MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1996-06-07
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<PAGE>
- --------------------------------------------------
OFFICERS AND DIRECTORS
 
Barton M. Biggs             James W. Grisham
  CHAIRMAN OF THE BOARD     VICE PRESIDENT
Frederick B. Whittemore     Michael F. Klein
  VICE-CHAIRMAN OF THE      VICE PRESIDENT
BOARD                       Harold J. Schaaff, Jr.
Warren J. Olsen             VICE PRESIDENT
  PRESIDENT AND DIRECTOR    Joseph P. Stadler
John D. Barrett II          VICE PRESIDENT
  DIRECTOR                  Valerie Y. Lewis
Gerard E. Jones             SECRETARY
  DIRECTOR                  Karl O. Hartmann
Andrew McNally, IV          ASSISTANT SECRETARY
  DIRECTOR                  James R. Rooney
Samuel T. Reeves            TREASURER
  DIRECTOR                  Joanna M. Haigney
Fergus Reid                 ASSISTANT TREASURER
  DIRECTOR
Frederick O. Robertshaw
  DIRECTOR
 
- --------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
CUSTODIANS
The Chase Manhattan Bank, N.A.
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- --------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- --------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- --------------------------------------------------
For current performance, current net asset value, or for assistance with your
account, please contact the Fund at (800) 548-7786. This report is authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                              HIGH YIELD PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1996
<PAGE>
LETTER TO SHAREHOLDERS
- --------
 
The  High  Yield Portfolio  seeks to  maximize  total return  by investing  in a
diversified portfolio of fixed income securities that offer a higher yield  than
that offered by debt securities in the three highest rating categories.
 
For  the three  month period  ended March  31, 1996,  the Portfolio  had a total
return of 3.15%  for the Class  A shares and  2.66% for the  Class B shares,  as
compared  to a total return  of 2.16% for the CS  First Boston High Yield Index.
The average annual total return for the  twelve months ended March 31, 1996  and
for  the period from inception on September  28, 1992 through March 31, 1996 was
19.89% and 12.34%, respectively, for the  Class A shares, as compared to  14.53%
and 10.84%, respectively, for the Index. As of March 31, 1996, the Portfolio had
an  SEC 30-day yield of 9.87%  for the Class A shares  and 9.67% for the Class B
shares.
 
The high yield market  performed well in  the face of a  sharp rise in  Treasury
yields   during  the  first  quarter  of  1996.  Once  again,  this  performance
demonstrates the high yield market's resiliency  and that it does not  correlate
well   with  general  interest  rate  movements.   The  latter  points  out  the
diversification benefits and value-added  that high yield  bonds can provide  an
investor.
 
PERFORMANCE COMPARED TO THE CS FIRST BOSTON HIGH YIELD INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                                 TOTAL RETURNS(2)
                                     -----------------------------------------
                                                     ONE      AVERAGE ANNUAL
                                         YTD        YEAR      SINCE INCEPTION
                                        -----     ---------  -----------------
<S>                                  <C>          <C>        <C>
PORTFOLIO--CLASS A.................        3.15%      19.89%         12.34%
PORTFOLIO--CLASS B(3)..............        2.66         N/A            N/A
INDEX..............................        2.16       14.53          10.84
</TABLE>
 
1.  The  CS First Boston  High Yield Index  is an unmanaged  index of high yield
    corporate bonds.
 
2.  Total returns for the Portfolio  reflect expenses waived and reimbursed,  if
    applicable,  by the  Adviser. Without  such waiver  and reimbursement, total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
- ------------------------------
THE PERFORMANCE RESULTS PROVIDED ARE FOR INFORMATIONAL PURPOSES ONLY AND  SHOULD
NOT  BE CONSTRUED  AS A  GUARANTEE OF  THE PORTFOLIO'S  FUTURE PERFORMANCE. PAST
PERFORMANCE SHOWN IS NOT PREDICTIVE OF FUTURE PERFORMANCE. INVESTMENT RETURN AND
PRINCIPAL VALUE WILL FLUCTUATE SO THAT AN INVESTOR'S SHARES, WHEN REDEEMED,  MAY
BE  WORTH MORE OR LESS THAN THEIR ORIGINAL COST. YIELDS WILL FLUCTUATE AS MARKET
CONDITIONS CHANGE.
 
While the  quarter was  good for  high yield,  some pressure  became evident  by
mid-March. Mutual fund inflows began to slow a bit yet new issuance continued at
a  strong pace. Spreads  had narrowed considerably  through February as ten-year
Treasury bonds had already risen fifty  basis points since the beginning of  the
year,  on their way to a seventy basis point widening by the end of the quarter.
This rate rise finally caused a negative return for the month of March but still
less than the loss  incurred by the  Treasury market. At the  end of March,  the
spread of the First Boston High Yield index was 418 basis points over Treasuries
versus a spread of 484 basis points at the beginning of the year.
 
Lower  rated  credits, traditionally  less interest  rate sensitive  than better
quality bonds, did best in this environment.  The spread between BB and B  rated
bonds narrowed at least twenty basis points. Even lower rated bonds tightened to
a greater extent. Gaming continued to be a strong sector.
 
Earnings momentum in the casinos is good and enabled Donald Trump to consolidate
and refinance two of his Atlantic City properties.
 
The  restaurant  sector also  performed well.  A  few distressed  issues rallied
sharply and others held their price while accruing interest at very high levels.
Underperformers tended to be longer duration, better quality bonds. Fitting into
this category were airlines, utilities and media bonds.
 
Looking forward, we see value in some of the cyclical issues in the marketplace.
Issuers in the steel, paper and auto sectors represent intriguing opportunities.
While the earnings outlook in these sectors is either poor or at best uncertain,
bond prices reflect  much if  not more than  the anticipated  problems. We  also
continue  to  like the  cable and  communications sectors  and will  maintain an
exposure to emerging markets.
 
Robert Angevine
PORTFOLIO MANAGER
 
April 1996
 
                                       2
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1996
<TABLE>
<CAPTION>
    FACE
   AMOUNT                                                    VALUE
    (000)                                                    (000)
- -------------                                              ---------
<C>             <S>                                        <C>
CORPORATE BONDS AND NOTES (85.1%)
  BANKING (1.2%)
$         775    United Savings Texas, 8.55%, 5/15/98      $    776
                                                           ---------
  BROADCAST-RADIO & TELEVISION (16.4%)
        1,000    Ackerley Communications, Inc., Series
                  A, 10.75%, 10/01/03                         1,060
        1,000    Cablevision Systems Corp., 10.75%,
                  4/01/04                                     1,044
        1,250    Continental Cablevision, Inc., 9.50%,
                  8/01/13                                     1,394
          400    Heritage Media, 11.00%, 10/01/02               428
        1,590    Lenfest Communications, 8.375%,
                  11/01/05                                    1,534
        2,400    Marcus Cable Co., (Step Bond), 0.00%,
                  12/15/05                                    1,524
          950    MFS Communications Co., Inc. (Step
                  Bond), 0.00%, 1/15/06                         594
        1,350    New World Communications Group Holding
                  Corp., Zero Coupon, Series B, 6/15/99         977
          900    Rogers Cablesystems Ltd., 11.00%,
                  12/01/15                                      967
        1,500    Viacom Inc., 8.00%, 7/07/06                  1,421
                                                           ---------
                                                             10,943
                                                           ---------
  BUILDING MATERIALS & COMPONENTS (0.9%)
          550    APS, Inc., 11.875%, 1/15/06                    565
                                                           ---------
  CHEMICALS (2.9%)
          750    Harris Chemical, 10.25%, 7/15/01               739
        1,000    Plastic Specialties & Technologies,
                  Inc., 11.25%, 12/01/03                        930
          250    Sherritt, Inc., 10.50%, 3/31/14                275
                                                           ---------
                                                              1,944
                                                           ---------
  CONSTRUCTION (1.0%)
        1,160    Echostar Satellite Broadcast, (Step
                  Bond), 0.00%, 3/15/04                         699
                                                           ---------
  ENTERTAINMENT & LEISURE (4.2%)
          886    Kloster Cruise Ltd., 13.00%, 5/01/03           678
        2,000    Six Flags Theme Park, Inc., (Step
                  Bond), 12.25%, 6/15/05                      1,640
 
<CAPTION>
    FACE
   AMOUNT                                                    VALUE
    (000)                                                    (000)
- -------------                                              ---------
<C>             <S>                                        <C>
$         500    Stena AB, 10.50%, 12/15/05                $    505
                                                           ---------
                                                              2,823
                                                           ---------
  ENVIRONMENTAL CONTROLS (1.9%)
        1,200    Norcal Waste Systems, 12.50%, 11/15/05       1,239
                                                           ---------
  FINANCIAL SERVICES (6.5%)
          925    APP International Finance, 11.75%,
                  10/01/05                                      911
          550    GPA Investments, 6.40%, 11/19/98               510
          940    Reliance Group Holdings Inc., 9.00%,
                  11/15/00                                      954
        1,000    Terra Nova Holdings, 10.75%, 7/01/05         1,110
        1,189    Tiphook Finance Corp., 8.00%, 3/15/00          877
                                                           ---------
                                                              4,362
                                                           ---------
  FOOD (3.1%)
        1,150    Pilgrim's Pride Corp., 10.875%, 8/01/03      1,090
          975    RJR Nabisco, Inc., 8.75%, 8/15/05              951
                                                           ---------
                                                              2,041
                                                           ---------
  FOOD SERVICE & LODGING (1.5%)
          435    La Quinta Inns, Inc., 9.25%, 5/15/03           463
          500    United Meridian Corp., 10.375%,
                  10/15/05                                      525
                                                           ---------
                                                                988
                                                           ---------
  GAMING & LODGING (1.5%)
          500    Casino America, 11.50%, 11/15/01               500
          522    Louisiana Casino Cruises, 11.50%,
                  12/01/98                                      502
                                                           ---------
                                                              1,002
                                                           ---------
  HEALTH CARE SUPPLIES & SERVICES (0.8%)
          500    Tenet Healthcare Corp., 10.125%,
                  3/01/05                                       538
                                                           ---------
  MACHINERY (1.2%)
          745    SD Warren Co., 12.00%, 12/15/04                788
                                                           ---------
  MATERIALS (3.2%)
          500    IMC Fertilizer, 9.25%, 10/01/00                530
        1,500    IMC Fertilizer, 9.45%, 12/15/11              1,641
                                                           ---------
                                                              2,171
                                                           ---------
  METALS (2.8%)
          750    Algoma Steel, Inc., (Yankee Bond),
                  12.375%, 7/15/05                              738
</TABLE>
 
                                       3
<PAGE>
<TABLE>
<CAPTION>
    FACE
   AMOUNT                                                    VALUE
    (000)                                                    (000)
- -------------                                              ---------
<C>             <S>                                        <C>
  METALS (CONTINUED)
$         525    Jet Equipment Trust, Series 95-D,
                  11.44%, 11/01/14                         $    577
          650    Sheffield Steel Corp., 12.00%, 11/01/01        580
                                                           ---------
                                                              1,895
                                                           ---------
  MISCELLANEOUS MATERIALS & COMMODITIES (0.6%)
          420    Beverly Enterprises, Inc., 9.00%,
                  2/15/06                                       404
                                                           ---------
  MULTI-INDUSTRY (4.1%)
          695    AMF Group, Inc., (Step Bond), 0.00%,
                  3/15/06                                       381
          250    Howmet Corp., 10.00%, 12/01/03                 263
          350    Riverwood International, 10.25%,
                  4/01/06                                       351
          565    TLC Beatrice International Holdings,
                  11.50%, 10/01/05                              573
        1,195    Unisys Corp., 12.00%, 4/15/03                1,189
                                                           ---------
                                                              2,757
                                                           ---------
  PACKAGING & CONTAINER (4.6%)
          500    Owens-Illinois, Inc., 10.50%, 6/15/02          522
        1,500    Owens-Illinois, Inc., 9.95%, 10/15/04        1,553
        1,000    Stone Container Corp., 10.75%, 10/01/02      1,000
                                                           ---------
                                                              3,075
                                                           ---------
  PUBLISHING (1.5%)
          690    Crown Paper Co., 11.00%, 9/01/05               638
          500    Marvel Parent Holdings, Zero Coupon,
                  4/15/98                                       373
                                                           ---------
                                                              1,011
                                                           ---------
  REAL ESTATE (0.7%)
          500    HMC Acquisition Properties, 9.00%,
                  12/15/07                                      477
                                                           ---------
  RETAIL -- GENERAL (3.9%)
          800    Host Marriot Travel Plaza, Series B,
                  9.50%, 5/15/05                                776
          840    Revlon Worldwide, Series B, Zero
                  Coupon, 3/15/98                               660
        1,500    Southland Corp., 5.00%, 12/15/03             1,208
                                                           ---------
                                                              2,644
                                                           ---------
  TELECOMMUNICATIONS (9.4%)
        3,000    Dial Call Communications, (Step Bond),
                  0.00%, 4/15/04                              1,890
        2,250    Nextel Communications, (Step Bond),
                  0.00%, 8/15/04                              1,316
          400    Paging Network, 10.125%, 8/01/07               422
          500    Rogers Communications, Inc., 10.875%,
                  4/15/04                                       520
<CAPTION>
    FACE
   AMOUNT                                                    VALUE
    (000)                                                    (000)
- -------------                                              ---------
<C>             <S>                                        <C>
 
$       1,500    Telefonica de Argentina, (Yankee Bond),
                  11.875%, 11/01/04                        $  1,568
          940    Telewest PLC, (Step Bond), 0.00%,
                  10/01/07                                      569
                                                           ---------
                                                              6,285
                                                           ---------
  TEXTILES & APPAREL (3.1%)
        1,000    Polysindo Eka Perkasa, (Yankee Bond),
                  13.00%, 6/15/01                             1,055
        1,000    Westpoint Stevens, Inc., 9.375%,
                  12/15/05                                      995
                                                           ---------
                                                              2,050
                                                           ---------
  TRANSPORTATION (2.1%)
          204    America West Airlines, 6.00%, 3/31/97          191
        1,500    Venture Holdings, 9.75%, 4/01/04             1,200
                                                           ---------
                                                              1,391
                                                           ---------
  UTILITIES (6.0%)
        1,478    Beaver Valley Funding Corp., (Lease
                  Obligation Bond), 9.00%, 6/01/17            1,245
        1,250    California Energy Co., Inc., 9.875%,
                  6/30/03                                     1,281
        1,400    First PV Funding Corp., (Lease
                  Obligation Bond), Series 1986B,
                  10.15%, 1/15/16                             1,460
                                                           ---------
                                                              3,986
                                                           ---------
TOTAL CORPORATE BONDS AND NOTES (Cost $56,005)               56,854
                                                           ---------
ASSET BACKED SECURITIES (1.7%)
  AEROSPACE & DEFENSE (0.5%)
          365    Airplanes Pass Through Trust, Series 1,
                  Class D, 10.875%, 3/15/19                     372
                                                           ---------
  BANKING (0.4%)
          349    PNC Mortgage Securities Corp., Series
                  1995-2, Class B4, REMIC, 7.50%,
                  9/25/25                                       273
                                                           ---------
  FINANCIAL SERVICES (0.8%)
          311    GE Capital Mortgage Services Inc.,
                  Series 1995-12, Class B3, REMIC,
                  7.91%, 8/25/25                                244
          350    Prudential Home Mortgage Securities,
                  Series 1996-4, Class B3, REMIC, 6.50%,
                  4/25/26                                       262
                                                           ---------
                                                                506
                                                           ---------
TOTAL ASSET BACKED SECURITIES (Cost $1,172)                   1,151
                                                           ---------
</TABLE>
 
                                       4
<PAGE>
<TABLE>
<CAPTION>
    FACE
   AMOUNT                                                    VALUE
    (000)                                                    (000)
- -------------                                              ---------
<C>             <S>                                        <C>
FOREIGN GOVERNMENT BONDS (5.3%)
  BONDS (5.3%)
$       3,710    Federative Republic of Brazil, Par
                  Bond, Series Z-L, (Step Bond), 4.25%,
                  4/15/24                                  $  1,887
        1,500    Republic of Argentina, Series L,
                  "Euro" (Floating Rate), 6.313%,
                  3/31/05                                     1,082
        1,145    Republic of Argentina, Series L, "Euro"
                  (Floating Rate), 5.25%, 3/31/23               595
                                                           ---------
TOTAL FOREIGN GOVERNMENT BONDS (Cost $3,323)                  3,564
                                                           ---------
<CAPTION>
       SHARES
- -------------
<C>             <S>                                        <C>
COMMON STOCKS (0.8%)
  BUILDING MATERIALS & COMPONENTS (0.6%)
       30,331    Walter Industries, Inc.                        417
                                                           ---------
  FINANCIAL SERVICES (0.0%)
        1,268    WestFed Holdings, Inc., Class B                 --
                                                           ---------
  FOOD SERVICE & LODGING (0.2%)
        1,300    Motels of America, Inc.                         98
                                                           ---------
  GAMING & LODGING (0.0%)
          500    Trump Taj Mahal, Class A                        13
                                                           ---------
TOTAL COMMON STOCKS (Cost $600)                                 528
                                                           ---------
PREFERRED STOCKS (0.0%)
  FINANCIAL SERVICES (0.0%)
        3,239    WestFed Holdings, Inc., Series A (Cost
                  $56)                                           --
                                                           ---------
<CAPTION>
   NO. OF
   RIGHTS
- -------------
<C>             <S>                                        <C>
RIGHTS (0.0%)
  BROADCAST-RADIO & TELEVISION (0.0%)
       35,000    SpectraVision, Inc., expiring 10/08/97
                  (Cost $133)                                     2
                                                           ---------
<CAPTION>
   NO. OF
  WARRANTS
- -------------
<C>             <S>                                        <C>
WARRANTS (0.8%)
  AEROSPACE & DEFENSE (0.0%)
          500    Sabreliner Corp., expiring 4/15/03               2
                                                           ---------
  ELECTRICAL EQUIPMENT (0.6%)
       28,000    Protection One Alarm, Inc., expiring
                  4/03/03                                       402
                                                           ---------
  GAMING & LODGING (0.0%)
        2,700    Casino Magic Corp., expiring 10/14/96           --
<CAPTION>
   NO. OF                                                    VALUE
  WARRANTS                                                   (000)
- -------------                                              ---------
<C>             <S>                                        <C>
        1,725    Louisiana Casino Cruises, expiring
                  12/01/98                                 $     17
                                                           ---------
                                                                 17
                                                           ---------
  INSURANCE (0.0%)
          500    Horace Mann Educators Corp., expiring
                  4/3/99                                          7
                                                           ---------
  METALS (0.1%)
        8,250    Sheffield Steel Corp., expiring
                  11/01/01                                       25
                                                           ---------
  PACKAGING & CONTAINER (0.0%)
        1,000    Crown Packaging Holdings, expiring
                  11/01/03                                        8
                                                           ---------
  REAL ESTATE (0.1%)
        1,000    Petro PSC Properties L.P., expiring
                  6/01/97                                        33
                                                           ---------
  TELECOMMUNICATIONS (0.0%)
        3,000    Dial Page, Inc., expiring 4/25/99               --
                                                           ---------
TOTAL WARRANTS (Cost $228)                                      494
                                                           ---------
<CAPTION>
   NO. OF
    UNITS
- -------------
<C>             <S>                                        <C>
UNITS (2.1%)
  BROADCAST-RADIO & TELEVISION (0.1%)
        1,250    American Telecasting, (Step Bond),
                  14.50%, 8/15/05                                42
                                                           ---------
  GAMING & LODGING (0.7%)
    2,207,906    Maritime Group, Series A, 13.50%,
                  2/15/97                                       487
                                                           ---------
  METALS (1.3%)
        1,000    Sheffield Steel Corp. (1st Mortgage
                  bond + 5 Common Stock Warrants),
                  12.00%, 11/01/01                              895
                                                           ---------
TOTAL UNITS (Cost $3,453)                                     1,424
                                                           ---------
<CAPTION>
    FACE
   AMOUNT
    (000)
- -------------
<C>             <S>                                        <C>
SHORT-TERM INVESTMENT (0.9%)
  REPURCHASE AGREEMENT (0.9%)
$         624    The Chase Manhattan Bank, N.A., 5.15%,
                  dated 3/29/96, due 4/01/96, to be
                  repurchased at $624, collateralized by
                  $624 United States Treasury Bonds,
                  11.25%, due 02/15/15, valued at $639
                  (Cost $624)                                   624
                                                           ---------
TOTAL INVESTMENTS (96.7%) (Cost $65,594)                     64,641
                                                           ---------
</TABLE>
 
                                       5
<PAGE>
<TABLE>
<CAPTION>
                                                            AMOUNT
                                                             (000)
                                                           ---------
<C>             <S>                                        <C>
OTHER ASSETS AND LIABILITIES (3.3%)
 Other Assets                                              $  2,663
 Liabilities                                                   (472)
                                                           ---------
                                                              2,191
                                                           ---------
NET ASSETS (100%)                                          $ 66,832
                                                           ---------
                                                           ---------
CLASS A SHARES:
  Net Assets                                               $ 65,437
  Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                             6,175
  Net Asset Value, Offering and Redemption Price
   Per Share                                               $  10.60
                                                           ---------
                                                           ---------
CLASS B SHARES:
  Net Assets                                               $  1,395
  Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                               132
  Net Asset Value, Offering and Redemption Price
   Per Share                                               $  10.58
                                                           ---------
                                                           ---------
</TABLE>
 
- ----------------------------------
REMIC -- Real Estate Mortgage Investment Conduit
Step bond-coupon rate increases in increments to maturity. Rate disclosed is as
of March 31, 1996. Maturity date disclosed is the ultimate maturity date.
 
                                       6


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