OPPENHEIMER GLOBAL BIO TECH FUND
497, 1994-08-19
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                  OPPENHEIMER GLOBAL BIO-TECH FUND
                  Supplement dated August 19, 1994
  to the Statement of Additional Information dated February 1, 1994

The Statement of Additional Information is amended as follows:

     1.    The paragraph entitled "Sandra Panem, Vice President and Portfolio
     Manager" under the caption "Trustees and Officers" on page 15 is 
     hereby deleted and replaced with the following:

           JAMES AYER, Vice President and Portfolio Manager
                Assistant Vice President of the Manager; an officer
                and portfolio manager of other OppenheimerFunds;
                formerly an International Equities Investment Officer
                with Brown Brothers Harriman & Company.




August 19, 1994                                               SAI750








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