<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000810271
<NAME> Select Growth & Income Portfolio
<SERIES>
<NUMBER>011
<NAME>Smith Barney Investment Series
<S> <C>
<PERIOD-TYPE> Year
<FISCAL-YEAR-END> Oct-31-2001
<PERIOD-END> Oct-31-2000
<INVESTMENTS-AT-COST> 17,837,086
<INVESTMENTS-AT-VALUE> 18,194,995
<RECEIVABLES> 136,489
<ASSETS-OTHER> 118
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 18,331,602
<PAYABLE-FOR-SECURITIES> 209,010
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 33,735
<TOTAL-LIABILITIES> 242,745
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 17,736,303
<SHARES-COMMON-STOCK> 1,678,885
<SHARES-COMMON-PRIOR> 301,491
<ACCUMULATED-NII-CURRENT> 86,795
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (92,150)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 357,909
<NET-ASSETS> 18,088,857
<DIVIDEND-INCOME> 54,417
<INTEREST-INCOME> 93,082
<OTHER-INCOME> 0
<EXPENSES-NET> 56,187
<NET-INVESTMENT-INCOME> 91,312
<REALIZED-GAINS-CURRENT> (90,237)
<APPREC-INCREASE-CURRENT> 328,473
<NET-CHANGE-FROM-OPS> 329,548
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 7,000
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 1,691,973
<NUMBER-OF-SHARES-REDEEMED> 315,226
<SHARES-REINVESTED> 647
<NET-CHANGE-IN-ASSETS> 15,043,481
<ACCUMULATED-NII-PRIOR> 2,483
<ACCUMULATED-GAINS-PRIOR> (1,913)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 44,203
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 121,406
<AVERAGE-NET-ASSETS> 5,901,906
<PER-SHARE-NAV-BEGIN> 10.100
<PER-SHARE-NII> 0.160
<PER-SHARE-GAIN-APPREC> 0.530
<PER-SHARE-DIVIDEND> 0.020
<PER-SHARE-DISTRIBUTIONS> 0.000
<RETURNS-OF-CAPITAL> 0.000
<PER-SHARE-NAV-END> 10.770
<EXPENSE-RATIO> 0.95
</TABLE>
