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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D
Under the Securities Exchange Act of 1934
(Amendment No. 2 )*
---
Diacrin, Inc.
- --------------------------------------------------------------------------------
(Name of Issuer)
Common Stock, .01 par value
- --------------------------------------------------------------------------------
(Title of Class of Securities)
25243N103
- --------------------------------------------------------------------------------
(CUSIP Number)
Allison Newman, Esq., Bachner, Tally, Polevoy & Misher LLP
380 Madison Avenue, New York, New York 10017 (212) 687-7000
- --------------------------------------------------------------------------------
(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
1/1/98
- --------------------------------------------------------------------------------
(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box [ ].
Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-1(a) for other parties to whom copies are to be
sent.
(Continued on following page(s))
Page 1 of 21 Pages
The Exhibit Index appears on page 19.
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 2 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures II, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 3,196,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 3,196,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 3,196,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 24.1%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 3 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners II, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 3,196,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 3,196,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 3,196,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 24.1%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 4 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures III, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [X]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 994,078
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 994,078
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 994,078
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 7.5%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 5 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners III, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [X]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 994,078
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 994,078
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 994,078
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 7.5%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 6 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures IV, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [X]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 291,922
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 291,922
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 291,922
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 2.2%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 7 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners IV, L.P.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [X]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| Delaware
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 291,922
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 291,922
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 291,922
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 2.2%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 8 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| James H. Cavanaugh, Ph.D.
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| U.S.A.
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 4,482,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 4,482,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 4,482,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 33.8%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 9 of 21 Pages
----------- --- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| Harold R. Werner
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| U.S.A.
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 4,482,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 4,482,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 4,482,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 33.8%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 10 of 21 Pages
----------- ---- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| John W. Littlechild
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| U.S.A.
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 4,482,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 4,482,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 4,482,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 33.8%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 11 of 21 Pages
----------- ---- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| William Crouse
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| U.S.A.
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 4,482,385
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 4,482,385
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 4,482,385
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 33.8%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 12 of 21 Pages
----------- ---- ----
______________________ __________________
|
1 | NAME OF REPORTING PERSON
| S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| Mark Leschly
_______|______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | SOURCE OF FUNDS*
| N/A
_______|_______________________________________________________________________
|
5 | CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
| PURSUANT TO ITEMS 2(3) OR 2(e) [ ]
_______|_______________________________________________________________________
|
6 | CITIZENSHIP OR PLACE OR ORGANIZATION
| U.S.A.
_______|_______________________________________________________________________
| |
NUMBER OF | 7 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 8 | SHARED VOTING POWER
REPORTING | | 1,286,000
PERSON |_____|________________________________________________________
WITH | |
| 9 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 10 | SHARED DISPOSITIVE POWER
| | 1,286,000
_______________|_____|_________________________________________________________
|
11 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 1,286,000
_______|_______________________________________________________________________
|
12 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
13 | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
| 9.7%
_______|_______________________________________________________________________
|
14 | TYPE OF REPORTING PERSON
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 13 of 21 Pages
----------- ---- ----
______________________ __________________
Item 1. Security and Issuer
(a) Title of Class of Securities
Common Stock, $0.01 par value ("Shares").
(b) Name of Issuer
Diacrin, Inc.
(c) Address of Issuer's Principal Executive Officers
Building 96, 13th Street
Charlestown Navy Yard
Charlestown, Massachusetts 02129
Item 2. Identity and Background
(a) This statement if filed by HealthCare Ventures II, L.P.
("HCV II"), HealthCare Partners II, L.P. ("HCP II"),
HealthCare Ventures III, L.P. ("HCV III"), HealthCare
Partners III, L.P. ("HCP III"), HealthCare Ventures IV,
L.P. ("HCV IV"), HealthCare Partners IV, L.P. ("HCP IV"),
Dr. Cavanaugh and Messrs. Werner, Littlechild, Crouse and
Leschly. See attached Exhibit A which is a copy of their
agreement in writing to file this statement on behalf of
each of them.(1)
(b) The business address for HCV II, HCP II, HCV III, HCP III,
HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner and Crouse
is 44 Nassau Street, Princeton, New Jersey 08542. The
business address for Messrs. Littlechild and Leschly is One
Kendall Square, Building 300, Cambridge Massachusetts
02139.
(c) James H. Cavanaugh, Ph.D. is the President of
HealthCare Ventures LLC ("HCV"), the management company for
HCV II, HCV III and HCV IV. Messrs. Werner and Crouse are
each a Managing Director of HCV. Dr. Cavanaugh and Messrs.
Werner, Littlechild and Crouse are general partners of HCP
II and Dr. Cavanaugh and Messrs. Werner, Littlechild,
Crouse and Leschly are general partners of HCP III and HCP
IV. Mr. Littlechild is also a director of the Issuer.
(d) Each of HCV II, HCP II, HCV III, HCP III, HCV IV, HCP IV,
Dr. Cavanaugh and Messrs. Werner, Littlechild, Crouse and
Leschly have not, during the last five years, been
convicted in a criminal proceeding (excluding traffic
violations or similar
- --------
(1) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are general
partners of HCP II, which is the general partner of HCV II, and Dr.
Cavanaugh and Messrs. Werner, Littlechild, Crouse and Leschly are general
partners of each of HCP III and HCP IV, which is the general partner of
each of HCV III and HCV IV, respectively, the record holder of Issuer's
securities.
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 14 of 21 Pages
----------- ---- ----
______________________ __________________
misdemeanors).
(e) Each of HCV II, HCP II, HCV III, HCP III, HCV IV, HCP IV,
Dr. Cavanaugh and Messrs. Werner, Littlechild, Crouse and
Leschly have not been, during the last five years, a party
to a civil proceeding of a judicial or administrative body
of competent jurisdiction and as a result of any such
proceeding was or is subject to a judgment, decree or final
order enjoining future violations of, or prohibiting or
mandating activities subject to federal or state securities
laws or finding any violations with respect to such laws.
(f) HCV II, HCP II, HCV III, HCP III, HCV IV and HCP IV are
limited partnerships organized under the laws of the State
of Delaware. Dr. Cavanaugh and Messrs. Werner, Littlechild,
Crouse and Leschly are United States citizens.
Item 3. Source and Amount of Funds or Other Considerations
Not applicable.
Item 4. Purpose of Transaction
Not applicable.
Item 5. Interest in Securities of the Issuer
(a) As of January 1, 1998: (i) HCV II and HCP II beneficially
owned 3,196,385 of Issuer's Common Stock; (ii) HCV III and
HCP III beneficially owned 994,078 Shares of Issuer's
Common Stock; (iii) HCV IV and HCP IV beneficially owned
291,922 Shares of Issuer's Common Stock; (iv) Dr. Cavanaugh
and Messrs. Werner, Littlechild and Crouse beneficially
owned 4,482,385 Shares of Issuer's Common Stock; and (v)
Mr. Leschly beneficially owned 1,286,000 Shares of Issuer's
Common Stock.
As of January 1, 1998: (i) the 3,196,385 Shares of Issuer's
Common Stock beneficially owned by HCV II and HCP II
constitute 24.1% of Issuer's Shares, outstanding; (ii) the
994,078 Shares of Issuer's Common Stock beneficially owned
by HCV III and HCP III constitute 7.5% of Issuer's Shares
outstanding; (iii) the 291,922 Shares of Issuer's Common
Stock beneficially owned by HCV IV and HCP IV constitute
2.2% of Issuer's Shares outstanding; (iv) the 4,482,385
Shares of Issuer's Common Stock beneficially owned by Dr.
Cavanaugh and Messrs. Werner, Littlechild and Crouse
constitute 33.8% of Issuer's Shares outstanding; and (v)
the 1,286,000 Shares of Issuer's Common Stock beneficially
owned by Mr. Leschly constitute 9.7% of Issuer's Shares
outstanding.
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 15 of 21 Pages
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______________________ __________________
(b) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
Inapplicable.
(ii) shared power to vote or to direct the vote:
HCV II and HCP II share the power to vote or to
direct the vote of those Shares owned by HCV II. HCV
III and HCP III share the power to vote or to direct
the vote of those Shares owned by HCV III. HCV IV
and HCP IV share the power to vote or to direct the
vote of those Shares owned by HCV IV. Dr. Cavanaugh
and Messrs. Werner, Littlechild and Crouse share the
power to vote or to direct the vote of those Shares
owned by HCV II and Dr. Cavanaugh and Messrs.
Werner, Littlechild, Crouse and Leschly share the
power to vote or to direct the vote of those Shares
owned by HCV III and HCV IV.
(iii) sole power to dispose or to direct the disposition
of:
Inapplicable.
(iv) shared power to dispose of or to direct the
disposition of:
HCV II and HCP II share the power to dispose of or
to direct the disposition of those Shares owned by
HCV II. HCV III and HCP III share the power to
dispose of or to direct the disposition of those
Shares owned by HCV III. HCV IV and HCP IV share the
power to dispose of or to direct the disposition of
those Shares owned by HCV IV. Dr. Cavanaugh and
Messrs. Werner, Littlechild and Crouse share the
power to dispose of or to direct the disposition of
those Shares owned by HCV II, HCV III and HCV IV.
(c) On January 1, 1998, Mr. Leschly became a general partner of
each of HCP III and HCP IV and, accordingly, became the
beneficial ownership of those Shares owned by HCV III and
HCV IV.
(d) Inapplicable
(e) Inapplicable
Item 6. Contracts, Arrangements, Understandings or Relationship with
respect to Securities of the Issuer
On March 26, 1992, HCV III and HCV IV entered into an InterFund
Agreement which provides for HCV III and HCV IV to coordinate
their investment activities so as to acquire, hold and dispose of
identical securities in proportion to their respective contributed
capital.
<PAGE>
______________________ ___________________
CUSIP No. 25243N103 13D Page 16 of 21 Pages
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______________________ __________________
Item 7. Materials to Be Filed as Exhibits
(A) Agreement to Jointly File
(B) InterFund Agreement dated as of March 26, 1992 between HCV
III and HCV IV.*
*Previously filed as an Exhibit to the Schedule 13D filed by HCV III and HCV IV
on June 9, 1995.
<PAGE>
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CUSIP No. 25243N103 13D Page 17 of 21 Pages
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______________________ __________________
SIGNATURES
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.
Dated: February 10, 1998 HealthCare Ventures II, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners II, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures III, L.P.
Princeton, New Jersey by its General Partner,
HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners III, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures IV, L.P.
Princeton, New Jersey by its General Partner,
HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
<PAGE>
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CUSIP No. 25243N103 13D Page 18 of 21 Pages
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______________________ __________________
Dated: February 10, 1998 HealthCare Partners IV, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
--------------------------
A General Partner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ----------------------------
James H. Cavanaugh, Ph.D.
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ----------------------------
Harold R. Werner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ----------------------------
John W. Littlechild
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ----------------------------
William Crouse
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ----------------------------
Mark Leschly
<PAGE>
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CUSIP No. 25243N103 13D Page 19 of 21 Pages
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EXHIBIT INDEX
Exhibit Description Page No.
------- ----------- --------
Exhibit A Agreement to Jointly File 20
<PAGE>
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CUSIP No. 25243N103 13D Page 20 of 21 Pages
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EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13D
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13D and any future amendments thereto
reporting each of the undersigned's ownership of securities of Diacrin, Inc. and
hereby affirm that such Schedule 13D is being filed on behalf of each of the
undersigned.
Dated: February 10, 1998 HealthCare Ventures II, L.P.,
Princeton, New Jersey by its General Partner,
HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners II, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures III, L.P.
Princeton, New Jersey by its General Partner,
HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners III, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
<PAGE>
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CUSIP No. 25243N103 13D Page 21 of 21 Pages
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______________________ __________________
Dated: February 10, 1998 HealthCare Ventures IV, L.P.
Princeton, New Jersey by its General Partner,
HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners IV, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------------
A General Partner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------------
James H. Cavanaugh, Ph.D.
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------------
Harold R. Werner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------------
John W. Littlechild
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------------
William Crouse
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------------
Mark Leschly