<PAGE> 1
Prospectus Supplement No. 6 Filed pursuant to Rule 424(b)(3)
to Prospectus dated March 6, 2000 Registration No. 333-31354
ALKERMES, INC.
$250,000,000 3 3/4% CONVERTIBLE SUBORDINATED NOTES DUE 2007
1,845,018 SHARES OF COMMON STOCK
This prospectus supplement supplements the information contained in the
prospectus of Alkermes, Inc. dated March 6, 2000, as supplemented by Prospectus
Supplement No. 1 dated March 10, 2000, Prospectus Supplement No. 2 dated March
17, 2000, Prospectus Supplement No. 3 dated March 24, 2000, Prospectus
Supplement No. 4 dated April 5, 2000, and Prospectus Supplement No. 5 dated
April 13, 2000 relating to the potential resale from time to time of the 3 3/4%
Convertible Subordinated Notes due 2007 of Alkermes and the resale of shares of
common stock of Alkermes issuable upon conversion of the notes. This prospectus
supplement is not complete without, and may not be delivered or utilized except
in connection with, the prospectus, including any amendments or supplements
thereto.
The following table supplements the information set forth in the prospectus
under the caption "Selling Securityholders" with respect to the selling
securityholders and the respective principal amount of notes which are
beneficially owned and may be sold by each selling securityholder, and the
number of shares of common stock that may be sold by the selling securityholders
pursuant to this prospectus, as amended or supplemented:
<TABLE>
<CAPTION>
Number of Shares of
Common Stock Issued
Principal Amount of Upon Conversion of the
Notes Beneficially Notes that May be
Owned and Offered Offered (2)
<S> <C> <C>
Name of Selling Securityholder (1)
Amoco Corporation Master Trust $ 614,000 4,531
Hotel Union & Hotel Industry of Hawaii 260,000 1,918
ITG Inc. 112,000 826
Jefferies & Co. INCE 6,000 44
Lincoln National Convertible Securities Fund 2,500,000 18,450
Minnesota Bakers Union Pension Fund 27,000 199
The Estate of James Campbell 557,000 4,110
Tracor, Inc. Employees Retirement Plan 90,000 664
Viacom Pension Plan Master Trust 34,000 250
</TABLE>
(1) The information set forth herein is as of April 21, 2000 and will be
updated as required.
(2) Assumes conversion of the full principal amount of the notes held by such
holder at the initial conversion price of $135.50 per share of common
stock.
THE DATE OF THIS PROSPECTUS SUPPLEMENT IS APRIL 21, 2000
