<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000810271
<NAME> Select Government Portfolio
<SERIES>
<NUMBER>012
<NAME>Smith Barney Investment Series
<S> <C>
<PERIOD-TYPE> Year
<FISCAL-YEAR-END> Oct-31-2001
<PERIOD-END> Oct-31-2000
<INVESTMENTS-AT-COST> 4,956,250
<INVESTMENTS-AT-VALUE> 5,053,450
<RECEIVABLES> 121,025
<ASSETS-OTHER> 0
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 5,174,475
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 178,815
<TOTAL-LIABILITIES> 178,815
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 4,688,931
<SHARES-COMMON-STOCK> 470,331
<SHARES-COMMON-PRIOR> 500,004
<ACCUMULATED-NII-CURRENT> 209,529
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 0
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 97,200
<NET-ASSETS> 4,995,660
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 303,545
<OTHER-INCOME> 0
<EXPENSES-NET> 40,959
<NET-INVESTMENT-INCOME> 262,586
<REALIZED-GAINS-CURRENT> 0
<APPREC-INCREASE-CURRENT> 57,700
<NET-CHANGE-FROM-OPS> 320,286
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 79,999
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 306,687
<NUMBER-OF-SHARES-REDEEMED> 344,523
<SHARES-REINVESTED> 8,163
<NET-CHANGE-IN-ASSETS> (70,767)
<ACCUMULATED-NII-PRIOR> 26,942
<ACCUMULATED-GAINS-PRIOR> 0
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 30,476
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 104,445
<AVERAGE-NET-ASSETS> 5,037,921
<PER-SHARE-NAV-BEGIN> 10.130
<PER-SHARE-NII> 0.530
<PER-SHARE-GAIN-APPREC> 0.120
<PER-SHARE-DIVIDEND> 0.160
<PER-SHARE-DISTRIBUTIONS> 0.000
<RETURNS-OF-CAPITAL> 0.000
<PER-SHARE-NAV-END> 10.620
<EXPENSE-RATIO> 0.80
</TABLE>
