Common Stock (by  reclassification  or otherwise)  into a
greater or lesser number of shares of Common  Stock,  then in each such case the
aggregate  amount to which  holders  of shares of Series A  Preferred  Stock are
entitled  under clause  (A)(ii) of the preceding  sentence  shall be adjusted by
multiplying  such amount by a fraction  the  numerator of which is the number



                                     A - 5

<PAGE>



of shares of Common  Stock  outstanding  immediately  after  such  event and the
denominator  of  which is the  number  of  shares  of  Common  Stock  that  were
outstanding immediately prior to such event.

               Section 7.  Consolidation,  Merger,  etc. In case the Corporation
shall  enter  into  any  consolidation,  merger,  statutory  plan  of  exchange,
combination  or other  transaction  in which  the  shares  of  Common  Stock are
exchanged for or changed into other stock or  securities,  cash and/or any other
property,  or  otherwise  changed,  then in any such case the shares of Series A
Preferred  Stock shall at the same time be similarly  exchanged or changed in an
amount per share (subject to the provision for adjustment hereinafter set forth)
equal to 1,000 times the aggregate amount of stock, securities,  cash and/or any
other  property  (payable in kind),  as the case may be, into which or for which
each share of Common Stock is changed or exchanged. In the event the Corporation
shall at any time declare or pay any dividend on Common Stock  payable in shares
of Common Stock, or effect a subdivision or combination or  consolidation of the
outstanding  shares of Common Stock (by  reclassification  or otherwise)  into a
greater or lesser number of shares of Common  Stock,  then in each such case the
amount set forth in the  preceding  sentence  with  respect to the  exchange  or
change of shares of Series A Preferred  Stock  shall be adjusted by  multiplying
such  amount by a  fraction  the  numerator  of which is the number of shares of
Common Stock  outstanding  immediately  after such event and the  denominator of
which is the number of shares of Common Stock that were outstanding  immediately
prior to such event.

               Section 8. No Redemption.  The shares of Series A Preferred Stock
shall not be redeemable.  Notwithstanding  the foregoing,  the  Corporation  may
acquire shares of Series A Preferred Stock in any other manner permitted by law,
the Articles of Incorporation or this amendment thereof.

               Section 9. Rank.  Unless  otherwise  provided in the  Articles of
Incorporation  or an  amendment  thereof  relating  to a  subsequent  series  of
Preferred  Stock of the  Corporation,  the Series A  Preferred  Stock shall rank
junior  to all  other  series  of the  Corporation's  Preferred  Stock as to the
payment of dividends and the distribution of assets on liquidation,  dissolution
or winding up, and senior to the Common Stock of the Corporation.

               Section 10. Amendment. The Articles of Incorporation shall not be
amended  in any  manner  which  would  materially  alter or change  the  powers,
preferences  or special  rights of the Series A Preferred  Stock so as to affect
them  adversely  without  the  affirmative  vote of the  holders  of at  least a
majority  of  the  outstanding  shares  of  Series  A  Preferred  Stock,  voting
separately as a class.

               Section 11.  Fractional  Shares.  Series A Preferred Stock may be
issued in 1/1,000s of a share or other  fractions of a share which shall entitle
the holder, in proportion to such holder's fractional shares, to exercise voting
rights, receive dividends,  participate in distributions and to have the benefit
of all other rights of holders of Series A Preferred Stock.



                                     A - 6

<PAGE>



                                    EXHIBIT B


                           [FORM OF RIGHT CERTIFICATE]

Certificate No. R---------------                             ------------ Rights


     NOT  EXERCISABLE  AFTER  --------------  ---,  ------,  OR  EARLIER IF
     REDEEMED OR  EXCHANGED.  THE RIGHTS ARE SUBJECT TO  REDEMPTION AT $.01
     PER RIGHT, AND ARE SUBJECT TO EXCHANGE,  ON THE TERMS SET FORTH IN THE
     RIGHTS AGREEMENT. UNDER CERTAIN CIRCUMSTANCES (SPECIFIED IN THE RIGHTS
     AGREEMENT),  RIGHTS  BENEFICIALLY  OWNED BY AN  ACQUIRING  PERSON  (AS
     DEFINED  IN THE RIGHTS  AGREEMENT)  OR ANY  SUBSEQUENT  HOLDER OF SUCH
     RIGHTS MAY BECOME NULL AND VOID. [THE RIGHTS REPRESENTED BY THIS RIGHT
     CERTIFICATE  ARE OR WERE  BENEFICIALLY  OWNED BY A  PERSON  WHO WAS OR
     BECAME  AN  ACQUIRING  PERSON  OR  AN  AFFILIATE  OR  ASSOCIATE  OF AN
     ACQUIRING PERSON (AS SUCH TERMS ARE DEFINED IN THE RIGHTS  AGREEMENT).
     THIS RIGHT CERTIFICATE AND THE RIGHTS  REPRESENTED  HEREBY ARE VOID IN
     THE CIRCUMSTANCES SPECIFIED IN THE RIGHTS AGREEMENT.]*

                             Right Certificate

                               EPITOPE, INC.


               This  certifies that , or registered  assigns,  is the registered
owner of the  number  of Rights  set forth  above,  each of which  entitles  the
registered owner thereof, subject to the terms, provisions and conditions of the
Rights  Agreement  dated as of  December  ---,  1997 (the  "Rights  Agreement"),
between Epitope,  Inc., an Oregon  corporation (the "Company"),  and ChaseMellon
Shareholder Services, L.L.C. (the "Rights Agent," which term shall include every
successor Rights Agent under the Rights Agreement), to purchase from the Company
at any time after the  Distribution  Date (as such term is defined in the Rights
Agreement)  and  prior to 5 p.m.  (New York City  time) on  --------------  ---,
- ------, at the office or agency of the Rights Agent or its successor  designated
for such  purpose,  1/1,000  of a fully  paid,  nonassessable  share of Series A
Junior  Participating  Cumulative  Preferred Stock, no par value (the "Preferred
Shares"),  of the Company, at a purchase price initially of $60 per 1/1,000 of a
Preferred Share (the "Purchase Price"),  upon presentation and surrender of this
Right Certificate with the Form of Election to Purchase and related  certificate
duly  executed.  The  purchase  price shall be paid

- --------
*    That portion of the legend in brackets shall be inserted only if applicable
     and shall replace the preceding sentence.



                                     B - 1

<PAGE>


by bank certified  check or cashier's check payable to the order of the Company.
As  provided  in the  Rights  Agreement,  the  Purchase  Price and the number of
Preferred  Shares  which  may be  purchased  upon  the  exercise  of the  Rights
evidenced by this Right  Certificate are subject to modification  and adjustment
upon the happening of certain events.

               This Right Certificate is subject to all of the terms, provisions
and conditions of the Rights Agreement,  which terms,  provisions and conditions
are hereby  incorporated herein by reference and made a part hereof and to which
Rights Agreement  reference is hereby made for a full description of the rights,
limitations  of rights,  obligations,  duties and  immunities  hereunder  of the
Rights Agent, the Company and the holders of the Right  Certificates.  Copies of
the  Rights  Agreement  are on file at the  principal  executive  offices of the
Company and are  available  from the Rights  Agent or the Company  upon  written
request.

               Upon the occurrence of certain  events  specified in Section 7(f)
of the Rights  Agreement,  if the Rights evidenced by this Right Certificate are
or were  beneficially  owned by an Acquiring Person or an Affiliate or Associate
of an Acquiring  Person (as such terms are defined in the Rights  Agreement) or,
under  certain  circumstances,  a  transferee  of  any  such  Acquiring  Person,
Affiliate  or  Associate,  such Rights shall become null and void and any holder
thereof  (whether or not such holder is an  Acquiring  Person or an Affiliate or
Associate of an Acquiring  Person)  shall  thereafter  have no right to exercise
such Rights.

               In certain circumstances  described in the Rights Agreement,  the
Rights  evidenced hereby may entitle the holder hereof to purchase capital stock
of an entity  other than the  Company or receive  cash or other  assets,  all as
prescribed in the Rights Agreement.

               This Right Certificate, with or without other Right Certificates,
upon  surrender at the office or agency of the Rights Agent  designated for such
purpose, may be exchanged for another Right Certificate or Right Certificates of
like tenor and date  evidencing  Rights equal to the aggregate  number of Rights
evidenced by the Right Certificate or Right  Certificates  surrendered.  If this
Right  Certificate  shall be exercised in part,  the holder shall be entitled to
receive upon surrender  hereof another Right  Certificate or Right  Certificates
for the number of whole Rights not  exercised.  Subject to the provisions of the
Rights  Agreement,  the Rights evidenced by this Right  Certificate may, but are
not required  to, be redeemed by the Company at a  redemption  price of $.01 per
Right, or be exchanged at the Company's  option for one Common Share, as defined
in the Rights Agreement.

               The Company may (but shall not be required  to) issue  fractional
Preferred  Shares  upon the  exercise  of any Right or Rights  evidenced  hereby
(other than  fractions  which are  integral  multiples of 1/1,000 of a Preferred
Share,  which may, at the  election of the Company,  be evidenced by  depositary
receipts),  and, in lieu thereof, a cash payment may be made, as provided in the
Rights Agreement.

               No holder of this Right  Certificate,  as such, shall be entitled
to vote or  receive  dividends  or be deemed for any  purpose  the holder of the
Preferred Shares or of any other securities of the Company which may at any time
be issuable on the exercise hereof,  nor shall


                                     B - 2

<PAGE>



anything contained in the Rights Agreement or herein be construed to confer upon
the holder hereof, as such, any of the rights of a shareholder of the Company or
any right to vote for the election of directors or upon any matter  submitted to
shareholders  at any  meeting  thereof,  or to give or  withhold  consent to any
corporate  action,  or to receive notice of meetings or other actions  affecting
shareholders  (except  as  provided  in the  Rights  Agreement),  or to  receive
dividends  or  subscription  rights,  or  otherwise,  until  the Right or Rights
evidenced by this Right Certificate shall have been exercised as provided in the
Rights Agreement.

               This Right  Certificate  shall not be valid or obligatory for any
purpose until it shall have been countersigned by the Rights Agent.

               WITNESS the  facsimile  signature  of the proper  officers of the
Company and its corporate seal. Dated as of ----------------------------.


ATTEST:                                 EPITOPE, INC.


- --------------------------------        By   -----------------------------------
Secretary                                    Title


Countersigned:


CHASEMELLON SHAREHOLDER SERVICES, L.L.C.


By   ----------------------------------
     Authorized Signature




                                     B - 3

<PAGE>



                   [FORM OF REVERSE SIDE OF RIGHT CERTIFICATE]


                               FORM OF ASSIGNMENT


                (To be executed by the registered holder if such
               holder desires to transfer the Right Certificate.)


        FOR VALUE RECEIVED --------------------------- hereby sells, assigns and
transfers unto -----------------------------------------------------------------
- -------------------------------------------------------------------------------
                  (Please print name and address of transferee)

- --------------------------------------------------------------------------------
this Right Certificate, together with all right, title and interest therein, and
does hereby  irrevocably  constitute  and  appoint  ----------------------------
Attorney,  to  transfer  the  within  Right  Certificate  on  the  books  of the
within-named Company, with full power of substitution.


Dated:    ----------------------------

                                             -----------------------------------
                                             Signature


Signature Guaranteed:

                                   Certificate

               The  undersigned  hereby  certifies by checking  the  appropriate
boxes that:

               (1) this Right Certificate [ ] is [ ] is not being sold, assigned
and transferred by or on behalf of a Person who is or was an Acquiring Person or
an  Affiliate  or  Associate  of any such  Acquiring  Person  (as such terms are
defined in the Rights Agreement); and



                                     B - 4

<PAGE>



               (2)  after  due  inquiry  and  to  the  best   knowledge  of  the
undersigned, the undersigned [ ] did [ ] did not acquire the Rights evidenced by
this Right  Certificate  from any Person who is, was or  subsequently  became an
Acquiring Person or an Affiliate or Associate of an Acquiring Person.

Dated:    ----------------------------
                                                      --------------------------
                                                      Signature

Signature Guaranteed:
                                     NOTICE

               The signature to the foregoing  Assignment and  Certificate  must
correspond  to the name as written  upon the face of this Right  Certificate  in
every particular, without alteration or enlargement or any change whatsoever.



                                     B - 5

<PAGE>



                          FORM OF ELECTION TO PURCHASE


                      (To be executed if holder desires to
                        exercise the Right Certificate.)


To:  EPITOPE, INC.

               The   undersigned   hereby   irrevocably   elects   to   exercise
- -------------------------------------------------  Rights  represented  by  this
Right Certificate to purchase the Preferred Shares issuable upon the exercise of
such Rights (or such other  securities  as may be issuable  upon exercise of the
Rights) and requests that  certificates for such Preferred Shares (or such other
securities) be issued in the name of and delivered to:

- -----------------------------------------------------------------------------
                         (Please print name and address)
- -----------------------------------------------------------------------------

Please insert social security or other identifying number: --------------------

               If such number of Rights shall not be all the Rights evidenced by
this Right  Certificate,  a new Right  Certificate for the balance  remaining of
such Rights shall be registered in the name of and delivered to:

- -----------------------------------------------------------------------------
                         (Please print name and address)
- -----------------------------------------------------------------------------

Dated      ----------------------------

                                                      --------------------------
                                                      Signature

Signature Guaranteed:





                                     B - 6

<PAGE>


                                   Certificate

               The  undersigned  hereby  certifies by checking  the  appropriate
boxes that:

               (1) the Rights  evidenced by this Right  Certificate  [ ] are [ ]
are  not  beneficially  owned  by an  Acquiring  Person  or an  Affiliate  or an
Associate thereof (as such terms are defined in the Rights Agreement); and

               (2)  after  due  inquiry  and  to  the  best   knowledge  of  the
undersigned, the undersigned [ ] did [ ] did not acquire the Rights evidenced by
this Right  Certificate  from any person who is, was or  subsequently  became an
Acquiring Person or an Affiliate or Associate of an Acquiring Person.

Dated:    ----------------------------       -----------------------------------
                                             Signature

Signature Guaranteed:



                                     NOTICE

               The  signatures in the foregoing Form of Election to Purchase and
Certificate  must  correspond to the name as written upon the face of this Right
Certificate in every particular, without alteration or enlargement or any change
whatsoever.




                                     B - 7



                 [FORM OF FACE OF CERTIFICATE FOR COMMON STOCK]

                                  EPITOPE, INC.

               INCORPORATED UNDER THE LAWS OF THE STATE OF OREGON


COMMON STOCK                                                        COMMON STOCK
Number PO --------------                                   -------------- Shares


CUSIP 294261 10 2

         SEE REVERSE FOR CERTAIN DEFINITIONS AND A STATEMENT AS TO THE
           RIGHTS, PREFERENCES, PRIVILEGES AND RESTRICTIONS ON SHARES.


                  This Certifies that-------------------------------------------
is the owner of ---------------------------------------------------------------,
FULLY PAID AND NONASSESSABLE SHARES OF THE COMMON STOCK WITHOUT PAR VALUE OF

                                  EPITOPE, INC.

Said shares are transferable  only on the books of the Corporation by the holder
or by duly authorized  agent,  attorney or  representative  upon proper proof of
succession or authority.  This Certificate is not valid until  countersigned and
registered by the Transfer Agent and Registrar.

                  IN WITNESS  WHEREOF,  the Corporation has caused the facsimile
seal of the  Corporation  and the facsimile  signatures  of its duly  authorized
officers to be affixed to this Certificate.

                  DATED: ----------------------------



- -----------------------------------    -----------------------------------------
Secretary                              President

(Corporate Seal)


                                      - 1 -
<PAGE>



COUNTERSIGNED AND REGISTERED:

CHASEMELLON SHAREHOLDER SERVICES, L.L.C.
TRANSFER AGENT AND REGISTRAR


BY-------------------------
   AUTHORIZED SIGNATURE


                [FORM OF REVERSE OF CERTIFICATE FOR COMMON STOCK]

                  The  Corporation  is  authorized  to issue  common  stock  and
preferred stock. The holder of this certificate may obtain from the Secretary of
the  Corporation,  upon the holder's  request and without charge, a statement of
the powers, designations,  preferences and relative, participating,  optional or
other  special  rights  of each  class  of stock  (or  series  thereof)  and the
qualifications, limitations or restrictions of such preferences and/or rights as
are established  from time to time, and the number of shares  constituting  each
class and series.

                  This certificate also evidences and entitles the holder hereof
to certain Rights as set forth in the Shareholder  Rights Plan of Epitope,  Inc.
(the "Plan"),  until  separate  certificates  for such Rights are issued.  Under
certain  circumstances,  as set forth in the Plan, such Rights will be evidenced
by separate  certificates  and will no longer be evidenced by this  certificate.
The terms of the  Plan,  a copy of which is on file at the  principal  executive
offices of Epitope, Inc., are hereby incorporated herein by reference.  Epitope,
Inc.,  shall mail or cause to be mailed to the holder of this certificate a copy
of the Plan  without  charge  promptly  following  receipt of a written  request
therefor. Under certain circumstances set forth in the Plan, Rights beneficially
owned by any Person who is, was or becomes an Acquiring  Person or any Affiliate
or Associate  thereof (as such terms are defined in the Plan) and any subsequent
holder of such Rights, may become null and void.

                  The following  abbreviations,  when used in the inscription on
the face of this certificate, shall be construed as though they were written out
in full according to applicable laws or regulations:

         TEN COM           --       as tenants in common
         TEN ENT           --       as tenants by the entireties
         JT TEN            --       as joint tenants with rights of survivorship
                                    and not as tenants in common

         UNIF TRAN MIN ACT --.........................Custodian.................
                                     (Cust)                          (Minor)
                             under Uniform Transfers to Minors Act .............
                                                                      (State)


                                      - 2 -
<PAGE>



         UNIF GIFT MIN ACT --.....................Custodian.....................
                                   (Cust)                          (Minor)
                              under Uniform Gifts to Minors Act ................
                                                                     (State)

Additional abbreviations may also be used though not in the above list.


                  For Value Received,  ---------------------------- hereby sell,
assign and transfer unto

PLEASE INSERT SOCIAL SECURITY OR
OTHER IDENTIFYING NUMBER OF ASSIGNEE
===========================================================

===========================================================


- --------------------------------------------------------------------------------
  (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE)

- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------Shares

of the  common  stock  represented  by the  within  Certificate,  and do  hereby
irrevocably constitute and appoint

- ------------------------------------------------------------------------Attorney
to transfer  the said stock on the books of the within  named  Corporation  with
full power of substitution in the premises.

Dated ----------------------------



                                   X--------------------------------------------


                                   X -------------------------------------------
                                      NOTICE: THE  SIGNATURE TO THIS  ASSIGNMENT
                                              MUST  CORRESPOND  WITH THE NAME AS
                                              WRITTEN   UPON  THE  FACE  OF  THE
                                              CERTIFICATE  IN EVERY  PARTICULAR,
                                              WITHOUT  ALTERATION OR ENLARGEMENT
                                              OR ANY CHANGE WHATEVER



                                      - 3 -

<PAGE>




SIGNATURE(S) GUARANTEED:



- ----------------------------------------
THIS  SIGNATURE(S) MUST BE GUARANTEED BY
AN   ELIGIBLE   GUARANTOR    INSTITUTION
(BANKS,  STOCKBROKERS,  SAVINGS AND LOAN
ASSOCIATIONS   AND  CREDIT  UNIONS  WITH
MEMBERSHIP  IN  AN  APPROVED   SIGNATURE
GUARANTEE MEDALLION  PROGRAM),  PURSUANT
TO S.E.C. TITLE 17Ad-15.


                                      - 4 -




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