<PAGE>
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. )*
BIOTRANSPLANT INCORPORATED
-----------------------------------------------------------------
(Name of Issuer)
Common Stock $.01 par value
-----------------------------------------------------------------
(Title of Class of Securities)
09066Y107
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(CUSIP Number)
Check the following box if a fee is being paid with this statement
[X]. (A fee is not required only if the reporting person: (1) has
a previous statement on file reporting beneficial ownership of
more than five percent of the class of securities described in
Item 1; and (2) has filed no amendment subsequent thereto
reporting beneficial ownership of five percent or less of such
class.) (See Rule 13d-7.)
*The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect to
the subject class of securities, and for any subsequent amendment
containing information which would alter the disclosures provided
in a prior cover page.
The information required in the remainder of this cover page
shall not be deemed to be "filed" for the purpose of Section 18
of the Securities Exchange Act of 1934 ("Act") or otherwise
subject to the liabilities of that section of the Act but shall
be subject to all other provisions of the Act (however, see the
Notes).
(Continued on following page(s))
Page 1 of 17 pages
-- --
<PAGE>
CUSIP No. 09066Y107 13G Page 2 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Ventures II, L.P.
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2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 1,570,886
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
1,570,886
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,570,886
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
18.2%
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12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 3 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Partners II, L.P.
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 1,570,886
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
1,570,886
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,570,886
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
18.2%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 4 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Ventures III, L.P.
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2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 874,539
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
874,539
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
874,539
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.1%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 5 of 17 pages
------------ ----- -----
-------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Partners III, L.P.
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 874,539
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
874,539
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
874,539
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.1%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 6 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Ventures IV, L.P.
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 258,075
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
258,075
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
258,075
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
3.0%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 7 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
HealthCare Partners IV, L.P.
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 258,075
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
258,075
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
258,075
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
3.0%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 8 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
James H. Cavanaugh, Ph.D.
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2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
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3. SEC USE ONLY
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4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 2,703,500
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
2,703,500
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9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,703,500
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10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
30.9%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 9 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Harold R. Werner
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2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 2,703,500
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
2,703,500
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,703,500
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
30.9%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 10 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
William Crouse
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 2,703,500
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
2,703,500
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,703,500
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
30.9%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
CUSIP No. 09066Y107 13G Page 11 of 17 pages
------------ ----- -----
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1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
John W. Littlechild
-------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
-------------------------------------------------------------------
3. SEC USE ONLY
-------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
-------------------------------------------------------------------
5. SOLE VOTING POWER
-----------------------------------------------
NUMBER OF 6. SHARED VOTING POWER
SHARES
BENEFICIALLY 2,703,500
OWNED BY -----------------------------------------------
EACH 7. SOLE DISPOSITIVE POWER
REPORTING
PERSON
WITH -----------------------------------------------
8. SHARED DISPOSITIVE POWER
2,703,500
-------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
2,703,500
-------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES* [ ]
-------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
30.9%
-------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
-------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
Page 12 of 17 Pages
Item 1.
(a) Name of Issuer:
BioTransplant Incorporated
(b) Address of Issuer's Principal Executive Offices:
Charlestown Navy Yard, Building 75, Third Avenue
Charlestown, Massachusetts 02129
Item 2.
(a) Name of Person Filing:
HealthCare Ventures II, L.P. ("HCV II"), HealthCare Partners
II, L.P. ("HCP II"), HealthCare Ventures III, L.P. ("HCV
III"), HealthCare Partners III, L.P. ("HCP III"), HealthCare
Ventures IV, L.P. ("HCV IV"), HealthCare Partners IV, L.P.
("HCP IV"), Dr. Cavanaugh and Messrs. Werner, Littlechild, and
Crouse. See attached Exhibit A which is a copy of their
agreement in writing to file this statement on behalf of each
of them.(1)
(b) Address of Principal Business Office or, if none, Residence:
The business address for HCV II, HCP II, HCV III, HCP III, HCV
IV, HCP IV and Dr. Cavanaugh and Messrs. Werner and Crouse is
Twin Towers at Metro Park, 379 Thornall Street, Edison, New
Jersey 08837. The business address for Mr. Littlechild is One
Kendall Square, Building 300, Cambridge, Massachusetts 02139.
(c) Citizenship:
HCV II, HCP II, HCV III, HCP III, HCV IV and HCP IV are
limited partnerships organized under the laws of the State of
Delaware. Dr. Cavanaugh and Messrs. Werner, Littlechild and
Crouse are each United States citizens.
(d) Title of Class of Securities:
Common Stock, par value $.01 ("Shares").
--------
(1) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are
general partners of each of HCP II, HCP III and HCP IV, which
are the general partner of each of HCV II, HCV III and HCV IV,
respectively the record holder of Issuer's securities.
<PAGE>
Page 13 of 17 Pages
(e) CUSIP Number:
09066Y107
Item 3. If this statement is filed pursuant to Rule 13d-1(b), or
13d-2(b), check whether the person filing is a:
Inapplicable.
Item 4. Ownership.
(a) Amount Beneficially Owned:
As of December 31, 1996: HCV II and HCP II beneficially owned
1,570,886 Shares of Issuer's Securities, consisting of
1,492,009 Shares of Issuer's Common Stock and immediately
exercisable warrants to purchase 42,980 Shares of Issuers
Common Stock. HCV III and HCP III beneficially owned 874,539
Shares of Issuer's Securities, consisting of 774,834 Shares of
Issuer's Common Stock and immediately exercisable warrants to
purchase 99,705 Shares of Issuer's Common Stock; HCV IV and
HCP IV beneficially owned 258,075 Shares of Issuer's
Securities, consisting of 228,504 Shares of Issuer's Common
Stock and immediately exercisable warrants to purchase 29,571
Shares of Issuer's Common Stock; and Dr. Cavanaugh and Messrs.
Werner, Littlechild and Crouse beneficially owned 2,703,500
Shares of Issuer's Securities, consisting of 2,495,347 Shares
of Common Stock and immediately exercisable warrants to
purchase 208,153 Shares of Issuer's Common Stock.
(b) Percent of Class:
As of December 31, 1996: the 1,570,886 Shares of Issuer's
Securities beneficially owned by HCV II and HCP II constitute
18.2% of Issuer's Shares outstanding; the 874,539 Shares of
Issuer's Securities beneficially owned by HCV III and HCP III
constitute 10.1% of the Issuer's Shares outstanding; the
258,075 Shares of Issuer's Securities beneficially owned by
HCV IV and HCP IV constitute 3.0% of Issuer's Shares
outstanding; and the 2,703,500 Shares of Issuer's Securities
beneficially owned by Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse constitute 30.9% of Issuer's Shares
outstanding.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
Inapplicable
<PAGE>
Page 14 of 17 Pages
(ii) shared power to vote or to direct the vote: HCV II,
HCP II, Dr. Cavanaugh and Messrs. Werner,
Littlechild, and Crouse share the power to vote or
direct the vote of those Shares owned by HCV II.
HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner,
Littlechild, and Crouse share the power to vote or
direct the vote of those Shares owned by HCV III.
HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner,
Littlechild, and Crouse share the power to vote or
direct the vote of those Shares owned by HCV IV.
(iii) sole power to dispose or to direct the disposition
of:
Inapplicable
(iv) shared power to dispose of or to direct the
disposition of: HCV II, HCP II, Dr. Cavanaugh and
Messrs. Werner, Littlechild and Crouse share the
power to dispose of or direct the disposition of
those Shares owned by HCV II.
HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse share the power to dispose of
or direct the disposition of those Shares owned by
HCV III.
HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse share the power to dispose of
or direct the disposition of those Shares owned by
HCV IV.
Item 5. Ownership of Five Percent or less of a Class:
Inapplicable.
Item 6. Ownership of More than Five Percent on Behalf of Another
Person:
Inapplicable.
Item 7. Identification and Classification of the Subsidiary Which
Acquired the Security Being Reported on by the Parent Holding
Company:
Inapplicable.
Item 8. Identification and Classification of Members of the Group:
Inapplicable.
<PAGE>
Page 15 of 17 Pages
Item 9. Notice of Dissolution of Group:
Inapplicable.
Item 10. Certification:
Inapplicable.
<PAGE>
Page 16 of 17 Pages
SIGNATURES
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.
<TABLE>
<S> <C>
Dated: February 13, 1997 HealthCare Ventures II, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners II, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Ventures III, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners III, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Ventures IV, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners IV, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey -------------------------------------------
James H. Cavanaugh, Ph.D.
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey -------------------------------------------
Harold R. Werner
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Cambridge, Massachusetts ------------------------------------------
John W. Littlechild
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey ------------------------------------------
William Crouse
</TABLE>
<PAGE>
Page 17 of 17 Pages
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13G and any future amendments thereto
reporting each of the undersigned's ownership of securities of BioTransplant
Incorporated and hereby affirm that such Schedule 13G is being filed on behalf
of each of the undersigned.
<TABLE>
<S> <C>
Dated: February 13, 1997 HealthCare Ventures II, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners II, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Ventures III, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners III, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Ventures IV, L.P.,
Edison, New Jersey by its General Partner, HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 HealthCare Partners IV, L.P.
Edison, New Jersey
By: /s/ Jeffrey Steinberg
-------------------------------------------
Administrative Partner
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey -------------------------------------------
James H. Cavanaugh, Ph.D.
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey -------------------------------------------
Harold R. Werner
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Cambridge, Massachusetts -------------------------------------------
John W. Littlechild
Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact
Edison, New Jersey -------------------------------------------
William Crouse
</TABLE>