<PAGE>
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
(Rule 13d-102)
INFORMATION TO BE INCLUDED IN STATEMENTS
FILED PURSUANT TO RULES 13D-1 (b) AND (c)
AND AMENDMENTS THERETO FILED
PURSUANT TO 13d-2(b)
(Amendment No. 1 )*
BioTransplant Incorporated
- --------------------------------------------------------------------------------
(Name of Issuer)
Common Stock, $.01 par value
- --------------------------------------------------------------------------------
(Title of Class of Securities)
09066Y107
- --------------------------------------------------------------------------------
(CUSIP Number)
* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
(Continued on following page(s))
Page 1 of 20 Pages
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 2 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures II, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 1,570,886
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 1,570,886
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 1,570,886
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 18.2%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 3 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners II, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 1,570,886
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 1,570,886
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 1,570,886
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 18.2%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 4 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures III, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 874,539
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 874,539
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 874,539
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 10.1%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 5 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners III, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 874,539
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 874,539
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 874,539
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 10.1%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 6 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Ventures IV, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 258,075
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 258,075
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 258,075
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 3.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 7 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| HealthCare Partners IV, L.P.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| Delaware
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 258,075
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 258,075
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 258,075
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 3.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| PN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 8 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| James H. Cavanaugh, Ph.D.
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| United States
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 2,703,500
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 2,703,500
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 2,703,500
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 31.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 9 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| Harold R. Werner
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| United States
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 2,703,500
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 2,703,500
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 2,703,500
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 31.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 10 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| William Crouse
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| United States
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 2,703,500
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 2,703,500
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 2,703,500
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 31.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 11 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| John W. Littlechild
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| United States
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 2,703,500
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 2,703,500
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 2,703,500
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 31.0%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
_______________________________________________________________________________
CUSIP No. 09066Y107 13G Page 12 of 20 Pages
_______________________________________________________________________________
|
1 | NAME OF REPORTING PERSON
| S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
|
| Mark Leschly
_______|_______________________________________________________________________
|
2 | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
| (b) [ ]
_______|_______________________________________________________________________
|
3 | SEC USE ONLY
_______|_______________________________________________________________________
|
4 | CITIZENSHIP OR PLACE OF ORGANIZATION
| United States
_______|________________________________________________________________________
| |
NUMBER OF | 5 | SOLE VOTING POWER
SHARES | |
BENEFICIALLY |_____|________________________________________________________
OWNED BY | |
EACH | 6 | SHARED VOTING POWER
REPORTING | | 1,132,614
PERSON WITH |_____|________________________________________________________
| |
| 7 | SOLE DISPOSITIVE POWER
| |
|_____|________________________________________________________
| |
| 8 | SHARED DISPOSITIVE POWER
| | 1,132,614
_______________|_____|_________________________________________________________
|
9 | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
| 1,132,614
_______|_______________________________________________________________________
|
10 | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
| CERTAIN SHARES* [ ]
_______|_______________________________________________________________________
|
11 | PERCENTAGE OF CLASS REPRESENTED BY AMOUNT IN ROW 9
| 13.8%
_______|_______________________________________________________________________
|
12 | TYPE OF REPORTING PERSON*
| IN
_______|_______________________________________________________________________
*SEE INSTRUCTIONS BEFORE FILLING OUT!
<PAGE>
Page 13 of 20 Pages
Item 1.
(a) Name of Issuer:
BioTransplant Incorporated
(b) Address of Issuer's Principal Executive Offices:
Charlestown Navy Yard, Building 75, Third Avenue
Charlestown, Massachusetts 02129
Item 2.
(a) Name of Person Filing:
HealthCare Ventures II, L.P. ("HCV II"), HealthCare Partners
II, L.P. ("HCP II"), HealthCare Ventures III, L.P. ("HCV
III"), HealthCare Partners III, L.P. ("HCP III"), HealthCare
Ventures IV, L.P. ("HCV IV"), HealthCare Partners IV, L.P.
("HCP IV"), Dr. Cavanaugh and Messrs. Werner, Littlechild,
Crouse and Leschly(1). See attached Exhibit A which is a copy
of their agreement in writing to file this statement on behalf
of each of them.(2)
(b) Address of Principal Business Office or, if none, Residence:
The business address for HCV II, HCP II, HCV III, HCP III, HCV
IV, HCP IV and Dr. Cavanaugh and Messrs. Werner and Crouse is
44 Nassau Street, Princeton, New Jersey 08542. The business
address for Messrs. Littlechild and Leschly is One Kendall
Square, Building 300, Cambridge, Massachusetts 02139.
(c) Citizenship:
HCV II, HCP II, HCV III, HCP III, HCV IV and HCP IV are
limited partnerships organized under the laws of the State of
Delaware. Dr. Cavanaugh and Messrs. Werner, Littlechild,
Crouse and Leschly are each United States citizens.
- ---------------
(1) Mr. Leschly became a general partner of each of HCP III and
HCP IV effective January 1, 1998.
(2) Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are
general partners of HCP II, which is the general partner of
HCV II, and Dr. Cavanaugh and Messrs. Werner, Littlechild,
Crouse and Leschly are general partners of each of HCP III and
HCP IV, the general partner of each of HCV III and HCV IV,
respectively, the record holder of Issuer's securities.
<PAGE>
Page 14 of 20 Pages
(d) Title of Class of Securities:
Common Stock, par value $.01 ("Shares").
(e) CUSIP Number:
09066Y107
Item 3. If this statement is filed pursuant to Rule 13d-1(b), or
13d-2(b), check whether the person filing is a:
Inapplicable.
Item 4. Ownership.
(a) Amount Beneficially Owned:
As of December 31, 1997: HCV II and HCP II beneficially owned
1,570,886 Shares of Issuer's Securities, consisting of
1,492,009 Shares of Issuer's Common Stock and immediately
exercisable warrants to purchase 78,877 Shares of Issuers
Common Stock; HCV III and HCP III beneficially owned 874,539
Shares of Issuer's Securities, consisting of 774,834 Shares of
Issuer's Common Stock and immediately exercisable warrants to
purchase 99,705 Shares of Issuer's Common Stock; HCV IV and
HCP IV beneficially owned 258,075 Shares of Issuer's
Securities, consisting of 228,504 Shares of Issuer's Common
Stock and immediately exercisable warrants to purchase 29,571
Shares of Issuer's Common Stock; Dr. Cavanaugh and Messrs.
Werner, Littlechild and Crouse beneficially owned 2,703,500
Shares of Issuer's Securities, consisting of 2,495,347 Shares
of Common Stock and immediately exercisable warrants to
purchase 208,153 Shares of Issuer's Common Stock; and Mr.
Leschly beneficially owned 1,132,614 Shares of Issuer's
Securities, consisting of 1,003,338 Shares of Issuer's Common
Stock and immediately exercisable warrants to purchase 129,276
Shares of Issuer's Common Stock.
(b) Percent of Class:
As of December 31, 1997: the 1,570,886 Shares of Issuer's
Securities beneficially owned by HCV II and HCP II constitute
18.2% of Issuer's Shares outstanding; the 874,539 Shares of
Issuer's Securities beneficially owned by HCV III and HCP III
constitute 10.1% of the Issuer's Shares outstanding; the
258,075 Shares of Issuer's Securities beneficially owned by
HCV IV and HCP IV constitute 3.0% of Issuer's Shares
outstanding; the 2,703,500 Shares of Issuer's Securities
beneficially owned by Dr. Cavanaugh and Messrs. Werner,
Littlechild and Crouse constitute 31.0% of Issuer's Shares
outstanding; and the 1,519,503 Shares of Issuer's Securities
beneficially owned by Mr. Leschly constitute 13.0% of Issuer's
Shares outstanding.
<PAGE>
Page 15 of 20 Pages
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
Inapplicable
(ii) shared power to vote or to direct the vote: HCV II,
HCP II, Dr. Cavanaugh and Messrs. Werner,
Littlechild, and Crouse share the power to vote or
direct the vote of those Shares owned by HCV II.
HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner,
Littlechild, Crouse and Leschly share the power to
vote or direct the vote of those Shares owned by HCV
III.
HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner,
Littlechild, Crouse and Leschly share the power to
vote or direct the vote of those Shares owned by HCV
IV.
(iii) sole power to dispose or to direct the disposition
of:
Inapplicable
(iv) shared power to dispose of or to direct the
disposition of: HCV II, HCP II, Dr. Cavanaugh and
Messrs. Werner, Littlechild and Crouse share the
power to dispose of or direct the disposition of
those Shares owned by HCV II.
HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner,
Littlechild, Crouse and Leschly share the power to
dispose of or direct the disposition of those Shares
owned by HCV III.
HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner,
Littlechild, Crouse and Leschly share the power to
dispose of or direct the disposition of those Shares
owned by HCV IV.
Item 5. Ownership of Five Percent or less of a Class:
Inapplicable.
Item 6. Ownership of More than Five Percent on Behalf of Another Person:
Inapplicable.
Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on by the Parent Holding Company:
Inapplicable.
<PAGE>
Page 16 of 20 Pages
Item 8. Identification and Classification of Members of the Group:
Inapplicable.
Item 9. Notice of Dissolution of Group:
Inapplicable.
Item 10. Certification:
Inapplicable.
<PAGE>
Page 17 of 20 Pages
SIGNATURES
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.
<TABLE>
<CAPTION>
<S> <C>
Dated: February 10, 1998 HealthCare Ventures II, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners II, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures III, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners III, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures IV, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners IV, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
James H. Cavanaugh, Ph.D.
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
Harold R. Werner
</TABLE>
<PAGE>
Page 18 of 20 Pages
<TABLE>
<CAPTION>
<S> <C>
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------
John W. Littlechild
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
William Crouse
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------
Mark Leschly
</TABLE>
<PAGE>
Page 19 of 20 Pages
EXHIBIT A
AGREEMENT
JOINT FILING OF SCHEDULE 13G
The undersigned hereby agree to jointly prepare and file with
regulatory authorities a Schedule 13G and any future amendments thereto
reporting each of the undersigned's ownership of securities of BioTransplant
Incorporated and hereby affirm that such Schedule 13G is being filed on behalf
of each of the undersigned.
<TABLE>
<CAPTION>
<S> <C>
Dated: February 10, 1998 HealthCare Ventures II, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners II, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners II, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures III, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners III, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners III, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Ventures IV, L.P.,
Princeton, New Jersey by its General Partner, HealthCare Partners IV, L.P.
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 HealthCare Partners IV, L.P.
Princeton, New Jersey
By: /s/ Jeffrey Steinberg
---------------------------
A General Partner
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
James H. Cavanaugh, Ph.D.
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
Harold R. Werner
</TABLE>
<PAGE>
Page 20 of 20 Pages
<TABLE>
<CAPTION>
<S> <C>
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------
John W. Littlechild
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Princeton, New Jersey ---------------------------
William Crouse
Dated: February 10, 1998 By: /s/ Jeffrey Steinberg
Cambridge, Massachusetts ---------------------------
Mark Leschly
</TABLE>
