MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1996-06-07
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<PAGE>
- --------------------------------------------------
OFFICERS AND DIRECTORS
 
Barton M. Biggs             James W. Grisham
  CHAIRMAN OF THE BOARD     VICE PRESIDENT
Frederick B. Whittemore     Michael F. Klein
  VICE-CHAIRMAN OF THE      VICE PRESIDENT
BOARD                       Harold J. Schaaff, Jr.
Warren J. Olsen             VICE PRESIDENT
  PRESIDENT AND DIRECTOR    Joseph P. Stadler
John D. Barrett II          VICE PRESIDENT
  DIRECTOR                  Valerie Y. Lewis
Gerard E. Jones             SECRETARY
  DIRECTOR                  Karl O. Hartmann
Andrew McNally, IV          ASSISTANT SECRETARY
  DIRECTOR                  James R. Rooney
Samuel T. Reeves            TREASURER
  DIRECTOR                  Joanna M. Haigney
Fergus Reid                 ASSISTANT TREASURER
  DIRECTOR
Frederick O. Robertshaw
  DIRECTOR
 
- --------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- ---------------------------------------------
CUSTODIANS
The Chase Manhattan Bank, N.A.
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- --------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- --------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- ---------------------------------------------
For current performance, current net asset value, or for assistance with your
account, please contact the Fund at (800) 548-7786. This report is authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                        EMERGING MARKETS DEBT PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1996
<PAGE>
LETTER TO SHAREHOLDERS
- -------
 
The  investment objective of  the Emerging Markets Debt  Portfolio is high total
return  through  investment   primarily  in  debt   securities  of   government,
government-related and corporate issuers located in emerging countries.
 
For  the three  month period  ended March  31, 1996,  the Portfolio  had a total
return of 5.01%  for the Class  A shares and  3.92% for the  Class B shares,  as
compared  to a total return  of 3.76% for the  J.P. Morgan Emerging Markets Bond
Index. The average  annual total return  for the twelve  months ended March  31,
1996  and for the  period from inception  on February 1,  1994 through March 31,
1996 was 57.20% and 6.96%, respectively, for the Class A shares, as compared  to
48.81%  and  3.44%, respectively,  for  the Index.  As  of March  31,  1996, the
Portfolio had an SEC 30-day  yield of 14.80% for the  Class A shares and  14.48%
for the Class B shares.
 
PERFORMANCE COMPARED TO THE J.P. MORGAN EMERGING MARKETS BOND INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                               TOTAL RETURNS(2)
                                    ---------------------------------------
                                                  ONE      AVERAGE ANNUAL
                                       YTD       YEAR      SINCE INCEPTION
                                    ---------  ---------  -----------------
<S>                                 <C>        <C>        <C>
PORTFOLIO--CLASS A................       5.01%     57.20%          6.96%
PORTFOLIO--CLASS B(3).............       3.92        N/A            N/A
INDEX.............................       3.76      48.81           3.44
</TABLE>
 
1.  The  J.P.  Morgan Emerging  Markets Bond  Index is  a market  weighted index
    composed of  all Brady  bonds outstanding  and includes  Argentina,  Brazil,
    Bulgaria, Mexico, Nigeria, the Philippines, Poland and Venezuela.
 
2.  Total  returns for the Portfolio reflect  expenses waived and reimbursed, if
    applicable, by the  Adviser. Without  such waiver  and reimbursement,  total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
 
- ------------------------------
THE PERFORMANCE RESULTS PROVIDED IN THIS OVERVIEW ARE FOR INFORMATIONAL PURPOSES
ONLY  AND  SHOULD NOT  BE CONSTRUED  AS  A GUARANTEE  OF THE  PORTFOLIO'S FUTURE
PERFORMANCE. PAST PERFORMANCE  SHOWN IS  NOT PREDICTIVE  OF FUTURE  PERFORMANCE.
INVESTMENT  RETURN  AND PRINCIPAL  VALUE WILL  FLUCTUATE  SO THAT  AN INVESTOR'S
SHARES, WHEN  REDEEMED, MAY  BE WORTH  MORE OR  LESS THAN  THEIR ORIGINAL  COST.
PLEASE  SEE  THE PROSPECTUS  FOR A  DESCRIPTION  OF CERTAIN  RISK CONSIDERATIONS
ASSOCIATED  WITH  INTERNATIONAL  INVESTING.  YIELDS  WILL  FLUCTUATE  AS  MARKET
CONDITIONS CHANGE.
 
The  positive momentum  that emerging  markets debt  witnessed in  the first few
weeks of the year faded as the U.S. bond markets re-evaluated the likely  future
direction of U.S. interest rates. The U.S. yield curve at that point of time was
discounting  continued easing  of monetary policy,  given the weak  state of the
economy. The inventory adjustment combined with a restrictive fiscal stance  and
weak  conditions  in the  external sector  had produced  sub-par growth  for the
fourth quarter  of 1995.  The continuation  of these  conditions into  1996  was
questioned  by  bond  market  participants  at the  beginning  of  the  year and
leveraged investors  unwound  positions in  the  short  end of  the  market  and
initiated  the reversal in yields.  This back-up in yields  was exacerbated by a
spate of economic releases which suggested that the economy was in fact  picking
up  steam in  the first quarter.  Rates eventually  increased by 120  bps in the
short end and 80 bps at the long end of the yield curve.
 
The reversal in the fortunes  of the U.S. bond market  had an adverse impact  on
emerging  market  debt  asset  prices.  Deleveraging  and  a  reduction  in risk
exposures to the asset class prompted a  10% correction in prices over a  course
of  four weeks. Fixed rate collateralized bonds, bonds with the highest interest
rate duration,  were the  hardest  hit. Floating-rate  non-collateralized  bonds
outperformed due to their low interest rate durations.
 
The Portfolio outperformed over the quarter as it was defensively positioned for
the  move in interest  rates, overweight positions in  money market and floating
rate assets with low durations and a sizable cash position during the correction
in  the  market.  Our  country  allocations  also  were  defensive  in   nature;
underweight  in Argentina,  Mexico and Brazil,  the countries  whose assets were
most likely  to  be  negatively  affected  by  overall  market  conditions,  and
overweight  in Russia, Morocco, Venezuela and  Panama, countries with lower than
average market exposure.
 
Over the  quarter, Bulgaria,  Argentina, Mexico  and Russia  underperformed  the
overall  index and Peru, Panama, Poland,  Venezuela and Ecuador outperformed the
market on  average. Poland  received an  investment grade  rating from  S&P  and
became  the first emerging country to migrate from the asset class. Polish Brady
bonds rallied  strongly on  the  news as  rating  action recognized  the  strong
performance of the economy and the implementation of structural reforms over the
last  four  years. Panama  and Peru  outperformed as  they continued  with their
steady economic performance and underweight investors
 
                                       2
<PAGE>
sought to  increase their  exposures  to these  countries. Some  questions  were
raised  about the  sustainability of growth  in Peru, given  the continuation of
large current account deficits  and a strong exchange  rate. Remedial action  in
the  form of  a tightening  of monetary policy  to cool  aggregate demand should
alleviate these concerns. We had retained our overweight positions in Panama for
most of the quarter and had reduced  some of our exposure into market  strength.
We remain positive on the credit and will seek to maintain our current exposure.
 
Venezuela  continued to  make slow and  steady progress  towards implementing an
orthodox  stabilization  program.  Progress  was  not  without  hiccups  as  the
political leadership postponed making harsh economic decisions, until there were
really  no alternatives left  to rescue the economy  from an implosion resulting
from a  severe decline  in confidence.  The  eventual program  had most  of  the
elements of an orthodox stabilization program. Venezuelan bonds rallied into the
news  of the impending program as default risk was sharply reduced. We increased
our exposure to Venezuela during a bout of market skepticism and will retain our
aggressive overweight  position  to capture  high  yields and  possible  further
tightening of credit spreads.
 
Argentina  underperformed  during  the  first quarter  by  500  basis  points as
continued weakness in  the economy,  resulting from the  tequila affect  induced
1995  recession,  produced  another  round of  political  wrangling  between the
President and his Finance  Minister over policy  alternatives available to  jump
start  growth  in  1996.  Economic  growth  should  gather  steam  as  the  year
progresses, as firms rebuild inventories  and consumer expenditures pick up.  We
reduced our exposure to Argentina in the middle of the quarter as we became more
defensive on the market and increased it again towards the end of the quarter as
political problems appeared to have been sorted out.
 
Mexican  Brady bonds  underperformed the market  as it was  affected by concerns
over the impact of higher interest  rates on the domestic economy. Our  exposure
is  limited  primarily  to  local  currency  denominated  treasury  bills, which
performed well as the currency strengthened in nominal terms and interest  rates
came down from the lofty levels seen at the beginning of the year. Mexican Brady
bonds  trade at relatively tight spreads compared  to the rest of the market and
we do  not believe  they offer  value at  such levels.  The export-led  economic
recovery  seems to be taking a firmer  hold and a drastic reduction in inflation
towards to the second half of the year should result in a virtuous cycle of  low
inflation,  low interest rates and higher  growth. The economy, however, remains
vulnerable to external  shocks and  the recent  appreciation of  the peso  could
portend  trouble ahead. We  remain cautious on Mexico  and believe higher yields
elsewhere in the market are more attractive.
 
Brazil continues  to be  the solid  performer of  the market.  A strong  vibrant
private  sector, reasonable economic  growth, lower inflation,  and high foreign
reserves make it a  safer place to invest  in the long term.  In the short  run,
however,  momentum  to  implement  reforms that  would  increase  the  long term
viability of the Real plan, such as  the measures to reform social security  and
the  administrative machinery of the state, appears  to be getting caught in the
politics as usual pre-election atmosphere of the Brazilian congress. Significant
progress on these issues is necessary to contain the fiscal deficit and maintain
economic stability. Brazil will remain a  core holding in our portfolio, but  we
will  not overweight Brazil in the absence  of any real chance of the leadership
regaining the  upper  hand in  its  attempt  to push  through  necessary  reform
measures in 1996.
 
Russia remains one of our largest positions. Russian loans underperformed in the
first  quarter as concerns over a possible Communist victory in the Presidential
elections depressed prices. We  believe that the  incumbent President will  gain
ground  as the  election date  approaches and  prices should  rally in  the next
quarter. Current valuations suggest that  Russian non-performing loans trade  at
wider  spreads than Bulgaria. Based on  credit fundamentals fair value should be
at least 500 basis points tighter than current levels.
 
We remain cautiously  optimistic on  emerging markets debt.  Despite a  negative
U.S.  rate environment in  the first quarter, emerging  debt has performed well.
This has been true because of a contraction of credit spreads based on improving
economic stories.  Management of  portfolio  duration remains  a key  aspect  of
performance.  Credit spreads  are likely to  be volatile in  an environment when
interest rates are likely to go up. Our exposure to money market instruments  in
local currencies should provide us with some diversification benefits.
 
Paul Ghaffari
PORTFOLIO MANAGER
 
April 1996
 
                                       3
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1996
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
DEBT INSTRUMENTS (88.6%)
  ARGENTINA (12.4%)
    BONDS (12.4%)
 $        2,000    Republic of Argentina BOCON,
                    Series M1, (Floating Rate),
                    3.565% 4/01/07                      $   1,385
          9,000    Republic of Argentina BOCON,
                    Series 1 DL, (Floating Rate),
                    3.188%, 4/01/01                         8,415
 ARP      3,000    Republic of Argentina BOCON,
                    Series 2, (Floating Rate), 3.565%
                    9/01/02                                 2,003
 $        6,000    Republic of Argentina Discount
                    Bonds, (Floating Rate), 6.563%,
                    3/31/23                                 3,859
          7,673    Republic of Argentina, Series L,
                    "Euro", (Floating Rate), 6.813%,
                    3/31/05                                 5,534
                                                        ---------
                                                           21,196
                                                        ---------
  BRAZIL (18.1%)
    BONDS (18.1%)
         20,000    Federative Republic of Brazil Par
                    Bond, Series Z-L, (Floating
                    Rate), 6.813%, 4/15/24                 12,825
         14,000    Federative Republic of Brazil Par
                    Bond, Series Z-L, (Floating
                    Rate), 4.25%, 4/15/24                   7,123
         18,794    Federative Republic of Brazil,
                    Series C, "Euro", (Floating
                    Rate), PIK, 8.00%, 4/15/14             11,088
                                                        ---------
                                                           31,036
                                                        ---------
  BULGARIA (2.0%)
    BONDS (2.0%)
          5,000    Bulgaria Discount Bonds, Series A,
                    "Euro" (Floating Rate), 6.25%,
                    7/28/24                                 2,491
          2,000    Bulgaria Interest Arrears Bonds,
                    (Floating Rate), 6.25%, 7/28/11           884
                                                        ---------
                                                            3,375
                                                        ---------
  ECUADOR (1.7%)
    BONDS (1.7%)
          1,000    Republic of Ecuador Discount
                    Bonds, "Euro", (Floating Rate)
                    6.063%, 2/28/25                           541
            181    Republic of Ecuador Discount
                    Bonds, (Floating Rate) 6.063%,
                    2/28/25                                    98
 
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
 $        3,230    Republic of Ecuador IE Bonds,
                    (Floating Rate), 6.50%, 12/21/04    $   2,229
                                                        ---------
                                                            2,868
                                                        ---------
  MEXICO (4.7%)
    BONDS (4.7%)
  MXP    19,092    Banamex Pagare Discount Bond,
                    4/03/97                                 1,798
         32,143    Banamex Pagare Discount Bond,
                    10/09/97                                2,635
 $        1,000    Grupo Mexicano de Desarrollo,
                    8.25%, 2/17/01                            520
 MXP      8,000    National Financiera, 17.00%,
                    2/26/99                                 1,992
 $        1,500    Mexican Discount Bond, Series A,
                    (Floating Rate), 6.766%,
                    12/31/19, (Value Recovery Rights
                    Attached)                               1,133
                                                        ---------
                                                            8,078
                                                        ---------
  MOROCCO (2.8%)
    LOAN AGREEMENT (2.8%)
          7,000    Kingdom of Morocco Restructuring
                    and Consolidating Agreement,
                    Tranche A, (Floating Rate),
                    1/01/09 (Participation: Chase,
                    Morgan Guaranty Trust Co. of
                    N.Y.)                                   4,874
                                                        ---------
  NIGERIA (1.5%)
    BOND (1.5%)
          5,000    Nigeria Par Bonds, (Floating
                    Rate), 6.25%, 11/15/20, (Warrants
                    Attached)                               2,556
                                                        ---------
  PANAMA (5.0%)
    LOAN AGREEMENT (5.0%)
         10,113    Republic of Panama Loans                 8,596
                                                        ---------
  PERU (2.9%)
    BOND (2.9%)
          9,699    Peru Working Capital Lines,
                    12/29/49 (Floating Rate)                4,910
                                                        ---------
  POLAND (1.1%)
    NOTE (1.1%)
          2,224    Republic of Poland Note, Zero
                    Coupon, 1/08/97                         1,903
                                                        ---------
  RUSSIA (18.0%)
    LOAN AGREEMENTS (10.5%)
 CHF     12,800    Bank for Foreign Economic Affairs,
                    (Floating Rate)                         3,615
</TABLE>
 
                                       4
<PAGE>
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
  RUSSIA (CONTINUED)
  DEM    56,500    Bank for Foreign Economic Affairs,
                    (Floating Rate)                     $  14,396
                                                        ---------
                                                           18,011
                                                        ---------
    BONDS (7.5%)
 $        5,440    Ministry of Finance Tranche III,
                    3.00%, 5/14/99                          3,937
         21,450    Ministry of Finance Tranche IV,
                    3.00%, 5/14/03                          8,915
                                                        ---------
                                                           12,852
                                                        ---------
                                                           30,863
                                                        ---------
  SOUTH AFRICA (4.4%)
    BONDS (4.4%)
 ZAR      3,500    Republic of South Africa, Series
                    147, 11.50%, 5/30/00                      793
         18,340    Republic of South Africa, Series
                    153, 13.00%, 8/31/10                    4,020
          8,120    Republic of South Africa, Series
                    162, 12.50%, 1/15/02                    1,849
          2,800    Republic of South Africa, Series
                    175, 9.00%, 10/15/02                      529
          2,100    Republic of South Africa, Series
                    177, 9.50%, 5/15/07                       366
                                                        ---------
                                                            7,557
                                                        ---------
  VENEZUELA (14.0%)
    BONDS (14.0%)
 $       28,000    Republic of Venezuela Debt
                    Conversion Bonds, Series DL,
                    (Floating Rate), 6.563%, 12/18/07      16,975
         12,500    Republic of Venezuela Par Bond,
                    Series W-B, 6.75%, 3/31/20 (Oil
                    Warrants Attached)                      7,078
                                                        ---------
                                                           24,053
                                                        ---------
TOTAL DEBT INSTRUMENTS (Cost $152,806)                    151,865
                                                        ---------
SHORT-TERM INVESTMENTS (12.2%)
  MEXICO (6.5%)
    BILLS (6.5%)
  MXP    19,994    Mexican Cetes, Zero Coupon,
                    7/18/96                                 2,372
         41,820    Mexican Cetes, Zero Coupon,
                    8/08/96                                 4,862
         35,000    Mexican Cetes, Zero Coupon,
                    9/26/96                                 3,889
                                                        ---------
                                                           11,123
                                                        ---------
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
 
  TURKEY (3.3%)
    BILLS (3.3%)
TRL 298,720,000    Turkish T-Bill, Zero Coupon,
                    6/26/96                             $   3,395
    204,000,000    Turkish T-Bill, Zero Coupon,
                    7/10/96                                 2,240
                                                        ---------
                                                            5,635
                                                        ---------
  UNITED STATES (2.4%)
    REPURCHASE AGREEMENT (2.4%)
 $        4,058    The Chase Manhattan Bank, N.A.,
                    5.15%, dated 3/29/96, due
                    4/01/96, to be repurchased at
                    $4,060, collateralized by $4,115
                    United States Treasury Notes,
                    6.00%, due 8/31/97, valued at
                    $4,083 (Cost $4,058)                    4,058
                                                        ---------
TOTAL SHORT-TERM INVESTMENTS (Cost $23,904)                20,816
                                                        ---------
TOTAL INVESTMENTS (100.8%) (Cost $176,710)                172,681
                                                        ---------
OTHER ASSETS AND LIABILITIES (-0.8%)
 Other Assets                                              53,044
 Liabilities                                              (54,402)
                                                        ---------
                                                           (1,358)
                                                        ---------
NET ASSETS (100%)                                       $ 171,323
                                                        ---------
                                                        ---------
CLASS A SHARES:
 Net Assets                                              $169,452
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                          18,782
 Net Asset Value, Offering and Redemption Price
  Per Share                                                 $9.02
                                                        ---------
                                                        ---------
CLASS B SHARES:
 Net Assets                                                $1,871
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                             208
 Net Asset Value, Offering and Redemption Price
  Per Share                                                 $9.02
                                                        ---------
                                                        ---------
</TABLE>
 
- ----------------------------------
 
<TABLE>
<CAPTION>
<S>        <C>        <C>
ARP               --  Argentine Peso
CHF               --  Swiss Franc
DEM               --  Deutsche Mark
MXP               --  Mexican Peso
TRL               --  Turkish Lira
ZAR               --  South African Rand
PIK               --  Payment-In-Kind. Income may be paid in additional
                      securities or cash at the discretion of the issuer.
</TABLE>
 
                                       5


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